Motif ID: Taf1

Z-value: 3.780


Transcription factors associated with Taf1:

Gene SymbolEntrez IDGene Name
Taf1 ENSMUSG00000031314.11 Taf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Taf1mm10_v2_chrX_+_101532734_1015327770.765.9e-16Click!


Activity profile for motif Taf1.

activity profile for motif Taf1


Sorted Z-values histogram for motif Taf1

Sorted Z-values for motif Taf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Taf1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_119047116 38.782 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr2_+_119047129 33.549 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr5_-_123749393 33.267 ENSMUST00000057795.5
ENSMUST00000111515.1
ENSMUST00000182309.1
Rsrc2


arginine/serine-rich coiled-coil 2


chr5_-_123749371 32.891 ENSMUST00000182955.1
ENSMUST00000182489.1
ENSMUST00000050827.7
Rsrc2


arginine/serine-rich coiled-coil 2


chr3_+_69004969 31.401 ENSMUST00000136502.1
ENSMUST00000107803.1
Smc4

structural maintenance of chromosomes 4

chr3_+_69004711 29.711 ENSMUST00000042901.8
Smc4
structural maintenance of chromosomes 4
chr10_+_79854618 25.877 ENSMUST00000165704.1
Ptbp1
polypyrimidine tract binding protein 1
chr7_+_59228743 24.770 ENSMUST00000107537.1
Ube3a
ubiquitin protein ligase E3A
chr10_+_79854658 22.463 ENSMUST00000171599.1
ENSMUST00000095457.4
Ptbp1

polypyrimidine tract binding protein 1

chr9_+_80067452 21.087 ENSMUST00000165607.2
Senp6
SUMO/sentrin specific peptidase 6
chr5_+_23434435 20.558 ENSMUST00000094962.2
ENSMUST00000115128.1
Kmt2e

lysine (K)-specific methyltransferase 2E

chr6_+_38433913 20.466 ENSMUST00000160583.1
Ubn2
ubinuclein 2
chr12_-_101083653 20.422 ENSMUST00000048305.8
ENSMUST00000163095.1
Smek1

SMEK homolog 1, suppressor of mek1 (Dictyostelium)

chrX_-_103483205 20.274 ENSMUST00000127786.2
Xist
inactive X specific transcripts
chr19_+_34922351 19.026 ENSMUST00000087341.5
Kif20b
kinesin family member 20B
chr12_+_83632208 18.075 ENSMUST00000048155.9
ENSMUST00000182618.1
ENSMUST00000183154.1
ENSMUST00000182036.1
ENSMUST00000182347.1
Rbm25




RNA binding motif protein 25




chr7_+_123123870 17.870 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chrX_-_103981242 17.624 ENSMUST00000121153.1
ENSMUST00000070705.4
Rlim

ring finger protein, LIM domain interacting

chr3_-_84220853 17.538 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
Trim2


tripartite motif-containing 2


chr18_-_6241486 17.367 ENSMUST00000025083.7
Kif5b
kinesin family member 5B
chr9_-_72491939 17.274 ENSMUST00000185151.1
ENSMUST00000085358.5
ENSMUST00000184125.1
ENSMUST00000183574.1
ENSMUST00000184831.1
Tex9




testis expressed gene 9




chr9_+_122951051 17.007 ENSMUST00000040717.5
Kif15
kinesin family member 15
chr2_+_119618717 16.921 ENSMUST00000028771.7
Nusap1
nucleolar and spindle associated protein 1
chr15_-_86033777 16.729 ENSMUST00000016172.7
Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr4_-_62208426 16.704 ENSMUST00000068822.3
Zfp37
zinc finger protein 37
chr18_-_6241470 16.693 ENSMUST00000163210.1
Kif5b
kinesin family member 5B
chr4_-_116627478 16.544 ENSMUST00000081182.4
ENSMUST00000030457.5
Nasp

nuclear autoantigenic sperm protein (histone-binding)

chr2_+_35109482 16.457 ENSMUST00000028235.4
ENSMUST00000156933.1
ENSMUST00000028237.8
Cep110


centrosomal protein 110


chrX_-_60403947 16.439 ENSMUST00000033480.6
ENSMUST00000101527.2
Atp11c

ATPase, class VI, type 11C

chrX_-_108834303 16.315 ENSMUST00000101283.3
ENSMUST00000150434.1
Brwd3

bromodomain and WD repeat domain containing 3

chr5_+_108065742 16.262 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
Mtf2


metal response element binding transcription factor 2


chr12_+_71015966 15.513 ENSMUST00000046305.5
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr4_+_21848039 14.994 ENSMUST00000098238.2
ENSMUST00000108229.1
Sfrs18

serine/arginine-rich splicing factor 18

chr2_+_52072823 14.855 ENSMUST00000112693.2
ENSMUST00000069794.5
Rif1

Rap1 interacting factor 1 homolog (yeast)

chr12_-_98901478 14.646 ENSMUST00000065716.6
Eml5
echinoderm microtubule associated protein like 5
chr10_+_41519493 14.631 ENSMUST00000019962.8
Cd164
CD164 antigen
chr3_-_133544390 14.325 ENSMUST00000098603.3
Tet2
tet methylcytosine dioxygenase 2
chr3_-_95217690 14.015 ENSMUST00000107209.1
Gabpb2
GA repeat binding protein, beta 2
chr6_+_149408973 13.949 ENSMUST00000086829.4
ENSMUST00000111513.2
Bicd1

bicaudal D homolog 1 (Drosophila)

chr7_-_98656530 13.470 ENSMUST00000038359.4
2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr11_-_77078404 13.203 ENSMUST00000102494.1
Ccdc55
coiled-coil domain containing 55
chr6_+_83914353 13.128 ENSMUST00000113835.3
ENSMUST00000032088.7
ENSMUST00000113836.3
Zfml


zinc finger, matrin-like


chr12_+_4917376 13.024 ENSMUST00000045664.5
Atad2b
ATPase family, AAA domain containing 2B
chr17_-_71526819 13.009 ENSMUST00000024851.9
Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr10_+_108162358 12.957 ENSMUST00000070663.5
Ppp1r12a
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chrX_+_57053549 12.802 ENSMUST00000114751.2
ENSMUST00000088652.5
Htatsf1

HIV TAT specific factor 1

chr15_-_58076456 12.703 ENSMUST00000070143.6
ENSMUST00000110168.1
Zhx1

zinc fingers and homeoboxes 1

chr9_+_25252439 12.669 ENSMUST00000115272.2
ENSMUST00000165594.2
Sept7

septin 7

chr5_+_108065696 12.657 ENSMUST00000172045.1
Mtf2
metal response element binding transcription factor 2
chr4_+_148039035 12.631 ENSMUST00000097788.4
Mthfr
5,10-methylenetetrahydrofolate reductase
chr1_+_178405881 12.630 ENSMUST00000027775.7
Efcab2
EF-hand calcium binding domain 2
chr18_-_10610346 12.565 ENSMUST00000025142.5
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr4_-_34882919 12.549 ENSMUST00000098163.2
ENSMUST00000047950.5
Zfp292

zinc finger protein 292

chr13_+_96542727 12.547 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr3_-_95217877 12.164 ENSMUST00000136139.1
Gabpb2
GA repeat binding protein, beta 2
chr9_+_72274860 12.080 ENSMUST00000184036.1
ENSMUST00000184517.1
ENSMUST00000098576.3
Zfp280d


zinc finger protein 280D


chr16_-_33056174 11.935 ENSMUST00000115100.1
ENSMUST00000040309.8
Iqcg

IQ motif containing G

chrX_-_95026671 11.853 ENSMUST00000096367.3
Spin4
spindlin family, member 4
chr2_+_172549581 11.814 ENSMUST00000030391.2
Tfap2c
transcription factor AP-2, gamma
chr9_+_72274966 11.748 ENSMUST00000183410.1
Zfp280d
zinc finger protein 280D
chr3_+_40800013 11.713 ENSMUST00000026858.5
ENSMUST00000170825.1
Plk4

polo-like kinase 4

chr3_-_69004565 11.597 ENSMUST00000169064.1
Ift80
intraflagellar transport 80
chr7_-_127042420 11.551 ENSMUST00000032915.6
Kif22
kinesin family member 22
chr3_-_69004503 11.507 ENSMUST00000107812.1
Ift80
intraflagellar transport 80
chr15_+_25622525 11.347 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr1_-_166002613 11.316 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
Pou2f1



POU domain, class 2, transcription factor 1



chr1_-_58424042 11.208 ENSMUST00000034868.7
Clk1
CDC-like kinase 1
chrX_-_113185485 11.203 ENSMUST00000026607.8
ENSMUST00000113388.2
Chm

choroidermia

chrX_-_41911877 11.158 ENSMUST00000047037.8
Thoc2
THO complex 2
chr12_-_4233958 10.976 ENSMUST00000111169.3
ENSMUST00000020981.5
Cenpo

centromere protein O

chr3_-_69004475 10.966 ENSMUST00000154741.1
ENSMUST00000148031.1
Ift80

intraflagellar transport 80

chrX_+_151520655 10.946 ENSMUST00000112666.1
ENSMUST00000168501.1
ENSMUST00000112662.2
Phf8


PHD finger protein 8


chrX_+_13280970 10.940 ENSMUST00000000804.6
Ddx3x
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
chr11_-_94321957 10.833 ENSMUST00000166312.1
ENSMUST00000107821.2
ENSMUST00000021226.7
ENSMUST00000107820.1
Luc7l3



LUC7-like 3 (S. cerevisiae)



chr4_-_132422394 10.698 ENSMUST00000152271.1
ENSMUST00000084170.5
Phactr4

phosphatase and actin regulator 4

chr1_+_150393250 10.683 ENSMUST00000119161.2
Tpr
translocated promoter region
chr19_+_41482632 10.640 ENSMUST00000067795.5
Lcor
ligand dependent nuclear receptor corepressor
chr15_+_34082664 10.624 ENSMUST00000022865.9
Mtdh
metadherin
chr3_+_40800054 10.524 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr8_-_111259192 10.489 ENSMUST00000169020.1
ENSMUST00000003404.8
Glg1

golgi apparatus protein 1

chr1_-_133661318 10.485 ENSMUST00000027736.6
ENSMUST00000179598.1
Zc3h11a
Zbed6
zinc finger CCCH type containing 11A
zinc finger, BED domain containing 6
chr18_-_10610048 10.470 ENSMUST00000115864.1
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr5_-_9161692 10.457 ENSMUST00000183973.1
ENSMUST00000184372.1
ENSMUST00000095017.4
ENSMUST00000071921.6
Dmtf1



cyclin D binding myb-like transcription factor 1



chrX_-_23365044 10.393 ENSMUST00000115313.1
Klhl13
kelch-like 13
chr18_-_10610124 10.305 ENSMUST00000097670.3
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chrX_-_111463149 10.305 ENSMUST00000096348.3
ENSMUST00000113428.2
Rps6ka6

ribosomal protein S6 kinase polypeptide 6

chr11_-_85235065 10.246 ENSMUST00000018625.9
Appbp2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr7_+_97579868 10.208 ENSMUST00000042399.7
ENSMUST00000107153.1
Rsf1

remodeling and spacing factor 1

chr9_-_66919646 10.183 ENSMUST00000041139.7
Rab8b
RAB8B, member RAS oncogene family
chr12_-_46818749 10.100 ENSMUST00000021438.6
Nova1
neuro-oncological ventral antigen 1
chr2_+_173659760 10.097 ENSMUST00000029024.3
Rab22a
RAB22A, member RAS oncogene family
chr2_+_23069057 10.072 ENSMUST00000114526.1
ENSMUST00000114529.2
Acbd5

acyl-Coenzyme A binding domain containing 5

chr6_+_113531675 10.055 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr1_-_143702832 10.054 ENSMUST00000018337.7
Cdc73
cell division cycle 73, Paf1/RNA polymerase II complex component
chr5_+_76588663 10.052 ENSMUST00000121979.1
Cep135
centrosomal protein 135
chr3_-_116423930 10.045 ENSMUST00000106491.2
Cdc14a
CDC14 cell division cycle 14A
chrX_-_105929206 10.035 ENSMUST00000134381.1
ENSMUST00000154866.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr14_+_56668242 10.017 ENSMUST00000116468.1
Mphosph8
M-phase phosphoprotein 8
chr14_-_26534870 10.002 ENSMUST00000139075.1
ENSMUST00000102956.1
Slmap

sarcolemma associated protein

chr1_+_74601548 9.958 ENSMUST00000087186.4
Stk36
serine/threonine kinase 36
chrX_-_105929333 9.950 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
Atrx


alpha thalassemia/mental retardation syndrome X-linked homolog (human)


chrX_-_105929397 9.933 ENSMUST00000113573.1
ENSMUST00000130980.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr4_-_135873546 9.922 ENSMUST00000142585.1
Pnrc2
proline-rich nuclear receptor coactivator 2
chr10_+_115384951 9.871 ENSMUST00000036044.8
Zfc3h1
zinc finger, C3H1-type containing
chr5_+_3928033 9.871 ENSMUST00000143365.1
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr16_+_37011758 9.761 ENSMUST00000071452.5
ENSMUST00000054034.6
Polq

polymerase (DNA directed), theta

chr4_-_11254248 9.755 ENSMUST00000044616.3
ENSMUST00000108319.2
ENSMUST00000108318.2
Ints8


integrator complex subunit 8


chr11_+_29172890 9.633 ENSMUST00000102856.2
ENSMUST00000020755.5
Smek2

SMEK homolog 2, suppressor of mek1 (Dictyostelium)

chr11_-_17953861 9.610 ENSMUST00000076661.6
Etaa1
Ewing's tumor-associated antigen 1
chr1_-_119837613 9.578 ENSMUST00000064091.5
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chrX_+_42149288 9.551 ENSMUST00000115073.2
ENSMUST00000115072.1
Stag2

stromal antigen 2

chr13_-_103920295 9.512 ENSMUST00000169083.1
Erbb2ip
Erbb2 interacting protein
chr4_+_148039097 9.490 ENSMUST00000141283.1
Mthfr
5,10-methylenetetrahydrofolate reductase
chr5_+_3928267 9.448 ENSMUST00000044492.8
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr13_-_47105790 9.441 ENSMUST00000129352.1
Dek
DEK oncogene (DNA binding)
chr7_+_12478319 9.433 ENSMUST00000151933.1
Zfp606
zinc finger protein 606
chr10_+_7681197 9.350 ENSMUST00000165952.1
Lats1
large tumor suppressor
chr4_-_132422484 9.325 ENSMUST00000102568.3
Phactr4
phosphatase and actin regulator 4
chr8_+_41239718 9.311 ENSMUST00000045218.7
Pcm1
pericentriolar material 1
chr14_+_47276910 9.299 ENSMUST00000065562.4
Socs4
suppressor of cytokine signaling 4
chrX_-_111463043 9.295 ENSMUST00000065976.5
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr1_+_64532790 9.253 ENSMUST00000049932.5
ENSMUST00000087366.4
ENSMUST00000171164.1
Creb1


cAMP responsive element binding protein 1


chr1_-_119837338 9.205 ENSMUST00000163435.1
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr16_+_84834901 9.176 ENSMUST00000114184.1
Gabpa
GA repeat binding protein, alpha
chrX_+_103356464 9.127 ENSMUST00000116547.2
Chic1
cysteine-rich hydrophobic domain 1
chr1_-_166002591 9.126 ENSMUST00000111429.4
ENSMUST00000176800.1
Pou2f1

POU domain, class 2, transcription factor 1

chr7_-_80803253 9.120 ENSMUST00000167377.1
Iqgap1
IQ motif containing GTPase activating protein 1
chr11_+_23665615 9.108 ENSMUST00000109525.1
ENSMUST00000020520.4
Pus10

pseudouridylate synthase 10

chr1_-_162740350 9.094 ENSMUST00000182331.1
ENSMUST00000183011.1
ENSMUST00000182593.1
ENSMUST00000182149.1
Prrc2c



proline-rich coiled-coil 2C



chr9_+_3404058 9.051 ENSMUST00000027027.5
Cwf19l2
CWF19-like 2, cell cycle control (S. pombe)
chr5_-_30155101 9.045 ENSMUST00000156859.1
Hadha
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
chrX_-_37110257 9.041 ENSMUST00000076265.6
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr5_-_21701332 9.025 ENSMUST00000115217.1
ENSMUST00000060899.8
Napepld

N-acyl phosphatidylethanolamine phospholipase D

chr3_+_86224665 9.024 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chr14_+_27428790 9.013 ENSMUST00000022450.4
D14Abb1e
DNA segment, Chr 14, Abbott 1 expressed
chrX_+_159255782 8.986 ENSMUST00000126686.1
ENSMUST00000033671.6
Rps6ka3

ribosomal protein S6 kinase polypeptide 3

chr13_-_104816908 8.962 ENSMUST00000022228.6
Cwc27
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr1_+_74601441 8.961 ENSMUST00000087183.4
ENSMUST00000148456.1
ENSMUST00000113694.1
Stk36


serine/threonine kinase 36


chr12_-_102878406 8.926 ENSMUST00000045652.6
Btbd7
BTB (POZ) domain containing 7
chr9_-_65885024 8.911 ENSMUST00000122410.1
ENSMUST00000117083.1
Trip4

thyroid hormone receptor interactor 4

chr9_-_42124276 8.846 ENSMUST00000060989.8
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr19_+_3768112 8.824 ENSMUST00000005518.9
ENSMUST00000113967.1
ENSMUST00000152935.1
ENSMUST00000176262.1
ENSMUST00000176407.1
ENSMUST00000176926.1
ENSMUST00000176512.1
Suv420h1






suppressor of variegation 4-20 homolog 1 (Drosophila)






chr7_+_12478293 8.821 ENSMUST00000098822.3
Zfp606
zinc finger protein 606
chr16_+_32332238 8.776 ENSMUST00000115151.3
Ubxn7
UBX domain protein 7
chr7_-_92669917 8.690 ENSMUST00000119954.1
Pcf11
cleavage and polyadenylation factor subunit homolog (S. cerevisiae)
chr18_-_46280820 8.669 ENSMUST00000025354.3
Pggt1b
protein geranylgeranyltransferase type I, beta subunit
chr19_+_53600377 8.632 ENSMUST00000025930.9
Smc3
structural maintenance of chromosomes 3
chr2_-_172370506 8.593 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr11_-_100472725 8.574 ENSMUST00000056665.3
Klhl11
kelch-like 11
chr17_+_80944611 8.553 ENSMUST00000025092.4
Tmem178
transmembrane protein 178
chr3_+_156561950 8.538 ENSMUST00000041425.5
ENSMUST00000106065.1
Negr1

neuronal growth regulator 1

chr6_+_86404336 8.533 ENSMUST00000113713.2
ENSMUST00000113708.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr13_-_111808938 8.532 ENSMUST00000109267.2
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr1_+_127774164 8.530 ENSMUST00000027587.8
ENSMUST00000112570.1
Ccnt2

cyclin T2

chr3_+_116594959 8.518 ENSMUST00000029571.8
Sass6
spindle assembly 6 homolog (C. elegans)
chr3_-_95217741 8.517 ENSMUST00000107204.1
Gabpb2
GA repeat binding protein, beta 2
chr9_-_104262900 8.508 ENSMUST00000035170.6
Dnajc13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr10_+_94036001 8.490 ENSMUST00000020208.4
Fgd6
FYVE, RhoGEF and PH domain containing 6
chr4_-_70410422 8.456 ENSMUST00000144099.1
Cdk5rap2
CDK5 regulatory subunit associated protein 2
chr14_+_21500879 8.435 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr1_+_130717320 8.405 ENSMUST00000049813.4
Yod1
YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae)
chrX_-_104413825 8.402 ENSMUST00000033695.5
Abcb7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr1_-_36939521 8.385 ENSMUST00000027290.5
Tmem131
transmembrane protein 131
chr12_+_16810940 8.377 ENSMUST00000020908.7
E2f6
E2F transcription factor 6
chr2_-_10048580 8.373 ENSMUST00000026888.4
Taf3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_+_23069210 8.369 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr2_+_128818104 8.348 ENSMUST00000110325.1
Tmem87b
transmembrane protein 87B
chr12_+_59066908 8.342 ENSMUST00000021381.4
Pnn
pinin
chr15_-_58076183 8.290 ENSMUST00000177276.1
ENSMUST00000175805.2
ENSMUST00000177504.2
ENSMUST00000176076.1
ENSMUST00000177176.1
Zhx1

9130401M01Rik


zinc fingers and homeoboxes 1

RIKEN cDNA 9130401M01 gene


chr1_-_162740540 8.287 ENSMUST00000028016.9
ENSMUST00000182660.1
Prrc2c

proline-rich coiled-coil 2C

chr11_-_62457289 8.259 ENSMUST00000069456.4
ENSMUST00000018645.6
Ncor1

nuclear receptor co-repressor 1

chr19_-_23273893 8.239 ENSMUST00000087556.5
Smc5
structural maintenance of chromosomes 5
chr3_+_51415986 8.227 ENSMUST00000029303.7
Naa15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr13_-_100104064 8.187 ENSMUST00000038104.5
Bdp1
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chr4_+_12089373 8.179 ENSMUST00000095143.2
ENSMUST00000063839.5
Rbm12b2

RNA binding motif protein 12 B2

chrX_+_42149534 8.161 ENSMUST00000127618.1
Stag2
stromal antigen 2
chr4_-_94979063 8.137 ENSMUST00000075872.3
Mysm1
myb-like, SWIRM and MPN domains 1
chr5_+_15934685 8.058 ENSMUST00000078272.6
ENSMUST00000180204.1
ENSMUST00000167946.2
ENSMUST00000101581.3
ENSMUST00000039370.7
Cacna2d1




calcium channel, voltage-dependent, alpha2/delta subunit 1




chrX_-_142966709 8.042 ENSMUST00000041317.2
Ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr4_-_121215071 8.041 ENSMUST00000056635.5
Rlf
rearranged L-myc fusion sequence
chr4_+_49521176 7.991 ENSMUST00000042964.6
ENSMUST00000107696.1
Zfp189

zinc finger protein 189

chr9_+_70542872 7.985 ENSMUST00000049263.7
Sltm
SAFB-like, transcription modulator
chr9_-_95511897 7.971 ENSMUST00000079659.5
ENSMUST00000078374.6
U2surp

U2 snRNP-associated SURP domain containing

chr2_+_71453276 7.952 ENSMUST00000037210.8
Metap1d
methionyl aminopeptidase type 1D (mitochondrial)
chr14_-_72709986 7.938 ENSMUST00000089017.5
Fndc3a
fibronectin type III domain containing 3A
chr1_-_10232670 7.935 ENSMUST00000088615.4
ENSMUST00000131556.1
Arfgef1

ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)

chr4_+_12140263 7.917 ENSMUST00000050069.2
ENSMUST00000069128.7
Rbm12b1

RNA binding motif protein 12 B1

chr18_+_34624621 7.916 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr10_-_62792243 7.914 ENSMUST00000020268.5
Ccar1
cell division cycle and apoptosis regulator 1
chr14_-_105176860 7.913 ENSMUST00000163545.1
Rbm26
RNA binding motif protein 26
chr1_-_119836999 7.879 ENSMUST00000163621.1
ENSMUST00000168303.1
Ptpn4

protein tyrosine phosphatase, non-receptor type 4

chr13_+_34875488 7.847 ENSMUST00000077853.3
Prpf4b
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
chr2_+_128818295 7.842 ENSMUST00000178354.1
ENSMUST00000152210.1
Tmem87b

transmembrane protein 87B

chr9_-_107770945 7.800 ENSMUST00000183248.1
ENSMUST00000182022.1
ENSMUST00000035199.6
ENSMUST00000182659.1
Rbm5



RNA binding motif protein 5



chrX_-_147554050 7.798 ENSMUST00000112819.2
ENSMUST00000136789.1
Lrch2

leucine-rich repeats and calponin homology (CH) domain containing 2

chr16_+_31664130 7.779 ENSMUST00000023454.5
Dlg1
discs, large homolog 1 (Drosophila)
chr15_-_79328154 7.771 ENSMUST00000166977.2
Pla2g6
phospholipase A2, group VI
chrX_+_42067836 7.765 ENSMUST00000115094.1
Xiap
X-linked inhibitor of apoptosis
chr9_+_80066939 7.750 ENSMUST00000164859.1
Senp6
SUMO/sentrin specific peptidase 6
chr6_+_86404219 7.716 ENSMUST00000095754.3
ENSMUST00000095753.2
Tia1

cytotoxic granule-associated RNA binding protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.8 44.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
7.6 61.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
7.5 29.9 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
7.1 28.3 GO:0070829 heterochromatin maintenance(GO:0070829)
6.8 20.4 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
6.8 20.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
6.7 33.3 GO:0034421 post-translational protein acetylation(GO:0034421)
6.3 19.0 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
6.3 31.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
6.1 18.2 GO:0035574 histone H4-K20 demethylation(GO:0035574)
5.8 17.4 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
5.8 28.9 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
5.6 16.7 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
5.3 53.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
5.3 21.1 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
5.0 20.0 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
4.8 33.9 GO:0090234 regulation of kinetochore assembly(GO:0090234)
4.7 18.9 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
4.7 14.0 GO:0072554 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
4.6 13.9 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
4.5 45.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
4.5 13.6 GO:0019858 cytosine metabolic process(GO:0019858)
4.4 22.2 GO:0046601 positive regulation of centriole replication(GO:0046601)
4.1 8.2 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
3.9 11.8 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
3.9 15.6 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
3.8 15.0 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
3.7 22.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
3.6 14.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
3.6 10.7 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
3.5 10.6 GO:0021698 cerebellar cortex structural organization(GO:0021698)
3.5 17.6 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
3.5 17.6 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
3.5 3.5 GO:0060699 regulation of endoribonuclease activity(GO:0060699) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
3.4 13.5 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
3.3 6.7 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
3.3 33.0 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
3.2 22.3 GO:0030242 pexophagy(GO:0030242)
3.2 12.6 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
3.1 12.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
3.1 9.3 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
3.1 34.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
3.1 9.3 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
3.0 12.0 GO:0097494 regulation of vesicle size(GO:0097494)
2.9 11.7 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
2.9 20.4 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
2.9 8.6 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
2.8 8.5 GO:0019085 early viral transcription(GO:0019085)
2.8 22.1 GO:0018344 protein geranylgeranylation(GO:0018344)
2.7 8.2 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
2.7 8.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
2.7 24.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
2.7 8.1 GO:0099547 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
2.7 18.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
2.6 7.7 GO:0070650 actin filament bundle distribution(GO:0070650)
2.6 10.3 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
2.6 7.7 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
2.6 35.9 GO:0060009 Sertoli cell development(GO:0060009)
2.5 7.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
2.5 9.9 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
2.5 24.8 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
2.4 12.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
2.4 7.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
2.3 4.6 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
2.3 6.8 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
2.2 11.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
2.2 6.6 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
2.2 6.6 GO:0019046 release from viral latency(GO:0019046)
2.2 12.9 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
2.1 8.6 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
2.1 8.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
2.1 6.3 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
2.0 12.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
2.0 10.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
2.0 15.9 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
2.0 5.9 GO:1990859 cellular response to endothelin(GO:1990859)
1.9 7.8 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.9 5.8 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
1.9 15.4 GO:0001542 ovulation from ovarian follicle(GO:0001542)
1.9 13.4 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
1.9 13.4 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
1.9 26.5 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
1.8 11.0 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
1.8 12.8 GO:0016584 nucleosome positioning(GO:0016584)
1.8 5.5 GO:0042275 error-free postreplication DNA repair(GO:0042275)
1.8 9.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.8 5.4 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
1.8 9.0 GO:1903998 regulation of eating behavior(GO:1903998)
1.8 19.6 GO:2000381 negative regulation of mesoderm development(GO:2000381)
1.8 14.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
1.7 10.4 GO:0030263 apoptotic chromosome condensation(GO:0030263)
1.7 5.2 GO:0010360 negative regulation of anion channel activity(GO:0010360)
1.7 1.7 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
1.7 5.2 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
1.7 5.1 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
1.7 10.2 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
1.7 6.8 GO:0045358 germ-line stem cell population maintenance(GO:0030718) negative regulation of interferon-beta biosynthetic process(GO:0045358)
1.7 5.0 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.7 5.0 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
1.6 16.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
1.6 8.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
1.6 9.8 GO:1990928 response to amino acid starvation(GO:1990928)
1.6 6.5 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
1.6 6.5 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
1.6 3.2 GO:0048496 maintenance of organ identity(GO:0048496)
1.6 7.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
1.6 15.7 GO:0071763 nuclear membrane organization(GO:0071763)
1.5 4.6 GO:0045204 MAPK export from nucleus(GO:0045204)
1.5 7.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
1.5 6.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
1.5 6.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
1.5 5.9 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
1.5 10.3 GO:0033484 nitric oxide homeostasis(GO:0033484)
1.5 8.8 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
1.5 5.9 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.4 4.3 GO:0043622 cortical microtubule organization(GO:0043622)
1.4 13.0 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
1.4 10.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.4 4.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.4 4.2 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
1.4 9.8 GO:0090169 regulation of spindle assembly(GO:0090169) regulation of mitotic spindle assembly(GO:1901673)
1.4 14.0 GO:0031053 primary miRNA processing(GO:0031053)
1.4 14.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
1.4 4.2 GO:0048254 snoRNA localization(GO:0048254)
1.4 16.6 GO:0002329 pre-B cell differentiation(GO:0002329)
1.3 9.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
1.3 9.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
1.3 6.5 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
1.3 7.8 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
1.3 5.0 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
1.3 6.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
1.3 7.5 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.2 6.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.2 22.3 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
1.2 7.4 GO:0021631 optic nerve morphogenesis(GO:0021631) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
1.2 4.9 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
1.2 3.6 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
1.2 3.6 GO:0006407 rRNA export from nucleus(GO:0006407)
1.2 13.2 GO:0000920 cell separation after cytokinesis(GO:0000920)
1.2 3.6 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
1.2 7.0 GO:0060008 Sertoli cell differentiation(GO:0060008)
1.2 3.5 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
1.1 3.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
1.1 12.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
1.1 12.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
1.1 5.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
1.1 5.6 GO:0061198 fungiform papilla development(GO:0061196) fungiform papilla morphogenesis(GO:0061197) fungiform papilla formation(GO:0061198)
1.1 10.1 GO:0001711 endodermal cell fate commitment(GO:0001711)
1.1 28.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
1.1 9.9 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
1.1 7.7 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
1.1 4.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
1.1 6.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.1 7.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
1.1 4.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.1 14.1 GO:0070914 UV-damage excision repair(GO:0070914)
1.1 20.6 GO:0042119 neutrophil activation(GO:0042119)
1.1 1.1 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
1.0 6.2 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
1.0 12.1 GO:0060363 cranial suture morphogenesis(GO:0060363)
1.0 7.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
1.0 7.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.0 4.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
1.0 8.0 GO:0015074 DNA integration(GO:0015074)
1.0 10.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
1.0 2.0 GO:0009838 abscission(GO:0009838)
1.0 4.9 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
1.0 7.9 GO:1902065 response to L-glutamate(GO:1902065)
1.0 3.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.0 8.6 GO:1990403 embryonic brain development(GO:1990403)
1.0 3.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.9 38.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.9 9.3 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.9 5.5 GO:0019985 translesion synthesis(GO:0019985)
0.9 9.1 GO:1900086 regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.9 5.4 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.9 4.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.9 24.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.9 1.7 GO:0045005 DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.8 18.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.8 6.5 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.8 19.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.8 4.9 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.8 2.4 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.8 4.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.8 7.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.8 0.8 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375)
0.8 6.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.8 3.1 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.8 3.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.8 3.8 GO:0014029 neural crest formation(GO:0014029)
0.7 13.5 GO:0015693 magnesium ion transport(GO:0015693)
0.7 11.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.7 15.6 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.7 2.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.7 5.2 GO:0006551 leucine metabolic process(GO:0006551)
0.7 4.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.7 16.0 GO:0031297 replication fork processing(GO:0031297)
0.7 2.9 GO:0043486 histone exchange(GO:0043486)
0.7 8.0 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.7 2.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.7 17.3 GO:0044783 mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783)
0.7 3.6 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.7 2.8 GO:0042373 vitamin K metabolic process(GO:0042373)
0.7 9.0 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.7 2.1 GO:0003162 atrioventricular node development(GO:0003162)
0.7 6.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.7 3.4 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.7 2.0 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.7 3.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.7 5.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.6 1.9 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.6 6.5 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.6 4.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.6 12.0 GO:0007099 centriole replication(GO:0007099)
0.6 1.9 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.6 11.1 GO:2000641 regulation of early endosome to late endosome transport(GO:2000641)
0.6 8.6 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.6 9.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.6 5.4 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.6 5.4 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.6 3.0 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.6 8.9 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.6 11.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.6 6.4 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.6 8.7 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.6 11.0 GO:0034508 centromere complex assembly(GO:0034508)
0.6 8.5 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.6 3.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.6 2.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.6 5.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.6 24.7 GO:0017145 stem cell division(GO:0017145)
0.6 1.7 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.6 5.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.6 2.2 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.5 2.2 GO:0071105 response to interleukin-11(GO:0071105) osteoclast fusion(GO:0072675)
0.5 5.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.5 3.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.5 2.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.5 11.7 GO:0034453 microtubule anchoring(GO:0034453)
0.5 2.7 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.5 3.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.5 12.1 GO:0050684 regulation of mRNA processing(GO:0050684)
0.5 1.6 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.5 1.6 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.5 4.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.5 7.5 GO:0006907 pinocytosis(GO:0006907)
0.5 6.0 GO:0036120 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.5 12.9 GO:0045841 negative regulation of mitotic metaphase/anaphase transition(GO:0045841) negative regulation of metaphase/anaphase transition of cell cycle(GO:1902100)
0.5 15.8 GO:0031648 protein destabilization(GO:0031648)
0.5 8.4 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.5 5.8 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.5 3.9 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.5 12.2 GO:0006379 mRNA cleavage(GO:0006379)
0.5 1.9 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.5 4.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.5 1.8 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.5 0.5 GO:0035844 positive regulation of polarized epithelial cell differentiation(GO:0030862) cloaca development(GO:0035844)
0.5 8.1 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.4 1.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 20.7 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.4 15.4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.4 0.9 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
0.4 1.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.4 10.5 GO:0010955 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.4 10.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.4 4.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.4 4.6 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.4 4.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.4 0.4 GO:0061738 late endosomal microautophagy(GO:0061738)
0.4 3.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.4 3.2 GO:0039529 RIG-I signaling pathway(GO:0039529)
0.4 6.7 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.4 6.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.4 8.3 GO:0060746 parental behavior(GO:0060746)
0.4 6.7 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.4 4.3 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.4 2.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.4 2.3 GO:0030913 paranodal junction assembly(GO:0030913)
0.4 7.6 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.4 5.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.4 6.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.4 3.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.4 2.6 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.4 1.8 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.4 1.1 GO:0045006 DNA deamination(GO:0045006)
0.4 2.9 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.4 1.8 GO:0006868 glutamine transport(GO:0006868)
0.4 3.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.4 1.1 GO:0016246 RNA interference(GO:0016246)
0.4 2.8 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.4 3.2 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.4 1.4 GO:0033762 response to glucagon(GO:0033762)
0.4 6.0 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.3 5.2 GO:0048520 positive regulation of behavior(GO:0048520)
0.3 37.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.3 10.6 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.3 1.0 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.3 16.8 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.3 23.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.3 3.9 GO:0001779 natural killer cell differentiation(GO:0001779)
0.3 2.9 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.3 4.9 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.3 1.6 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.3 3.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.3 1.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.3 3.4 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.3 0.9 GO:0016598 protein arginylation(GO:0016598)
0.3 0.6 GO:1904798 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.3 1.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.3 0.6 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.3 11.4 GO:0007492 endoderm development(GO:0007492)
0.3 0.6 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.3 7.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.3 4.4 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.3 1.4 GO:0008343 adult feeding behavior(GO:0008343)
0.3 4.3 GO:0032366 intracellular lipid transport(GO:0032365) intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.3 0.6 GO:0032056 positive regulation of translation in response to stress(GO:0032056)
0.3 14.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.3 1.7 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.3 4.0 GO:0044030 regulation of DNA methylation(GO:0044030)
0.3 0.5 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.3 6.2 GO:0007020 microtubule nucleation(GO:0007020)
0.3 1.6 GO:0048102 autophagic cell death(GO:0048102)
0.3 1.6 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.3 0.8 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 8.1 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.3 3.1 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.3 8.4 GO:0007520 myoblast fusion(GO:0007520)
0.3 2.0 GO:0006817 phosphate ion transport(GO:0006817)
0.3 1.8 GO:0010869 regulation of receptor biosynthetic process(GO:0010869)
0.2 2.0 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 1.5 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.2 2.6 GO:0006366 transcription from RNA polymerase II promoter(GO:0006366)
0.2 30.9 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.2 2.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 8.2 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 4.0 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.2 3.5 GO:0031167 rRNA methylation(GO:0031167)
0.2 9.8 GO:1902017 regulation of cilium assembly(GO:1902017)
0.2 0.5 GO:0097212 lysosomal membrane organization(GO:0097212)
0.2 2.9 GO:0043277 apoptotic cell clearance(GO:0043277)
0.2 5.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.2 0.9 GO:1902592 viral budding(GO:0046755) multivesicular body sorting pathway(GO:0071985) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.2 1.3 GO:0009301 snRNA transcription(GO:0009301)
0.2 1.1 GO:0002121 inter-male aggressive behavior(GO:0002121) response to pheromone(GO:0019236)
0.2 6.6 GO:0016579 protein deubiquitination(GO:0016579)
0.2 5.9 GO:0018345 protein palmitoylation(GO:0018345)
0.2 6.9 GO:0048661 positive regulation of smooth muscle cell proliferation(GO:0048661)
0.2 4.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.2 2.9 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.2 3.1 GO:0048266 behavioral response to pain(GO:0048266)
0.2 0.2 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.2 1.9 GO:0035148 embryonic epithelial tube formation(GO:0001838) neural tube formation(GO:0001841) tube formation(GO:0035148) epithelial tube formation(GO:0072175)
0.2 0.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2 4.1 GO:0000910 cytokinesis(GO:0000910)
0.2 0.9 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 10.9 GO:0007631 feeding behavior(GO:0007631)
0.2 1.7 GO:0000729 DNA double-strand break processing(GO:0000729)
0.2 1.8 GO:0002176 male germ cell proliferation(GO:0002176)
0.2 4.2 GO:0007059 chromosome segregation(GO:0007059)
0.2 2.0 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.2 0.5 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.2 11.0 GO:0046847 filopodium assembly(GO:0046847)
0.2 48.4 GO:0006397 mRNA processing(GO:0006397)
0.2 3.4 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.2 2.8 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.2 2.7 GO:0032801 receptor catabolic process(GO:0032801)
0.2 1.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.2 3.5 GO:0003170 heart valve development(GO:0003170)
0.2 0.7 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.2 1.0 GO:0048863 stem cell differentiation(GO:0048863)
0.2 11.7 GO:0007030 Golgi organization(GO:0007030)
0.2 2.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.2 3.9 GO:0071897 DNA biosynthetic process(GO:0071897)
0.2 0.3 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.2 0.6 GO:0045176 apical protein localization(GO:0045176)
0.2 0.9 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 0.5 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.2 4.1 GO:0010259 multicellular organism aging(GO:0010259)
0.2 4.0 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 4.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.1 1.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.7 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.1 1.6 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 2.1 GO:0051642 centrosome localization(GO:0051642)
0.1 2.0 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 2.0 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.1 0.7 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 1.2 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 1.2 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.1 0.2 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host cell(GO:0044650) complement-dependent cytotoxicity(GO:0097278)
0.1 1.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.1 0.8 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.7 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 2.9 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 2.4 GO:0001935 endothelial cell proliferation(GO:0001935)
0.1 0.4 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 3.5 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 7.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 1.9 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.1 0.9 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 2.2 GO:1901998 toxin transport(GO:1901998)
0.1 0.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 1.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 9.2 GO:0007276 gamete generation(GO:0007276)
0.1 0.2 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.3 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 1.3 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 7.7 GO:0006275 regulation of DNA replication(GO:0006275)
0.1 0.2 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.2 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 5.7 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 1.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 1.7 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 1.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.6 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 2.3 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.1 1.9 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.1 1.2 GO:0003016 respiratory system process(GO:0003016)
0.1 0.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.4 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.1 0.6 GO:0034204 lipid translocation(GO:0034204)
0.1 0.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.4 GO:0043278 response to morphine(GO:0043278)
0.0 0.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 1.1 GO:0001934 positive regulation of protein phosphorylation(GO:0001934)
0.0 3.9 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 1.4 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.9 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.1 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 1.9 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.6 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.4 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.8 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.9 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.6 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 6.8 GO:0030334 regulation of cell migration(GO:0030334)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.7 GO:0006826 iron ion transport(GO:0006826)
0.0 0.1 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.0 0.8 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 1.4 GO:0008360 regulation of cell shape(GO:0008360)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 23.4 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
7.5 29.9 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
6.1 61.1 GO:0000796 condensin complex(GO:0000796)
5.1 30.8 GO:0098536 deuterosome(GO:0098536)
5.0 20.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
4.8 19.3 GO:0044307 dendritic branch(GO:0044307)
4.3 8.6 GO:0042585 germinal vesicle(GO:0042585)
4.2 12.7 GO:0005940 septin ring(GO:0005940)
3.8 26.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
3.5 17.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
3.3 9.8 GO:0031372 UBC13-MMS2 complex(GO:0031372)
3.3 13.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
3.2 16.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
3.0 11.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
2.9 8.8 GO:1990047 spindle matrix(GO:1990047)
2.6 21.2 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
2.6 10.4 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
2.6 12.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
2.6 25.5 GO:0000805 X chromosome(GO:0000805)
2.5 12.7 GO:0000798 nuclear cohesin complex(GO:0000798)
2.5 7.6 GO:0035061 interchromatin granule(GO:0035061)
2.3 11.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
2.2 8.8 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
2.1 2.1 GO:0098830 presynaptic endosome(GO:0098830)
2.1 14.9 GO:0001940 male pronucleus(GO:0001940)
2.1 12.5 GO:0097227 sperm annulus(GO:0097227)
2.1 18.8 GO:0097165 nuclear stress granule(GO:0097165)
2.0 8.1 GO:0070552 BRISC complex(GO:0070552)
2.0 18.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
2.0 17.9 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
1.9 39.0 GO:0035253 ciliary rootlet(GO:0035253)
1.8 7.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
1.8 5.4 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
1.8 30.3 GO:0097431 mitotic spindle pole(GO:0097431)
1.7 13.9 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
1.7 7.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
1.7 19.0 GO:0005641 nuclear envelope lumen(GO:0005641)
1.7 10.2 GO:0031010 ISWI-type complex(GO:0031010)
1.7 11.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.6 9.7 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.6 9.4 GO:0000444 MIS12/MIND type complex(GO:0000444)
1.5 12.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
1.5 12.1 GO:0042382 paraspeckles(GO:0042382)
1.5 15.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
1.5 4.5 GO:0030905 retromer, tubulation complex(GO:0030905)
1.4 18.8 GO:1990635 proximal dendrite(GO:1990635)
1.4 14.4 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
1.4 28.7 GO:0016580 Sin3 complex(GO:0016580)
1.4 4.1 GO:0070939 Dsl1p complex(GO:0070939)
1.4 1.4 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
1.4 4.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
1.3 10.6 GO:0046581 intercellular canaliculus(GO:0046581)
1.3 7.8 GO:0044615 nuclear pore nuclear basket(GO:0044615)
1.3 7.7 GO:0097513 myosin II filament(GO:0097513)
1.3 3.8 GO:0001939 female pronucleus(GO:0001939)
1.3 11.5 GO:0002177 manchette(GO:0002177)
1.3 2.6 GO:0070820 tertiary granule(GO:0070820)
1.3 3.8 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
1.2 10.6 GO:0071141 SMAD protein complex(GO:0071141)
1.2 5.8 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
1.1 4.6 GO:0032021 NELF complex(GO:0032021)
1.1 11.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
1.1 5.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
1.1 6.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
1.1 31.7 GO:0030992 intraciliary transport particle B(GO:0030992)
1.0 20.9 GO:0000242 pericentriolar material(GO:0000242)
1.0 1.0 GO:0071942 XPC complex(GO:0071942)
1.0 8.2 GO:0031415 NatA complex(GO:0031415)
1.0 7.2 GO:0044666 MLL3/4 complex(GO:0044666)
1.0 3.0 GO:0035102 PRC1 complex(GO:0035102)
1.0 11.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
1.0 21.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.0 19.8 GO:0071004 U2-type prespliceosome(GO:0071004)
1.0 7.8 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
1.0 1.9 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.9 6.5 GO:0070187 telosome(GO:0070187)
0.9 4.5 GO:0072487 MSL complex(GO:0072487)
0.9 4.3 GO:0000235 astral microtubule(GO:0000235)
0.9 11.1 GO:0005686 U2 snRNP(GO:0005686)
0.8 8.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.8 8.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.8 5.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.8 44.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.8 7.9 GO:0001741 XY body(GO:0001741)
0.8 26.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.8 3.9 GO:0044611 nuclear pore inner ring(GO:0044611)
0.8 9.8 GO:0097539 ciliary transition fiber(GO:0097539)
0.8 6.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.7 5.2 GO:0071203 WASH complex(GO:0071203)
0.7 3.7 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.7 3.6 GO:0030314 junctional membrane complex(GO:0030314)
0.7 5.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.7 7.2 GO:0031011 Ino80 complex(GO:0031011)
0.6 1.9 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.6 1.9 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.6 11.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.6 6.7 GO:0042405 nuclear inclusion body(GO:0042405)
0.6 5.4 GO:0030478 actin cap(GO:0030478)
0.6 10.2 GO:0051286 cell tip(GO:0051286)
0.6 4.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.6 2.4 GO:0000974 Prp19 complex(GO:0000974)
0.6 7.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.6 4.6 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.6 8.5 GO:0017119 Golgi transport complex(GO:0017119)
0.5 1.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.5 8.6 GO:1904115 axon cytoplasm(GO:1904115)
0.5 10.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.5 40.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.5 7.8 GO:0032039 integrator complex(GO:0032039)
0.5 3.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.5 3.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.5 5.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.5 6.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.5 16.9 GO:0005876 spindle microtubule(GO:0005876)
0.5 10.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.5 6.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.4 2.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.4 1.8 GO:0001652 granular component(GO:0001652)
0.4 19.3 GO:0005871 kinesin complex(GO:0005871)
0.4 7.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.4 4.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.4 4.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 7.6 GO:0035371 microtubule plus-end(GO:0035371)
0.4 2.0 GO:0090543 Flemming body(GO:0090543)
0.4 24.4 GO:0000922 spindle pole(GO:0000922)
0.4 3.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.4 3.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 11.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.3 10.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 51.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.3 10.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.3 1.7 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.3 5.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 10.4 GO:0000791 euchromatin(GO:0000791)
0.3 4.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3 8.8 GO:0044815 DNA packaging complex(GO:0044815)
0.3 4.5 GO:0035861 site of double-strand break(GO:0035861)
0.3 2.6 GO:0000813 ESCRT I complex(GO:0000813)
0.3 16.0 GO:0005814 centriole(GO:0005814)
0.3 8.2 GO:0033268 node of Ranvier(GO:0033268)
0.3 1.2 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.3 1.7 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.3 3.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3 22.8 GO:0016605 PML body(GO:0016605)
0.3 1.7 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.3 1.9 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.3 2.5 GO:0061700 GATOR2 complex(GO:0061700)
0.3 15.5 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.3 24.7 GO:0005681 spliceosomal complex(GO:0005681)
0.3 2.2 GO:0034702 ion channel complex(GO:0034702)
0.3 13.6 GO:0000502 proteasome complex(GO:0000502)
0.2 9.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 1.5 GO:0005955 calcineurin complex(GO:0005955)
0.2 1.4 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 2.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 13.8 GO:0000793 condensed chromosome(GO:0000793)
0.2 3.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 74.4 GO:0000785 chromatin(GO:0000785)
0.2 3.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 5.6 GO:0043596 nuclear replication fork(GO:0043596)
0.2 11.5 GO:0005811 lipid particle(GO:0005811)
0.2 0.6 GO:0031417 NatC complex(GO:0031417)
0.2 1.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 15.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 11.3 GO:0016459 myosin complex(GO:0016459)
0.2 1.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 2.8 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.2 83.6 GO:0016604 nuclear body(GO:0016604)
0.2 1.0 GO:0000346 transcription export complex(GO:0000346)
0.2 6.6 GO:0043034 costamere(GO:0043034)
0.2 33.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.2 1.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 6.3 GO:0060077 inhibitory synapse(GO:0060077)
0.2 6.2 GO:0034707 chloride channel complex(GO:0034707)
0.2 2.6 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.2 1.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.2 6.1 GO:0031941 filamentous actin(GO:0031941)
0.2 3.6 GO:0097546 ciliary base(GO:0097546)
0.2 1.5 GO:0005915 zonula adherens(GO:0005915)
0.2 8.1 GO:0005643 nuclear pore(GO:0005643)
0.2 33.9 GO:0005815 microtubule organizing center(GO:0005815)
0.2 3.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 2.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 1.7 GO:0031209 SCAR complex(GO:0031209)
0.1 18.0 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.7 GO:0030133 transport vesicle(GO:0030133)
0.1 0.8 GO:0070847 core mediator complex(GO:0070847)
0.1 9.8 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 8.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 20.8 GO:0031965 nuclear membrane(GO:0031965)
0.1 10.7 GO:0030027 lamellipodium(GO:0030027)
0.1 3.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.3 GO:0031932 TORC2 complex(GO:0031932)
0.1 3.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 5.3 GO:0031985 Golgi cisterna(GO:0031985)
0.1 3.9 GO:0036064 ciliary basal body(GO:0036064)
0.1 1.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 4.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 16.7 GO:0044306 neuron projection terminus(GO:0044306)
0.1 14.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 7.2 GO:0072562 blood microparticle(GO:0072562)
0.1 11.0 GO:0015629 actin cytoskeleton(GO:0015629)
0.1 3.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 10.7 GO:0030426 growth cone(GO:0030426)
0.1 3.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 12.0 GO:0005874 microtubule(GO:0005874)
0.1 5.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 6.5 GO:0005694 chromosome(GO:0005694)
0.1 6.5 GO:0001650 fibrillar center(GO:0001650)
0.1 1.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 87.0 GO:0005654 nucleoplasm(GO:0005654)
0.1 1.2 GO:0032590 dendrite membrane(GO:0032590)
0.1 4.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 2.4 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 7.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 13.2 GO:0005768 endosome(GO:0005768)
0.0 1.2 GO:0043292 contractile fiber(GO:0043292)
0.0 0.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 5.5 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 55.8 GO:0001069 regulatory region RNA binding(GO:0001069)
7.4 22.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
6.1 18.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
5.9 23.4 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
4.9 34.1 GO:0099609 microtubule lateral binding(GO:0099609)
4.8 33.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
4.6 13.9 GO:0031871 proteinase activated receptor binding(GO:0031871)
4.5 26.8 GO:0097016 L27 domain binding(GO:0097016)
4.3 29.9 GO:0015616 DNA translocase activity(GO:0015616)
4.1 16.5 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
4.0 20.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
3.6 25.4 GO:0033592 RNA strand annealing activity(GO:0033592)
3.5 10.6 GO:0035500 MH2 domain binding(GO:0035500)
3.3 16.7 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
3.1 9.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
2.9 11.6 GO:0036033 mediator complex binding(GO:0036033)
2.9 17.4 GO:0097001 ceramide binding(GO:0097001)
2.7 13.7 GO:0035174 histone serine kinase activity(GO:0035174)
2.6 33.9 GO:0016929 SUMO-specific protease activity(GO:0016929)
2.5 7.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
2.4 7.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
2.3 7.0 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
2.3 2.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
2.1 8.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
2.0 14.2 GO:0061665 SUMO ligase activity(GO:0061665)
2.0 20.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
1.9 15.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
1.9 7.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.9 15.0 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
1.9 5.6 GO:0071568 UFM1 transferase activity(GO:0071568)
1.9 11.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
1.8 12.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
1.8 20.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
1.8 11.0 GO:0044547 DNA topoisomerase binding(GO:0044547)
1.8 3.6 GO:0001083 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083)
1.8 5.4 GO:0034190 apolipoprotein receptor binding(GO:0034190)
1.7 38.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
1.7 6.8 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
1.5 7.5 GO:0050786 RAGE receptor binding(GO:0050786)
1.5 10.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
1.5 4.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
1.5 7.3 GO:0034046 poly(G) binding(GO:0034046)
1.4 14.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.4 6.8 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
1.4 13.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
1.4 8.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
1.3 2.7 GO:0071987 WD40-repeat domain binding(GO:0071987)
1.3 9.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.3 11.9 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
1.3 7.8 GO:0071532 ankyrin repeat binding(GO:0071532)
1.3 3.8 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
1.3 5.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.3 10.2 GO:0030911 TPR domain binding(GO:0030911)
1.3 15.2 GO:0044548 S100 protein binding(GO:0044548)
1.3 11.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.2 7.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.2 9.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
1.2 6.0 GO:0034452 dynactin binding(GO:0034452)
1.2 3.6 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
1.2 5.8 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.1 3.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
1.1 21.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
1.1 9.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.1 2.3 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
1.1 4.5 GO:1990460 leptin receptor binding(GO:1990460)
1.1 5.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
1.1 4.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
1.1 4.3 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
1.1 39.4 GO:0017091 AU-rich element binding(GO:0017091)
1.1 6.3 GO:0070728 leucine binding(GO:0070728)
1.1 8.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
1.0 29.6 GO:0070840 dynein complex binding(GO:0070840)
1.0 6.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
1.0 4.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
1.0 3.9 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
1.0 2.9 GO:0031752 D5 dopamine receptor binding(GO:0031752)
1.0 1.9 GO:0043522 leucine zipper domain binding(GO:0043522)
1.0 14.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
1.0 4.8 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.9 3.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.9 46.9 GO:0070063 RNA polymerase binding(GO:0070063)
0.9 5.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.8 5.9 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.8 42.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.8 5.0 GO:0033142 progesterone receptor binding(GO:0033142)
0.8 16.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.8 3.9 GO:0008172 S-methyltransferase activity(GO:0008172)
0.8 17.0 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.8 15.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.8 7.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.8 51.4 GO:0034212 peptide N-acetyltransferase activity(GO:0034212)
0.8 1.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.8 13.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.8 8.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.7 24.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.7 13.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.7 4.2 GO:0045545 syndecan binding(GO:0045545)
0.7 2.0 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.7 3.3 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.7 53.8 GO:0003777 microtubule motor activity(GO:0003777)
0.6 6.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.6 22.9 GO:0030331 estrogen receptor binding(GO:0030331)
0.6 30.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.6 3.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.6 1.9 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.6 10.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.6 11.4 GO:0070717 poly-purine tract binding(GO:0070717)
0.6 24.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.6 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.6 12.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.6 12.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.6 0.6 GO:0019003 GDP binding(GO:0019003)
0.6 16.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.6 1.7 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.5 6.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.5 0.5 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.5 10.6 GO:0070410 co-SMAD binding(GO:0070410)
0.5 12.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.5 13.6 GO:0070064 proline-rich region binding(GO:0070064)
0.5 1.6 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.5 4.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.5 15.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.5 7.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.5 9.0 GO:0005521 lamin binding(GO:0005521)
0.5 4.0 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.5 3.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.5 6.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.5 14.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.5 14.8 GO:0051018 protein kinase A binding(GO:0051018)
0.5 5.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.5 1.8 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.4 10.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.4 12.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.4 21.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.4 14.4 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.4 42.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.4 2.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.4 3.8 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.4 3.8 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.4 1.7 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.4 5.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.4 10.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.4 1.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.4 1.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.4 6.7 GO:0070402 NADPH binding(GO:0070402)
0.4 1.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.4 7.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.4 9.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.4 29.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.4 4.1 GO:0004659 prenyltransferase activity(GO:0004659)
0.4 11.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.4 3.6 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.4 3.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.3 4.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.3 6.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 92.6 GO:0061659 ubiquitin-like protein ligase activity(GO:0061659)
0.3 3.3 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.3 6.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.3 1.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.3 2.3 GO:1990405 protein antigen binding(GO:1990405)
0.3 6.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 4.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.3 57.9 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.3 11.3 GO:0003774 motor activity(GO:0003774)
0.3 5.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.3 13.6 GO:0035064 methylated histone binding(GO:0035064)
0.3 1.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.3 20.5 GO:0032947 protein complex scaffold(GO:0032947)
0.3 8.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.3 119.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.3 3.7 GO:0031005 filamin binding(GO:0031005)
0.3 1.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.3 5.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 9.7 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.2 2.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.2 3.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 5.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 1.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 7.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 5.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 3.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 43.0 GO:0008017 microtubule binding(GO:0008017)
0.2 3.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 5.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 2.0 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 90.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.2 4.2 GO:0008483 transaminase activity(GO:0008483)
0.2 1.0 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 3.5 GO:0031402 sodium ion binding(GO:0031402)
0.2 3.4 GO:0003684 damaged DNA binding(GO:0003684)
0.2 1.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 6.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 14.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 6.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 2.0 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.2 2.8 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.2 1.6 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.2 2.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 10.1 GO:0043130 ubiquitin binding(GO:0043130)
0.2 0.8 GO:0051400 BH domain binding(GO:0051400)
0.2 0.9 GO:0070513 death domain binding(GO:0070513)
0.2 2.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 2.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 1.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 0.5 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.2 1.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 4.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 5.2 GO:0005109 frizzled binding(GO:0005109)
0.1 1.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 10.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 99.6 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 3.5 GO:0008198 ferrous iron binding(GO:0008198)
0.1 1.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 5.0 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 1.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.8 GO:0071253 connexin binding(GO:0071253)
0.1 1.4 GO:0031489 myosin V binding(GO:0031489)
0.1 3.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 2.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 2.0 GO:0008276 protein methyltransferase activity(GO:0008276)
0.1 11.4 GO:0004386 helicase activity(GO:0004386)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 22.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 2.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 7.6 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 3.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 2.0 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.9 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 54.4 GO:0003677 DNA binding(GO:0003677)
0.1 2.1 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.2 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 1.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.9 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 2.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 1.8 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.1 12.3 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.1 5.6 GO:0005178 integrin binding(GO:0005178)
0.1 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 5.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 0.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 2.4 GO:0032934 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.1 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 1.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 3.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.8 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.1 GO:0051117 ATPase binding(GO:0051117)
0.0 1.1 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 2.9 GO:0005525 GTP binding(GO:0005525)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 107.9 PID_AURORA_B_PATHWAY Aurora B signaling
1.4 19.4 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
1.0 7.3 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
1.0 61.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.9 20.4 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.9 21.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.8 34.9 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.7 30.3 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.7 27.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.7 18.2 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.7 21.9 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.7 60.0 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.7 25.1 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.7 17.0 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.6 5.7 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.6 9.0 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.5 28.7 PID_PLK1_PATHWAY PLK1 signaling events
0.4 16.7 PID_ATM_PATHWAY ATM pathway
0.4 18.3 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.4 4.5 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.4 15.0 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.4 2.9 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.3 6.2 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 7.7 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3 6.1 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.3 7.1 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.2 5.9 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.2 4.4 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.2 1.2 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.2 5.8 PID_RAS_PATHWAY Regulation of Ras family activation
0.2 10.7 PID_E2F_PATHWAY E2F transcription factor network
0.2 3.1 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 4.1 PID_CDC42_PATHWAY CDC42 signaling events
0.1 5.7 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 3.1 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 4.3 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 1.8 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 2.3 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 3.5 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 3.6 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.1 4.6 PID_TNF_PATHWAY TNF receptor signaling pathway
0.1 2.3 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 1.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 17.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 4.7 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 3.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.5 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 1.3 SIG_CHEMOTAXIS Genes related to chemotaxis
0.1 1.8 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.1 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.7 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.6 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 4.0 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.9 PID_FGF_PATHWAY FGF signaling pathway
0.0 3.2 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 1.2 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 8.6 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
2.9 2.9 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
2.7 73.0 REACTOME_KINESINS Genes involved in Kinesins
1.8 99.5 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.7 29.7 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.6 47.8 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
1.5 21.1 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.4 24.2 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
1.3 69.7 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
1.3 54.8 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
1.3 7.5 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
1.2 4.7 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
1.1 10.1 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.0 31.9 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.9 10.9 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.8 5.9 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.8 11.7 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.8 34.1 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.8 14.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.7 28.6 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.7 17.6 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.6 6.2 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.6 13.6 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.6 10.1 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.5 15.9 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.5 7.0 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.5 9.6 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.5 8.5 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.5 46.3 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.5 36.2 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.5 14.9 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.4 8.5 REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.4 9.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.4 3.5 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.4 6.9 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.4 12.4 REACTOME_G1_PHASE Genes involved in G1 Phase
0.4 5.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4 9.3 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.4 4.6 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.3 14.1 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 4.8 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.3 18.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 1.9 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 2.6 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.3 7.1 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.3 6.4 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.3 9.8 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.3 4.0 REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.3 3.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 7.7 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.3 1.6 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.3 0.8 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 8.2 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 7.5 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 1.9 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.2 7.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.2 12.7 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.2 2.8 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 3.1 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 5.8 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 13.1 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 6.0 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 3.8 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.2 6.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.2 2.5 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.2 4.3 REACTOME_AMYLOIDS Genes involved in Amyloids
0.2 2.8 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.2 2.6 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.2 6.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 2.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 4.0 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 3.0 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.1 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.5 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.0 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.0 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 3.2 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.1 8.6 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 0.9 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.4 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.1 REACTOME_CD28_CO_STIMULATION Genes involved in CD28 co-stimulation
0.1 5.4 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 0.7 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 1.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 1.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.1 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.4 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 4.6 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.6 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 2.1 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.6 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 0.6 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 2.6 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.3 REACTOME_DNA_REPAIR Genes involved in DNA Repair
0.0 0.1 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 3.1 REACTOME_GLUCOSE_METABOLISM Genes involved in Glucose metabolism
0.0 1.5 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.9 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 4.7 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine