Motif ID: Tfap2a

Z-value: 1.267


Transcription factors associated with Tfap2a:

Gene SymbolEntrez IDGene Name
Tfap2a ENSMUSG00000021359.9 Tfap2a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfap2amm10_v2_chr13_-_40733768_407338360.056.6e-01Click!


Activity profile for motif Tfap2a.

activity profile for motif Tfap2a


Sorted Z-values histogram for motif Tfap2a

Sorted Z-values for motif Tfap2a



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfap2a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_100015817 16.969 ENSMUST00000130190.1
ENSMUST00000020129.7
Kitl

kit ligand

chr15_-_45114926 14.897 ENSMUST00000022967.5
Kcnv1
potassium channel, subfamily V, member 1
chr12_-_67221221 13.398 ENSMUST00000178814.1
ENSMUST00000179345.2
Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr9_+_21184103 12.049 ENSMUST00000115458.2
Pde4a
phosphodiesterase 4A, cAMP specific
chr1_+_159737510 9.975 ENSMUST00000111669.3
Tnr
tenascin R
chr17_+_69969073 9.544 ENSMUST00000133983.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr10_-_86498836 9.498 ENSMUST00000120638.1
Syn3
synapsin III
chr17_+_69969387 9.156 ENSMUST00000146730.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr9_+_26733728 8.971 ENSMUST00000160899.1
ENSMUST00000161431.1
ENSMUST00000159799.1
B3gat1


beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)


chr13_-_98206151 8.890 ENSMUST00000109426.1
Arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chr5_-_146585239 8.736 ENSMUST00000036211.6
Gpr12
G-protein coupled receptor 12
chr17_+_69969217 8.585 ENSMUST00000060072.5
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr7_+_121392266 8.577 ENSMUST00000084628.3
Hs3st2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chrX_-_162643575 7.971 ENSMUST00000101102.1
Reps2
RALBP1 associated Eps domain containing protein 2
chrX_-_162643629 7.954 ENSMUST00000112334.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr9_+_109931774 7.700 ENSMUST00000169851.2
Map4
microtubule-associated protein 4
chr10_+_86021961 7.271 ENSMUST00000130320.1
Fbxo7
F-box protein 7
chr12_-_76822510 7.259 ENSMUST00000021459.7
Rab15
RAB15, member RAS oncogene family
chr14_+_33923582 7.147 ENSMUST00000168727.1
Gdf10
growth differentiation factor 10
chr14_+_68083853 7.048 ENSMUST00000022639.7
Nefl
neurofilament, light polypeptide
chr9_+_34904913 6.951 ENSMUST00000045091.6
Kirrel3
kin of IRRE like 3 (Drosophila)
chr8_+_70493156 6.712 ENSMUST00000008032.7
Crlf1
cytokine receptor-like factor 1
chr10_-_86498872 6.426 ENSMUST00000121789.1
Syn3
synapsin III
chr2_-_163918683 6.268 ENSMUST00000044734.2
Rims4
regulating synaptic membrane exocytosis 4
chr17_-_29237759 5.765 ENSMUST00000137727.1
ENSMUST00000024805.7
Cpne5

copine V

chr14_-_102982630 5.612 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr4_-_149698698 5.522 ENSMUST00000038859.7
ENSMUST00000105690.2
Pik3cd

phosphatidylinositol 3-kinase catalytic delta polypeptide

chr4_-_149698552 5.344 ENSMUST00000134534.1
ENSMUST00000146612.1
ENSMUST00000105688.3
Pik3cd


phosphatidylinositol 3-kinase catalytic delta polypeptide


chr19_+_59260878 5.280 ENSMUST00000026084.3
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr15_-_37791993 5.198 ENSMUST00000168992.1
ENSMUST00000148652.1
Ncald

neurocalcin delta

chr9_+_47530173 5.108 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
Cadm1





cell adhesion molecule 1





chr3_-_94786469 5.084 ENSMUST00000107273.1
Cgn
cingulin
chr12_+_109544498 5.029 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr11_+_32296489 4.969 ENSMUST00000093207.3
Hba-a2
hemoglobin alpha, adult chain 2
chr9_+_26733845 4.911 ENSMUST00000115269.2
B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr9_-_112187898 4.904 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr6_-_50456085 4.815 ENSMUST00000146341.1
ENSMUST00000071728.4
Osbpl3

oxysterol binding protein-like 3

chr5_-_67847400 4.782 ENSMUST00000113652.1
ENSMUST00000113651.1
ENSMUST00000037380.8
Atp8a1


ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1


chr4_+_57434247 4.676 ENSMUST00000102905.1
Palm2
paralemmin 2
chr17_-_87797994 4.663 ENSMUST00000055221.7
Kcnk12
potassium channel, subfamily K, member 12
chr12_+_40446050 4.539 ENSMUST00000037488.6
Dock4
dedicator of cytokinesis 4
chr1_-_54194048 4.345 ENSMUST00000120904.1
Hecw2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr1_-_38836090 4.324 ENSMUST00000147695.1
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr1_-_193370225 4.305 ENSMUST00000169907.1
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr1_-_193370260 4.237 ENSMUST00000016323.4
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr7_+_6415164 4.235 ENSMUST00000160218.1
Smim17
small integral membrane protein 17
chr3_-_94786430 4.218 ENSMUST00000107272.1
Cgn
cingulin
chr13_+_24845122 4.212 ENSMUST00000006893.8
D130043K22Rik
RIKEN cDNA D130043K22 gene
chr13_-_110280103 4.143 ENSMUST00000167824.1
Rab3c
RAB3C, member RAS oncogene family
chr19_+_10041548 4.139 ENSMUST00000115995.2
Fads3
fatty acid desaturase 3
chr1_+_23762003 4.068 ENSMUST00000140583.1
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr19_+_42255704 4.046 ENSMUST00000087123.5
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr3_+_26331150 3.917 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr3_-_152668135 3.902 ENSMUST00000045262.6
Ak5
adenylate kinase 5
chr2_-_166155624 3.864 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr4_+_42714926 3.833 ENSMUST00000178454.1
Gm21955
predicted gene, 21955
chr13_-_99516537 3.747 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr18_+_60925612 3.680 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr11_+_62575981 3.653 ENSMUST00000102643.1
Trpv2
transient receptor potential cation channel, subfamily V, member 2
chr9_+_21165714 3.645 ENSMUST00000039413.8
Pde4a
phosphodiesterase 4A, cAMP specific
chrX_-_48208566 3.578 ENSMUST00000037960.4
Zdhhc9
zinc finger, DHHC domain containing 9
chr2_-_166155272 3.541 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr2_-_32312162 3.540 ENSMUST00000155269.1
Dnm1
dynamin 1
chr19_+_53600377 3.527 ENSMUST00000025930.9
Smc3
structural maintenance of chromosomes 3
chr4_+_85205120 3.488 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr11_-_66525964 3.417 ENSMUST00000066679.6
Shisa6
shisa homolog 6 (Xenopus laevis)
chr15_-_64060439 3.400 ENSMUST00000063838.4
Fam49b
family with sequence similarity 49, member B
chr1_-_190979280 3.378 ENSMUST00000166139.1
Vash2
vasohibin 2
chr18_+_37955126 3.365 ENSMUST00000176902.1
ENSMUST00000176104.1
Rell2

RELT-like 2

chr2_+_118779703 3.360 ENSMUST00000063975.3
ENSMUST00000037547.2
ENSMUST00000110846.1
ENSMUST00000110843.1
Disp2



dispatched homolog 2 (Drosophila)



chr12_-_40038025 3.321 ENSMUST00000101472.3
Arl4a
ADP-ribosylation factor-like 4A
chr3_-_84480419 3.283 ENSMUST00000107689.1
Fhdc1
FH2 domain containing 1
chr11_-_103954015 3.253 ENSMUST00000103075.4
Nsf
N-ethylmaleimide sensitive fusion protein
chr3_-_30969399 3.233 ENSMUST00000177992.1
ENSMUST00000129817.2
ENSMUST00000168645.1
ENSMUST00000108255.1
ENSMUST00000064718.5
ENSMUST00000099163.3
Phc3





polyhomeotic-like 3 (Drosophila)





chr5_+_72914554 3.215 ENSMUST00000143829.1
Slain2
SLAIN motif family, member 2
chr13_+_54949388 3.195 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr11_-_89302545 3.165 ENSMUST00000061728.3
Nog
noggin
chr14_+_70553687 3.160 ENSMUST00000161069.1
Hr
hairless
chr14_-_66280949 3.150 ENSMUST00000111121.1
ENSMUST00000022622.7
ENSMUST00000089250.2
Ptk2b


PTK2 protein tyrosine kinase 2 beta


chr5_-_121502980 3.137 ENSMUST00000079368.3
Adam1b
a disintegrin and metallopeptidase domain 1b
chr1_-_23383149 3.137 ENSMUST00000027343.5
Ogfrl1
opioid growth factor receptor-like 1
chr7_-_65156416 3.090 ENSMUST00000148459.1
ENSMUST00000119118.1
Fam189a1

family with sequence similarity 189, member A1

chr18_-_38209762 3.087 ENSMUST00000057185.6
Pcdh1
protocadherin 1
chr18_+_62548911 3.083 ENSMUST00000055725.4
ENSMUST00000162365.1
Spink10

serine peptidase inhibitor, Kazal type 10

chr8_+_40423786 3.081 ENSMUST00000049389.4
ENSMUST00000128166.1
ENSMUST00000167766.1
Zdhhc2


zinc finger, DHHC domain containing 2


chr4_+_43401232 3.078 ENSMUST00000125399.1
Rusc2
RUN and SH3 domain containing 2
chr7_-_98178254 3.077 ENSMUST00000040971.7
Capn5
calpain 5
chr7_-_119184374 3.068 ENSMUST00000084650.4
Gpr139
G protein-coupled receptor 139
chr12_-_109068173 3.059 ENSMUST00000073156.7
Begain
brain-enriched guanylate kinase-associated
chr14_-_29721835 3.005 ENSMUST00000022567.7
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr1_+_23761749 2.952 ENSMUST00000144602.1
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr1_+_132880273 2.893 ENSMUST00000027706.3
Lrrn2
leucine rich repeat protein 2, neuronal
chr2_+_109890846 2.881 ENSMUST00000028583.7
Lin7c
lin-7 homolog C (C. elegans)
chr5_-_24030649 2.868 ENSMUST00000030849.6
Fam126a
family with sequence similarity 126, member A
chr18_+_34220978 2.823 ENSMUST00000079362.5
ENSMUST00000115781.3
Apc

adenomatosis polyposis coli

chr16_+_93832121 2.744 ENSMUST00000044068.6
Morc3
microrchidia 3
chr6_-_124769548 2.676 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
Eno2


enolase 2, gamma neuronal


chr12_-_40445754 2.668 ENSMUST00000069692.8
ENSMUST00000069637.7
Zfp277

zinc finger protein 277

chr14_+_56668242 2.641 ENSMUST00000116468.1
Mphosph8
M-phase phosphoprotein 8
chr18_-_16809233 2.633 ENSMUST00000025166.7
Cdh2
cadherin 2
chr8_+_41239718 2.626 ENSMUST00000045218.7
Pcm1
pericentriolar material 1
chr11_-_121388186 2.587 ENSMUST00000106107.2
Rab40b
Rab40b, member RAS oncogene family
chr19_-_53944621 2.538 ENSMUST00000135402.2
Bbip1
BBSome interacting protein 1
chr10_-_5922385 2.525 ENSMUST00000131996.1
ENSMUST00000064225.7
Rgs17

regulator of G-protein signaling 17

chr4_+_43383449 2.474 ENSMUST00000135216.1
ENSMUST00000152322.1
Rusc2

RUN and SH3 domain containing 2

chr6_+_17306335 2.439 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1



caveolin 1, caveolae protein



chr19_-_28911879 2.409 ENSMUST00000179171.1
AC163993.1
AC163993.1
chr13_-_101768154 2.367 ENSMUST00000055518.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chrX_-_107403295 2.354 ENSMUST00000033591.5
Itm2a
integral membrane protein 2A
chr3_+_33799791 2.352 ENSMUST00000099153.3
Ttc14
tetratricopeptide repeat domain 14
chr7_+_128611328 2.346 ENSMUST00000098007.4
ENSMUST00000043138.6
Inpp5f

inositol polyphosphate-5-phosphatase F

chr16_+_20589471 2.342 ENSMUST00000100074.3
ENSMUST00000096197.4
Vwa5b2

von Willebrand factor A domain containing 5B2

chr11_+_117654211 2.320 ENSMUST00000026658.6
Tnrc6c
trinucleotide repeat containing 6C
chr6_+_143285988 2.317 ENSMUST00000160951.1
D6Ertd474e
DNA segment, Chr 6, ERATO Doi 474, expressed
chr18_-_12305638 2.309 ENSMUST00000122408.1
ENSMUST00000118525.1
ENSMUST00000142066.1
Ankrd29


ankyrin repeat domain 29


chr8_-_126971062 2.269 ENSMUST00000045994.6
Rbm34
RNA binding motif protein 34
chr19_+_5568002 2.263 ENSMUST00000096318.3
Ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr11_-_103101609 2.248 ENSMUST00000103077.1
Plcd3
phospholipase C, delta 3
chr13_+_109632760 2.243 ENSMUST00000135275.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr9_+_89909775 2.240 ENSMUST00000034912.4
ENSMUST00000034909.4
Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr7_-_98656530 2.239 ENSMUST00000038359.4
2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr9_-_97111117 2.237 ENSMUST00000085206.4
Slc25a36
solute carrier family 25, member 36
chr11_+_75348433 2.230 ENSMUST00000044530.2
Smyd4
SET and MYND domain containing 4
chr11_+_93099284 2.216 ENSMUST00000092780.3
ENSMUST00000107863.2
Car10

carbonic anhydrase 10

chr17_+_46681038 2.200 ENSMUST00000002845.6
Mea1
male enhanced antigen 1
chr13_+_30659999 2.189 ENSMUST00000091672.6
ENSMUST00000110310.1
ENSMUST00000095914.5
Dusp22


dual specificity phosphatase 22


chr16_+_32608920 2.187 ENSMUST00000023486.8
Tfrc
transferrin receptor
chr15_-_38519227 2.175 ENSMUST00000110328.1
ENSMUST00000110329.1
ENSMUST00000065308.5
Azin1


antizyme inhibitor 1


chr19_+_55253369 2.153 ENSMUST00000043150.4
Acsl5
acyl-CoA synthetase long-chain family member 5
chr2_-_73386396 2.151 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
Gpr155


G protein-coupled receptor 155


chr10_+_81575306 2.135 ENSMUST00000146916.1
Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr2_+_121358591 2.123 ENSMUST00000000317.6
ENSMUST00000129130.1
Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chr1_+_96872221 2.103 ENSMUST00000181489.1
Gm5101
predicted gene 5101
chr1_-_190978954 2.094 ENSMUST00000047409.6
Vash2
vasohibin 2
chr13_+_96542727 2.084 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr5_-_24030297 2.082 ENSMUST00000101513.2
Fam126a
family with sequence similarity 126, member A
chr6_-_37299950 2.062 ENSMUST00000101532.3
Dgki
diacylglycerol kinase, iota
chr1_+_191717834 2.049 ENSMUST00000110855.1
ENSMUST00000133076.1
Lpgat1

lysophosphatidylglycerol acyltransferase 1

chr4_+_136310991 2.028 ENSMUST00000084219.5
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr16_-_34573526 2.026 ENSMUST00000114961.1
Kalrn
kalirin, RhoGEF kinase
chr11_-_115297510 2.012 ENSMUST00000056153.7
Fads6
fatty acid desaturase domain family, member 6
chr16_+_32608973 2.004 ENSMUST00000120680.1
Tfrc
transferrin receptor
chr3_+_65528404 1.998 ENSMUST00000047906.3
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
chr13_+_41249841 1.993 ENSMUST00000165561.2
Smim13
small integral membrane protein 13
chr10_-_85185003 1.983 ENSMUST00000020227.9
Cry1
cryptochrome 1 (photolyase-like)
chr19_-_45816007 1.976 ENSMUST00000079431.3
ENSMUST00000026247.6
ENSMUST00000162528.2
Kcnip2


Kv channel-interacting protein 2


chr10_+_79716588 1.959 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr2_+_29124972 1.958 ENSMUST00000061578.2
Setx
senataxin
chr12_+_24651346 1.956 ENSMUST00000020982.5
Klf11
Kruppel-like factor 11
chr5_+_107437908 1.950 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr18_-_46728342 1.933 ENSMUST00000035804.7
Cdo1
cysteine dioxygenase 1, cytosolic
chr17_+_24470393 1.929 ENSMUST00000053024.6
Pgp
phosphoglycolate phosphatase
chr7_+_97081711 1.921 ENSMUST00000004622.5
Gab2
growth factor receptor bound protein 2-associated protein 2
chr8_+_13405080 1.921 ENSMUST00000033827.7
Grk1
G protein-coupled receptor kinase 1
chr8_+_107293500 1.920 ENSMUST00000151114.1
ENSMUST00000075922.4
ENSMUST00000125721.1
Nfat5


nuclear factor of activated T cells 5


chr16_+_24448082 1.904 ENSMUST00000078988.2
Lpp
LIM domain containing preferred translocation partner in lipoma
chr4_+_43381979 1.882 ENSMUST00000035645.5
ENSMUST00000144911.1
Rusc2

RUN and SH3 domain containing 2

chr6_-_129533267 1.865 ENSMUST00000181594.1
1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr11_-_95699143 1.859 ENSMUST00000062249.2
Gm9796
predicted gene 9796
chr1_-_52490736 1.855 ENSMUST00000170269.1
Nab1
Ngfi-A binding protein 1
chr11_+_118428203 1.853 ENSMUST00000124861.1
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr13_-_34345174 1.846 ENSMUST00000040336.5
Slc22a23
solute carrier family 22, member 23
chr5_-_124249758 1.844 ENSMUST00000162812.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr11_+_46055973 1.843 ENSMUST00000011400.7
Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chrX_+_93675088 1.839 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr11_+_32283511 1.827 ENSMUST00000093209.3
Hba-a1
hemoglobin alpha, adult chain 1
chr11_+_103101682 1.818 ENSMUST00000107040.3
ENSMUST00000140372.1
ENSMUST00000024492.8
ENSMUST00000134884.1
Acbd4



acyl-Coenzyme A binding domain containing 4



chr15_+_79108911 1.814 ENSMUST00000040320.8
Micall1
microtubule associated monooxygenase, calponin and LIM domain containing -like 1
chr17_+_87282880 1.797 ENSMUST00000041110.5
ENSMUST00000125875.1
Ttc7

tetratricopeptide repeat domain 7

chr9_+_25252439 1.795 ENSMUST00000115272.2
ENSMUST00000165594.2
Sept7

septin 7

chr15_-_89128634 1.794 ENSMUST00000082197.5
Hdac10
histone deacetylase 10
chr11_+_121204420 1.785 ENSMUST00000038831.8
ENSMUST00000106117.1
Hexdc

hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing

chr12_+_18853872 1.782 ENSMUST00000101582.3
Gm3944
predicted gene 3944
chr3_-_107969162 1.778 ENSMUST00000004136.8
ENSMUST00000106678.1
Gstm3

glutathione S-transferase, mu 3

chr2_+_69861638 1.772 ENSMUST00000112260.1
Ssb
Sjogren syndrome antigen B
chr1_+_23761926 1.759 ENSMUST00000063663.5
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr5_-_113310729 1.747 ENSMUST00000112325.1
ENSMUST00000048112.6
Sgsm1

small G protein signaling modulator 1

chr10_-_80844025 1.734 ENSMUST00000053986.7
Lingo3
leucine rich repeat and Ig domain containing 3
chr5_+_108065742 1.734 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
Mtf2


metal response element binding transcription factor 2


chr7_-_128461168 1.724 ENSMUST00000106228.1
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr2_-_102400863 1.714 ENSMUST00000102573.1
Trim44
tripartite motif-containing 44
chr4_+_47353283 1.706 ENSMUST00000044234.7
Tgfbr1
transforming growth factor, beta receptor I
chr11_+_75468040 1.703 ENSMUST00000043598.7
ENSMUST00000108435.1
Tlcd2

TLC domain containing 2

chr15_+_74516196 1.703 ENSMUST00000042035.9
Bai1
brain-specific angiogenesis inhibitor 1
chr12_-_31634592 1.690 ENSMUST00000020979.7
ENSMUST00000177962.1
Bcap29

B cell receptor associated protein 29

chr6_+_36388055 1.680 ENSMUST00000172278.1
Chrm2
cholinergic receptor, muscarinic 2, cardiac
chr17_+_83706137 1.674 ENSMUST00000112350.1
ENSMUST00000112349.2
ENSMUST00000112352.3
Mta3


metastasis associated 3


chr5_+_105876532 1.668 ENSMUST00000150440.1
ENSMUST00000031227.4
Zfp326

zinc finger protein 326

chr7_+_100227638 1.664 ENSMUST00000054436.8
Pgm2l1
phosphoglucomutase 2-like 1
chr7_-_3677509 1.655 ENSMUST00000038743.8
Tmc4
transmembrane channel-like gene family 4
chr14_-_65953728 1.655 ENSMUST00000042046.3
Scara3
scavenger receptor class A, member 3
chr4_+_125085134 1.653 ENSMUST00000154689.1
ENSMUST00000055213.4
ENSMUST00000106171.2
Meaf6


MYST/Esa1-associated factor 6


chr4_+_129335593 1.635 ENSMUST00000141235.1
Zbtb8os
zinc finger and BTB domain containing 8 opposite strand
chr9_+_82829806 1.633 ENSMUST00000113245.2
ENSMUST00000034783.4
Irak1bp1

interleukin-1 receptor-associated kinase 1 binding protein 1

chr4_+_148558422 1.619 ENSMUST00000017408.7
ENSMUST00000076022.6
Exosc10

exosome component 10

chrX_-_59134421 1.614 ENSMUST00000033473.5
Fgf13
fibroblast growth factor 13
chr5_-_113310697 1.612 ENSMUST00000154248.1
Sgsm1
small G protein signaling modulator 1
chr2_+_69861562 1.611 ENSMUST00000090852.4
ENSMUST00000166411.1
Ssb

Sjogren syndrome antigen B

chr2_+_145934800 1.604 ENSMUST00000138774.1
ENSMUST00000152515.1
ENSMUST00000130168.1
ENSMUST00000133433.1
ENSMUST00000118002.1
4930529M08Rik




RIKEN cDNA 4930529M08 gene




chr10_+_81575257 1.598 ENSMUST00000135211.1
Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 17.0 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
2.5 10.0 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
2.3 7.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
2.1 27.3 GO:0070842 aggresome assembly(GO:0070842)
1.9 7.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.7 5.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
1.6 10.9 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
1.5 7.7 GO:0051012 microtubule sliding(GO:0051012)
1.4 7.0 GO:0002121 inter-male aggressive behavior(GO:0002121)
1.2 4.8 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
1.2 3.5 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
1.1 4.5 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
1.1 22.7 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.1 6.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
1.1 3.2 GO:1905223 epicardium morphogenesis(GO:1905223)
1.0 3.1 GO:0010752 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752)
1.0 3.0 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.9 7.3 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.9 5.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.8 3.4 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.8 2.5 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.8 3.2 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.8 3.9 GO:0033762 response to glucagon(GO:0033762)
0.7 8.9 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.7 2.2 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.7 2.8 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.7 7.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.7 2.1 GO:0046959 habituation(GO:0046959)
0.7 3.4 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.7 2.0 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.6 1.9 GO:0019401 alditol biosynthetic process(GO:0019401)
0.6 2.6 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.6 1.2 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.6 2.3 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.6 2.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.6 2.8 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.5 17.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.5 1.6 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.5 1.6 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.5 2.6 GO:0021764 amygdala development(GO:0021764)
0.5 2.5 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.5 3.5 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.5 3.5 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.5 1.5 GO:0019858 cytosine metabolic process(GO:0019858)
0.5 1.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.5 5.7 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.5 4.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 3.5 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.4 3.1 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.4 2.6 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.4 1.7 GO:0061047 positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.4 1.2 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.4 1.2 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.4 3.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 2.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.4 2.4 GO:0002317 plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.4 3.0 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.4 2.2 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.4 6.8 GO:0045830 positive regulation of isotype switching(GO:0045830)
0.4 1.4 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.4 1.1 GO:0090649 cellular response to manganese ion(GO:0071287) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.3 3.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 1.4 GO:0061623 glycolytic process from galactose(GO:0061623)
0.3 1.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.3 1.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 1.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.3 2.6 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.3 1.6 GO:0060178 regulation of exocyst localization(GO:0060178)
0.3 0.9 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.3 2.4 GO:0010459 negative regulation of heart rate(GO:0010459)
0.3 0.9 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.3 0.9 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.3 1.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.3 1.4 GO:0072675 osteoclast fusion(GO:0072675)
0.3 0.8 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.3 2.2 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.3 1.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 1.6 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.3 1.1 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.3 3.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.3 6.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 0.5 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
0.3 0.8 GO:2000468 regulation of peroxidase activity(GO:2000468)
0.3 7.7 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.3 5.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.3 0.8 GO:0032493 response to bacterial lipoprotein(GO:0032493)
0.3 1.0 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.2 0.5 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.2 7.0 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.2 3.6 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 2.6 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.2 1.8 GO:0080184 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.2 1.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 1.8 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.2 7.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 0.9 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.2 3.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 1.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.2 4.0 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 1.2 GO:0016266 O-glycan processing(GO:0016266)
0.2 9.3 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.2 0.8 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.2 1.2 GO:0006108 malate metabolic process(GO:0006108)
0.2 0.8 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.2 4.6 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 0.9 GO:0008355 olfactory learning(GO:0008355)
0.2 3.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 1.6 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2 0.7 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.2 3.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 1.1 GO:0006020 inositol metabolic process(GO:0006020)
0.2 1.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.2 1.9 GO:0033005 positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.2 3.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.2 1.4 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2 3.1 GO:0018345 protein palmitoylation(GO:0018345)
0.2 6.0 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.2 1.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 1.8 GO:0031268 pseudopodium organization(GO:0031268)
0.2 2.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 1.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.2 0.6 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 2.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.2 3.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.2 3.3 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.2 1.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.2 0.9 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.2 0.9 GO:0046514 ceramide catabolic process(GO:0046514)
0.1 1.0 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 2.5 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 0.9 GO:0032796 uropod organization(GO:0032796)
0.1 12.1 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.1 2.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 2.3 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.1 2.0 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.6 GO:1905247 modulation of age-related behavioral decline(GO:0090647) positive regulation of beta-amyloid clearance(GO:1900223) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) negative regulation of metalloendopeptidase activity(GO:1904684) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 0.9 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.9 GO:0008228 opsonization(GO:0008228)
0.1 0.8 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 2.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.9 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.6 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 2.7 GO:2000772 regulation of cellular senescence(GO:2000772)
0.1 2.0 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 1.0 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 4.9 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.4 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.1 1.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 4.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.3 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 2.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 2.6 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 0.4 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 1.3 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.2 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.3 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710)
0.1 0.6 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 5.9 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.1 4.3 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.1 1.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 2.0 GO:0008209 androgen metabolic process(GO:0008209)
0.1 3.1 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.1 1.4 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 1.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.1 0.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.1 GO:0031100 organ regeneration(GO:0031100)
0.1 0.9 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.2 GO:0035087 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.1 0.6 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 1.7 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 0.4 GO:0034214 protein hexamerization(GO:0034214)
0.1 2.0 GO:0061157 positive regulation of mRNA catabolic process(GO:0061014) mRNA destabilization(GO:0061157)
0.1 0.4 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 1.2 GO:0002021 response to dietary excess(GO:0002021)
0.1 0.2 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300) negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375) negative regulation of intestinal absorption(GO:1904479)
0.1 9.3 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 3.1 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.1 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 1.0 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 3.0 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 0.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 1.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 1.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.8 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 2.2 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 3.6 GO:0017157 regulation of exocytosis(GO:0017157)
0.1 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.2 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.6 GO:0032060 bleb assembly(GO:0032060)
0.1 4.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 1.1 GO:0006308 DNA catabolic process(GO:0006308)
0.1 0.5 GO:0002643 regulation of tolerance induction(GO:0002643)
0.1 7.6 GO:0007623 circadian rhythm(GO:0007623)
0.1 0.2 GO:0015867 ATP transport(GO:0015867)
0.1 1.1 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 1.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.2 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.0 0.5 GO:0050890 cognition(GO:0050890)
0.0 1.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 1.4 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 3.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 1.7 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 1.4 GO:0001541 ovarian follicle development(GO:0001541)
0.0 7.0 GO:0006874 cellular calcium ion homeostasis(GO:0006874)
0.0 3.0 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.0 1.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 1.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 1.1 GO:0035456 response to interferon-beta(GO:0035456)
0.0 2.7 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 1.0 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.2 GO:0003341 cilium movement(GO:0003341)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 1.1 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.2 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.3 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0 0.0 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.9 GO:0017145 stem cell division(GO:0017145)
0.0 0.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.4 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.7 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.5 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 1.3 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 1.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.5 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.6 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.7 GO:0007041 lysosomal transport(GO:0007041)
0.0 0.7 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.5 GO:0043087 regulation of GTPase activity(GO:0043087)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 10.0 GO:0072534 perineuronal net(GO:0072534)
2.3 7.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
2.2 6.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.7 6.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.5 7.3 GO:1990037 Lewy body core(GO:1990037)
1.2 3.7 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.9 3.5 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.8 12.4 GO:0043196 varicosity(GO:0043196)
0.7 0.7 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.7 2.0 GO:0098855 HCN channel complex(GO:0098855)
0.6 7.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.6 1.8 GO:0005940 septin ring(GO:0005940)
0.5 12.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.4 1.3 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.4 4.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.4 2.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.4 5.5 GO:0016342 catenin complex(GO:0016342)
0.4 6.6 GO:0031045 dense core granule(GO:0031045)
0.3 3.7 GO:0032584 growth cone membrane(GO:0032584)
0.3 1.3 GO:0005745 m-AAA complex(GO:0005745)
0.3 2.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 1.1 GO:0071437 invadopodium(GO:0071437)
0.3 1.7 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 4.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 1.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 3.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 2.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.2 2.5 GO:0034464 BBSome(GO:0034464)
0.2 3.9 GO:0035102 PRC1 complex(GO:0035102)
0.2 5.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 0.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 1.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 8.1 GO:0048786 presynaptic active zone(GO:0048786)
0.2 19.8 GO:0030175 filopodium(GO:0030175)
0.2 0.9 GO:1990745 EARP complex(GO:1990745)
0.2 1.9 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 1.6 GO:0071141 SMAD protein complex(GO:0071141)
0.2 0.5 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 11.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 14.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 4.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 8.3 GO:0016459 myosin complex(GO:0016459)
0.2 5.4 GO:0032420 stereocilium(GO:0032420)
0.2 3.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.9 GO:0061689 tricellular tight junction(GO:0061689)
0.1 2.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 2.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 1.2 GO:0036157 outer dynein arm(GO:0036157)
0.1 2.9 GO:0034451 centriolar satellite(GO:0034451)
0.1 2.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.5 GO:0030057 desmosome(GO:0030057)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.1 1.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 37.1 GO:0014069 postsynaptic density(GO:0014069)
0.1 0.6 GO:0070876 SOSS complex(GO:0070876)
0.1 1.2 GO:0031931 TORC1 complex(GO:0031931)
0.1 3.2 GO:0035371 microtubule plus-end(GO:0035371)
0.1 13.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 2.2 GO:0005581 collagen trimer(GO:0005581)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.5 GO:0034448 EGO complex(GO:0034448)
0.1 1.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.8 GO:0070578 RISC-loading complex(GO:0070578)
0.1 1.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 2.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 7.5 GO:0008021 synaptic vesicle(GO:0008021)
0.1 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 1.3 GO:0000124 SAGA complex(GO:0000124)
0.1 2.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.1 1.4 GO:0002102 podosome(GO:0002102)
0.1 2.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.7 GO:0032300 mismatch repair complex(GO:0032300)
0.1 1.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 7.1 GO:0016605 PML body(GO:0016605)
0.1 0.6 GO:0061574 ASAP complex(GO:0061574)
0.1 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.9 GO:0034706 sodium channel complex(GO:0034706)
0.1 2.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 1.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 15.8 GO:0000139 Golgi membrane(GO:0000139)
0.1 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.9 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 2.9 GO:0005901 caveola(GO:0005901)
0.0 5.5 GO:0030426 growth cone(GO:0030426)
0.0 0.4 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.6 GO:0043218 compact myelin(GO:0043218)
0.0 1.9 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 3.6 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.0 0.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 11.3 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.3 GO:0055037 recycling endosome(GO:0055037)
0.0 3.0 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.4 GO:0009986 cell surface(GO:0009986)
0.0 1.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 26.0 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.9 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.3 GO:0005938 cell cortex(GO:0005938)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 2.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0031083 BLOC-1 complex(GO:0031083)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 22.7 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
2.8 17.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
1.8 5.3 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
1.7 6.8 GO:0031720 haptoglobin binding(GO:0031720)
1.5 7.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.4 4.2 GO:0004998 transferrin receptor activity(GO:0004998)
1.4 10.9 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
1.0 6.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.9 1.8 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.9 3.5 GO:0036033 mediator complex binding(GO:0036033)
0.8 13.5 GO:0046625 sphingolipid binding(GO:0046625)
0.7 2.8 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.7 10.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.7 2.0 GO:0009881 photoreceptor activity(GO:0009881)
0.7 2.0 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.6 2.4 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.5 1.6 GO:0035500 MH2 domain binding(GO:0035500)
0.5 3.2 GO:0005042 netrin receptor activity(GO:0005042)
0.5 2.1 GO:0004111 creatine kinase activity(GO:0004111)
0.5 2.5 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.5 1.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.5 2.5 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.5 2.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.5 1.9 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.5 1.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.5 2.9 GO:0097016 L27 domain binding(GO:0097016)
0.5 2.3 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.5 3.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.5 2.7 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.5 8.6 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.4 1.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.4 2.2 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.4 14.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.4 1.2 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.4 1.2 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.4 1.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.4 1.2 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.4 2.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.4 3.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4 10.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.4 1.8 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.4 3.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.4 1.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.4 3.9 GO:0019206 nucleoside kinase activity(GO:0019206)
0.3 1.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 6.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 7.8 GO:0043274 phospholipase binding(GO:0043274)
0.3 12.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 3.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 0.9 GO:0071633 dihydroceramidase activity(GO:0071633)
0.3 1.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.3 2.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 2.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 1.5 GO:0045545 syndecan binding(GO:0045545)
0.3 2.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 0.8 GO:0004348 glucosylceramidase activity(GO:0004348)
0.2 1.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.2 1.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 2.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.2 1.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.2 0.7 GO:0032137 guanine/thymine mispair binding(GO:0032137) single guanine insertion binding(GO:0032142)
0.2 3.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 1.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 1.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 4.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 7.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 3.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.2 1.9 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 11.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 0.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.2 4.1 GO:0031489 myosin V binding(GO:0031489)
0.2 0.7 GO:0050544 arachidonic acid binding(GO:0050544)
0.2 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 5.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 1.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 0.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 3.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.2 2.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 3.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 0.9 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 0.9 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.2 0.9 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 3.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 1.1 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.1 1.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 1.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 2.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.8 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.6 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 0.4 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.6 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 1.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.9 GO:0046790 virion binding(GO:0046790)
0.1 5.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 2.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 0.8 GO:0015925 galactosidase activity(GO:0015925)
0.1 1.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.3 GO:0030172 troponin C binding(GO:0030172)
0.1 1.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 9.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.3 GO:0017166 vinculin binding(GO:0017166)
0.1 11.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 3.0 GO:0050681 androgen receptor binding(GO:0050681)
0.1 4.8 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.1 3.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 7.5 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 11.0 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 5.7 GO:0035064 methylated histone binding(GO:0035064)
0.1 2.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 7.6 GO:0043130 ubiquitin binding(GO:0043130)
0.1 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 0.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 3.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.6 GO:0035198 miRNA binding(GO:0035198)
0.1 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.2 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.1 1.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 1.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 5.0 GO:0003774 motor activity(GO:0003774)
0.0 2.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 5.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 13.5 GO:0005525 GTP binding(GO:0005525)
0.0 0.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 5.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.8 GO:0005518 collagen binding(GO:0005518)
0.0 2.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 3.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.9 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:1990430 G-protein coupled GABA receptor activity(GO:0004965) extracellular matrix protein binding(GO:1990430)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.8 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.1 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 3.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.9 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.3 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.3 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.6 GO:0004896 cytokine receptor activity(GO:0004896)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 14.3 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 7.8 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 5.7 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.2 1.9 PID_CONE_PATHWAY Visual signal transduction: Cones
0.2 4.0 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.2 0.9 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 1.0 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.1 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.2 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 4.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 3.3 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 4.0 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 4.3 PID_ATM_PATHWAY ATM pathway
0.1 3.7 PID_IL2_1PATHWAY IL2-mediated signaling events
0.1 3.5 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 2.0 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 1.7 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 2.6 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 11.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.2 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.1 4.1 PID_BMP_PATHWAY BMP receptor signaling
0.1 0.8 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.1 3.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 13.0 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 1.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 8.8 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.9 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 2.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 1.5 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.3 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.8 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.7 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 2.6 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 1.4 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.6 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.8 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.5 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.3 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.8 WNT_SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 17.0 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.7 22.7 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.5 12.5 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5 13.0 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.5 15.2 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.4 2.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.4 8.2 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.4 8.6 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.4 5.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 3.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.3 5.7 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.3 11.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.3 0.8 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.2 3.0 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 7.7 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.2 2.5 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 2.8 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 2.5 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 3.3 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 4.2 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.2 2.2 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 1.3 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 0.8 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 0.8 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 1.7 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 4.9 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 3.2 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 2.5 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 4.2 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.8 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 3.0 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.6 REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 0.9 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 2.6 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.3 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 0.9 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.8 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 2.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 1.2 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.0 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.5 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.1 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 0.3 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.8 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 6.7 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.6 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.4 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 2.5 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.1 3.2 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.9 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.1 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.1 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 3.4 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.1 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.2 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.4 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.9 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.3 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.4 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 2.2 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 1.2 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.4 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 1.0 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 2.2 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.5 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 0.7 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.2 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 1.8 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.7 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.1 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation