Motif ID: Zfp384

Z-value: 1.091


Transcription factors associated with Zfp384:

Gene SymbolEntrez IDGene Name
Zfp384 ENSMUSG00000038346.12 Zfp384

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp384mm10_v2_chr6_+_125009113_1250091790.103.8e-01Click!


Activity profile for motif Zfp384.

activity profile for motif Zfp384


Sorted Z-values histogram for motif Zfp384

Sorted Z-values for motif Zfp384



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp384

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_94875600 15.447 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr7_-_103853199 11.597 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr6_-_23248264 9.492 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr7_-_34812677 8.032 ENSMUST00000078686.6
 Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr1_+_90203980 7.753 ENSMUST00000065587.4
ENSMUST00000159654.1
 Ackr3

atypical chemokine receptor 3

chr14_-_67715585 7.447 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
 Cdca2


cell division cycle associated 2


chr18_-_84086379 7.291 ENSMUST00000060303.8
 Tshz1
teashirt zinc finger family member 1
chr9_-_91365778 7.168 ENSMUST00000065360.3
 Zic1
zinc finger protein of the cerebellum 1
chr16_-_26989974 6.941 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr1_+_6487231 6.836 ENSMUST00000140079.1
ENSMUST00000131494.1
 St18

suppression of tumorigenicity 18

chr12_+_38780284 6.793 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
 Etv1


ets variant gene 1


chr8_-_4779513 6.736 ENSMUST00000022945.7
 Shcbp1
Shc SH2-domain binding protein 1
chr18_-_74207771 6.649 ENSMUST00000040188.8
ENSMUST00000177604.1
 Ska1

spindle and kinetochore associated complex subunit 1

chr9_-_91365756 6.516 ENSMUST00000034927.6
 Zic1
zinc finger protein of the cerebellum 1
chr19_+_37376359 6.486 ENSMUST00000012587.3
 Kif11
kinesin family member 11
chr6_+_8948608 6.377 ENSMUST00000160300.1
 Nxph1
neurexophilin 1
chr6_+_120463197 6.265 ENSMUST00000002976.3
 Il17ra
interleukin 17 receptor A
chr16_-_22161450 6.079 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr2_+_165595009 6.051 ENSMUST00000088132.6
 Eya2
eyes absent 2 homolog (Drosophila)
chr4_-_83285141 5.783 ENSMUST00000150522.1
 Ttc39b
tetratricopeptide repeat domain 39B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 462 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 16.1 GO:0007628 adult walking behavior(GO:0007628)
1.1 14.9 GO:0021979 hypothalamus cell differentiation(GO:0021979)
2.8 13.9 GO:0015671 oxygen transport(GO:0015671)
2.3 13.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.6 12.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.9 10.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
3.3 10.0 GO:0060023 soft palate development(GO:0060023)
0.2 8.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.8 8.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 8.4 GO:0006270 DNA replication initiation(GO:0006270)
0.4 7.9 GO:0016486 peptide hormone processing(GO:0016486)
0.1 7.9 GO:0051028 mRNA transport(GO:0051028)
0.1 7.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 7.5 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.1 7.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
1.8 7.3 GO:0019323 D-ribose metabolic process(GO:0006014) pentose catabolic process(GO:0019323)
0.2 7.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.9 7.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.7 7.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
2.3 6.8 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 208 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 74.2 GO:0005634 nucleus(GO:0005634)
0.3 22.1 GO:0000786 nucleosome(GO:0000786)
0.3 16.6 GO:0005876 spindle microtubule(GO:0005876)
0.1 10.4 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 8.5 GO:0032993 protein-DNA complex(GO:0032993)
1.0 7.8 GO:0005833 hemoglobin complex(GO:0005833)
0.1 7.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 7.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 7.4 GO:0005871 kinesin complex(GO:0005871)
0.3 6.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 6.6 GO:0016605 PML body(GO:0016605)
0.1 6.5 GO:0036126 sperm flagellum(GO:0036126)
0.6 6.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.7 6.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.5 6.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.3 5.6 GO:0097470 ribbon synapse(GO:0097470)
0.2 5.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
1.3 5.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.3 4.9 GO:0070938 contractile ring(GO:0070938)
0.9 4.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 312 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 24.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 23.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
2.8 13.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 11.9 GO:0003677 DNA binding(GO:0003677)
0.4 11.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 10.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 9.8 GO:0003682 chromatin binding(GO:0003682)
3.1 9.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
3.0 9.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 8.5 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.2 8.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
2.0 8.0 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.3 7.6 GO:0070410 co-SMAD binding(GO:0070410)
1.5 7.4 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
2.4 7.3 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.2 7.3 GO:0042169 SH2 domain binding(GO:0042169)
0.9 6.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 6.8 GO:0051082 unfolded protein binding(GO:0051082)
0.1 6.7 GO:0019894 kinesin binding(GO:0019894)
0.8 6.3 GO:0005095 GTPase inhibitor activity(GO:0005095)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 15.3 PID_PLK1_PATHWAY PLK1 signaling events
0.2 15.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.4 13.0 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 10.9 PID_ARF6_PATHWAY Arf6 signaling events
0.2 9.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 9.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 7.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.2 7.1 PID_AURORA_A_PATHWAY Aurora A signaling
0.2 6.3 PID_BARD1_PATHWAY BARD1 signaling events
0.1 4.3 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 4.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.4 3.9 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 3.8 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.6 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 3.5 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 3.3 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.2 3.2 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 3.2 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.1 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 2.9 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 108 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 28.0 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.6 15.7 REACTOME_KINESINS Genes involved in Kinesins
0.4 13.9 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 10.2 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
1.2 9.4 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5 8.4 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.5 8.3 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.2 7.3 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 6.1 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 5.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 5.6 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 5.5 REACTOME_G1_PHASE Genes involved in G1 Phase
0.2 5.0 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.2 4.6 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 4.4 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 4.1 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 3.9 REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.2 3.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 3.5 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)