Motif ID: Zfp219_Zfp740

Z-value: 1.123

Transcription factors associated with Zfp219_Zfp740:

Gene SymbolEntrez IDGene Name
Zfp219 ENSMUSG00000049295.10 Zfp219
Zfp740 ENSMUSG00000046897.10 Zfp740

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp219mm10_v2_chr14_-_52020698_520207370.161.8e-01Click!
Zfp740mm10_v2_chr15_+_102203639_1022037090.019.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp219_Zfp740

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_44173271 8.679 ENSMUST00000088356.4
ENSMUST00000169582.1
Gm608

predicted gene 608

chr5_-_134747241 8.446 ENSMUST00000015138.9
Eln
elastin
chr7_-_78577771 8.402 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr7_-_78578308 8.109 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr15_+_57694651 8.008 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chr1_-_56972437 7.348 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr16_+_44173239 7.077 ENSMUST00000119746.1
Gm608
predicted gene 608
chr16_+_43503607 6.844 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr2_-_116065798 6.607 ENSMUST00000110907.1
ENSMUST00000110908.2
Meis2

Meis homeobox 2

chr4_-_88033328 6.487 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr12_-_27342696 6.386 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr2_+_48949495 5.529 ENSMUST00000112745.1
Mbd5
methyl-CpG binding domain protein 5
chr2_-_180225812 5.487 ENSMUST00000015791.5
Lama5
laminin, alpha 5
chr3_+_28263563 4.807 ENSMUST00000160307.2
ENSMUST00000159680.2
ENSMUST00000160518.1
ENSMUST00000162485.1
ENSMUST00000159308.1
ENSMUST00000162777.1
ENSMUST00000161964.1
Tnik






TRAF2 and NCK interacting kinase






chr14_+_21500879 4.618 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr6_+_4903350 4.603 ENSMUST00000175962.1
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr17_+_75005523 4.537 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chrX_-_94123087 4.425 ENSMUST00000113925.1
Zfx
zinc finger protein X-linked
chr10_-_127341583 4.361 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chr4_+_144892813 4.351 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chrX_-_38564519 4.206 ENSMUST00000016681.8
Cul4b
cullin 4B
chr18_+_69346143 4.168 ENSMUST00000114980.1
Tcf4
transcription factor 4
chrX_-_104201126 4.130 ENSMUST00000056502.6
ENSMUST00000118314.1
C77370

expressed sequence C77370

chr18_+_69345721 4.064 ENSMUST00000078486.6
ENSMUST00000114982.1
Tcf4

transcription factor 4

chr11_-_69369377 3.953 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr13_-_29984219 3.843 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr3_-_89393294 3.772 ENSMUST00000142119.1
ENSMUST00000029677.8
ENSMUST00000148361.1
Zbtb7b


zinc finger and BTB domain containing 7B


chr2_-_45113255 3.712 ENSMUST00000068415.4
ENSMUST00000127520.1
Zeb2

zinc finger E-box binding homeobox 2

chr12_-_118301429 3.678 ENSMUST00000026367.9
Sp4
trans-acting transcription factor 4
chr10_-_127620922 3.657 ENSMUST00000118455.1
Lrp1
low density lipoprotein receptor-related protein 1
chr5_+_64803513 3.635 ENSMUST00000165536.1
Klf3
Kruppel-like factor 3 (basic)
chr2_-_119477613 3.629 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr7_+_97579868 3.567 ENSMUST00000042399.7
ENSMUST00000107153.1
Rsf1

remodeling and spacing factor 1

chr4_+_144893077 3.551 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr1_-_168431695 3.513 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr6_+_4903298 3.502 ENSMUST00000035813.2
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr3_+_28263205 3.475 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr7_+_122289297 3.438 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr1_-_64121389 3.364 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr6_-_28261907 3.306 ENSMUST00000115320.1
ENSMUST00000123098.1
ENSMUST00000115321.2
ENSMUST00000155494.1
Zfp800



zinc finger protein 800



chr9_-_44881274 3.265 ENSMUST00000002095.3
ENSMUST00000114689.1
ENSMUST00000128768.1
Kmt2a


lysine (K)-specific methyltransferase 2A


chr2_-_45113216 3.253 ENSMUST00000124942.1
Zeb2
zinc finger E-box binding homeobox 2
chr10_+_127705170 3.239 ENSMUST00000079590.5
Myo1a
myosin IA
chr2_-_120850364 3.230 ENSMUST00000131389.1
Ttbk2
tau tubulin kinase 2
chr11_+_69765970 3.128 ENSMUST00000108642.1
ENSMUST00000156932.1
Zbtb4

zinc finger and BTB domain containing 4

chr11_-_69801716 3.062 ENSMUST00000011285.4
ENSMUST00000102585.1
Fgf11

fibroblast growth factor 11

chr1_-_168431896 3.058 ENSMUST00000176540.1
Pbx1
pre B cell leukemia homeobox 1
chr1_-_119422239 3.047 ENSMUST00000038765.5
Inhbb
inhibin beta-B
chr2_+_128126030 3.003 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr10_-_127620960 2.974 ENSMUST00000121829.1
Lrp1
low density lipoprotein receptor-related protein 1
chr2_-_31141802 2.966 ENSMUST00000073879.5
ENSMUST00000100208.2
ENSMUST00000100207.2
ENSMUST00000113555.1
ENSMUST00000075326.4
ENSMUST00000113552.2
ENSMUST00000136181.1
Fnbp1






formin binding protein 1






chr4_+_32615473 2.806 ENSMUST00000178925.1
ENSMUST00000029950.3
Casp8ap2

caspase 8 associated protein 2

chr4_-_151861667 2.786 ENSMUST00000169423.2
Camta1
calmodulin binding transcription activator 1
chr2_-_29253001 2.779 ENSMUST00000071201.4
Ntng2
netrin G2
chr3_+_41564880 2.714 ENSMUST00000168086.1
Phf17
PHD finger protein 17
chr4_-_154636831 2.683 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr1_-_56969864 2.663 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr2_-_161109017 2.582 ENSMUST00000039782.7
ENSMUST00000134178.1
Chd6

chromodomain helicase DNA binding protein 6

chr2_-_120850389 2.546 ENSMUST00000143051.1
ENSMUST00000057135.7
ENSMUST00000085840.4
Ttbk2


tau tubulin kinase 2


chr2_-_116065047 2.538 ENSMUST00000028639.6
ENSMUST00000102538.4
Meis2

Meis homeobox 2

chr9_+_44499126 2.510 ENSMUST00000074989.5
Bcl9l
B cell CLL/lymphoma 9-like
chr14_-_54781886 2.508 ENSMUST00000022787.6
Slc7a8
solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
chr4_-_151861762 2.489 ENSMUST00000097774.2
Camta1
calmodulin binding transcription activator 1
chr16_-_4213404 2.477 ENSMUST00000023165.6
Crebbp
CREB binding protein
chr12_+_102949450 2.474 ENSMUST00000179002.1
Unc79
unc-79 homolog (C. elegans)
chr7_+_127511976 2.464 ENSMUST00000098025.4
Srcap
Snf2-related CREBBP activator protein
chr18_+_64340225 2.441 ENSMUST00000175965.2
ENSMUST00000115145.3
Onecut2

one cut domain, family member 2

chr5_+_19227046 2.423 ENSMUST00000088516.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr15_-_50890041 2.401 ENSMUST00000077935.5
Trps1
trichorhinophalangeal syndrome I (human)
chr12_-_31950210 2.400 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
Hbp1


high mobility group box transcription factor 1


chr4_-_151861698 2.375 ENSMUST00000049790.7
Camta1
calmodulin binding transcription activator 1
chr5_-_25498748 2.373 ENSMUST00000173174.1
Kmt2c
lysine (K)-specific methyltransferase 2C
chr2_-_146511899 2.370 ENSMUST00000131824.1
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chrY_+_897782 2.364 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr8_-_11008458 2.350 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr8_-_31918203 2.349 ENSMUST00000073884.4
Nrg1
neuregulin 1
chr17_+_78200240 2.344 ENSMUST00000112498.2
Crim1
cysteine rich transmembrane BMP regulator 1 (chordin like)
chr11_-_88718165 2.342 ENSMUST00000107908.1
Msi2
musashi RNA-binding protein 2
chr4_-_3938354 2.330 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chrX_+_9199865 2.294 ENSMUST00000069763.2
Lancl3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr12_-_31950170 2.285 ENSMUST00000176520.1
Hbp1
high mobility group box transcription factor 1
chr1_-_56971762 2.239 ENSMUST00000114415.3
Satb2
special AT-rich sequence binding protein 2
chr15_+_102406143 2.237 ENSMUST00000170884.1
ENSMUST00000165924.1
ENSMUST00000163709.1
ENSMUST00000001326.6
Sp1



trans-acting transcription factor 1



chrX_+_42149534 2.210 ENSMUST00000127618.1
Stag2
stromal antigen 2
chr2_-_120850598 2.180 ENSMUST00000028740.4
Ttbk2
tau tubulin kinase 2
chr1_+_59764264 2.179 ENSMUST00000087435.5
Bmpr2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr1_-_56969827 2.173 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr11_+_23306884 2.161 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr2_-_45112890 2.147 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chrX_-_160994665 2.142 ENSMUST00000087104.4
Cdkl5
cyclin-dependent kinase-like 5
chr7_+_25282784 2.136 ENSMUST00000165239.1
Cic
capicua homolog (Drosophila)
chr5_-_25498702 2.097 ENSMUST00000173073.1
ENSMUST00000045291.7
Kmt2c

lysine (K)-specific methyltransferase 2C

chr12_-_75177325 2.088 ENSMUST00000042299.2
Kcnh5
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr15_-_8444449 2.073 ENSMUST00000052965.6
Nipbl
Nipped-B homolog (Drosophila)
chr14_+_116925379 1.987 ENSMUST00000088483.3
Gpc6
glypican 6
chr14_+_116925516 1.979 ENSMUST00000125435.1
Gpc6
glypican 6
chrX_-_94123359 1.966 ENSMUST00000137853.1
ENSMUST00000088102.5
ENSMUST00000113927.1
Zfx


zinc finger protein X-linked


chr5_-_3803081 1.966 ENSMUST00000043551.6
Ankib1
ankyrin repeat and IBR domain containing 1
chr10_-_23349887 1.952 ENSMUST00000074366.6
ENSMUST00000092665.4
Eya4

eyes absent 4 homolog (Drosophila)

chr10_+_106470281 1.927 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr1_-_168431502 1.919 ENSMUST00000064438.4
Pbx1
pre B cell leukemia homeobox 1
chr14_-_51913393 1.835 ENSMUST00000004673.7
ENSMUST00000111632.3
Ndrg2

N-myc downstream regulated gene 2

chr11_+_69765899 1.818 ENSMUST00000108640.1
ENSMUST00000108639.1
Zbtb4

zinc finger and BTB domain containing 4

chr18_+_49832622 1.815 ENSMUST00000180611.1
Dmxl1
Dmx-like 1
chr7_+_127777095 1.812 ENSMUST00000144406.1
Setd1a
SET domain containing 1A
chr2_+_153031852 1.809 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr4_+_108460000 1.802 ENSMUST00000097925.2
Zcchc11
zinc finger, CCHC domain containing 11
chr4_+_137993445 1.794 ENSMUST00000105831.2
ENSMUST00000084214.5
Eif4g3

eukaryotic translation initiation factor 4 gamma, 3

chr11_+_23256001 1.791 ENSMUST00000020538.6
ENSMUST00000109551.1
ENSMUST00000102870.1
ENSMUST00000102869.1
Xpo1



exportin 1, CRM1 homolog (yeast)



chr10_-_7956223 1.783 ENSMUST00000146444.1
Tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr2_+_18064645 1.782 ENSMUST00000114680.2
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr2_-_146511992 1.773 ENSMUST00000109986.2
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr11_-_88718078 1.764 ENSMUST00000092794.5
Msi2
musashi RNA-binding protein 2
chr2_+_49451486 1.763 ENSMUST00000092123.4
Epc2
enhancer of polycomb homolog 2 (Drosophila)
chr10_+_13966268 1.754 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr5_-_106696819 1.746 ENSMUST00000127434.1
ENSMUST00000112696.1
ENSMUST00000112698.1
Zfp644


zinc finger protein 644


chr14_+_116925291 1.722 ENSMUST00000078849.4
Gpc6
glypican 6
chr11_+_98203314 1.709 ENSMUST00000003203.7
ENSMUST00000107538.1
Cdk12

cyclin-dependent kinase 12

chrX_-_105928547 1.699 ENSMUST00000101305.2
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr4_+_119539716 1.676 ENSMUST00000137560.1
Foxj3
forkhead box J3
chr11_-_69605829 1.662 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr9_+_14276301 1.643 ENSMUST00000034507.7
Sesn3
sestrin 3
chr6_+_29433248 1.642 ENSMUST00000101617.2
ENSMUST00000065090.5
Flnc

filamin C, gamma

chr18_-_39490649 1.631 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr6_-_136173492 1.630 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr2_-_162661075 1.618 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
Ptprt



protein tyrosine phosphatase, receptor type, T



chr3_-_95217741 1.608 ENSMUST00000107204.1
Gabpb2
GA repeat binding protein, beta 2
chr18_+_34777008 1.594 ENSMUST00000043775.7
Kdm3b
KDM3B lysine (K)-specific demethylase 3B
chr5_+_137350371 1.588 ENSMUST00000166239.1
ENSMUST00000111054.1
Ephb4

Eph receptor B4

chr9_+_100643755 1.586 ENSMUST00000133388.1
Stag1
stromal antigen 1
chr11_-_88718223 1.584 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr11_-_97187872 1.578 ENSMUST00000001479.4
Kpnb1
karyopherin (importin) beta 1
chr1_-_189343704 1.577 ENSMUST00000180044.1
ENSMUST00000110920.1
Kcnk2

potassium channel, subfamily K, member 2

chr3_-_95217690 1.574 ENSMUST00000107209.1
Gabpb2
GA repeat binding protein, beta 2
chr13_-_101768154 1.572 ENSMUST00000055518.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chrX_-_36645359 1.562 ENSMUST00000051906.6
Akap17b
A kinase (PRKA) anchor protein 17B
chr15_-_100599864 1.557 ENSMUST00000177247.2
ENSMUST00000177505.2
Pou6f1

POU domain, class 6, transcription factor 1

chrX_-_47892396 1.544 ENSMUST00000153548.2
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr3_+_129532386 1.541 ENSMUST00000071402.2
Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr1_-_191397026 1.538 ENSMUST00000067976.3
Ppp2r5a
protein phosphatase 2, regulatory subunit B (B56), alpha isoform
chr4_+_97777780 1.536 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr11_+_84179852 1.535 ENSMUST00000136463.2
Acaca
acetyl-Coenzyme A carboxylase alpha
chr9_+_31280525 1.519 ENSMUST00000117389.1
Prdm10
PR domain containing 10
chrX_+_101254528 1.514 ENSMUST00000062000.4
Foxo4
forkhead box O4
chr9_+_72532609 1.512 ENSMUST00000183372.1
ENSMUST00000184015.1
Rfx7

regulatory factor X, 7

chr13_-_105054895 1.490 ENSMUST00000063551.5
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr13_+_111686303 1.479 ENSMUST00000047412.4
ENSMUST00000109271.2
Mier3

mesoderm induction early response 1, family member 3

chr15_-_36608959 1.478 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr5_+_137350101 1.474 ENSMUST00000061244.8
Ephb4
Eph receptor B4
chr5_-_106696530 1.474 ENSMUST00000137285.1
ENSMUST00000124263.1
ENSMUST00000112695.1
ENSMUST00000155495.1
ENSMUST00000135108.1
Zfp644




zinc finger protein 644




chrX_+_151803642 1.472 ENSMUST00000156616.2
Huwe1
HECT, UBA and WWE domain containing 1
chr3_-_95217877 1.466 ENSMUST00000136139.1
Gabpb2
GA repeat binding protein, beta 2
chr4_-_24430838 1.460 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr8_+_22859528 1.454 ENSMUST00000110696.1
ENSMUST00000044331.6
Kat6a

K(lysine) acetyltransferase 6A

chr7_+_28180226 1.443 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr7_+_28180272 1.442 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr1_-_189343342 1.420 ENSMUST00000079451.6
Kcnk2
potassium channel, subfamily K, member 2
chr8_+_45885479 1.418 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr3_+_52268337 1.415 ENSMUST00000053764.5
Foxo1
forkhead box O1
chr2_+_57237651 1.415 ENSMUST00000169687.1
Gpd2
glycerol phosphate dehydrogenase 2, mitochondrial
chr18_-_72351009 1.401 ENSMUST00000073379.5
Dcc
deleted in colorectal carcinoma
chr15_-_50889691 1.394 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr17_-_28350747 1.391 ENSMUST00000080572.7
ENSMUST00000156862.1
Tead3

TEA domain family member 3

chr6_-_120038647 1.386 ENSMUST00000088646.5
ENSMUST00000177761.1
ENSMUST00000088644.6
ENSMUST00000060043.6
Wnk1



WNK lysine deficient protein kinase 1



chr5_+_65764073 1.383 ENSMUST00000138239.1
ENSMUST00000087264.3
N4bp2

NEDD4 binding protein 2

chr9_-_59036387 1.375 ENSMUST00000068664.5
Neo1
neogenin
chr5_+_118560719 1.348 ENSMUST00000100816.4
Med13l
mediator complex subunit 13-like
chr11_+_23306910 1.343 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr10_+_79854618 1.342 ENSMUST00000165704.1
Ptbp1
polypyrimidine tract binding protein 1
chr17_-_51826562 1.341 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chrX_+_42149288 1.338 ENSMUST00000115073.2
ENSMUST00000115072.1
Stag2

stromal antigen 2

chr5_+_137350162 1.329 ENSMUST00000111055.2
Ephb4
Eph receptor B4
chr4_-_118179946 1.319 ENSMUST00000050288.8
ENSMUST00000106403.1
Kdm4a

lysine (K)-specific demethylase 4A

chr19_-_3686549 1.310 ENSMUST00000025856.10
ENSMUST00000176867.1
Lrp5

low density lipoprotein receptor-related protein 5

chr18_-_72351029 1.307 ENSMUST00000114943.3
Dcc
deleted in colorectal carcinoma
chr14_-_118925314 1.304 ENSMUST00000004055.8
Dzip1
DAZ interacting protein 1
chr11_-_86357570 1.277 ENSMUST00000043624.8
Med13
mediator complex subunit 13
chrX_-_135009185 1.274 ENSMUST00000113185.2
ENSMUST00000064659.5
Zmat1

zinc finger, matrin type 1

chr9_+_69397933 1.266 ENSMUST00000117610.1
ENSMUST00000145538.1
ENSMUST00000117246.1
Narg2


NMDA receptor-regulated gene 2


chr11_+_23256566 1.242 ENSMUST00000136235.1
Xpo1
exportin 1, CRM1 homolog (yeast)
chr7_-_25132473 1.240 ENSMUST00000108418.4
ENSMUST00000108415.3
ENSMUST00000098679.3
ENSMUST00000175774.2
ENSMUST00000108417.3
ENSMUST00000108416.3
ENSMUST00000108414.1
ENSMUST00000108413.1
ENSMUST00000176408.1
Pou2f2








POU domain, class 2, transcription factor 2








chr5_-_19226555 1.236 ENSMUST00000180594.1
4921504A21Rik
RIKEN cDNA 4921504A21 gene
chr10_-_127666598 1.233 ENSMUST00000099157.3
Nab2
Ngfi-A binding protein 2
chr10_+_79854658 1.231 ENSMUST00000171599.1
ENSMUST00000095457.4
Ptbp1

polypyrimidine tract binding protein 1

chr9_+_69397897 1.228 ENSMUST00000034761.8
ENSMUST00000125938.1
Narg2

NMDA receptor-regulated gene 2

chrX_+_13071470 1.224 ENSMUST00000169594.2
Usp9x
ubiquitin specific peptidase 9, X chromosome
chr7_+_30291941 1.213 ENSMUST00000144508.1
Clip3
CAP-GLY domain containing linker protein 3
chr19_-_4397052 1.211 ENSMUST00000075856.4
Kdm2a
lysine (K)-specific demethylase 2A
chr11_+_79339792 1.210 ENSMUST00000108251.2
ENSMUST00000071325.2
Nf1

neurofibromatosis 1

chr11_-_6065538 1.209 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr9_-_82975475 1.206 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr19_-_28010995 1.199 ENSMUST00000172907.1
ENSMUST00000046898.9
Rfx3

regulatory factor X, 3 (influences HLA class II expression)

chr6_+_92091378 1.184 ENSMUST00000113460.1
Nr2c2
nuclear receptor subfamily 2, group C, member 2
chr2_+_84734050 1.177 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr1_-_64121456 1.173 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr2_+_18064564 1.170 ENSMUST00000114671.1
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr7_-_80405425 1.163 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)

chr14_-_56811716 1.149 ENSMUST00000039812.9
ENSMUST00000111285.2
Zmym5

zinc finger, MYM-type 5

chr11_+_54438188 1.144 ENSMUST00000046835.7
Fnip1
folliculin interacting protein 1
chrX_-_20291728 1.143 ENSMUST00000115393.2
Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.5 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
2.7 8.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
2.1 6.4 GO:0060023 soft palate development(GO:0060023)
1.8 5.5 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
1.8 7.3 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
1.7 10.1 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
1.7 8.3 GO:0007256 activation of JNKK activity(GO:0007256)
1.1 4.4 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.1 4.4 GO:0060032 notochord regression(GO:0060032)
1.1 2.2 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
1.0 3.0 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
1.0 3.0 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
1.0 4.0 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.9 2.7 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.8 4.1 GO:0060178 regulation of exocyst localization(GO:0060178)
0.8 8.2 GO:0042118 endothelial cell activation(GO:0042118)
0.8 3.8 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.8 3.0 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.7 11.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.7 7.7 GO:0042572 retinol metabolic process(GO:0042572)
0.7 4.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.7 3.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.6 2.6 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.6 3.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.6 1.8 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.6 1.2 GO:2000078 positive regulation of type B pancreatic cell development(GO:2000078)
0.6 2.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.6 7.8 GO:0070914 UV-damage excision repair(GO:0070914)
0.6 1.7 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.5 1.6 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.5 3.8 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.5 4.7 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.5 2.1 GO:0061010 gall bladder development(GO:0061010)
0.5 4.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.5 3.6 GO:0016584 nucleosome positioning(GO:0016584)
0.5 5.0 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.5 8.0 GO:1990403 embryonic brain development(GO:1990403)
0.5 2.8 GO:0036337 Fas signaling pathway(GO:0036337)
0.5 1.4 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.4 1.3 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.4 3.0 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.4 1.7 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.4 7.2 GO:0007379 segment specification(GO:0007379)
0.4 0.8 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209) fear response(GO:0042596)
0.4 1.6 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.4 1.2 GO:0032430 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.4 1.6 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.4 3.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.4 1.5 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.4 3.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.4 1.5 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.4 1.4 GO:0003192 mitral valve formation(GO:0003192) condensed mesenchymal cell proliferation(GO:0072137)
0.3 2.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.3 1.6 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.3 8.5 GO:0030325 adrenal gland development(GO:0030325)
0.3 2.0 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.3 3.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.3 2.9 GO:0048149 behavioral response to ethanol(GO:0048149)
0.3 2.2 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.3 0.9 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
0.3 1.5 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 1.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.3 1.2 GO:0090472 dibasic protein processing(GO:0090472)
0.3 0.9 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.3 0.9 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.3 1.1 GO:0015744 succinate transport(GO:0015744)
0.3 2.0 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.3 1.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.3 0.8 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 4.4 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.3 1.6 GO:0072718 response to cisplatin(GO:0072718)
0.2 2.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 1.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.2 2.4 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.2 1.9 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 2.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 0.9 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 1.7 GO:0002902 regulation of B cell apoptotic process(GO:0002902)
0.2 0.8 GO:0097494 regulation of vesicle size(GO:0097494)
0.2 1.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 1.8 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 3.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.2 0.6 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.2 1.4 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.2 1.0 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.2 1.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 1.5 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.2 1.9 GO:0071455 cellular response to hyperoxia(GO:0071455)
0.2 0.6 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.2 1.6 GO:0038203 TORC2 signaling(GO:0038203)
0.2 6.5 GO:0048599 oocyte development(GO:0048599)
0.2 3.7 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 1.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.2 4.5 GO:0048813 dendrite morphogenesis(GO:0048813)
0.2 0.8 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 1.7 GO:0010459 negative regulation of heart rate(GO:0010459)
0.2 0.5 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.2 3.2 GO:0030033 microvillus assembly(GO:0030033)
0.2 0.5 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.2 0.5 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.2 1.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.2 0.3 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.1 1.3 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.1 1.5 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 1.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.7 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 2.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 1.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.7 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 5.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.7 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 2.0 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 0.4 GO:0070602 regulation of chondrocyte development(GO:0061181) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 3.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 4.3 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.3 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.8 GO:0097646 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 1.9 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.9 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 1.0 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.1 2.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.5 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700) purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.8 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.1 4.2 GO:0001755 neural crest cell migration(GO:0001755)
0.1 0.9 GO:0071318 cellular response to ATP(GO:0071318)
0.1 1.3 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.8 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.7 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.4 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 2.1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.6 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.7 GO:0060982 coronary artery morphogenesis(GO:0060982)
0.1 1.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.3 GO:0097298 regulation of nucleus size(GO:0097298)
0.1 1.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 1.2 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 1.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.2 GO:1990859 cellular response to endothelin(GO:1990859)
0.1 0.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 1.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 2.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 9.6 GO:0006402 mRNA catabolic process(GO:0006402)
0.1 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.3 GO:0015671 oxygen transport(GO:0015671)
0.1 1.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 7.4 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 0.8 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.7 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.2 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
0.1 0.1 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.1 2.1 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 1.0 GO:0010574 regulation of vascular endothelial growth factor production(GO:0010574)
0.1 0.5 GO:0071578 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) zinc II ion transmembrane import(GO:0071578)
0.1 0.4 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.0 GO:0034370 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.3 GO:0061450 trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163)
0.0 2.0 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:2000016 cellular response to nitrosative stress(GO:0071500) negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.7 GO:0010225 response to UV-C(GO:0010225)
0.0 2.0 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 1.2 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.9 GO:0007143 female meiotic division(GO:0007143)
0.0 2.3 GO:0008542 visual learning(GO:0008542)
0.0 1.5 GO:0090398 cellular senescence(GO:0090398)
0.0 1.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.9 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.3 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 1.2 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.7 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 1.0 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.8 GO:0051310 metaphase plate congression(GO:0051310)
0.0 1.2 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.8 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.5 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.7 GO:0043620 regulation of DNA-templated transcription in response to stress(GO:0043620)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 1.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.8 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.6 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.4 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.0 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.9 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.7 GO:0048286 lung alveolus development(GO:0048286)
0.0 1.2 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 2.9 GO:0007051 spindle organization(GO:0007051)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.5 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.4 GO:0030832 regulation of actin polymerization or depolymerization(GO:0008064) regulation of actin filament length(GO:0030832)
0.0 0.3 GO:0060074 synapse maturation(GO:0060074)
0.0 0.3 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 0.1 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 1.9 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.8 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:0042092 type 2 immune response(GO:0042092)
0.0 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.3 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603) endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0031057 negative regulation of histone modification(GO:0031057)
0.0 0.3 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.7 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.4 GO:0071953 elastic fiber(GO:0071953)
1.6 8.1 GO:1990761 growth cone lamellipodium(GO:1990761)
1.5 4.5 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.4 5.5 GO:0043259 laminin-10 complex(GO:0043259)
0.8 3.0 GO:0043511 inhibin complex(GO:0043511)
0.7 2.2 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.7 4.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.6 2.5 GO:0090537 CERF complex(GO:0090537)
0.6 4.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.5 3.0 GO:0044305 calyx of Held(GO:0044305)
0.5 1.4 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.5 1.8 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.4 1.7 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.4 4.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.4 1.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 3.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 1.0 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.3 4.4 GO:0097542 ciliary tip(GO:0097542)
0.3 0.9 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.3 1.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.3 1.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 5.7 GO:0010369 chromocenter(GO:0010369)
0.3 2.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 3.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 2.7 GO:0032584 growth cone membrane(GO:0032584)
0.2 1.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 3.6 GO:0031011 Ino80 complex(GO:0031011)
0.2 2.1 GO:0044294 dendritic growth cone(GO:0044294)
0.2 3.6 GO:0031010 ISWI-type complex(GO:0031010)
0.2 0.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 3.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 8.0 GO:0035869 ciliary transition zone(GO:0035869)
0.2 4.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 1.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 1.8 GO:0044327 dendritic spine head(GO:0044327)
0.2 2.3 GO:0043083 synaptic cleft(GO:0043083)
0.2 8.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 3.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 1.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.2 0.8 GO:1990246 uniplex complex(GO:1990246)
0.2 0.8 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.7 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.1 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.1 1.0 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.6 GO:0061700 GATOR2 complex(GO:0061700)
0.1 13.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.6 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 10.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 4.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 9.8 GO:0055037 recycling endosome(GO:0055037)
0.1 11.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 0.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.1 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 14.5 GO:0032993 protein-DNA complex(GO:0032993)
0.1 4.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.1 2.6 GO:0016592 mediator complex(GO:0016592)
0.1 0.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 1.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.5 GO:0005916 fascia adherens(GO:0005916)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.1 2.8 GO:0016235 aggresome(GO:0016235)
0.1 4.4 GO:0005844 polysome(GO:0005844)
0.1 2.3 GO:0030673 axolemma(GO:0030673)
0.1 0.9 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 1.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 0.4 GO:0000346 transcription export complex(GO:0000346)
0.1 1.1 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.3 GO:0005827 polar microtubule(GO:0005827)
0.1 1.0 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 2.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.6 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 3.4 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 7.6 GO:0016604 nuclear body(GO:0016604)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 2.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 1.4 GO:0016528 sarcoplasm(GO:0016528)
0.0 5.5 GO:0016607 nuclear speck(GO:0016607)
0.0 1.2 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:0030118 clathrin coat(GO:0030118)
0.0 2.9 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.5 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.4 GO:0044306 neuron projection terminus(GO:0044306)
0.0 12.0 GO:0005730 nucleolus(GO:0005730)
0.0 1.4 GO:0030018 Z disc(GO:0030018)
0.0 1.9 GO:0045177 apical part of cell(GO:0045177)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 1.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
2.4 7.3 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
2.1 8.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.1 4.5 GO:0050436 microfibril binding(GO:0050436)
1.1 7.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.9 2.7 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.7 4.5 GO:0045322 unmethylated CpG binding(GO:0045322)
0.6 2.5 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.6 8.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.6 3.4 GO:0035184 histone threonine kinase activity(GO:0035184)
0.5 2.1 GO:0036033 mediator complex binding(GO:0036033)
0.5 1.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.5 4.9 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.5 1.4 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.5 2.7 GO:0005042 netrin receptor activity(GO:0005042)
0.4 1.3 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.4 2.6 GO:0001069 regulatory region RNA binding(GO:0001069)
0.4 1.6 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.4 2.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 2.8 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.4 1.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.4 2.5 GO:0032184 SUMO polymer binding(GO:0032184)
0.4 1.8 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.4 1.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 2.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.3 1.3 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.3 1.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 1.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 5.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 1.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.3 2.5 GO:0019534 toxin transporter activity(GO:0019534)
0.3 1.9 GO:0097001 ceramide binding(GO:0097001)
0.3 2.2 GO:0098821 BMP receptor activity(GO:0098821)
0.3 3.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 7.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 4.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.3 4.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.3 10.0 GO:0070412 R-SMAD binding(GO:0070412)
0.3 2.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 0.8 GO:0005118 sevenless binding(GO:0005118)
0.2 1.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 5.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 1.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.2 8.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 7.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 1.4 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 1.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 0.9 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 2.3 GO:0045499 chemorepellent activity(GO:0045499)
0.2 1.7 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529)
0.2 1.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 1.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.2 0.6 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 2.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.8 GO:0001727 lipid kinase activity(GO:0001727)
0.2 0.5 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.2 1.4 GO:0039706 co-receptor binding(GO:0039706)
0.2 0.8 GO:0097643 amylin receptor activity(GO:0097643)
0.1 9.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.1 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 1.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.4 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.1 0.9 GO:0046790 virion binding(GO:0046790)
0.1 0.3 GO:0031208 POZ domain binding(GO:0031208)
0.1 2.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 4.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 3.2 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 2.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.3 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.1 0.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 1.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.9 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 3.6 GO:0003678 DNA helicase activity(GO:0003678)
0.1 0.3 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 2.2 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.3 GO:0004096 catalase activity(GO:0004096)
0.1 2.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 2.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 7.9 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 25.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 3.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 2.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 6.6 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 2.6 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.1 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.1 GO:0005125 cytokine activity(GO:0005125)
0.1 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 6.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.6 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.9 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.7 GO:0015491 cation:cation antiporter activity(GO:0015491)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0032451 demethylase activity(GO:0032451) histone demethylase activity(GO:0032452)
0.0 0.5 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.3 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 2.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.6 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.0 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 5.8 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 3.6 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 6.9 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 15.0 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 15.7 PID_SHP2_PATHWAY SHP2 signaling
0.2 3.5 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 2.2 PID_ALK2_PATHWAY ALK2 signaling events
0.2 10.5 PID_TNF_PATHWAY TNF receptor signaling pathway
0.2 2.1 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.2 1.6 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.1 3.0 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.4 PID_EPO_PATHWAY EPO signaling pathway
0.1 10.9 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 2.2 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.1 2.6 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 1.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 2.6 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 2.7 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 1.0 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 8.4 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.7 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.1 0.6 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 1.1 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 5.0 PID_PLK1_PATHWAY PLK1 signaling events
0.1 4.9 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.1 2.3 PID_BCR_5PATHWAY BCR signaling pathway
0.1 1.5 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.1 0.7 PID_IGF1_PATHWAY IGF1 pathway
0.1 0.8 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 1.7 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 2.7 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.8 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 4.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.9 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.2 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.9 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 4.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 4.6 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.8 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.8 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.2 ST_ADRENERGIC Adrenergic Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.5 2.3 REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.4 4.8 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 2.7 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 1.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 5.2 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.2 1.8 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2 3.2 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.2 7.3 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.2 3.0 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 3.4 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 3.6 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.8 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.0 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 7.4 REACTOME_PI3K_AKT_ACTIVATION Genes involved in PI3K/AKT activation
0.1 4.1 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 1.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.6 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.0 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.7 REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.1 1.5 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.1 3.2 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.1 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 2.2 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.1 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 6.4 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.1 2.4 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 1.0 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.7 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.9 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 5.0 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.5 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 0.9 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.9 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 0.7 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.6 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.4 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.9 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.9 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.2 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 2.9 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.5 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols