Motif ID: Zbtb7c

Z-value: 0.663


Transcription factors associated with Zbtb7c:

Gene SymbolEntrez IDGene Name
Zbtb7c ENSMUSG00000044646.8 Zbtb7c

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb7cmm10_v2_chr18_+_75820174_75820210-0.104.0e-01Click!


Activity profile for motif Zbtb7c.

activity profile for motif Zbtb7c


Sorted Z-values histogram for motif Zbtb7c

Sorted Z-values for motif Zbtb7c



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb7c

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_32938955 8.469 ENSMUST00000042868.4
Camk4
calcium/calmodulin-dependent protein kinase IV
chr6_+_51432678 7.420 ENSMUST00000160133.1
Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr16_+_11984581 6.745 ENSMUST00000170672.2
ENSMUST00000023138.7
Shisa9

shisa homolog 9 (Xenopus laevis)

chr6_+_51432663 5.679 ENSMUST00000005103.5
Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr1_-_21961581 5.402 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr7_-_19310035 4.943 ENSMUST00000003640.2
Fosb
FBJ osteosarcoma oncogene B
chr11_+_104231465 4.421 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr11_+_104231573 4.209 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chr11_+_104231515 4.092 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chr8_-_11312731 3.600 ENSMUST00000033898.9
Col4a1
collagen, type IV, alpha 1
chr7_+_5056706 3.494 ENSMUST00000144802.1
Ccdc106
coiled-coil domain containing 106
chr8_+_40862379 3.460 ENSMUST00000098816.3
ENSMUST00000057784.8
ENSMUST00000141505.1
Slc7a2


solute carrier family 7 (cationic amino acid transporter, y+ system), member 2


chr11_-_26210553 3.288 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr8_+_11312805 3.260 ENSMUST00000033899.7
Col4a2
collagen, type IV, alpha 2
chr2_-_118703963 3.135 ENSMUST00000104937.1
Ankrd63
ankyrin repeat domain 63
chr12_+_108334341 3.007 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr2_-_29253001 2.923 ENSMUST00000071201.4
Ntng2
netrin G2
chr11_-_117873433 2.921 ENSMUST00000033230.7
Tha1
threonine aldolase 1
chr10_-_127263346 2.917 ENSMUST00000099172.3
Kif5a
kinesin family member 5A
chr12_+_81859964 2.909 ENSMUST00000021567.5
Pcnx
pecanex homolog (Drosophila)
chr4_-_120287349 2.767 ENSMUST00000102656.3
Foxo6
forkhead box O6
chr12_-_76709997 2.681 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr7_+_5057161 2.582 ENSMUST00000045543.5
Ccdc106
coiled-coil domain containing 106
chr7_+_5056856 2.560 ENSMUST00000131368.1
ENSMUST00000123956.1
Ccdc106

coiled-coil domain containing 106

chr9_+_100643755 2.515 ENSMUST00000133388.1
Stag1
stromal antigen 1
chr19_-_5273080 2.449 ENSMUST00000025786.7
Pacs1
phosphofurin acidic cluster sorting protein 1
chr6_+_135198034 2.316 ENSMUST00000130612.1
8430419L09Rik
RIKEN cDNA 8430419L09 gene
chr2_-_45117349 2.311 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr11_+_75531690 2.310 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
Slc43a2



solute carrier family 43, member 2



chr5_+_30711849 2.164 ENSMUST00000088081.4
ENSMUST00000101442.3
Dpysl5

dihydropyrimidinase-like 5

chr5_+_30711564 2.151 ENSMUST00000114729.1
Dpysl5
dihydropyrimidinase-like 5
chr1_-_165460430 2.125 ENSMUST00000027856.7
Dcaf6
DDB1 and CUL4 associated factor 6
chr15_-_101850778 2.072 ENSMUST00000023790.3
Krt1
keratin 1
chr8_+_25911670 1.931 ENSMUST00000120653.1
ENSMUST00000126226.1
Kcnu1

potassium channel, subfamily U, member 1

chr6_+_135197977 1.921 ENSMUST00000111915.1
ENSMUST00000111916.1
8430419L09Rik

RIKEN cDNA 8430419L09 gene

chr4_-_22488296 1.891 ENSMUST00000178174.1
Pou3f2
POU domain, class 3, transcription factor 2
chr11_+_49794157 1.882 ENSMUST00000020629.4
Gfpt2
glutamine fructose-6-phosphate transaminase 2
chr15_-_100599864 1.838 ENSMUST00000177247.2
ENSMUST00000177505.2
Pou6f1

POU domain, class 6, transcription factor 1

chr16_-_48993931 1.830 ENSMUST00000114516.1
Dzip3
DAZ interacting protein 3, zinc finger
chr13_+_93304940 1.803 ENSMUST00000109497.1
ENSMUST00000109498.1
ENSMUST00000060490.4
ENSMUST00000109492.1
ENSMUST00000109496.1
ENSMUST00000109495.1
Homer1





homer homolog 1 (Drosophila)





chr16_+_17561885 1.802 ENSMUST00000171002.1
ENSMUST00000023441.4
P2rx6

purinergic receptor P2X, ligand-gated ion channel, 6

chr14_-_55560340 1.718 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr15_+_78899755 1.702 ENSMUST00000001226.3
ENSMUST00000061239.7
ENSMUST00000109698.2
Sh3bp1


SH3-domain binding protein 1


chr9_+_31280525 1.696 ENSMUST00000117389.1
Prdm10
PR domain containing 10
chr8_-_34965631 1.552 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr14_+_55560480 1.491 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr8_+_109868586 1.445 ENSMUST00000179721.1
ENSMUST00000034175.4
Phlpp2

PH domain and leucine rich repeat protein phosphatase 2

chr11_+_75532127 1.391 ENSMUST00000127226.1
Slc43a2
solute carrier family 43, member 2
chr14_+_111675113 1.348 ENSMUST00000042767.7
Slitrk5
SLIT and NTRK-like family, member 5
chr8_+_46492789 1.323 ENSMUST00000110371.1
Acsl1
acyl-CoA synthetase long-chain family member 1
chr9_+_66350465 1.278 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr11_-_71004387 1.219 ENSMUST00000124464.1
ENSMUST00000108527.1
Dhx33

DEAH (Asp-Glu-Ala-His) box polypeptide 33

chr1_-_153332724 1.213 ENSMUST00000027752.8
Lamc1
laminin, gamma 1
chr9_-_108190352 1.203 ENSMUST00000035208.7
Bsn
bassoon
chr11_+_72796164 1.181 ENSMUST00000172220.1
Zzef1
zinc finger, ZZ-type with EF hand domain 1
chr11_-_70687917 1.138 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
Camta2




calmodulin binding transcription activator 2




chr4_-_70534904 1.117 ENSMUST00000107359.2
Megf9
multiple EGF-like-domains 9
chr1_-_36445248 1.109 ENSMUST00000125304.1
ENSMUST00000115011.1
Lman2l

lectin, mannose-binding 2-like

chr13_+_93304799 1.099 ENSMUST00000080127.5
Homer1
homer homolog 1 (Drosophila)
chr8_+_72240052 1.099 ENSMUST00000145213.1
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr11_-_119547744 1.097 ENSMUST00000026670.4
Nptx1
neuronal pentraxin 1
chr5_-_148928619 1.079 ENSMUST00000149169.1
ENSMUST00000047257.8
Katnal1

katanin p60 subunit A-like 1

chr8_+_72240315 1.076 ENSMUST00000126885.1
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr15_-_100599983 1.068 ENSMUST00000073837.6
Pou6f1
POU domain, class 6, transcription factor 1
chr11_+_72796254 1.049 ENSMUST00000069395.5
Zzef1
zinc finger, ZZ-type with EF hand domain 1
chrX_-_7574120 1.047 ENSMUST00000045924.7
ENSMUST00000115742.2
ENSMUST00000150787.1
Ppp1r3f


protein phosphatase 1, regulatory (inhibitor) subunit 3F


chr8_-_122432924 1.045 ENSMUST00000017604.8
Cyba
cytochrome b-245, alpha polypeptide
chr12_+_8674391 1.029 ENSMUST00000163569.1
ENSMUST00000169089.1
Pum2

pumilio 2 (Drosophila)

chr11_+_75532099 0.982 ENSMUST00000169547.2
Slc43a2
solute carrier family 43, member 2
chr9_+_67840386 0.913 ENSMUST00000077879.5
Vps13c
vacuolar protein sorting 13C (yeast)
chr19_+_8617991 0.895 ENSMUST00000010250.2
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr11_+_53519920 0.889 ENSMUST00000147912.1
Sept8
septin 8
chr14_+_25607797 0.866 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr11_-_70688097 0.864 ENSMUST00000108544.1
Camta2
calmodulin binding transcription activator 2
chr19_-_41848076 0.852 ENSMUST00000059231.2
Frat2
frequently rearranged in advanced T cell lymphomas 2
chr14_+_55560904 0.833 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr10_+_93589413 0.784 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr11_+_120098910 0.770 ENSMUST00000106223.2
1810043H04Rik
RIKEN cDNA 1810043H04 gene
chr11_+_53519871 0.757 ENSMUST00000120878.2
Sept8
septin 8
chr16_-_48994081 0.747 ENSMUST00000121869.1
Dzip3
DAZ interacting protein 3, zinc finger
chr11_+_85832551 0.745 ENSMUST00000000095.6
Tbx2
T-box 2
chr5_+_115279666 0.743 ENSMUST00000040421.4
Coq5
coenzyme Q5 homolog, methyltransferase (yeast)
chr11_+_108921648 0.727 ENSMUST00000144511.1
Axin2
axin2
chr8_-_67515606 0.691 ENSMUST00000032981.5
Gm9755
predicted pseudogene 9755
chr7_-_19715395 0.691 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr16_+_44173239 0.669 ENSMUST00000119746.1
Gm608
predicted gene 608
chr18_-_20896078 0.664 ENSMUST00000025177.6
ENSMUST00000097658.1
Trappc8

trafficking protein particle complex 8

chrX_-_20291776 0.661 ENSMUST00000072451.4
Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr11_-_102447647 0.660 ENSMUST00000049057.4
Fam171a2
family with sequence similarity 171, member A2
chr8_+_25602236 0.656 ENSMUST00000146919.1
ENSMUST00000142395.1
ENSMUST00000139966.1
Whsc1l1


Wolf-Hirschhorn syndrome candidate 1-like 1 (human)


chr17_+_50509518 0.625 ENSMUST00000043938.6
Plcl2
phospholipase C-like 2
chr8_+_72240018 0.609 ENSMUST00000003117.8
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr1_+_136018062 0.608 ENSMUST00000117950.1
Tmem9
transmembrane protein 9
chr2_+_121956411 0.602 ENSMUST00000110578.1
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr4_+_42949814 0.591 ENSMUST00000037872.3
ENSMUST00000098112.2
Dnajb5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr17_-_29347902 0.571 ENSMUST00000095427.4
ENSMUST00000118366.1
Mtch1

mitochondrial carrier homolog 1 (C. elegans)

chr10_+_111164794 0.535 ENSMUST00000105275.1
ENSMUST00000095310.1
Osbpl8

oxysterol binding protein-like 8

chrX_-_41911877 0.530 ENSMUST00000047037.8
Thoc2
THO complex 2
chr12_+_29938036 0.527 ENSMUST00000122328.1
ENSMUST00000118321.1
Pxdn

peroxidasin homolog (Drosophila)

chr11_+_70562898 0.500 ENSMUST00000102559.4
Mink1
misshapen-like kinase 1 (zebrafish)
chr11_+_93996082 0.470 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr11_+_70562840 0.424 ENSMUST00000072237.6
ENSMUST00000072873.7
Mink1

misshapen-like kinase 1 (zebrafish)

chr7_-_98361275 0.420 ENSMUST00000094161.4
ENSMUST00000164726.1
ENSMUST00000167405.1
Tsku


tsukushi


chr10_-_79874211 0.415 ENSMUST00000167897.1
BC005764
cDNA sequence BC005764
chr7_-_98361310 0.411 ENSMUST00000165257.1
Tsku
tsukushi
chr19_+_40612392 0.403 ENSMUST00000134063.1
Entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr19_+_5038826 0.400 ENSMUST00000053705.6
B3gnt1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr12_-_76369385 0.395 ENSMUST00000176187.1
ENSMUST00000167011.1
ENSMUST00000176967.1
Zbtb25


zinc finger and BTB domain containing 25


chr14_+_55561060 0.392 ENSMUST00000117701.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr12_+_8674681 0.384 ENSMUST00000168361.1
ENSMUST00000169750.1
ENSMUST00000163730.1
Pum2


pumilio 2 (Drosophila)


chr9_+_100643605 0.377 ENSMUST00000041418.6
Stag1
stromal antigen 1
chr12_-_110840905 0.369 ENSMUST00000177224.1
ENSMUST00000084974.4
ENSMUST00000070565.8
Stk30


serine/threonine kinase 30


chr17_-_56716788 0.369 ENSMUST00000067931.5
Vmac
vimentin-type intermediate filament associated coiled-coil protein
chrX_-_48208566 0.365 ENSMUST00000037960.4
Zdhhc9
zinc finger, DHHC domain containing 9
chr7_-_6331235 0.344 ENSMUST00000127658.1
ENSMUST00000062765.7
Zfp583

zinc finger protein 583

chr11_-_100441795 0.333 ENSMUST00000107398.1
Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr12_+_31265279 0.324 ENSMUST00000002979.8
ENSMUST00000170495.1
Lamb1

laminin B1

chr7_+_80343091 0.307 ENSMUST00000032747.5
Hddc3
HD domain containing 3
chr6_-_134792596 0.290 ENSMUST00000100857.3
Dusp16
dual specificity phosphatase 16
chr11_+_53519725 0.278 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
Sept8


septin 8


chr11_+_70562980 0.261 ENSMUST00000079244.5
ENSMUST00000102558.4
Mink1

misshapen-like kinase 1 (zebrafish)

chr17_+_34894515 0.214 ENSMUST00000052778.8
Zbtb12
zinc finger and BTB domain containing 12
chr12_+_71831064 0.205 ENSMUST00000085299.2
Daam1
dishevelled associated activator of morphogenesis 1
chrX_-_20291728 0.198 ENSMUST00000115393.2
Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr12_-_76369586 0.196 ENSMUST00000176278.1
Zbtb25
zinc finger and BTB domain containing 25
chr11_-_72796028 0.174 ENSMUST00000156294.1
Cyb5d2
cytochrome b5 domain containing 2
chr12_+_31265234 0.171 ENSMUST00000169088.1
Lamb1
laminin B1
chr5_-_136883115 0.165 ENSMUST00000057497.6
ENSMUST00000111103.1
Col26a1

collagen, type XXVI, alpha 1

chrX_+_152233228 0.142 ENSMUST00000112588.2
ENSMUST00000082177.6
Kdm5c

lysine (K)-specific demethylase 5C

chr4_-_124850670 0.108 ENSMUST00000163946.1
ENSMUST00000106190.3
1110065P20Rik

RIKEN cDNA 1110065P20 gene

chr3_+_107036156 0.106 ENSMUST00000052718.3
Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr4_-_124850473 0.104 ENSMUST00000137769.2
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr10_-_93589621 0.086 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr7_-_44306903 0.079 ENSMUST00000004587.9
Clec11a
C-type lectin domain family 11, member a
chr2_+_121955964 0.070 ENSMUST00000036647.6
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr4_-_124851152 0.066 ENSMUST00000185036.1
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr2_+_158794807 0.031 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
Dhx35


DEAH (Asp-Glu-Ala-His) box polypeptide 35


chr12_-_4038905 0.011 ENSMUST00000111178.1
Efr3b
EFR3 homolog B (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 12.7 GO:1900034 regulation of cellular response to heat(GO:1900034)
1.2 3.5 GO:1902022 L-lysine transport(GO:1902022)
1.0 2.9 GO:0006566 threonine metabolic process(GO:0006566)
0.5 8.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.5 1.6 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.5 3.6 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.4 1.2 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.4 2.3 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.4 2.9 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.3 6.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.3 1.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 3.0 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 0.9 GO:0015747 urate transport(GO:0015747)
0.3 2.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 0.7 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.2 2.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.2 0.7 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.2 2.9 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.2 1.1 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.2 1.3 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.2 1.0 GO:0003105 negative regulation of glomerular filtration(GO:0003105) positive regulation of NAD(P)H oxidase activity(GO:0033864) positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.2 0.6 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2 0.8 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 3.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 2.8 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.2 1.9 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.2 1.1 GO:0051013 microtubule severing(GO:0051013)
0.2 0.5 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 1.9 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.9 GO:1901525 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734) negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.1 0.9 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.5 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 1.3 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 0.7 GO:0030242 pexophagy(GO:0030242)
0.1 1.0 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.1 2.0 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1 4.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 4.7 GO:0015807 L-amino acid transport(GO:0015807)
0.1 1.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.4 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.1 2.7 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 1.3 GO:0021756 striatum development(GO:0021756)
0.1 0.5 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 0.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 1.3 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 7.4 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 1.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.6 GO:0033198 response to ATP(GO:0033198)
0.0 2.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 2.8 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.5 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.7 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 2.6 GO:0007411 axon guidance(GO:0007411)
0.0 2.9 GO:0007409 axonogenesis(GO:0007409)
0.0 10.3 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.6 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 6.9 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
1.3 12.7 GO:0045298 tubulin complex(GO:0045298)
0.7 6.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 2.7 GO:0008091 spectrin(GO:0008091)
0.4 1.7 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.4 2.1 GO:0001533 cornified envelope(GO:0001533)
0.4 1.2 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.3 2.6 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 1.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 2.9 GO:0035253 ciliary rootlet(GO:0035253)
0.1 4.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.4 GO:0045098 type III intermediate filament(GO:0045098)
0.1 1.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 8.2 GO:0030118 clathrin coat(GO:0030118)
0.1 2.4 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 2.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 2.9 GO:0043034 costamere(GO:0043034)
0.1 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 8.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.4 GO:0005605 basal lamina(GO:0005605)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0 1.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 12.7 GO:0099609 microtubule lateral binding(GO:0099609)
1.0 2.9 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.9 3.5 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.7 8.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.6 1.9 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.4 1.3 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.3 2.9 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.3 1.0 GO:2001069 glycogen binding(GO:2001069)
0.3 1.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.3 9.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 0.9 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 1.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 2.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 3.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 2.7 GO:0030506 ankyrin binding(GO:0030506)
0.1 4.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 1.2 GO:0000182 rDNA binding(GO:0000182)
0.1 0.7 GO:0015288 porin activity(GO:0015288)
0.1 0.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.9 GO:0008483 transaminase activity(GO:0008483)
0.1 1.2 GO:0045503 dynein light chain binding(GO:0045503)
0.1 1.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 5.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 1.9 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 8.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 2.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 4.3 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 0.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 3.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 6.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 2.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 3.3 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.4 GO:0044325 ion channel binding(GO:0044325)
0.0 1.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.9 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 12.7 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 11.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.2 8.5 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 4.7 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 2.8 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.8 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 12.7 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4 3.0 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.4 5.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 8.1 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 4.3 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 8.5 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.1 0.9 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 6.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 5.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.9 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.9 REACTOME_KINESINS Genes involved in Kinesins
0.1 2.7 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH Genes involved in NCAM signaling for neurite out-growth
0.1 1.3 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.9 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.0 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 2.5 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.7 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.9 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides