Motif ID: Stat1

Z-value: 0.546


Transcription factors associated with Stat1:

Gene SymbolEntrez IDGene Name
Stat1 ENSMUSG00000026104.8 Stat1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat1mm10_v2_chr1_+_52119438_52119499-0.511.7e-06Click!


Activity profile for motif Stat1.

activity profile for motif Stat1


Sorted Z-values histogram for motif Stat1

Sorted Z-values for motif Stat1



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_93519499 8.916 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr11_+_78499087 7.430 ENSMUST00000017488.4
Vtn
vitronectin
chr12_+_74297474 5.657 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chrX_-_61185558 4.872 ENSMUST00000166381.1
Cdr1
cerebellar degeneration related antigen 1
chr17_-_68004075 4.342 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr15_-_37459327 4.268 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr15_-_37458523 4.194 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr4_-_136886187 3.906 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr9_+_20868628 3.844 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr3_-_80802789 3.801 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr11_+_101245996 3.697 ENSMUST00000129680.1
Ramp2
receptor (calcitonin) activity modifying protein 2
chr4_-_64046925 3.135 ENSMUST00000107377.3
Tnc
tenascin C
chr7_-_78577771 3.109 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr3_-_10440054 2.980 ENSMUST00000099223.4
ENSMUST00000029047.6
Snx16

sorting nexin 16

chr7_+_45783686 2.871 ENSMUST00000118564.1
ENSMUST00000133428.1
Lmtk3

lemur tyrosine kinase 3

chr11_+_82035569 2.862 ENSMUST00000000193.5
Ccl2
chemokine (C-C motif) ligand 2
chr16_-_42340595 2.775 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr4_+_43401232 2.748 ENSMUST00000125399.1
Rusc2
RUN and SH3 domain containing 2
chr7_+_45783883 2.724 ENSMUST00000072580.5
Lmtk3
lemur tyrosine kinase 3
chr7_+_24134148 2.436 ENSMUST00000056549.7
Zfp235
zinc finger protein 235
chr19_-_46327121 2.378 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr13_+_109903089 2.356 ENSMUST00000120664.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr11_+_82101836 2.276 ENSMUST00000000194.3
Ccl12
chemokine (C-C motif) ligand 12
chr17_+_34187545 2.209 ENSMUST00000170086.1
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr9_+_86743616 2.154 ENSMUST00000036426.6
Prss35
protease, serine, 35
chr17_-_45592569 1.924 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr17_+_34187789 1.912 ENSMUST00000041633.8
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr7_-_100856289 1.900 ENSMUST00000139604.1
Relt
RELT tumor necrosis factor receptor
chr16_+_91372783 1.899 ENSMUST00000023693.7
ENSMUST00000134491.2
ENSMUST00000117836.1
Ifnar2


interferon (alpha and beta) receptor 2


chr2_-_163750169 1.886 ENSMUST00000017841.3
Ada
adenosine deaminase
chrX_+_7728439 1.863 ENSMUST00000033489.7
Praf2
PRA1 domain family 2
chr2_+_150749036 1.842 ENSMUST00000094467.5
Entpd6
ectonucleoside triphosphate diphosphohydrolase 6
chr9_+_86743641 1.837 ENSMUST00000179574.1
Prss35
protease, serine, 35
chr10_+_40349265 1.770 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr2_+_178193075 1.730 ENSMUST00000103065.1
Phactr3
phosphatase and actin regulator 3
chr9_+_45117813 1.729 ENSMUST00000170998.1
ENSMUST00000093855.3
Scn2b

sodium channel, voltage-gated, type II, beta

chr1_-_155417394 1.716 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr8_-_70776650 1.701 ENSMUST00000034296.8
Pik3r2
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
chr7_+_24112314 1.639 ENSMUST00000120006.1
ENSMUST00000005413.3
Zfp112

zinc finger protein 112

chr16_+_91372865 1.575 ENSMUST00000089042.6
Ifnar2
interferon (alpha and beta) receptor 2
chr17_-_45592485 1.557 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr8_+_105326354 1.506 ENSMUST00000015000.5
ENSMUST00000098453.2
Tmem208

transmembrane protein 208

chr12_+_109544498 1.502 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr14_-_70627008 1.499 ENSMUST00000110984.2
Dmtn
dematin actin binding protein
chr1_-_155417283 1.449 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr8_-_70608261 1.410 ENSMUST00000049908.9
Ssbp4
single stranded DNA binding protein 4
chr8_-_105568298 1.402 ENSMUST00000005849.5
Agrp
agouti related protein
chrX_-_88760312 1.353 ENSMUST00000182943.1
Gm27000
predicted gene, 27000
chr5_+_136919137 1.338 ENSMUST00000181045.1
4933404O12Rik
RIKEN cDNA 4933404O12 gene
chr18_-_33463615 1.270 ENSMUST00000051087.8
Nrep
neuronal regeneration related protein
chr1_+_34005872 1.245 ENSMUST00000182296.1
Dst
dystonin
chr10_-_128409632 1.230 ENSMUST00000172348.1
ENSMUST00000166608.1
ENSMUST00000164199.1
ENSMUST00000171370.1
ENSMUST00000026439.7
Nabp2




nucleic acid binding protein 2




chr8_+_11728105 1.178 ENSMUST00000110909.2
ENSMUST00000033908.6
Arhgef7

Rho guanine nucleotide exchange factor (GEF7)

chr18_-_52529692 1.145 ENSMUST00000025409.7
Lox
lysyl oxidase
chr2_-_168712853 1.139 ENSMUST00000123156.1
ENSMUST00000156555.1
Atp9a

ATPase, class II, type 9A

chr1_+_37890477 1.138 ENSMUST00000027256.5
Mrpl30
mitochondrial ribosomal protein L30
chr7_-_13053684 1.097 ENSMUST00000182490.1
Mzf1
myeloid zinc finger 1
chr19_-_37207293 1.092 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr17_-_24527830 1.064 ENSMUST00000176353.1
ENSMUST00000176237.1
Traf7

TNF receptor-associated factor 7

chr9_+_107296682 1.049 ENSMUST00000168260.1
Cish
cytokine inducible SH2-containing protein
chr7_-_24316590 1.046 ENSMUST00000108436.1
ENSMUST00000032673.8
Zfp94

zinc finger protein 94

chr18_-_33463747 1.045 ENSMUST00000171533.1
Nrep
neuronal regeneration related protein
chr11_-_98729374 1.034 ENSMUST00000126565.1
ENSMUST00000100500.2
ENSMUST00000017354.6
Med24


mediator complex subunit 24


chr18_-_52529847 1.028 ENSMUST00000171470.1
Lox
lysyl oxidase
chrX_-_101419788 1.002 ENSMUST00000117901.1
ENSMUST00000120201.1
ENSMUST00000117637.1
ENSMUST00000134005.1
ENSMUST00000121520.1
Zmym3




zinc finger, MYM-type 3




chr18_+_37320374 0.993 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr17_-_24527925 0.984 ENSMUST00000176652.1
Traf7
TNF receptor-associated factor 7
chr3_-_96293953 0.967 ENSMUST00000029748.3
Fcgr1
Fc receptor, IgG, high affinity I
chr18_-_33464007 0.963 ENSMUST00000168890.1
Nrep
neuronal regeneration related protein
chr13_-_34002784 0.949 ENSMUST00000166354.1
ENSMUST00000076532.7
ENSMUST00000171034.1
Serpinb6a


serine (or cysteine) peptidase inhibitor, clade B, member 6a


chr8_+_70673364 0.940 ENSMUST00000146972.1
Lsm4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr16_-_74411776 0.937 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr7_-_45016224 0.936 ENSMUST00000085383.2
Scaf1
SR-related CTD-associated factor 1
chr10_-_95416850 0.919 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr9_+_86571965 0.918 ENSMUST00000034988.3
ENSMUST00000179212.1
Rwdd2a

RWD domain containing 2A

chr4_-_107178282 0.918 ENSMUST00000058585.7
Tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr3_+_96576984 0.914 ENSMUST00000148290.1
Gm16253
predicted gene 16253
chr7_+_28392916 0.912 ENSMUST00000003529.8
Paf1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chrX_-_47892396 0.893 ENSMUST00000153548.2
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr12_-_112671564 0.883 ENSMUST00000128300.2
Akt1
thymoma viral proto-oncogene 1
chr3_+_84925476 0.830 ENSMUST00000107675.1
Fbxw7
F-box and WD-40 domain protein 7
chr10_-_95417099 0.824 ENSMUST00000135822.1
Socs2
suppressor of cytokine signaling 2
chr11_-_45955183 0.816 ENSMUST00000109254.1
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr9_-_67539392 0.809 ENSMUST00000039662.8
Tln2
talin 2
chr7_-_105399991 0.805 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
Fam160a2




family with sequence similarity 160, member A2




chr4_+_148602527 0.783 ENSMUST00000105701.2
ENSMUST00000052060.6
Masp2

mannan-binding lectin serine peptidase 2

chr16_-_35871544 0.780 ENSMUST00000042665.8
Parp14
poly (ADP-ribose) polymerase family, member 14
chr15_-_53346118 0.739 ENSMUST00000077273.2
Ext1
exostoses (multiple) 1
chr12_-_100520778 0.731 ENSMUST00000062957.6
Ttc7b
tetratricopeptide repeat domain 7B
chr11_-_45955465 0.668 ENSMUST00000011398.6
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr17_-_47834682 0.664 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr13_-_34002740 0.658 ENSMUST00000167237.1
ENSMUST00000168400.1
Serpinb6a

serine (or cysteine) peptidase inhibitor, clade B, member 6a

chr7_-_28392688 0.656 ENSMUST00000003536.8
Med29
mediator complex subunit 29
chr15_-_54919961 0.649 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr8_+_70673198 0.642 ENSMUST00000034311.8
Lsm4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr7_-_126625676 0.637 ENSMUST00000032961.3
Nupr1
nuclear protein transcription regulator 1
chr18_+_42511496 0.626 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr18_-_3281036 0.620 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chrX_+_48623737 0.619 ENSMUST00000114936.1
Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr5_+_14025305 0.616 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr9_-_96719404 0.597 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr2_-_30093607 0.596 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr10_+_11609256 0.591 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr11_+_3488275 0.575 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr11_-_106579111 0.574 ENSMUST00000103070.2
Tex2
testis expressed gene 2
chr2_+_129100995 0.562 ENSMUST00000103205.4
ENSMUST00000028874.7
Polr1b

polymerase (RNA) I polypeptide B

chr16_-_91931643 0.557 ENSMUST00000023677.3
Atp5o
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr11_-_60046477 0.549 ENSMUST00000000310.7
ENSMUST00000102693.2
ENSMUST00000148512.1
Pemt


phosphatidylethanolamine N-methyltransferase


chr2_-_155729359 0.534 ENSMUST00000040833.4
Edem2
ER degradation enhancer, mannosidase alpha-like 2
chr16_-_20426322 0.528 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr11_+_78536393 0.506 ENSMUST00000050366.8
ENSMUST00000108275.1
Ift20

intraflagellar transport 20

chr11_+_78536355 0.505 ENSMUST00000128788.1
Ift20
intraflagellar transport 20
chr9_+_107296843 0.486 ENSMUST00000167072.1
Cish
cytokine inducible SH2-containing protein
chr5_-_34513892 0.476 ENSMUST00000114359.1
ENSMUST00000030991.7
ENSMUST00000087737.3
Tnip2


TNFAIP3 interacting protein 2


chr6_+_29468068 0.473 ENSMUST00000143101.1
Atp6v1f
ATPase, H+ transporting, lysosomal V1 subunit F
chr4_-_108032069 0.472 ENSMUST00000106709.2
Podn
podocan
chr15_-_54920115 0.455 ENSMUST00000171545.1
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chrX_+_106015699 0.453 ENSMUST00000033582.4
Cox7b
cytochrome c oxidase subunit VIIb
chr2_-_30093642 0.452 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr2_-_127584668 0.425 ENSMUST00000110368.2
ENSMUST00000077422.5
Zfp661

zinc finger protein 661

chr7_+_65693447 0.396 ENSMUST00000143508.1
Tm2d3
TM2 domain containing 3
chr17_-_27728889 0.386 ENSMUST00000167489.1
ENSMUST00000138970.1
ENSMUST00000114870.1
ENSMUST00000025054.2
Spdef



SAM pointed domain containing ets transcription factor



chr5_-_123140135 0.373 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr9_-_30922452 0.360 ENSMUST00000065112.6
Adamts15
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
chr8_-_124569696 0.355 ENSMUST00000063278.6
Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr9_+_54538984 0.354 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr3_-_57294880 0.344 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr7_+_24270420 0.329 ENSMUST00000108438.3
Zfp93
zinc finger protein 93
chr2_+_101886249 0.321 ENSMUST00000028584.7
Commd9
COMM domain containing 9
chr7_+_27591705 0.309 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr9_+_38718263 0.306 ENSMUST00000001544.5
ENSMUST00000118144.1
Vwa5a

von Willebrand factor A domain containing 5A

chr6_-_48048911 0.306 ENSMUST00000095944.3
Zfp777
zinc finger protein 777
chr13_-_46727932 0.299 ENSMUST00000021803.9
Nup153
nucleoporin 153
chr7_+_29768552 0.265 ENSMUST00000032802.4
Zfp84
zinc finger protein 84
chr10_+_18235030 0.258 ENSMUST00000181897.1
Gm10827
predicted gene 10827
chr1_+_171213969 0.244 ENSMUST00000005820.4
ENSMUST00000075469.5
ENSMUST00000155126.1
Nr1i3


nuclear receptor subfamily 1, group I, member 3


chr4_+_120666562 0.237 ENSMUST00000094814.4
Cited4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr10_-_78591945 0.228 ENSMUST00000040580.6
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr10_+_69925954 0.227 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr16_-_20425881 0.219 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr12_+_11265867 0.201 ENSMUST00000020931.5
Smc6
structural maintenance of chromosomes 6
chr16_+_17508947 0.184 ENSMUST00000023444.3
Lztr1
leucine-zipper-like transcriptional regulator, 1
chr1_+_136624901 0.174 ENSMUST00000047734.8
ENSMUST00000112046.1
Zfp281

zinc finger protein 281

chr10_+_69925800 0.173 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr10_+_69925766 0.169 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr10_-_18234930 0.162 ENSMUST00000052648.8
ENSMUST00000080860.6
ENSMUST00000173243.1
Ccdc28a


coiled-coil domain containing 28A


chr4_-_140617062 0.126 ENSMUST00000154979.1
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr13_-_67755132 0.104 ENSMUST00000091520.6
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr9_+_32224457 0.100 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr4_+_115088708 0.076 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
Pdzk1ip1



PDZK1 interacting protein 1



chr8_+_25601591 0.069 ENSMUST00000155861.1
Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr8_+_111033890 0.063 ENSMUST00000034441.7
Aars
alanyl-tRNA synthetase
chr11_+_101425068 0.063 ENSMUST00000040561.5
Rundc1
RUN domain containing 1
chr5_-_24445166 0.055 ENSMUST00000115043.1
ENSMUST00000115041.1
Fastk

Fas-activated serine/threonine kinase

chr7_-_100583072 0.052 ENSMUST00000152876.1
ENSMUST00000150042.1
Mrpl48

mitochondrial ribosomal protein L48

chrX_-_8252334 0.047 ENSMUST00000115595.1
ENSMUST00000033513.3
Ftsj1

FtsJ homolog 1 (E. coli)

chr11_+_53770014 0.043 ENSMUST00000108920.2
ENSMUST00000140866.1
ENSMUST00000108922.1
Irf1


interferon regulatory factor 1


chr3_+_97032416 0.041 ENSMUST00000132256.1
ENSMUST00000072600.6
Gja5

gap junction protein, alpha 5

chr5_-_24445254 0.032 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr7_-_81829431 0.021 ENSMUST00000026093.7
Btbd1
BTB (POZ) domain containing 1
chr5_-_140702241 0.007 ENSMUST00000077890.5
ENSMUST00000041783.7
ENSMUST00000142081.1
Iqce


IQ motif containing E


chr19_+_38481057 0.002 ENSMUST00000182481.1
Plce1
phospholipase C, epsilon 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 8.9 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
1.1 4.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
1.0 3.1 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
1.0 4.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.8 3.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.8 2.3 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.7 7.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302) liver regeneration(GO:0097421)
0.6 1.9 GO:0002314 germinal center B cell differentiation(GO:0002314) positive regulation of germinal center formation(GO:0002636) adenosine catabolic process(GO:0006154) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) purine nucleobase salvage(GO:0043096) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) xanthine metabolic process(GO:0046110) purine deoxyribonucleoside metabolic process(GO:0046122) regulation of adenosine receptor signaling pathway(GO:0060167) negative regulation of mucus secretion(GO:0070256)
0.6 3.7 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.6 2.9 GO:2000427 eosinophil chemotaxis(GO:0048245) T cell extravasation(GO:0072683) positive regulation of apoptotic cell clearance(GO:2000427)
0.5 3.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.5 1.5 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.5 3.5 GO:0015862 uridine transport(GO:0015862)
0.4 3.7 GO:0016198 axon choice point recognition(GO:0016198)
0.4 1.5 GO:0006624 vacuolar protein processing(GO:0006624)
0.4 1.1 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.4 0.4 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.3 1.7 GO:0046684 response to pyrethroid(GO:0046684)
0.3 1.0 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.3 2.3 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.2 2.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 7.3 GO:0034340 response to type I interferon(GO:0034340)
0.2 0.9 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.2 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.2 2.4 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 0.5 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 1.4 GO:0008343 adult feeding behavior(GO:0008343)
0.2 0.8 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 2.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 3.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.6 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.9 GO:0016584 nucleosome positioning(GO:0016584)
0.1 3.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 1.0 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 2.4 GO:0032026 response to magnesium ion(GO:0032026)
0.1 8.5 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.1 0.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.3 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.5 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.5 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 1.7 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 2.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 5.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.6 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.6 GO:0007000 nucleolus organization(GO:0007000)
0.1 1.2 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.1 1.6 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 1.5 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.3 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 1.6 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 1.7 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
0.0 0.7 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.7 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 1.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.8 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 2.3 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 1.5 GO:0006400 tRNA modification(GO:0006400)
0.0 1.0 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.6 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.5 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.0 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0 0.6 GO:0051591 response to cAMP(GO:0051591)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.0 2.9 GO:0044299 C-fiber(GO:0044299)
0.7 3.7 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.6 4.1 GO:0042825 TAP complex(GO:0042825)
0.4 1.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.4 3.0 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.3 1.2 GO:0031673 H zone(GO:0031673)
0.3 1.4 GO:0005796 Golgi lumen(GO:0005796)
0.3 1.0 GO:1902636 kinociliary basal body(GO:1902636)
0.2 1.2 GO:0070876 SOSS complex(GO:0070876)
0.2 0.9 GO:0090537 CERF complex(GO:0090537)
0.2 0.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 3.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 3.8 GO:0032279 asymmetric synapse(GO:0032279)
0.2 1.2 GO:0000322 storage vacuole(GO:0000322)
0.1 1.6 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.8 GO:0070695 FHF complex(GO:0070695)
0.1 2.2 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 6.1 GO:0005581 collagen trimer(GO:0005581)
0.1 0.8 GO:0005916 fascia adherens(GO:0005916)
0.1 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.1 2.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 7.6 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 2.7 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 15.1 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.5 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.1 3.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.0 4.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.9 3.5 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.7 3.7 GO:0097643 amylin receptor activity(GO:0097643)
0.6 3.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.6 3.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.5 2.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.5 3.1 GO:0045545 syndecan binding(GO:0045545)
0.5 1.5 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.5 8.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.4 2.8 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.3 1.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 0.9 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.3 1.6 GO:0042731 PH domain binding(GO:0042731)
0.2 1.7 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 1.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 8.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 1.0 GO:0019770 IgG receptor activity(GO:0019770)
0.2 0.8 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 1.9 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 3.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 1.8 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.1 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 2.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.8 GO:0001846 opsonin binding(GO:0001846)
0.1 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.9 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 4.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.6 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 2.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 4.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.6 GO:0002020 protease binding(GO:0002020)
0.0 0.0 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 10.1 GO:0008270 zinc ion binding(GO:0008270)
0.0 1.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.6 GO:0035091 phosphatidylinositol binding(GO:0035091)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.4 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 6.6 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 1.5 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 2.9 PID_IL23_PATHWAY IL23-mediated signaling events
0.1 3.1 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.4 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 1.2 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.1 2.7 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 2.8 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 2.8 PID_SHP2_PATHWAY SHP2 signaling
0.0 1.2 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.6 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.6 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 1.6 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.7 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.5 8.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 3.5 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.2 4.1 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 3.8 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 1.7 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 3.3 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.1 11.2 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.9 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.9 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.6 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 3.5 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 0.5 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.6 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 3.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 2.9 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.1 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 4.6 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.6 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.9 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.5 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling