Motif ID: Zfp652

Z-value: 0.927


Transcription factors associated with Zfp652:

Gene SymbolEntrez IDGene Name
Zfp652 ENSMUSG00000075595.3 Zfp652

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp652mm10_v2_chr11_+_95749067_957490670.065.8e-01Click!


Activity profile for motif Zfp652.

activity profile for motif Zfp652


Sorted Z-values histogram for motif Zfp652

Sorted Z-values for motif Zfp652



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp652

PNG image of the network

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Top targets:


Showing 1 to 20 of 102 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_53707532 22.954 ENSMUST00000031093.3
 Cckar
cholecystokinin A receptor
chr10_+_26229707 22.029 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr4_-_63403330 18.635 ENSMUST00000035724.4
 Akna
AT-hook transcription factor
chr10_-_92165159 16.557 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
 Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr1_-_138847579 16.030 ENSMUST00000093486.3
ENSMUST00000046870.6
 Lhx9

LIM homeobox protein 9

chr6_+_83137089 11.431 ENSMUST00000121093.1
ENSMUST00000087938.4
 Rtkn

rhotekin

chr14_+_73237891 10.184 ENSMUST00000044405.6
 Lpar6
lysophosphatidic acid receptor 6
chr5_+_115908644 9.847 ENSMUST00000141101.1
 Cit
citron
chr11_-_94242701 9.050 ENSMUST00000061469.3
 Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr1_+_153665274 8.782 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr14_+_55853997 8.436 ENSMUST00000100529.3
 Nynrin
NYN domain and retroviral integrase containing
chr1_+_153665666 8.303 ENSMUST00000111814.1
ENSMUST00000111810.1
 Rgs8

regulator of G-protein signaling 8

chr1_-_118982551 8.113 ENSMUST00000159678.1
 Gli2
GLI-Kruppel family member GLI2
chr6_+_124808885 7.945 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
 Spsb2


splA/ryanodine receptor domain and SOCS box containing 2


chr6_+_137754529 7.513 ENSMUST00000087675.6
 Dera
2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chr10_-_6980376 7.311 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr2_-_79456750 7.296 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr2_-_180225812 7.281 ENSMUST00000015791.5
 Lama5
laminin, alpha 5
chr1_+_153665587 7.077 ENSMUST00000147700.1
 Rgs8
regulator of G-protein signaling 8
chr1_+_184034381 7.031 ENSMUST00000048655.7
 Dusp10
dual specificity phosphatase 10

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 30.9 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
7.7 23.0 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.0 17.7 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
3.2 16.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 11.4 GO:0007266 Rho protein signal transduction(GO:0007266)
0.5 10.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.5 9.8 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 9.1 GO:0048747 muscle fiber development(GO:0048747)
1.1 8.4 GO:0015074 DNA integration(GO:0015074)
2.0 8.1 GO:0060032 notochord regression(GO:0060032)
1.9 7.5 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
1.8 7.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.2 7.3 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
1.4 7.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.7 6.8 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.6 6.5 GO:0034983 peptidyl-lysine deacetylation(GO:0034983) regulation of skeletal muscle fiber development(GO:0048742)
0.0 5.7 GO:0007283 spermatogenesis(GO:0007283)
0.1 5.6 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 5.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 5.2 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 25.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 23.0 GO:0043195 terminal bouton(GO:0043195)
0.5 19.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 18.6 GO:0001650 fibrillar center(GO:0001650)
0.2 10.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.6 8.1 GO:0097542 ciliary tip(GO:0097542)
1.8 7.3 GO:0043259 laminin-10 complex(GO:0043259)
0.1 6.5 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 5.2 GO:0005882 intermediate filament(GO:0005882)
0.3 5.0 GO:0035102 PRC1 complex(GO:0035102)
0.3 4.1 GO:0031105 septin complex(GO:0031105)
0.1 3.0 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
1.0 2.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.3 2.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.3 2.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.6 2.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 2.2 GO:0005922 connexon complex(GO:0005922)
0.2 2.1 GO:0061574 ASAP complex(GO:0061574)
0.6 1.9 GO:0005588 collagen type V trimer(GO:0005588)
0.0 1.9 GO:0016235 aggresome(GO:0016235)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 30.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 23.0 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 18.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.8 15.6 GO:0035497 cAMP response element binding(GO:0035497)
1.4 11.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
1.5 10.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.8 9.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 8.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.6 7.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.5 7.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) mitogen-activated protein kinase p38 binding(GO:0048273)
0.4 6.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.3 6.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 6.4 GO:0097110 scaffold protein binding(GO:0097110)
0.1 6.2 GO:0070888 E-box binding(GO:0070888)
0.1 5.8 GO:0008013 beta-catenin binding(GO:0008013)
0.3 5.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 5.4 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.6 5.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.8 4.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 4.5 GO:0070182 DNA polymerase binding(GO:0070182)

Gene overrepresentation in C2:CP category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 9.8 PID_RHOA_PATHWAY RhoA signaling pathway
0.3 8.1 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.9 7.3 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 7.3 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 7.0 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.1 6.5 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 4.9 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 4.5 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.1 3.6 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 3.3 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 2.8 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 1.9 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 1.9 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.7 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID_ATM_PATHWAY ATM pathway
0.0 0.2 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 30.9 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.3 23.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.5 17.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
1.1 10.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 7.9 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.3 7.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 5.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 5.1 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 3.8 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 3.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 3.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 2.9 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.2 2.2 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 2.2 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.2 1.9 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.4 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.0 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks