Motif ID: Tcf4_Mesp1
Z-value: 2.181
Transcription factors associated with Tcf4_Mesp1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Mesp1 | ENSMUSG00000030544.5 | Mesp1 |
Tcf4 | ENSMUSG00000053477.9 | Tcf4 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tcf4 | mm10_v2_chr18_+_69344503_69344530 | -0.24 | 3.4e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
19.1 | 57.2 | GO:2000111 | cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) |
9.6 | 38.3 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
8.1 | 40.3 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
7.8 | 23.3 | GO:0060596 | mammary placode formation(GO:0060596) |
7.6 | 30.4 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
7.4 | 22.2 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
7.0 | 28.1 | GO:1902512 | positive regulation of apoptotic DNA fragmentation(GO:1902512) |
6.9 | 34.5 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
6.8 | 20.3 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
6.4 | 19.3 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
6.3 | 18.9 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
6.0 | 42.2 | GO:0061092 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
5.3 | 26.7 | GO:0075136 | response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136) |
4.9 | 9.8 | GO:0098917 | retrograde trans-synaptic signaling(GO:0098917) |
4.4 | 26.3 | GO:0046880 | regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884) |
4.2 | 12.7 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) |
4.1 | 12.2 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
4.0 | 12.0 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
3.9 | 11.7 | GO:1900673 | olefin metabolic process(GO:1900673) |
3.9 | 15.5 | GO:0051866 | general adaptation syndrome(GO:0051866) |
3.9 | 7.7 | GO:1902669 | positive regulation of axon guidance(GO:1902669) |
3.8 | 11.4 | GO:0010752 | signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752) |
3.6 | 10.8 | GO:0099548 | trans-synaptic signaling by nitric oxide(GO:0099548) |
3.6 | 10.7 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
3.5 | 10.6 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
3.4 | 10.3 | GO:0006226 | dUMP biosynthetic process(GO:0006226) |
3.4 | 20.1 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
3.3 | 13.1 | GO:1904457 | positive regulation of neuronal action potential(GO:1904457) |
3.2 | 3.2 | GO:0002432 | granuloma formation(GO:0002432) |
3.2 | 19.3 | GO:0014832 | urinary bladder smooth muscle contraction(GO:0014832) |
3.2 | 15.8 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
3.1 | 15.6 | GO:0070327 | thyroid hormone transport(GO:0070327) |
3.1 | 12.5 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
3.0 | 12.2 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
3.0 | 8.9 | GO:0060060 | post-embryonic retina morphogenesis in camera-type eye(GO:0060060) |
3.0 | 8.9 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
2.9 | 8.8 | GO:0043181 | vacuolar sequestering(GO:0043181) |
2.9 | 26.2 | GO:0071420 | cellular response to histamine(GO:0071420) |
2.9 | 11.6 | GO:1990379 | lipid transport across blood brain barrier(GO:1990379) |
2.8 | 8.5 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
2.7 | 16.1 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
2.6 | 92.2 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
2.5 | 12.7 | GO:0036115 | fatty-acyl-CoA catabolic process(GO:0036115) |
2.5 | 7.6 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
2.5 | 15.0 | GO:0032439 | endosome localization(GO:0032439) |
2.5 | 12.4 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
2.4 | 7.3 | GO:0032430 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466) |
2.3 | 11.4 | GO:0060054 | positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) |
2.2 | 9.0 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
2.2 | 6.7 | GO:0001757 | somite specification(GO:0001757) |
2.2 | 8.8 | GO:0035990 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
2.2 | 2.2 | GO:0032276 | regulation of gonadotropin secretion(GO:0032276) |
2.2 | 19.7 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
2.2 | 23.8 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
2.1 | 6.4 | GO:0051892 | negative regulation of cardioblast differentiation(GO:0051892) |
2.1 | 4.3 | GO:0045163 | neuronal ion channel clustering(GO:0045161) clustering of voltage-gated potassium channels(GO:0045163) |
2.1 | 6.4 | GO:0048687 | positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) |
2.1 | 23.1 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
2.1 | 16.4 | GO:0051014 | actin filament severing(GO:0051014) |
2.0 | 14.2 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
2.0 | 29.9 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
2.0 | 2.0 | GO:2000170 | positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170) |
2.0 | 15.7 | GO:0014889 | muscle atrophy(GO:0014889) |
2.0 | 7.8 | GO:0002924 | negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) |
2.0 | 5.9 | GO:0019085 | early viral transcription(GO:0019085) |
1.9 | 11.1 | GO:0032796 | uropod organization(GO:0032796) |
1.8 | 5.5 | GO:1900039 | positive regulation of cellular response to hypoxia(GO:1900039) |
1.8 | 23.7 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
1.8 | 10.9 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
1.8 | 3.6 | GO:0035106 | operant conditioning(GO:0035106) |
1.8 | 5.4 | GO:0015866 | ADP transport(GO:0015866) |
1.8 | 10.8 | GO:0045217 | cell-cell junction maintenance(GO:0045217) |
1.8 | 3.6 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180) |
1.8 | 5.3 | GO:0072720 | cellular response to UV-A(GO:0071492) response to dithiothreitol(GO:0072720) |
1.8 | 7.1 | GO:0090472 | dibasic protein processing(GO:0090472) |
1.8 | 15.9 | GO:0097119 | postsynaptic density protein 95 clustering(GO:0097119) |
1.7 | 6.9 | GO:1904529 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
1.7 | 12.1 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
1.7 | 6.7 | GO:0097211 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
1.7 | 11.8 | GO:0060371 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) |
1.7 | 1.7 | GO:0032847 | regulation of cellular pH reduction(GO:0032847) |
1.6 | 16.4 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
1.6 | 3.3 | GO:0097107 | postsynaptic density assembly(GO:0097107) guanylate kinase-associated protein clustering(GO:0097117) |
1.6 | 4.8 | GO:0016132 | brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132) |
1.6 | 3.2 | GO:0032346 | positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) |
1.6 | 95.3 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
1.6 | 6.3 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
1.6 | 4.7 | GO:0006566 | threonine metabolic process(GO:0006566) |
1.6 | 6.2 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
1.6 | 6.2 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) |
1.5 | 1.5 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) |
1.5 | 9.1 | GO:0098964 | dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964) |
1.5 | 9.1 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
1.5 | 16.0 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
1.4 | 18.8 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
1.4 | 4.3 | GO:0015886 | heme transport(GO:0015886) |
1.4 | 5.5 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
1.4 | 6.8 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
1.4 | 9.5 | GO:0015862 | uridine transport(GO:0015862) |
1.4 | 2.7 | GO:0032910 | transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) |
1.4 | 17.6 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
1.4 | 10.8 | GO:0080184 | response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184) |
1.3 | 8.0 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
1.3 | 2.7 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
1.3 | 5.3 | GO:2000546 | positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
1.3 | 17.3 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
1.3 | 5.3 | GO:0061623 | glycolytic process from galactose(GO:0061623) |
1.3 | 28.7 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
1.3 | 2.6 | GO:2000036 | regulation of stem cell population maintenance(GO:2000036) |
1.3 | 10.4 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
1.3 | 3.8 | GO:0060535 | trachea cartilage morphogenesis(GO:0060535) |
1.3 | 3.8 | GO:0070343 | white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) |
1.3 | 2.5 | GO:0014826 | vein smooth muscle contraction(GO:0014826) |
1.3 | 3.8 | GO:0051715 | cytolysis in other organism(GO:0051715) |
1.2 | 2.5 | GO:0034331 | cell junction maintenance(GO:0034331) |
1.2 | 8.7 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
1.2 | 3.7 | GO:0001661 | conditioned taste aversion(GO:0001661) |
1.2 | 14.8 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
1.2 | 7.4 | GO:0005513 | detection of calcium ion(GO:0005513) |
1.2 | 9.7 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
1.2 | 9.7 | GO:0055089 | fatty acid homeostasis(GO:0055089) |
1.2 | 2.4 | GO:0006990 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) |
1.2 | 2.4 | GO:0086042 | cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) |
1.2 | 3.6 | GO:0042196 | dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197) |
1.2 | 3.6 | GO:0035963 | response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) |
1.2 | 4.7 | GO:0010693 | negative regulation of alkaline phosphatase activity(GO:0010693) |
1.2 | 3.5 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
1.2 | 4.7 | GO:0050913 | sensory perception of bitter taste(GO:0050913) |
1.2 | 3.5 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
1.2 | 4.6 | GO:0050965 | detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965) |
1.1 | 4.6 | GO:0001692 | histamine metabolic process(GO:0001692) |
1.1 | 5.7 | GO:0010626 | negative regulation of Schwann cell proliferation(GO:0010626) |
1.1 | 1.1 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) |
1.1 | 2.3 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
1.1 | 3.4 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
1.1 | 1.1 | GO:0032902 | nerve growth factor production(GO:0032902) |
1.1 | 1.1 | GO:0003011 | diaphragm contraction(GO:0002086) involuntary skeletal muscle contraction(GO:0003011) |
1.1 | 4.4 | GO:0006751 | glutathione catabolic process(GO:0006751) |
1.1 | 2.2 | GO:2000344 | positive regulation of acrosome reaction(GO:2000344) |
1.1 | 6.6 | GO:0050812 | regulation of acyl-CoA biosynthetic process(GO:0050812) |
1.1 | 27.6 | GO:0043496 | regulation of protein homodimerization activity(GO:0043496) |
1.1 | 3.3 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
1.1 | 7.5 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
1.1 | 3.2 | GO:0034035 | sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
1.1 | 2.1 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
1.1 | 3.2 | GO:0003418 | growth plate cartilage chondrocyte differentiation(GO:0003418) |
1.0 | 6.3 | GO:0098967 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
1.0 | 3.1 | GO:2000564 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) |
1.0 | 1.0 | GO:0010046 | response to mycotoxin(GO:0010046) |
1.0 | 4.2 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
1.0 | 9.3 | GO:0032098 | regulation of appetite(GO:0032098) |
1.0 | 2.0 | GO:0050859 | B cell proliferation involved in immune response(GO:0002322) negative regulation of B cell receptor signaling pathway(GO:0050859) |
1.0 | 3.0 | GO:0006578 | amino-acid betaine biosynthetic process(GO:0006578) |
1.0 | 17.8 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
1.0 | 4.0 | GO:0071034 | CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
1.0 | 4.9 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
1.0 | 5.9 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
1.0 | 4.9 | GO:0043129 | surfactant homeostasis(GO:0043129) |
1.0 | 5.9 | GO:0044034 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
1.0 | 2.9 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
1.0 | 8.7 | GO:0007567 | parturition(GO:0007567) |
1.0 | 3.9 | GO:0045054 | constitutive secretory pathway(GO:0045054) |
1.0 | 1.9 | GO:0090649 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
