Motif ID: Zfx_Zfp711

Z-value: 3.150

Transcription factors associated with Zfx_Zfp711:

Gene SymbolEntrez IDGene Name
Zfp711 ENSMUSG00000025529.8 Zfp711
Zfx ENSMUSG00000079509.4 Zfx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfxmm10_v2_chrX_-_94123359_941234120.462.4e-05Click!
Zfp711mm10_v2_chrX_+_112600526_1126005260.207.5e-02Click!


Activity profile for motif Zfx_Zfp711.

activity profile for motif Zfx_Zfp711


Sorted Z-values histogram for motif Zfx_Zfp711

Sorted Z-values for motif Zfx_Zfp711



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfx_Zfp711

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_34372004 28.241 ENSMUST00000113132.2
ENSMUST00000040638.8
 Pbx3

pre B cell leukemia homeobox 3

chr2_-_180225812 27.762 ENSMUST00000015791.5
 Lama5
laminin, alpha 5
chr4_+_109978004 23.171 ENSMUST00000061187.3
 Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr15_-_75747922 20.746 ENSMUST00000062002.4
 Mafa
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr5_-_115119277 20.709 ENSMUST00000031524.7
 Acads
acyl-Coenzyme A dehydrogenase, short chain
chr9_-_72111827 19.423 ENSMUST00000183404.1
ENSMUST00000184783.1
 Tcf12

transcription factor 12

chr6_+_47454320 18.569 ENSMUST00000031697.8
 Cul1
cullin 1
chr17_-_28350747 18.534 ENSMUST00000080572.7
ENSMUST00000156862.1
 Tead3

TEA domain family member 3

chr8_+_127064107 18.263 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
 Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr19_-_30175414 18.069 ENSMUST00000025778.7
 Gldc
glycine decarboxylase
chr2_+_172549581 17.278 ENSMUST00000030391.2
 Tfap2c
transcription factor AP-2, gamma
chr2_+_105675478 17.018 ENSMUST00000167211.2
ENSMUST00000111083.3
 Pax6

paired box gene 6

chr17_-_28350600 16.503 ENSMUST00000114799.1
 Tead3
TEA domain family member 3
chr2_+_130295148 16.250 ENSMUST00000110288.2
 Ebf4
early B cell factor 4
chr1_+_172312367 15.434 ENSMUST00000039506.9
 Igsf8
immunoglobulin superfamily, member 8
chr11_-_12037391 15.033 ENSMUST00000093321.5
 Grb10
growth factor receptor bound protein 10
chr11_+_60104971 14.976 ENSMUST00000064190.6
 Rai1
retinoic acid induced 1
chr2_-_104816696 14.841 ENSMUST00000117237.1
 Qser1
glutamine and serine rich 1
chr5_-_124095749 14.816 ENSMUST00000031354.4
 Abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chrX_-_94123359 14.522 ENSMUST00000137853.1
ENSMUST00000088102.5
ENSMUST00000113927.1
 Zfx


zinc finger protein X-linked



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,127 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.3 39.1 GO:0003190 atrioventricular valve formation(GO:0003190)
3.5 38.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
7.5 37.7 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
6.1 36.7 GO:0003383 apical constriction(GO:0003383)
0.5 34.9 GO:0036503 ERAD pathway(GO:0036503)
2.4 32.9 GO:0055059 asymmetric neuroblast division(GO:0055059)
2.2 31.2 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
7.8 31.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
1.4 30.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.8 29.6 GO:0001738 morphogenesis of a polarized epithelium(GO:0001738)
1.8 29.2 GO:0048368 lateral mesoderm development(GO:0048368)
4.0 28.1 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
8.7 26.2 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
2.6 26.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
1.0 24.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
2.7 24.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.7 23.8 GO:0035411 catenin import into nucleus(GO:0035411)
1.7 23.7 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
7.7 23.1 GO:0030421 defecation(GO:0030421)
1.5 22.9 GO:0033234 negative regulation of protein sumoylation(GO:0033234)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 340 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 420.4 GO:0005634 nucleus(GO:0005634)
0.2 295.5 GO:0005654 nucleoplasm(GO:0005654)
0.5 123.2 GO:0005667 transcription factor complex(GO:0005667)
0.8 118.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.9 80.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 51.2 GO:0005694 chromosome(GO:0005694)
0.5 45.6 GO:0000776 kinetochore(GO:0000776)
0.2 43.5 GO:0000790 nuclear chromatin(GO:0000790)
0.9 35.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.6 34.9 GO:0005657 replication fork(GO:0005657)
0.4 32.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
8.2 32.7 GO:0043259 laminin-10 complex(GO:0043259)
0.4 27.5 GO:0005814 centriole(GO:0005814)
3.3 26.6 GO:0033269 internode region of axon(GO:0033269)
1.7 26.2 GO:0070938 contractile ring(GO:0070938)
1.1 25.9 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.5 25.9 GO:0005925 focal adhesion(GO:0005925)
0.4 25.9 GO:0005844 polysome(GO:0005844)
6.3 25.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
2.7 24.5 GO:1990909 Wnt signalosome(GO:1990909)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 573 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 261.3 GO:0003677 DNA binding(GO:0003677)
0.5 122.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.5 79.9 GO:0042393 histone binding(GO:0042393)
0.6 72.6 GO:0003714 transcription corepressor activity(GO:0003714)
1.5 60.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.9 56.0 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
2.8 52.8 GO:0035497 cAMP response element binding(GO:0035497)
3.2 50.6 GO:0003680 AT DNA binding(GO:0003680)
0.9 43.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.1 41.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
1.0 37.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.5 37.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.6 35.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 33.7 GO:0004386 helicase activity(GO:0004386)
0.2 31.9 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
1.2 31.2 GO:0000217 DNA secondary structure binding(GO:0000217)
0.8 30.9 GO:0030332 cyclin binding(GO:0030332)
1.7 30.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.3 30.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
3.9 27.4 GO:0098821 BMP receptor activity(GO:0098821)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 106.3 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.9 62.7 PID_E2F_PATHWAY E2F transcription factor network
1.6 48.2 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.8 48.1 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.9 44.6 PID_PLK1_PATHWAY PLK1 signaling events
0.9 44.4 PID_AURORA_B_PATHWAY Aurora B signaling
1.0 43.4 PID_BMP_PATHWAY BMP receptor signaling
1.5 39.8 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
4.6 36.9 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.6 36.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity
1.0 33.4 PID_BARD1_PATHWAY BARD1 signaling events
0.7 31.2 PID_ILK_PATHWAY Integrin-linked kinase signaling
2.2 30.6 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.6 30.0 PID_CDC42_PATHWAY CDC42 signaling events
0.8 29.6 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.6 28.2 PID_TELOMERASE_PATHWAY Regulation of Telomerase
1.0 27.0 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
1.6 26.7 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.8 24.5 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.7 22.9 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 144 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 107.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
2.6 87.1 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
2.4 74.6 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.8 64.2 REACTOME_MYOGENESIS Genes involved in Myogenesis
2.7 54.6 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
1.8 53.5 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
1.7 52.8 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.7 43.1 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 42.7 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
1.5 41.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
1.3 39.1 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
3.0 33.5 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
1.3 31.3 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
1.6 27.0 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.5 26.3 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.4 24.1 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
1.1 22.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.7 21.6 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.8 20.6 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
1.0 19.2 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis