Motif ID: Tbx20

Z-value: 0.550


Transcription factors associated with Tbx20:

Gene SymbolEntrez IDGene Name
Tbx20 ENSMUSG00000031965.8 Tbx20



Activity profile for motif Tbx20.

activity profile for motif Tbx20


Sorted Z-values histogram for motif Tbx20

Sorted Z-values for motif Tbx20



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx20

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_53707532 10.753 ENSMUST00000031093.3
 Cckar
cholecystokinin A receptor
chr19_+_38055002 10.307 ENSMUST00000096096.4
ENSMUST00000116506.1
ENSMUST00000169673.1
 Cep55


centrosomal protein 55


chr4_-_118437331 9.675 ENSMUST00000006565.6
 Cdc20
cell division cycle 20
chr7_+_79660196 8.620 ENSMUST00000035977.7
 Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr7_+_114745685 7.693 ENSMUST00000136645.1
ENSMUST00000169913.1
 Insc

inscuteable homolog (Drosophila)

chr6_+_15196949 6.096 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
 Foxp2



forkhead box P2



chr12_+_51348265 3.589 ENSMUST00000119211.1
 G2e3
G2/M-phase specific E3 ubiquitin ligase
chr12_+_51348370 3.512 ENSMUST00000121521.1
 G2e3
G2/M-phase specific E3 ubiquitin ligase
chr8_-_22694061 3.158 ENSMUST00000131767.1
 Ikbkb
inhibitor of kappaB kinase beta
chr7_-_105787567 2.365 ENSMUST00000144189.1
 Dchs1
dachsous 1 (Drosophila)
chr7_-_105787544 2.344 ENSMUST00000078482.5
ENSMUST00000154659.1
 Dchs1

dachsous 1 (Drosophila)

chr2_+_54436317 1.633 ENSMUST00000112636.1
ENSMUST00000112635.1
ENSMUST00000112634.1
 Galnt13


UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13


chr17_-_23745829 1.423 ENSMUST00000046525.8
 Kremen2
kringle containing transmembrane protein 2
chr11_-_86807624 1.378 ENSMUST00000018569.7
 Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr5_-_120777628 1.330 ENSMUST00000044833.8
 Oas3
2'-5' oligoadenylate synthetase 3
chr9_-_73039644 0.934 ENSMUST00000184389.1
 Pigb
phosphatidylinositol glycan anchor biosynthesis, class B
chr9_-_73039697 0.727 ENSMUST00000184035.1
ENSMUST00000098566.4
 Pigb

phosphatidylinositol glycan anchor biosynthesis, class B

chr6_-_122340499 0.613 ENSMUST00000160843.1
 Phc1
polyhomeotic-like 1 (Drosophila)
chr8_-_85555261 0.358 ENSMUST00000034138.5
 Dnaja2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr6_-_122340525 0.311 ENSMUST00000112600.2
 Phc1
polyhomeotic-like 1 (Drosophila)
chr15_-_102516806 0.230 ENSMUST00000169162.1
ENSMUST00000023812.2
ENSMUST00000165174.1
ENSMUST00000169367.1
ENSMUST00000169377.1
 Map3k12




mitogen-activated protein kinase kinase kinase 12




chr8_-_3694167 0.187 ENSMUST00000005678.4
 Fcer2a
Fc receptor, IgE, low affinity II, alpha polypeptide

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
1.4 9.7 GO:0000279 M phase(GO:0000279)
1.2 4.7 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
1.1 8.6 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.6 3.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.6 10.3 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.5 6.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2 7.7 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.2 1.3 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 1.7 GO:0097502 mannosylation(GO:0097502)
0.1 0.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 7.1 GO:0001824 blastocyst development(GO:0001824)
0.0 1.6 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.4 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.4 GO:0042026 protein refolding(GO:0042026)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 10.3 GO:0090543 Flemming body(GO:0090543)
0.4 9.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 3.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.9 GO:0001739 sex chromatin(GO:0001739)
0.1 10.8 GO:0043195 terminal bouton(GO:0043195)
0.0 7.7 GO:0005938 cell cortex(GO:0005938)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.1 3.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 10.8 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 1.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 7.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 6.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 7.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.4 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 9.5 GO:0003682 chromatin binding(GO:0003682)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.7 PID_PLK1_PATHWAY PLK1 signaling events
0.1 3.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.7 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.3 3.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 10.8 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.7 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.6 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.3 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling