Motif ID: Zfp128

Z-value: 0.282


Transcription factors associated with Zfp128:

Gene SymbolEntrez IDGene Name
Zfp128 ENSMUSG00000060397.6 Zfp128

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp128mm10_v2_chr7_+_12881165_128812040.122.9e-01Click!


Activity profile for motif Zfp128.

activity profile for motif Zfp128


Sorted Z-values histogram for motif Zfp128

Sorted Z-values for motif Zfp128



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp128

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_45975224 2.543 ENSMUST00000095323.1
ENSMUST00000098786.2
1700029J07Rik

RIKEN cDNA 1700029J07 gene

chr7_-_79386943 1.946 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr1_-_195092242 1.867 ENSMUST00000162650.1
ENSMUST00000160817.1
ENSMUST00000162614.1
ENSMUST00000016637.6
Cd46



CD46 antigen, complement regulatory protein



chr15_-_84065329 1.781 ENSMUST00000156187.1
Efcab6
EF-hand calcium binding domain 6
chr1_-_190170671 1.746 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr5_-_147725988 1.218 ENSMUST00000110529.1
ENSMUST00000031652.3
ENSMUST00000031653.5
Flt1


FMS-like tyrosine kinase 1


chr7_+_45526330 1.082 ENSMUST00000120985.1
ENSMUST00000051810.8
Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr10_-_53647080 0.751 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr15_+_76246747 0.592 ENSMUST00000023225.6
Grina
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr14_-_105896819 0.576 ENSMUST00000022709.4
Spry2
sprouty homolog 2 (Drosophila)
chr7_+_24112314 0.529 ENSMUST00000120006.1
ENSMUST00000005413.3
Zfp112

zinc finger protein 112

chr11_+_32300069 0.441 ENSMUST00000020535.1
Hbq1a
hemoglobin, theta 1A
chr6_-_118562226 0.435 ENSMUST00000112830.1
Ankrd26
ankyrin repeat domain 26
chr18_+_74065102 0.430 ENSMUST00000066583.1
Gm9925
predicted gene 9925
chr6_+_17281185 0.413 ENSMUST00000000058.6
Cav2
caveolin 2
chr13_-_66933080 0.410 ENSMUST00000021991.4
Mterfd1
MTERF domain containing 1
chr3_+_146220955 0.405 ENSMUST00000039164.2
Lpar3
lysophosphatidic acid receptor 3
chr6_+_145211134 0.400 ENSMUST00000111725.1
ENSMUST00000111726.3
ENSMUST00000039729.3
ENSMUST00000111723.1
ENSMUST00000111724.1
ENSMUST00000111721.1
ENSMUST00000111719.1
Lyrm5






LYR motif containing 5






chr2_-_30124529 0.359 ENSMUST00000113677.1
Zer1
zyg-11 related, cell cycle regulator
chr12_+_51593315 0.357 ENSMUST00000164782.2
ENSMUST00000085412.5
Coch

coagulation factor C homolog (Limulus polyphemus)

chr13_-_66932904 0.348 ENSMUST00000172597.1
Mterfd1
MTERF domain containing 1
chr2_+_5137756 0.335 ENSMUST00000027988.7
Ccdc3
coiled-coil domain containing 3
chr8_-_126945841 0.331 ENSMUST00000179857.1
Tomm20
translocase of outer mitochondrial membrane 20 homolog (yeast)
chr13_-_66933014 0.330 ENSMUST00000173773.1
Mterfd1
MTERF domain containing 1
chr2_-_30124454 0.321 ENSMUST00000044751.8
Zer1
zyg-11 related, cell cycle regulator
chr18_+_56432116 0.319 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr9_-_59353430 0.294 ENSMUST00000026265.6
Bbs4
Bardet-Biedl syndrome 4 (human)
chr16_-_14159232 0.247 ENSMUST00000090300.4
Marf1
meiosis arrest female 1
chr2_+_71055731 0.246 ENSMUST00000154704.1
ENSMUST00000135357.1
ENSMUST00000064141.5
ENSMUST00000112159.2
ENSMUST00000102701.3
Dcaf17




DDB1 and CUL4 associated factor 17




chr9_+_3335470 0.240 ENSMUST00000053407.5
Alkbh8
alkB, alkylation repair homolog 8 (E. coli)
chr17_-_26244118 0.221 ENSMUST00000118487.1
Itfg3
integrin alpha FG-GAP repeat containing 3
chr17_-_26244203 0.218 ENSMUST00000114988.1
Itfg3
integrin alpha FG-GAP repeat containing 3
chr15_+_41788979 0.184 ENSMUST00000170127.1
Oxr1
oxidation resistance 1
chr8_-_41133697 0.148 ENSMUST00000155055.1
ENSMUST00000059115.6
ENSMUST00000145860.1
Mtus1


mitochondrial tumor suppressor 1


chr14_+_54894133 0.144 ENSMUST00000116476.2
ENSMUST00000022808.7
ENSMUST00000150975.1
Pabpn1


poly(A) binding protein, nuclear 1


chr9_+_21411824 0.143 ENSMUST00000002902.6
Qtrt1
queuine tRNA-ribosyltransferase 1
chr8_+_45975514 0.136 ENSMUST00000034051.6
Ufsp2
UFM1-specific peptidase 2
chr7_-_44929410 0.116 ENSMUST00000107857.3
ENSMUST00000085399.6
ENSMUST00000167930.1
ENSMUST00000166972.1
Ap2a1



adaptor-related protein complex 2, alpha 1 subunit



chr13_-_59769751 0.112 ENSMUST00000057115.6
Isca1
iron-sulfur cluster assembly 1 homolog (S. cerevisiae)
chr4_+_15881255 0.087 ENSMUST00000029876.1
Calb1
calbindin 1
chr6_-_113501818 0.086 ENSMUST00000101059.1
Prrt3
proline-rich transmembrane protein 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0043379 memory T cell differentiation(GO:0043379)
0.6 1.7 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.2 1.2 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.6 GO:0060437 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) lung growth(GO:0060437)
0.1 0.3 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 0.3 GO:1903546 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.4 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.1 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.3 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.6 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 1.8 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.4 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.7 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.7 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0034464 BBSome(GO:0034464)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0019841 retinol binding(GO:0019841)
0.2 1.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 1.9 GO:0001848 complement binding(GO:0001848)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 1.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling