Motif ID: Ubp1

Z-value: 0.806


Transcription factors associated with Ubp1:

Gene SymbolEntrez IDGene Name
Ubp1 ENSMUSG00000009741.8 Ubp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ubp1mm10_v2_chr9_+_113930934_113930987-0.503.5e-06Click!


Activity profile for motif Ubp1.

activity profile for motif Ubp1


Sorted Z-values histogram for motif Ubp1

Sorted Z-values for motif Ubp1



Network of associatons between targets according to the STRING database.



First level regulatory network of Ubp1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_90772435 4.659 ENSMUST00000031320.6
 Pf4
platelet factor 4
chr1_-_75278345 4.108 ENSMUST00000039534.4
 Resp18
regulated endocrine-specific protein 18
chr6_-_23248264 3.771 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr6_-_91807318 3.315 ENSMUST00000159684.1
 Grip2
glutamate receptor interacting protein 2
chr14_-_37098211 2.946 ENSMUST00000022337.9
 Cdhr1
cadherin-related family member 1
chr3_+_67892189 2.908 ENSMUST00000063263.3
 Iqcj
IQ motif containing J
chr17_-_50094277 2.887 ENSMUST00000113195.1
 Rftn1
raftlin lipid raft linker 1
chr4_-_136898803 2.856 ENSMUST00000046285.5
 C1qa
complement component 1, q subcomponent, alpha polypeptide
chr5_-_44799643 2.853 ENSMUST00000070748.5
 Ldb2
LIM domain binding 2
chr3_+_106113229 2.720 ENSMUST00000079132.5
ENSMUST00000139086.1
 Chia

chitinase, acidic

chrY_+_897782 2.695 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr6_-_91807424 2.552 ENSMUST00000162300.1
 Grip2
glutamate receptor interacting protein 2
chr12_+_113152012 2.518 ENSMUST00000006523.7
 Crip1
cysteine-rich protein 1 (intestinal)
chr10_-_128549125 2.481 ENSMUST00000177163.1
ENSMUST00000176683.1
ENSMUST00000176010.1
 Rpl41


ribosomal protein L41


chr3_-_82145865 2.449 ENSMUST00000048976.6
 Gucy1a3
guanylate cyclase 1, soluble, alpha 3
chr10_+_14523062 2.441 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chr7_+_107567445 2.386 ENSMUST00000120990.1
 Olfml1
olfactomedin-like 1
chrX_+_73483602 2.294 ENSMUST00000033741.8
ENSMUST00000169489.1
 Bgn

biglycan

chr13_-_18031616 2.287 ENSMUST00000099736.2
 Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr10_+_79988584 2.239 ENSMUST00000004784.4
ENSMUST00000105374.1
 Cnn2

calponin 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 297 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.1 GO:0002181 cytoplasmic translation(GO:0002181)
1.2 6.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.6 5.8 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.9 4.7 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of cytolysis(GO:0045918)
0.5 4.4 GO:0071493 cellular response to UV-B(GO:0071493)
0.6 3.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 3.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 3.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.3 3.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 2.9 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 2.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 2.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.5 2.4 GO:0075136 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.0 2.4 GO:0045444 fat cell differentiation(GO:0045444)
0.4 2.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.3 2.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 2.2 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 2.2 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.7 2.1 GO:0016115 terpenoid catabolic process(GO:0016115)
0.4 2.1 GO:0032423 regulation of mismatch repair(GO:0032423)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 150 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.9 GO:0005615 extracellular space(GO:0005615)
0.1 10.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 8.4 GO:0043198 dendritic shaft(GO:0043198)
0.4 4.7 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 4.5 GO:0005581 collagen trimer(GO:0005581)
0.8 4.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 3.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 3.9 GO:0019866 organelle inner membrane(GO:0019866)
0.0 3.6 GO:0043197 dendritic spine(GO:0043197)
0.2 3.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 2.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 2.9 GO:0043209 myelin sheath(GO:0043209)
0.1 2.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.5 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 2.4 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 2.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.6 1.9 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 1.8 GO:0031143 pseudopodium(GO:0031143)
0.0 1.8 GO:0022627 small ribosomal subunit(GO:0015935) cytosolic small ribosomal subunit(GO:0022627)
0.0 1.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 201 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 13.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 7.5 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 5.3 GO:0003924 GTPase activity(GO:0003924)
0.9 4.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 4.7 GO:0070888 E-box binding(GO:0070888)
0.2 4.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 3.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 2.7 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 2.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 2.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.5 2.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 2.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 2.2 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.7 2.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.2 2.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 2.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 2.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.6 1.9 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 1.9 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.5 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.1 3.7 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 3.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 3.1 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 2.3 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 2.0 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.2 1.9 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.8 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 1.8 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 1.7 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 1.6 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 1.6 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.1 1.5 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.3 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.1 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.1 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.1 1.1 PID_LPA4_PATHWAY LPA4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 16.4 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 8.0 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.3 7.9 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.8 4.7 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 3.8 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 3.2 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.5 2.9 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.8 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 2.7 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 2.6 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 2.2 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.0 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 2.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 2.0 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.9 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.9 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.9 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.9 REACTOME_TRANSLATION Genes involved in Translation
0.1 1.7 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.7 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events