Motif ID: AGCUUAU

Z-value: 0.637

Mature miRNA associated with seed AGCUUAU:

NamemiRBase Accession
mmu-miR-21 MIMAT0000530
mmu-miR-590-5p MIMAT0004895



Activity profile for motif AGCUUAU.

activity profile for motif AGCUUAU


Sorted Z-values histogram for motif AGCUUAU

Sorted Z-values for motif AGCUUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCUUAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr13_+_56710896 2.960 NM_009369
Tgfbi
transforming growth factor, beta induced
chr5_-_38215607 1.845 NM_010835
Msx1
homeobox, msh-like 1
chr18_+_56591785 1.733 NM_026240
Gramd3
GRAM domain containing 3
chr13_-_64254466 1.371 NM_175494
Zfp367
zinc finger protein 367
chr9_-_8004559 1.306 NM_001171147
NM_009534
Yap1

yes-associated protein 1

chrX_+_39503858 1.253 NM_021465
Stag2
stromal antigen 2
chr4_+_97444312 1.235 NM_001122953
NM_010905
Nfia

nuclear factor I/A

chr2_-_136942066 1.196 NM_013822
Jag1
jagged 1
chr13_-_112599181 1.160 NM_011945
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr6_+_88148657 0.993 NM_008090
Gata2
GATA binding protein 2
chr5_+_53981453 0.908 NM_009035
NM_001080927
Rbpj

recombination signal binding protein for immunoglobulin kappa J region

chr3_+_37538808 0.907 NM_011896
Spry1
sprouty homolog 1 (Drosophila)
chr2_+_3630729 0.879 NM_025626
Fam107b
family with sequence similarity 107, member B
chr18_+_75527015 0.864 NM_001042660
Smad7
MAD homolog 7 (Drosophila)
chr16_+_4594703 0.832 NM_031184
Glis2
GLIS family zinc finger 2
chr15_+_80629020 0.812 NM_177124
Tnrc6b
trinucleotide repeat containing 6b
chr6_-_39156706 0.785 NM_001033430
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr3_+_60305108 0.770 NM_020007
Mbnl1
muscleblind-like 1 (Drosophila)
chr11_+_60745534 0.744 NM_008928
Map2k3
mitogen-activated protein kinase kinase 3
chr15_+_80541675 0.733 NM_144812
Tnrc6b
trinucleotide repeat containing 6b
chr14_+_67254087 0.712 NM_013461
Adra1a
adrenergic receptor, alpha 1a
chr1_-_135975681 0.697 NM_007570
Btg2
B-cell translocation gene 2, anti-proliferative
chr11_+_59475986 0.696 NM_012027
NM_201245
Mprip

myosin phosphatase Rho interacting protein

chr5_-_103640272 0.685 NM_001081567
NM_009158
Mapk10

mitogen-activated protein kinase 10

chr5_-_64360058 0.676 NM_145923
Rell1
RELT-like 1
chr15_-_9070066 0.665 NM_013787
NM_145468
Skp2

S-phase kinase-associated protein 2 (p45)

chr6_-_144157971 0.653 NM_001113559
NM_011444
Sox5

SRY-box containing gene 5

chr4_-_19636000 0.625 NM_177327
Wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr10_+_53316720 0.574 NM_025541
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr2_-_148233853 0.572 NM_009378
Thbd
thrombomodulin
chr2_-_117168600 0.571 NM_011246
Rasgrp1
RAS guanyl releasing protein 1
chr9_-_42913797 0.558 NM_027144
Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
chr9_+_109778051 0.550 NM_007658
Cdc25a
cell division cycle 25 homolog A (S. pombe)
chr15_+_102300972 0.525 NM_001103165
NM_001103166
NM_001174073
NM_011042
Pcbp2



poly(rC) binding protein 2



chr5_-_135870365 0.517 NM_148932
Pom121
nuclear pore membrane protein 121
chr11_+_60230646 0.516 NM_025757
4933439F18Rik
RIKEN cDNA 4933439F18 gene
chr9_-_116084395 0.505 NM_009371
NM_029575
Tgfbr2

transforming growth factor, beta receptor II

chr13_-_102462584 0.473 NM_001024955
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr8_-_72877137 0.449 NM_001122829
NM_030680
Upf1

UPF1 regulator of nonsense transcripts homolog (yeast)

chr14_+_31832323 0.427 NM_001081251
Pbrm1
polybromo 1
chr7_+_73007017 0.409 NM_011048
Pcsk6
proprotein convertase subtilisin/kexin type 6
chr18_+_84257471 0.406 NM_146090
Zadh2
zinc binding alcohol dehydrogenase, domain containing 2
chr14_+_64562509 0.405 NM_011446
Sox7
SRY-box containing gene 7
chr1_-_184271729 0.393 NM_175127
Fbxo28
F-box protein 28
chr15_-_73015345 0.386 NM_153178
Eif2c2
eukaryotic translation initiation factor 2C, 2
chr15_+_100701068 0.383 NM_001077499
Scn8a
sodium channel, voltage-gated, type VIII, alpha
chr16_-_89960987 0.374 NM_009384
Tiam1
T-cell lymphoma invasion and metastasis 1
chr3_+_135101664 0.372 NM_025356
Ube2d3
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr11_-_20149322 0.368 NM_172260
Cep68
centrosomal protein 68
chr4_-_133523750 0.356 NM_016957
Hmgn2
high mobility group nucleosomal binding domain 2
chr5_+_123794456 0.352 NM_029850
Bcl7a
B-cell CLL/lymphoma 7A
chr6_-_71390592 0.347 NM_024288
Rmnd5a
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr17_-_51951378 0.338 NM_001163630
Satb1
special AT-rich sequence binding protein 1
chr17_-_51971946 0.324 NM_009122
Satb1
special AT-rich sequence binding protein 1
chr15_+_100766701 0.311 NM_011323
Scn8a
sodium channel, voltage-gated, type VIII, alpha
chr12_+_54349663 0.310 NM_013780
Npas3
neuronal PAS domain protein 3
chr10_+_85763156 0.276 NM_011595
Timp3
tissue inhibitor of metalloproteinase 3
chr4_+_122673318 0.276 NM_008506
Mycl1
v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)
chr9_-_70504934 0.275 NM_172772
Fam63b
family with sequence similarity 63, member B
chr4_+_43888373 0.267 NM_016678
Reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr8_-_88079169 0.259 NM_019794
Dnaja2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr19_+_7492081 0.239 NM_175381
2700081O15Rik
RIKEN cDNA 2700081O15 gene
chr2_+_109757803 0.237 NM_172671
Lgr4
leucine-rich repeat-containing G protein-coupled receptor 4
chr12_+_9581218 0.233 NM_011859
Osr1
odd-skipped related 1 (Drosophila)
chr8_-_36028698 0.232 NM_175091
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr2_+_113167862 0.231 NM_001043322
NM_010230
Fmn1

formin 1

chr19_+_6276885 0.230 NM_010119
Ehd1
EH-domain containing 1
chrX_+_39502588 0.229 NM_001077712
Stag2
stromal antigen 2
chr15_-_91022198 0.225 NM_011994
Abcd2
ATP-binding cassette, sub-family D (ALD), member 2
chr4_-_123089122 0.219 NM_001167918
D830031N03Rik
RIKEN cDNA D830031N03 gene
chr8_-_48799252 0.219 NM_172407
Cdkn2aip
CDKN2A interacting protein
chr3_-_55987612 0.217 NM_030595
Nbea
neurobeachin
chr3_+_94247220 0.216 NM_030116
Mrpl9
mitochondrial ribosomal protein L9
chr17_-_51972514 0.208 NM_001163632
Satb1
special AT-rich sequence binding protein 1
chr6_-_86476063 0.200 NM_011865
Pcbp1
poly(rC) binding protein 1
chr1_-_74170987 0.197 NM_027884
Tns1
tensin 1
chr17_+_25359526 0.187 NM_028789
Unkl
unkempt-like (Drosophila)
chr13_+_34967355 0.165 NM_013830
Prpf4b
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
chr11_-_100800603 0.163 NM_011486
NM_213659
NM_213660
Stat3


signal transducer and activator of transcription 3


chr1_-_17087821 0.157 NM_020604
Jph1
junctophilin 1
chr10_-_120416369 0.153 NM_001081193
Lemd3
LEM domain containing 3
chr2_+_59450080 0.152 NM_198294
Tanc1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr2_+_69735301 0.150 NM_001081548
NM_177783
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr2_-_152240762 0.141 NM_175126
Zcchc3
zinc finger, CCHC domain containing 3
chr8_-_114400574 0.140 NM_025781
Tmem170
transmembrane protein 170
chr11_-_82684653 0.139 NM_001007465
NM_001164569
NM_001164571
Rffl


ring finger and FYVE like domain containing protein


chr4_+_125781197 0.137 NM_001145827
NM_028800
Stk40

serine/threonine kinase 40

chr17_+_25325344 0.136 NM_001197024
Unkl
unkempt-like (Drosophila)
chr15_+_97938874 0.136 NM_001163487
Pfkm
phosphofructokinase, muscle
chr6_+_66846377 0.122 NM_001177556
NM_001177557
NM_001177559
NM_001177560
NM_025278
Gng12




guanine nucleotide binding protein (G protein), gamma 12




chr5_+_148242018 0.121 NM_028291
Pan3
PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr7_-_127039189 0.109 NM_001163703
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr5_+_102910409 0.106 NM_029270
NM_146161
Arhgap24

Rho GTPase activating protein 24

chr1_+_132613903 0.105 NM_178691
Yod1
YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae)
chr14_+_18493380 0.101 NM_001113417
Thrb
thyroid hormone receptor beta
chr3_+_34548916 0.099 NM_011443
Sox2
SRY-box containing gene 2
chr11_+_20991321 0.096 NM_023324
Peli1
pellino 1
chr14_-_21871647 0.088 NM_018829
Ap3m1
adaptor-related protein complex 3, mu 1 subunit
chr11_+_98657082 0.084 NM_028722
Msl1
male-specific lethal 1 homolog (Drosophila)
chr11_+_33947115 0.083 NM_010696
Lcp2
lymphocyte cytosolic protein 2
chr12_-_109241423 0.081 NM_001079883
NM_021399
Bcl11b

B-cell leukemia/lymphoma 11B

chr5_+_65928483 0.078 NM_016786
Ube2k
ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
chr6_-_126595818 0.076 NM_010595
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr3_+_128902822 0.073 NM_011098
NM_001042504
Pitx2

paired-like homeodomain transcription factor 2

chr5_-_46247789 0.068 NM_172153
Lcorl
ligand dependent nuclear receptor corepressor-like
chr3_+_97817440 0.067 NM_010928
Notch2
Notch gene homolog 2 (Drosophila)
chr7_-_127038916 0.067 NM_173408
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr10_+_42481292 0.059 NM_153055
Sec63
SEC63-like (S. cerevisiae)
chr9_-_70351520 0.054 NM_033604
Rnf111
ring finger 111
chr15_-_12522310 0.051 NM_001081064
Pdzd2
PDZ domain containing 2
chr6_+_134780207 0.050 NM_177687
Crebl2
cAMP responsive element binding protein-like 2
chr9_-_96531911 0.039 NM_053268
Rasa2
RAS p21 protein activator 2
chr6_+_8459595 0.034 NM_133236
Glcci1
glucocorticoid induced transcript 1
chr16_-_89818596 0.031 NM_001145887
Tiam1
T-cell lymphoma invasion and metastasis 1
chr17_+_8118823 0.028 NM_145968
Tagap
T-cell activation Rho GTPase-activating protein
chr2_-_58210162 0.026 NM_001111030
Acvr1c
activin A receptor, type IC
chr5_-_5694033 0.020 NM_001103156
NM_001103157
Steap2

six transmembrane epithelial antigen of prostate 2

chr19_-_29880498 0.017 NM_172836
9930021J03Rik
RIKEN cDNA 9930021J03 gene
chr6_-_126114938 0.014 NM_001164035
Ntf3
neurotrophin 3
chr8_-_109620413 0.012 NM_001083118
NM_009353
Terf2

telomeric repeat binding factor 2

chr3_-_115710131 0.008 NM_023214
Slc30a7
solute carrier family 30 (zinc transporter), member 7
chr12_+_84973146 0.002 NM_027349
AA645497
Rbm25
expressed sequence AA645497
RNA binding motif protein 25

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
11.20 2.03e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
34.11 5.57e-03 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
15.02 5.91e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
27.30 1.08e-02 GO:0043193 positive regulation of gene-specific transcription
5.24 1.57e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
11.40 1.74e-02 GO:0045893 positive regulation of transcription, DNA-dependent
5.12 1.81e-02 GO:0010556 regulation of macromolecule biosynthetic process
11.23 1.84e-02 GO:0051254 positive regulation of RNA metabolic process
4.87 2.39e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
10.47 2.42e-02 GO:0010628 positive regulation of gene expression
4.84 2.48e-02 GO:0031326 regulation of cellular biosynthetic process
4.82 2.54e-02 GO:0051171 regulation of nitrogen compound metabolic process
4.78 2.67e-02 GO:0009889 regulation of biosynthetic process
9.96 2.94e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
9.82 3.11e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
9.71 3.24e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
18.59 3.37e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
9.14 4.10e-02 GO:0031328 positive regulation of cellular biosynthetic process
8.96 4.42e-02 GO:0009891 positive regulation of biosynthetic process

Nothing significant found in compartment category.

Nothing significant found in function category.