Motif ID: Zfp691

Z-value: 0.489


Transcription factors associated with Zfp691:

Gene SymbolEntrez IDGene Name
Zfp691 ENSMUSG00000045268.7 Zfp691

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp691mm10_v2_chr4_-_119174178_119174221-0.324.4e-03Click!


Activity profile for motif Zfp691.

activity profile for motif Zfp691


Sorted Z-values histogram for motif Zfp691

Sorted Z-values for motif Zfp691



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp691

PNG image of the network

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Top targets:


Showing 1 to 20 of 99 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_119138415 4.877 ENSMUST00000065904.3
 Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr8_+_72319033 3.237 ENSMUST00000067912.7
 Klf2
Kruppel-like factor 2 (lung)
chr10_-_86732409 2.691 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr2_+_26591423 2.446 ENSMUST00000152988.2
ENSMUST00000149789.1
 Egfl7

EGF-like domain 7

chr9_+_32696005 2.429 ENSMUST00000034534.6
ENSMUST00000050797.7
ENSMUST00000184887.1
 Ets1


E26 avian leukemia oncogene 1, 5' domain


chr5_+_37050854 2.334 ENSMUST00000043794.4
 Jakmip1
janus kinase and microtubule interacting protein 1
chr3_-_82074639 2.278 ENSMUST00000029635.8
 Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr10_+_81183263 2.253 ENSMUST00000047665.6
 Dapk3
death-associated protein kinase 3
chr14_+_27238018 1.932 ENSMUST00000049206.5
 Arhgef3
Rho guanine nucleotide exchange factor (GEF) 3
chr2_-_10130638 1.772 ENSMUST00000042290.7
 Itih2
inter-alpha trypsin inhibitor, heavy chain 2
chr13_-_60897439 1.765 ENSMUST00000171347.1
ENSMUST00000021884.8
 Ctla2b

cytotoxic T lymphocyte-associated protein 2 beta

chr1_+_51289106 1.737 ENSMUST00000051572.6
 Sdpr
serum deprivation response
chr17_+_34203527 1.570 ENSMUST00000025197.5
 Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chrX_-_101268218 1.497 ENSMUST00000033664.7
 Il2rg
interleukin 2 receptor, gamma chain
chr10_+_81183000 1.483 ENSMUST00000178422.1
 Dapk3
death-associated protein kinase 3
chr15_+_82252397 1.425 ENSMUST00000136948.1
 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr4_-_129623870 1.367 ENSMUST00000106035.1
ENSMUST00000150357.1
ENSMUST00000030586.8
 Ccdc28b


coiled coil domain containing 28B


chr3_+_98280427 1.333 ENSMUST00000090746.2
ENSMUST00000120541.1
 Hmgcs2

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2

chr10_-_81183849 1.330 ENSMUST00000056086.4
 4930442H23Rik
RIKEN cDNA 4930442H23 gene
chr13_-_34130345 1.329 ENSMUST00000075774.3
 Tubb2b
tubulin, beta 2B class IIB

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 4.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.2 3.7 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.5 3.2 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.5 2.4 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 2.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.8 2.3 GO:0099548 trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 1.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.5 1.6 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.5 1.5 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.1 1.3 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 1.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.1 1.2 GO:0034312 diol biosynthetic process(GO:0034312)
0.2 1.1 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2 1.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 1.0 GO:0021527 spinal cord association neuron differentiation(GO:0021527) forebrain dorsal/ventral pattern formation(GO:0021798)
0.2 0.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.9 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.3 0.8 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 0.8 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.8 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0005884 actin filament(GO:0005884)
0.1 2.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.8 GO:0072562 blood microparticle(GO:0072562)
0.2 1.6 GO:0042825 TAP complex(GO:0042825)
0.2 1.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 0.9 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.9 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)
0.1 0.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.7 GO:0043203 axon hillock(GO:0043203)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.5 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.5 GO:0097433 dense body(GO:0097433)
0.0 0.5 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 4.9 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 2.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 2.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.4 GO:0005112 Notch binding(GO:0005112)
0.2 2.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 2.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 2.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.4 1.6 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.0 1.5 GO:0019955 cytokine binding(GO:0019955)
0.0 1.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 1.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 1.3 GO:0050699 WW domain binding(GO:0050699)
0.0 1.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 1.1 GO:0042923 neuropeptide binding(GO:0042923)
0.2 1.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.2 0.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)

Gene overrepresentation in C2:CP category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.9 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 2.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.9 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 1.3 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID_MYC_PATHWAY C-MYC pathway
0.0 0.5 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.9 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 3.7 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.3 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 1.6 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.5 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.3 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.3 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.2 REACTOME_TRNA_AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 1.1 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.8 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.6 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines