Motif ID: Zkscan3

Z-value: 0.296


Transcription factors associated with Zkscan3:

Gene SymbolEntrez IDGene Name
Zkscan3 ENSMUSG00000021327.12 Zkscan3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan3mm10_v2_chr13_-_21402688_21402755-0.103.8e-01Click!


Activity profile for motif Zkscan3.

activity profile for motif Zkscan3


Sorted Z-values histogram for motif Zkscan3

Sorted Z-values for motif Zkscan3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan3

PNG image of the network

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Top targets:


Showing 1 to 20 of 70 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_24985840 0.994 ENSMUST00000075081.6
1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr11_-_75422586 0.732 ENSMUST00000138661.1
ENSMUST00000000769.7
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr13_-_100786402 0.685 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
Ccnb1


cyclin B1


chr18_+_61105844 0.624 ENSMUST00000115268.3
Csf1r
colony stimulating factor 1 receptor
chr11_-_75422524 0.578 ENSMUST00000125982.1
ENSMUST00000137103.1
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr2_+_104095796 0.570 ENSMUST00000040423.5
ENSMUST00000168176.1
Cd59a

CD59a antigen

chr3_+_146500071 0.511 ENSMUST00000119130.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr6_-_122856151 0.490 ENSMUST00000042081.8
C3ar1
complement component 3a receptor 1
chr8_+_31091593 0.396 ENSMUST00000161713.1
Dusp26
dual specificity phosphatase 26 (putative)
chr13_-_19395728 0.393 ENSMUST00000039694.7
Stard3nl
STARD3 N-terminal like
chr3_+_146499850 0.373 ENSMUST00000118280.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr1_+_180942452 0.355 ENSMUST00000027800.8
Tmem63a
transmembrane protein 63a
chr2_-_66634952 0.350 ENSMUST00000100064.2
ENSMUST00000100063.2
Scn9a

sodium channel, voltage-gated, type IX, alpha

chr3_+_79629074 0.340 ENSMUST00000029388.8
4930579G24Rik
RIKEN cDNA 4930579G24 gene
chr11_-_102365111 0.325 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr7_+_101896340 0.319 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr5_-_88675613 0.317 ENSMUST00000113234.1
ENSMUST00000153565.1
Grsf1

G-rich RNA sequence binding factor 1

chr13_-_32851176 0.314 ENSMUST00000091668.5
ENSMUST00000076352.6
Serpinb1a

serine (or cysteine) peptidase inhibitor, clade B, member 1a

chr8_+_70616816 0.314 ENSMUST00000052437.3
Lrrc25
leucine rich repeat containing 25
chr8_+_94810446 0.301 ENSMUST00000034232.1
Ccl17
chemokine (C-C motif) ligand 17

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 0.7 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.2 0.6 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 0.6 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.2 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.5 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.4 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.4 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.3 GO:1904207 chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.3 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0043203 axon hillock(GO:0043203)
0.3 0.9 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 0.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2 0.6 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0030690 Noc1p-Noc2p complex(GO:0030690)

Gene overrepresentation in molecular_function category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 0.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.7 GO:0001848 complement binding(GO:0001848)
0.2 0.5 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.4 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.1 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.6 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 0.7 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.1 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease