Motif ID: Xbp1_Creb3l1

Z-value: 0.973

Transcription factors associated with Xbp1_Creb3l1:

Gene SymbolEntrez IDGene Name
Creb3l1 ENSMUSG00000027230.9 Creb3l1
Xbp1 ENSMUSG00000020484.12 Xbp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb3l1mm10_v2_chr2_-_92024502_920245290.561.0e-07Click!
Xbp1mm10_v2_chr11_+_5520652_5520659-0.252.7e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Xbp1_Creb3l1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_45092130 21.622 ENSMUST00000148175.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr7_-_45092198 18.831 ENSMUST00000140449.1
ENSMUST00000117546.1
ENSMUST00000019683.3
Rcn3


reticulocalbin 3, EF-hand calcium binding domain


chr7_-_45091713 12.318 ENSMUST00000141576.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr6_-_54593139 9.658 ENSMUST00000046520.6
Fkbp14
FK506 binding protein 14
chr15_-_32244632 8.801 ENSMUST00000181536.1
0610007N19Rik
RIKEN cDNA 0610007N19
chr4_+_88094599 6.659 ENSMUST00000097992.3
Focad
focadhesin
chr1_-_55226768 6.322 ENSMUST00000027121.8
ENSMUST00000114428.2
Rftn2

raftlin family member 2

chr5_-_135251209 5.864 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr15_+_79516396 5.723 ENSMUST00000010974.7
Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr10_+_128908907 5.030 ENSMUST00000105229.1
Cd63
CD63 antigen
chr8_+_125995102 4.724 ENSMUST00000046765.8
Kcnk1
potassium channel, subfamily K, member 1
chr3_+_96697076 4.456 ENSMUST00000162778.2
ENSMUST00000064900.9
Pias3

protein inhibitor of activated STAT 3

chr3_+_96697100 4.349 ENSMUST00000107077.3
Pias3
protein inhibitor of activated STAT 3
chr1_-_163313661 3.849 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1


paired related homeobox 1


chr6_-_101377342 3.782 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr10_+_41519493 3.549 ENSMUST00000019962.8
Cd164
CD164 antigen
chr5_-_71095765 3.529 ENSMUST00000000572.5
Gabra2
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
chrX_+_136741821 3.410 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr3_+_88206786 3.364 ENSMUST00000181134.1
ENSMUST00000181550.1
Gm3764

predicted gene 3764

chr3_+_88207308 3.109 ENSMUST00000180582.1
Gm3764
predicted gene 3764
chrX_+_56454871 3.052 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr17_-_25785324 2.906 ENSMUST00000150324.1
Haghl
hydroxyacylglutathione hydrolase-like
chr3_+_93520473 2.899 ENSMUST00000029515.4
S100a11
S100 calcium binding protein A11 (calgizzarin)
chr2_-_105399286 2.762 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr6_+_29348069 2.697 ENSMUST00000173216.1
ENSMUST00000031779.10
ENSMUST00000090481.7
Calu


calumenin


chr2_-_79428891 2.651 ENSMUST00000143974.1
Cerkl
ceramide kinase-like
chr2_+_80315461 2.606 ENSMUST00000028392.7
Dnajc10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr17_-_47833169 2.593 ENSMUST00000131971.1
ENSMUST00000129360.1
ENSMUST00000113280.1
ENSMUST00000132125.1
Mdfi



MyoD family inhibitor



chr11_-_100970887 2.587 ENSMUST00000060792.5
Ptrf
polymerase I and transcript release factor
chr11_-_69948145 2.566 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
Slc2a4




solute carrier family 2 (facilitated glucose transporter), member 4




chr17_-_47833256 2.542 ENSMUST00000152455.1
ENSMUST00000035375.7
Mdfi

MyoD family inhibitor

chr4_-_134000857 2.430 ENSMUST00000105887.1
ENSMUST00000012262.5
ENSMUST00000144668.1
ENSMUST00000105889.3
Dhdds



dehydrodolichyl diphosphate synthase



chr15_-_57892358 2.404 ENSMUST00000022993.5
Derl1
Der1-like domain family, member 1
chr9_+_57560934 2.337 ENSMUST00000045791.9
Scamp2
secretory carrier membrane protein 2
chr17_-_51831884 2.262 ENSMUST00000124222.1
Satb1
special AT-rich sequence binding protein 1
chr16_+_36875119 2.262 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
Golgb1


Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1


golgi autoantigen, golgin subfamily b, macrogolgin 1
chr10_+_91082940 2.221 ENSMUST00000020150.3
Ikbip
IKBKB interacting protein
chr7_+_24904384 2.221 ENSMUST00000117419.1
Arhgef1
Rho guanine nucleotide exchange factor (GEF) 1
chr9_-_32541589 2.202 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr18_-_52529692 2.094 ENSMUST00000025409.7
Lox
lysyl oxidase
chr2_+_164497518 2.077 ENSMUST00000103101.4
ENSMUST00000117066.1
Pigt

phosphatidylinositol glycan anchor biosynthesis, class T

chr19_+_8741473 2.055 ENSMUST00000177373.1
ENSMUST00000010254.9
Stx5a

syntaxin 5A

chr5_-_35679416 2.025 ENSMUST00000114233.2
Htra3
HtrA serine peptidase 3
chr19_+_8741413 2.000 ENSMUST00000176381.1
Stx5a
syntaxin 5A
chr13_-_76098606 1.880 ENSMUST00000120573.1
Arsk
arylsulfatase K
chr4_-_108406676 1.815 ENSMUST00000184609.1
Gpx7
glutathione peroxidase 7
chr3_-_84582476 1.802 ENSMUST00000107687.2
ENSMUST00000098990.3
Arfip1

ADP-ribosylation factor interacting protein 1

chr3_-_84582616 1.783 ENSMUST00000143514.1
Arfip1
ADP-ribosylation factor interacting protein 1
chr9_+_57504012 1.636 ENSMUST00000080514.7
Rpp25
ribonuclease P/MRP 25 subunit
chr11_+_3514861 1.630 ENSMUST00000094469.4
Selm
selenoprotein M
chr10_+_91083036 1.624 ENSMUST00000020149.5
Ikbip
IKBKB interacting protein
chr4_-_43562397 1.618 ENSMUST00000030187.7
Tln1
talin 1
chr10_-_18743691 1.566 ENSMUST00000019999.5
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr19_+_46761578 1.564 ENSMUST00000077666.4
ENSMUST00000099373.4
Cnnm2

cyclin M2

chr10_+_81136223 1.563 ENSMUST00000048128.8
Zbtb7a
zinc finger and BTB domain containing 7a
chr9_-_89705017 1.547 ENSMUST00000058488.6
Tmed3
transmembrane emp24 domain containing 3
chr10_+_81136534 1.521 ENSMUST00000119606.1
ENSMUST00000146895.1
ENSMUST00000121840.1
Zbtb7a


zinc finger and BTB domain containing 7a


chr15_-_10470490 1.516 ENSMUST00000136591.1
Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr7_+_128523576 1.495 ENSMUST00000033136.7
Bag3
BCL2-associated athanogene 3
chr7_-_142578139 1.462 ENSMUST00000136359.1
H19
H19 fetal liver mRNA
chr7_-_45211877 1.429 ENSMUST00000033057.7
Dkkl1
dickkopf-like 1
chr5_+_64970069 1.413 ENSMUST00000031080.8
Fam114a1
family with sequence similarity 114, member A1
chr18_-_52529847 1.411 ENSMUST00000171470.1
Lox
lysyl oxidase
chr19_+_5088534 1.406 ENSMUST00000025811.4
Yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr7_-_142578093 1.378 ENSMUST00000149974.1
ENSMUST00000152754.1
H19

H19 fetal liver mRNA

chr19_+_11965817 1.372 ENSMUST00000025590.9
Osbp
oxysterol binding protein
chr2_-_39065505 1.371 ENSMUST00000039165.8
Golga1
golgi autoantigen, golgin subfamily a, 1
chr9_+_104063376 1.260 ENSMUST00000120854.1
Acad11
acyl-Coenzyme A dehydrogenase family, member 11
chr2_+_150786735 1.252 ENSMUST00000045441.7
Pygb
brain glycogen phosphorylase
chr4_-_129640959 1.236 ENSMUST00000132217.1
ENSMUST00000130017.1
ENSMUST00000154105.1
Txlna


taxilin alpha


chr13_-_37994111 1.226 ENSMUST00000021864.6
Ssr1
signal sequence receptor, alpha
chr5_+_30869579 1.218 ENSMUST00000046349.7
Tmem214
transmembrane protein 214
chr10_+_85102627 1.217 ENSMUST00000095383.4
AI597468
expressed sequence AI597468
chr2_-_91070180 1.196 ENSMUST00000153367.1
ENSMUST00000079976.3
Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr4_-_155653184 1.194 ENSMUST00000030937.1
Mmp23
matrix metallopeptidase 23
chr10_+_42761483 1.188 ENSMUST00000019937.4
Sec63
SEC63-like (S. cerevisiae)
chr19_+_8741669 1.141 ENSMUST00000176314.1
ENSMUST00000073430.7
ENSMUST00000175901.1
Stx5a


syntaxin 5A


chr7_+_82867327 1.136 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr3_+_144570409 1.131 ENSMUST00000082437.3
Sep15
selenoprotein
chr12_+_59130767 1.082 ENSMUST00000175877.1
Ctage5
CTAGE family, member 5
chr2_-_91070283 1.074 ENSMUST00000111436.2
ENSMUST00000073575.5
Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr9_-_42472198 1.057 ENSMUST00000128959.1
ENSMUST00000066148.5
ENSMUST00000138506.1
Tbcel


tubulin folding cofactor E-like


chr5_-_72559599 1.034 ENSMUST00000074948.4
ENSMUST00000087216.5
Nfxl1

nuclear transcription factor, X-box binding-like 1

chr12_+_88953399 1.024 ENSMUST00000057634.7
Nrxn3
neurexin III
chr11_-_72795801 1.007 ENSMUST00000079681.5
Cyb5d2
cytochrome b5 domain containing 2
chr11_-_72796028 1.006 ENSMUST00000156294.1
Cyb5d2
cytochrome b5 domain containing 2
chr10_-_84533884 1.004 ENSMUST00000053871.3
Ckap4
cytoskeleton-associated protein 4
chr12_+_33957645 1.002 ENSMUST00000049089.5
Twist1
twist basic helix-loop-helix transcription factor 1
chr5_+_30869623 0.993 ENSMUST00000114716.1
Tmem214
transmembrane protein 214
chr3_+_144570687 0.983 ENSMUST00000106211.1
Sep15
selenoprotein
chr8_+_71366848 0.961 ENSMUST00000110053.2
ENSMUST00000110054.1
ENSMUST00000139541.1
Use1


unconventional SNARE in the ER 1 homolog (S. cerevisiae)


chr9_-_103202113 0.959 ENSMUST00000035157.8
Srprb
signal recognition particle receptor, B subunit
chr4_+_44756553 0.937 ENSMUST00000107824.2
Zcchc7
zinc finger, CCHC domain containing 7
chr13_-_38528412 0.934 ENSMUST00000035988.8
Txndc5
thioredoxin domain containing 5
chr6_-_88518760 0.906 ENSMUST00000032168.5
Sec61a1
Sec61 alpha 1 subunit (S. cerevisiae)
chr10_-_84533968 0.899 ENSMUST00000167671.1
Ckap4
cytoskeleton-associated protein 4
chr19_+_8898090 0.899 ENSMUST00000096246.3
Ganab
alpha glucosidase 2 alpha neutral subunit
chr9_-_21091974 0.880 ENSMUST00000115487.1
Raver1
ribonucleoprotein, PTB-binding 1
chr7_-_118491912 0.869 ENSMUST00000178344.1
Itpripl2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr8_+_71367210 0.858 ENSMUST00000019169.7
Use1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr11_-_88718078 0.852 ENSMUST00000092794.5
Msi2
musashi RNA-binding protein 2
chr4_-_129640691 0.800 ENSMUST00000084264.5
Txlna
taxilin alpha
chr4_+_137594140 0.752 ENSMUST00000105840.1
ENSMUST00000055131.6
ENSMUST00000105839.1
ENSMUST00000105838.1
Usp48



ubiquitin specific peptidase 48



chr2_+_121140407 0.751 ENSMUST00000028702.3
ENSMUST00000110665.1
Adal

adenosine deaminase-like

chr1_-_13589717 0.736 ENSMUST00000027068.4
Tram1
translocating chain-associating membrane protein 1
chr7_-_44869788 0.734 ENSMUST00000046575.9
Ptov1
prostate tumor over expressed gene 1
chr1_-_172082757 0.733 ENSMUST00000003550.4
Ncstn
nicastrin
chr1_+_92910758 0.724 ENSMUST00000027487.8
Rnpepl1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr1_-_75479271 0.722 ENSMUST00000079205.7
ENSMUST00000094818.2
Chpf

chondroitin polymerizing factor

chr13_+_76098734 0.721 ENSMUST00000091466.3
Ttc37
tetratricopeptide repeat domain 37
chr2_+_121140498 0.714 ENSMUST00000119031.1
ENSMUST00000110662.2
Adal

adenosine deaminase-like

chr2_-_157204483 0.698 ENSMUST00000029170.7
Rbl1
retinoblastoma-like 1 (p107)
chr4_+_44756609 0.676 ENSMUST00000143385.1
Zcchc7
zinc finger, CCHC domain containing 7
chrX_+_56346390 0.664 ENSMUST00000101560.3
Zfp449
zinc finger protein 449
chr11_-_96916366 0.657 ENSMUST00000144731.1
ENSMUST00000127048.1
Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr11_-_96916448 0.657 ENSMUST00000103152.4
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr13_-_100833369 0.656 ENSMUST00000067246.4
Slc30a5
solute carrier family 30 (zinc transporter), member 5
chr2_-_155692317 0.629 ENSMUST00000103140.4
Trpc4ap
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr4_-_137796350 0.623 ENSMUST00000030551.4
Alpl
alkaline phosphatase, liver/bone/kidney
chr11_-_96916407 0.601 ENSMUST00000130774.1
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chrX_+_73787002 0.570 ENSMUST00000166518.1
Ssr4
signal sequence receptor, delta
chrX_+_73787062 0.561 ENSMUST00000002090.2
Ssr4
signal sequence receptor, delta
chr4_-_47474283 0.557 ENSMUST00000044148.2
Alg2
asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase)
chr16_-_32877723 0.547 ENSMUST00000119810.1
1700021K19Rik
RIKEN cDNA 1700021K19 gene
chr14_-_79301623 0.533 ENSMUST00000022595.7
Rgcc
regulator of cell cycle
chr9_-_73039644 0.532 ENSMUST00000184389.1
Pigb
phosphatidylinositol glycan anchor biosynthesis, class B
chr1_-_183369529 0.523 ENSMUST00000069922.5
Mia3
melanoma inhibitory activity 3
chr5_+_113735782 0.490 ENSMUST00000065698.5
Ficd
FIC domain containing
chr15_+_76701455 0.473 ENSMUST00000019224.7
Mfsd3
major facilitator superfamily domain containing 3
chr1_+_119526125 0.473 ENSMUST00000183952.1
TMEM185B
Transmembrane protein 185B
chr19_+_6909722 0.471 ENSMUST00000116551.3
Trmt112
tRNA methyltransferase 11-2
chr19_+_6909692 0.470 ENSMUST00000088257.7
Trmt112
tRNA methyltransferase 11-2
chr14_-_75754475 0.452 ENSMUST00000049168.7
Cog3
component of oligomeric golgi complex 3
chr3_-_107696462 0.443 ENSMUST00000029490.8
Ahcyl1
S-adenosylhomocysteine hydrolase-like 1
chr1_+_93215899 0.422 ENSMUST00000138595.1
E030010N08Rik
RIKEN cDNA E030010N08 gene
chr12_+_13269111 0.421 ENSMUST00000042953.8
Nbas
neuroblastoma amplified sequence
chr17_+_34032071 0.409 ENSMUST00000174299.1
ENSMUST00000173554.1
Rxrb

retinoid X receptor beta

chr17_+_29490812 0.405 ENSMUST00000024811.6
Pim1
proviral integration site 1
chr1_+_36471590 0.388 ENSMUST00000153128.1
Cnnm4
cyclin M4
chr7_-_127393604 0.387 ENSMUST00000165495.1
ENSMUST00000106303.2
ENSMUST00000074249.6
E430018J23Rik


RIKEN cDNA E430018J23 gene


chr1_+_92831614 0.386 ENSMUST00000045970.6
Gpc1
glypican 1
chr11_+_54100924 0.379 ENSMUST00000093107.5
ENSMUST00000019050.5
ENSMUST00000174616.1
ENSMUST00000129499.1
ENSMUST00000126840.1
P4ha2




procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide




chr16_-_36874806 0.367 ENSMUST00000075946.5
Eaf2
ELL associated factor 2
chr6_-_113740675 0.360 ENSMUST00000032440.4
Sec13
SEC13 homolog (S. cerevisiae)
chr4_-_129641060 0.359 ENSMUST00000046425.9
ENSMUST00000133803.1
Txlna

taxilin alpha

chr4_+_153957230 0.348 ENSMUST00000058393.2
ENSMUST00000105645.2
A430005L14Rik

RIKEN cDNA A430005L14 gene

chr5_+_124541296 0.347 ENSMUST00000124529.1
Tmed2
transmembrane emp24 domain trafficking protein 2
chr11_-_116274102 0.342 ENSMUST00000106425.3
Srp68
signal recognition particle 68
chrX_-_73786888 0.334 ENSMUST00000052761.8
Idh3g
isocitrate dehydrogenase 3 (NAD+), gamma
chr3_-_65392546 0.333 ENSMUST00000119896.1
Ssr3
signal sequence receptor, gamma
chr13_-_74376566 0.328 ENSMUST00000091481.2
Zfp72
zinc finger protein 72
chr4_-_11386757 0.322 ENSMUST00000108313.1
ENSMUST00000108311.2
Esrp1

epithelial splicing regulatory protein 1

chr7_+_49910112 0.311 ENSMUST00000056442.5
Slc6a5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr2_-_121140649 0.282 ENSMUST00000110674.2
Lcmt2
leucine carboxyl methyltransferase 2
chr13_-_55321928 0.274 ENSMUST00000035242.7
Rab24
RAB24, member RAS oncogene family
chr5_+_137288273 0.269 ENSMUST00000024099.4
ENSMUST00000085934.3
Ache

acetylcholinesterase

chr7_-_127387113 0.264 ENSMUST00000164345.1
ENSMUST00000049052.3
9130019O22Rik

RIKEN cDNA 9130019O22 gene

chr9_+_72925622 0.243 ENSMUST00000038489.5
Pygo1
pygopus 1
chr4_-_151861762 0.230 ENSMUST00000097774.2
Camta1
calmodulin binding transcription activator 1
chr4_-_151861698 0.206 ENSMUST00000049790.7
Camta1
calmodulin binding transcription activator 1
chr17_-_56183887 0.203 ENSMUST00000019723.7
D17Wsu104e
DNA segment, Chr 17, Wayne State University 104, expressed
chr7_-_121035096 0.197 ENSMUST00000065740.2
Gm9905
predicted gene 9905
chr11_-_116274197 0.190 ENSMUST00000021133.9
Srp68
signal recognition particle 68
chr2_-_121140371 0.182 ENSMUST00000099486.2
Lcmt2
leucine carboxyl methyltransferase 2
chr15_-_76918010 0.175 ENSMUST00000048854.7
Zfp647
zinc finger protein 647
chr17_+_34031787 0.169 ENSMUST00000044858.8
Rxrb
retinoid X receptor beta
chr10_+_61680302 0.161 ENSMUST00000020285.8
Sar1a
SAR1 gene homolog A (S. cerevisiae)
chr4_+_153957247 0.155 ENSMUST00000141493.1
A430005L14Rik
RIKEN cDNA A430005L14 gene
chr3_-_108086590 0.151 ENSMUST00000102638.1
ENSMUST00000102637.1
Ampd2

adenosine monophosphate deaminase 2

chr19_-_41263931 0.144 ENSMUST00000025989.8
Tm9sf3
transmembrane 9 superfamily member 3
chr8_-_70700070 0.141 ENSMUST00000116172.1
Gm11175
predicted gene 11175
chr18_+_65581704 0.139 ENSMUST00000182979.1
Zfp532
zinc finger protein 532
chr5_-_115158169 0.136 ENSMUST00000053271.5
ENSMUST00000112121.1
Mlec

malectin

chr14_-_26638183 0.127 ENSMUST00000166902.1
4930570N19Rik
RIKEN cDNA 4930570N19 gene
chr7_+_127912510 0.111 ENSMUST00000033070.7
Kat8
K(lysine) acetyltransferase 8
chr17_-_25861456 0.106 ENSMUST00000079461.8
ENSMUST00000176923.1
Wdr90

WD repeat domain 90

chr9_+_44379490 0.099 ENSMUST00000066601.6
Hyou1
hypoxia up-regulated 1
chr10_+_81176631 0.086 ENSMUST00000047864.9
Eef2
eukaryotic translation elongation factor 2
chr1_+_172082509 0.077 ENSMUST00000135192.1
Copa
coatomer protein complex subunit alpha
chr13_+_72628831 0.074 ENSMUST00000169028.1
Irx2
Iroquois related homeobox 2 (Drosophila)
chr1_+_172082796 0.072 ENSMUST00000027833.5
Copa
coatomer protein complex subunit alpha
chr3_+_58525821 0.071 ENSMUST00000029387.8
Eif2a
eukaryotic translation initiation factor 2A
chr6_-_82774448 0.023 ENSMUST00000000642.4
Hk2
hexokinase 2
chr9_+_44379536 0.018 ENSMUST00000161318.1
ENSMUST00000160902.1
Hyou1

hypoxia up-regulated 1

chr11_+_82781108 0.009 ENSMUST00000092849.5
ENSMUST00000021039.5
ENSMUST00000080461.5
ENSMUST00000173347.1
ENSMUST00000173727.1
ENSMUST00000173009.1
ENSMUST00000131537.2
ENSMUST00000173722.1
Lig3







ligase III, DNA, ATP-dependent







chr6_+_83115495 0.005 ENSMUST00000032114.7
Mogs
mannosyl-oligosaccharide glucosidase
chr2_+_31572775 0.003 ENSMUST00000137889.1
Fubp3
far upstream element (FUSE) binding protein 3
chr8_+_70302761 0.002 ENSMUST00000150968.1
Cope
coatomer protein complex, subunit epsilon

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:1990523 bone regeneration(GO:1990523)
1.0 5.0 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.9 6.3 GO:0032596 protein transport into membrane raft(GO:0032596) dsRNA transport(GO:0033227)
0.8 4.7 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.8 5.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.6 5.2 GO:0090166 Golgi disassembly(GO:0090166)
0.5 8.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.5 1.5 GO:0006154 adenosine catabolic process(GO:0006154)
0.4 3.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 2.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.3 1.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) regulation of oxidative phosphorylation uncoupler activity(GO:2000275) cell proliferation involved in heart valve development(GO:2000793)
0.3 2.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.3 0.9 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.3 3.8 GO:0048664 neuron fate determination(GO:0048664)
0.3 2.9 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.3 5.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.3 2.4 GO:0016093 polyprenol metabolic process(GO:0016093)
0.3 2.8 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 1.6 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 0.5 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.2 1.1 GO:0072697 protein localization to cell cortex(GO:0072697)
0.2 1.9 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.2 0.5 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 3.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 1.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 2.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.9 GO:0006620 posttranslational protein targeting to membrane(GO:0006620) pronephros development(GO:0048793)
0.1 0.4 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 3.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.9 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 1.9 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 2.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.3 GO:0036233 glycine import(GO:0036233)
0.1 2.6 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.1 8.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 1.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 2.2 GO:0035855 megakaryocyte development(GO:0035855)
0.1 1.5 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.7 GO:0061088 cobalt ion transport(GO:0006824) sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.4 GO:0042045 epithelial fluid transport(GO:0042045)
0.1 1.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.4 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 3.8 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 3.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 1.0 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.7 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.8 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 3.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.5 GO:0097502 mannosylation(GO:0097502)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.3 GO:0019695 choline metabolic process(GO:0019695) neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.5 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 2.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 2.7 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0072015 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.6 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 0.6 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.4 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.1 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 2.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.3 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 2.4 GO:0042113 B cell activation(GO:0042113)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.4 GO:0050885 neuromuscular process controlling balance(GO:0050885)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
1.2 4.7 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.4 3.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.3 2.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.3 1.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 0.7 GO:0055087 Ski complex(GO:0055087)
0.2 3.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 5.4 GO:0031527 filopodium membrane(GO:0031527)
0.2 2.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 5.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 2.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.5 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 3.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 4.6 GO:0031201 SNARE complex(GO:0031201)
0.1 2.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 2.2 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 3.8 GO:0005844 polysome(GO:0005844)
0.0 3.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 3.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 64.0 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 1.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 4.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.5 GO:0030018 Z disc(GO:0030018)
0.0 7.9 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0 5.3 GO:0030425 dendrite(GO:0030425)
0.0 2.0 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.9 2.7 GO:0001729 ceramide kinase activity(GO:0001729)
0.9 3.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.6 2.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.6 3.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.5 1.8 GO:0004096 catalase activity(GO:0004096)
0.4 4.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.4 8.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 1.3 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.3 2.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.3 2.9 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.3 1.3 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.3 8.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.3 5.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 0.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 1.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.2 0.6 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.2 1.6 GO:0030274 LIM domain binding(GO:0030274)
0.2 0.5 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.2 2.6 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.2 1.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 0.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 5.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 2.4 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 1.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.9 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 1.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 3.8 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.5 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 5.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 2.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 2.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 3.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.6 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 44.9 GO:0005509 calcium ion binding(GO:0005509)
0.1 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.3 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 2.0 GO:0020037 heme binding(GO:0020037)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.0 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.8 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.2 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 2.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 1.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.9 GO:0008276 protein methyltransferase activity(GO:0008276)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.8 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.2 5.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 4.4 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 1.6 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.4 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.7 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 5.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 1.0 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 3.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.6 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID_ATF2_PATHWAY ATF-2 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.7 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.4 20.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 1.9 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 2.6 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 3.5 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 1.5 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.6 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 0.9 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.3 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 5.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.1 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 2.6 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 0.7 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 4.3 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.4 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 2.2 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.6 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.1 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage