Motif ID: Zfp263

Z-value: 0.779


Transcription factors associated with Zfp263:

Gene SymbolEntrez IDGene Name
Zfp263 ENSMUSG00000022529.5 Zfp263

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp263mm10_v2_chr16_+_3744089_37441450.216.7e-02Click!


Activity profile for motif Zfp263.

activity profile for motif Zfp263


Sorted Z-values histogram for motif Zfp263

Sorted Z-values for motif Zfp263



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp263

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_70111920 9.396 ENSMUST00000169074.1
ENSMUST00000021468.7
 Nin

ninein

chr4_+_104367549 7.854 ENSMUST00000106830.2
 Dab1
disabled 1
chr5_-_89883321 6.171 ENSMUST00000163159.1
ENSMUST00000061427.5
 Adamts3

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3

chr15_+_60822947 5.590 ENSMUST00000180730.1
 9930014A18Rik
RIKEN cDNA 9930014A18 gene
chr1_+_23762003 5.247 ENSMUST00000140583.1
 B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr16_-_23988852 5.080 ENSMUST00000023151.5
 Bcl6
B cell leukemia/lymphoma 6
chr1_+_23761749 4.308 ENSMUST00000144602.1
 B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr1_-_168431896 4.185 ENSMUST00000176540.1
 Pbx1
pre B cell leukemia homeobox 1
chr16_-_52452465 4.047 ENSMUST00000170035.1
ENSMUST00000164728.1
 Alcam

activated leukocyte cell adhesion molecule

chr17_-_91092715 3.990 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
 Nrxn1


neurexin I


chr10_+_13966268 3.959 ENSMUST00000015645.4
 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr7_+_36698002 3.937 ENSMUST00000021641.6
 Tshz3
teashirt zinc finger family member 3
chr1_-_21961581 3.825 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
 Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr16_-_76373014 3.758 ENSMUST00000054178.1
 Nrip1
nuclear receptor interacting protein 1
chr7_+_49246131 3.705 ENSMUST00000064395.6
 Nav2
neuron navigator 2
chr16_-_76373827 3.688 ENSMUST00000121927.1
 Nrip1
nuclear receptor interacting protein 1
chr8_-_109251698 3.671 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr2_-_113217051 3.444 ENSMUST00000080673.5
 Ryr3
ryanodine receptor 3
chr2_+_158666690 3.434 ENSMUST00000103116.3
 Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr12_-_32061221 3.415 ENSMUST00000003079.5
ENSMUST00000036497.9
 Prkar2b

protein kinase, cAMP dependent regulatory, type II beta


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 224 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 11.9 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.4 9.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.2 9.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 8.7 GO:0050885 neuromuscular process controlling balance(GO:0050885)
2.6 7.9 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.3 7.6 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
2.5 7.4 GO:0001543 ovarian follicle rupture(GO:0001543)
1.4 6.8 GO:1903587 negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.2 6.8 GO:0008045 motor neuron axon guidance(GO:0008045)
1.2 6.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
1.0 6.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
1.5 5.8 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
1.7 5.1 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
1.2 4.8 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.9 4.4 GO:0007256 activation of JNKK activity(GO:0007256)
1.1 4.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 4.2 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.7 4.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.0 4.0 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
1.3 3.9 GO:0072194 sensory perception of touch(GO:0050975) kidney smooth muscle tissue development(GO:0072194)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 111 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.1 GO:0000139 Golgi membrane(GO:0000139)
0.6 9.7 GO:0043196 varicosity(GO:0043196)
0.1 8.4 GO:0005903 brush border(GO:0005903)
1.5 7.7 GO:0036449 microtubule minus-end(GO:0036449)
0.5 7.6 GO:0042101 T cell receptor complex(GO:0042101)
1.3 6.5 GO:0030314 junctional membrane complex(GO:0030314)
0.7 6.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 6.2 GO:0030118 clathrin coat(GO:0030118)
1.0 6.0 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 5.1 GO:0005657 replication fork(GO:0005657)
0.0 4.9 GO:0016607 nuclear speck(GO:0016607)
0.0 4.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 4.4 GO:0055037 recycling endosome(GO:0055037)
0.4 4.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 4.0 GO:0034399 nuclear periphery(GO:0034399)
0.1 3.8 GO:0033268 node of Ranvier(GO:0033268)
0.2 3.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 3.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.3 3.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 3.4 GO:0010494 cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 168 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 12.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.4 10.9 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 10.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.7 9.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 8.1 GO:0042169 SH2 domain binding(GO:0042169)
1.2 7.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 6.7 GO:0004175 endopeptidase activity(GO:0004175)
0.5 6.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 6.1 GO:0005525 GTP binding(GO:0005525)
0.4 5.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.3 4.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.1 4.3 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 3.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 3.8 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.3 3.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.4 3.5 GO:0034046 poly(G) binding(GO:0034046)
0.0 3.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
1.1 3.4 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.3 3.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.8 3.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 10.4 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.2 7.9 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 6.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 4.8 PID_TNF_PATHWAY TNF receptor signaling pathway
0.1 4.7 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 4.1 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.1 3.8 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 3.4 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 3.4 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 2.8 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 2.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 2.7 PID_FGF_PATHWAY FGF signaling pathway
0.1 2.6 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.5 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 2.0 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 2.0 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.0 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.4 PID_ALK2_PATHWAY ALK2 signaling events
0.1 1.4 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 13.2 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.4 9.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 8.5 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.3 7.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 6.7 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.1 6.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 3.4 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 3.4 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 3.4 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 3.4 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 3.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 3.0 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 2.9 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.2 2.8 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.2 2.6 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.4 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 2.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.2 2.3 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 2.1 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.1 REACTOME_KINESINS Genes involved in Kinesins