Motif ID: Tbx19

Z-value: 0.862


Transcription factors associated with Tbx19:

Gene SymbolEntrez IDGene Name
Tbx19 ENSMUSG00000026572.5 Tbx19



Activity profile for motif Tbx19.

activity profile for motif Tbx19


Sorted Z-values histogram for motif Tbx19

Sorted Z-values for motif Tbx19



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx19

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_101468164 12.423 ENSMUST00000001347.6
 Rnd2
Rho family GTPase 2
chr18_-_82406777 9.516 ENSMUST00000065224.6
 Galr1
galanin receptor 1
chr7_-_132776855 7.121 ENSMUST00000106168.1
 Fam53b
family with sequence similarity 53, member B
chr9_+_15520830 6.398 ENSMUST00000178999.1
 Smco4
single-pass membrane protein with coiled-coil domains 4
chr2_-_113758638 6.372 ENSMUST00000099575.3
 Grem1
gremlin 1
chr9_-_21760275 6.073 ENSMUST00000098942.4
 Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr3_+_94693556 5.911 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
 Selenbp2



selenium binding protein 2



chr7_-_132786914 5.577 ENSMUST00000065371.7
ENSMUST00000106166.1
 Fam53b

family with sequence similarity 53, member B

chr17_+_6978860 5.496 ENSMUST00000089119.5
ENSMUST00000179728.1
 Rnaset2b

ribonuclease T2B

chr6_-_54593139 4.731 ENSMUST00000046520.6
 Fkbp14
FK506 binding protein 14
chr11_-_101171302 4.178 ENSMUST00000164474.1
ENSMUST00000043397.7
 Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3

chr17_-_35027909 3.944 ENSMUST00000040151.2
 Sapcd1
suppressor APC domain containing 1
chr7_+_130936172 3.925 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr10_+_20347788 3.369 ENSMUST00000169712.1
 Mtfr2
mitochondrial fission regulator 2
chr2_+_179442427 3.144 ENSMUST00000000314.6
 Cdh4
cadherin 4
chrY_+_897782 3.050 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr16_-_45844303 2.976 ENSMUST00000036355.6
 Phldb2
pleckstrin homology-like domain, family B, member 2
chr6_+_124808885 2.952 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
 Spsb2


splA/ryanodine receptor domain and SOCS box containing 2


chr14_-_66124482 2.667 ENSMUST00000070515.1
 Ephx2
epoxide hydrolase 2, cytoplasmic
chr14_+_115042752 2.648 ENSMUST00000134140.2
 Mir17hg
Mir17 host gene 1 (non-protein coding)
chr13_-_21453714 2.581 ENSMUST00000032820.7
ENSMUST00000110485.1
 Zscan26

zinc finger and SCAN domain containing 26

chr1_-_93342734 2.579 ENSMUST00000027493.3
 Pask
PAS domain containing serine/threonine kinase
chr10_-_86011833 2.347 ENSMUST00000105304.1
ENSMUST00000061699.5
 Bpifc

BPI fold containing family C

chr7_+_39517744 2.323 ENSMUST00000108015.1
 Zfp619
zinc finger protein 619
chr4_+_62525369 2.307 ENSMUST00000062145.1
 4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr5_-_115484297 2.292 ENSMUST00000112067.1
 Sirt4
sirtuin 4
chr8_-_41133697 2.202 ENSMUST00000155055.1
ENSMUST00000059115.6
ENSMUST00000145860.1
 Mtus1


mitochondrial tumor suppressor 1


chr2_+_175010241 2.179 ENSMUST00000109069.1
ENSMUST00000109070.2
 Gm14444

predicted gene 14444

chrM_+_9870 2.126 ENSMUST00000084013.1
 mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr12_-_98259416 2.097 ENSMUST00000021390.7
 Galc
galactosylceramidase
chr5_+_114707760 2.024 ENSMUST00000094441.4
 Tchp
trichoplein, keratin filament binding
chr11_+_80089385 2.024 ENSMUST00000108239.1
ENSMUST00000017694.5
 Atad5

ATPase family, AAA domain containing 5

chr7_-_3720382 1.969 ENSMUST00000078451.6
 Pirb
paired Ig-like receptor B
chr1_+_15712303 1.967 ENSMUST00000170146.1
 Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr2_-_177578199 1.886 ENSMUST00000108945.1
ENSMUST00000108943.1
 Gm14406

predicted gene 14406

chr7_+_70388305 1.810 ENSMUST00000080024.5
 B130024G19Rik
RIKEN cDNA B130024G19 gene
chr2_-_175067763 1.765 ENSMUST00000072895.3
ENSMUST00000109066.1
 Gm14393

predicted gene 14393

chr1_-_24612700 1.743 ENSMUST00000088336.1
 Gm10222
predicted gene 10222
chr6_+_17749170 1.715 ENSMUST00000053148.7
ENSMUST00000115417.3
 St7

suppression of tumorigenicity 7

chr5_+_96173940 1.660 ENSMUST00000048361.8
 Gm2840
predicted gene 2840
chr2_-_177324307 1.581 ENSMUST00000108959.2
 Gm14412
predicted gene 14412
chr9_+_73044833 1.528 ENSMUST00000184146.1
ENSMUST00000034722.4
 Rab27a

RAB27A, member RAS oncogene family

chr4_+_155562348 1.503 ENSMUST00000030939.7
 Nadk
NAD kinase
chr4_+_136347286 1.478 ENSMUST00000140052.2
 9130020K20Rik
RIKEN cDNA 9130020K20 gene
chr6_-_119467210 1.459 ENSMUST00000118120.1
 Wnt5b
wingless-related MMTV integration site 5B
chr9_-_103230262 1.394 ENSMUST00000165296.1
ENSMUST00000112645.1
ENSMUST00000166836.1
 Trf

Gm20425
transferrin

predicted gene 20425
chr11_-_60046477 1.379 ENSMUST00000000310.7
ENSMUST00000102693.2
ENSMUST00000148512.1
 Pemt


phosphatidylethanolamine N-methyltransferase


chrM_+_10167 1.374 ENSMUST00000082414.1
 mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr7_-_140955960 1.344 ENSMUST00000081649.8
 Ifitm2
interferon induced transmembrane protein 2
chr9_-_124440899 1.326 ENSMUST00000180233.1
 Gm20783
predicted gene, 20783
chr19_-_3414464 1.322 ENSMUST00000025842.6
 Gal
galanin
chr3_-_97610156 1.312 ENSMUST00000029730.4
 Chd1l
chromodomain helicase DNA binding protein 1-like
chr1_+_59256906 1.291 ENSMUST00000160662.1
ENSMUST00000114248.2
 Cdk15

cyclin-dependent kinase 15

chr1_+_156838915 1.192 ENSMUST00000111720.1
 Angptl1
angiopoietin-like 1
chr9_-_46319984 1.159 ENSMUST00000159565.1
 4931429L15Rik
RIKEN cDNA 4931429L15 gene
chr1_+_58646608 1.157 ENSMUST00000081455.4
 Gm10068
predicted gene 10068
chr5_+_138187485 1.156 ENSMUST00000110934.2
 Cnpy4
canopy 4 homolog (zebrafish)
chr19_+_5474681 1.127 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
 Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr4_+_122836236 1.125 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
 Ppt1


palmitoyl-protein thioesterase 1


chr2_+_177080256 1.120 ENSMUST00000134614.1
ENSMUST00000108968.1
 Gm14401

predicted gene 14401

chr11_-_116027961 1.055 ENSMUST00000106454.1
 H3f3b
H3 histone, family 3B
chr8_-_4275886 1.005 ENSMUST00000003029.7
 Timm44
translocase of inner mitochondrial membrane 44
chr5_-_92278155 0.905 ENSMUST00000159345.1
ENSMUST00000113102.3
 Naaa

N-acylethanolamine acid amidase

chr4_+_3940747 0.878 ENSMUST00000119403.1
 Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr9_-_54193442 0.868 ENSMUST00000034811.7
 Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
chr7_+_28741968 0.851 ENSMUST00000094632.4
 Sars2
seryl-aminoacyl-tRNA synthetase 2
chr6_+_90465287 0.725 ENSMUST00000113530.1
 Klf15
Kruppel-like factor 15
chr7_-_80947765 0.718 ENSMUST00000026818.5
ENSMUST00000117383.1
ENSMUST00000119980.1
 Sec11a


SEC11 homolog A (S. cerevisiae)


chr11_+_101442298 0.684 ENSMUST00000077856.6
 Rpl27
ribosomal protein L27
chr5_-_121191365 0.657 ENSMUST00000100770.2
ENSMUST00000054547.7
 Ptpn11

protein tyrosine phosphatase, non-receptor type 11

chr2_-_132253227 0.633 ENSMUST00000028817.6
 Pcna
proliferating cell nuclear antigen
chr1_+_127868773 0.613 ENSMUST00000037649.5
 Rab3gap1
RAB3 GTPase activating protein subunit 1
chr17_+_26113286 0.588 ENSMUST00000025010.7
 Tmem8
transmembrane protein 8 (five membrane-spanning domains)
chr9_-_25151772 0.576 ENSMUST00000008573.7
 Herpud2
HERPUD family member 2
chr17_-_13131791 0.529 ENSMUST00000084966.5
 Unc93a
unc-93 homolog A (C. elegans)
chr11_+_101442440 0.505 ENSMUST00000107249.1
 Rpl27
ribosomal protein L27
chr17_-_32350569 0.503 ENSMUST00000050214.7
 Akap8l
A kinase (PRKA) anchor protein 8-like
chr6_+_86195214 0.501 ENSMUST00000032066.9
 Tgfa
transforming growth factor alpha
chr6_+_42286709 0.481 ENSMUST00000163936.1
 Clcn1
chloride channel 1
chr6_+_129180613 0.448 ENSMUST00000032260.5
 Clec2d
C-type lectin domain family 2, member d
chr13_-_23562369 0.427 ENSMUST00000105107.1
 Hist1h3e
histone cluster 1, H3e
chr6_-_85451248 0.389 ENSMUST00000113770.1
ENSMUST00000032080.2
 Pradc1

protease-associated domain containing 1

chr9_-_117252450 0.387 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
 Rbms3


RNA binding motif, single stranded interacting protein


chr4_-_12087912 0.378 ENSMUST00000050686.3
 Tmem67
transmembrane protein 67
chr1_+_183388981 0.343 ENSMUST00000097043.5
 Taf1a
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A
chr3_-_153944632 0.341 ENSMUST00000072697.6
 Acadm
acyl-Coenzyme A dehydrogenase, medium chain
chr6_-_122340525 0.295 ENSMUST00000112600.2
 Phc1
polyhomeotic-like 1 (Drosophila)
chrX_+_140664908 0.269 ENSMUST00000112990.1
ENSMUST00000112988.1
 Mid2

midline 2

chr5_-_38491948 0.222 ENSMUST00000129099.1
 Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr16_-_30587537 0.205 ENSMUST00000117363.2
 Lsg1
large subunit GTPase 1 homolog (S. cerevisiae)
chr1_-_57406443 0.197 ENSMUST00000160837.1
ENSMUST00000161780.1
 Tyw5

tRNA-yW synthesizing protein 5

chr2_-_148046896 0.172 ENSMUST00000172928.1
ENSMUST00000047315.3
 Foxa2

forkhead box A2

chr17_+_25773769 0.171 ENSMUST00000134108.1
ENSMUST00000002350.4
 Narfl

nuclear prelamin A recognition factor-like

chr15_-_78305603 0.147 ENSMUST00000096356.3
 Csf2rb2
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr1_+_185332143 0.146 ENSMUST00000027916.6
ENSMUST00000151769.1
ENSMUST00000110965.1
 Bpnt1


bisphosphate 3'-nucleotidase 1


chr1_+_87404916 0.130 ENSMUST00000173152.1
ENSMUST00000173663.1
 Gigyf2

GRB10 interacting GYF protein 2

chr7_+_12927410 0.128 ENSMUST00000045870.4
 2310014L17Rik
RIKEN cDNA 2310014L17 gene
chr5_-_45856496 0.118 ENSMUST00000087164.3
ENSMUST00000121573.1
 Lcorl

ligand dependent nuclear receptor corepressor-like

chr10_-_78244602 0.088 ENSMUST00000000384.6
 Trappc10
trafficking protein particle complex 10
chr9_-_57606234 0.087 ENSMUST00000045068.8
 Cplx3
complexin 3
chr7_+_44818437 0.077 ENSMUST00000136861.1
 Nup62
nucleoporin 62
chr12_-_58269162 0.062 ENSMUST00000062254.2
 Clec14a
C-type lectin domain family 14, member a
chr17_+_46646225 0.052 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
 Mrpl2


mitochondrial ribosomal protein L2


chr1_-_72212249 0.003 ENSMUST00000048860.7
 Mreg
melanoregulin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
2.1 6.4 GO:1901228 regulation of osteoclast proliferation(GO:0090289) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) negative regulation of bone development(GO:1903011)
0.9 2.7 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.8 12.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.7 0.7 GO:0051462 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
0.7 3.9 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.6 3.0 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.5 1.5 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.5 2.3 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.4 3.0 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 2.0 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.3 2.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.3 2.6 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.3 0.9 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.3 1.1 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.3 12.7 GO:0035411 catenin import into nucleus(GO:0035411)
0.3 2.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.3 1.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 0.9 GO:0035937 androgen catabolic process(GO:0006710) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) testosterone biosynthetic process(GO:0061370) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.2 1.4 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.2 1.1 GO:0098734 protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549) macromolecule depalmitoylation(GO:0098734)
0.2 0.6 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.2 2.0 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 2.0 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.3 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.1 1.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 2.2 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.4 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.2 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 1.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 3.4 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.2 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.1 0.5 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 3.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 2.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.7 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.7 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 1.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.3 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.3 GO:0006468 protein phosphorylation(GO:0006468)
0.0 0.4 GO:0045727 positive regulation of translation(GO:0045727)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.1 GO:0031262 Ndc80 complex(GO:0031262)
0.3 2.0 GO:0045179 apical cortex(GO:0045179)
0.3 1.5 GO:0033093 multivesicular body membrane(GO:0032585) Weibel-Palade body(GO:0033093)
0.2 0.6 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 3.0 GO:0045180 basal cortex(GO:0045180)
0.2 1.4 GO:0005785 signal recognition particle receptor complex(GO:0005785) dense body(GO:0097433)
0.1 5.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.7 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 2.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 2.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.4 GO:0070469 respiratory chain(GO:0070469)
0.0 5.9 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0097361 CIA complex(GO:0097361)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 8.1 GO:0005769 early endosome(GO:0005769)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 1.4 GO:0031526 brush border membrane(GO:0031526)
0.0 20.2 GO:0005615 extracellular space(GO:0005615)
0.0 3.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.8 GO:0004966 galanin receptor activity(GO:0004966)
0.7 6.4 GO:0036122 BMP binding(GO:0036122)
0.5 5.9 GO:0008430 selenium binding(GO:0008430)
0.5 2.7 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.4 3.0 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.3 0.9 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.2 0.6 GO:0032139 DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139)
0.2 1.4 GO:0015091 signal recognition particle binding(GO:0005047) ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 3.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 0.9 GO:0070330 aromatase activity(GO:0070330)
0.2 1.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.3 GO:0070403 NAD+ binding(GO:0070403)
0.1 2.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 3.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 2.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.3 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.1 1.5 GO:0031489 myosin V binding(GO:0031489)
0.1 5.5 GO:0004540 ribonuclease activity(GO:0004540)
0.1 0.2 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.1 0.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 10.4 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 1.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 1.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin binding(GO:0030332)
0.0 0.5 GO:0034237 lamin binding(GO:0005521) protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.6 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.4 PID_BMP_PATHWAY BMP receptor signaling
0.1 6.1 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.7 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.5 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 2.3 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID_BARD1_PATHWAY BARD1 signaling events
0.0 1.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 10.8 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 3.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 4.7 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.5 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.6 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.1 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.4 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 6.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.7 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.9 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.5 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 3.0 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation