Motif ID: Zbtb7c
Z-value: 0.663

Transcription factors associated with Zbtb7c:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Zbtb7c | ENSMUSG00000044646.8 | Zbtb7c |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Zbtb7c | mm10_v2_chr18_+_75820174_75820210 | -0.10 | 4.0e-01 | Click! |
Top targets:
Showing 1 to 20 of 138 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 62 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 12.7 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
0.0 | 10.3 | GO:0000122 | negative regulation of transcription from RNA polymerase II promoter(GO:0000122) |
0.5 | 8.5 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
0.0 | 7.4 | GO:0071805 | potassium ion transmembrane transport(GO:0071805) |
0.3 | 6.7 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.1 | 4.9 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.1 | 4.7 | GO:0015807 | L-amino acid transport(GO:0015807) |
0.5 | 3.6 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
1.2 | 3.5 | GO:1902022 | L-lysine transport(GO:1902022) |
0.2 | 3.3 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
0.3 | 3.0 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
1.0 | 2.9 | GO:0006566 | threonine metabolic process(GO:0006566) |
0.4 | 2.9 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
0.2 | 2.9 | GO:0048875 | chemical homeostasis within a tissue(GO:0048875) |
0.0 | 2.9 | GO:0007409 | axonogenesis(GO:0007409) |
0.2 | 2.8 | GO:0035646 | endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757) |
0.0 | 2.8 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
0.1 | 2.7 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
0.0 | 2.6 | GO:0007411 | axon guidance(GO:0007411) |
0.2 | 2.4 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 31 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 12.7 | GO:0045298 | tubulin complex(GO:0045298) |
0.1 | 8.5 | GO:0001650 | fibrillar center(GO:0001650) |
0.1 | 8.2 | GO:0030118 | clathrin coat(GO:0030118) |
1.4 | 6.9 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
0.7 | 6.7 | GO:0032591 | dendritic spine membrane(GO:0032591) |
0.1 | 4.8 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.1 | 2.9 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.1 | 2.9 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.1 | 2.9 | GO:0043034 | costamere(GO:0043034) |
0.4 | 2.7 | GO:0008091 | spectrin(GO:0008091) |
0.3 | 2.6 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
0.1 | 2.4 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
0.4 | 2.1 | GO:0001533 | cornified envelope(GO:0001533) |
0.4 | 1.7 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
0.1 | 1.6 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.1 | 1.4 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.0 | 1.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 1.3 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
0.4 | 1.2 | GO:1990257 | piccolo-bassoon transport vesicle(GO:1990257) |
0.0 | 1.1 | GO:0005604 | basement membrane(GO:0005604) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 47 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.8 | 12.7 | GO:0099609 | microtubule lateral binding(GO:0099609) |
0.3 | 9.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 8.7 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.7 | 8.5 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.0 | 6.9 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.1 | 5.5 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
0.1 | 4.7 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.0 | 4.3 | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810) |
0.0 | 3.9 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.9 | 3.5 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
0.0 | 3.3 | GO:0030246 | carbohydrate binding(GO:0030246) |
0.1 | 3.0 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
1.0 | 2.9 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
0.3 | 2.9 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.1 | 2.7 | GO:0030506 | ankyrin binding(GO:0030506) |
0.2 | 2.6 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 2.4 | GO:0044325 | ion channel binding(GO:0044325) |
0.1 | 2.3 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 2.2 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
0.0 | 2.1 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
Gene overrepresentation in C2:CP category:
Showing 1 to 8 of 8 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 12.7 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
0.3 | 11.5 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.2 | 8.5 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
0.1 | 4.7 | PID_AP1_PATHWAY | AP-1 transcription factor network |
0.1 | 2.8 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 2.8 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
0.0 | 1.4 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 1.0 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 20 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 12.7 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.2 | 8.5 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
0.2 | 8.1 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.1 | 6.9 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.1 | 5.5 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.4 | 5.2 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.2 | 4.3 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.4 | 3.0 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
0.1 | 2.9 | REACTOME_KINESINS | Genes involved in Kinesins |
0.1 | 2.7 | REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH | Genes involved in NCAM signaling for neurite out-growth |
0.0 | 2.5 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
0.1 | 1.9 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 1.7 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.1 | 1.3 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.0 | 1.0 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.1 | 0.9 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
0.0 | 0.9 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.0 | 0.9 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.0 | 0.7 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 0.4 | REACTOME_KERATAN_SULFATE_BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |