Motif ID: Zfp105

Z-value: 0.690


Transcription factors associated with Zfp105:

Gene SymbolEntrez IDGene Name
Zfp105 ENSMUSG00000057895.5 Zfp105

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp105mm10_v2_chr9_+_122923050_1229230990.694.0e-12Click!


Activity profile for motif Zfp105.

activity profile for motif Zfp105


Sorted Z-values histogram for motif Zfp105

Sorted Z-values for motif Zfp105



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp105

PNG image of the network

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Top targets:


Showing 1 to 20 of 45 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_144892813 10.995 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr5_+_17574268 9.612 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr1_-_190170671 7.859 ENSMUST00000175916.1
 Prox1
prospero-related homeobox 1
chr2_-_91931774 6.531 ENSMUST00000069423.6
 Mdk
midkine
chr8_+_128359065 6.080 ENSMUST00000026917.8
 Nrp1
neuropilin 1
chr5_-_111761697 5.938 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
 E130006D01Rik


RIKEN cDNA E130006D01 gene


chr6_-_127151044 5.267 ENSMUST00000000188.8
 Ccnd2
cyclin D2
chr5_+_13399309 5.213 ENSMUST00000030714.7
ENSMUST00000141968.1
 Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

chr4_+_11704439 4.835 ENSMUST00000108304.2
 Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr18_+_69344503 3.025 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr9_-_78378725 2.994 ENSMUST00000034900.7
 Ooep
oocyte expressed protein
chr11_-_101466222 2.886 ENSMUST00000040430.7
 Vat1
vesicle amine transport protein 1 homolog (T californica)
chr18_+_35829798 2.867 ENSMUST00000060722.6
 Cxxc5
CXXC finger 5
chr12_-_90738438 2.562 ENSMUST00000082432.3
 Dio2
deiodinase, iodothyronine, type II
chr9_+_58134535 2.277 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
 Stra6



stimulated by retinoic acid gene 6



chr8_-_11008458 2.264 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr8_-_84773381 2.004 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr11_-_100411874 1.643 ENSMUST00000141840.1
 Leprel4
leprecan-like 4
chr2_-_177267036 1.509 ENSMUST00000108963.1
 Gm14409
predicted gene 14409
chr8_-_64205970 1.457 ENSMUST00000066166.4
 Tll1
tolloid-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.0 20.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
1.0 11.0 GO:0042572 retinol metabolic process(GO:0042572)
2.6 7.9 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
2.2 6.5 GO:0030421 defecation(GO:0030421)
0.4 5.3 GO:0071481 cellular response to X-ray(GO:0071481)
0.5 4.8 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.3 3.0 GO:0042118 endothelial cell activation(GO:0042118)
0.1 3.0 GO:0007566 embryo implantation(GO:0007566)
0.6 2.9 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 2.9 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.5 2.6 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.5 2.3 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.2 2.3 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 2.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.4 1.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.3 0.9 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.1 0.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.6 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)

Gene overrepresentation in cellular_component category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.5 GO:0005615 extracellular space(GO:0005615)
1.0 6.1 GO:0097443 sorting endosome(GO:0097443)
1.3 5.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 4.8 GO:0051233 spindle midzone(GO:0051233)
0.0 3.2 GO:0005938 cell cortex(GO:0005938)
0.0 3.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.0 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.9 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 14.8 GO:0038191 neuropilin binding(GO:0038191)
1.6 11.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.7 7.9 GO:0050693 LBD domain binding(GO:0050693)
0.1 6.5 GO:0008083 growth factor activity(GO:0008083)
1.2 6.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 4.8 GO:0019003 GDP binding(GO:0019003)
0.8 3.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 2.3 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 2.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.5 GO:0005518 collagen binding(GO:0005518)
0.1 0.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.6 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.6 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)

Gene overrepresentation in C2:CP category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 14.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 11.0 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 6.5 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.5 6.1 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 5.3 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 3.0 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 2.3 PID_EPO_PATHWAY EPO signaling pathway
0.0 1.5 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.2 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 11.3 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 5.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 3.0 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.2 2.6 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 2.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 1.5 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.4 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination