Motif ID: Tbx15
Z-value: 0.768
Transcription factors associated with Tbx15:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Tbx15 | ENSMUSG00000027868.5 | Tbx15 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 20.6 | GO:0032763 | regulation of mast cell cytokine production(GO:0032763) |
| 3.3 | 6.5 | GO:0098917 | retrograde trans-synaptic signaling(GO:0098917) |
| 3.0 | 9.0 | GO:0099548 | trans-synaptic signaling by nitric oxide(GO:0099548) |
| 2.5 | 7.4 | GO:0001928 | regulation of exocyst assembly(GO:0001928) |
| 2.4 | 7.2 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
| 2.4 | 7.1 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 2.3 | 6.8 | GO:0048687 | positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) |
| 2.0 | 6.1 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 2.0 | 22.4 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 1.9 | 5.7 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 1.9 | 5.7 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 1.6 | 9.9 | GO:0042045 | epithelial fluid transport(GO:0042045) |
| 1.6 | 6.3 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 1.5 | 6.1 | GO:0008078 | mesodermal cell migration(GO:0008078) |
| 1.4 | 4.2 | GO:0009826 | unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 1.3 | 5.3 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
| 1.3 | 3.8 | GO:0002182 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
| 1.2 | 3.7 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
| 1.1 | 4.5 | GO:0051866 | general adaptation syndrome(GO:0051866) |
| 1.0 | 3.1 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.9 | 3.7 | GO:2000304 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
| 0.9 | 5.4 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.9 | 2.6 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.8 | 3.4 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 0.8 | 2.5 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
| 0.8 | 4.0 | GO:0002158 | osteoclast proliferation(GO:0002158) |
| 0.7 | 2.2 | GO:1902277 | negative regulation of pancreatic amylase secretion(GO:1902277) |
| 0.7 | 2.2 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
| 0.7 | 2.2 | GO:0015747 | urate transport(GO:0015747) |
| 0.7 | 3.6 | GO:0015867 | ATP transport(GO:0015867) |
| 0.6 | 2.5 | GO:1903764 | regulation of potassium ion export across plasma membrane(GO:1903764) |
| 0.6 | 1.8 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.6 | 2.3 | GO:0044268 | multicellular organismal protein metabolic process(GO:0044268) |
| 0.6 | 2.8 | GO:0015871 | choline transport(GO:0015871) |
| 0.5 | 1.5 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.5 | 2.8 | GO:0035166 | post-embryonic hemopoiesis(GO:0035166) |
| 0.5 | 2.7 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.4 | 4.0 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.4 | 3.0 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.4 | 1.7 | GO:0032275 | luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278) |
| 0.4 | 7.7 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.4 | 0.7 | GO:0031394 | positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
| 0.4 | 5.0 | GO:0097119 | postsynaptic density protein 95 clustering(GO:0097119) |
| 0.4 | 2.1 | GO:0072396 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) |
| 0.4 | 0.7 | GO:0045054 | constitutive secretory pathway(GO:0045054) |
| 0.3 | 1.0 | GO:0035799 | ureter maturation(GO:0035799) |
| 0.3 | 1.0 | GO:0031335 | regulation of sulfur amino acid metabolic process(GO:0031335) |
| 0.3 | 8.6 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.3 | 4.9 | GO:0015809 | arginine transport(GO:0015809) |
| 0.3 | 2.3 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 0.3 | 1.3 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.3 | 1.5 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.3 | 3.4 | GO:0014052 | regulation of gamma-aminobutyric acid secretion(GO:0014052) |
| 0.3 | 1.5 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.3 | 2.7 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.3 | 1.7 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
| 0.3 | 1.1 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
| 0.3 | 0.8 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
| 0.3 | 1.1 | GO:0071726 | response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) |
| 0.3 | 0.8 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
| 0.3 | 0.8 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) |
| 0.3 | 0.8 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627) |
| 0.2 | 0.7 | GO:0046416 | D-amino acid metabolic process(GO:0046416) |
| 0.2 | 3.0 | GO:0007141 | male meiosis I(GO:0007141) |
| 0.2 | 3.2 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.2 | 0.7 | GO:2001160 | regulation of histone H3-K79 methylation(GO:2001160) |
| 0.2 | 1.1 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.2 | 1.1 | GO:0010626 | negative regulation of Schwann cell proliferation(GO:0010626) |
| 0.2 | 0.7 | GO:0006116 | NADH oxidation(GO:0006116) |
| 0.2 | 1.1 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 0.2 | 1.3 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
| 0.2 | 4.9 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.2 | 0.6 | GO:0051182 | coenzyme transport(GO:0051182) |
| 0.2 | 1.0 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.2 | 1.2 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
| 0.2 | 1.1 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 0.2 | 4.5 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.2 | 0.7 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.2 | 1.5 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.2 | 1.5 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 0.2 | 0.7 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.2 | 1.3 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.2 | 0.5 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
| 0.2 | 0.7 | GO:0060332 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) positive regulation of G0 to G1 transition(GO:0070318) |
| 0.2 | 2.1 | GO:0099628 | receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) regulation of grooming behavior(GO:2000821) |
| 0.2 | 0.5 | GO:0060431 | primary lung bud formation(GO:0060431) |
| 0.2 | 1.2 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.2 | 2.2 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.2 | 0.5 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.2 | 2.1 | GO:1901898 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.2 | 3.0 | GO:0051968 | positive regulation of synaptic transmission, glutamatergic(GO:0051968) |
| 0.2 | 6.8 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
| 0.2 | 0.5 | GO:0019043 | establishment of viral latency(GO:0019043) |
| 0.2 | 1.5 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.2 | 6.3 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
| 0.1 | 0.9 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.1 | 1.3 | GO:0019673 | GDP-mannose metabolic process(GO:0019673) |
| 0.1 | 2.1 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.1 | 2.4 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.1 | 1.8 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
| 0.1 | 0.4 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 0.1 | 3.9 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.1 | 0.4 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.1 | 0.8 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.1 | 0.9 | GO:0015961 | diadenosine polyphosphate catabolic process(GO:0015961) |
| 0.1 | 4.6 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.1 | 0.4 | GO:1904580 | regulation of polynucleotide adenylyltransferase activity(GO:1904245) regulation of intracellular mRNA localization(GO:1904580) |
| 0.1 | 0.3 | GO:0097026 | dendritic cell dendrite assembly(GO:0097026) |
| 0.1 | 0.5 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.1 | 0.6 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
| 0.1 | 1.1 | GO:0030953 | astral microtubule organization(GO:0030953) |
| 0.1 | 0.6 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
| 0.1 | 0.5 | GO:0090669 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669) |
| 0.1 | 3.3 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
| 0.1 | 0.7 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.1 | 0.8 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.1 | 0.4 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.1 | 1.5 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
| 0.1 | 0.5 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.1 | 2.9 | GO:0030517 | negative regulation of axon extension(GO:0030517) |
| 0.1 | 2.1 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
| 0.1 | 1.4 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.1 | 1.9 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.1 | 0.3 | GO:0038108 | negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) |
| 0.1 | 0.6 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.1 | 1.6 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.1 | 1.7 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.1 | 2.0 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.1 | 0.5 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
| 0.1 | 0.6 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.1 | 0.3 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.1 | 1.9 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.1 | 0.2 | GO:1901069 | guanosine-containing compound catabolic process(GO:1901069) |
| 0.1 | 0.1 | GO:0006533 | aspartate catabolic process(GO:0006533) |
| 0.0 | 1.1 | GO:0033006 | regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304) |
| 0.0 | 0.8 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.0 | 0.7 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 0.0 | 0.3 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.0 | 0.6 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
| 0.0 | 0.4 | GO:1903351 | response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351) |
| 0.0 | 0.1 | GO:1904154 | positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
| 0.0 | 2.2 | GO:0048168 | regulation of neuronal synaptic plasticity(GO:0048168) |
| 0.0 | 4.2 | GO:0051101 | regulation of DNA binding(GO:0051101) |
| 0.0 | 0.4 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 0.0 | 0.4 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.0 | 1.5 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 1.6 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 0.2 | GO:1901525 | negative regulation of macromitophagy(GO:1901525) |
| 0.0 | 0.6 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.0 | 0.4 | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) |
| 0.0 | 0.1 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.0 | 1.5 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.4 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.0 | 1.9 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.0 | 0.6 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 2.1 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.2 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
| 0.0 | 0.6 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.0 | 0.4 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.0 | 0.2 | GO:0042167 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.0 | 0.2 | GO:0098903 | regulation of membrane repolarization during action potential(GO:0098903) |
| 0.0 | 0.4 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 0.8 | GO:0051452 | intracellular pH reduction(GO:0051452) |
| 0.0 | 0.3 | GO:0090031 | positive regulation of steroid hormone biosynthetic process(GO:0090031) |
| 0.0 | 1.6 | GO:0001525 | angiogenesis(GO:0001525) |
| 0.0 | 0.2 | GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) |
| 0.0 | 0.2 | GO:0099500 | synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500) |
| 0.0 | 0.2 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.0 | 0.9 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.0 | 0.4 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.0 | 0.8 | GO:0035690 | cellular response to drug(GO:0035690) |
| 0.0 | 2.3 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 0.1 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
| 0.0 | 0.5 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
| 0.0 | 0.2 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) |
| 0.0 | 2.1 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.0 | 0.3 | GO:0042493 | response to drug(GO:0042493) |
| 0.0 | 0.1 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
| 0.0 | 0.2 | GO:0071459 | protein localization to chromosome, centromeric region(GO:0071459) |
| 0.0 | 0.2 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.0 | 0.2 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.0 | 0.0 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) |
| 0.0 | 0.1 | GO:0045792 | negative regulation of cell size(GO:0045792) |
| 0.0 | 0.8 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 0.1 | GO:0097502 | mannosylation(GO:0097502) |
| 0.0 | 1.6 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 1.5 | GO:0043062 | extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.3 | 9.9 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.9 | 33.1 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.8 | 3.8 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.7 | 3.7 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.7 | 0.7 | GO:0030128 | clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.7 | 2.8 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
| 0.7 | 10.7 | GO:0043196 | varicosity(GO:0043196) |
| 0.6 | 4.5 | GO:0071203 | WASH complex(GO:0071203) |
| 0.5 | 1.5 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.5 | 6.8 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.5 | 8.6 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.4 | 2.1 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
| 0.4 | 1.6 | GO:0030673 | axolemma(GO:0030673) |
| 0.4 | 1.5 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
| 0.4 | 2.5 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.4 | 3.6 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.3 | 1.6 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.3 | 5.9 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.3 | 1.9 | GO:0005638 | lamin filament(GO:0005638) |
| 0.2 | 0.8 | GO:0031983 | vesicle lumen(GO:0031983) |
| 0.2 | 2.1 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.2 | 3.8 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.2 | 1.1 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.2 | 2.3 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 3.4 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.1 | 7.5 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.1 | 0.7 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.1 | 0.5 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
| 0.1 | 1.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 1.3 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 4.2 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 0.4 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
| 0.1 | 2.8 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.1 | 0.4 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.1 | 0.5 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.1 | 0.3 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 0.1 | 0.7 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 8.3 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 2.2 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 2.1 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 5.0 | GO:0005657 | replication fork(GO:0005657) |
| 0.1 | 1.9 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.1 | 1.2 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.1 | 1.5 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
| 0.1 | 14.3 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 7.1 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.1 | 0.8 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 0.2 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.1 | 3.8 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.3 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.0 | 2.2 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.6 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 0.8 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.2 | GO:0000791 | euchromatin(GO:0000791) |
| 0.0 | 0.8 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.4 | GO:0070578 | RISC-loading complex(GO:0070578) |
| 0.0 | 5.7 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.6 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 0.7 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 3.0 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 1.4 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 0.7 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.0 | 0.4 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 3.4 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.0 | 0.9 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.2 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
| 0.0 | 5.1 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 1.1 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 0.4 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 2.5 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 1.9 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 5.7 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 7.3 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 3.1 | GO:0043235 | receptor complex(GO:0043235) |
| 0.0 | 0.2 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.0 | 2.8 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.0 | 4.3 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 0.6 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.0 | 0.7 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 3.1 | GO:0098793 | presynapse(GO:0098793) |
| 0.0 | 0.7 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 4.8 | GO:0030425 | dendrite(GO:0030425) |
| 0.0 | 0.1 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
| 0.0 | 0.2 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.0 | 0.1 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 1.5 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 0.5 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 0.4 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.2 | GO:0098827 | endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827) |
| 0.0 | 1.1 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 0.6 | GO:0055037 | recycling endosome(GO:0055037) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 22.4 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 3.3 | 9.9 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 2.4 | 7.1 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
| 1.9 | 5.7 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
| 1.4 | 9.8 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 1.4 | 5.5 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
| 1.4 | 6.8 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
| 1.3 | 5.3 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 1.3 | 3.9 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
| 0.8 | 2.3 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 0.8 | 9.3 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.8 | 9.0 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
| 0.7 | 5.9 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.7 | 2.2 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
| 0.7 | 2.8 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.7 | 2.8 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.7 | 3.5 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.6 | 4.9 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
| 0.6 | 5.7 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.6 | 10.5 | GO:0030275 | LRR domain binding(GO:0030275) |
| 0.5 | 2.2 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.5 | 2.1 | GO:0086075 | gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763) |
| 0.5 | 16.2 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.5 | 1.5 | GO:0015228 | coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122) |
| 0.4 | 3.4 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
| 0.4 | 2.5 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.4 | 1.2 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.4 | 1.5 | GO:0004096 | catalase activity(GO:0004096) |
| 0.4 | 2.7 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.4 | 1.5 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.4 | 1.1 | GO:0071723 | lipopeptide binding(GO:0071723) |
| 0.3 | 1.0 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
| 0.3 | 4.2 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.3 | 0.9 | GO:0008504 | monoamine transmembrane transporter activity(GO:0008504) |
| 0.3 | 0.9 | GO:0047710 | bis(5'-adenosyl)-triphosphatase activity(GO:0047710) |
| 0.3 | 8.6 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.3 | 2.1 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 0.2 | 0.7 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.2 | 1.5 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.2 | 0.7 | GO:0036361 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
| 0.2 | 1.2 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.2 | 2.8 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
| 0.2 | 5.0 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.2 | 2.3 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.2 | 0.9 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 0.2 | 1.6 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 0.2 | 1.4 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.2 | 1.5 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.2 | 3.6 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.2 | 1.5 | GO:0016312 | inositol bisphosphate phosphatase activity(GO:0016312) |
| 0.2 | 2.9 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.2 | 0.7 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834) |
| 0.2 | 0.5 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 0.2 | 0.8 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 0.2 | 0.6 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
| 0.2 | 2.5 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.2 | 4.5 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.1 | 1.0 | GO:0016918 | retinal binding(GO:0016918) |
| 0.1 | 0.4 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.1 | 1.9 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 3.0 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 2.4 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 5.4 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.1 | 2.9 | GO:0035250 | UDP-galactosyltransferase activity(GO:0035250) |
| 0.1 | 3.7 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 4.5 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 0.5 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.1 | 0.3 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
| 0.1 | 1.6 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
| 0.1 | 1.6 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.1 | 0.2 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
| 0.1 | 1.9 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 0.7 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.1 | 1.9 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.1 | 0.6 | GO:0090482 | vitamin transmembrane transporter activity(GO:0090482) |
| 0.1 | 5.1 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.1 | 2.1 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.1 | 2.2 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 0.5 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
| 0.1 | 0.5 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.1 | 3.9 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.1 | 2.3 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 0.3 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
| 0.1 | 0.7 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 1.8 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 2.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 4.0 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.1 | 0.6 | GO:0017171 | serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171) |
| 0.1 | 0.6 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
| 0.1 | 1.7 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 0.2 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.1 | 0.6 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 0.2 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.0 | 0.1 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
| 0.0 | 1.5 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 0.2 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 0.0 | 0.8 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.5 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) DNA binding, bending(GO:0008301) |
| 0.0 | 1.3 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.4 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.0 | 4.6 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
| 0.0 | 1.1 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 0.4 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 0.0 | 0.2 | GO:1990188 | euchromatin binding(GO:1990188) |
| 0.0 | 0.6 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.6 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.0 | 0.4 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
| 0.0 | 0.1 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
| 0.0 | 2.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 1.5 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 1.6 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 1.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 1.1 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 1.9 | GO:0015297 | antiporter activity(GO:0015297) |
| 0.0 | 0.4 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.0 | 0.5 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 0.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 0.5 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.0 | 2.0 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 2.1 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 0.6 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.2 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 2.3 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.9 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.0 | 1.7 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 0.1 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 0.0 | 0.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 0.7 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 0.2 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 0.8 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 3.1 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.0 | 0.2 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.0 | 0.7 | GO:0016879 | ligase activity, forming carbon-nitrogen bonds(GO:0016879) |
| 0.0 | 0.1 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.0 | 2.7 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 3.3 | GO:0003779 | actin binding(GO:0003779) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 27.3 | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.4 | 5.8 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
| 0.3 | 8.6 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.2 | 7.0 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 7.4 | PID_FGF_PATHWAY | FGF signaling pathway |
| 0.1 | 5.1 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
| 0.1 | 8.2 | PID_FOXO_PATHWAY | FoxO family signaling |
| 0.1 | 6.3 | PID_SHP2_PATHWAY | SHP2 signaling |
| 0.1 | 2.1 | PID_ATM_PATHWAY | ATM pathway |
| 0.1 | 2.1 | ST_GA12_PATHWAY | G alpha 12 Pathway |
| 0.1 | 3.2 | PID_AP1_PATHWAY | AP-1 transcription factor network |
| 0.1 | 3.7 | PID_INSULIN_PATHWAY | Insulin Pathway |
| 0.1 | 2.1 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 3.1 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 3.9 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.1 | 3.1 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 0.5 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
| 0.1 | 2.3 | PID_REELIN_PATHWAY | Reelin signaling pathway |
| 0.1 | 1.7 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
| 0.1 | 1.1 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 2.2 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
| 0.1 | 2.5 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
| 0.0 | 4.3 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 1.3 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
| 0.0 | 2.4 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
| 0.0 | 0.4 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 4.4 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.9 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 4.8 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 1.8 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 3.2 | NABA_MATRISOME_ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.0 | 1.2 | ST_FAS_SIGNALING_PATHWAY | Fas Signaling Pathway |
| 0.0 | 0.4 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
| 0.0 | 0.4 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 0.3 | PID_ARF_3PATHWAY | Arf1 pathway |
| 0.0 | 0.2 | PID_ERBB2_ERBB3_PATHWAY | ErbB2/ErbB3 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 22.1 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 1.0 | 9.6 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.6 | 13.8 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.5 | 6.1 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.4 | 2.2 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.3 | 23.2 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.3 | 2.8 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.2 | 6.5 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.2 | 6.9 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.2 | 7.8 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.2 | 3.1 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.2 | 3.9 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.2 | 3.7 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
| 0.2 | 5.9 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.2 | 5.0 | REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.2 | 7.6 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 1.7 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
| 0.1 | 3.4 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 4.2 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 4.6 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 2.5 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 1.6 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.1 | 1.1 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.1 | 1.9 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
| 0.1 | 0.5 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.1 | 0.7 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.1 | 2.3 | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 0.1 | 1.0 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.1 | 0.5 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.1 | 0.8 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.1 | 1.5 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 1.5 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.1 | 0.6 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.6 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.0 | 1.2 | REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 1.8 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.6 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 2.6 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 1.1 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.3 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 1.5 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 3.5 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 0.4 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 1.0 | REACTOME_PHASE_II_CONJUGATION | Genes involved in Phase II conjugation |
| 0.0 | 0.5 | REACTOME_TRIGLYCERIDE_BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.0 | 2.3 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.6 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.5 | REACTOME_EXTENSION_OF_TELOMERES | Genes involved in Extension of Telomeres |
| 0.0 | 0.6 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.2 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.4 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 0.1 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.0 | 0.4 | REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