1.0 | 2.9 | GO:0070428 | regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432) |
0.9 | 3.8 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
0.9 | 2.8 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
0.9 | 1.9 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
0.9 | 2.8 | GO:0030974 | thiamine pyrophosphate transport(GO:0030974) |
0.9 | 7.5 | GO:0014824 | artery smooth muscle contraction(GO:0014824) |
0.9 | 3.7 | GO:0006710 | androgen catabolic process(GO:0006710) |
0.9 | 2.8 | GO:1990523 | bone regeneration(GO:1990523) |
0.9 | 5.5 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
0.9 | 2.7 | GO:0046959 | habituation(GO:0046959) |
0.9 | 9.9 | GO:0050909 | sensory perception of taste(GO:0050909) |
0.9 | 2.7 | GO:0010961 | cellular magnesium ion homeostasis(GO:0010961) |
0.9 | 17.6 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.9 | 4.4 | GO:0060120 | auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120) |
0.9 | 5.1 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
0.9 | 5.1 | GO:0015846 | polyamine transport(GO:0015846) |
0.9 | 5.1 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.8 | 4.2 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.8 | 6.8 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.8 | 4.1 | GO:0015803 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
0.8 | 5.7 | GO:0070314 | G1 to G0 transition(GO:0070314) |
0.8 | 1.6 | GO:0098908 | regulation of neuronal action potential(GO:0098908) |
0.8 | 5.6 | GO:0014819 | regulation of skeletal muscle contraction(GO:0014819) |
0.8 | 3.2 | GO:0040010 | positive regulation of growth rate(GO:0040010) |
0.8 | 5.5 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.8 | 3.1 | GO:0007412 | axon target recognition(GO:0007412) |
0.8 | 2.3 | GO:0006083 | acetate metabolic process(GO:0006083) |
0.8 | 39.3 | GO:0034605 | cellular response to heat(GO:0034605) |
0.8 | 4.6 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
0.8 | 3.8 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.8 | 9.8 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
0.8 | 6.8 | GO:0033008 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
0.8 | 2.3 | GO:0060003 | copper ion export(GO:0060003) cellular response to manganese ion(GO:0071287) |
0.7 | 3.0 | GO:0070166 | enamel mineralization(GO:0070166) |
0.7 | 0.7 | GO:0072197 | ureter morphogenesis(GO:0072197) |
0.7 | 6.7 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
0.7 | 3.7 | GO:0050855 | histone-threonine phosphorylation(GO:0035405) regulation of B cell receptor signaling pathway(GO:0050855) positive regulation of B cell receptor signaling pathway(GO:0050861) |
0.7 | 2.2 | GO:0009182 | purine deoxyribonucleotide biosynthetic process(GO:0009153) purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710) |
0.7 | 1.5 | GO:0006059 | hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401) inner medullary collecting duct development(GO:0072061) |
0.7 | 2.9 | GO:0001705 | ectoderm formation(GO:0001705) |
0.7 | 2.2 | GO:1901608 | dense core granule localization(GO:0032253) cellular response to isoquinoline alkaloid(GO:0071317) regulation of vesicle transport along microtubule(GO:1901608) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811) |
0.7 | 2.2 | GO:0006953 | acute-phase response(GO:0006953) |
0.7 | 9.3 | GO:0048681 | negative regulation of axon regeneration(GO:0048681) |
0.7 | 6.4 | GO:0098907 | T-tubule organization(GO:0033292) protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907) |
0.7 | 6.2 | GO:0033623 | regulation of integrin activation(GO:0033623) |
0.7 | 4.8 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
0.7 | 6.2 | GO:0042136 | neurotransmitter biosynthetic process(GO:0042136) |
0.7 | 1.4 | GO:0003100 | regulation of systemic arterial blood pressure by endothelin(GO:0003100) positive regulation of guanylate cyclase activity(GO:0031284) |
0.7 | 2.0 | GO:0061763 | multivesicular body-lysosome fusion(GO:0061763) |
0.7 | 16.4 | GO:0007616 | long-term memory(GO:0007616) |
0.7 | 2.7 | GO:0032788 | saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789) |
0.7 | 1.3 | GO:0070384 | Harderian gland development(GO:0070384) |
0.7 | 2.0 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
0.7 | 2.0 | GO:1903490 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
0.7 | 3.3 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
0.7 | 5.3 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
0.7 | 2.0 | GO:0006435 | threonyl-tRNA aminoacylation(GO:0006435) |
0.6 | 2.6 | GO:0043461 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
0.6 | 1.3 | GO:2000347 | positive regulation of hepatocyte proliferation(GO:2000347) |
0.6 | 2.6 | GO:0034141 | positive regulation of toll-like receptor 3 signaling pathway(GO:0034141) |
0.6 | 1.3 | GO:0036118 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
0.6 | 1.9 | GO:1900369 | negative regulation of RNA interference(GO:1900369) |
0.6 | 2.5 | GO:1903236 | regulation of leukocyte tethering or rolling(GO:1903236) negative regulation of leukocyte tethering or rolling(GO:1903237) |
0.6 | 26.2 | GO:0045022 | early endosome to late endosome transport(GO:0045022) |
0.6 | 1.9 | GO:0051182 | coenzyme transport(GO:0051182) |
0.6 | 4.3 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
0.6 | 1.9 | GO:0098886 | modification of dendritic spine(GO:0098886) |
0.6 | 3.7 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
0.6 | 1.9 | GO:0032274 | gonadotropin secretion(GO:0032274) |
0.6 | 9.9 | GO:0001553 | luteinization(GO:0001553) |
0.6 | 33.2 | GO:0010812 | negative regulation of cell-substrate adhesion(GO:0010812) |
0.6 | 3.7 | GO:0010572 | positive regulation of platelet activation(GO:0010572) |
0.6 | 4.8 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.6 | 4.2 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.6 | 9.1 | GO:0016322 | neuron remodeling(GO:0016322) |
0.6 | 6.0 | GO:2000821 | regulation of grooming behavior(GO:2000821) |
0.6 | 0.6 | GO:0036151 | phosphatidylcholine acyl-chain remodeling(GO:0036151) |
0.6 | 1.7 | GO:0046381 | CMP-N-acetylneuraminate metabolic process(GO:0046381) |
0.6 | 4.0 | GO:0019532 | oxalate transport(GO:0019532) |
0.6 | 1.1 | GO:0060913 | cardiac cell fate determination(GO:0060913) regulation of cardiac cell fate specification(GO:2000043) |
0.6 | 0.6 | GO:1904995 | negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995) |
0.6 | 4.6 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
0.6 | 1.7 | GO:0046416 | D-amino acid metabolic process(GO:0046416) |
0.6 | 4.0 | GO:0019673 | GDP-mannose metabolic process(GO:0019673) |
0.6 | 22.7 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
0.6 | 2.2 | GO:0015888 | thiamine transport(GO:0015888) |
0.6 | 66.1 | GO:0016579 | protein deubiquitination(GO:0016579) |
0.6 | 6.7 | GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314) |
0.6 | 16.1 | GO:0051693 | actin filament capping(GO:0051693) |
0.6 | 1.7 | GO:0045629 | regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629) |
0.5 | 4.4 | GO:0014850 | response to muscle activity(GO:0014850) |
0.5 | 11.5 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
0.5 | 2.7 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
0.5 | 4.9 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
0.5 | 0.5 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
0.5 | 7.0 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
0.5 | 3.2 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
0.5 | 3.7 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
0.5 | 5.3 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.5 | 1.0 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
0.5 | 2.1 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
0.5 | 2.6 | GO:0070197 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
0.5 | 1.0 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.5 | 3.0 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
0.5 | 1.5 | GO:0045763 | negative regulation of cellular amino acid metabolic process(GO:0045763) |
0.5 | 2.0 | GO:0007021 | tubulin complex assembly(GO:0007021) |
0.5 | 6.4 | GO:0042761 | very long-chain fatty acid biosynthetic process(GO:0042761) |
0.5 | 1.5 | GO:1902219 | negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
0.5 | 9.1 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
0.5 | 3.8 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
0.5 | 1.9 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
0.5 | 4.3 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
0.5 | 8.5 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.5 | 1.9 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
0.5 | 3.2 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
0.5 | 1.4 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
0.4 | 13.4 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
0.4 | 12.5 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
0.4 | 3.5 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
0.4 | 0.9 | GO:0031394 | positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
0.4 | 1.8 | GO:2000392 | regulation of lamellipodium morphogenesis(GO:2000392) positive regulation of lamellipodium morphogenesis(GO:2000394) |
0.4 | 3.5 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
0.4 | 7.4 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.4 | 3.0 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
0.4 | 1.3 | GO:0052490 | suppression by virus of host apoptotic process(GO:0019050) negative regulation by symbiont of host apoptotic process(GO:0033668) modulation by virus of host apoptotic process(GO:0039526) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490) positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220) |
0.4 | 22.4 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
0.4 | 11.2 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
0.4 | 1.3 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
0.4 | 4.7 | GO:0061577 | calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) |
0.4 | 3.0 | GO:0007296 | vitellogenesis(GO:0007296) |
0.4 | 2.5 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.4 | 1.3 | GO:0000448 | cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) |
0.4 | 5.4 | GO:0009134 | nucleoside diphosphate catabolic process(GO:0009134) |
0.4 | 3.3 | GO:0071816 | tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
0.4 | 1.2 | GO:1904154 | trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
0.4 | 1.2 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
0.4 | 0.8 | GO:0031642 | negative regulation of myelination(GO:0031642) |
0.4 | 2.4 | GO:0090331 | negative regulation of platelet aggregation(GO:0090331) |
0.4 | 2.4 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
0.4 | 3.6 | GO:0060294 | cilium movement involved in cell motility(GO:0060294) |
0.4 | 0.8 | GO:2000823 | regulation of androgen receptor activity(GO:2000823) |
0.4 | 0.8 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
0.4 | 0.8 | GO:0042636 | negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799) |
0.4 | 2.7 | GO:0015858 | nucleoside transport(GO:0015858) |
0.4 | 0.4 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
0.4 | 1.9 | GO:0008611 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
0.4 | 7.0 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.4 | 1.2 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
0.4 | 3.5 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.4 | 2.3 | GO:0048254 | snoRNA localization(GO:0048254) |
0.4 | 3.8 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
0.4 | 1.5 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.4 | 44.2 | GO:0018107 | peptidyl-threonine phosphorylation(GO:0018107) |
0.4 | 3.8 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.4 | 1.9 | GO:0019236 | response to pheromone(GO:0019236) |
0.4 | 1.5 | GO:0021886 | hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) |
0.4 | 0.7 | GO:0021539 | subthalamus development(GO:0021539) |
0.4 | 9.1 | GO:0007020 | microtubule nucleation(GO:0007020) |
0.4 | 1.1 | GO:0042275 | error-free postreplication DNA repair(GO:0042275) |
0.4 | 1.8 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
0.4 | 2.5 | GO:0060050 | positive regulation of protein glycosylation(GO:0060050) |
0.4 | 2.5 | GO:0042167 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
0.4 | 2.1 | GO:0071625 | vocalization behavior(GO:0071625) |
0.3 | 0.3 | GO:0031590 | wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591) |
0.3 | 2.4 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
0.3 | 0.7 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
0.3 | 2.0 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.3 | 2.4 | GO:0045687 | positive regulation of glial cell differentiation(GO:0045687) |
0.3 | 5.4 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
0.3 | 1.3 | GO:0015786 | UDP-glucose transport(GO:0015786) |
0.3 | 2.3 | GO:0090151 | establishment of protein localization to mitochondrial membrane(GO:0090151) |
0.3 | 2.3 | GO:0033006 | regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304) |
0.3 | 5.6 | GO:0034308 | primary alcohol metabolic process(GO:0034308) |
0.3 | 7.2 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
0.3 | 2.0 | GO:0097186 | amelogenesis(GO:0097186) |
0.3 | 1.0 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
0.3 | 1.0 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.3 | 2.3 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
0.3 | 2.9 | GO:0002347 | response to tumor cell(GO:0002347) |
0.3 | 1.3 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
0.3 | 1.9 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
0.3 | 5.4 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
0.3 | 2.2 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.3 | 0.6 | GO:2001286 | regulation of caveolin-mediated endocytosis(GO:2001286) |
0.3 | 1.3 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
0.3 | 1.9 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
0.3 | 0.9 | GO:2000858 | mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) positive regulation of mineralocorticoid secretion(GO:2000857) regulation of aldosterone secretion(GO:2000858) positive regulation of aldosterone secretion(GO:2000860) |
0.3 | 5.8 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
0.3 | 3.9 | GO:0097284 | hepatocyte apoptotic process(GO:0097284) |
0.3 | 3.9 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
0.3 | 1.8 | GO:0046103 | inosine biosynthetic process(GO:0046103) |
0.3 | 2.4 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
0.3 | 4.5 | GO:0090036 | protein kinase C signaling(GO:0070528) regulation of protein kinase C signaling(GO:0090036) |
0.3 | 0.9 | GO:0006244 | pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223) |
0.3 | 1.2 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
0.3 | 1.5 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
0.3 | 2.1 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
0.3 | 2.3 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
0.3 | 7.6 | GO:0034063 | stress granule assembly(GO:0034063) |
0.3 | 1.7 | GO:0051703 | social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) |
0.3 | 5.5 | GO:0031958 | corticosteroid receptor signaling pathway(GO:0031958) |
0.3 | 1.7 | GO:0010454 | negative regulation of cell fate commitment(GO:0010454) |
0.3 | 0.9 | GO:1904580 | regulation of polynucleotide adenylyltransferase activity(GO:1904245) regulation of intracellular mRNA localization(GO:1904580) |
0.3 | 0.9 | GO:0071918 | urea transmembrane transport(GO:0071918) |
0.3 | 4.0 | GO:0045475 | locomotor rhythm(GO:0045475) |
0.3 | 2.0 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) |
0.3 | 2.0 | GO:0045777 | positive regulation of blood pressure(GO:0045777) |
0.3 | 2.5 | GO:0036065 | fucosylation(GO:0036065) |
0.3 | 1.6 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
0.3 | 2.2 | GO:0097421 | liver regeneration(GO:0097421) |
0.3 | 1.1 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
0.3 | 2.2 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.3 | 1.4 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
0.3 | 34.0 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
0.3 | 1.1 | GO:0036089 | cleavage furrow formation(GO:0036089) |
0.3 | 20.1 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
0.3 | 3.5 | GO:0031102 | neuron projection regeneration(GO:0031102) |
0.3 | 1.9 | GO:0015919 | peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046) |
0.3 | 0.5 | GO:0048341 | paraxial mesoderm formation(GO:0048341) |
0.3 | 3.0 | GO:0033137 | negative regulation of peptidyl-serine phosphorylation(GO:0033137) |
0.3 | 1.1 | GO:0006481 | C-terminal protein methylation(GO:0006481) |
0.3 | 3.2 | GO:0019985 | translesion synthesis(GO:0019985) |
0.3 | 3.2 | GO:0097154 | GABAergic neuron differentiation(GO:0097154) |
0.3 | 1.6 | GO:0001927 | exocyst assembly(GO:0001927) |
0.3 | 1.3 | GO:0003214 | cardiac left ventricle morphogenesis(GO:0003214) |
0.3 | 1.0 | GO:0016264 | gap junction assembly(GO:0016264) |
0.3 | 1.3 | GO:0030948 | negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) |
0.3 | 1.5 | GO:0008214 | protein demethylation(GO:0006482) protein dealkylation(GO:0008214) |
0.3 | 2.8 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
0.2 | 1.7 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
0.2 | 2.0 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
0.2 | 1.0 | GO:0097205 | renal filtration(GO:0097205) |
0.2 | 1.0 | GO:0015871 | choline transport(GO:0015871) |
0.2 | 4.9 | GO:0061098 | positive regulation of protein tyrosine kinase activity(GO:0061098) |
0.2 | 0.7 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.2 | 1.7 | GO:0038171 | cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) |
0.2 | 4.6 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
0.2 | 15.0 | GO:0007405 | neuroblast proliferation(GO:0007405) |
0.2 | 1.9 | GO:0030259 | lipid glycosylation(GO:0030259) |
0.2 | 0.7 | GO:0003356 | regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) |
0.2 | 1.2 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
0.2 | 4.4 | GO:0003334 | keratinocyte development(GO:0003334) |
0.2 | 3.7 | GO:0000338 | protein deneddylation(GO:0000338) |
0.2 | 5.1 | GO:0030318 | melanocyte differentiation(GO:0030318) |
0.2 | 0.5 | GO:0072180 | mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180) |
0.2 | 2.1 | GO:0071236 | cellular response to antibiotic(GO:0071236) |
0.2 | 0.7 | GO:0006101 | citrate metabolic process(GO:0006101) tricarboxylic acid metabolic process(GO:0072350) |
0.2 | 6.9 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
0.2 | 1.3 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002) |
0.2 | 12.7 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
0.2 | 5.0 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
0.2 | 1.3 | GO:0006013 | mannose metabolic process(GO:0006013) |
0.2 | 1.5 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
0.2 | 0.4 | GO:0097212 | lysosomal membrane organization(GO:0097212) |
0.2 | 1.5 | GO:1901798 | positive regulation of signal transduction by p53 class mediator(GO:1901798) |
0.2 | 0.8 | GO:0034138 | toll-like receptor 3 signaling pathway(GO:0034138) |
0.2 | 1.5 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
0.2 | 1.9 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.2 | 1.9 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
0.2 | 0.8 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
0.2 | 0.8 | GO:0006543 | glutamine catabolic process(GO:0006543) |
0.2 | 1.8 | GO:0050995 | negative regulation of lipid catabolic process(GO:0050995) |
0.2 | 4.3 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.2 | 1.0 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
0.2 | 2.2 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
0.2 | 0.4 | GO:0035814 | negative regulation of renal sodium excretion(GO:0035814) |
0.2 | 0.4 | GO:2001023 | regulation of response to drug(GO:2001023) |
0.2 | 5.0 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.2 | 1.4 | GO:0001773 | myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011) |
0.2 | 1.0 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
0.2 | 1.4 | GO:0010884 | positive regulation of lipid storage(GO:0010884) |
0.2 | 13.8 | GO:0035308 | negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308) |
0.2 | 2.5 | GO:0005980 | polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
0.2 | 1.5 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.2 | 1.7 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.2 | 10.3 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.2 | 2.5 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.2 | 1.5 | GO:0001916 | positive regulation of T cell mediated cytotoxicity(GO:0001916) |
0.2 | 0.2 | GO:0097264 | self proteolysis(GO:0097264) |
0.2 | 5.4 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.2 | 1.3 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
0.2 | 1.3 | GO:0071318 | cellular response to ATP(GO:0071318) |
0.2 | 0.9 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
0.2 | 0.7 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
0.2 | 0.9 | GO:0042780 | tRNA 3'-end processing(GO:0042780) |
0.2 | 1.1 | GO:0014898 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898) |
0.2 | 3.0 | GO:0006047 | UDP-N-acetylglucosamine metabolic process(GO:0006047) |
0.2 | 1.8 | GO:0070266 | necroptotic process(GO:0070266) |
0.2 | 1.2 | GO:0032261 | purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) |
0.2 | 2.1 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
0.2 | 1.0 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.2 | 1.7 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
0.2 | 2.4 | GO:0003351 | epithelial cilium movement(GO:0003351) |
0.2 | 1.4 | GO:0009249 | protein lipoylation(GO:0009249) |
0.2 | 2.4 | GO:0006308 | DNA catabolic process(GO:0006308) |
0.2 | 1.5 | GO:0046856 | phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856) |
0.2 | 0.7 | GO:1903748 | negative regulation of establishment of protein localization to mitochondrion(GO:1903748) |
0.2 | 0.7 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
0.2 | 3.6 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.2 | 2.3 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.2 | 4.6 | GO:0070527 | platelet aggregation(GO:0070527) |
0.2 | 0.8 | GO:0006842 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
0.2 | 0.8 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.2 | 1.7 | GO:0006144 | purine nucleobase metabolic process(GO:0006144) |
0.2 | 0.8 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
0.2 | 6.1 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.2 | 4.0 | GO:0015804 | neutral amino acid transport(GO:0015804) |
0.2 | 2.5 | GO:0019835 | cytolysis(GO:0019835) |
0.2 | 2.7 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis(GO:0032469) |
0.2 | 0.2 | GO:0097360 | chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382) |
0.1 | 0.6 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
0.1 | 1.2 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
0.1 | 1.3 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.1 | 2.3 | GO:0044253 | positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253) |
0.1 | 0.7 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
0.1 | 0.9 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
0.1 | 1.7 | GO:0006509 | membrane protein ectodomain proteolysis(GO:0006509) |
0.1 | 0.1 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) endocardial cushion to mesenchymal transition(GO:0090500) |
0.1 | 1.0 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.1 | 2.8 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
0.1 | 5.6 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.1 | 2.0 | GO:0042417 | dopamine metabolic process(GO:0042417) |
0.1 | 0.8 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
0.1 | 0.5 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
0.1 | 2.5 | GO:0006754 | ATP biosynthetic process(GO:0006754) |
0.1 | 10.6 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.1 | 3.5 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
0.1 | 1.6 | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) |
0.1 | 1.2 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
0.1 | 1.6 | GO:0048636 | positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863) |
0.1 | 1.3 | GO:0097286 | iron ion import(GO:0097286) |
0.1 | 0.2 | GO:0003180 | aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180) |
0.1 | 0.5 | GO:0046596 | regulation of viral entry into host cell(GO:0046596) |
0.1 | 0.5 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
0.1 | 0.1 | GO:0032429 | regulation of phospholipase A2 activity(GO:0032429) |
0.1 | 6.9 | GO:0045089 | positive regulation of innate immune response(GO:0045089) |
0.1 | 0.3 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
0.1 | 0.3 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
0.1 | 1.7 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
0.1 | 1.0 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.1 | 0.5 | GO:0044130 | negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146) |
0.1 | 2.0 | GO:1901216 | positive regulation of neuron death(GO:1901216) |
0.1 | 2.3 | GO:1901655 | cellular response to ketone(GO:1901655) |
0.1 | 0.3 | GO:0001955 | blood vessel maturation(GO:0001955) |
0.1 | 0.8 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
0.1 | 5.7 | GO:0048709 | oligodendrocyte differentiation(GO:0048709) |
0.1 | 0.6 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
0.1 | 1.3 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
0.1 | 2.1 | GO:0032933 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
0.1 | 0.5 | GO:0043045 | DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538) |
0.1 | 0.3 | GO:0060217 | positive regulation of chromatin assembly or disassembly(GO:0045799) hemangioblast cell differentiation(GO:0060217) |
0.1 | 1.7 | GO:0045921 | positive regulation of exocytosis(GO:0045921) |
0.1 | 0.9 | GO:0031047 | gene silencing by RNA(GO:0031047) |
0.1 | 0.3 | GO:0097298 | regulation of nucleus size(GO:0097298) |
0.1 | 2.3 | GO:0043507 | positive regulation of JUN kinase activity(GO:0043507) |
0.1 | 5.1 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.1 | 0.5 | GO:0008053 | mitochondrial fusion(GO:0008053) |
0.1 | 1.2 | GO:0002021 | response to dietary excess(GO:0002021) |
0.1 | 0.6 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
0.1 | 0.6 | GO:0048520 | positive regulation of behavior(GO:0048520) |
0.1 | 1.8 | GO:2000785 | regulation of autophagosome assembly(GO:2000785) |
0.1 | 1.7 | GO:0035690 | cellular response to drug(GO:0035690) |
0.1 | 1.3 | GO:0010718 | positive regulation of epithelial to mesenchymal transition(GO:0010718) |
0.1 | 3.9 | GO:0015992 | proton transport(GO:0015992) |
0.1 | 0.6 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
0.1 | 0.3 | GO:0045776 | negative regulation of blood pressure(GO:0045776) |
0.1 | 1.5 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.1 | 1.0 | GO:1902743 | regulation of lamellipodium organization(GO:1902743) |
0.1 | 0.4 | GO:0044241 | lipid digestion(GO:0044241) |
0.1 | 0.4 | GO:0014002 | astrocyte development(GO:0014002) |
0.1 | 0.4 | GO:0035115 | embryonic forelimb morphogenesis(GO:0035115) |
0.1 | 0.6 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
0.1 | 0.3 | GO:0032757 | positive regulation of interleukin-8 production(GO:0032757) |
0.1 | 0.3 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
0.1 | 0.5 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
0.1 | 0.5 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
0.1 | 0.9 | GO:0045760 | positive regulation of action potential(GO:0045760) |
0.1 | 0.4 | GO:1901911 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
0.1 | 0.8 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
0.1 | 1.8 | GO:0031062 | positive regulation of histone methylation(GO:0031062) |
0.1 | 0.4 | GO:0045648 | positive regulation of erythrocyte differentiation(GO:0045648) |
0.1 | 0.9 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
0.1 | 0.1 | GO:0032074 | negative regulation of nuclease activity(GO:0032074) |
0.1 | 7.7 | GO:0050890 | cognition(GO:0050890) |
0.1 | 0.3 | GO:0033313 | meiotic cell cycle checkpoint(GO:0033313) |
0.1 | 0.3 | GO:0060292 | long term synaptic depression(GO:0060292) |
0.1 | 0.3 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) |
0.1 | 0.4 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
0.1 | 2.3 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
0.1 | 0.8 | GO:0006515 | misfolded or incompletely synthesized protein catabolic process(GO:0006515) |
0.0 | 2.1 | GO:0034341 | response to interferon-gamma(GO:0034341) |
0.0 | 0.5 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
0.0 | 0.1 | GO:0010820 | positive regulation of T cell chemotaxis(GO:0010820) |
0.0 | 0.1 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
0.0 | 0.1 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
0.0 | 0.7 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.0 | 0.1 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
0.0 | 0.1 | GO:1900060 | negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060) |
0.0 | 0.3 | GO:0035767 | endothelial cell chemotaxis(GO:0035767) |
0.0 | 0.1 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
0.0 | 0.8 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
0.0 | 0.7 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
0.0 | 0.3 | GO:0006301 | postreplication repair(GO:0006301) |
0.0 | 0.4 | GO:0043921 | modulation by host of viral transcription(GO:0043921) modulation of transcription in other organism involved in symbiotic interaction(GO:0052312) modulation by host of symbiont transcription(GO:0052472) |
0.0 | 0.2 | GO:0006108 | malate metabolic process(GO:0006108) |
0.0 | 0.8 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
0.0 | 0.7 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
0.0 | 0.3 | GO:0016486 | peptide hormone processing(GO:0016486) |
0.0 | 0.3 | GO:0002566 | somatic diversification of immune receptors via somatic mutation(GO:0002566) |
0.0 | 0.1 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
0.0 | 0.5 | GO:0051180 | vitamin transport(GO:0051180) |
0.0 | 0.8 | GO:0030488 | tRNA methylation(GO:0030488) |
0.0 | 0.4 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
0.0 | 0.1 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
0.0 | 0.1 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
0.0 | 0.2 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
0.0 | 0.1 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
0.0 | 0.1 | GO:0009313 | oligosaccharide catabolic process(GO:0009313) |
0.0 | 0.5 | GO:0003382 | epithelial cell morphogenesis(GO:0003382) |
0.0 | 1.0 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
0.0 | 3.7 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
0.0 | 0.3 | GO:0006896 | Golgi to vacuole transport(GO:0006896) |
0.0 | 0.6 | GO:0042775 | mitochondrial ATP synthesis coupled electron transport(GO:0042775) |
0.0 | 0.5 | GO:1903427 | negative regulation of reactive oxygen species biosynthetic process(GO:1903427) |
0.0 | 0.5 | GO:0009303 | rRNA transcription(GO:0009303) |
0.0 | 0.1 | GO:0097300 | programmed necrotic cell death(GO:0097300) |
0.0 | 0.2 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
0.0 | 0.2 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
0.0 | 0.3 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
0.0 | 0.6 | GO:0006040 | amino sugar metabolic process(GO:0006040) |
0.0 | 0.8 | GO:0006611 | protein export from nucleus(GO:0006611) |
0.0 | 0.0 | GO:0060768 | epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) |
0.0 | 0.2 | GO:0045879 | negative regulation of smoothened signaling pathway(GO:0045879) |
0.0 | 0.2 | GO:0090231 | regulation of spindle checkpoint(GO:0090231) |
0.0 | 0.1 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.0 | 0.2 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
0.0 | 0.5 | GO:0006414 | translational elongation(GO:0006414) |
0.0 | 0.0 | GO:0060155 | platelet dense granule organization(GO:0060155) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
8.8 | 26.3 | GO:0043512 | inhibin A complex(GO:0043512) |
6.7 | 27.0 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
6.7 | 20.2 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
5.6 | 22.2 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
4.4 | 17.5 | GO:1990769 | proximal neuron projection(GO:1990769) |
4.1 | 12.2 | GO:0005940 | septin ring(GO:0005940) |
3.7 | 21.9 | GO:0008091 | spectrin(GO:0008091) |
3.5 | 20.8 | GO:0045179 | apical cortex(GO:0045179) |
2.9 | 11.4 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
2.8 | 11.0 | GO:0044307 | dendritic branch(GO:0044307) |
2.7 | 5.5 | GO:0044305 | calyx of Held(GO:0044305) |
2.7 | 8.0 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
2.6 | 13.1 | GO:0044316 | cone cell pedicle(GO:0044316) |
2.6 | 7.8 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
2.6 | 5.2 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
2.6 | 33.2 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
2.3 | 20.4 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
2.2 | 42.5 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
2.1 | 35.8 | GO:0032279 | asymmetric synapse(GO:0032279) |
2.0 | 20.1 | GO:0032591 | dendritic spine membrane(GO:0032591) |
1.9 | 9.7 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
1.9 | 13.3 | GO:0070695 | FHF complex(GO:0070695) |
1.9 | 27.9 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
1.8 | 23.9 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
1.7 | 8.7 | GO:0036449 | microtubule minus-end(GO:0036449) |
1.7 | 17.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
1.7 | 13.9 | GO:0097433 | dense body(GO:0097433) |
1.7 | 48.4 | GO:0033268 | node of Ranvier(GO:0033268) |
1.5 | 9.3 | GO:0032807 | DNA ligase IV complex(GO:0032807) |
1.5 | 7.6 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
1.5 | 7.5 | GO:0001533 | cornified envelope(GO:0001533) |
1.5 | 4.4 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
1.5 | 21.9 | GO:0043196 | varicosity(GO:0043196) |
1.5 | 11.7 | GO:0033269 | internode region of axon(GO:0033269) |
1.4 | 37.4 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
1.4 | 8.3 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
1.3 | 5.1 | GO:0031084 | BLOC-2 complex(GO:0031084) |
1.2 | 19.8 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
1.2 | 4.9 | GO:0045098 | type III intermediate filament(GO:0045098) |
1.2 | 6.0 | GO:1990357 | terminal web(GO:1990357) |
1.2 | 1.2 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
1.2 | 5.9 | GO:0030314 | junctional membrane complex(GO:0030314) |
1.2 | 11.7 | GO:0043083 | synaptic cleft(GO:0043083) |
1.1 | 171.8 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
1.1 | 9.1 | GO:0090533 | cation-transporting ATPase complex(GO:0090533) |
1.1 | 3.3 | GO:0071953 | elastic fiber(GO:0071953) |
1.1 | 12.1 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
1.1 | 3.2 | GO:0005921 | gap junction(GO:0005921) |
1.0 | 16.5 | GO:0097431 | mitotic spindle pole(GO:0097431) |
1.0 | 16.5 | GO:0031045 | dense core granule(GO:0031045) |
1.0 | 10.6 | GO:0032426 | stereocilium tip(GO:0032426) |
1.0 | 17.3 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
0.9 | 1.9 | GO:0097444 | spine apparatus(GO:0097444) |
0.8 | 3.3 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
0.8 | 27.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.8 | 7.4 | GO:0005915 | zonula adherens(GO:0005915) |
0.8 | 2.4 | GO:0034657 | GID complex(GO:0034657) |
0.8 | 18.0 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.8 | 12.3 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
0.8 | 3.8 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.7 | 10.4 | GO:0005614 | interstitial matrix(GO:0005614) |
0.7 | 1.5 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
0.7 | 2.9 | GO:0031310 | integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310) |
0.7 | 3.6 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.7 | 6.5 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.7 | 2.9 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
0.7 | 2.1 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
0.7 | 2.1 | GO:0005927 | muscle tendon junction(GO:0005927) cuticular plate(GO:0032437) |
0.7 | 29.3 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.7 | 3.3 | GO:0043194 | axon initial segment(GO:0043194) |
0.7 | 2.6 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.6 | 3.9 | GO:0005796 | Golgi lumen(GO:0005796) |
0.6 | 1.9 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
0.6 | 4.3 | GO:0005638 | lamin filament(GO:0005638) |
0.6 | 8.5 | GO:0005922 | connexon complex(GO:0005922) |
0.6 | 1.2 | GO:0019815 | B cell receptor complex(GO:0019815) |
0.6 | 1.8 | GO:0014802 | terminal cisterna(GO:0014802) |
0.6 | 8.6 | GO:0042555 | MCM complex(GO:0042555) |
0.6 | 11.2 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.6 | 28.2 | GO:0031901 | early endosome membrane(GO:0031901) |
0.5 | 3.7 | GO:0030139 | endocytic vesicle(GO:0030139) |
0.5 | 3.7 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
0.5 | 3.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.5 | 2.0 | GO:0005745 | m-AAA complex(GO:0005745) |
0.5 | 1.0 | GO:0034667 | integrin alpha3-beta1 complex(GO:0034667) |
0.5 | 16.8 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.5 | 1.5 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
0.5 | 8.3 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.5 | 2.4 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
0.5 | 34.2 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.5 | 16.5 | GO:0098794 | postsynapse(GO:0098794) |
0.5 | 2.3 | GO:0097524 | sperm plasma membrane(GO:0097524) |
0.5 | 5.1 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
0.5 | 3.7 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.4 | 1.8 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
0.4 | 2.7 | GO:0035976 | AP1 complex(GO:0035976) |
0.4 | 22.9 | GO:0014704 | intercalated disc(GO:0014704) |
0.4 | 2.6 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.4 | 53.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.4 | 1.3 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
0.4 | 2.6 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.4 | 5.5 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.4 | 15.3 | GO:0005581 | collagen trimer(GO:0005581) |
0.4 | 2.0 | GO:0033270 | paranode region of axon(GO:0033270) |
0.4 | 21.3 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.4 | 5.6 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.4 | 17.0 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.4 | 14.1 | GO:0044295 | axonal growth cone(GO:0044295) |
0.4 | 63.5 | GO:0030016 | myofibril(GO:0030016) |
0.4 | 11.2 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.4 | 1.5 | GO:1990130 | Iml1 complex(GO:1990130) |
0.4 | 2.3 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
0.4 | 70.5 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.4 | 4.5 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.4 | 2.6 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.4 | 3.3 | GO:0044754 | secondary lysosome(GO:0005767) autolysosome(GO:0044754) |
0.4 | 24.5 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.4 | 12.6 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.3 | 1.0 | GO:0016939 | kinesin II complex(GO:0016939) |
0.3 | 2.6 | GO:0030128 | clathrin coat of endocytic vesicle(GO:0030128) endocytic vesicle membrane(GO:0030666) clathrin-coated endocytic vesicle membrane(GO:0030669) |
0.3 | 1.0 | GO:0098855 | HCN channel complex(GO:0098855) |
0.3 | 1.3 | GO:0031021 | interphase microtubule organizing center(GO:0031021) |
0.3 | 2.5 | GO:0033391 | chromatoid body(GO:0033391) |
0.3 | 1.9 | GO:1990393 | 3M complex(GO:1990393) |
0.3 | 3.1 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.3 | 5.8 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.3 | 4.7 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.3 | 3.5 | GO:1990635 | proximal dendrite(GO:1990635) |
0.3 | 1.8 | GO:0000322 | storage vacuole(GO:0000322) |
0.3 | 5.6 | GO:0045178 | basal part of cell(GO:0045178) |
0.3 | 2.0 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
0.3 | 3.1 | GO:0005640 | nuclear outer membrane(GO:0005640) |
0.3 | 21.8 | GO:0043204 | perikaryon(GO:0043204) |
0.3 | 0.8 | GO:0044326 | dendritic spine neck(GO:0044326) |
0.3 | 0.5 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
0.3 | 46.1 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.3 | 5.6 | GO:0005903 | brush border(GO:0005903) |
0.3 | 5.1 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.2 | 3.7 | GO:0000124 | SAGA complex(GO:0000124) |
0.2 | 5.8 | GO:0001772 | immunological synapse(GO:0001772) |
0.2 | 4.6 | GO:0044306 | neuron projection terminus(GO:0044306) |
0.2 | 0.9 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.2 | 5.2 | GO:0097440 | apical dendrite(GO:0097440) |
0.2 | 3.7 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
0.2 | 0.8 | GO:1902636 | kinocilium(GO:0060091) kinociliary basal body(GO:1902636) |
0.2 | 1.7 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.2 | 2.3 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.2 | 2.1 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.2 | 2.8 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.2 | 2.6 | GO:0030008 | TRAPP complex(GO:0030008) |
0.2 | 1.6 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
0.2 | 0.7 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
0.2 | 1.8 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.2 | 1.2 | GO:1990204 | oxidoreductase complex(GO:1990204) |
0.2 | 3.4 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.2 | 2.3 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.2 | 4.8 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
0.2 | 2.1 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.2 | 1.9 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
0.2 | 21.1 | GO:0001650 | fibrillar center(GO:0001650) |
0.2 | 0.6 | GO:0016342 | catenin complex(GO:0016342) |
0.2 | 2.0 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.1 | 23.2 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
0.1 | 0.6 | GO:0097255 | R2TP complex(GO:0097255) |
0.1 | 1.5 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
0.1 | 2.7 | GO:0005686 | U2 snRNP(GO:0005686) |
0.1 | 0.9 | GO:0070765 | gamma-secretase complex(GO:0070765) |
0.1 | 0.4 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
0.1 | 0.7 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.1 | 8.3 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.1 | 13.2 | GO:0044420 | extracellular matrix component(GO:0044420) |
0.1 | 8.6 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.1 | 0.6 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
0.1 | 3.1 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.1 | 1.6 | GO:0031527 | filopodium membrane(GO:0031527) |
0.1 | 0.6 | GO:0097361 | CIA complex(GO:0097361) |
0.1 | 1.2 | GO:0005902 | microvillus(GO:0005902) |
0.1 | 0.6 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.1 | 3.2 | GO:1990752 | microtubule plus-end(GO:0035371) microtubule end(GO:1990752) |
0.1 | 1.3 | GO:0000974 | Prp19 complex(GO:0000974) |
0.1 | 1.4 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.1 | 2.3 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.1 | 1.1 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
0.1 | 4.1 | GO:0031526 | brush border membrane(GO:0031526) |
0.1 | 1.9 | GO:0035102 | PRC1 complex(GO:0035102) |
0.1 | 1.7 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.1 | 10.5 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
0.1 | 1.4 | GO:0097060 | synaptic membrane(GO:0097060) |
0.1 | 0.3 | GO:0070552 | BRISC complex(GO:0070552) |
0.1 | 0.6 | GO:0001891 | phagocytic cup(GO:0001891) |
0.1 | 0.9 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
0.1 | 0.2 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
0.1 | 0.6 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.1 | 0.3 | GO:0033193 | Lsd1/2 complex(GO:0033193) |
0.1 | 2.1 | GO:0043195 | terminal bouton(GO:0043195) |
0.1 | 6.4 | GO:0070382 | exocytic vesicle(GO:0070382) |
0.1 | 2.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.1 | 2.0 | GO:0097546 | ciliary base(GO:0097546) |
0.1 | 0.3 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
0.1 | 1.1 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.1 | 7.2 | GO:0034702 | ion channel complex(GO:0034702) |
0.1 | 4.3 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.1 | 0.4 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
0.1 | 0.2 | GO:0036128 | CatSper complex(GO:0036128) |
0.1 | 10.9 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
0.1 | 2.4 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.1 | 0.3 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.1 | 0.9 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 0.8 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.1 | 0.2 | GO:0000814 | ESCRT II complex(GO:0000814) |
0.1 | 2.0 | GO:0032592 | integral component of mitochondrial membrane(GO:0032592) |
0.1 | 0.3 | GO:0042629 | mast cell granule(GO:0042629) |
0.1 | 1.8 | GO:0032587 | ruffle membrane(GO:0032587) |
0.1 | 0.2 | GO:0048179 | activin receptor complex(GO:0048179) |
0.0 | 0.5 | GO:0030914 | STAGA complex(GO:0030914) |
0.0 | 1.2 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.0 | 0.1 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 0.4 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.0 | 0.1 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
0.0 | 0.4 | GO:0043235 | receptor complex(GO:0043235) |
0.0 | 0.1 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
0.0 | 0.5 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.0 | 0.8 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
0.0 | 1.2 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
0.0 | 0.1 | GO:0035339 | SPOTS complex(GO:0035339) |
0.0 | 0.2 | GO:0046930 | pore complex(GO:0046930) |
0.0 | 0.3 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
0.0 | 0.9 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 3.5 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.0 | 3.8 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
0.0 | 0.2 | GO:0030677 | ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681) |
0.0 | 0.7 | GO:0016234 | inclusion body(GO:0016234) |
0.0 | 0.2 | GO:0016272 | prefoldin complex(GO:0016272) |
0.0 | 0.2 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 0.3 | GO:0030686 | 90S preribosome(GO:0030686) |
0.0 | 0.7 | GO:0043197 | dendritic spine(GO:0043197) |
0.0 | 1.0 | GO:0044297 | cell body(GO:0044297) |
0.0 | 0.2 | GO:0000145 | exocyst(GO:0000145) |
0.0 | 0.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.0 | 0.1 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
8.7 | 60.8 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
6.9 | 34.5 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
5.4 | 26.9 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
5.3 | 21.0 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
4.9 | 39.5 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
4.8 | 24.2 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
4.6 | 13.7 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
4.4 | 52.4 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
3.9 | 23.6 | GO:0070699 | type II activin receptor binding(GO:0070699) |
3.6 | 57.7 | GO:0003680 | AT DNA binding(GO:0003680) |
3.3 | 10.0 | GO:0004686 | elongation factor-2 kinase activity(GO:0004686) |
3.3 | 9.9 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
3.3 | 9.9 | GO:0008527 | taste receptor activity(GO:0008527) |
2.9 | 8.8 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
2.9 | 17.4 | GO:0045340 | mercury ion binding(GO:0045340) |
2.9 | 31.7 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
2.8 | 19.9 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
2.6 | 18.4 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
2.6 | 102.1 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
2.6 | 7.8 | GO:0046911 | hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
2.6 | 15.6 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
2.6 | 15.6 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
2.6 | 7.7 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
2.5 | 7.6 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
2.4 | 91.5 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
2.3 | 6.9 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
2.3 | 6.9 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
2.3 | 11.5 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
2.3 | 2.3 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
2.2 | 17.8 | GO:0016312 | inositol bisphosphate phosphatase activity(GO:0016312) |
2.2 | 6.6 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
2.0 | 35.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
1.9 | 11.7 | GO:1904315 | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
1.9 | 9.7 | GO:0035174 | histone serine kinase activity(GO:0035174) |
1.8 | 16.4 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
1.8 | 5.4 | GO:0015228 | coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122) |
1.8 | 12.5 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
1.8 | 5.3 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
1.8 | 14.1 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
1.7 | 6.8 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
1.7 | 42.1 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
1.7 | 11.8 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
1.7 | 20.0 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
1.7 | 6.6 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
1.6 | 19.7 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
1.6 | 9.7 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
1.6 | 4.8 | GO:0009918 | sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598) |
1.6 | 4.7 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
1.6 | 10.9 | GO:1903136 | cuprous ion binding(GO:1903136) |
1.5 | 23.3 | GO:0045499 | chemorepellent activity(GO:0045499) |
1.5 | 7.3 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
1.4 | 4.3 | GO:0015232 | heme transporter activity(GO:0015232) |
1.4 | 11.2 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
1.4 | 18.0 | GO:0005522 | profilin binding(GO:0005522) |
1.3 | 6.7 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
1.3 | 4.0 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
1.3 | 7.9 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
1.3 | 5.3 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
1.3 | 53.7 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
1.3 | 11.7 | GO:0070324 | thyroid hormone binding(GO:0070324) |
1.3 | 43.6 | GO:0030552 | cAMP binding(GO:0030552) |
1.2 | 3.7 | GO:0051538 | 3 iron, 4 sulfur cluster binding(GO:0051538) |
1.2 | 6.2 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
1.2 | 11.2 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
1.2 | 3.7 | GO:0034597 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
1.2 | 3.6 | GO:0019120 | hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651) |
1.2 | 3.5 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
1.2 | 25.9 | GO:0030506 | ankyrin binding(GO:0030506) |
1.2 | 3.5 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
1.2 | 6.9 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
1.1 | 16.0 | GO:0030955 | potassium ion binding(GO:0030955) |
1.1 | 3.3 | GO:0097016 | L27 domain binding(GO:0097016) |
1.1 | 12.3 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
1.1 | 9.7 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
1.1 | 3.2 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
1.1 | 6.3 | GO:0023029 | MHC class Ib protein binding(GO:0023029) |
1.0 | 16.1 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
1.0 | 4.0 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
1.0 | 4.9 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
1.0 | 5.9 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
1.0 | 8.7 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
0.9 | 3.8 | GO:0042834 | peptidoglycan binding(GO:0042834) |
0.9 | 13.2 | GO:0031005 | filamin binding(GO:0031005) |
0.9 | 8.4 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.9 | 18.5 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.9 | 9.2 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.9 | 14.6 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.9 | 1.8 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.9 | 3.6 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
0.9 | 2.7 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
0.9 | 1.8 | GO:0030549 | acetylcholine receptor activator activity(GO:0030549) |
0.9 | 5.3 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
0.9 | 4.3 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
0.8 | 3.4 | GO:0070012 | oligopeptidase activity(GO:0070012) |
0.8 | 5.9 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
0.8 | 2.5 | GO:0004962 | endothelin receptor activity(GO:0004962) |
0.8 | 10.0 | GO:0001618 | virus receptor activity(GO:0001618) |
0.8 | 24.7 | GO:0042805 | actinin binding(GO:0042805) |
0.8 | 4.9 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.8 | 8.2 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.8 | 3.3 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.8 | 33.0 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.8 | 17.5 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.8 | 4.0 | GO:0042979 | ornithine decarboxylase regulator activity(GO:0042979) |
0.8 | 4.7 | GO:0042731 | PH domain binding(GO:0042731) |
0.8 | 3.1 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
0.8 | 6.8 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
0.8 | 71.3 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
0.7 | 5.2 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
0.7 | 3.7 | GO:0035184 | histone threonine kinase activity(GO:0035184) |
0.7 | 3.7 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.7 | 1.5 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
0.7 | 16.6 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.7 | 10.1 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
0.7 | 5.7 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
0.7 | 2.1 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
0.7 | 20.6 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.7 | 4.2 | GO:0033691 | sialic acid binding(GO:0033691) |
0.7 | 9.1 | GO:0099604 | calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604) |
0.7 | 4.2 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
0.7 | 3.5 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
0.7 | 9.7 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.7 | 2.8 | GO:0003696 | satellite DNA binding(GO:0003696) |
0.7 | 4.1 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.7 | 8.2 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.7 | 3.3 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
0.7 | 11.2 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
0.7 | 2.0 | GO:0004829 | threonine-tRNA ligase activity(GO:0004829) |
0.6 | 4.5 | GO:0034711 | inhibin binding(GO:0034711) |
0.6 | 1.3 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.6 | 2.6 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
0.6 | 24.4 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.6 | 8.3 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.6 | 2.5 | GO:0008184 | glycogen phosphorylase activity(GO:0008184) |
0.6 | 8.8 | GO:0005003 | ephrin receptor activity(GO:0005003) |
0.6 | 20.1 | GO:0050699 | WW domain binding(GO:0050699) |
0.6 | 2.5 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
0.6 | 2.5 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
0.6 | 5.0 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.6 | 1.9 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
0.6 | 6.2 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.6 | 16.3 | GO:0003785 | actin monomer binding(GO:0003785) |
0.6 | 14.2 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.6 | 3.0 | GO:0008761 | UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) |
0.6 | 1.7 | GO:0030172 | troponin C binding(GO:0030172) |
0.6 | 5.2 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.6 | 20.1 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.6 | 7.4 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
0.6 | 1.7 | GO:0036361 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
0.6 | 8.0 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.6 | 8.5 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
0.6 | 9.1 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.6 | 8.5 | GO:0036442 | hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.6 | 1.7 | GO:0097677 | STAT family protein binding(GO:0097677) |
0.6 | 12.2 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
0.5 | 2.2 | GO:0004064 | arylesterase activity(GO:0004064) |
0.5 | 6.0 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.5 | 25.9 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
0.5 | 2.1 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
0.5 | 2.1 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
0.5 | 2.1 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
0.5 | 3.5 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.5 | 5.0 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.5 | 3.5 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.5 | 1.0 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
0.5 | 3.9 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
0.5 | 3.4 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
0.5 | 28.3 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.5 | 4.3 | GO:0016151 | nickel cation binding(GO:0016151) |
0.5 | 21.3 | GO:0005516 | calmodulin binding(GO:0005516) |
0.5 | 1.9 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.5 | 2.8 | GO:0015234 | thiamine transmembrane transporter activity(GO:0015234) |
0.5 | 20.9 | GO:0030507 | spectrin binding(GO:0030507) |
0.5 | 1.4 | GO:0016979 | lipoate-protein ligase activity(GO:0016979) |
0.5 | 5.0 | GO:0004622 | lysophospholipase activity(GO:0004622) |
0.5 | 1.4 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
0.4 | 13.9 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.4 | 0.4 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
0.4 | 0.9 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.4 | 7.1 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.4 | 6.6 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.4 | 2.2 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
0.4 | 9.1 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.4 | 1.3 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.4 | 1.3 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
0.4 | 1.7 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
0.4 | 3.0 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.4 | 11.8 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.4 | 12.2 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.4 | 2.5 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
0.4 | 1.3 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
0.4 | 23.1 | GO:0019213 | deacetylase activity(GO:0019213) |
0.4 | 1.6 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
0.4 | 1.2 | GO:0004568 | chitinase activity(GO:0004568) |
0.4 | 3.2 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
0.4 | 2.4 | GO:0005042 | netrin receptor activity(GO:0005042) |
0.4 | 8.3 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.4 | 16.0 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.4 | 2.7 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
0.4 | 3.5 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
0.4 | 3.1 | GO:0035591 | signaling adaptor activity(GO:0035591) |
0.4 | 2.3 | GO:0070403 | NAD+ binding(GO:0070403) |
0.4 | 2.7 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
0.4 | 5.0 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.4 | 2.3 | GO:0050897 | cobalt ion binding(GO:0050897) |
0.4 | 1.5 | GO:0008948 | oxaloacetate decarboxylase activity(GO:0008948) |
0.4 | 0.4 | GO:0008061 | chitin binding(GO:0008061) |
0.4 | 3.3 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.4 | 4.0 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
0.4 | 15.4 | GO:0019894 | kinesin binding(GO:0019894) |
0.4 | 10.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.4 | 1.4 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.3 | 1.0 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
0.3 | 2.4 | GO:0000150 | recombinase activity(GO:0000150) |
0.3 | 5.4 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
0.3 | 6.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.3 | 7.6 | GO:0016769 | transferase activity, transferring nitrogenous groups(GO:0016769) |
0.3 | 2.3 | GO:0030911 | TPR domain binding(GO:0030911) |
0.3 | 3.9 | GO:1990459 | transferrin receptor binding(GO:1990459) |
0.3 | 4.9 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
0.3 | 1.0 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.3 | 1.6 | GO:0008199 | ferroxidase activity(GO:0004322) ferric iron binding(GO:0008199) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.3 | 4.7 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.3 | 19.1 | GO:0005518 | collagen binding(GO:0005518) |
0.3 | 0.3 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
0.3 | 20.3 | GO:0051117 | ATPase binding(GO:0051117) |
0.3 | 1.2 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
0.3 | 2.0 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
0.3 | 3.1 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
0.3 | 8.2 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.3 | 5.8 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.3 | 1.6 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.3 | 1.9 | GO:0032184 | SUMO polymer binding(GO:0032184) |
0.3 | 1.0 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.3 | 5.5 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.3 | 1.8 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.3 | 6.1 | GO:0035254 | glutamate receptor binding(GO:0035254) |
0.3 | 3.3 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.3 | 1.8 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
0.2 | 15.1 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.2 | 2.4 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
0.2 | 3.1 | GO:0005521 | lamin binding(GO:0005521) |
0.2 | 4.1 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.2 | 6.3 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.2 | 1.2 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
0.2 | 1.9 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
0.2 | 2.3 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
0.2 | 2.1 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.2 | 4.3 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.2 | 6.3 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
0.2 | 6.6 | GO:0008009 | chemokine activity(GO:0008009) |
0.2 | 2.7 | GO:0048018 | receptor agonist activity(GO:0048018) |
0.2 | 1.7 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
0.2 | 9.4 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.2 | 0.6 | GO:0008176 | tRNA (guanine-N7-)-methyltransferase activity(GO:0008176) |
0.2 | 2.3 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.2 | 10.2 | GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627) |
0.2 | 1.2 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.2 | 1.0 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
0.2 | 1.1 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.2 | 3.0 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.2 | 2.1 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
0.2 | 5.8 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.2 | 3.0 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.2 | 0.7 | GO:0070404 | NADH binding(GO:0070404) |
0.2 | 1.3 | GO:0051731 | polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) |
0.2 | 5.1 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.2 | 0.7 | GO:0016453 | acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453) |
0.2 | 0.5 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
0.2 | 10.7 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.2 | 1.2 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.2 | 0.5 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
0.2 | 1.2 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
0.2 | 0.5 | GO:0004637 | phosphoribosylamine-glycine ligase activity(GO:0004637) |
0.2 | 1.7 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
0.2 | 2.5 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
0.2 | 0.8 | GO:0004359 | glutaminase activity(GO:0004359) |
0.2 | 2.1 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.2 | 0.8 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
0.2 | 39.5 | GO:0003924 | GTPase activity(GO:0003924) |
0.2 | 4.7 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.2 | 7.5 | GO:0015485 | cholesterol binding(GO:0015485) |
0.2 | 13.7 | GO:0008201 | heparin binding(GO:0008201) |
0.2 | 1.4 | GO:0010181 | FMN binding(GO:0010181) |
0.2 | 1.4 | GO:0030332 | cyclin binding(GO:0030332) |
0.1 | 0.7 | GO:1990188 | euchromatin binding(GO:1990188) |
0.1 | 1.5 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
0.1 | 0.6 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
0.1 | 4.4 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.1 | 1.7 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.1 | 1.3 | GO:0070411 | I-SMAD binding(GO:0070411) |
0.1 | 0.7 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
0.1 | 1.6 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
0.1 | 4.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.1 | 0.4 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
0.1 | 7.5 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.1 | 0.5 | GO:0004126 | cytidine deaminase activity(GO:0004126) pyrroline-5-carboxylate reductase activity(GO:0004735) |
0.1 | 0.4 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
0.1 | 1.5 | GO:0004659 | prenyltransferase activity(GO:0004659) |
0.1 | 0.2 | GO:0016615 | malate dehydrogenase activity(GO:0016615) |
0.1 | 0.2 | GO:0048256 | flap endonuclease activity(GO:0048256) |
0.1 | 0.6 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.1 | 2.2 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.1 | 0.3 | GO:1990450 | linear polyubiquitin binding(GO:1990450) |
0.1 | 1.3 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.1 | 2.2 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.1 | 8.4 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
0.1 | 0.9 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.1 | 1.0 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
0.1 | 0.7 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.1 | 0.7 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.1 | 2.0 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.1 | 0.8 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.1 | 1.9 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
0.1 | 0.5 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
0.1 | 1.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.1 | 1.8 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.1 | 1.0 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
0.1 | 0.3 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
0.1 | 0.2 | GO:0001225 | RNA polymerase II transcription coactivator binding(GO:0001225) |
0.1 | 0.4 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
0.1 | 1.2 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.1 | 2.4 | GO:0032947 | protein complex scaffold(GO:0032947) |
0.1 | 1.0 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.1 | 2.9 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.1 | 0.8 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.1 | 1.0 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.1 | 0.4 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
0.1 | 0.3 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
0.1 | 0.9 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.1 | 1.9 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.1 | 1.9 | GO:0030145 | manganese ion binding(GO:0030145) |
0.1 | 2.8 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.1 | 0.3 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.1 | 0.5 | GO:0017022 | myosin binding(GO:0017022) |
0.1 | 0.2 | GO:0046923 | ER retention sequence binding(GO:0046923) |
0.1 | 0.4 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
0.1 | 1.3 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 1.1 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
0.1 | 3.0 | GO:0044325 | ion channel binding(GO:0044325) |
0.1 | 5.1 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) |
0.0 | 0.7 | GO:0000049 | tRNA binding(GO:0000049) |
0.0 | 0.3 | GO:0016428 | tRNA (cytosine) methyltransferase activity(GO:0016427) tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
0.0 | 0.5 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.0 | 0.4 | GO:1990446 | U1 snRNP binding(GO:1990446) |
0.0 | 0.4 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.0 | 0.2 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.0 | 0.1 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
0.0 | 0.4 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.0 | 0.2 | GO:0003998 | acylphosphatase activity(GO:0003998) |
0.0 | 0.4 | GO:0015266 | protein channel activity(GO:0015266) |
0.0 | 0.6 | GO:0005504 | fatty acid binding(GO:0005504) |
0.0 | 0.7 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
0.0 | 0.9 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 0.5 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
0.0 | 0.3 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
0.0 | 0.4 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.0 | 0.3 | GO:0031402 | sodium ion binding(GO:0031402) |
0.0 | 1.4 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.0 | 0.1 | GO:0042284 | sphingolipid delta-4 desaturase activity(GO:0042284) |
0.0 | 0.6 | GO:0030331 | estrogen receptor binding(GO:0030331) |
0.0 | 0.1 | GO:0019779 | Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779) |
0.0 | 0.5 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.0 | 0.2 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
0.0 | 0.1 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
0.0 | 0.7 | GO:0004180 | carboxypeptidase activity(GO:0004180) |
0.0 | 0.1 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.0 | 0.4 | GO:0070628 | proteasome binding(GO:0070628) |
0.0 | 0.1 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
0.0 | 0.1 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.0 | 0.5 | GO:0051183 | vitamin transporter activity(GO:0051183) |
0.0 | 0.8 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 3.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 1.2 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
0.0 | 0.3 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
0.0 | 0.2 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.0 | 0.3 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
0.0 | 0.9 | GO:0008013 | beta-catenin binding(GO:0008013) |
0.0 | 0.1 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 1.9 | GO:0016746 | transferase activity, transferring acyl groups(GO:0016746) |
0.0 | 0.1 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
0.0 | 0.1 | GO:0015265 | urea channel activity(GO:0015265) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 25.6 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
1.4 | 54.1 | PID_ALK1_PATHWAY | ALK1 signaling events |
1.4 | 56.8 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
1.2 | 41.3 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
1.0 | 14.9 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.9 | 65.1 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.9 | 3.6 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
0.8 | 1.7 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
0.8 | 26.6 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.8 | 17.6 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.8 | 10.7 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.7 | 29.6 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.7 | 77.7 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
0.7 | 22.3 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.7 | 18.5 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.7 | 29.5 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.6 | 21.5 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.6 | 25.6 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.6 | 21.4 | PID_INSULIN_PATHWAY | Insulin Pathway |
0.6 | 32.5 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
0.5 | 15.1 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.5 | 14.0 | PID_VEGFR1_2_PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
0.5 | 9.5 | PID_PI3KCI_PATHWAY | Class I PI3K signaling events |
0.5 | 9.3 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
0.5 | 6.4 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
0.4 | 9.2 | PID_ARF_3PATHWAY | Arf1 pathway |
0.4 | 2.5 | PID_ENDOTHELIN_PATHWAY | Endothelins |
0.3 | 5.2 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
0.3 | 3.1 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.3 | 3.0 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.3 | 11.0 | PID_ATM_PATHWAY | ATM pathway |
0.3 | 3.9 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
0.3 | 2.5 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
0.3 | 8.8 | PID_ATR_PATHWAY | ATR signaling pathway |
0.3 | 2.0 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.3 | 0.5 | PID_GMCSF_PATHWAY | GMCSF-mediated signaling events |
0.3 | 11.4 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.3 | 13.2 | PID_AP1_PATHWAY | AP-1 transcription factor network |
0.3 | 3.6 | PID_IFNG_PATHWAY | IFN-gamma pathway |
0.2 | 16.7 | PID_P73PATHWAY | p73 transcription factor network |
0.2 | 2.5 | PID_IL27_PATHWAY | IL27-mediated signaling events |
0.2 | 9.2 | PID_BMP_PATHWAY | BMP receptor signaling |
0.2 | 2.7 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
0.2 | 1.3 | PID_IL1_PATHWAY | IL1-mediated signaling events |
0.2 | 3.6 | ST_GA13_PATHWAY | G alpha 13 Pathway |
0.2 | 3.5 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.2 | 4.1 | PID_RHOA_PATHWAY | RhoA signaling pathway |
0.2 | 2.7 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.1 | 2.3 | PID_BCR_5PATHWAY | BCR signaling pathway |
0.1 | 1.1 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
0.1 | 0.8 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
0.1 | 2.1 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
0.1 | 17.7 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.1 | 7.8 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
0.1 | 3.0 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.1 | 2.5 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
0.1 | 1.9 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
0.1 | 1.8 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.1 | 0.6 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.1 | 1.7 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
0.1 | 4.6 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
0.1 | 0.6 | PID_MYC_PATHWAY | C-MYC pathway |
0.1 | 1.0 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.1 | 3.2 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
0.1 | 0.4 | PID_FOXO_PATHWAY | FoxO family signaling |
0.1 | 6.0 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 1.6 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
0.0 | 0.4 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
0.0 | 1.7 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
0.0 | 0.4 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
0.0 | 0.5 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.6 | 26.3 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
2.2 | 4.4 | REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL | Genes involved in Cell surface interactions at the vascular wall |
1.9 | 34.1 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
1.9 | 30.2 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
1.8 | 58.0 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
1.8 | 68.6 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
1.8 | 23.3 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
1.7 | 27.9 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
1.7 | 46.9 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
1.7 | 38.7 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
1.5 | 39.8 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
1.5 | 19.4 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
1.4 | 45.7 | REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
1.4 | 33.9 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
1.4 | 18.4 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
1.4 | 22.6 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
1.4 | 9.7 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
1.3 | 7.9 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
1.3 | 16.9 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
1.3 | 20.8 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
1.3 | 11.3 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PS | Genes involved in Acyl chain remodelling of PS |
1.2 | 39.2 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
1.1 | 11.3 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
1.1 | 21.9 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
1.1 | 22.6 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
1.1 | 16.0 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
1.0 | 10.4 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
1.0 | 24.5 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
1.0 | 22.7 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
1.0 | 9.9 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.9 | 2.8 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
0.9 | 17.0 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
0.8 | 7.1 | REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
0.8 | 13.2 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
0.8 | 18.4 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.8 | 18.4 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.7 | 16.4 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
0.7 | 28.3 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.7 | 8.0 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.7 | 2.9 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
0.7 | 8.5 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.7 | 6.9 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.7 | 5.3 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
0.6 | 1.9 | REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
0.6 | 2.6 | REACTOME_DSCAM_INTERACTIONS | Genes involved in DSCAM interactions |
0.6 | 3.8 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
0.6 | 4.3 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
0.6 | 16.7 | REACTOME_IL_3_5_AND_GM_CSF_SIGNALING | Genes involved in Interleukin-3, 5 and GM-CSF signaling |
0.6 | 6.1 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.6 | 14.4 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
0.5 | 5.9 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.5 | 5.5 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.5 | 6.0 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.5 | 4.9 | REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
0.5 | 6.3 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.5 | 7.0 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.5 | 5.0 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
0.5 | 3.2 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
0.5 | 3.2 | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
0.4 | 4.9 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.4 | 18.2 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
0.4 | 13.2 | REACTOME_REGULATION_OF_INSULIN_SECRETION | Genes involved in Regulation of Insulin Secretion |
0.4 | 3.6 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.4 | 6.6 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.4 | 5.2 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.4 | 14.4 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.3 | 14.7 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.3 | 1.3 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.3 | 11.3 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.3 | 6.6 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
0.3 | 13.2 | REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
0.3 | 2.3 | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | Genes involved in Signaling by constitutively active EGFR |
0.3 | 5.1 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.3 | 3.4 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.3 | 7.8 | REACTOME_DOUBLE_STRAND_BREAK_REPAIR | Genes involved in Double-Strand Break Repair |
0.3 | 3.1 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
0.3 | 6.9 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
0.2 | 5.2 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
0.2 | 1.0 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
0.2 | 2.1 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.2 | 6.4 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.2 | 2.4 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
0.2 | 13.8 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.2 | 2.3 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
0.2 | 4.8 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.2 | 4.7 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
0.2 | 1.8 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
0.2 | 1.5 | REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR | Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) |
0.2 | 0.7 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
0.2 | 2.1 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
0.2 | 6.0 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.2 | 2.5 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.1 | 1.6 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
0.1 | 0.3 | REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP | Genes involved in Destabilization of mRNA by KSRP |
0.1 | 3.0 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.1 | 1.1 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
0.1 | 3.4 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.1 | 14.5 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
0.1 | 2.0 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.1 | 0.8 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
0.1 | 1.2 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
0.1 | 0.9 | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
0.1 | 0.8 | REACTOME_PERK_REGULATED_GENE_EXPRESSION | Genes involved in PERK regulated gene expression |
0.1 | 0.6 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PC | Genes involved in Acyl chain remodelling of PC |
0.1 | 0.7 | REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING | Genes involved in Integrin alphaIIb beta3 signaling |
0.1 | 1.5 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.1 | 2.2 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.1 | 1.3 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.1 | 0.9 | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | Genes involved in Transmission across Chemical Synapses |
0.1 | 1.3 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
0.1 | 4.2 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.1 | 0.6 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.1 | 4.5 | REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | Genes involved in G alpha (q) signalling events |
0.1 | 1.4 | REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM | Genes involved in Keratan sulfate/keratin metabolism |
0.1 | 1.9 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.1 | 2.3 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.1 | 3.9 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.1 | 0.5 | REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM | Genes involved in Abacavir transport and metabolism |
0.1 | 3.0 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
0.1 | 0.3 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
0.1 | 3.6 | REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
0.1 | 1.5 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.1 | 1.7 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 2.3 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 0.8 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
0.0 | 0.1 | REACTOME_TRIF_MEDIATED_TLR3_SIGNALING | Genes involved in TRIF mediated TLR3 signaling |
0.0 | 1.3 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.0 | 0.1 | REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | Genes involved in Integration of energy metabolism |
0.0 | 1.3 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.0 | 1.1 | REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | Genes involved in G alpha (s) signalling events |
0.0 | 0.4 | REACTOME_SIGNALING_BY_NOTCH4 | Genes involved in Signaling by NOTCH4 |
0.0 | 1.0 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
0.0 | 1.6 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.6 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
0.0 | 2.6 | REACTOME_TRANSLATION | Genes involved in Translation |
0.0 | 0.7 | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
0.0 | 0.1 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
0.0 | 0.2 | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
0.0 | 0.7 | REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE | Genes involved in Late Phase of HIV Life Cycle |
0.0 | 0.1 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |