Motif ID: AACACUG

Z-value: 1.107

Mature miRNA associated with seed AACACUG:

NamemiRBase Accession
mmu-miR-141 MIMAT0000153
mmu-miR-200a MIMAT0000519



Activity profile for motif AACACUG.

activity profile for motif AACACUG


Sorted Z-values histogram for motif AACACUG

Sorted Z-values for motif AACACUG



Network of associatons between targets according to the STRING database.



First level regulatory network of AACACUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr8_+_46593141 6.662 NM_172752
Sorbs2
sorbin and SH3 domain containing 2
chr9_+_113721698 4.937 NM_001081960
NM_029633
Clasp2

CLIP associating protein 2

chr8_+_130882920 4.648 NM_008737
Nrp1
neuropilin 1
chr12_+_30213224 4.545 NM_001093775
NM_001093778
NM_008666
Myt1l


myelin transcription factor 1-like


chr13_-_14615371 4.108 NM_001081348
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr6_-_32538191 4.004 NM_175750
Plxna4
plexin A4
chr1_+_19198994 3.625 NM_009334
Tcfap2b
transcription factor AP-2 beta
chr19_-_19185685 3.091 NM_001043354
Rorb
RAR-related orphan receptor beta
chr11_+_53380870 3.069 NM_008443
Kif3a
kinesin family member 3A
chr1_+_189821727 3.050 NM_011935
Esrrg
estrogen-related receptor gamma
chr12_+_30219769 2.889 NM_001093776
Myt1l
myelin transcription factor 1-like
chr18_+_10325174 2.876 NM_001083628
Greb1l
growth regulation by estrogen in breast cancer-like
chr14_+_12386043 2.797 NM_008981
Ptprg
protein tyrosine phosphatase, receptor type, G
chr6_-_98978185 2.672 NM_001197322
Foxp1
forkhead box P1
chr13_+_40982534 2.549 NM_008105
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr2_-_44968728 2.466 NM_015753
Zeb2
zinc finger E-box binding homeobox 2
chr15_+_30102306 2.415 NM_008729
Ctnnd2
catenin (cadherin associated protein), delta 2
chr5_-_84846348 2.340 NM_007937
Epha5
Eph receptor A5
chr11_+_97311458 2.323 NM_021493
Arhgap23
Rho GTPase activating protein 23
chr5_-_138721164 2.311 NM_172412
Gpc2
glypican 2 (cerebroglycan)
chr7_-_72301384 2.119 NM_183087
Fam189a1
family with sequence similarity 189, member A1
chr18_-_31606908 2.087 NM_009308
Syt4
synaptotagmin IV
chr4_+_21858472 2.081 NM_175234
6230409E13Rik
RIKEN cDNA 6230409E13 gene
chr6_+_15135505 2.064 NM_212435
Foxp2
forkhead box P2
chr1_+_160292470 2.064 NM_007495
Astn1
astrotactin 1
chr9_+_47338431 2.055 NM_001025600
NM_018770
NM_207675
NM_207676
Cadm1



cell adhesion molecule 1



chrX_-_140367467 2.044 NM_001110222
NM_001110223
NM_001110224
NM_010025
Dcx



doublecortin



chr1_-_134638361 2.026 NM_001160317
NM_182716
Nfasc

neurofascin

chr9_-_113935832 1.883 NM_178624
Fbxl2
F-box and leucine-rich repeat protein 2
chr4_+_28740280 1.797 NM_001122889
NM_010141
Epha7

Eph receptor A7

chr4_-_91042997 1.757 NM_001177883
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr12_-_28027541 1.616 NM_009234
Sox11
SRY-box containing gene 11
chr1_-_128389495 1.611 NM_172484
Nckap5
NCK-associated protein 5
chr15_-_56526052 1.594 NM_008216
Has2
hyaluronan synthase 2
chr2_+_28496752 1.532 NM_022887
Tsc1
tuberous sclerosis 1
chr4_+_40090297 1.527 NM_007386
Aco1
aconitase 1
chr4_-_107973683 1.510 NM_001033634
Zyg11b
zyg-ll homolog B (C. elegans)
chr6_+_71657791 1.491 NM_178608
Reep1
receptor accessory protein 1
chr11_+_93905501 1.485 NM_001025428
NM_001025429
NM_001025430
Spag9


sperm associated antigen 9


chr2_+_68699498 1.473 NM_172856
Lass6
LAG1 homolog, ceramide synthase 6
chr13_-_40829082 1.471 NM_011547
Tcfap2a
transcription factor AP-2, alpha
chr3_-_84024766 1.427 NM_030706
Trim2
tripartite motif-containing 2
chr4_+_13670425 1.418 NM_001111026
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_-_91492065 1.370 NM_020252
NM_177284
Nrxn1

neurexin I

chr10_-_42894259 1.364 NM_175407
Sobp
sine oculis-binding protein homolog (Drosophila)
chr5_-_29704889 1.286 NM_020295
Lmbr1
limb region 1
chr1_-_158869650 1.275 NM_001159965
NM_001159967
NM_001159968
NM_023884
Ralgps2



Ral GEF with PH domain and SH3 binding motif 2



chr5_+_19413335 1.263 NM_001170745
NM_015823
Magi2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chr4_-_135050358 1.263 NM_028995
Nipal3
NIPA-like domain containing 3
chr16_-_44139087 1.252 NM_007508
Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
chr6_-_84543739 1.251 NM_175475
NM_001177713
Cyp26b1

cytochrome P450, family 26, subfamily b, polypeptide 1

chrX_-_130223380 1.218 NM_001105245
NM_001105246
Pcdh19

protocadherin 19

chr2_-_60801248 1.184 NM_020296
Rbms1
RNA binding motif, single stranded interacting protein 1
chr1_-_52290058 1.163 NM_001081081
NM_001113383
Gls

glutaminase

chr19_-_24936327 1.162 NM_175013
Pgm5
phosphoglucomutase 5
chr1_-_171677653 1.136 NM_009062
Rgs4
regulator of G-protein signaling 4
chr6_+_14851348 1.123 NM_053242
Foxp2
forkhead box P2
chr17_-_36046961 1.104 NM_001142744
NM_001142745
NM_028476
Atat1


alpha tubulin acetyltransferase 1


chr1_-_97564139 1.104 NM_001159745
NM_009183
St8sia4

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

chr9_+_37296867 1.090 NM_146222
BC024479
cDNA sequence BC024479
chr4_+_13678443 1.090 NM_001111027
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_157250020 1.086 NM_001025395
NM_009271
Src

Rous sarcoma oncogene

chr9_-_45792865 1.078 NM_008775
Pafah1b2
2610005M20Rik
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
RIKEN cDNA 2610005M20 gene
chr16_+_32608981 1.071 NM_011638
Tfrc
transferrin receptor
chr4_-_115612507 1.066 NM_001025567
NM_130865
Dmbx1

diencephalon/mesencephalon homeobox 1

chr3_+_109143558 1.061 NM_020505
Vav3
vav 3 oncogene
chr1_+_168309297 1.051 NM_030245
Tada1
transcriptional adaptor 1
chr17_+_73185961 1.033 NM_027166
Ypel5
yippee-like 5 (Drosophila)
chr1_-_12980994 1.026 NM_172841
Slco5a1
solute carrier organic anion transporter family, member 5A1
chr4_+_42930076 1.002 NM_172690
N28178
expressed sequence N28178
chr13_+_91600662 0.982 NM_024186
NM_024272
Ssbp2

single-stranded DNA binding protein 2

chr12_+_75098739 0.981 NM_172804
Syt16
synaptotagmin XVI
chr8_+_13869640 0.908 NM_181854
Zfp828
zinc finger protein 828
chr2_+_48669628 0.907 NM_007396
Acvr2a
activin receptor IIA
chr2_+_106535757 0.904 NM_029837
Mpped2
metallophosphoesterase domain containing 2
chr2_+_107130745 0.903 NM_021275
Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr9_-_53823107 0.893 NM_177769
Elmod1
ELMO domain containing 1
chr12_+_53800369 0.888 NM_198111
Akap6
A kinase (PRKA) anchor protein 6
chr7_-_80686630 0.886 NM_001081345
Chd2
chromodomain helicase DNA binding protein 2
chr8_+_124474432 0.885 NM_001110100
NM_016812
Banp

BTG3 associated nuclear protein

chr2_-_25838722 0.882 NM_001115076
Camsap1
calmodulin regulated spectrin-associated protein 1
chr1_-_153937364 0.876 NM_197990
LOC545371
1700025G04Rik
hypothetical protein LOC545371
RIKEN cDNA 1700025G04 gene
chrX_-_35605626 0.874 NM_172930
Fam70a
family with sequence similarity 70, member A
chr2_+_29821079 0.870 NM_001076554
NM_001177667
NM_001177668
Spna2


spectrin alpha 2


chr19_-_47036782 0.867 NM_029810
Nt5c2
5'-nucleotidase, cytosolic II
chr2_+_121692687 0.867 NM_177054
NM_199038
Casc4

cancer susceptibility candidate 4

chr11_+_44332426 0.865 NM_028862
Rnf145
ring finger protein 145
chr19_-_29887442 0.863 NM_177721
Ranbp6
RAN binding protein 6
chr1_-_91827726 0.855 NM_010262
Gbx2
gastrulation brain homeobox 2
chr11_-_106649652 0.852 NM_007840
Ddx5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr5_-_110815980 0.852 NM_028596
Fbrsl1
fibrosin-like 1
chr6_+_30351902 0.852 NM_029742
Klhdc10
kelch domain containing 10
chr8_+_3393005 0.833 NM_133962
Arhgef18
rho/rac guanine nucleotide exchange factor (GEF) 18
chr2_-_134469806 0.821 NM_029148
Tmx4
thioredoxin-related transmembrane protein 4
chrX_+_71574403 0.820 NM_008883
Plxna3
plexin A3
chr12_+_96930429 0.818 NM_201518
Flrt2
fibronectin leucine rich transmembrane protein 2
chr5_-_102498929 0.813 NM_172882
Wdfy3
WD repeat and FYVE domain containing 3
chr2_+_65683823 0.804 NM_153409
NM_178634
Csrnp3

cysteine-serine-rich nuclear protein 3

chrX_+_97963061 0.796 NM_001177778
NM_016747
Dlg3

discs, large homolog 3 (Drosophila)

chr9_+_59139356 0.794 NM_028121
Adpgk
ADP-dependent glucokinase
chr4_+_11083585 0.789 NM_021897
Trp53inp1
transformation related protein 53 inducible nuclear protein 1
chr15_-_48623520 0.779 NM_001081391
Csmd3
CUB and Sushi multiple domains 3
chr12_+_25659777 0.774 NM_001081378
Kidins220
kinase D-interacting substrate 220
chr1_+_169619688 0.773 NM_033652
Lmx1a
LIM homeobox transcription factor 1 alpha
chr9_+_40076800 0.769 NM_001083917
NM_153522
NM_178227
Scn3b


sodium channel, voltage-gated, type III, beta


chr14_-_80171003 0.769 NM_001042726
NM_021543
Pcdh8

protocadherin 8

chr19_-_28085534 0.755 NM_011265
Rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr19_+_36908682 0.750 NM_001163635
Tnks2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr7_-_11080687 0.739 NM_009577
Zik1
zinc finger protein interacting with K protein 1
chr4_+_111087610 0.739 NM_026279
Bend5
BEN domain containing 5
chr15_-_103045710 0.735 NM_001110216
NM_007626
Cbx5

chromobox homolog 5 (Drosophila HP1a)

chr2_-_60719361 0.733 NM_001141931
NM_001141932
Rbms1

RNA binding motif, single stranded interacting protein 1

chr11_-_87172419 0.730 NM_177167
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr1_-_138242666 0.729 NM_001081360
Camsap1l1
calmodulin regulated spectrin-associated protein 1-like 1
chr18_+_23962468 0.725 NM_153058
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr10_-_25798768 0.725 NM_029881
Tmem200a
transmembrane protein 200A
chr1_+_6204729 0.724 NM_009826
Rb1cc1
RB1-inducible coiled-coil 1
chr9_-_55785907 0.724 NM_001081341
Scaper
S phase cyclin A-associated protein in the ER
chr2_-_27331122 0.722 NM_001113573
NM_001113574
Brd3

bromodomain containing 3

chr15_-_60656465 0.708 NM_001162926
Fam84b
family with sequence similarity 84, member B
chr2_-_51004604 0.701 NM_028810
Rnd3
Rho family GTPase 3
chr18_+_59334993 0.699 NM_001081328
Chsy3
chondroitin sulfate synthase 3
chr11_-_61668486 0.697 NM_013881
Ulk2
Unc-51 like kinase 2 (C. elegans)
chr5_+_24191614 0.692 NM_016736
Nub1
negative regulator of ubiquitin-like proteins 1
chr1_+_62749850 0.691 NM_001077403
NM_001077404
NM_001077405
NM_001077406
NM_001077407
NM_010939
Nrp2





neuropilin 2





chrX_+_97972559 0.690 NM_001177780
Dlg3
discs, large homolog 3 (Drosophila)
chr5_+_108494692 0.687 NM_013827
Mtf2
metal response element binding transcription factor 2
chrX_+_12648604 0.681 NM_009481
Usp9x
ubiquitin specific peptidase 9, X chromosome
chr1_-_188529867 0.680 NM_009367
Tgfb2
transforming growth factor, beta 2
chrX_+_98835386 0.677 NM_139144
Ogt
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr9_-_86775154 0.673 NM_013669
Snap91
synaptosomal-associated protein 91
chr2_+_4322020 0.673 NM_001177843
Frmd4a
FERM domain containing 4A
chr9_-_117161564 0.671 NM_001172122
NM_001172123
NM_001172124
NM_001172126
NM_178660
Rbms3




RNA binding motif, single stranded interacting protein




chr16_-_22163264 0.664 NM_183029
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr15_-_79272478 0.662 NM_013767
Csnk1e
casein kinase 1, epsilon
chr5_-_136410488 0.661 NM_018871
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr14_+_13116681 0.655 NM_146051
NM_178141
3830406C13Rik

RIKEN cDNA 3830406C13 gene

chr16_-_67621054 0.655 NM_001145977
NM_178721
Cadm2

cell adhesion molecule 2

chr4_+_48598013 0.654 NM_021436
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr7_-_91558468 0.653 NM_007488
Arnt2
aryl hydrocarbon receptor nuclear translocator 2
chr5_+_99283433 0.648 NM_173404
Bmp3
bone morphogenetic protein 3
chr8_+_68141935 0.640 NM_001166372
March1
membrane-associated ring finger (C3HC4) 1
chr14_+_28435613 0.633 NM_177814
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr2_+_4073908 0.632 NM_172475
Frmd4a
FERM domain containing 4A
chr12_+_71926429 0.627 NM_028127
Frmd6
FERM domain containing 6
chr2_+_76244578 0.627 NM_145525
Osbpl6
oxysterol binding protein-like 6
chr1_+_138027943 0.626 NM_001039472
Kif21b
kinesin family member 21B
chr15_+_68758773 0.623 NM_010158
Khdrbs3
KH domain containing, RNA binding, signal transduction associated 3
chr2_-_69424085 0.622 NM_001081088
Lrp2
low density lipoprotein receptor-related protein 2
chr11_+_20991321 0.608 NM_023324
Peli1
pellino 1
chr17_+_26852581 0.607 NM_029870
A930001N09Rik
RIKEN cDNA A930001N09 gene
chr1_+_66221851 0.605 NM_001039934
NM_008632
Mtap2

microtubule-associated protein 2

chr6_+_143115732 0.598 NM_029250
Etnk1
ethanolamine kinase 1
chr4_+_34011567 0.589 NM_007726
Cnr1
cannabinoid receptor 1 (brain)
chr4_+_151552208 0.588 NM_133348
AU014716
Acot7
expressed sequence AU014716
acyl-CoA thioesterase 7
chr2_+_30093236 0.575 NM_177725
Lrrc8a
leucine rich repeat containing 8A
chr2_-_120676125 0.570 NM_001024856
NM_001024857
NM_080788
Ttbk2


tau tubulin kinase 2


chr2_+_132088974 0.560 NM_138651
Cds2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr13_-_54789148 0.559 NM_001146025
NM_001146026
NM_134064
Rnf44


ring finger protein 44


chr5_+_93696566 0.557 NM_007635
Ccng2
cyclin G2
chr2_+_160471623 0.555 NM_009408
Top1
topoisomerase (DNA) I
chr8_-_72644704 0.553 NM_007789
Ncan
neurocan
chr14_+_8930682 0.552 NM_145458
NM_178279
Pxk

PX domain containing serine/threonine kinase

chr4_-_125933482 0.544 NM_001145970
NM_144941
Mtap7d1

microtubule-associated protein 7 domain containing 1

chr7_-_13404178 0.542 NM_026046
Zfp329
zinc finger protein 329
chr3_-_65196395 0.540 NM_026155
Ssr3
signal sequence receptor, gamma
chr11_-_20731016 0.531 NM_173752
1110067D22Rik
RIKEN cDNA 1110067D22 gene
chr15_+_93228780 0.529 NM_001083114
NM_146062
NM_175363
Pphln1


periphilin 1


chr9_+_96159666 0.528 NM_001184710
NM_001184711
Tfdp2

transcription factor Dp 2

chr5_+_77403725 0.524 NM_025691
Srp72
signal recognition particle 72
chr3_-_79371600 0.523 NM_001162999
Fnip2
folliculin interacting protein 2
chr11_-_60988490 0.520 NM_001004143
Usp22
ubiquitin specific peptidase 22
chr12_-_88225714 0.511 NM_145836
6430527G18Rik
RIKEN cDNA 6430527G18 gene
chr2_+_61642509 0.510 NM_009322
Tbr1
T-box brain gene 1
chr1_-_107253245 0.507 NM_001160368
NM_178779
Rnf152

ring finger protein 152

chrX_+_162676870 0.506 NM_001177961
NM_001177962
NM_023122
Gpm6b


glycoprotein m6b


chr12_+_73637330 0.499 NM_026327
1810048J11Rik
RIKEN cDNA 1810048J11 gene
chr15_-_33617572 0.499 NM_001085421
Tspyl5
testis-specific protein, Y-encoded-like 5
chr5_-_68238654 0.495 NM_001038999
NM_009727
Atp8a1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr2_-_104656852 0.494 NM_001123327
Qser1
glutamine and serine rich 1
chr11_-_94183188 0.489 NM_026313
Luc7l3
LUC7-like 3 (S. cerevisiae)
chr2_+_119373442 0.486 NM_019769
1500003O03Rik
RIKEN cDNA 1500003O03 gene
chrX_-_102052460 0.486 NM_053206
Magee2
melanoma antigen, family E, 2
chrX_-_103207106 0.486 NM_001190409
NM_025952
Magt1

magnesium transporter 1

chr1_+_59969845 0.485 NM_001037725
Fam117b
family with sequence similarity 117, member B
chrX_+_98494487 0.485 NM_172932
Nlgn3
neuroligin 3
chr6_-_144997311 0.483 NM_001024468
Bcat1
branched chain aminotransferase 1, cytosolic
chr2_+_48805027 0.479 NM_029924
Mbd5
methyl-CpG binding domain protein 5
chr12_+_73543228 0.479 NM_001142729
Lrrc9
leucine rich repeat containing 9
chr4_-_15076093 0.476 NM_178617
Necab1
N-terminal EF-hand calcium binding protein 1
chr10_+_110601745 0.475 NM_001003717
NM_175489
Osbpl8

oxysterol binding protein-like 8

chr15_-_63891810 0.473 NM_144846
Fam49b
family with sequence similarity 49, member B
chr14_-_62058627 0.472 NM_008466
Kpna3
karyopherin (importin) alpha 3
chr3_-_116126932 0.471 NM_001080818
NM_001173553
Cdc14a

CDC14 cell division cycle 14 homolog A (S. cerevisiae)

chr2_-_130249983 0.471 NM_178762
Fam113a
family with sequence similarity 113, member A
chr3_-_146433200 0.468 NM_001164198
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr15_-_93167308 0.465 NM_024189
Yaf2
YY1 associated factor 2
chr5_-_123350242 0.463 NM_013910
Kdm2b
lysine (K)-specific demethylase 2B
chr17_-_29484848 0.461 NM_019880
Mtch1
mitochondrial carrier homolog 1 (C. elegans)
chr7_-_88092388 0.461 NM_019951
Sec11a
SEC11 homolog A (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
5.09 1.04e-06 GO:0007399 nervous system development
3.09 2.26e-06 GO:0007275 multicellular organismal development
2.94 3.52e-06 GO:0032502 developmental process
3.05 2.71e-05 GO:0048856 anatomical structure development
3.01 2.78e-04 GO:0048731 system development
3.94 3.52e-04 GO:0009653 anatomical structure morphogenesis
2.97 4.61e-03 GO:0048869 cellular developmental process
295.71 5.46e-03 GO:0021636 trigeminal nerve morphogenesis
2.02 6.47e-03 GO:0032501 multicellular organismal process
5.23 8.67e-03 GO:0040011 locomotion
2.90 1.18e-02 GO:0030154 cell differentiation
197.14 1.64e-02 GO:0021559 trigeminal nerve development
21.14 1.82e-02 GO:0050808 synapse organization
5.59 4.05e-02 GO:0006928 cellular component movement
6.46 4.76e-02 GO:0035295 tube development

Gene overrepresentation in compartment category:

enrichment p-value GO term description
7.12 1.20e-03 GO:0044456 synapse part
5.59 2.31e-03 GO:0045202 synapse
4.81 7.42e-03 GO:0043005 neuron projection

Gene overrepresentation in function category:

enrichment p-value GO term description
4.86 4.85e-04 GO:0001071 nucleic acid binding transcription factor activity
4.86 4.85e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
84.50 2.30e-02 GO:0017154 semaphorin receptor activity
4.22 2.45e-02 GO:0043565 sequence-specific DNA binding