Motif ID: Zbtb3

Z-value: 0.504


Transcription factors associated with Zbtb3:

Gene SymbolEntrez IDGene Name
Zbtb3 ENSMUSG00000071661.6 Zbtb3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb3mm10_v2_chr19_+_8802486_88025300.271.7e-02Click!


Activity profile for motif Zbtb3.

activity profile for motif Zbtb3


Sorted Z-values histogram for motif Zbtb3

Sorted Z-values for motif Zbtb3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_172043466 3.297 ENSMUST00000087950.3
 Cbln4
cerebellin 4 precursor protein
chr8_+_10272572 2.868 ENSMUST00000042103.8
 Myo16
myosin XVI
chr7_-_103843154 2.622 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr9_-_97018823 2.615 ENSMUST00000055433.4
 Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr15_+_98167806 2.600 ENSMUST00000031914.4
 AI836003
expressed sequence AI836003
chr15_-_66969616 2.018 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr19_-_58455903 2.015 ENSMUST00000131877.1
 Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr2_-_25627960 1.925 ENSMUST00000028307.8
 Fcna
ficolin A
chr17_+_46254017 1.408 ENSMUST00000095262.4
 Lrrc73
leucine rich repeat containing 73
chr5_-_138996087 1.351 ENSMUST00000110897.1
 Pdgfa
platelet derived growth factor, alpha
chr10_+_60346851 1.342 ENSMUST00000020301.7
ENSMUST00000105460.1
ENSMUST00000170507.1
 4632428N05Rik


RIKEN cDNA 4632428N05 gene


chrX_+_53607918 1.284 ENSMUST00000114827.1
 Cxx1c
CAAX box 1C
chr8_+_83715504 1.265 ENSMUST00000109810.1
 Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chrX_+_53607987 1.241 ENSMUST00000063384.3
ENSMUST00000169626.1
 Cxx1c

CAAX box 1C

chr14_-_26067355 1.206 ENSMUST00000100819.5
 Tmem254c
transmembrane protein 254c
chr7_+_24507122 1.202 ENSMUST00000177205.1
 Zfp428
zinc finger protein 428
chr8_+_83715177 1.200 ENSMUST00000019576.8
 Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr14_-_104467984 1.168 ENSMUST00000053016.8
 Pou4f1
POU domain, class 4, transcription factor 1
chr7_+_19024387 1.098 ENSMUST00000153976.1
 Sympk
symplekin
chr5_+_37242025 1.056 ENSMUST00000114158.2
 Crmp1
collapsin response mediator protein 1
chr7_+_24507057 1.054 ENSMUST00000071361.6
 Zfp428
zinc finger protein 428
chr9_+_78191966 1.054 ENSMUST00000034903.5
 Gsta4
glutathione S-transferase, alpha 4
chr2_-_127792467 1.043 ENSMUST00000135091.1
 1500011K16Rik
RIKEN cDNA 1500011K16 gene
chr8_-_95888510 0.945 ENSMUST00000034097.7
 Got2
glutamate oxaloacetate transaminase 2, mitochondrial
chr11_+_73177083 0.916 ENSMUST00000040687.5
 Tax1bp3
Tax1 (human T cell leukemia virus type I) binding protein 3
chr7_+_19024364 0.910 ENSMUST00000023882.7
 Sympk
symplekin
chr9_+_66946057 0.876 ENSMUST00000040917.7
ENSMUST00000127896.1
 Rps27l

ribosomal protein S27-like

chr10_+_74967164 0.838 ENSMUST00000037813.4
 Gnaz
guanine nucleotide binding protein, alpha z subunit
chr7_+_24507099 0.826 ENSMUST00000177228.1
 Zfp428
zinc finger protein 428
chr3_-_51408925 0.825 ENSMUST00000038108.6
 Ndufc1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1
chr15_-_72546279 0.809 ENSMUST00000044624.6
 Kcnk9
potassium channel, subfamily K, member 9
chr5_-_137531952 0.805 ENSMUST00000140139.1
 Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr11_-_3774706 0.799 ENSMUST00000155197.1
 Osbp2
oxysterol binding protein 2
chr11_-_59787636 0.766 ENSMUST00000125307.1
 Pld6
phospholipase D family, member 6
chr6_-_147264124 0.760 ENSMUST00000052296.6
 Pthlh
parathyroid hormone-like peptide
chr11_+_51967649 0.759 ENSMUST00000102763.4
 Cdkn2aipnl
CDKN2A interacting protein N-terminal like
chr18_+_37307445 0.751 ENSMUST00000056712.2
 Pcdhb4
protocadherin beta 4
chr11_+_6561133 0.741 ENSMUST00000160633.1
 Ccm2
cerebral cavernous malformation 2
chr15_+_103272893 0.739 ENSMUST00000100162.3
 Copz1
coatomer protein complex, subunit zeta 1
chr10_+_61695503 0.730 ENSMUST00000020284.4
 Tysnd1
trypsin domain containing 1
chr8_+_64947177 0.727 ENSMUST00000079896.7
ENSMUST00000026595.5
 Tmem192

transmembrane protein 192

chr2_+_80617045 0.726 ENSMUST00000028384.4
 Dusp19
dual specificity phosphatase 19
chr16_+_20589471 0.719 ENSMUST00000100074.3
ENSMUST00000096197.4
 Vwa5b2

von Willebrand factor A domain containing 5B2

chr8_+_114439655 0.715 ENSMUST00000004756.7
ENSMUST00000109108.2
ENSMUST00000160862.1
ENSMUST00000109107.2
 Wwox



WW domain-containing oxidoreductase



chr14_-_19977040 0.706 ENSMUST00000159028.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr7_-_80387935 0.706 ENSMUST00000080932.6
 Fes
feline sarcoma oncogene
chr11_-_120731944 0.701 ENSMUST00000154565.1
ENSMUST00000026148.2
 Cbr2

carbonyl reductase 2

chr15_-_79774408 0.701 ENSMUST00000023055.6
 Dnal4
dynein, axonemal, light chain 4
chr5_+_115908644 0.700 ENSMUST00000141101.1
 Cit
citron
chr14_-_19977151 0.691 ENSMUST00000055100.7
ENSMUST00000162425.1
 Gng2

guanine nucleotide binding protein (G protein), gamma 2

chrX_-_155216444 0.679 ENSMUST00000026318.8
 Sat1
spermidine/spermine N1-acetyl transferase 1
chr11_+_6561178 0.663 ENSMUST00000109721.2
 Ccm2
cerebral cavernous malformation 2
chr16_+_11405648 0.657 ENSMUST00000096273.2
 Snx29
sorting nexin 29
chr17_-_57031468 0.650 ENSMUST00000007814.8
 Khsrp
KH-type splicing regulatory protein
chr19_+_25236959 0.634 ENSMUST00000049400.8
 Kank1
KN motif and ankyrin repeat domains 1
chr5_-_90223923 0.623 ENSMUST00000118816.1
ENSMUST00000048363.7
 Cox18

cytochrome c oxidase assembly protein 18

chr13_-_54468805 0.609 ENSMUST00000026990.5
 Thoc3
THO complex 3
chr19_-_34877880 0.601 ENSMUST00000112460.1
 Pank1
pantothenate kinase 1
chr4_-_132533488 0.599 ENSMUST00000152993.1
ENSMUST00000067496.6
 Atpif1

ATPase inhibitory factor 1

chr5_+_30588078 0.598 ENSMUST00000066295.2
 Kcnk3
potassium channel, subfamily K, member 3
chr10_+_82954344 0.591 ENSMUST00000095396.3
 Gm4799
predicted gene 4799
chr11_+_98809787 0.587 ENSMUST00000169695.1
 Casc3
cancer susceptibility candidate 3
chr3_-_57847478 0.579 ENSMUST00000120289.1
ENSMUST00000066882.8
 Pfn2

profilin 2

chr16_-_76403673 0.574 ENSMUST00000052867.7
 Gm9843
predicted gene 9843
chr19_-_5457397 0.574 ENSMUST00000179549.1
 Ccdc85b
coiled-coil domain containing 85B
chr7_-_122101735 0.556 ENSMUST00000139456.1
ENSMUST00000106471.2
ENSMUST00000123296.1
ENSMUST00000033157.3
 Ndufab1



NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1



chr15_-_67113909 0.549 ENSMUST00000092640.5
 St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr1_-_173367638 0.547 ENSMUST00000005470.4
ENSMUST00000111220.1
 Cadm3

cell adhesion molecule 3

chr9_+_75625707 0.544 ENSMUST00000034702.4
 Lysmd2
LysM, putative peptidoglycan-binding, domain containing 2
chr4_-_129662442 0.516 ENSMUST00000003828.4
 Kpna6
karyopherin (importin) alpha 6
chr18_+_24603952 0.513 ENSMUST00000025120.6
 Elp2
elongator acetyltransferase complex subunit 2
chr15_-_79774383 0.508 ENSMUST00000069877.5
 Dnal4
dynein, axonemal, light chain 4
chr7_-_141443989 0.505 ENSMUST00000026580.5
 Lrdd
leucine-rich and death domain containing
chr12_-_27160311 0.504 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
 Gm9866


predicted gene 9866


chr11_-_119040905 0.494 ENSMUST00000026663.7
 Cbx8
chromobox 8
chr7_+_97400003 0.463 ENSMUST00000032882.8
 Ndufc2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
chr15_-_76723814 0.457 ENSMUST00000036247.8
 C030006K11Rik
RIKEN cDNA C030006K11 gene
chr5_+_146948640 0.452 ENSMUST00000146511.1
ENSMUST00000132102.1
 Gtf3a

general transcription factor III A

chr10_+_81559447 0.450 ENSMUST00000002518.8
 Aes
amino-terminal enhancer of split
chr16_+_4939099 0.443 ENSMUST00000050881.8
 Nudt16l1
nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
chr11_+_106066055 0.440 ENSMUST00000002048.7
 Taco1
translational activator of mitochondrially encoded cytochrome c oxidase I
chr15_+_39076885 0.427 ENSMUST00000067072.3
 Cthrc1
collagen triple helix repeat containing 1
chr7_+_101905837 0.426 ENSMUST00000033131.6
 Lamtor1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chrX_-_155216338 0.414 ENSMUST00000112551.3
 Sat1
spermidine/spermine N1-acetyl transferase 1
chr2_-_151744142 0.412 ENSMUST00000109869.1
 Psmf1
proteasome (prosome, macropain) inhibitor subunit 1
chr12_-_72664759 0.408 ENSMUST00000021512.9
 Dhrs7
dehydrogenase/reductase (SDR family) member 7
chr6_+_122819888 0.400 ENSMUST00000003238.7
 Foxj2
forkhead box J2
chr5_+_33658567 0.385 ENSMUST00000114426.3
 Tacc3
transforming, acidic coiled-coil containing protein 3
chr13_+_67863324 0.385 ENSMUST00000078471.5
 BC048507
cDNA sequence BC048507
chr5_-_38159457 0.375 ENSMUST00000031009.4
 Nsg1
neuron specific gene family member 1
chr11_+_88973928 0.372 ENSMUST00000036649.4
ENSMUST00000107898.3
 Coil

coilin

chr8_+_83715239 0.372 ENSMUST00000172396.1
 Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr8_-_64693027 0.360 ENSMUST00000048967.7
 Cpe
carboxypeptidase E
chr8_-_70439557 0.350 ENSMUST00000076615.5
 Crtc1
CREB regulated transcription coactivator 1
chr11_-_5741141 0.345 ENSMUST00000140922.1
ENSMUST00000093362.5
 Urgcp

upregulator of cell proliferation

chr7_-_45434590 0.334 ENSMUST00000107771.3
ENSMUST00000141761.1
 Ruvbl2

RuvB-like protein 2

chr4_-_40853950 0.325 ENSMUST00000030121.6
ENSMUST00000108096.2
 B4galt1

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1

chr2_-_157571270 0.325 ENSMUST00000173378.1
 Blcap
bladder cancer associated protein homolog (human)
chr18_-_80469664 0.309 ENSMUST00000036229.6
 Ctdp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr7_+_44849216 0.302 ENSMUST00000054343.8
 Akt1s1
AKT1 substrate 1 (proline-rich)
chr10_-_78412949 0.266 ENSMUST00000062678.9
 Rrp1
ribosomal RNA processing 1 homolog (S. cerevisiae)
chrX_+_36874351 0.261 ENSMUST00000016452.7
 Ube2a
ubiquitin-conjugating enzyme E2A
chr7_+_44848991 0.255 ENSMUST00000107885.1
 Akt1s1
AKT1 substrate 1 (proline-rich)
chr11_-_119086221 0.249 ENSMUST00000026665.7
 Cbx4
chromobox 4
chr1_-_172258410 0.235 ENSMUST00000111243.1
 Atp1a4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr4_-_44167988 0.217 ENSMUST00000143337.1
 Rnf38
ring finger protein 38
chr4_-_150008977 0.215 ENSMUST00000030830.3
 H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr6_-_28421680 0.208 ENSMUST00000090511.3
 Gcc1
golgi coiled coil 1
chr9_+_32116040 0.194 ENSMUST00000174641.1
 Arhgap32
Rho GTPase activating protein 32
chr7_-_118995211 0.174 ENSMUST00000008878.8
 Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr9_-_45984816 0.167 ENSMUST00000172450.1
 Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr14_-_19977249 0.167 ENSMUST00000160013.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr11_-_86671169 0.164 ENSMUST00000143991.1
 Vmp1
vacuole membrane protein 1
chr11_-_102185202 0.161 ENSMUST00000107156.2
 Lsm12
LSM12 homolog (S. cerevisiae)
chr19_+_5038826 0.151 ENSMUST00000053705.6
 B3gnt1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr7_-_23947237 0.151 ENSMUST00000086013.2
 Gm10175
predicted gene 10175
chr8_+_83955507 0.137 ENSMUST00000005607.8
 Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr11_-_102185239 0.112 ENSMUST00000021297.5
 Lsm12
LSM12 homolog (S. cerevisiae)
chr10_+_70097102 0.111 ENSMUST00000147545.1
 Ccdc6
coiled-coil domain containing 6
chr13_+_99100698 0.111 ENSMUST00000181742.1
 Gm807
predicted gene 807
chr13_+_76579670 0.097 ENSMUST00000126960.1
ENSMUST00000109583.2
 Mctp1

multiple C2 domains, transmembrane 1

chr8_-_109693235 0.096 ENSMUST00000034164.4
 Ist1
increased sodium tolerance 1 homolog (yeast)
chr2_-_51973219 0.093 ENSMUST00000028314.2
 Nmi
N-myc (and STAT) interactor
chr11_+_87592145 0.092 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
 Mtmr4


myotubularin related protein 4


chr18_-_52529692 0.092 ENSMUST00000025409.7
 Lox
lysyl oxidase
chr11_+_116030304 0.084 ENSMUST00000021116.5
ENSMUST00000106452.1
 Unk

unkempt homolog (Drosophila)

chr19_-_4175470 0.067 ENSMUST00000167055.1
 Carns1
carnosine synthase 1
chr15_+_76797628 0.060 ENSMUST00000165535.2
 Gm17271
predicted gene, 17271
chr1_-_121332571 0.049 ENSMUST00000071064.6
 Insig2
insulin induced gene 2
chr16_-_59639124 0.044 ENSMUST00000149797.1
ENSMUST00000023405.9
 Arl6

ADP-ribosylation factor-like 6

chr7_+_45434876 0.013 ENSMUST00000107766.1
 Gys1
glycogen synthase 1, muscle
chr7_-_44849075 0.011 ENSMUST00000047085.8
 Tbc1d17
TBC1 domain family, member 17
chr5_+_141856692 0.010 ENSMUST00000074546.6
 Sdk1
sidekick homolog 1 (chicken)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.6 GO:0015671 oxygen transport(GO:0015671)
0.5 1.4 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.4 1.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 0.9 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.3 1.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 1.1 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.2 0.7 GO:0006116 NADH oxidation(GO:0006116)
0.2 1.2 GO:0019230 proprioception(GO:0019230)
0.2 0.6 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 2.0 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.2 0.8 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.1 1.6 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 1.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.8 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.4 GO:0030070 insulin processing(GO:0030070)
0.1 0.6 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.3 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.3 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.3 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 1.4 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.1 0.6 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.4 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 0.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.4 GO:0032439 endosome localization(GO:0032439) regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.6 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.6 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 3.4 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 2.0 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.6 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.7 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.4 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.7 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.7 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.7 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0009838 abscission(GO:0009838)
0.0 0.2 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.0 1.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:1902524 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.0 0.4 GO:0030953 astral microtubule organization(GO:0030953)
0.0 2.6 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.8 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.3 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 2.0 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.0 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 GO:0005833 hemoglobin complex(GO:0005833)
0.2 2.0 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 2.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 2.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 2.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 2.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.4 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 1.6 GO:0030286 dynein complex(GO:0030286)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.6 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 2.1 GO:0005902 microvillus(GO:0005902)
0.0 1.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.8 GO:0097440 apical dendrite(GO:0097440)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 1.7 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.6 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.4 1.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.3 0.9 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.2 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.7 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.9 GO:0008494 translation activator activity(GO:0008494)
0.1 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.6 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 1.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.1 GO:0031005 filamin binding(GO:0031005)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 1.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 2.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 2.8 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.2 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 2.7 GO:0003774 motor activity(GO:0003774)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.4 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.6 GO:0019842 vitamin binding(GO:0019842)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.1 0.8 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.5 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 2.0 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.4 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.8 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.0 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.2 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 1.4 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.4 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 1.2 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.4 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.7 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.7 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 2.1 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.8 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.5 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.1 1.1 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.7 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.2 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 0.5 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 2.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.9 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.8 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.4 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 3.3 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres