---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_139543889	143.139	ENSMUST00000174792.1 ENSMUST00000031523.8	Uncx	UNC homeobox
chr6_-_23248264	83.371	ENSMUST00000031709.5	Fezf1	Fez family zinc finger 1
chr10_+_73821857	25.159	ENSMUST00000177128.1 ENSMUST00000064562.7 ENSMUST00000129404.2 ENSMUST00000105426.3 ENSMUST00000131321.2 ENSMUST00000126920.2 ENSMUST00000147189.2 ENSMUST00000105424.3 ENSMUST00000092420.6 ENSMUST00000105429.3 ENSMUST00000131724.2 ENSMUST00000152655.2 ENSMUST00000151116.2 ENSMUST00000155701.2 ENSMUST00000152819.2 ENSMUST00000125517.2 ENSMUST00000124046.1 ENSMUST00000149977.2 ENSMUST00000146682.1 ENSMUST00000177107.1	Pcdh15	protocadherin 15
chr2_-_168767136	22.931	ENSMUST00000029061.5 ENSMUST00000103074.1	Sall4	sal-like 4 (Drosophila)
chr12_+_38780284	21.649	ENSMUST00000162563.1 ENSMUST00000161164.1 ENSMUST00000160996.1	Etv1	ets variant gene 1
chr12_+_38780817	20.351	ENSMUST00000160856.1	Etv1	ets variant gene 1
chr4_+_8690399	19.835	ENSMUST00000127476.1	Chd7	chromodomain helicase DNA binding protein 7
chr7_-_49636847	16.538	ENSMUST00000032717.6	Dbx1	developing brain homeobox 1
chr3_-_116253467	15.016	ENSMUST00000090473.5	Gpr88	G-protein coupled receptor 88
chr3_+_55782500	14.774	ENSMUST00000075422.4	Mab21l1	mab-21-like 1 (C. elegans)
chr17_-_70853482	13.742	ENSMUST00000118283.1	Tgif1	TGFB-induced factor homeobox 1
chr4_+_62583568	12.933	ENSMUST00000098031.3	Rgs3	regulator of G-protein signaling 3
chr2_-_168767029	12.846	ENSMUST00000075044.3	Sall4	sal-like 4 (Drosophila)
chr10_-_6980376	12.339	ENSMUST00000105617.1	Ipcef1	interaction protein for cytohesin exchange factors 1
chr17_+_43952999	11.845	ENSMUST00000177857.1	Rcan2	regulator of calcineurin 2
chrX_-_60893430	10.952	ENSMUST00000135107.2	Sox3	SRY-box containing gene 3
chr7_-_116031047	10.943	ENSMUST00000106612.1	Sox6	SRY-box containing gene 6
chr9_-_79977782	10.851	ENSMUST00000093811.4	Filip1	filamin A interacting protein 1
chr7_-_115846080	10.510	ENSMUST00000166207.1	Sox6	SRY-box containing gene 6
chr8_-_61902669	10.504	ENSMUST00000121785.1 ENSMUST00000034057.7	Palld	palladin, cytoskeletal associated protein
chr3_+_159839729	10.309	ENSMUST00000068952.5	Wls	wntless homolog (Drosophila)
chr12_+_38781093	10.000	ENSMUST00000161513.1	Etv1	ets variant gene 1
chr18_+_82914632	9.043	ENSMUST00000071233.6	Zfp516	zinc finger protein 516
chr1_+_109983737	8.971	ENSMUST00000172005.1	Cdh7	cadherin 7, type 2
chr8_-_45382198	7.913	ENSMUST00000093526.6	Fam149a	family with sequence similarity 149, member A
chr15_+_25773985	7.497	ENSMUST00000125667.1	Myo10	myosin X
chr4_-_132510493	7.448	ENSMUST00000030724.8	Sesn2	sestrin 2
chr14_-_48662740	7.204	ENSMUST00000122009.1	Otx2	orthodenticle homolog 2 (Drosophila)
chr8_-_57653023	7.043	ENSMUST00000034021.5	Galnt7	UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr3_-_88410295	7.007	ENSMUST00000056370.7	Pmf1	polyamine-modulated factor 1
chr4_-_129261394	6.977	ENSMUST00000145261.1	C77080	expressed sequence C77080
chr11_-_102579461	6.002	ENSMUST00000107081.1	Gm11627	predicted gene 11627
chr4_-_83285141	5.774	ENSMUST00000150522.1	Ttc39b	tetratricopeptide repeat domain 39B
chr9_+_75775355	5.504	ENSMUST00000012281.7	Bmp5	bone morphogenetic protein 5
chr2_-_121235689	5.482	ENSMUST00000142400.1	Trp53bp1	transformation related protein 53 binding protein 1
chr5_-_138187177	5.280	ENSMUST00000110937.1 ENSMUST00000139276.1 ENSMUST00000048698.7 ENSMUST00000123415.1	Taf6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_-_79456750	5.267	ENSMUST00000041099.4	Neurod1	neurogenic differentiation 1
chr1_-_172027269	5.148	ENSMUST00000027837.6 ENSMUST00000111264.1	Vangl2	vang-like 2 (van gogh, Drosophila)
chr3_+_5218546	5.068	ENSMUST00000026284.6	Zfhx4	zinc finger homeodomain 4
chr11_-_102579071	5.056	ENSMUST00000107080.1	Gm11627	predicted gene 11627
chr5_+_138187485	4.922	ENSMUST00000110934.2	Cnpy4	canopy 4 homolog (zebrafish)
chr3_-_154328634	4.877	ENSMUST00000167744.1	Lhx8	LIM homeobox protein 8
chr3_-_79841729	4.727	ENSMUST00000168038.1	Tmem144	transmembrane protein 144
chr4_-_45532470	4.701	ENSMUST00000147448.1	Shb	src homology 2 domain-containing transforming protein B
chr12_-_56535047	4.679	ENSMUST00000178477.2	Nkx2-1	NK2 homeobox 1
chr17_-_35697971	4.652	ENSMUST00000146472.1	Ddr1	discoidin domain receptor family, member 1
chr4_-_110286581	4.622	ENSMUST00000138972.1	Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr3_+_5218516	4.520	ENSMUST00000175866.1	Zfhx4	zinc finger homeodomain 4
chr16_-_45724600	4.278	ENSMUST00000096057.4	Tagln3	transgelin 3
chr11_+_62077018	4.231	ENSMUST00000092415.5	Specc1	sperm antigen with calponin homology and coiled-coil domains 1
chr5_-_98566762	4.219	ENSMUST00000086912.4	1700010H22Rik	RIKEN cDNA 1700010H22 gene
chr6_-_147264124	4.105	ENSMUST00000052296.6	Pthlh	parathyroid hormone-like peptide
chr4_-_110292719	4.031	ENSMUST00000106601.1	Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr12_-_31713873	3.999	ENSMUST00000057783.4 ENSMUST00000174480.2 ENSMUST00000176710.1	Gpr22	G protein-coupled receptor 22
chr1_-_172027251	3.853	ENSMUST00000138714.1	Vangl2	vang-like 2 (van gogh, Drosophila)
chr12_+_52699297	3.742	ENSMUST00000095737.3	Akap6	A kinase (PRKA) anchor protein 6
chr10_+_128337761	3.731	ENSMUST00000005826.7	Cs	citrate synthase
chr9_+_119063429	3.609	ENSMUST00000141185.1 ENSMUST00000126251.1 ENSMUST00000136561.1	Vill	villin-like
chr3_+_5218589	3.597	ENSMUST00000177488.1	Zfhx4	zinc finger homeodomain 4
chr2_-_59948155	3.489	ENSMUST00000153136.1	Baz2b	bromodomain adjacent to zinc finger domain, 2B
chr9_-_106891401	3.405	ENSMUST00000069036.7	Manf	mesencephalic astrocyte-derived neurotrophic factor
chr1_-_78968079	3.358	ENSMUST00000049117.5	Gm5830	predicted pseudogene 5830
chr17_-_70998010	3.195	ENSMUST00000024846.6	Myl12a	myosin, light chain 12A, regulatory, non-sarcomeric
chr1_+_132298606	3.149	ENSMUST00000046071.4	Klhdc8a	kelch domain containing 8A
chr3_+_76593550	3.058	ENSMUST00000162471.1	Fstl5	follistatin-like 5
chr1_-_79440039	3.046	ENSMUST00000049972.4	Scg2	secretogranin II
chr13_-_100616911	3.042	ENSMUST00000168772.1 ENSMUST00000163163.1 ENSMUST00000022137.7	Marveld2	MARVEL (membrane-associating) domain containing 2
chr12_+_109545390	2.843	ENSMUST00000146701.1	Meg3	maternally expressed 3
chr18_-_75697639	2.811	ENSMUST00000165559.1	Ctif	CBP80/20-dependent translation initiation factor
chr11_+_94327984	2.803	ENSMUST00000107818.2 ENSMUST00000051221.6	Ankrd40	ankyrin repeat domain 40
chr11_-_102185239	2.737	ENSMUST00000021297.5	Lsm12	LSM12 homolog (S. cerevisiae)
chr18_-_44662251	2.683	ENSMUST00000164666.1	Mcc	mutated in colorectal cancers
chr4_+_110397661	2.329	ENSMUST00000106589.2 ENSMUST00000106587.2 ENSMUST00000106591.1 ENSMUST00000106592.1	Agbl4	ATP/GTP binding protein-like 4
chr1_-_84839304	2.296	ENSMUST00000027421.6	Trip12	thyroid hormone receptor interactor 12
chr14_-_12345847	2.207	ENSMUST00000022262.4	Fezf2	Fez family zinc finger 2
chr7_+_123123870	2.164	ENSMUST00000094053.5	Tnrc6a	trinucleotide repeat containing 6a
chr5_+_27261916	2.128	ENSMUST00000101471.3	Dpp6	dipeptidylpeptidase 6
chr13_-_102906046	2.017	ENSMUST00000171791.1	Mast4	microtubule associated serine/threonine kinase family member 4
chr12_+_108605757	2.006	ENSMUST00000109854.2	Evl	Ena-vasodilator stimulated phosphoprotein
chr11_+_60537978	1.972	ENSMUST00000044250.3	Alkbh5	alkB, alkylation repair homolog 5 (E. coli)
chr6_+_73248382	1.967	ENSMUST00000064740.6	Suclg1	succinate-CoA ligase, GDP-forming, alpha subunit
chr13_-_102905740	1.962	ENSMUST00000167462.1	Mast4	microtubule associated serine/threonine kinase family member 4
chr4_-_41464816	1.916	ENSMUST00000108055.2 ENSMUST00000154535.1 ENSMUST00000030148.5	Kif24	kinesin family member 24
chrX_+_107255878	1.906	ENSMUST00000101294.2 ENSMUST00000118820.1 ENSMUST00000120971.1	Gpr174	G protein-coupled receptor 174
chr12_+_55598917	1.567	ENSMUST00000051857.3	Insm2	insulinoma-associated 2
chr8_-_84846860	1.487	ENSMUST00000003912.6	Calr	calreticulin
chr5_-_116288944	1.443	ENSMUST00000086483.3	Ccdc60	coiled-coil domain containing 60
chr14_-_122451109	1.419	ENSMUST00000081580.2	Gm5089	predicted gene 5089
chr15_+_81936911	1.407	ENSMUST00000135663.1	Csdc2	cold shock domain containing C2, RNA binding
chr4_+_110397764	1.389	ENSMUST00000097920.2 ENSMUST00000080744.6	Agbl4	ATP/GTP binding protein-like 4
chr1_+_10993452	1.358	ENSMUST00000027056.5	Prex2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chrM_+_7005	1.307	ENSMUST00000082405.1	mt-Co2	mitochondrially encoded cytochrome c oxidase II
chr10_-_86011833	1.053	ENSMUST00000105304.1 ENSMUST00000061699.5	Bpifc	BPI fold containing family C
chr7_-_5014645	1.020	ENSMUST00000165320.1	Fiz1	Flt3 interacting zinc finger protein 1
chr2_-_71055534	1.019	ENSMUST00000090849.5 ENSMUST00000100037.2 ENSMUST00000112186.2	Mettl8	methyltransferase like 8
chrX_+_140956892	0.987	ENSMUST00000112971.1	Atg4a	autophagy related 4A, cysteine peptidase
chr6_+_108065035	0.936	ENSMUST00000049246.6	Setmar	SET domain without mariner transposase fusion
chr5_-_137531952	0.931	ENSMUST00000140139.1	Gnb2	guanine nucleotide binding protein (G protein), beta 2
chr1_-_190170671	0.919	ENSMUST00000175916.1	Prox1	prospero-related homeobox 1
chr9_+_94669876	0.893	ENSMUST00000033463.9	Slc9a9	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr16_+_34690548	0.873	ENSMUST00000023532.6	Ccdc14	coiled-coil domain containing 14
chr1_-_182282738	0.853	ENSMUST00000035295.5	Degs1	degenerative spermatocyte homolog 1 (Drosophila)
chr9_-_21312255	0.827	ENSMUST00000115433.3 ENSMUST00000003397.7	Ap1m2	adaptor protein complex AP-1, mu 2 subunit
chr7_-_73541738	0.794	ENSMUST00000169922.2	Chd2	chromodomain helicase DNA binding protein 2
chr2_-_36136773	0.741	ENSMUST00000028251.3	Rbm18	RNA binding motif protein 18
chr10_+_127420867	0.694	ENSMUST00000064793.6	R3hdm2	R3H domain containing 2
chr12_-_56613270	0.683	ENSMUST00000072631.5	Nkx2-9	NK2 homeobox 9
chr9_-_65885024	0.643	ENSMUST00000122410.1 ENSMUST00000117083.1	Trip4	thyroid hormone receptor interactor 4
chr15_+_81744848	0.565	ENSMUST00000109554.1	Zc3h7b	zinc finger CCCH type containing 7B
chr2_+_9882622	0.530	ENSMUST00000114919.1	4930412O13Rik	RIKEN cDNA 4930412O13 gene
chr4_-_155056784	0.433	ENSMUST00000131173.2	Plch2	phospholipase C, eta 2
chr1_-_175491130	0.415	ENSMUST00000027812.5	Rgs7	regulator of G protein signaling 7
chr7_+_144838590	0.374	ENSMUST00000105898.1	Fgf3	fibroblast growth factor 3
chr3_+_122274371	0.331	ENSMUST00000035776.8	Dnttip2	deoxynucleotidyltransferase, terminal, interacting protein 2
chr19_+_5088534	0.214	ENSMUST00000025811.4	Yif1a	Yip1 interacting factor homolog A (S. cerevisiae)
chr16_-_89818338	0.197	ENSMUST00000164263.2	Tiam1	T cell lymphoma invasion and metastasis 1
chr1_+_66468364	0.184	ENSMUST00000061620.9	Unc80	unc-80 homolog (C. elegans)
chr8_-_120228221	0.140	ENSMUST00000183235.1	A330074K22Rik	RIKEN cDNA A330074K22 gene
chr10_-_53647080	0.101	ENSMUST00000169866.1	Fam184a	family with sequence similarity 184, member A
chr1_-_163725123	0.047	ENSMUST00000159679.1	Mettl11b	methyltransferase like 11B
chr9_-_71163224	0.041	ENSMUST00000074465.2	Aqp9	aquaporin 9
chr5_+_88583527	0.028	ENSMUST00000031229.6	Rufy3	RUN and FYVE domain containing 3
chr7_+_64185459	0.001	ENSMUST00000177102.2 ENSMUST00000107519.1 ENSMUST00000137650.1 ENSMUST00000032737.5 ENSMUST00000107515.1 ENSMUST00000144996.1	Trpm1	transient receptor potential cation channel, subfamily M, member 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
17.9	143.1	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
14.3	85.6	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
6.6	19.8	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
4.7	52.0	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
3.8	15.0	GO:0061743	motor learning(GO:0061743)
3.4	10.3	GO:0061357	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
3.1	25.2	GO:0050957	equilibrioception(GO:0050957)
3.0	9.0	GO:0060489	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
2.5	7.4	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
2.0	35.8	GO:0001833	inner cell mass cell proliferation(GO:0001833)
2.0	21.5	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
1.8	7.2	GO:0046552	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.8	5.3	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
1.6	4.7	GO:0021759	globus pallidus development(GO:0021759)
1.4	5.5	GO:0021502	neural fold elevation formation(GO:0021502)
1.1	3.4	GO:0002014	vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
1.0	15.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.9	3.7	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.9	3.7	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.9	16.5	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.8	2.3	GO:1902915	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.6	3.0	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.6	10.5	GO:0071803	keratinocyte development(GO:0003334) positive regulation of podosome assembly(GO:0071803)
0.5	11.0	GO:0007530	sex determination(GO:0007530)
0.5	4.7	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.5	2.0	GO:0035553	oxidative single-stranded RNA demethylation(GO:0035553)
0.5	4.1	GO:0043129	surfactant homeostasis(GO:0043129)
0.4	7.8	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.4	4.7	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.4	5.5	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4	4.7	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.3	2.0	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.3	0.9	GO:0090425	hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.3	2.0	GO:0006105	succinate metabolic process(GO:0006105)
0.2	3.7	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.2	9.0	GO:0050873	brown fat cell differentiation(GO:0050873)
0.2	1.0	GO:0051697	protein delipidation(GO:0051697)
0.1	7.0	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.1	2.2	GO:0045974	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1	2.8	GO:0008340	determination of adult lifespan(GO:0008340)
0.1	1.0	GO:0080009	mRNA methylation(GO:0080009)
0.1	9.9	GO:0043488	regulation of mRNA stability(GO:0043488)
0.1	3.6	GO:0051693	actin filament capping(GO:0051693)
0.1	0.9	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1	5.8	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.1	4.9	GO:0032880	regulation of protein localization(GO:0032880)
0.1	3.0	GO:0061028	establishment of endothelial barrier(GO:0061028)
0.1	2.8	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1	0.2	GO:1900149	positive regulation of Schwann cell migration(GO:1900149)
0.1	4.9	GO:0008585	female gonad development(GO:0008585)
0.0	0.8	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	1.9	GO:0043029	T cell homeostasis(GO:0043029)
0.0	2.7	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	2.1	GO:1903078	positive regulation of protein localization to plasma membrane(GO:1903078)
0.0	1.4	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.9	GO:0071539	protein localization to centrosome(GO:0071539)
0.0	1.9	GO:0007019	microtubule depolymerization(GO:0007019)
0.0	1.3	GO:0042773	ATP synthesis coupled electron transport(GO:0042773)
0.0	0.4	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.0	0.6	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	4.0	GO:0007059	chromosome segregation(GO:0007059)
0.0	0.0	GO:0046689	response to mercury ion(GO:0046689)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	9.0	GO:0060187	cell pole(GO:0060187)
1.2	7.0	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.8	7.4	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.8	4.9	GO:0001674	female germ cell nucleus(GO:0001674)
0.6	8.7	GO:0042788	polysomal ribosome(GO:0042788)
0.5	25.2	GO:0032420	stereocilium(GO:0032420)
0.5	3.0	GO:0061689	paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)
0.3	2.0	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.3	5.3	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.3	35.8	GO:0000792	heterochromatin(GO:0000792)
0.2	10.3	GO:0032590	dendrite membrane(GO:0032590)
0.2	2.2	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.2	10.5	GO:0002102	podosome(GO:0002102)
0.2	3.7	GO:0005640	nuclear outer membrane(GO:0005640)
0.2	3.0	GO:0031045	dense core granule(GO:0031045)
0.2	1.5	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.2	10.7	GO:0016459	myosin complex(GO:0016459)
0.2	5.5	GO:0035861	site of double-strand break(GO:0035861)
0.1	1.3	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.1	0.9	GO:0034451	centriolar satellite(GO:0034451)
0.1	4.1	GO:0005814	centriole(GO:0005814)
0.1	3.0	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	26.3	GO:0005667	transcription factor complex(GO:0005667)
0.0	349.7	GO:0005634	nucleus(GO:0005634)
0.0	0.8	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	2.0	GO:0030027	lamellipodium(GO:0030027)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	7.8	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.2	7.4	GO:0070728	leucine binding(GO:0070728)
1.0	10.3	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.9	5.5	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.7	2.0	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.6	13.7	GO:0070410	co-SMAD binding(GO:0070410)
0.6	3.7	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.6	7.0	GO:0043522	leucine zipper domain binding(GO:0043522)
0.6	19.8	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.6	5.5	GO:0070700	BMP receptor binding(GO:0070700)
0.5	5.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.5	4.7	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.5	4.7	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.5	93.9	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.5	2.0	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.4	4.1	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.4	7.0	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3	11.0	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.3	0.9	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.3	3.7	GO:0043495	protein anchor(GO:0043495)
0.3	259.3	GO:0043565	sequence-specific DNA binding(GO:0043565)
0.2	8.7	GO:0017091	AU-rich element binding(GO:0017091)
0.2	24.4	GO:0003774	motor activity(GO:0003774)
0.2	25.2	GO:0047485	protein N-terminus binding(GO:0047485)
0.2	2.0	GO:0005522	profilin binding(GO:0005522)
0.2	2.3	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.1	1.9	GO:0045125	bioactive lipid receptor activity(GO:0045125)
0.1	1.9	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	14.8	GO:0016779	nucleotidyltransferase activity(GO:0016779)
0.1	4.0	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	0.9	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.1	4.8	GO:0015144	carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.1	1.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.1	1.5	GO:0050681	androgen receptor binding(GO:0050681)
0.1	1.3	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	7.9	GO:0051015	actin filament binding(GO:0051015)
0.0	2.1	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	3.2	GO:0035254	glutamate receptor binding(GO:0035254)
0.0	0.9	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.4	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	3.0	GO:0005125	cytokine activity(GO:0005125)
0.0	1.2	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	2.2	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	1.2	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.6	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	1.6	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	1.0	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	2.7	GO:0000287	magnesium ion binding(GO:0000287)
0.0	2.8	GO:0003779	actin binding(GO:0003779)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	52.0	PID_P38_MK2_PATHWAY	p38 signaling mediated by MAPKAP kinases
0.4	19.8	PID_WNT_NONCANONICAL_PATHWAY	Noncanonical Wnt signaling pathway
0.4	13.1	PID_EPHRINB_REV_PATHWAY	Ephrin B reverse signaling
0.4	12.3	SA_PTEN_PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3	30.7	PID_BETA_CATENIN_NUC_PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.3	7.8	PID_TCR_CALCIUM_PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.2	7.5	PID_NETRIN_PATHWAY	Netrin-mediated signaling events
0.2	4.7	PID_PDGFRA_PATHWAY	PDGFR-alpha signaling pathway
0.2	4.1	PID_HEDGEHOG_2PATHWAY	Signaling events mediated by the Hedgehog family
0.2	13.7	PID_AR_PATHWAY	Coregulation of Androgen receptor activity
0.1	4.7	PID_HNF3B_PATHWAY	FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	13.7	REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3	5.7	REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.3	9.0	REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS	Genes involved in Adherens junctions interactions
0.2	5.3	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS	Genes involved in Regulation of gene expression in beta cells
0.2	2.2	REACTOME_REGULATORY_RNA_PATHWAYS	Genes involved in Regulatory RNA pathways
0.2	7.0	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	Genes involved in O-linked glycosylation of mucins
0.2	1.5	REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	2.0	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES	Genes involved in Generation of second messenger molecules
0.1	7.5	REACTOME_NETRIN1_SIGNALING	Genes involved in Netrin-1 signaling
0.1	5.3	REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1	7.0	REACTOME_MITOTIC_PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	0.8	REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	3.8	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.9	REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis

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