ISMARA results: Zfp423

Motif ID: Zfp423

Z-value: 0.809

Transcription factors associated with Zfp423:

Gene Symbol	Entrez ID	Gene Name
Zfp423	ENSMUSG00000045333.9	Zfp423

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Zfp423	mm10_v2_chr8_-_87804411_87804463	-0.36	1.5e-03	Click!

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Showing 1 to 20 of 75 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_180499893	17.011	ENSMUST00000029084.2	Ntsr1	neurotensin receptor 1
chr14_+_119138415	13.427	ENSMUST00000065904.3	Hs6st3	heparan sulfate 6-O-sulfotransferase 3
chr4_+_42917234	10.491	ENSMUST00000107976.2 ENSMUST00000069184.2	N28178	expressed sequence N28178
chr6_+_110645572	7.819	ENSMUST00000071076.6 ENSMUST00000172951.1	Grm7	glutamate receptor, metabotropic 7
chr19_+_6401675	6.392	ENSMUST00000113471.1 ENSMUST00000113469.2	Rasgrp2	RAS, guanyl releasing protein 2
chr9_-_37552904	6.304	ENSMUST00000065668.5	Nrgn	neurogranin
chr14_+_70553687	6.094	ENSMUST00000161069.1	Hr	hairless
chr19_+_10041548	5.869	ENSMUST00000115995.2	Fads3	fatty acid desaturase 3
chr4_-_106464167	5.720	ENSMUST00000049507.5	Pcsk9	proprotein convertase subtilisin/kexin type 9
chr7_+_29307924	5.398	ENSMUST00000108230.1 ENSMUST00000065181.5	Dpf1	D4, zinc and double PHD fingers family 1
chr10_+_13966268	5.196	ENSMUST00000015645.4	Hivep2	human immunodeficiency virus type I enhancer binding protein 2
chr9_+_120492606	5.060	ENSMUST00000007139.4	Eif1b	eukaryotic translation initiation factor 1B
chr11_+_82101836	4.465	ENSMUST00000000194.3	Ccl12	chemokine (C-C motif) ligand 12
chrX_+_7822289	4.002	ENSMUST00000009875.4	Kcnd1	potassium voltage-gated channel, Shal-related family, member 1
chr2_+_164785823	3.641	ENSMUST00000174070.1 ENSMUST00000172577.1 ENSMUST00000056181.6	Snx21	sorting nexin family member 21
chr15_-_78718113	3.266	ENSMUST00000088592.4	Elfn2	leucine rich repeat and fibronectin type III, extracellular 2
chr10_-_62110945	3.247	ENSMUST00000142821.1 ENSMUST00000124615.1 ENSMUST00000064050.4 ENSMUST00000125704.1 ENSMUST00000142796.1	2010107G23Rik	RIKEN cDNA 2010107G23 gene
chr8_+_58912257	3.204	ENSMUST00000160055.1	BC030500	cDNA sequence BC030500
chr5_-_135934590	3.134	ENSMUST00000055808.5	Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr2_+_164785994	2.999	ENSMUST00000152471.1	Snx21	sorting nexin family member 21

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Showing 1 to 20 of 37 entries

Log-likelihood per target	Total log-likelihood	Term	Description
4.3	17.0	GO:0090238	positive regulation of arachidonic acid secretion(GO:0090238)
2.2	13.4	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.6	7.8	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	7.3	GO:0006633	fatty acid biosynthetic process(GO:0006633)
0.2	6.3	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
0.3	6.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
1.4	5.7	GO:0001920	negative regulation of receptor recycling(GO:0001920) negative regulation of low-density lipoprotein particle clearance(GO:0010989) positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805)
0.3	5.7	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.1	5.5	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	5.1	GO:0006413	translational initiation(GO:0006413)
1.5	4.5	GO:2000501	natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.0	3.5	GO:0032526	response to retinoic acid(GO:0032526)
0.0	3.3	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	3.2	GO:0071805	potassium ion transmembrane transport(GO:0071805)
0.0	3.1	GO:0048167	regulation of synaptic plasticity(GO:0048167)
0.0	2.7	GO:0031641	regulation of myelination(GO:0031641)
0.4	2.3	GO:1990928	response to amino acid starvation(GO:1990928)
0.2	2.3	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	2.3	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.5	2.0	GO:0097477	lateral motor column neuron migration(GO:0097477)

Gene overrepresentation in cellular_component category:

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Showing 1 to 20 of 21 entries

Log-likelihood per target	Total log-likelihood	Term	Description
4.3	17.0	GO:0032280	symmetric synapse(GO:0032280)
0.7	7.8	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.1	6.6	GO:0031901	early endosome membrane(GO:0031901)
0.5	6.3	GO:0044327	dendritic spine head(GO:0044327)
0.1	6.1	GO:0000118	histone deacetylase complex(GO:0000118)
1.9	5.7	GO:1990667	PCSK9-AnxA2 complex(GO:1990667)
0.2	5.4	GO:0071565	nBAF complex(GO:0071565)
0.0	4.0	GO:0043209	myelin sheath(GO:0043209)
0.0	3.2	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	2.5	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	2.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	2.0	GO:0043204	perikaryon(GO:0043204)
0.1	1.5	GO:0097225	sperm midpiece(GO:0097225)
0.0	1.4	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	1.0	GO:0005795	Golgi stack(GO:0005795)
0.0	0.9	GO:0000930	gamma-tubulin complex(GO:0000930)
0.3	0.8	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.8	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.8	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.7	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)

Gene overrepresentation in molecular_function category:

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Showing 1 to 20 of 36 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	17.0	GO:0008188	neuropeptide receptor activity(GO:0008188)
3.4	13.4	GO:0017095	heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
2.6	7.8	GO:0070905	serine binding(GO:0070905)
0.1	6.6	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	6.4	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.3	6.3	GO:0070300	phosphatidic acid binding(GO:0070300)
0.4	6.1	GO:0042809	vitamin D receptor binding(GO:0042809)
1.9	5.7	GO:0034190	very-low-density lipoprotein particle binding(GO:0034189) apolipoprotein receptor binding(GO:0034190)
0.5	5.7	GO:0008430	selenium binding(GO:0008430)
0.1	5.1	GO:0003743	translation initiation factor activity(GO:0003743)
1.1	4.5	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.8	4.0	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	3.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	3.3	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.1	3.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.9	2.7	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.2	2.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.4	2.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1	1.7	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	1.5	GO:0043014	alpha-tubulin binding(GO:0043014)

Gene overrepresentation in C2:CP category:

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Showing 1 to 11 of 11 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.4	PID_RAS_PATHWAY	Regulation of Ras family activation
0.1	5.8	PID_A6B1_A6B4_INTEGRIN_PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	3.3	NABA_ECM_AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	2.3	PID_MTOR_4PATHWAY	mTOR signaling pathway
0.1	2.0	PID_LIS1_PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.9	PID_DELTA_NP63_PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.9	SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.9	PID_LKB1_PATHWAY	LKB1 signaling events
0.0	0.8	PID_UPA_UPAR_PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.2	PID_TCR_JNK_PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.1	PID_P38_GAMMA_DELTA_PATHWAY	Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

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Showing 1 to 17 of 17 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	17.0	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.3	13.4	REACTOME_HS_GAG_BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.6	7.8	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2	6.4	REACTOME_RAP1_SIGNALLING	Genes involved in Rap1 signalling
0.1	3.2	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	3.1	REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	2.7	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	2.3	REACTOME_MTORC1_MEDIATED_SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	2.0	REACTOME_MRNA_SPLICING	Genes involved in mRNA Splicing
0.0	1.7	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1	1.4	REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	1.2	REACTOME_HDL_MEDIATED_LIPID_TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	1.0	REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1	0.8	REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	0.8	REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.5	REACTOME_NCAM1_INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.2	REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation