Motif ID: Ybx1_Nfya_Nfyb_Nfyc_Cebpz

Z-value: 8.624


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfycmm10_v2_chr4_-_120815703_1208157610.503.0e-06Click!
Ybx1mm10_v2_chr4_-_119294520_119294604-0.351.6e-03Click!
Cebpzmm10_v2_chr17_-_78937031_78937074-0.262.3e-02Click!
Nfybmm10_v2_chr10_-_82764088_82764144-0.103.8e-01Click!
Nfyamm10_v2_chr17_-_48409729_48409906-0.047.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Ybx1_Nfya_Nfyb_Nfyc_Cebpz

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_99024179 181.828 ENSMUST00000068031.7
Top2a
topoisomerase (DNA) II alpha
chr6_+_124829582 156.759 ENSMUST00000024270.7
Cdca3
cell division cycle associated 3
chr8_+_57511833 135.963 ENSMUST00000067925.6
Hmgb2
high mobility group box 2
chr8_+_83955507 132.675 ENSMUST00000005607.8
Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr3_-_27153861 129.495 ENSMUST00000108300.1
ENSMUST00000108298.2
Ect2

ect2 oncogene

chr14_-_67715585 127.072 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2


cell division cycle associated 2


chr1_+_139454747 125.859 ENSMUST00000053364.8
ENSMUST00000097554.3
Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr3_-_27153844 124.476 ENSMUST00000176242.2
ENSMUST00000176780.1
Ect2

ect2 oncogene

chr3_-_27153782 118.976 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
Ect2


ect2 oncogene


chr9_+_118478182 112.710 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr11_-_87108656 111.711 ENSMUST00000051395.8
Prr11
proline rich 11
chr14_+_46760526 109.548 ENSMUST00000067426.4
Cdkn3
cyclin-dependent kinase inhibitor 3
chr15_+_99074968 109.232 ENSMUST00000039665.6
Troap
trophinin associated protein
chr9_+_118478344 107.306 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr6_+_124829540 107.076 ENSMUST00000150120.1
Cdca3
cell division cycle associated 3
chr6_+_124830217 103.994 ENSMUST00000131847.1
ENSMUST00000151674.1
Cdca3

cell division cycle associated 3

chr2_+_164769892 102.453 ENSMUST00000088248.6
ENSMUST00000001439.6
Ube2c

ubiquitin-conjugating enzyme E2C

chr3_-_8667033 86.903 ENSMUST00000042412.3
Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr10_-_69352886 84.859 ENSMUST00000119827.1
ENSMUST00000020099.5
Cdk1

cyclin-dependent kinase 1

chr9_-_70421533 84.006 ENSMUST00000034742.6
Ccnb2
cyclin B2
chr11_-_102925086 79.277 ENSMUST00000021311.9
Kif18b
kinesin family member 18B
chr13_+_51645232 77.965 ENSMUST00000075853.5
Cks2
CDC28 protein kinase regulatory subunit 2
chr2_-_127831817 77.376 ENSMUST00000028858.7
Bub1
budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
chr2_+_119618717 77.260 ENSMUST00000028771.7
Nusap1
nucleolar and spindle associated protein 1
chr2_-_172370506 74.919 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr7_-_48881596 74.814 ENSMUST00000119223.1
E2f8
E2F transcription factor 8
chr11_+_69045640 74.551 ENSMUST00000108666.1
ENSMUST00000021277.5
Aurkb

aurora kinase B

chr16_+_14163275 72.483 ENSMUST00000023359.6
ENSMUST00000117958.1
Nde1

nuclear distribution gene E homolog 1 (A nidulans)

chr1_+_191821444 70.865 ENSMUST00000027931.7
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr16_+_14163316 70.651 ENSMUST00000115795.2
Nde1
nuclear distribution gene E homolog 1 (A nidulans)
chr17_-_24251382 69.044 ENSMUST00000115390.3
Ccnf
cyclin F
chr9_+_83834684 68.928 ENSMUST00000070326.7
Ttk
Ttk protein kinase
chr16_-_46010212 68.197 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chrX_+_58030622 67.870 ENSMUST00000088627.4
Zic3
zinc finger protein of the cerebellum 3
chr5_+_30666886 67.221 ENSMUST00000144742.1
Cenpa
centromere protein A
chr4_+_115000156 66.876 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr9_+_65890237 66.642 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr4_-_118437331 66.038 ENSMUST00000006565.6
Cdc20
cell division cycle 20
chr5_+_33658567 65.016 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chr4_-_124936852 64.606 ENSMUST00000030690.5
ENSMUST00000084296.3
Cdca8

cell division cycle associated 8

chr5_+_33658123 64.434 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr14_+_55618023 64.358 ENSMUST00000002395.7
Rec8
REC8 homolog (yeast)
chr11_+_95337012 63.211 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr1_-_189688074 61.914 ENSMUST00000171929.1
ENSMUST00000165962.1
Cenpf

centromere protein F

chr3_-_89418287 61.874 ENSMUST00000029679.3
Cks1b
CDC28 protein kinase 1b
chr5_+_115845229 61.398 ENSMUST00000137952.1
ENSMUST00000148245.1
Cit

citron

chr2_-_69206146 61.183 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chr13_-_23745511 59.761 ENSMUST00000091752.2
Hist1h3c
histone cluster 1, H3c
chr6_-_86669136 59.583 ENSMUST00000001184.7
Mxd1
MAX dimerization protein 1
chr2_+_152847961 59.464 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
Tpx2


TPX2, microtubule-associated protein homolog (Xenopus laevis)


chr2_+_25372315 58.918 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr18_-_34751502 58.683 ENSMUST00000060710.7
Cdc25c
cell division cycle 25C
chr13_-_56252163 58.439 ENSMUST00000058475.4
Neurog1
neurogenin 1
chr17_-_35516780 57.175 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
Tcf19


transcription factor 19


chr11_+_72042455 56.938 ENSMUST00000021164.3
Fam64a
family with sequence similarity 64, member A
chr3_+_105704599 56.834 ENSMUST00000066610.7
Fam212b
family with sequence similarity 212, member B
chr4_+_115000174 56.789 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chr5_+_33658550 56.194 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr2_+_152847993 56.081 ENSMUST00000028969.8
Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr2_-_69206133 55.624 ENSMUST00000112320.1
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr13_-_24761861 55.599 ENSMUST00000006898.3
ENSMUST00000110382.2
Gmnn

geminin

chr17_+_56304313 54.813 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
Uhrf1


ubiquitin-like, containing PHD and RING finger domains, 1


chr7_+_79660196 54.046 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr13_-_24761440 53.904 ENSMUST00000176890.1
ENSMUST00000175689.1
Gmnn

geminin

chr5_+_110839973 52.858 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr7_-_48881032 52.732 ENSMUST00000058745.8
E2f8
E2F transcription factor 8
chr14_+_67716095 52.202 ENSMUST00000078053.6
ENSMUST00000145542.1
ENSMUST00000125212.1
Kctd9


potassium channel tetramerisation domain containing 9


chr1_+_131527901 51.992 ENSMUST00000068613.4
Fam72a
family with sequence similarity 72, member A
chr15_-_91191733 51.929 ENSMUST00000069511.6
Abcd2
ATP-binding cassette, sub-family D (ALD), member 2
chr10_+_79997463 51.207 ENSMUST00000171637.1
ENSMUST00000043866.7
Abca7

ATP-binding cassette, sub-family A (ABC1), member 7

chr10_-_81350305 50.762 ENSMUST00000167481.1
Hmg20b
high mobility group 20B
chr7_-_4752972 50.684 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr14_-_65833963 50.081 ENSMUST00000022613.9
Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr12_-_99883429 49.665 ENSMUST00000046485.3
Efcab11
EF-hand calcium binding domain 11
chr11_-_40733373 49.504 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr16_-_17125106 49.381 ENSMUST00000093336.6
2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr2_+_34772089 48.959 ENSMUST00000028222.6
ENSMUST00000100171.2
Hspa5

heat shock protein 5

chr14_+_13284774 48.794 ENSMUST00000070323.5
Synpr
synaptoporin
chr2_-_129297205 48.602 ENSMUST00000052708.6
Ckap2l
cytoskeleton associated protein 2-like
chr3_+_32708546 48.522 ENSMUST00000029214.7
Actl6a
actin-like 6A
chr18_-_61707583 47.419 ENSMUST00000025472.1
Pcyox1l
prenylcysteine oxidase 1 like
chr17_-_56830916 47.002 ENSMUST00000002444.7
ENSMUST00000086801.5
Rfx2

regulatory factor X, 2 (influences HLA class II expression)

chr7_-_135716374 46.675 ENSMUST00000033310.7
Mki67
antigen identified by monoclonal antibody Ki 67
chr11_+_87109221 46.041 ENSMUST00000020794.5
Ska2
spindle and kinetochore associated complex subunit 2
chr4_+_109978004 46.031 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr9_-_121277160 46.023 ENSMUST00000051479.6
ENSMUST00000171923.1
Ulk4

unc-51-like kinase 4

chr19_-_9899450 45.732 ENSMUST00000025562.7
Incenp
inner centromere protein
chr10_-_81350389 44.391 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b



high mobility group 20B



chr9_+_14276301 44.362 ENSMUST00000034507.7
Sesn3
sestrin 3
chr1_+_184034381 44.214 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10
chr11_-_86993682 44.034 ENSMUST00000018571.4
Ypel2
yippee-like 2 (Drosophila)
chr17_-_33890584 44.023 ENSMUST00000114361.2
ENSMUST00000173492.1
Kifc1

kinesin family member C1

chrX_+_58030999 43.752 ENSMUST00000088631.4
ENSMUST00000088629.3
Zic3

zinc finger protein of the cerebellum 3

chr5_-_106458440 43.748 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr7_+_122159422 43.688 ENSMUST00000033154.6
Plk1
polo-like kinase 1
chr1_-_138619687 43.345 ENSMUST00000027642.2
Nek7
NIMA (never in mitosis gene a)-related expressed kinase 7
chr13_+_104229366 43.316 ENSMUST00000022227.6
Cenpk
centromere protein K
chr18_+_34625009 43.177 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr1_+_132316112 43.132 ENSMUST00000082125.5
ENSMUST00000072177.7
Nuak2

NUAK family, SNF1-like kinase, 2

chr13_-_100786402 43.080 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
Ccnb1


cyclin B1


chr9_+_65587187 43.016 ENSMUST00000047099.5
ENSMUST00000131483.1
ENSMUST00000141046.1
Pif1


PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)


chr2_+_181763315 42.657 ENSMUST00000081125.4
Myt1
myelin transcription factor 1
chr19_+_37376359 42.399 ENSMUST00000012587.3
Kif11
kinesin family member 11
chr2_-_154569720 42.049 ENSMUST00000000894.5
E2f1
E2F transcription factor 1
chr17_+_43667389 41.514 ENSMUST00000170988.1
Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr10_-_81350191 41.427 ENSMUST00000122993.1
Hmg20b
high mobility group 20B
chr7_-_120982260 40.833 ENSMUST00000033169.8
Cdr2
cerebellar degeneration-related 2
chr1_+_57995971 40.065 ENSMUST00000027202.8
Sgol2
shugoshin-like 2 (S. pombe)
chr17_-_33890539 39.875 ENSMUST00000173386.1
Kifc1
kinesin family member C1
chr6_-_67037399 39.451 ENSMUST00000043098.6
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr9_+_65587149 39.043 ENSMUST00000134538.1
ENSMUST00000136205.1
Pif1

PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)

chr9_-_91365778 38.653 ENSMUST00000065360.3
Zic1
zinc finger protein of the cerebellum 1
chr2_-_154569845 38.428 ENSMUST00000103145.4
E2f1
E2F transcription factor 1
chr10_-_89443888 38.403 ENSMUST00000099374.2
ENSMUST00000105298.1
Gas2l3

growth arrest-specific 2 like 3

chr7_+_27486910 38.171 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr13_+_104228929 38.005 ENSMUST00000070761.3
Cenpk
centromere protein K
chr3_-_36571952 37.699 ENSMUST00000029270.3
Ccna2
cyclin A2
chr6_-_83121385 37.431 ENSMUST00000146328.1
ENSMUST00000113936.3
ENSMUST00000032111.4
Wbp1


WW domain binding protein 1


chr6_-_54593139 37.387 ENSMUST00000046520.6
Fkbp14
FK506 binding protein 14
chr7_-_30280335 36.875 ENSMUST00000108190.1
Wdr62
WD repeat domain 62
chr6_+_134929089 36.656 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr6_+_128362919 36.597 ENSMUST00000073316.6
Foxm1
forkhead box M1
chr2_+_35132194 36.412 ENSMUST00000113034.1
ENSMUST00000113037.3
ENSMUST00000113033.2
Cep110


centrosomal protein 110


chr13_+_51846673 36.224 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr2_+_158768083 36.175 ENSMUST00000029183.2
Fam83d
family with sequence similarity 83, member D
chr9_-_91365756 35.321 ENSMUST00000034927.6
Zic1
zinc finger protein of the cerebellum 1
chr18_+_34624621 35.255 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr19_-_30175414 34.847 ENSMUST00000025778.7
Gldc
glycine decarboxylase
chr2_-_127133909 34.824 ENSMUST00000110387.3
Ncaph
non-SMC condensin I complex, subunit H
chr13_-_64153194 34.501 ENSMUST00000059817.4
ENSMUST00000117241.1
Zfp367

zinc finger protein 367

chr6_+_134929118 34.436 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr11_+_102604370 34.155 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr15_+_85859689 34.022 ENSMUST00000170629.1
Gtse1
G two S phase expressed protein 1
chr2_-_119618455 33.710 ENSMUST00000123818.1
Oip5
Opa interacting protein 5
chr4_-_41464816 33.206 ENSMUST00000108055.2
ENSMUST00000154535.1
ENSMUST00000030148.5
Kif24


kinesin family member 24


chr14_+_67716262 33.144 ENSMUST00000150768.1
Kctd9
potassium channel tetramerisation domain containing 9
chr11_-_6444352 33.127 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr7_+_45434833 32.812 ENSMUST00000003964.8
Gys1
glycogen synthase 1, muscle
chr1_+_134962553 32.565 ENSMUST00000027687.7
Ube2t
ubiquitin-conjugating enzyme E2T (putative)
chr3_+_135212557 32.495 ENSMUST00000062893.7
Cenpe
centromere protein E
chr7_+_4740178 32.455 ENSMUST00000108583.2
Suv420h2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr13_+_108316332 32.422 ENSMUST00000051594.5
Depdc1b
DEP domain containing 1B
chr10_+_94036001 32.150 ENSMUST00000020208.4
Fgd6
FYVE, RhoGEF and PH domain containing 6
chr7_+_45434876 31.992 ENSMUST00000107766.1
Gys1
glycogen synthase 1, muscle
chr11_+_44617310 31.970 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr16_-_18811615 31.631 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr7_-_127042420 31.533 ENSMUST00000032915.6
Kif22
kinesin family member 22
chr5_+_136084022 31.459 ENSMUST00000100570.3
Rasa4
RAS p21 protein activator 4
chr17_-_25727364 31.088 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr4_-_132510493 30.653 ENSMUST00000030724.8
Sesn2
sestrin 2
chr11_-_106999482 30.382 ENSMUST00000018506.6
Kpna2
karyopherin (importin) alpha 2
chr5_-_114690974 30.342 ENSMUST00000012028.7
Gltp
glycolipid transfer protein
chr7_+_4740111 30.331 ENSMUST00000098853.2
Suv420h2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr7_+_4740137 30.317 ENSMUST00000130215.1
ENSMUST00000108582.3
Suv420h2

suppressor of variegation 4-20 homolog 2 (Drosophila)

chr12_-_111813834 30.270 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr5_+_136083916 30.110 ENSMUST00000042135.7
Rasa4
RAS p21 protein activator 4
chr16_-_10543028 29.933 ENSMUST00000184863.1
ENSMUST00000038281.5
Dexi

dexamethasone-induced transcript

chrX_+_100625737 29.758 ENSMUST00000048962.3
Kif4
kinesin family member 4
chr5_+_123749696 29.740 ENSMUST00000031366.7
Kntc1
kinetochore associated 1
chr15_+_102296256 29.630 ENSMUST00000064924.4
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr11_-_106999369 29.630 ENSMUST00000106768.1
ENSMUST00000144834.1
Kpna2

karyopherin (importin) alpha 2

chr11_-_101551837 29.622 ENSMUST00000017290.4
Brca1
breast cancer 1
chr17_+_56303321 29.588 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr14_+_55824795 29.265 ENSMUST00000024179.5
ENSMUST00000172271.1
Nfatc4

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4

chr8_+_87473116 29.112 ENSMUST00000182650.1
ENSMUST00000182758.1
ENSMUST00000181898.1
Gm2694


predicted gene 2694


chr11_-_100939357 29.045 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr14_+_99046406 29.004 ENSMUST00000022656.6
Bora
bora, aurora kinase A activator
chr15_-_99651580 28.935 ENSMUST00000171908.1
ENSMUST00000171702.1
ENSMUST00000109581.2
ENSMUST00000169810.1
ENSMUST00000023756.5
Racgap1




Rac GTPase-activating protein 1




chr14_-_8666236 28.861 ENSMUST00000102996.3
4930452B06Rik
RIKEN cDNA 4930452B06 gene
chr3_+_89418443 28.842 ENSMUST00000039110.5
ENSMUST00000125036.1
ENSMUST00000154791.1
ENSMUST00000128238.1
ENSMUST00000107417.2
Shc1




src homology 2 domain-containing transforming protein C1




chr5_+_144545883 28.816 ENSMUST00000071782.6
Nptx2
neuronal pentraxin 2
chr5_+_137629112 28.349 ENSMUST00000031734.9
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr2_+_118861954 28.330 ENSMUST00000028807.5
Ivd
isovaleryl coenzyme A dehydrogenase
chr9_+_96196246 28.207 ENSMUST00000165120.2
ENSMUST00000034982.9
Tfdp2

transcription factor Dp 2

chr10_-_85127977 28.147 ENSMUST00000050813.2
Mterfd3
MTERF domain containing 3
chr11_-_100939540 28.120 ENSMUST00000127638.1
Stat3
signal transducer and activator of transcription 3
chr11_-_84525514 28.120 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr4_+_136172367 27.813 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr2_+_105668888 27.771 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr11_-_100939457 27.740 ENSMUST00000138438.1
Stat3
signal transducer and activator of transcription 3
chr17_+_56303396 27.645 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr3_+_108383829 27.585 ENSMUST00000090561.3
ENSMUST00000102629.1
ENSMUST00000128089.1
Psrc1


proline/serine-rich coiled-coil 1


chr5_+_92809372 27.438 ENSMUST00000113054.2
Shroom3
shroom family member 3
chr4_-_135873801 27.359 ENSMUST00000030436.5
Pnrc2
proline-rich nuclear receptor coactivator 2
chr17_+_26917091 27.306 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chr13_-_23762378 27.177 ENSMUST00000091701.2
Hist1h3a
histone cluster 1, H3a
chr19_-_46044914 27.048 ENSMUST00000026252.7
Ldb1
LIM domain binding 1
chr12_-_83921899 27.029 ENSMUST00000117217.1
Numb
numb gene homolog (Drosophila)
chr8_-_22185758 26.945 ENSMUST00000046916.7
Ckap2
cytoskeleton associated protein 2
chr16_-_18811972 26.853 ENSMUST00000000028.7
ENSMUST00000115585.1
Cdc45

cell division cycle 45

chr13_+_108316395 26.812 ENSMUST00000171178.1
Depdc1b
DEP domain containing 1B
chr5_+_137629169 26.724 ENSMUST00000176667.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr10_-_88146867 26.706 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp



PARP1 binding protein



chr4_+_11558914 26.320 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
Rad54b



RAD54 homolog B (S. cerevisiae)



chr7_-_35056467 26.052 ENSMUST00000130491.1
Cebpg
CCAAT/enhancer binding protein (C/EBP), gamma
chr11_+_43682038 25.908 ENSMUST00000094294.4
Pwwp2a
PWWP domain containing 2A
chr9_+_72438519 25.893 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr7_-_49636847 25.799 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr11_-_120727226 25.733 ENSMUST00000106148.3
ENSMUST00000026144.4
Dcxr

dicarbonyl L-xylulose reductase

chr1_-_134079114 25.711 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
73.3 220.0 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
45.5 181.8 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
43.3 129.9 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
33.1 198.7 GO:0009786 regulation of asymmetric cell division(GO:0009786)
29.4 529.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
28.0 83.9 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
27.9 55.8 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
26.8 80.5 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
25.0 74.9 GO:0060282 positive regulation of oocyte development(GO:0060282)
24.0 119.8 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
23.4 328.2 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
21.2 84.9 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
21.1 84.4 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
20.0 139.8 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
19.5 58.5 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
18.6 111.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
17.5 17.5 GO:0061303 cornea development in camera-type eye(GO:0061303)
17.3 52.0 GO:0030862 neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862)
16.3 49.0 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
16.3 32.6 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
15.8 47.4 GO:0007290 spermatid nucleus elongation(GO:0007290)
15.8 47.4 GO:0030327 prenylated protein catabolic process(GO:0030327)
15.6 140.8 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
15.3 30.7 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
15.2 45.5 GO:1990705 cholangiocyte proliferation(GO:1990705)
14.6 58.4 GO:0021648 zygotic determination of anterior/posterior axis, embryo(GO:0007354) cranial nerve formation(GO:0021603) vestibulocochlear nerve morphogenesis(GO:0021648)
14.1 28.1 GO:0097477 lateral motor column neuron migration(GO:0097477)
13.7 123.7 GO:0033504 floor plate development(GO:0033504)
13.7 41.0 GO:1903334 positive regulation of protein folding(GO:1903334)
13.4 214.3 GO:0007100 mitotic centrosome separation(GO:0007100)
13.2 52.9 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
12.9 180.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
12.4 49.7 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
12.2 12.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
12.0 36.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
12.0 35.9 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
11.7 82.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
11.6 34.8 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
11.4 56.9 GO:2000427 apolipoprotein A-I-mediated signaling pathway(GO:0038027) positive regulation of apoptotic cell clearance(GO:2000427)
11.3 79.4 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
10.1 10.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
10.0 30.1 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
10.0 311.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
10.0 50.1 GO:0034421 post-translational protein acetylation(GO:0034421)
10.0 29.9 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
9.8 19.6 GO:0035622 intrahepatic bile duct development(GO:0035622)
9.8 29.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
9.7 48.5 GO:0060022 hard palate development(GO:0060022)
9.6 95.6 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
9.4 28.2 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
8.8 26.4 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
8.6 112.0 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
8.6 25.7 GO:0042732 D-xylose metabolic process(GO:0042732)
8.5 51.2 GO:0051255 spindle midzone assembly(GO:0051255)
8.5 67.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
8.2 24.5 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
7.9 15.9 GO:0090365 regulation of mRNA modification(GO:0090365)
7.7 46.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
7.5 217.6 GO:0051310 metaphase plate congression(GO:0051310)
7.4 36.8 GO:1990839 response to endothelin(GO:1990839)
7.3 7.3 GO:0060364 frontal suture morphogenesis(GO:0060364)
7.3 102.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
7.3 123.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
7.2 172.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
7.1 78.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
7.0 28.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
6.9 62.3 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
6.9 27.4 GO:0061198 fungiform papilla formation(GO:0061198)
6.8 20.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
6.8 20.5 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
6.8 27.0 GO:0043973 histone H3-K4 acetylation(GO:0043973)
6.7 20.2 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
6.7 13.5 GO:0002645 positive regulation of tolerance induction(GO:0002645)
6.7 13.4 GO:0010847 regulation of chromatin assembly(GO:0010847)
6.5 52.0 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
6.5 6.5 GO:0097374 sensory neuron axon guidance(GO:0097374)
6.5 12.9 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
6.2 18.6 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
6.1 18.3 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
6.1 54.7 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
6.0 24.2 GO:0070459 prolactin secretion(GO:0070459)
6.0 23.8 GO:0034239 regulation of macrophage fusion(GO:0034239)
5.9 17.7 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
5.8 11.6 GO:0007096 regulation of exit from mitosis(GO:0007096)
5.8 51.9 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
5.7 17.1 GO:0021759 globus pallidus development(GO:0021759)
5.7 17.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
5.6 33.7 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
5.6 27.8 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
5.4 48.8 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
5.4 32.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
5.3 10.7 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
5.3 15.8 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
5.3 31.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
5.1 5.1 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
5.1 20.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
5.0 24.9 GO:0048478 replication fork protection(GO:0048478)
5.0 59.5 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
4.9 24.7 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
4.9 44.4 GO:0038203 TORC2 signaling(GO:0038203)
4.9 73.7 GO:0048194 Golgi vesicle budding(GO:0048194)
4.7 18.9 GO:0006272 leading strand elongation(GO:0006272)
4.6 9.2 GO:0030222 eosinophil differentiation(GO:0030222)
4.6 32.1 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
4.5 13.6 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
4.5 22.4 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
4.4 31.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
4.4 39.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
4.4 13.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
4.3 12.9 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
4.2 29.7 GO:0072615 interleukin-17 secretion(GO:0072615)
4.2 8.4 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
4.2 21.0 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
4.2 12.5 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
4.1 12.4 GO:0006285 base-excision repair, AP site formation(GO:0006285)
4.1 45.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
4.1 8.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
4.1 20.5 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
4.1 12.2 GO:0034508 centromere complex assembly(GO:0034508)
4.0 28.3 GO:0006551 leucine metabolic process(GO:0006551)
4.0 44.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
4.0 56.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
4.0 16.1 GO:0002035 brain renin-angiotensin system(GO:0002035)
4.0 64.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
4.0 12.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
4.0 15.9 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
3.9 7.8 GO:0051026 chiasma assembly(GO:0051026)
3.9 15.7 GO:0072344 rescue of stalled ribosome(GO:0072344)
3.9 54.6 GO:0043486 histone exchange(GO:0043486)
3.9 42.7 GO:0060539 diaphragm development(GO:0060539)
3.9 15.4 GO:0000733 DNA strand renaturation(GO:0000733)
3.9 3.9 GO:0007386 compartment pattern specification(GO:0007386)
3.8 95.9 GO:0006270 DNA replication initiation(GO:0006270)
3.8 11.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
3.8 3.8 GO:0051299 centrosome separation(GO:0051299)
3.8 15.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
3.7 22.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
3.7 11.0 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
3.6 3.6 GO:0046686 response to cadmium ion(GO:0046686)
3.6 21.5 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
3.5 10.6 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
3.5 42.5 GO:0002227 innate immune response in mucosa(GO:0002227)
3.5 7.1 GO:0033566 gamma-tubulin complex localization(GO:0033566)
3.5 63.0 GO:0044458 motile cilium assembly(GO:0044458)
3.5 14.0 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
3.5 10.4 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
3.5 24.4 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
3.5 45.1 GO:0036297 interstrand cross-link repair(GO:0036297)
3.4 27.4 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
3.4 65.1 GO:0007099 centriole replication(GO:0007099)
3.4 27.3 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
3.4 10.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
3.4 16.9 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
3.4 43.9 GO:0001675 acrosome assembly(GO:0001675)
3.4 10.1 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819) negative regulation of apoptotic cell clearance(GO:2000426)
3.4 40.4 GO:0071850 mitotic cell cycle arrest(GO:0071850)
3.3 10.0 GO:1903984 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
3.3 29.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
3.3 56.1 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
3.3 46.1 GO:0070986 left/right axis specification(GO:0070986)
3.3 6.5 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
3.3 13.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
3.3 6.5 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
3.3 35.8 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
3.2 9.7 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
3.2 9.6 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
3.2 6.3 GO:1904251 regulation of bile acid metabolic process(GO:1904251)
3.2 9.5 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
3.1 12.6 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
3.1 144.6 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
3.1 43.9 GO:0043968 histone H2A acetylation(GO:0043968)
3.1 9.4 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
3.1 15.5 GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
3.1 24.7 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
3.1 36.9 GO:0051307 meiotic chromosome separation(GO:0051307)
3.1 15.4 GO:0071896 protein localization to adherens junction(GO:0071896)
3.1 24.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
3.1 6.1 GO:0061314 Notch signaling involved in heart development(GO:0061314)
3.0 21.3 GO:0048102 autophagic cell death(GO:0048102)
3.0 15.2 GO:1903232 melanosome assembly(GO:1903232)
3.0 6.0 GO:0006172 ADP biosynthetic process(GO:0006172)
3.0 144.1 GO:0008156 negative regulation of DNA replication(GO:0008156)
3.0 17.9 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
2.9 253.0 GO:0006342 chromatin silencing(GO:0006342)
2.9 11.5 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
2.9 5.8 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
2.8 8.5 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
2.8 5.6 GO:0061525 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
2.8 16.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
2.8 16.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
2.7 5.5 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
2.7 13.7 GO:0090383 phagosome acidification(GO:0090383)
2.7 13.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
2.7 413.3 GO:0007059 chromosome segregation(GO:0007059)
2.6 7.8 GO:0032474 otolith morphogenesis(GO:0032474)
2.6 10.3 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
2.5 7.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
2.5 27.8 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
2.5 4.9 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
2.5 7.4 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
2.5 14.8 GO:0034587 piRNA metabolic process(GO:0034587)
2.4 9.8 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
2.4 7.3 GO:0006533 aspartate catabolic process(GO:0006533)
2.4 131.0 GO:0006334 nucleosome assembly(GO:0006334)
2.4 2.4 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
2.4 16.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
2.4 62.4 GO:0001709 cell fate determination(GO:0001709)
2.4 2.4 GO:1904431 positive regulation of t-circle formation(GO:1904431)
2.4 66.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
2.4 7.1 GO:0060290 transdifferentiation(GO:0060290)
2.4 4.7 GO:0048496 maintenance of organ identity(GO:0048496)
2.3 7.0 GO:0019323 pentose catabolic process(GO:0019323)
2.3 97.8 GO:0048538 thymus development(GO:0048538)
2.3 6.9 GO:0070375 ERK5 cascade(GO:0070375)
2.3 25.3 GO:0006699 bile acid biosynthetic process(GO:0006699)
2.3 13.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
2.3 9.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
2.3 4.5 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
2.3 6.8 GO:0021747 cochlear nucleus development(GO:0021747)
2.2 6.7 GO:1900034 regulation of cellular response to heat(GO:1900034)
2.2 18.0 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
2.2 15.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
2.2 26.6 GO:0033327 Leydig cell differentiation(GO:0033327)
2.2 64.1 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
2.2 6.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
2.2 6.6 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
2.2 30.6 GO:0030320 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320)
2.2 32.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
2.2 8.6 GO:0003415 chondrocyte hypertrophy(GO:0003415)
2.1 2.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
2.1 14.9 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
2.1 6.3 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
2.1 16.8 GO:0072189 ureter development(GO:0072189)
2.1 2.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
2.1 10.4 GO:0006868 glutamine transport(GO:0006868)
2.1 2.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
2.1 2.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
2.1 10.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
2.1 10.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
2.0 8.2 GO:0031297 replication fork processing(GO:0031297) DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
2.0 26.6 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
2.0 8.1 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
2.0 56.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
2.0 4.0 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
2.0 14.0 GO:0030035 microspike assembly(GO:0030035)
2.0 35.9 GO:1904355 positive regulation of telomere capping(GO:1904355)
2.0 8.0 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
2.0 21.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
1.9 5.8 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
1.9 15.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
1.9 5.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
1.9 5.6 GO:0042637 catagen(GO:0042637)
1.8 31.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.8 3.7 GO:0031058 positive regulation of histone modification(GO:0031058) positive regulation of chromatin modification(GO:1903310)
1.8 7.3 GO:0060325 head morphogenesis(GO:0060323) face morphogenesis(GO:0060325)
1.8 3.7 GO:0050904 diapedesis(GO:0050904)
1.8 7.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
1.8 27.1 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
1.8 7.2 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
1.8 25.0 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
1.8 41.0 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
1.8 3.6 GO:0010040 response to iron(II) ion(GO:0010040)
1.8 184.5 GO:0007050 cell cycle arrest(GO:0007050)
1.8 16.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
1.8 15.9 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
1.8 3.5 GO:0046110 xanthine metabolic process(GO:0046110)
1.8 8.8 GO:0035405 histone-threonine phosphorylation(GO:0035405)
1.7 3.4 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
1.6 9.8 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
1.6 3.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
1.6 4.7 GO:0070650 actin filament bundle distribution(GO:0070650)
1.6 9.3 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
1.5 1.5 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
1.5 1.5 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
1.5 4.5 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
1.5 7.4 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
1.5 4.4 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
1.5 1.5 GO:2000277 regulation of oxidative phosphorylation uncoupler activity(GO:2000275) positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
1.5 29.1 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
1.5 4.4 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
1.5 1.5 GO:0003162 atrioventricular node development(GO:0003162)
1.4 1.4 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
1.4 4.3 GO:0035372 protein localization to microtubule(GO:0035372)
1.4 4.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.4 8.6 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
1.4 1.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
1.4 7.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
1.4 18.4 GO:0015780 nucleotide-sugar transport(GO:0015780)
1.4 15.5 GO:0060009 Sertoli cell development(GO:0060009)
1.4 8.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
1.4 15.4 GO:0070836 caveola assembly(GO:0070836)
1.4 13.9 GO:0021511 spinal cord patterning(GO:0021511)
1.4 4.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
1.4 1.4 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
1.4 1.4 GO:0032875 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
1.4 8.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
1.4 5.4 GO:0015888 thiamine transport(GO:0015888)
1.4 1.4 GO:0051660 establishment of centrosome localization(GO:0051660)
1.3 1.3 GO:0044805 late nucleophagy(GO:0044805)
1.3 4.0 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
1.3 5.4 GO:0006776 vitamin A metabolic process(GO:0006776) positive regulation of skeletal muscle tissue regeneration(GO:0043415)
1.3 14.7 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
1.3 13.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
1.3 6.6 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
1.3 11.7 GO:0097237 cellular response to toxic substance(GO:0097237)
1.3 3.9 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
1.3 5.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.3 12.9 GO:0051451 myoblast migration(GO:0051451)
1.3 3.8 GO:0071579 regulation of zinc ion transport(GO:0071579)
1.3 5.1 GO:0060056 mammary gland involution(GO:0060056)
1.3 3.8 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.3 2.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
1.3 8.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
1.3 11.3 GO:0006817 phosphate ion transport(GO:0006817)
1.3 11.3 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
1.2 16.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
1.2 9.9 GO:1902416 positive regulation of mRNA binding(GO:1902416)
1.2 3.7 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
1.2 7.4 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
1.2 3.7 GO:0035672 transepithelial chloride transport(GO:0030321) oligopeptide transmembrane transport(GO:0035672)
1.2 3.7 GO:0001928 regulation of exocyst assembly(GO:0001928)
1.2 11.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
1.2 6.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
1.2 3.6 GO:0030043 actin filament fragmentation(GO:0030043)
1.2 4.8 GO:0030091 protein repair(GO:0030091)
1.2 3.5 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
1.2 15.3 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
1.1 6.9 GO:0060192 negative regulation of lipase activity(GO:0060192)
1.1 52.2 GO:0007628 adult walking behavior(GO:0007628)
1.1 4.5 GO:0040016 embryonic cleavage(GO:0040016)
1.1 33.9 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
1.1 9.0 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
1.1 2.3 GO:0014029 neural crest formation(GO:0014029)
1.1 4.5 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636) negative regulation of mitochondrial fission(GO:0090258)
1.1 23.5 GO:0045116 protein neddylation(GO:0045116)
1.1 21.9 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of hemostasis(GO:1900048)
1.1 2.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.1 3.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
1.0 7.3 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
1.0 11.4 GO:0043249 erythrocyte maturation(GO:0043249)
1.0 2.1 GO:1902022 L-lysine transport(GO:1902022)
1.0 10.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
1.0 16.3 GO:0006301 postreplication repair(GO:0006301)
1.0 14.2 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
1.0 2.0 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
1.0 11.1 GO:2000035 regulation of stem cell division(GO:2000035)
1.0 3.0 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.0 6.8 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
1.0 2.9 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
1.0 7.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.9 10.3 GO:0060736 prostate gland growth(GO:0060736)
0.9 4.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.9 1.9 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.9 13.9 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.9 9.2 GO:0009409 response to cold(GO:0009409)
0.9 82.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.9 17.5 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.9 2.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.9 3.6 GO:0071305 cellular response to vitamin D(GO:0071305)
0.9 0.9 GO:0022616 DNA strand elongation(GO:0022616)
0.9 1.8 GO:0072719 cellular response to cisplatin(GO:0072719)
0.9 0.9 GO:0006404 RNA import into nucleus(GO:0006404)
0.9 7.1 GO:0090178 regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.9 3.5 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.9 4.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.8 5.1 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.8 22.2 GO:0000281 mitotic cytokinesis(GO:0000281)
0.8 4.9 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.8 3.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.8 4.0 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.8 3.2 GO:0072592 oxygen metabolic process(GO:0072592) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.8 6.4 GO:0016139 glycoside catabolic process(GO:0016139)
0.8 6.3 GO:1900364 regulation of mRNA polyadenylation(GO:1900363) negative regulation of mRNA polyadenylation(GO:1900364)
0.8 7.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.8 11.7 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.8 3.1 GO:0002339 B cell selection(GO:0002339)
0.8 4.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.8 2.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.8 9.8 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.8 1.5 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.7 1.5 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.7 6.6 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.7 2.9 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.7 5.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.7 7.9 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.7 2.2 GO:0044030 regulation of DNA methylation(GO:0044030)
0.7 1.4 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.7 2.1 GO:0072172 ureteric bud formation(GO:0060676) mesonephric tubule formation(GO:0072172)
0.7 7.8 GO:0006972 hyperosmotic response(GO:0006972)
0.7 4.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.7 2.1 GO:0042126 nitrate metabolic process(GO:0042126)
0.7 6.9 GO:0080009 mRNA methylation(GO:0080009)
0.7 6.1 GO:0061436 establishment of skin barrier(GO:0061436)
0.7 6.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.7 8.5 GO:0043277 apoptotic cell clearance(GO:0043277)
0.7 3.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.6 4.5 GO:2000811 negative regulation of anoikis(GO:2000811)
0.6 3.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.6 1.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.6 2.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.6 13.7 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.6 1.2 GO:0032202 telomere assembly(GO:0032202)
0.6 0.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.6 1.8 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.6 3.0 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.6 6.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.6 2.3 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.6 5.8 GO:0018065 protein-cofactor linkage(GO:0018065)
0.6 7.6 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.6 3.5 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.6 5.8 GO:0001947 heart looping(GO:0001947)
0.6 12.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.6 3.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.6 2.8 GO:0051567 histone H3-K9 methylation(GO:0051567)
0.6 10.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.6 5.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.6 3.4 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.6 9.0 GO:0042438 melanin biosynthetic process(GO:0042438)
0.6 2.2 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.6 1.1 GO:0097168 mesenchymal stem cell maintenance involved in nephron morphogenesis(GO:0072038) mesenchymal stem cell proliferation(GO:0097168)
0.5 2.2 GO:0061743 motor learning(GO:0061743)
0.5 12.6 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.5 6.0 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.5 16.7 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.5 5.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.5 1.1 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.5 23.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.5 3.6 GO:0002377 immunoglobulin production(GO:0002377)
0.5 5.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.5 5.2 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.5 3.5 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.5 1.0 GO:0009838 abscission(GO:0009838)
0.5 3.5 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.5 3.9 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.5 13.8 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.5 11.8 GO:0006284 base-excision repair(GO:0006284)
0.5 6.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.5 0.5 GO:1902591 single-organism membrane budding(GO:1902591)
0.5 10.6 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.5 3.4 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.5 5.3 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.5 8.0 GO:0048854 brain morphogenesis(GO:0048854)
0.5 0.9 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.5 28.8 GO:0001843 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.5 5.4 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.4 0.9 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.4 9.3 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.4 7.0 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.4 6.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.4 3.9 GO:0000303 response to superoxide(GO:0000303) adaptive thermogenesis(GO:1990845)
0.4 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.4 2.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.4 7.6 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.4 7.9 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.4 4.5 GO:0048536 spleen development(GO:0048536)
0.4 1.2 GO:0009068 aspartate family amino acid catabolic process(GO:0009068)
0.4 4.1 GO:0006691 leukotriene metabolic process(GO:0006691)
0.4 3.7 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.4 8.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.4 0.8 GO:2000780 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.4 3.3 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.4 5.3 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.4 12.4 GO:0060425 lung morphogenesis(GO:0060425)
0.4 2.0 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.4 8.3 GO:0009880 embryonic pattern specification(GO:0009880)
0.4 8.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.4 3.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.4 1.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.4 10.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.4 4.6 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.4 1.9 GO:0071361 cellular response to ethanol(GO:0071361)
0.4 4.6 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.4 0.8 GO:1902302 regulation of potassium ion export(GO:1902302)
0.4 5.2 GO:0016574 histone ubiquitination(GO:0016574)
0.4 2.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.4 1.1 GO:0045639 positive regulation of myeloid cell differentiation(GO:0045639)
0.4 1.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.4 0.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.4 5.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.4 9.3 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.4 6.1 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.4 5.7 GO:0036293 response to hypoxia(GO:0001666) response to decreased oxygen levels(GO:0036293)
0.3 2.1 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.3 3.8 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.3 8.4 GO:0045047 protein targeting to ER(GO:0045047)
0.3 14.9 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.3 1.7 GO:0051697 protein delipidation(GO:0051697)
0.3 5.5 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.3 1.3 GO:0051409 response to nitrosative stress(GO:0051409)
0.3 12.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.3 10.3 GO:0016925 protein sumoylation(GO:0016925)
0.3 1.3 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.3 10.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.3 0.7 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.3 5.2 GO:0044243 multicellular organism catabolic process(GO:0044243)
0.3 2.3 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.3 19.7 GO:0000187 activation of MAPK activity(GO:0000187)
0.3 9.3 GO:0046039 GTP metabolic process(GO:0046039)
0.3 0.3 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967) negative regulation of gene silencing(GO:0060969)
0.3 1.3 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.3 1.9 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.3 1.9 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.3 5.4 GO:0009065 glutamine family amino acid catabolic process(GO:0009065)
0.3 1.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.3 1.9 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.3 1.9 GO:0060438 trachea development(GO:0060438)
0.3 7.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.3 0.9 GO:0032375 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.3 1.2 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.3 0.3 GO:0009106 lipoate metabolic process(GO:0009106)
0.3 2.9 GO:0001841 neural tube formation(GO:0001841)
0.3 6.7 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.3 0.9 GO:0044068 modulation by symbiont of host cellular process(GO:0044068)
0.3 14.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.3 3.7 GO:0043248 proteasome assembly(GO:0043248)
0.3 3.1 GO:0014823 response to activity(GO:0014823)
0.3 1.4 GO:0090527 actin filament reorganization(GO:0090527)
0.3 4.2 GO:0050832 defense response to fungus(GO:0050832)
0.3 0.6 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.3 1.1 GO:0061623 glycolytic process from galactose(GO:0061623)
0.3 8.2 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.3 5.9 GO:0060612 adipose tissue development(GO:0060612)
0.3 4.7 GO:0006801 superoxide metabolic process(GO:0006801)
0.3 2.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.3 0.8 GO:0042823 water-soluble vitamin biosynthetic process(GO:0042364) pyridoxal phosphate biosynthetic process(GO:0042823)
0.3 9.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.3 2.8 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.3 1.0 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 3.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.2 0.5 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.2 1.0 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.2 14.5 GO:0045137 development of primary sexual characteristics(GO:0045137)
0.2 2.1 GO:0030049 muscle filament sliding(GO:0030049)
0.2 4.2 GO:0045214 sarcomere organization(GO:0045214)
0.2 3.0 GO:0021859 pyramidal neuron differentiation(GO:0021859)
0.2 5.3 GO:0010259 multicellular organism aging(GO:0010259)
0.2 0.7 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 1.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 0.9 GO:0035617 positive regulation of synaptic transmission, GABAergic(GO:0032230) stress granule disassembly(GO:0035617)
0.2 2.8 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 1.1 GO:0036337 Fas signaling pathway(GO:0036337)
0.2 2.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 0.6 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 1.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.2 0.8 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.2 1.9 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.2 0.4 GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.2 2.3 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 4.6 GO:0070527 platelet aggregation(GO:0070527)
0.2 0.4 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.2 1.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070)
0.2 4.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 1.4 GO:0031274 regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.2 1.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.2 5.1 GO:0035329 hippo signaling(GO:0035329)
0.2 1.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.2 5.6 GO:0030500 regulation of bone mineralization(GO:0030500)
0.2 0.7 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.2 2.4 GO:0006378 mRNA polyadenylation(GO:0006378)
0.2 1.7 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.2 6.2 GO:0051028 mRNA transport(GO:0051028)
0.2 3.1 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.2 0.5 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.1 0.3 GO:0036490 regulation of translation in response to endoplasmic reticulum stress(GO:0036490)
0.1 1.7 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 0.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.8 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.6 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 4.1 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.1 1.1 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 3.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 1.2 GO:0006298 mismatch repair(GO:0006298)
0.1 2.6 GO:0019835 cytolysis(GO:0019835)
0.1 6.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 2.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.3 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.1 4.5 GO:0060348 bone development(GO:0060348)
0.1 1.3 GO:0003170 heart valve development(GO:0003170)
0.1 2.3 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.3 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.5 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.1 1.0 GO:0015800 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.1 0.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 2.0 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.1 0.6 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 0.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.1 0.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.9 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.8 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 0.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 1.0 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 0.1 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.1 1.2 GO:0014002 astrocyte development(GO:0014002)
0.1 3.2 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.1 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 1.1 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.1 0.5 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 5.0 GO:0000045 autophagosome assembly(GO:0000045)
0.1 0.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 3.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 3.4 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.1 0.7 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.4 GO:0048266 behavioral response to pain(GO:0048266)
0.1 2.2 GO:0000075 cell cycle checkpoint(GO:0000075)
0.1 0.5 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 0.7 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 1.8 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1 1.3 GO:0016575 histone deacetylation(GO:0016575)
0.1 2.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.2 GO:0019585 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) cellular glucuronidation(GO:0052695)
0.1 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.7 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.3 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 1.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.4 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.9 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.4 GO:0019471 4-hydroxyproline metabolic process(GO:0019471)
0.0 1.0 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.3 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 0.3 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.1 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.1 GO:0035646 endosome to melanosome transport(GO:0035646) pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.2 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.4 GO:0051099 positive regulation of binding(GO:0051099)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
82.6 412.9 GO:0097149 centralspindlin complex(GO:0097149)
42.8 214.1 GO:0032133 chromosome passenger complex(GO:0032133)
41.0 164.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
34.1 136.6 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
27.8 194.8 GO:0005818 aster(GO:0005818)
27.1 135.6 GO:0031262 Ndc80 complex(GO:0031262)
25.2 125.9 GO:0036449 microtubule minus-end(GO:0036449)
19.8 59.3 GO:0000799 nuclear condensin complex(GO:0000799)
19.7 196.7 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
19.5 58.5 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
16.1 80.5 GO:0035189 Rb-E2F complex(GO:0035189)
15.4 108.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
15.2 45.7 GO:0000801 central element(GO:0000801)
14.7 250.3 GO:0031616 spindle pole centrosome(GO:0031616)
13.7 13.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
13.0 39.0 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
9.9 29.7 GO:1990423 RZZ complex(GO:1990423)
9.9 128.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
9.3 46.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
7.5 29.9 GO:0035339 SPOTS complex(GO:0035339)
7.1 178.3 GO:0005680 anaphase-promoting complex(GO:0005680)
7.0 7.0 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
6.3 252.6 GO:0005876 spindle microtubule(GO:0005876)
6.2 436.8 GO:0000786 nucleosome(GO:0000786)
6.2 31.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
6.2 74.1 GO:0061700 GATOR2 complex(GO:0061700)
6.0 24.2 GO:0043202 lysosomal lumen(GO:0043202)
5.7 22.6 GO:0043293 apoptosome(GO:0043293)
5.5 87.6 GO:0010369 chromocenter(GO:0010369)
5.4 37.7 GO:0001940 male pronucleus(GO:0001940)
5.3 10.6 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
5.0 30.1 GO:0070531 BRCA1-A complex(GO:0070531)
5.0 5.0 GO:0001739 sex chromatin(GO:0001739)
4.5 13.5 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
4.5 22.3 GO:0031298 replication fork protection complex(GO:0031298)
4.4 17.7 GO:0045098 type III intermediate filament(GO:0045098)
4.4 17.4 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
4.3 455.3 GO:0000793 condensed chromosome(GO:0000793)
4.2 29.7 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
4.2 59.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
4.1 258.8 GO:0005657 replication fork(GO:0005657)
4.0 16.2 GO:0071942 XPC complex(GO:0071942)
4.0 4.0 GO:0042585 germinal vesicle(GO:0042585)
3.9 30.9 GO:0005785 signal recognition particle receptor complex(GO:0005785)
3.7 26.1 GO:0045120 pronucleus(GO:0045120)
3.7 55.8 GO:0031011 Ino80 complex(GO:0031011)
3.7 14.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
3.6 21.5 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
3.5 3.5 GO:0036488 CHOP-C/EBP complex(GO:0036488)
3.5 180.1 GO:0005871 kinesin complex(GO:0005871)
3.4 20.7 GO:0097513 myosin II filament(GO:0097513)
3.4 27.2 GO:0005721 pericentric heterochromatin(GO:0005721)
3.3 83.3 GO:0001891 phagocytic cup(GO:0001891)
3.3 6.6 GO:0001939 female pronucleus(GO:0001939)
3.3 236.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
3.2 16.2 GO:1990037 Lewy body core(GO:1990037)
3.2 9.7 GO:0033186 CAF-1 complex(GO:0033186)
3.2 9.6 GO:0071914 prominosome(GO:0071914)
3.2 9.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
3.1 21.4 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
3.0 301.7 GO:0000776 kinetochore(GO:0000776)
3.0 24.4 GO:0005883 neurofilament(GO:0005883)
2.8 11.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
2.8 41.7 GO:0030061 mitochondrial crista(GO:0030061)
2.7 8.2 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
2.7 13.5 GO:0072687 meiotic spindle(GO:0072687)
2.6 7.9 GO:0031251 PAN complex(GO:0031251)
2.6 28.9 GO:0097431 mitotic spindle pole(GO:0097431)
2.6 23.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
2.6 33.5 GO:0042555 MCM complex(GO:0042555)
2.4 16.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
2.4 11.9 GO:0032437 cuticular plate(GO:0032437)
2.4 7.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
2.3 14.0 GO:0044305 calyx of Held(GO:0044305)
2.3 9.3 GO:0032444 activin responsive factor complex(GO:0032444)
2.3 27.6 GO:0016580 Sin3 complex(GO:0016580)
2.3 6.8 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
2.3 31.8 GO:0030008 TRAPP complex(GO:0030008)
2.3 31.6 GO:0030127 COPII vesicle coat(GO:0030127)
2.2 4.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
2.1 32.1 GO:0042788 polysomal ribosome(GO:0042788)
2.1 31.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
2.1 47.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
2.0 16.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
2.0 37.8 GO:0000242 pericentriolar material(GO:0000242)
1.9 5.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.9 5.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
1.8 38.3 GO:0005682 U5 snRNP(GO:0005682)
1.8 3.6 GO:0005687 U4 snRNP(GO:0005687)
1.7 85.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
1.7 31.0 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152)
1.7 10.2 GO:0070187 telosome(GO:0070187)
1.7 30.5 GO:0000792 heterochromatin(GO:0000792)
1.6 4.9 GO:0005673 transcription factor TFIIE complex(GO:0005673)
1.6 495.7 GO:0000790 nuclear chromatin(GO:0000790)
1.6 1.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.6 128.6 GO:0016605 PML body(GO:0016605)
1.6 115.3 GO:0031985 Golgi cisterna(GO:0031985)
1.6 17.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
1.6 12.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
1.6 12.4 GO:0005677 chromatin silencing complex(GO:0005677)
1.5 4.6 GO:0030905 retromer, tubulation complex(GO:0030905)
1.5 7.4 GO:0033093 Weibel-Palade body(GO:0033093)
1.5 23.2 GO:0032593 insulin-responsive compartment(GO:0032593)
1.4 18.8 GO:0045180 basal cortex(GO:0045180)
1.4 5.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.4 141.2 GO:0005913 cell-cell adherens junction(GO:0005913)
1.4 95.3 GO:0005643 nuclear pore(GO:0005643)
1.4 6.9 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
1.4 10.9 GO:0030014 CCR4-NOT complex(GO:0030014)
1.4 9.5 GO:0042382 paraspeckles(GO:0042382)
1.3 4.0 GO:1990597 TRAF2-GSTP1 complex(GO:0097057) AIP1-IRE1 complex(GO:1990597)
1.3 3.8 GO:0032389 MutLalpha complex(GO:0032389)
1.3 7.6 GO:0034448 EGO complex(GO:0034448)
1.2 105.8 GO:0005814 centriole(GO:0005814)
1.2 24.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
1.2 6.0 GO:0097226 sperm mitochondrial sheath(GO:0097226)
1.2 1.2 GO:0044301 climbing fiber(GO:0044301)
1.2 6.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
1.2 8.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
1.2 13.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
1.1 3.4 GO:0042587 glycogen granule(GO:0042587)
1.1 16.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.1 3.3 GO:0034657 GID complex(GO:0034657)
1.1 4.4 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
1.1 8.7 GO:1990391 DNA repair complex(GO:1990391)
1.1 6.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.1 8.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
1.0 2.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
1.0 6.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
1.0 60.5 GO:0017053 transcriptional repressor complex(GO:0017053)
1.0 8.2 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
1.0 11.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
1.0 8.0 GO:0005787 signal peptidase complex(GO:0005787)
1.0 13.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.0 16.7 GO:0000346 transcription export complex(GO:0000346)
1.0 15.7 GO:0031519 PcG protein complex(GO:0031519)
1.0 18.3 GO:0000775 chromosome, centromeric region(GO:0000775)
0.9 67.8 GO:0005776 autophagosome(GO:0005776)
0.9 9.4 GO:1904115 axon cytoplasm(GO:1904115)
0.9 19.2 GO:0005795 Golgi stack(GO:0005795)
0.9 7.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.9 241.2 GO:0016607 nuclear speck(GO:0016607)
0.9 5.3 GO:0042575 DNA polymerase complex(GO:0042575)
0.9 59.0 GO:0016234 inclusion body(GO:0016234)
0.9 199.3 GO:0005694 chromosome(GO:0005694)
0.9 9.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.9 24.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.9 8.6 GO:0097470 ribbon synapse(GO:0097470)
0.9 3.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.8 0.8 GO:0005767 secondary lysosome(GO:0005767)
0.8 9.3 GO:0032039 integrator complex(GO:0032039)
0.8 4.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.8 5.7 GO:0097452 GAIT complex(GO:0097452)
0.8 9.5 GO:0031209 SCAR complex(GO:0031209)
0.8 3.1 GO:0097447 dendritic tree(GO:0097447)
0.8 2.3 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.8 7.6 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.7 4.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.7 6.6 GO:0000813 ESCRT I complex(GO:0000813)
0.7 3.7 GO:0016589 NURF complex(GO:0016589)
0.7 4.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.7 2.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.7 19.3 GO:0005815 microtubule organizing center(GO:0005815)
0.7 80.4 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.7 11.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.7 5.4 GO:1990752 microtubule end(GO:1990752)
0.7 2.0 GO:0071141 SMAD protein complex(GO:0071141)
0.6 4.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.6 3.6 GO:0030914 STAGA complex(GO:0030914)
0.6 4.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.6 4.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.6 5.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.6 7.9 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.6 5.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.5 3.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.5 3.3 GO:0044308 axonal spine(GO:0044308)
0.5 22.4 GO:0034707 chloride channel complex(GO:0034707)
0.5 31.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.5 10.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.5 9.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.5 2.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.5 2.0 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.5 3.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.5 10.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.5 3.0 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.5 7.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.5 0.5 GO:0098830 presynaptic endosome(GO:0098830)
0.5 0.9 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.5 12.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.5 52.8 GO:0043204 perikaryon(GO:0043204)
0.5 35.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.5 0.9 GO:0034457 Mpp10 complex(GO:0034457)
0.4 1.3 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.4 34.0 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.4 2.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.4 3.0 GO:0031415 NatA complex(GO:0031415)
0.4 5.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.4 3.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.4 1.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.4 10.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.3 2.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.3 19.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 3.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 3.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 1.6 GO:0071817 MMXD complex(GO:0071817)
0.3 2.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.3 1.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 2.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3 1.2 GO:0031983 vesicle lumen(GO:0031983)
0.3 1.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.3 7.0 GO:0097546 ciliary base(GO:0097546)
0.3 1.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 1.5 GO:0097165 nuclear stress granule(GO:0097165)
0.2 3.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.2 7.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 3.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.2 62.0 GO:0005813 centrosome(GO:0005813)
0.2 1.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 5.9 GO:0036064 ciliary basal body(GO:0036064)
0.2 1.4 GO:0097449 astrocyte projection(GO:0097449)
0.2 4.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 0.8 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 3.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 4.5 GO:0005801 cis-Golgi network(GO:0005801)
0.2 871.4 GO:0005634 nucleus(GO:0005634)
0.2 1.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 2.0 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 3.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.7 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 5.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 3.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 7.0 GO:0043198 dendritic shaft(GO:0043198)
0.1 2.7 GO:0030286 dynein complex(GO:0030286)
0.1 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.3 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 1.0 GO:0005770 late endosome(GO:0005770)
0.0 0.7 GO:0005774 vacuolar membrane(GO:0005774)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
47.5 190.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
45.7 182.9 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
37.7 37.7 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
31.6 158.2 GO:0035174 histone serine kinase activity(GO:0035174)
30.1 90.2 GO:0035939 microsatellite binding(GO:0035939)
28.0 112.0 GO:0031493 nucleosomal histone binding(GO:0031493) hemi-methylated DNA-binding(GO:0044729)
27.4 82.1 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
24.9 149.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
22.7 136.5 GO:0050786 RAGE receptor binding(GO:0050786)
20.3 101.4 GO:0043515 kinetochore binding(GO:0043515)
19.0 56.9 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
14.4 114.9 GO:0061676 importin-alpha family protein binding(GO:0061676)
12.8 115.0 GO:0035173 histone kinase activity(GO:0035173)
11.7 23.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
10.4 10.4 GO:0032137 guanine/thymine mispair binding(GO:0032137)
10.3 92.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
9.2 36.8 GO:0048408 epidermal growth factor binding(GO:0048408)
8.9 436.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
8.3 50.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
7.9 31.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
7.8 179.1 GO:0000400 four-way junction DNA binding(GO:0000400)
7.2 64.8 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
7.0 28.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
7.0 34.8 GO:0044547 DNA topoisomerase binding(GO:0044547)
6.8 20.5 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
6.7 93.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
6.6 26.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
6.3 44.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
6.3 18.8 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
6.2 49.5 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
6.0 84.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
6.0 35.9 GO:0070728 leucine binding(GO:0070728)
5.7 34.4 GO:0001069 regulatory region RNA binding(GO:0001069)
5.6 22.4 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
5.6 16.8 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
5.4 16.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
5.3 21.1 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
5.2 41.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
5.1 20.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
5.1 81.3 GO:0003680 AT DNA binding(GO:0003680)
5.1 5.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
5.0 352.3 GO:0003777 microtubule motor activity(GO:0003777)
5.0 19.9 GO:0008142 oxysterol binding(GO:0008142)
4.9 39.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
4.9 19.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
4.7 14.0 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
4.7 88.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
4.5 13.5 GO:0031686 A1 adenosine receptor binding(GO:0031686)
4.4 17.7 GO:1990254 keratin filament binding(GO:1990254)
4.4 17.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
4.3 12.9 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
4.1 12.4 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
4.1 16.3 GO:0070279 vitamin B6 binding(GO:0070279)
4.0 16.1 GO:0004096 aminoacylase activity(GO:0004046) catalase activity(GO:0004096)
4.0 251.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
3.9 15.7 GO:0046790 virion binding(GO:0046790)
3.8 11.5 GO:0030156 benzodiazepine receptor binding(GO:0030156)
3.8 15.2 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
3.7 14.7 GO:0070087 chromo shadow domain binding(GO:0070087)
3.6 126.5 GO:0050699 WW domain binding(GO:0050699)
3.6 21.5 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
3.5 17.6 GO:0004594 pantothenate kinase activity(GO:0004594)
3.5 10.6 GO:0004769 steroid delta-isomerase activity(GO:0004769)
3.4 10.3 GO:0098809 nitrite reductase activity(GO:0098809)
3.4 10.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
3.4 16.9 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
3.3 16.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
3.3 16.4 GO:0015616 DNA translocase activity(GO:0015616)
3.2 9.7 GO:0032564 dATP binding(GO:0032564)
3.2 151.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
3.2 48.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
3.2 19.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
3.2 34.8 GO:0045294 alpha-catenin binding(GO:0045294)
3.1 9.4 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
3.1 9.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
3.1 368.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
3.1 33.7 GO:0008430 selenium binding(GO:0008430)
3.0 21.0 GO:0008301 DNA binding, bending(GO:0008301)
3.0 20.8 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
2.9 32.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
2.9 11.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
2.9 17.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
2.8 73.5 GO:0097602 cullin family protein binding(GO:0097602)
2.8 31.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
2.8 16.6 GO:0048039 ubiquinone binding(GO:0048039)
2.7 18.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
2.5 7.6 GO:0008158 hedgehog receptor activity(GO:0008158)
2.5 27.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
2.4 9.8 GO:0004111 creatine kinase activity(GO:0004111)
2.4 9.7 GO:0003998 acylphosphatase activity(GO:0003998)
2.4 31.3 GO:0031386 protein tag(GO:0031386)
2.4 7.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
2.4 9.6 GO:0070568 guanylyltransferase activity(GO:0070568)
2.4 14.3 GO:0097016 L27 domain binding(GO:0097016)
2.4 9.5 GO:0036435 deubiquitinase activator activity(GO:0035800) K48-linked polyubiquitin binding(GO:0036435)
2.4 42.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
2.3 16.0 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
2.3 9.1 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
2.3 38.6 GO:0005540 hyaluronic acid binding(GO:0005540)
2.3 13.6 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
2.2 6.7 GO:0004743 pyruvate kinase activity(GO:0004743)
2.2 13.1 GO:1990932 5.8S rRNA binding(GO:1990932)
2.2 4.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
2.2 21.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
2.1 8.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
2.1 36.2 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
2.1 6.4 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
2.1 90.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
2.0 150.5 GO:0001047 core promoter binding(GO:0001047)
2.0 12.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
2.0 8.0 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
2.0 45.7 GO:0051787 misfolded protein binding(GO:0051787)
2.0 5.9 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
2.0 7.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.9 15.5 GO:0036310 annealing helicase activity(GO:0036310)
1.9 5.8 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.8 9.2 GO:0043532 angiostatin binding(GO:0043532)
1.8 21.9 GO:0003688 DNA replication origin binding(GO:0003688)
1.8 316.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.8 7.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
1.8 1.8 GO:0032052 bile acid binding(GO:0032052)
1.8 5.4 GO:0016501 prostacyclin receptor activity(GO:0016501)
1.8 5.3 GO:0030984 kininogen binding(GO:0030984)
1.8 24.6 GO:0035198 miRNA binding(GO:0035198)
1.7 40.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.7 12.2 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.7 17.1 GO:0070888 E-box binding(GO:0070888)
1.7 26.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
1.6 3.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
1.6 4.9 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
1.6 1.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.6 93.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
1.6 34.7 GO:0032452 histone demethylase activity(GO:0032452)
1.6 158.8 GO:0042826 histone deacetylase binding(GO:0042826)
1.6 4.7 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
1.5 275.8 GO:0042393 histone binding(GO:0042393)
1.5 16.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.5 19.7 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.5 4.5 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.5 13.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
1.5 45.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
1.5 8.9 GO:0042301 phosphate ion binding(GO:0042301)
1.5 26.2 GO:0015026 coreceptor activity(GO:0015026)
1.5 4.4 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
1.4 7.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
1.4 305.1 GO:0008017 microtubule binding(GO:0008017)
1.4 5.6 GO:2001070 starch binding(GO:2001070)
1.4 20.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
1.4 5.5 GO:0047134 phosphotransferase activity, carboxyl group as acceptor(GO:0016774) protein-disulfide reductase activity(GO:0047134)
1.4 6.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
1.4 375.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
1.4 9.5 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
1.4 44.7 GO:0017091 AU-rich element binding(GO:0017091)
1.4 4.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
1.3 54.8 GO:0003684 damaged DNA binding(GO:0003684)
1.3 7.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.3 6.5 GO:0050700 CARD domain binding(GO:0050700)
1.3 3.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.3 5.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
1.3 8.9 GO:0015925 galactosidase activity(GO:0015925)
1.3 5.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
1.3 3.8 GO:0005134 interleukin-2 receptor binding(GO:0005134)
1.2 14.9 GO:0030881 beta-2-microglobulin binding(GO:0030881)
1.2 3.7 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
1.2 9.6 GO:0016885 ligase activity, forming carbon-carbon bonds(GO:0016885)
1.2 47.7 GO:0030170 pyridoxal phosphate binding(GO:0030170)
1.2 4.6 GO:1990460 leptin receptor binding(GO:1990460)
1.2 1.2 GO:0003681 bent DNA binding(GO:0003681)
1.2 9.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
1.1 10.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.1 7.9 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
1.1 3.3 GO:0004994 somatostatin receptor activity(GO:0004994)
1.1 17.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.1 5.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
1.1 9.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
1.1 5.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
1.0 10.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
1.0 9.2 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
1.0 6.1 GO:0043522 leucine zipper domain binding(GO:0043522)
1.0 66.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
1.0 8.0 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
1.0 29.9 GO:0048487 beta-tubulin binding(GO:0048487)
1.0 9.0 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
1.0 3.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.0 3.9 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.0 19.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
1.0 5.8 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.0 2.9 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.9 3.7 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.9 5.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.9 4.5 GO:0089720 caspase binding(GO:0089720)
0.9 5.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.9 12.0 GO:0070840 dynein complex binding(GO:0070840)
0.9 5.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.8 1.7 GO:0097100 supercoiled DNA binding(GO:0097100)
0.8 16.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.8 9.2 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.8 5.7 GO:0005047 signal recognition particle binding(GO:0005047)
0.8 18.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.8 26.7 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.8 2.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.8 15.8 GO:0050681 androgen receptor binding(GO:0050681)
0.7 2.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.7 7.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.7 4.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.7 3.7 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.7 5.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.7 4.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.7 17.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.7 3.5 GO:0004849 uridine kinase activity(GO:0004849)
0.7 3.5 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.7 53.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.7 4.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.7 30.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.7 21.0 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.6 20.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.6 43.3 GO:0005080 protein kinase C binding(GO:0005080)
0.6 1.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.6 22.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.6 3.7 GO:0050733 RS domain binding(GO:0050733)
0.6 3.7 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.6 4.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.6 6.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.6 2.4 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.6 4.2 GO:0001515 opioid peptide activity(GO:0001515)
0.6 3.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.6 3.0 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.6 2.9 GO:0008172 S-methyltransferase activity(GO:0008172)
0.6 5.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.6 2.3 GO:0050436 microfibril binding(GO:0050436)
0.6 2.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.6 3.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.6 6.1 GO:0043495 protein anchor(GO:0043495)
0.6 29.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.6 5.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.5 2.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.5 1.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.5 4.8 GO:0008420 CTD phosphatase activity(GO:0008420)
0.5 5.7 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5 6.7 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.5 2.5 GO:0045545 syndecan binding(GO:0045545)
0.5 4.0 GO:0031996 thioesterase binding(GO:0031996)
0.5 6.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.5 1.4 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.5 1.9 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.5 43.1 GO:0004386 helicase activity(GO:0004386)
0.5 9.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.5 1.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.5 1.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.5 0.9 GO:0030519 snoRNP binding(GO:0030519)
0.5 29.3 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.4 1.8 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.4 1.3 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.4 12.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 6.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.4 3.4 GO:0031690 adrenergic receptor binding(GO:0031690)
0.4 4.7 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.4 63.1 GO:0017124 SH3 domain binding(GO:0017124)
0.4 5.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.4 8.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.4 7.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.4 2.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.4 101.7 GO:0003682 chromatin binding(GO:0003682)
0.4 7.0 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.4 2.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.4 0.8 GO:0070976 TIR domain binding(GO:0070976)
0.4 2.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.4 14.4 GO:0003774 motor activity(GO:0003774)
0.4 2.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 2.7 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.4 1.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.4 30.1 GO:0019905 syntaxin binding(GO:0019905)
0.4 45.5 GO:0005516 calmodulin binding(GO:0005516)
0.4 17.8 GO:0005179 hormone activity(GO:0005179)
0.4 1.1 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.4 27.9 GO:0008083 growth factor activity(GO:0008083)
0.3 28.9 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.3 6.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 1.3 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3 4.1 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.3 2.8 GO:0043422 protein kinase B binding(GO:0043422)
0.3 6.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.3 1.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3 1.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 6.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 4.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.3 3.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.3 3.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 41.2 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.3 3.0 GO:0004707 MAP kinase activity(GO:0004707)
0.3 6.0 GO:0030506 ankyrin binding(GO:0030506)
0.3 11.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 0.8 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.3 2.3 GO:0015643 toxic substance binding(GO:0015643)
0.3 1.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 1.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 66.4 GO:0045296 cadherin binding(GO:0045296)
0.2 2.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 0.7 GO:0005113 patched binding(GO:0005113)
0.2 4.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171)
0.2 1.5 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.2 5.1 GO:0005112 Notch binding(GO:0005112)
0.2 1.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.2 0.8 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.2 0.6 GO:0030249 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.2 0.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 0.8 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 1.5 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.2 2.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 2.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.2 17.9 GO:0051015 actin filament binding(GO:0051015)
0.2 0.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 0.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 2.1 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.2 0.6 GO:0004312 fatty acid synthase activity(GO:0004312)
0.2 5.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 129.7 GO:0003677 DNA binding(GO:0003677)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 3.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 3.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 43.9 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 3.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.1 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 5.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.2 GO:0002039 p53 binding(GO:0002039)
0.1 1.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 36.1 GO:0019904 protein domain specific binding(GO:0019904)
0.1 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0070404 NADH binding(GO:0070404)
0.1 0.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.4 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 2.0 GO:0005504 fatty acid binding(GO:0005504)
0.1 2.6 GO:0000149 SNARE binding(GO:0000149)
0.1 0.2 GO:0016215 acyl-CoA desaturase activity(GO:0016215)
0.1 0.3 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.1 0.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 6.4 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 2.4 GO:0009055 electron carrier activity(GO:0009055)
0.1 1.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.5 GO:0043621 protein self-association(GO:0043621)
0.1 0.2 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 0.6 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.3 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 4.5 GO:0061659 ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.6 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
19.7 1243.3 PID_PLK1_PATHWAY PLK1 signaling events
12.8 179.4 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
9.9 364.7 PID_AURORA_A_PATHWAY Aurora A signaling
5.4 236.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
5.2 301.3 PID_IL12_2PATHWAY IL12-mediated signaling events
4.8 133.9 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
4.1 134.6 PID_AURORA_B_PATHWAY Aurora B signaling
3.6 149.2 PID_FANCONI_PATHWAY Fanconi anemia pathway
3.4 98.8 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
3.2 32.5 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
2.8 52.7 PID_MYC_PATHWAY C-MYC pathway
2.5 181.0 PID_TELOMERASE_PATHWAY Regulation of Telomerase
2.4 7.1 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
2.4 47.0 PID_FOXM1_PATHWAY FOXM1 transcription factor network
2.3 114.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
2.1 10.6 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
2.1 92.8 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
2.1 8.4 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
2.1 24.8 PID_S1P_S1P4_PATHWAY S1P4 pathway
1.9 51.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
1.6 89.9 PID_E2F_PATHWAY E2F transcription factor network
1.6 52.8 PID_RAS_PATHWAY Regulation of Ras family activation
1.5 1.5 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
1.3 38.9 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
1.2 37.2 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
1.2 3.6 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
1.2 17.5 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.1 48.4 PID_RHOA_PATHWAY RhoA signaling pathway
1.1 9.0 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
1.1 60.3 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
1.1 9.8 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
1.1 11.7 PID_BCR_5PATHWAY BCR signaling pathway
1.0 2.9 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.9 11.2 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.9 13.9 PID_RAC1_PATHWAY RAC1 signaling pathway
0.9 50.3 PID_CDC42_PATHWAY CDC42 signaling events
0.8 51.7 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.8 18.6 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.8 29.3 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.7 6.7 PID_IL5_PATHWAY IL5-mediated signaling events
0.7 15.4 PID_FOXO_PATHWAY FoxO family signaling
0.7 10.5 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.7 8.7 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.6 36.5 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.6 9.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.6 6.3 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.6 2.8 PID_IL23_PATHWAY IL23-mediated signaling events
0.5 6.6 PID_CD40_PATHWAY CD40/CD40L signaling
0.5 11.1 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.5 9.2 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.5 24.0 PID_CMYB_PATHWAY C-MYB transcription factor network
0.5 17.8 PID_BMP_PATHWAY BMP receptor signaling
0.4 16.9 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.4 13.3 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.4 12.3 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.4 6.8 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.4 2.1 PID_IL3_PATHWAY IL3-mediated signaling events
0.3 8.0 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.3 6.2 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.3 11.7 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.3 1.9 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.3 3.5 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.3 3.5 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 3.7 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.3 4.3 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.2 6.5 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.2 4.2 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.6 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 4.5 PID_MTOR_4PATHWAY mTOR signaling pathway
0.1 1.9 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 1.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 1.4 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 1.5 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.7 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.8 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.1 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
22.1 375.1 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
15.8 47.4 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
15.6 249.1 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
11.5 11.5 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
11.0 296.7 REACTOME_KINESINS Genes involved in Kinesins
10.7 236.3 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
10.5 167.9 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
9.6 86.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
8.0 770.9 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
7.5 90.6 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
7.2 374.3 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
6.9 83.1 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
6.4 89.0 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
5.7 113.9 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
5.0 49.5 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
4.6 73.3 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
4.3 349.7 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
4.0 44.3 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
3.9 82.9 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
3.7 7.4 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
3.5 79.8 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
3.1 79.4 REACTOME_G1_PHASE Genes involved in G1 Phase
3.0 21.3 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
2.3 25.3 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
2.3 125.9 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
2.2 9.0 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
2.2 57.0 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
2.0 22.3 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.7 22.6 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.7 89.5 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
1.6 16.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
1.6 140.4 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
1.6 8.0 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
1.6 55.1 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
1.4 58.3 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
1.4 9.6 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.3 18.3 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
1.2 13.4 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
1.2 33.7 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
1.2 33.3 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
1.1 21.7 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.1 21.6 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
1.1 83.8 REACTOME_GLUCOSE_METABOLISM Genes involved in Glucose metabolism
1.1 23.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
1.1 10.5 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
1.0 15.6 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
1.0 64.3 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.9 6.3 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.9 20.6 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.9 7.9 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.8 16.1 REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.8 4.2 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.8 3.3 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.8 4.0 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.8 8.8 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.8 11.0 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.8 2.4 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.7 8.6 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.7 10.5 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.7 24.3 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.6 10.9 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.6 16.9 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.6 16.2 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.6 7.0 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.6 5.1 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.6 15.4 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.5 7.1 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.5 40.5 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.5 19.8 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.5 4.2 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.5 3.7 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.4 6.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.4 7.4 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.4 6.5 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4 19.4 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.4 7.5 REACTOME_PERK_REGULATED_GENE_EXPRESSION Genes involved in PERK regulated gene expression
0.3 2.7 REACTOME_G2_M_CHECKPOINTS Genes involved in G2/M Checkpoints
0.3 2.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.3 3.3 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.3 2.9 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.3 3.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.3 26.5 REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.3 10.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3 6.0 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 0.7 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.2 35.8 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.2 11.3 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 3.6 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 2.6 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 1.8 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 1.1 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.2 1.9 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.2 1.8 REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM Genes involved in Bile acid and bile salt metabolism
0.2 0.8 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 3.4 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 3.8 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 9.4 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 1.2 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 3.9 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.9 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.4 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 0.9 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.1 4.2 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 13.8 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY Genes involved in Generic Transcription Pathway
0.1 2.2 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 6.4 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 1.3 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.5 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.1 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 2.1 REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.2 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.5 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism