---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_26229707	36.858	ENSMUST00000060716.5 ENSMUST00000164660.1	Samd3	sterile alpha motif domain containing 3
chr1_+_6730051	31.585	ENSMUST00000043578.6 ENSMUST00000131467.1 ENSMUST00000150761.1 ENSMUST00000151281.1	St18	suppression of tumorigenicity 18
chr2_-_13011747	24.716	ENSMUST00000061545.5	C1ql3	C1q-like 3
chr1_-_138847579	22.006	ENSMUST00000093486.3 ENSMUST00000046870.6	Lhx9	LIM homeobox protein 9
chr1_+_6730135	20.617	ENSMUST00000155921.1	St18	suppression of tumorigenicity 18
chr6_+_15196949	19.855	ENSMUST00000151301.1 ENSMUST00000131414.1 ENSMUST00000140557.1 ENSMUST00000115469.1	Foxp2	forkhead box P2
chr4_+_125490688	19.426	ENSMUST00000030676.7	Grik3	glutamate receptor, ionotropic, kainate 3
chr7_-_28302238	14.510	ENSMUST00000108315.3	Dll3	delta-like 3 (Drosophila)
chr1_+_132316112	12.351	ENSMUST00000082125.5 ENSMUST00000072177.7	Nuak2	NUAK family, SNF1-like kinase, 2
chr1_+_153665274	12.237	ENSMUST00000152114.1 ENSMUST00000111812.1	Rgs8	regulator of G-protein signaling 8
chr2_-_57114970	10.378	ENSMUST00000028166.2	Nr4a2	nuclear receptor subfamily 4, group A, member 2
chr17_+_29093763	10.287	ENSMUST00000023829.6	Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)
chr1_+_153665666	10.035	ENSMUST00000111814.1 ENSMUST00000111810.1	Rgs8	regulator of G-protein signaling 8
chr1_+_153665587	9.056	ENSMUST00000147700.1	Rgs8	regulator of G-protein signaling 8
chr1_+_153665627	8.512	ENSMUST00000147482.1	Rgs8	regulator of G-protein signaling 8
chr18_-_46212595	7.113	ENSMUST00000037011.4	Trim36	tripartite motif-containing 36
chr11_-_84068357	7.020	ENSMUST00000100705.4	Dusp14	dual specificity phosphatase 14
chr13_-_89742490	6.935	ENSMUST00000109546.2	Vcan	versican
chr11_-_84068766	6.712	ENSMUST00000018792.5	Dusp14	dual specificity phosphatase 14
chr2_+_164562579	6.582	ENSMUST00000017867.3 ENSMUST00000109344.2 ENSMUST00000109345.2	Wfdc2	WAP four-disulfide core domain 2
chr4_-_35845204	6.055	ENSMUST00000164772.1 ENSMUST00000065173.2	Lingo2	leucine rich repeat and Ig domain containing 2
chr9_-_43239816	6.048	ENSMUST00000034512.5	Oaf	OAF homolog (Drosophila)
chr7_-_141443989	5.989	ENSMUST00000026580.5	Lrdd	leucine-rich and death domain containing
chr6_-_94700137	5.593	ENSMUST00000101126.2 ENSMUST00000032105.4	Lrig1	leucine-rich repeats and immunoglobulin-like domains 1
chr6_+_7555053	4.502	ENSMUST00000090679.2 ENSMUST00000184986.1	Tac1	tachykinin 1
chr12_+_3891728	4.502	ENSMUST00000172689.1 ENSMUST00000111186.1	Dnmt3a	DNA methyltransferase 3A
chr10_-_92162753	4.221	ENSMUST00000182197.1	Rmst	rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr4_-_132510493	3.833	ENSMUST00000030724.8	Sesn2	sestrin 2
chr3_+_75557530	3.778	ENSMUST00000161776.1 ENSMUST00000029423.8	Serpini1	serine (or cysteine) peptidase inhibitor, clade I, member 1
chr7_-_115824699	3.757	ENSMUST00000169129.1	Sox6	SRY-box containing gene 6
chr17_+_47630690	3.525	ENSMUST00000024779.8	Usp49	ubiquitin specific peptidase 49
chr17_-_70849644	3.489	ENSMUST00000134654.1 ENSMUST00000172229.1 ENSMUST00000127719.1	Tgif1	TGFB-induced factor homeobox 1
chr16_-_50330987	3.444	ENSMUST00000114488.1	Bbx	bobby sox homolog (Drosophila)
chr18_+_60963517	3.315	ENSMUST00000115295.2 ENSMUST00000039904.6	Camk2a	calcium/calmodulin-dependent protein kinase II alpha
chr4_-_134018829	3.199	ENSMUST00000051674.2	Lin28a	lin-28 homolog A (C. elegans)
chr5_+_115908644	3.092	ENSMUST00000141101.1	Cit	citron
chr19_+_20601958	3.090	ENSMUST00000087638.3	Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1
chr10_-_120899067	3.069	ENSMUST00000092143.5	Msrb3	methionine sulfoxide reductase B3
chrX_-_162829379	3.044	ENSMUST00000041370.4 ENSMUST00000112316.2 ENSMUST00000112315.1	Txlng	taxilin gamma
chr11_+_98348404	2.948	ENSMUST00000078694.6	Ppp1r1b	protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr4_-_123750236	2.918	ENSMUST00000102636.3	Akirin1	akirin 1
chr2_+_20519776	2.880	ENSMUST00000114604.2 ENSMUST00000066509.3	Etl4	enhancer trap locus 4
chr8_-_8639363	2.801	ENSMUST00000152698.1	Efnb2	ephrin B2
chr2_+_54436317	2.800	ENSMUST00000112636.1 ENSMUST00000112635.1 ENSMUST00000112634.1	Galnt13	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
chr6_+_61180313	2.637	ENSMUST00000126214.1	Ccser1	coiled-coil serine rich 1
chrX_+_142681398	2.495	ENSMUST00000112889.1 ENSMUST00000101198.2 ENSMUST00000112891.1 ENSMUST00000087333.2	Tmem164	transmembrane protein 164
chr1_-_69108039	2.451	ENSMUST00000121473.1	Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr8_+_106870827	2.450	ENSMUST00000176144.1 ENSMUST00000175987.1	Has3	hyaluronan synthase 3
chr16_-_16527364	2.424	ENSMUST00000069284.7	Fgd4	FYVE, RhoGEF and PH domain containing 4
chr1_-_105356658	2.371	ENSMUST00000058688.5 ENSMUST00000172299.1	Rnf152	ring finger protein 152
chr14_-_51988829	2.340	ENSMUST00000181008.1	Gm16617	predicted gene, 16617
chrX_-_53269020	2.331	ENSMUST00000114838.1	Fam122b	family with sequence similarity 122, member B
chr1_+_131970589	2.301	ENSMUST00000027695.6	Slc45a3	solute carrier family 45, member 3
chr9_+_35421541	2.251	ENSMUST00000119129.2	Cdon	cell adhesion molecule-related/down-regulated by oncogenes
chr10_-_85916902	2.139	ENSMUST00000037646.7	Prdm4	PR domain containing 4
chr9_+_27299205	2.136	ENSMUST00000115247.1 ENSMUST00000133213.1	Igsf9b	immunoglobulin superfamily, member 9B
chr9_-_95845215	1.893	ENSMUST00000093800.2	Pls1	plastin 1 (I-isoform)
chr11_-_94507337	1.865	ENSMUST00000040692.8	Mycbpap	MYCBP associated protein
chr9_+_108296853	1.850	ENSMUST00000035230.5	Amt	aminomethyltransferase
chrX_-_152016269	1.850	ENSMUST00000026288.4	Ribc1	RIB43A domain with coiled-coils 1
chr9_-_69760924	1.845	ENSMUST00000071281.4	Foxb1	forkhead box B1
chr5_-_24329556	1.840	ENSMUST00000115098.2	Kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr2_+_27079371	1.832	ENSMUST00000091233.6	Adamtsl2	ADAMTS-like 2
chr14_+_56887795	1.831	ENSMUST00000022511.8	Zmym2	zinc finger, MYM-type 2
chr3_+_51415986	1.827	ENSMUST00000029303.7	Naa15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chrM_+_9870	1.751	ENSMUST00000084013.1	mt-Nd4l	mitochondrially encoded NADH dehydrogenase 4L
chr6_+_50110837	1.726	ENSMUST00000167628.1	Mpp6	membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr3_+_102734496	1.705	ENSMUST00000029451.5	Tspan2	tetraspanin 2
chr4_+_43641262	1.660	ENSMUST00000123351.1 ENSMUST00000128549.1	Npr2	natriuretic peptide receptor 2
chr6_-_21851914	1.541	ENSMUST00000134635.1 ENSMUST00000123116.1 ENSMUST00000120965.1	Tspan12	tetraspanin 12
chr13_-_43304153	1.507	ENSMUST00000055341.5	Gfod1	glucose-fructose oxidoreductase domain containing 1
chr1_-_24612700	1.457	ENSMUST00000088336.1	Gm10222	predicted gene 10222
chr4_+_84884276	1.446	ENSMUST00000047023.6	Cntln	centlein, centrosomal protein
chr6_+_42286709	1.445	ENSMUST00000163936.1	Clcn1	chloride channel 1
chr2_+_68861433	1.439	ENSMUST00000028426.2	Cers6	ceramide synthase 6
chr4_+_84884418	1.399	ENSMUST00000169371.2	Cntln	centlein, centrosomal protein
chrX_+_42151002	1.389	ENSMUST00000123245.1	Stag2	stromal antigen 2
chr2_+_68861564	1.365	ENSMUST00000176018.1	Cers6	ceramide synthase 6
chrX_+_41401304	1.301	ENSMUST00000076349.5	Gria3	glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr1_-_161876656	1.280	ENSMUST00000048377.5	Suco	SUN domain containing ossification factor
chrM_+_10167	1.262	ENSMUST00000082414.1	mt-Nd4	mitochondrially encoded NADH dehydrogenase 4
chrM_+_7759	1.255	ENSMUST00000082407.1 ENSMUST00000082408.1	mt-Atp8 mt-Atp6	mitochondrially encoded ATP synthase 8 mitochondrially encoded ATP synthase 6
chr6_-_127769427	1.128	ENSMUST00000032500.8	Prmt8	protein arginine N-methyltransferase 8
chrX_+_42150672	1.119	ENSMUST00000069619.7	Stag2	stromal antigen 2
chr7_-_132813715	1.044	ENSMUST00000134946.1	Fam53b	family with sequence similarity 53, member B
chrX_+_20425688	0.999	ENSMUST00000115384.2	Phf16	PHD finger protein 16
chr14_+_62292475	0.988	ENSMUST00000166879.1	Rnaseh2b	ribonuclease H2, subunit B
chr18_-_42899470	0.969	ENSMUST00000120632.1	Ppp2r2b	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr7_-_132813799	0.942	ENSMUST00000097998.2	Fam53b	family with sequence similarity 53, member B
chr13_+_93304066	0.925	ENSMUST00000109493.1	Homer1	homer homolog 1 (Drosophila)
chr4_+_11191354	0.896	ENSMUST00000170901.1	Ccne2	cyclin E2
chr11_-_22286795	0.890	ENSMUST00000109563.2 ENSMUST00000180360.1	Ehbp1	EH domain binding protein 1
chrX_+_56454871	0.881	ENSMUST00000039374.2 ENSMUST00000101553.2	Ddx26b	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr7_-_132813528	0.865	ENSMUST00000097999.2	Fam53b	family with sequence similarity 53, member B
chrX_+_163909132	0.848	ENSMUST00000033734.7 ENSMUST00000112294.2	Ap1s2	adaptor-related protein complex 1, sigma 2 subunit
chr2_-_60125651	0.840	ENSMUST00000112550.1	Baz2b	bromodomain adjacent to zinc finger domain, 2B
chr19_-_19001099	0.836	ENSMUST00000040153.8 ENSMUST00000112828.1	Rorb	RAR-related orphan receptor beta
chr17_+_48932368	0.823	ENSMUST00000046254.2	Lrfn2	leucine rich repeat and fibronectin type III domain containing 2
chr10_+_56377300	0.818	ENSMUST00000068581.7	Gja1	gap junction protein, alpha 1
chr9_-_13818665	0.803	ENSMUST00000150893.1 ENSMUST00000124883.1	Cep57	centrosomal protein 57
chr16_-_56024628	0.795	ENSMUST00000119981.1 ENSMUST00000096021.3	Pcnp	PEST proteolytic signal containing nuclear protein
chr18_-_42899294	0.786	ENSMUST00000117687.1	Ppp2r2b	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chrX_+_41401476	0.778	ENSMUST00000165288.1	Gria3	glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr12_+_55598917	0.715	ENSMUST00000051857.3	Insm2	insulinoma-associated 2
chr5_-_24601961	0.675	ENSMUST00000030791.7	Smarcd3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr15_+_99670574	0.648	ENSMUST00000023758.7	Asic1	acid-sensing (proton-gated) ion channel 1
chr4_+_41760454	0.599	ENSMUST00000108040.1	Il11ra1	interleukin 11 receptor, alpha chain 1
chr5_+_120513102	0.584	ENSMUST00000111889.1	Slc8b1	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr8_-_31918203	0.583	ENSMUST00000073884.4	Nrg1	neuregulin 1
chr4_-_34882919	0.571	ENSMUST00000098163.2 ENSMUST00000047950.5	Zfp292	zinc finger protein 292
chr12_+_78861693	0.558	ENSMUST00000071230.7	Eif2s1	eukaryotic translation initiation factor 2, subunit 1 alpha
chrX_+_153006461	0.558	ENSMUST00000095755.3	Usp51	ubiquitin specific protease 51
chr4_-_82505749	0.532	ENSMUST00000107245.2 ENSMUST00000107246.1	Nfib	nuclear factor I/B
chr1_+_170214826	0.514	ENSMUST00000159201.1 ENSMUST00000055830.1	4930500M09Rik	RIKEN cDNA 4930500M09 gene
chr6_+_42286676	0.499	ENSMUST00000031894.6	Clcn1	chloride channel 1
chr17_+_35135695	0.476	ENSMUST00000174478.1 ENSMUST00000174281.2 ENSMUST00000173550.1	Bag6	BCL2-associated athanogene 6
chr1_-_126830786	0.466	ENSMUST00000162646.1	Nckap5	NCK-associated protein 5
chr17_-_56982120	0.448	ENSMUST00000056113.4	Acer1	alkaline ceramidase 1
chr1_-_126830632	0.404	ENSMUST00000112583.1 ENSMUST00000094609.3	Nckap5	NCK-associated protein 5
chr15_-_98831498	0.399	ENSMUST00000168846.1	Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr10_-_128211788	0.381	ENSMUST00000061995.8	Spryd4	SPRY domain containing 4
chr19_+_21272276	0.378	ENSMUST00000025659.4	Zfand5	zinc finger, AN1-type domain 5
chr10_-_86705485	0.372	ENSMUST00000020238.7	Hsp90b1	heat shock protein 90, beta (Grp94), member 1
chr15_+_80623499	0.351	ENSMUST00000043149.7	Grap2	GRB2-related adaptor protein 2
chr1_+_74236479	0.344	ENSMUST00000113820.2 ENSMUST00000006467.7 ENSMUST00000113819.1	Arpc2	actin related protein 2/3 complex, subunit 2
chr14_+_31251454	0.343	ENSMUST00000022458.4	Bap1	Brca1 associated protein 1
chr12_-_56345862	0.335	ENSMUST00000021416.7	Mbip	MAP3K12 binding inhibitory protein 1
chr10_+_4710119	0.300	ENSMUST00000105588.1 ENSMUST00000105589.1	Esr1	estrogen receptor 1 (alpha)
chr3_-_103791075	0.277	ENSMUST00000106845.2 ENSMUST00000029438.8 ENSMUST00000121324.1	Hipk1	homeodomain interacting protein kinase 1
chr7_+_46796088	0.274	ENSMUST00000006774.4 ENSMUST00000165031.1	Gtf2h1	general transcription factor II H, polypeptide 1
chr7_+_127746775	0.224	ENSMUST00000033081.7	Fbxl19	F-box and leucine-rich repeat protein 19
chr10_+_86705811	0.224	ENSMUST00000061458.7 ENSMUST00000075632.6	BC030307	cDNA sequence BC030307
chr3_-_154328634	0.219	ENSMUST00000167744.1	Lhx8	LIM homeobox protein 8
chr13_-_96542479	0.207	ENSMUST00000022172.4	Polk	polymerase (DNA directed), kappa
chr11_+_95414078	0.200	ENSMUST00000107724.2 ENSMUST00000150884.1 ENSMUST00000107722.1 ENSMUST00000127713.1	Spop	speckle-type POZ protein
chr7_-_98656530	0.185	ENSMUST00000038359.4	2210018M11Rik	RIKEN cDNA 2210018M11 gene
chr2_+_138278481	0.183	ENSMUST00000075410.4	Btbd3	BTB (POZ) domain containing 3
chr3_-_19311269	0.175	ENSMUST00000099195.3	Pde7a	phosphodiesterase 7A
chr7_-_46795881	0.161	ENSMUST00000107653.1 ENSMUST00000107654.1 ENSMUST00000014562.7 ENSMUST00000152759.1	Hps5	Hermansky-Pudlak syndrome 5 homolog (human)
chrM_+_9452	0.123	ENSMUST00000082411.1	mt-Nd3	mitochondrially encoded NADH dehydrogenase 3
chr7_-_46795661	0.106	ENSMUST00000123725.1	Hps5	Hermansky-Pudlak syndrome 5 homolog (human)
chr15_+_74516196	0.092	ENSMUST00000042035.9	Bai1	brain-specific angiogenesis inhibitor 1
chr18_-_36766198	0.089	ENSMUST00000061522.7	Dnd1	dead end homolog 1 (zebrafish)
chr11_-_69681822	0.061	ENSMUST00000005336.2	Senp3	SUMO/sentrin specific peptidase 3
chr3_+_96629919	0.055	ENSMUST00000048915.6	Rbm8a	RNA binding motif protein 8a
chrX_+_163908982	0.049	ENSMUST00000069041.8	Ap1s2	adaptor-related protein complex 1, sigma 2 subunit
chr1_+_180726019	0.044	ENSMUST00000027780.4	Acbd3	acyl-Coenzyme A binding domain containing 3
chr3_-_103791537	0.035	ENSMUST00000118317.1	Hipk1	homeodomain interacting protein kinase 1
chr1_-_174921813	0.025	ENSMUST00000055294.3	Grem2	gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.4	22.0	GO:0035262	gonad morphogenesis(GO:0035262)
4.4	52.2	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
2.9	14.5	GO:0007386	compartment pattern specification(GO:0007386)
2.8	39.8	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
2.6	10.4	GO:0051866	general adaptation syndrome(GO:0051866)
2.3	4.5	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
1.9	5.6	GO:0032474	otolith morphogenesis(GO:0032474)
1.8	19.4	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
1.7	19.9	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
1.3	3.8	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
1.2	2.5	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.1	10.3	GO:0071493	cellular response to UV-B(GO:0071493)
1.0	2.9	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.8	3.1	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.8	3.1	GO:0030091	protein repair(GO:0030091)
0.8	2.3	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.7	3.5	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.7	0.7	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.6	1.9	GO:0001951	intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.6	1.8	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.6	2.5	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.6	4.5	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.5	2.8	GO:1903847	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.5	1.8	GO:0007412	axon target recognition(GO:0007412)
0.4	1.7	GO:0014005	microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.4	12.5	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.4	3.2	GO:0010587	miRNA catabolic process(GO:0010587)
0.3	3.8	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.3	2.4	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.3	12.4	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.3	1.8	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.3	1.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.3	2.3	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.3	7.1	GO:0007340	acrosome reaction(GO:0007340)
0.3	0.8	GO:0003104	positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.3	2.4	GO:0030035	microspike assembly(GO:0030035)
0.3	1.8	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.3	3.3	GO:0099628	receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.2	3.5	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2	2.2	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.2	0.6	GO:0050915	sensory perception of sour taste(GO:0050915)
0.2	1.9	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2	2.1	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2	1.7	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.2	1.8	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.2	3.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.2	28.7	GO:0050807	regulation of synapse organization(GO:0050807)
0.1	1.8	GO:0060481	lobar bronchus epithelium development(GO:0060481)
0.1	0.5	GO:2000794	regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.1	0.8	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	1.9	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.1	0.8	GO:0046549	retinal cone cell development(GO:0046549)
0.1	5.4	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1	0.3	GO:2000812	response to rapamycin(GO:1901355) regulation of barbed-end actin filament capping(GO:2000812)
0.1	0.3	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1	1.5	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.1	0.3	GO:0060737	prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.1	0.6	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
0.1	1.3	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	0.3	GO:0051189	molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1	1.9	GO:0010842	retina layer formation(GO:0010842)
0.1	0.5	GO:0036506	maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1	2.8	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.1	1.3	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.1	9.0	GO:0010466	negative regulation of peptidase activity(GO:0010466)
0.0	3.0	GO:0030500	regulation of bone mineralization(GO:0030500)
0.0	2.1	GO:0035411	catenin import into nucleus(GO:0035411)
0.0	1.0	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.0	1.8	GO:0042773	ATP synthesis coupled electron transport(GO:0042773)
0.0	0.4	GO:0046512	sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0	0.8	GO:0034453	microtubule anchoring(GO:0034453)
0.0	1.7	GO:0001919	regulation of receptor recycling(GO:0001919)
0.0	0.2	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.6	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.9	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.6	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	2.1	GO:2000177	regulation of neural precursor cell proliferation(GO:2000177)
0.0	0.4	GO:0048745	smooth muscle tissue development(GO:0048745)
0.0	2.9	GO:0060348	bone development(GO:0060348)
0.0	0.8	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.3	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0	0.1	GO:0071384	cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.4	10.3	GO:0070557	PCNA-p21 complex(GO:0070557)
1.1	3.3	GO:0099573	glutamatergic postsynaptic density(GO:0099573)
1.0	39.8	GO:0032809	neuronal cell body membrane(GO:0032809)
0.9	3.8	GO:0031983	vesicle lumen(GO:0031983)
0.6	19.4	GO:0032839	dendrite cytoplasm(GO:0032839)
0.5	1.8	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.4	3.8	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.4	1.9	GO:1990357	terminal web(GO:1990357)
0.3	24.5	GO:0005581	collagen trimer(GO:0005581)
0.3	0.9	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.3	48.3	GO:0032993	protein-DNA complex(GO:0032993)
0.2	1.8	GO:0031415	NatA complex(GO:0031415)
0.2	4.5	GO:0001741	XY body(GO:0001741)
0.2	1.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.1	0.6	GO:0097450	astrocyte end-foot(GO:0097450)
0.1	1.7	GO:0043083	synaptic cleft(GO:0043083)
0.1	0.8	GO:0005916	fascia adherens(GO:0005916)
0.1	1.7	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	1.8	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	7.1	GO:0001669	acrosomal vesicle(GO:0001669)
0.1	0.5	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	0.3	GO:0031084	BLOC-2 complex(GO:0031084)
0.1	0.5	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	3.1	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	2.1	GO:0060077	inhibitory synapse(GO:0060077)
0.1	1.9	GO:0034707	chloride channel complex(GO:0034707)
0.0	4.4	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.3	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.6	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.6	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.7	GO:0071564	npBAF complex(GO:0071564)
0.0	0.2	GO:0001674	female germ cell nucleus(GO:0001674)
0.0	0.3	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	10.9	GO:0016607	nuclear speck(GO:0016607)
0.0	0.4	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	2.3	GO:0070469	respiratory chain(GO:0070469)
0.0	1.9	GO:0035097	histone methyltransferase complex(GO:0035097)
0.0	0.3	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	2.4	GO:0005814	centriole(GO:0005814)
0.0	5.4	GO:0031965	nuclear membrane(GO:0031965)
0.0	1.8	GO:0016605	PML body(GO:0016605)
0.0	0.6	GO:0030673	axolemma(GO:0030673)
0.0	0.9	GO:0043034	costamere(GO:0043034)
0.0	2.3	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	2.4	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.9	19.4	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
3.4	10.3	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.3	6.6	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
1.0	2.9	GO:0031752	D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.9	39.8	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.8	12.5	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.8	2.5	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.8	2.3	GO:0008515	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.6	3.8	GO:0070728	leucine binding(GO:0070728)
0.6	3.1	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.6	4.5	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.5	3.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.5	2.5	GO:0038132	neuregulin binding(GO:0038132)
0.5	1.8	GO:0050436	microfibril binding(GO:0050436)
0.4	14.5	GO:0005112	Notch binding(GO:0005112)
0.4	6.9	GO:0005540	hyaluronic acid binding(GO:0005540)
0.4	1.8	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.3	1.7	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.3	2.8	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.3	4.5	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.3	3.2	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.3	0.8	GO:0008502	melatonin receptor activity(GO:0008502)
0.3	3.3	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2	1.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2	0.8	GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.2	3.1	GO:0070410	co-SMAD binding(GO:0070410)
0.2	2.8	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2	41.9	GO:0001047	core promoter binding(GO:0001047)
0.2	2.1	GO:1990226	histone methyltransferase binding(GO:1990226)
0.1	0.6	GO:0004921	interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1	0.4	GO:0071633	dihydroceramidase activity(GO:0071633)
0.1	0.6	GO:0086038	calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1	1.0	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	1.8	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	1.9	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	3.1	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1	1.8	GO:0008483	transaminase activity(GO:0008483)
0.1	1.7	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	0.9	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1	1.7	GO:0004385	guanylate kinase activity(GO:0004385)
0.1	1.5	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	2.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	2.8	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	11.8	GO:0000287	magnesium ion binding(GO:0000287)
0.0	0.3	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.4	GO:0046790	virion binding(GO:0046790)
0.0	0.6	GO:0045499	chemorepellent activity(GO:0045499)
0.0	1.8	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.4	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.5	GO:0015643	toxic substance binding(GO:0015643)
0.0	6.3	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	1.8	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.8	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	2.5	GO:0030165	PDZ domain binding(GO:0030165)
0.0	4.7	GO:0051015	actin filament binding(GO:0051015)
0.0	0.7	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.6	GO:0022839	ion gated channel activity(GO:0022839)
0.0	0.5	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.3	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.5	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	7.8	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	2.4	GO:0030674	protein binding, bridging(GO:0030674)
0.0	0.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	10.3	SA_G2_AND_M_PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2	6.9	PID_TOLL_ENDOGENOUS_PATHWAY	Endogenous TLR signaling
0.2	3.0	PID_ERBB_NETWORK_PATHWAY	ErbB receptor signaling network
0.2	24.5	NABA_ECM_AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2	14.4	PID_NOTCH_PATHWAY	Notch signaling pathway
0.1	3.3	ST_WNT_CA2_CYCLIC_GMP_PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	5.6	PID_ERBB4_PATHWAY	ErbB4 signaling events
0.1	2.8	PID_EPHRINB_REV_PATHWAY	Ephrin B reverse signaling
0.1	2.3	PID_HEDGEHOG_2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	0.9	SA_REG_CASCADE_OF_CYCLIN_EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	4.2	PID_MYC_REPRESS_PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	3.1	PID_RHOA_PATHWAY	RhoA signaling pathway
0.1	1.8	PID_ATR_PATHWAY	ATR signaling pathway
0.0	0.4	PID_FOXO_PATHWAY	FoxO family signaling
0.0	2.5	PID_PLK1_PATHWAY	PLK1 signaling events
0.0	1.0	PID_FRA_PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	2.1	PID_P75_NTR_PATHWAY	p75(NTR)-mediated signaling
0.0	5.6	NABA_ECM_REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.4	PID_TCR_JNK_PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.4	PID_IL6_7_PATHWAY	IL6-mediated signaling events
0.0	3.1	PID_AR_PATHWAY	Coregulation of Androgen receptor activity
0.0	0.5	PID_HNF3A_PATHWAY	FOXA1 transcription factor network
0.0	1.4	PID_LKB1_PATHWAY	LKB1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	19.4	REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.8	3.1	REACTOME_ETHANOL_OXIDATION	Genes involved in Ethanol oxidation
0.5	6.9	REACTOME_CS_DS_DEGRADATION	Genes involved in CS/DS degradation
0.4	10.3	REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.4	5.6	REACTOME_SIGNALING_BY_EGFR_IN_CANCER	Genes involved in Signaling by EGFR in Cancer
0.3	37.8	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	Genes involved in G alpha (i) signalling events
0.2	2.5	REACTOME_HYALURONAN_METABOLISM	Genes involved in Hyaluronan metabolism
0.1	3.0	REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	4.5	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.1	2.4	REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	3.1	REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	2.9	REACTOME_DARPP_32_EVENTS	Genes involved in DARPP-32 events
0.1	2.8	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	0.9	REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	1.8	REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	2.1	REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.8	REACTOME_MYOGENESIS	Genes involved in Myogenesis
0.0	1.8	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.8	REACTOME_GAP_JUNCTION_DEGRADATION	Genes involved in Gap junction degradation
0.0	0.4	REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.9	REACTOME_G0_AND_EARLY_G1	Genes involved in G0 and Early G1
0.0	4.5	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.4	REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	2.2	REACTOME_MEIOTIC_SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.7	REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.6	REACTOME_PERK_REGULATED_GENE_EXPRESSION	Genes involved in PERK regulated gene expression
0.0	0.5	REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.4	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.3	REACTOME_NUCLEAR_SIGNALING_BY_ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	4.3	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.3	REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION	Genes involved in RNA Polymerase I Transcription Termination

---