Motif ID: AGUGCAA

Z-value: 0.815

Mature miRNA associated with seed AGUGCAA:

NamemiRBase Accession
mmu-miR-130a MIMAT0000141
mmu-miR-130b MIMAT0000387
mmu-miR-301a MIMAT0000379
mmu-miR-301b MIMAT0004186
mmu-miR-721 MIMAT0003515



Activity profile for motif AGUGCAA.

activity profile for motif AGUGCAA


Sorted Z-values histogram for motif AGUGCAA

Sorted Z-values for motif AGUGCAA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGUGCAA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr2_+_138104219 7.123 NM_145534
Btbd3
BTB (POZ) domain containing 3
chr2_-_79296732 6.194 NM_010894
Neurod1
neurogenic differentiation 1
chr4_+_97248556 4.895 NM_001122952
Nfia
D130039L10Rik
nuclear factor I/A
RIKEN cDNA D130039L10 gene
chr1_+_179374783 4.525 NM_001012330
Zfp238
zinc finger protein 238
chr6_+_108163089 4.076 NM_010585
Itpr1
inositol 1,4,5-triphosphate receptor 1
chr4_+_97444312 3.604 NM_001122953
NM_010905
Nfia

nuclear factor I/A

chr8_-_97220127 3.563 NM_026385
Pllp
plasma membrane proteolipid
chr15_+_40486577 3.340 NM_011766
Zfpm2
zinc finger protein, multitype 2
chr8_-_116372637 3.174 NM_172466
Adamts18
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr4_-_82151180 3.049 NM_001113209
NM_001113210
NM_008687
Nfib


nuclear factor I/B


chr8_-_70342105 3.011 NM_027626
Psd3
pleckstrin and Sec7 domain containing 3
chr4_-_25727109 2.922 NM_010243
Fut9
fucosyltransferase 9
chr6_-_113991945 2.673 NM_009723
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr6_-_113841356 2.566 NM_001036684
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr11_+_6963421 2.458 NM_009622
Adcy1
adenylate cyclase 1
chr10_-_49508472 2.419 NM_001111268
NM_010349
Grik2

glutamate receptor, ionotropic, kainate 2 (beta 2)

chr17_+_44215761 2.404 NM_032003
NM_001168620
Enpp5

ectonucleotide pyrophosphatase/phosphodiesterase 5

chr8_-_74195650 2.342 NM_001029873
Unc13a
unc-13 homolog A (C. elegans)
chr4_-_53172748 2.313 NM_013454
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr18_+_77424573 2.275 NM_013666
NM_153124
St8sia5

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5

chr3_-_125641429 2.253 NM_011674
Ugt8a
UDP galactosyltransferase 8A
chr9_-_107134182 2.180 NM_153413
Dock3
dedicator of cyto-kinesis 3
chr11_-_90252228 2.175 NM_172563
Hlf
hepatic leukemia factor
chr1_-_188529867 2.089 NM_009367
Tgfb2
transforming growth factor, beta 2
chr16_+_30599808 2.050 NM_177632
Fam43a
family with sequence similarity 43, member A
chr8_-_17535279 1.863 NM_053171
Csmd1
CUB and Sushi multiple domains 1
chr2_+_131735663 1.857 NM_011170
Prnp
prion protein
chr18_-_35374663 1.826 NM_178005
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr2_+_136539143 1.805 NM_011428
Snap25
synaptosomal-associated protein 25
chr7_-_71083734 1.689 NM_021366
Klf13
Kruppel-like factor 13
chr10_+_105907394 1.622 NM_177373
Ppfia2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr19_+_21346734 1.531 NM_009551
Zfand5
zinc finger, AN1-type domain 5
chr8_+_47556353 1.522 NM_007981
Acsl1
acyl-CoA synthetase long-chain family member 1
chr13_+_64263131 1.510 NM_019986
Habp4
hyaluronic acid binding protein 4
chr11_-_59778306 1.503 NM_009026
Rasd1
RAS, dexamethasone-induced 1
chr10_-_80889856 1.499 NM_008688
NM_026756
Nfic

nuclear factor I/C

chr11_-_106134024 1.494 NM_001130187
Smarcd2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr1_+_182260606 1.493 NM_001081175
Itpkb
inositol 1,4,5-trisphosphate 3-kinase B
chr4_+_107474842 1.444 NM_001080926
Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr4_-_86876328 1.422 NM_172426
Slc24a2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr2_+_181501718 1.380 NM_001171616
NM_008665
Myt1

myelin transcription factor 1

chr18_+_69504145 1.345 NM_013685
Tcf4
transcription factor 4
chr7_+_52419289 1.310 NM_182993
Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr14_+_45839391 1.298 NM_027518
Gpr137c
G protein-coupled receptor 137C
chr17_-_87846158 1.287 NM_007589
Calm2
calmodulin 2
chr11_-_20731016 1.270 NM_173752
1110067D22Rik
RIKEN cDNA 1110067D22 gene
chr18_-_23197156 1.260 NM_001161483
Nol4
nucleolar protein 4
chr17_-_67703726 1.245 NM_008984
Ptprm
protein tyrosine phosphatase, receptor type, M
chr19_+_32832002 1.243 NM_008960
Pten
phosphatase and tensin homolog
chr19_-_4397075 1.232 NM_001001984
Kdm2a
lysine (K)-specific demethylase 2A
chr2_-_167318313 1.229 NM_170756
Spata2
spermatogenesis associated 2
chr8_-_63433528 1.201 NM_173876
Clcn3
chloride channel 3
chr12_-_73337707 1.187 NM_001007596
Rtn1
reticulon 1
chr17_+_42452895 1.177 NM_028474
3110082D06Rik
RIKEN cDNA 3110082D06 gene
chr3_-_115417932 1.156 NM_007901
S1pr1
sphingosine-1-phosphate receptor 1
chr6_+_117118552 1.149 NM_001012477
NM_013655
NM_021704
Cxcl12


chemokine (C-X-C motif) ligand 12


chr11_+_87574041 1.109 NM_172449
Bzrap1
benzodiazepine receptor associated protein 1
chr2_-_144096253 1.094 NM_024225
Snx5
sorting nexin 5
chr5_+_31117077 1.079 NM_133350
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr8_+_123061308 1.031 NM_001145896
Gse1
genetic suppressor element 1
chr17_-_45823145 1.030 NM_198167
Tmem63b
transmembrane protein 63b
chr1_+_136543253 1.018 NM_009307
Syt2
synaptotagmin II
chr8_+_123012667 1.014 NM_198671
Gse1
genetic suppressor element 1
chr2_-_38142866 1.007 NM_146122
Dennd1a
DENN/MADD domain containing 1A
chr11_-_88725877 0.996 NM_001042541
Akap1
A kinase (PRKA) anchor protein 1
chr3_+_96361879 0.952 NM_001009935
NM_023719
Txnip

thioredoxin interacting protein

chr18_+_84257471 0.946 NM_146090
Zadh2
zinc binding alcohol dehydrogenase, domain containing 2
chr5_-_124482223 0.933 NM_177876
Vps37b
vacuolar protein sorting 37B (yeast)
chr6_+_86799460 0.929 NM_001040106
NM_177762
Aak1

AP2 associated kinase 1

chr18_+_63081977 0.923 NM_133237
Apcdd1
adenomatosis polyposis coli down-regulated 1
chr11_-_115948258 0.907 NM_016852
Wbp2
WW domain binding protein 2
chr11_-_119409041 0.894 NM_008730
Nptx1
neuronal pentraxin 1
chr7_-_116895708 0.883 NM_020050
Tmem9b
TMEM9 domain family, member B
chrX_-_119510890 0.883 NM_138742
Nap1l3
nucleosome assembly protein 1-like 3
chr2_+_71819264 0.865 NM_019688
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr4_+_34011567 0.858 NM_007726
Cnr1
cannabinoid receptor 1 (brain)
chr12_-_103943059 0.843 NM_172584
Itpk1
inositol 1,3,4-triphosphate 5/6 kinase
chr10_+_59740373 0.839 NM_001146120
NM_001146121
NM_001146122
NM_001146123
NM_011179
Psap




prosaposin




chr9_+_58430031 0.837 NM_009145
Nptn
neuroplastin
chr8_-_48374755 0.834 NM_001114311
Stox2
storkhead box 2
chr8_-_63462080 0.832 NM_007711
NM_173873
NM_173874
Clcn3


chloride channel 3


chr17_-_17761403 0.821 NM_172827
Lnpep
leucyl/cystinyl aminopeptidase
chr3_-_51364525 0.818 NM_080793
Setd7
SET domain containing (lysine methyltransferase) 7
chr9_-_116084395 0.814 NM_009371
NM_029575
Tgfbr2

transforming growth factor, beta receptor II

chr3_-_55987612 0.799 NM_030595
Nbea
neurobeachin
chr15_-_81688686 0.798 NM_020507
Tob2
transducer of ERBB2, 2
chr15_+_25552273 0.798 NM_019472
Myo10
myosin X
chr2_+_91490266 0.797 NM_001145902
Arhgap1
Rho GTPase activating protein 1
chr2_+_134611879 0.790 NM_001145830
NM_019677
Plcb1

phospholipase C, beta 1

chr1_+_6720087 0.777 NM_173868
St18
suppression of tumorigenicity 18
chr1_+_174271338 0.774 NM_001039484
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr10_-_75807976 0.765 NM_001081419
Dip2a
DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr15_-_57907967 0.761 NM_001042438
NM_009572
Zhx1

zinc fingers and homeoboxes 1

chr17_-_45686604 0.737 NM_001013749
Tmem151b
transmembrane protein 151B
chr5_-_149364353 0.726 NM_011908
Ubl3
ubiquitin-like 3
chr9_+_21229348 0.716 NM_001039520
Dnm2
dynamin 2
chr6_-_99616745 0.715 NM_025829
Eif4e3
eukaryotic translation initiation factor 4E member 3
chr12_+_3426883 0.701 NM_172421
Asxl2
additional sex combs like 2 (Drosophila)
chr14_-_32249046 0.698 NM_011894
Sh3bp5
SH3-domain binding protein 5 (BTK-associated)
chr5_-_63157309 0.692 NM_178407
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_+_103284200 0.683 NM_153505
Nckap1l
NCK associated protein 1 like
chr1_-_39535525 0.679 NM_018775
Tbc1d8
TBC1 domain family, member 8
chr8_-_70498472 0.675 NM_177698
Psd3
pleckstrin and Sec7 domain containing 3
chr6_-_116143380 0.660 NM_177412
Tmcc1
transmembrane and coiled coil domains 1
chr13_+_97312572 0.658 NM_001164222
NM_023420
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr3_+_60305108 0.655 NM_020007
Mbnl1
muscleblind-like 1 (Drosophila)
chr19_-_46401618 0.650 NM_028627
Psd
pleckstrin and Sec7 domain containing
chr16_-_17722915 0.634 NM_001040683
NM_033609
Med15

mediator complex subunit 15

chr14_-_46149660 0.628 NM_146054
Fermt2
fermitin family homolog 2 (Drosophila)
chr15_-_38944199 0.627 NM_172402
Slc25a32
solute carrier family 25, member 32
chr18_+_4634926 0.615 NM_001081963
9430020K01Rik
RIKEN cDNA 9430020K01 gene
chr3_+_152009436 0.611 NM_001076676
NM_133247
Usp33

ubiquitin specific peptidase 33

chr1_-_24594228 0.609 NM_007733
Col19a1
collagen, type XIX, alpha 1
chr6_-_58974400 0.609 NM_153574
Fam13a
family with sequence similarity 13, member A
chr18_-_23200150 0.607 NM_199024
Nol4
nucleolar protein 4
chr15_-_101966611 0.602 NM_001033277
Spryd3
SPRY domain containing 3
chr7_+_127245860 0.583 NM_145586
Tmem159
transmembrane protein 159
chr2_-_167174531 0.574 NM_019835
B4galt5
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
chr8_+_63111621 0.567 NM_027756
Mfap3l
microfibrillar-associated protein 3-like
chr4_-_140634151 0.561 NM_025383
Necap2
NECAP endocytosis associated 2
chr9_-_42913797 0.561 NM_027144
Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
chr11_-_106128935 0.546 NM_031878
Smarcd2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr9_+_30838224 0.544 NM_001115130
NM_172765
Zbtb44

zinc finger and BTB domain containing 44

chr13_-_105844882 0.540 NM_029879
Rgs7bp
regulator of G-protein signalling 7 binding protein
chrX_-_103124651 0.534 NM_009530
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr11_+_69579376 0.533 NM_029348
Zbtb4
zinc finger and BTB domain containing 4
chr15_+_80541675 0.529 NM_144812
Tnrc6b
trinucleotide repeat containing 6b
chr8_+_41509109 0.517 NM_178395
Zdhhc2
zinc finger, DHHC domain containing 2
chr10_+_40069113 0.513 NM_001168304
NM_198164
Cdk19

cyclin-dependent kinase 19

chr13_+_113254277 0.504 NM_010560
Il6st
interleukin 6 signal transducer
chr16_-_91597886 0.494 NM_030018
Tmem50b
transmembrane protein 50B
chr7_-_112781902 0.494 NM_018880
Trim3
tripartite motif-containing 3
chr4_+_102787069 0.485 NM_027696
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr5_-_74038829 0.484 NM_011890
Sgcb
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr5_+_75971011 0.476 NM_001122733
NM_021099
Kit

kit oncogene

chr17_-_66426361 0.470 NM_001025572
Ankrd12
ankyrin repeat domain 12
chr14_-_78936606 0.457 NM_001164503
Akap11
A kinase (PRKA) anchor protein 11
chr14_+_8930682 0.457 NM_145458
NM_178279
Pxk

PX domain containing serine/threonine kinase

chr3_-_152003317 0.440 NM_001162375
NM_174868
Fam73a

family with sequence similarity 73, member A

chr7_-_17200285 0.440 NM_172739
Grlf1
glucocorticoid receptor DNA binding factor 1
chr5_-_25004598 0.431 NM_001081383
Mll3
myeloid/lymphoid or mixed-lineage leukemia 3
chr4_+_109015660 0.429 NM_001159964
Eps15
epidermal growth factor receptor pathway substrate 15
chr1_-_163061538 0.425 NM_001039482
Klhl20
kelch-like 20 (Drosophila)
chr11_+_97524725 0.422 NM_139311
Mllt6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr8_-_37676995 0.418 NM_015802
Dlc1
deleted in liver cancer 1
chr11_-_103128675 0.415 NM_016896
Map3k14
mitogen-activated protein kinase kinase kinase 14
chr2_+_112219335 0.413 NM_024254
2410042D21Rik
RIKEN cDNA 2410042D21 gene
chrX_+_50341236 0.409 NM_013556
Hprt
hypoxanthine guanine phosphoribosyl transferase
chr13_-_19711409 0.405 NM_134065
Epdr1
ependymin related protein 1 (zebrafish)
chr4_-_126106749 0.405 NM_153402
Eif2c3
eukaryotic translation initiation factor 2C, 3
chr4_+_101091913 0.405 NM_001177605
NM_001177604
Ak4

adenylate kinase 4

chr6_+_143115732 0.401 NM_029250
Etnk1
ethanolamine kinase 1
chr1_+_89652645 0.397 NM_029846
Atg16l1
autophagy-related 16-like 1 (yeast)
chr17_-_66868909 0.395 NM_024448
Rab12
RAB12, member RAS oncogene family
chr10_-_20880559 0.395 NM_001198914
NM_010848
Myb

myeloblastosis oncogene

chr11_+_53583515 0.384 NM_001159393
NM_008390
Irf1

interferon regulatory factor 1

chr7_-_125635435 0.379 NM_001033380
Itpripl2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr13_+_81022644 0.376 NM_001042591
Arrdc3
arrestin domain containing 3
chr18_-_38760921 0.373 NM_011898
Spry4
sprouty homolog 4 (Drosophila)
chr10_+_13686174 0.368 NM_010437
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr5_-_3803095 0.366 NM_001003909
Ankib1
ankyrin repeat and IBR domain containing 1
chr5_-_92512486 0.362 NM_001080794
NM_001080796
G3bp2

GTPase activating protein (SH3 domain) binding protein 2

chr16_+_33380860 0.352 NM_011749
Zfp148
zinc finger protein 148
chr3_-_9610062 0.350 NM_133218
Zfp704
zinc finger protein 704
chr6_+_49269351 0.348 NM_175098
Ccdc126
coiled-coil domain containing 126
chr5_-_53604673 0.346 NM_172710
Sel1l3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr5_-_31597792 0.342 NM_022424
Fndc4
fibronectin type III domain containing 4
chr10_+_39089594 0.339 NM_001122892
NM_001122893
NM_008054
Fyn


Fyn proto-oncogene


chr11_-_28484265 0.339 NM_001166661
NM_001166662
NM_181577
Ccdc85a


coiled-coil domain containing 85A


chr6_-_71390592 0.337 NM_024288
Rmnd5a
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr4_+_108292534 0.335 NM_177045
Cc2d1b
coiled-coil and C2 domain containing 1B
chr12_+_112812710 0.318 NM_021516
NM_022801
Mark3

MAP/microtubule affinity-regulating kinase 3

chr11_+_52045464 0.312 NM_011543
Skp1a
S-phase kinase-associated protein 1A
chr2_+_80478960 0.312 NM_027091
Nup35
nucleoporin 35
chr14_-_27783615 0.303 NM_145221
Appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr12_+_81891479 0.300 NM_178682
4933426M11Rik
RIKEN cDNA 4933426M11 gene
chr4_-_94269846 0.298 NM_172695
Plaa
phospholipase A2, activating protein
chr5_-_124875921 0.292 NM_001081203
Sbno1
sno, strawberry notch homolog 1 (Drosophila)
chrX_+_100551808 0.290 NM_009767
Chic1
cysteine-rich hydrophobic domain 1
chr10_-_92773778 0.288 NM_013508
Elk3
ELK3, member of ETS oncogene family
chr2_-_160192799 0.287 NM_010658
Mafb
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr11_-_61668486 0.287 NM_013881
Ulk2
Unc-51 like kinase 2 (C. elegans)
chr2_+_49307005 0.285 NM_172663
Epc2
enhancer of polycomb homolog 2 (Drosophila)
chr6_-_94650118 0.282 NM_008377
Lrig1
leucine-rich repeats and immunoglobulin-like domains 1
chr18_-_84255781 0.280 NM_001081300
Tshz1
teashirt zinc finger family member 1
chr10_+_114822009 0.279 NM_001033261
Zfc3h1
zinc finger, C3H1-type containing
chr2_-_173102033 0.278 NM_022995
Pmepa1
prostate transmembrane protein, androgen induced 1
chr5_+_102194126 0.278 NM_173370
Cds1
CDP-diacylglycerol synthase 1
chr3_-_94386590 0.276 NM_001082484
NM_029721
Snx27

sorting nexin family member 27

chr8_-_26311823 0.273 NM_177089
NM_199323
Tacc1

transforming, acidic coiled-coil containing protein 1

chrX_+_158154967 0.271 NM_001103367
Rai2
retinoic acid induced 2
chr17_-_10512217 0.271 NM_001159516
NM_001159517
NM_021881
Qk


quaking


chr3_-_88229007 0.268 NM_001145876
NM_001145877
NM_178696
Slc25a44


solute carrier family 25, member 44


chr13_-_64254466 0.266 NM_175494
Zfp367
zinc finger protein 367
chr2_-_25978328 0.261 NM_026495
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr14_+_49791899 0.260 NM_001081430
Naa30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr6_-_119798116 0.256 NM_053204
NM_178085
Erc1

ELKS/RAB6-interacting/CAST family member 1

chr18_+_11816327 0.246 NM_001081223
Rbbp8
retinoblastoma binding protein 8
chr2_+_57090707 0.244 NM_010274
Gpd2
glycerol phosphate dehydrogenase 2, mitochondrial
chr18_+_14941735 0.241 NM_001100449
Taf4b
TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
30.93 2.78e-04 GO:0007613 memory
22.10 1.51e-03 GO:0048167 regulation of synaptic plasticity
5.85 3.15e-03 GO:0048878 chemical homeostasis
5.51 5.32e-03 GO:0007154 cell communication
7.43 5.32e-03 GO:0007610 behavior
63.78 6.58e-03 GO:0007616 long-term memory
4.49 1.25e-02 GO:0042592 homeostatic process
6.52 1.36e-02 GO:0006873 cellular ion homeostasis
6.36 1.63e-02 GO:0055082 cellular chemical homeostasis
13.40 1.74e-02 GO:0007611 learning or memory
12.61 2.33e-02 GO:0050890 cognition
5.97 2.55e-02 GO:0050801 ion homeostasis
39.25 2.99e-02 GO:0035249 synaptic transmission, glutamatergic
3.05 3.36e-02 GO:0065008 regulation of biological quality
3.70 3.41e-02 GO:0007399 nervous system development
34.02 4.64e-02 GO:0050805 negative regulation of synaptic transmission

Gene overrepresentation in compartment category:

enrichment p-value GO term description
4.79 8.88e-06 GO:0000267 cell fraction
5.60 1.00e-05 GO:0005624 membrane fraction
5.35 1.76e-05 GO:0005626 insoluble fraction
3.56 1.01e-04 GO:0044459 plasma membrane part
12.68 1.13e-04 GO:0045121 membrane raft
6.43 8.46e-04 GO:0045202 synapse
12.52 4.50e-03 GO:0019717 synaptosome
7.16 4.68e-03 GO:0044456 synapse part
2.27 4.86e-03 GO:0005886 plasma membrane
5.03 5.85e-03 GO:0030054 cell junction
2.22 6.76e-03 GO:0071944 cell periphery
9.84 1.40e-02 GO:0012506 vesicle membrane

Gene overrepresentation in function category:

enrichment p-value GO term description
14.80 1.61e-02 GO:0030165 PDZ domain binding
24.31 2.68e-02 GO:0000149 SNARE binding
4.11 3.06e-02 GO:0022891 substrate-specific transmembrane transporter activity