Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 2.057

Transcription factors associated with ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2:

NameEntrezDescription
Arnt 11863 aryl hydrocarbon receptor nuclear translocator
Arnt2 11864 aryl hydrocarbon receptor nuclear translocator 2
Bhlhe40 20893 basic helix-loop-helix family, member e40
Max 17187 Max protein
Myc 17869 myelocytomatosis oncogene
Usf1 22278 upstream transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Bhlhe40chr6_+_108610606-0.853.3e-11Click!
Arnt2chr7_-_915584070.821.0e-09Click!
Usf1chr1_+_1733414380.767.4e-08Click!
Mycchr15_+_61817102-0.651.5e-05Click!
Arntchr3_+_95238406-0.261.2e-01Click!
Maxchr12_-_78063011-0.173.1e-01Click!


Activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2.

activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2


Sorted Z-values histogram for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Sorted Z-values for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr10_+_126500607 28.256 NM_009870
Cdk4
cyclin-dependent kinase 4
chr12_+_3891743 21.788 NM_153743
Dnmt3a
DNA methyltransferase 3A
chr17_-_12962478 18.099 NM_010515
Igf2r
insulin-like growth factor 2 receptor
chr5_+_28492235 17.738 NM_010134
En2
engrailed 2
chr11_-_95867076 16.401 NM_009951
Igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr13_+_73901101 14.684 NM_011390
Slc12a7
solute carrier family 12, member 7
chr11_+_69814046 12.123 NM_007888
Dvl2
dishevelled 2, dsh homolog (Drosophila)
chr19_-_4201541 11.817 NM_011237
Rad9
RAD9 homolog (S. pombe)
chr6_-_49164469 11.148 Igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr14_+_51544629 11.003 NM_009687
Apex1
apurinic/apyrimidinic endonuclease 1
chr9_+_21172314 10.792 NM_001042707
NM_001042708
NM_001042709
NM_010561
Ilf3



interleukin enhancer binding factor 3



chr16_+_35770488 10.166 Hspbap1
Hspb associated protein 1
chr5_-_138721164 10.135 NM_172412
Gpc2
glypican 2 (cerebroglycan)
chr2_+_30141908 9.864 NM_198304
Nup188
nucleoporin 188
chr3_-_89856250 9.823 NM_001165983
NM_001165985
NM_001165987
NM_028475
NM_153489
NM_001165984
NM_001165986
NM_001165988
Ubap2l







ubiquitin associated protein 2-like







chr16_+_35770431 9.822 NM_175111
Hspbap1
Hspb associated protein 1
chr2_+_121275069 9.536 Serf2
small EDRK-rich factor 2
chr9_+_21216277 9.382 NM_021888
Qtrt1
queuine tRNA-ribosyltransferase 1
chr7_-_52384104 8.937 NM_009438
Rpl13a
ribosomal protein L13A
chr2_+_160471623 8.832 NM_009408
Top1
topoisomerase (DNA) I
chr4_-_41222121 8.720 NM_026872
Ubap2
ubiquitin-associated protein 2
chr13_-_72101161 8.674 NM_010573
Irx1
Iroquois related homeobox 1 (Drosophila)
chr1_+_168184269 8.211 NM_001164528
Ildr2
immunoglobulin-like domain containing receptor 2
chr4_-_34830178 8.204 NM_013889
Zfp292
zinc finger protein 292
chr16_-_5049936 8.039 Glyr1
glyoxylate reductase 1 homolog (Arabidopsis)
chr4_+_48598013 7.919 NM_021436
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr11_-_86621074 7.905 Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr4_-_86315874 7.689 NM_007408
Plin2
perilipin 2
chr3_+_67386633 7.560 NM_025813
Mfsd1
major facilitator superfamily domain containing 1
chr1_+_134212642 7.492 NM_001195025
NM_028778
Nuak2

NUAK family, SNF1-like kinase, 2

chr12_-_28027541 7.460 NM_009234
Sox11
SRY-box containing gene 11
chr15_+_59205752 7.318 NM_001164604
NM_026746
Nsmce2

non-SMC element 2 homolog (MMS21, S. cerevisiae)

chr18_-_6135924 7.318 NM_001039692
NM_029277
Arhgap12

Rho GTPase activating protein 12

chr12_-_103196366 7.231 NM_001167914
NM_029705
Atxn3

ataxin 3

chr11_+_83777922 7.220 NM_001115009
NM_194341
Synrg

synergin, gamma

chr2_+_25036276 7.212 NM_025980
Nrarp
Notch-regulated ankyrin repeat protein
chr2_+_75497282 7.212 NM_053263
NM_146130
NM_198090
Hnrnpa3


Gm6793
heterogeneous nuclear ribonucleoprotein A3


heterogeneous nuclear ribonucleoprotein A3 pseudogene
chr5_+_30431701 7.211 NM_001167879
Fam59b
family with sequence similarity 59, member B
chr5_+_145016060 6.932 NM_018772
Bri3
brain protein I3
chr2_+_158620555 6.932 NM_145742
Dhx35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr1_-_127808723 6.906 Lypd1
Ly6/Plaur domain containing 1
chr13_-_81772121 6.898 NM_054053
Gpr98
G protein-coupled receptor 98
chr6_-_38249209 6.854 NM_172467
Zc3hav1l
zinc finger CCCH-type, antiviral 1-like
chr4_-_142889372 6.829 NM_010329
Pdpn
podoplanin
chr18_+_23910833 6.680 NM_001162942
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr6_-_77929543 6.657 Ctnna2
catenin (cadherin associated protein), alpha 2
chr6_-_77929685 6.573 Ctnna2
catenin (cadherin associated protein), alpha 2
chr17_-_13898366 6.551 NM_022311
Tcte2
2700054A10Rik
t-complex-associated testis expressed 2
RIKEN cDNA 2700054A10 gene
chr14_-_51544497 6.519 NM_133676
Osgep
O-sialoglycoprotein endopeptidase
chr12_-_3426640 6.307 1110002L01Rik
RIKEN cDNA 1110002L01 gene
chr7_-_150646883 6.267 NM_001161624
NM_009876
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr1_-_130488785 6.164 NM_009911
Cxcr4
chemokine (C-X-C motif) receptor 4
chr15_-_98764960 6.065 Tuba1b
tubulin, alpha 1B
chr6_+_7505070 5.977 NM_009311
Tac1
tachykinin 1
chr7_+_152082435 5.953 NM_008003
Fgf15
fibroblast growth factor 15
chr5_-_92566671 5.952


chr18_-_6135887 5.942 Arhgap12
Rho GTPase activating protein 12
chr3_+_40439675 5.939 NM_175515
Intu
inturned planar cell polarity effector homolog (Drosophila)
chr17_-_35137690 5.934 D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr17_+_6106858 5.852 Tulp4
tubby like protein 4
chr19_-_4615661 5.825 NM_153388
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr3_-_89577134 5.821 4632404H12Rik
RIKEN cDNA 4632404H12 gene
chr15_-_59205688 5.805 NM_153548
E430025E21Rik
RIKEN cDNA E430025E21 gene
chr1_-_55144637 5.776 Hspd1
heat shock protein 1 (chaperonin)
chr12_-_32746061 5.752 NM_011158
Prkar2b
protein kinase, cAMP dependent regulatory, type II beta
chr17_+_6106857 5.752 Tulp4
tubby like protein 4
chr3_+_89856713 5.718 NM_025762
NM_027500
4933434E20Rik

RIKEN cDNA 4933434E20 gene

chr10_-_62486581 5.711 NM_001079824
Hnrnph3
D10Bwg1070e
heterogeneous nuclear ribonucleoprotein H3
DNA segment, Chr 10, Brigham & Women's Genetics 1070 expressed
chr16_+_94592373 5.693 Ttc3
tetratricopeptide repeat domain 3
chr1_+_89223558 5.679 NM_146112
NM_001110212
Gigyf2

GRB10 interacting GYF protein 2

chr9_-_63605917 5.633 Smad3
MAD homolog 3 (Drosophila)
chr3_-_107889507 5.568 NM_028779
Ampd2
adenosine monophosphate deaminase 2
chr2_+_160471695 5.516 Top1
topoisomerase (DNA) I
chr11_-_100621034 5.434 NM_001081194
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr6_-_128312829 5.389 5930416I19Rik
RIKEN cDNA 5930416I19 gene
chrX_+_78316003 5.384 Tmem47
transmembrane protein 47
chr17_-_33822327 5.379 NM_001109913
NM_029804
Hnrnpm

heterogeneous nuclear ribonucleoprotein M

chr17_-_25097542 5.361 NM_198937
Hn1l
hematological and neurological expressed 1-like
chr3_+_102862151 5.343 NM_010937
Nras
neuroblastoma ras oncogene
chr9_-_106789330 5.342 NM_175402
Rbm15b
RNA binding motif protein 15B
chr13_-_54789148 5.268 NM_001146025
NM_001146026
NM_134064
Rnf44


ring finger protein 44


chr14_-_68742863 5.252 Nefm
neurofilament, medium polypeptide
chr1_-_91827726 5.200 NM_010262
Gbx2
gastrulation brain homeobox 2
chr16_+_20672847 5.177 Eif4g1
eukaryotic translation initiation factor 4, gamma 1
chr11_-_77978936 5.137 NM_009423
Traf4
TNF receptor associated factor 4
chr1_+_168309297 5.136 NM_030245
Tada1
transcriptional adaptor 1
chr2_-_102291924 5.130 NM_010218
Fjx1
four jointed box 1 (Drosophila)
chr18_+_76401531 5.129 NM_010754
Smad2
MAD homolog 2 (Drosophila)
chr12_+_106692053 5.117 D430019H16Rik
RIKEN cDNA D430019H16 gene
chr4_+_147413185 5.091 NM_010840
Mthfr
5,10-methylenetetrahydrofolate reductase
chr10_+_36694322 5.074 NM_008229
Hdac2
histone deacetylase 2
chr16_-_5204036 5.062 Nagpa
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr3_+_152058937 5.056 NM_001080755
Zzz3
zinc finger, ZZ domain containing 3
chr10_-_5913894 4.998 NM_024261
1700052N19Rik
RIKEN cDNA 1700052N19 gene
chr4_-_45421590 4.983 NM_001009949
Mcart1
mitochondrial carrier triple repeat 1
chr19_-_60866516 4.983 NM_010123
Eif3a
eukaryotic translation initiation factor 3, subunit A
chr1_+_154613763 4.954 Arpc5
actin related protein 2/3 complex, subunit 5
chr17_+_29169612 4.953 Srsf3
serine/arginine-rich splicing factor 3
chr6_-_88848650 4.910 NM_008564
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr9_+_108241599 4.853 NM_008160
Gpx1
glutathione peroxidase 1
chr4_-_120887671 4.847 Rlf
rearranged L-myc fusion sequence
chr10_-_62801726 4.817 NM_001159590
NM_019812
NM_001159589
Sirt1


sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)


chr1_-_158135155 4.740 NM_177838
Fam163a
family with sequence similarity 163, member A
chr1_+_63223396 4.667 NM_018796
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr10_-_17742931 4.646 NM_028440
3110003A17Rik
RIKEN cDNA 3110003A17 gene
chr15_-_10644312 4.644 NM_001166408
Rai14
retinoic acid induced 14
chr13_+_21272015 4.635 Trim27
tripartite motif-containing 27
chr7_-_52241669 4.605 NM_019830
Prmt1
protein arginine N-methyltransferase 1
chr10_-_61949345 4.582 NM_001113355
NM_133672
Vps26a

vacuolar protein sorting 26 homolog A (yeast)

chr9_-_44169716 4.574 NM_027889
Vps11
vacuolar protein sorting 11 (yeast)
chr14_-_51544484 4.568 Osgep
O-sialoglycoprotein endopeptidase
chr4_-_108506131 4.566 NM_027453
Btf3l4
basic transcription factor 3-like 4
chr2_+_68699498 4.500 NM_172856
Lass6
LAG1 homolog, ceramide synthase 6
chr9_-_59598416 4.491 NM_001172068
NM_001172069
NM_001172070
NM_001172071
NM_027838
Senp8




SUMO/sentrin specific peptidase 8




chr1_-_12980994 4.385 NM_172841
Slco5a1
solute carrier organic anion transporter family, member 5A1
chr14_+_31832374 4.362 Pbrm1
polybromo 1
chr6_-_6167113 4.339 NM_001177572
NM_015829
Slc25a13

solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13

chr7_-_54051038 4.321 Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr13_-_54789064 4.231 Rnf44
ring finger protein 44
chr7_+_104936996 4.187 Pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr10_+_12810593 4.175 NM_009538
Plagl1
pleiomorphic adenoma gene-like 1
chr17_+_35137995 4.115 Vars
valyl-tRNA synthetase
chr16_-_18248701 4.058 NM_011239
Ranbp1
RAN binding protein 1
chr7_-_97278443 4.058 2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr1_-_55144687 4.042 NM_010477
Hspd1
heat shock protein 1 (chaperonin)
chr4_+_88783273 4.036 NM_024433
Mtap
methylthioadenosine phosphorylase
chr4_-_131631150 4.035 Epb4.1
erythrocyte protein band 4.1
chr7_+_104845148 4.019 NM_023671
Clns1a
chloride channel, nucleotide-sensitive, 1A
chr7_+_97278722 3.996 NM_146194
Picalm
phosphatidylinositol binding clathrin assembly protein
chr1_+_174412343 3.985 NM_001145800
NM_033608
Igsf9

immunoglobulin superfamily, member 9

chr11_-_86621130 3.967 NM_026191
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr4_-_48486214 3.948 NM_172304
Tex10
testis expressed gene 10
chr1_-_75139207 3.933 1810031K17Rik
RIKEN cDNA 1810031K17 gene
chr16_-_96349292 3.925 NM_008251
Hmgn1
high mobility group nucleosomal binding domain 1
chr9_+_54997159 3.903 NM_180600
Ube2q2
ubiquitin-conjugating enzyme E2Q (putative) 2
chr10_+_5914137 3.900 NM_025343
Rmnd1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chrX_-_6765768 3.892 NM_016691
Clcn5
chloride channel 5
chr2_-_71384748 3.829 NM_010054
Dlx2
distal-less homeobox 2
chr17_+_35137851 3.770 NM_011690
Vars
valyl-tRNA synthetase
chr4_+_21858472 3.765 NM_175234
6230409E13Rik
RIKEN cDNA 6230409E13 gene
chr2_-_28771940 3.758 NM_019446
NM_001164186
Barhl1

BarH-like 1 (Drosophila)

chr4_+_124334876 3.741 NM_011141
Pou3f1
POU domain, class 3, transcription factor 1
chr14_-_104921839 3.737 NM_026047
Rnf219
ring finger protein 219
chr2_-_74416925 3.721 NM_001110209
NM_027133
Lnp

limb and neural patterns

chr5_+_147042806 3.712 Cdk8
cyclin-dependent kinase 8
chr8_-_122099061 3.710 Hsdl1
hydroxysteroid dehydrogenase like 1
chr4_-_147462051 3.693 NM_009642
Agtrap
angiotensin II, type I receptor-associated protein
chr11_+_74644479 3.683 Mnt
max binding protein
chr4_+_132091462 3.630 NM_172400
Dnajc8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr16_+_5050149 3.613 NM_026666
Ubn1
ubinuclein 1
chrX_-_131343508 3.604 Armcx2
armadillo repeat containing, X-linked 2
chr4_-_136604609 3.597 NM_198248
Zbtb40
zinc finger and BTB domain containing 40
chr14_-_70843185 3.584 NM_025945
Polr3d
polymerase (RNA) III (DNA directed) polypeptide D
chr11_+_44332426 3.580 NM_028862
Rnf145
ring finger protein 145
chr7_+_54051432 3.562 NM_008186
Gtf2h1
general transcription factor II H, polypeptide 1
chr5_-_149806774 3.544 5930430L01Rik
RIKEN cDNA 5930430L01 gene
chr1_+_59741800 3.539 NM_018868
Nop58
NOP58 ribonucleoprotein homolog (yeast)
chr1_-_127808790 3.538 NM_145100
Lypd1
Ly6/Plaur domain containing 1
chr11_+_117193732 3.514


chr12_-_104116615 3.512 NM_172806
Btbd7
BTB (POZ) domain containing 7
chr11_-_102091406 3.512 NM_001077696
NM_010412
Hdac5

histone deacetylase 5

chr17_+_22561188 3.511 NM_198003
Zfp946
zinc finger protein 946
chr4_+_130125551 3.477 Nkain1
Na+/K+ transporting ATPase interacting 1
chr1_+_5073161 3.463 NM_133826
Atp6v1h
ATPase, H+ transporting, lysosomal V1 subunit H
chr10_+_43988192 3.453 Atg5
autophagy-related 5 (yeast)
chr13_-_54788995 3.447 Rnf44
ring finger protein 44
chr11_-_93746982 3.374 Utp18
UTP18, small subunit (SSU) processome component, homolog (yeast)
chrX_+_131252542 3.365 Armcx1
armadillo repeat containing, X-linked 1
chr1_+_121422719 3.364 NM_146103
Tmem185b
transmembrane protein 185B
chr2_-_155299483 3.360 Ncoa6
nuclear receptor coactivator 6
chr2_-_73730605 3.359 NM_001025093
NM_009715
Atf2

activating transcription factor 2

chr14_+_59820064 3.341 NM_027764
Rcbtb1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr1_+_50984361 3.339 NM_019790
Tmeff2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr11_-_97643692 3.332 Rpl23
ribosomal protein L23
chr3_+_107081927 3.302 Hbxip
hepatitis B virus x interacting protein
chr13_+_91062722 3.301 NM_024175
Rps23
ribosomal protein S23
chr17_-_85189859 3.294 Lrpprc
leucine-rich PPR-motif containing
chr12_-_55963776 3.285 NM_007688
Cfl2
cofilin 2, muscle
chr10_+_61111331 3.283 NM_026438
Ppa1
pyrophosphatase (inorganic) 1
chrX_+_103222548 3.258 NM_001109757
NM_009726
Atp7a

ATPase, Cu++ transporting, alpha polypeptide

chr10_-_117183413 3.257 NM_029875
Slc35e3
solute carrier family 35, member E3
chr12_-_36883307 3.251 NM_025840
Bzw2
basic leucine zipper and W2 domains 2
chr7_-_27981077 3.242 NM_015782
Snrpa
small nuclear ribonucleoprotein polypeptide A
chr1_+_55145132 3.238 Hspe1
heat shock protein 1 (chaperonin 10)
chr5_+_77380332 3.236 NM_025939
Paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
chr11_+_17111895 3.230 NM_178909
Wdr92
WD repeat domain 92
chrX_-_149471740 3.224 NM_023788
Mageh1
melanoma antigen, family H, 1
chr11_-_102742230 3.221 NM_001109995
NM_011431
Eftud2

elongation factor Tu GTP binding domain containing 2

chr2_-_144096518 3.190 Snx5
sorting nexin 5
chr6_+_116287992 3.189 March8
membrane-associated ring finger (C3HC4) 8
chr5_-_124875507 3.187 Sbno1
sno, strawberry notch homolog 1 (Drosophila)
chr11_-_97049143 3.186 Kpnb1
karyopherin (importin) beta 1
chr11_+_70658271 3.170 Rabep1
rabaptin, RAB GTPase binding effector protein 1
chr2_+_90780665 3.149 Celf1
CUGBP, Elav-like family member 1
chr2_+_152495244 3.136 H13
histocompatibility 13
chr5_-_138613028 3.133 NM_008568
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr12_+_17551771 3.122 Odc1
ornithine decarboxylase, structural 1
chr11_+_103635438 3.119 NM_009521
Wnt3
wingless-related MMTV integration site 3
chr2_+_115407409 3.118 NM_001145898
NM_207264
BC052040

cDNA sequence BC052040

chr13_-_12742377 3.117 Gpr137b-ps
Gpr137b
G protein-coupled receptor 137B, pseudogene
G protein-coupled receptor 137B

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
1.75 1.04e-16 GO:0044260 cellular macromolecule metabolic process
1.55 2.86e-14 GO:0044237 cellular metabolic process
2.01 2.12e-13 GO:0010467 gene expression
1.81 4.50e-13 GO:0034641 cellular nitrogen compound metabolic process
1.79 5.51e-13 GO:0006807 nitrogen compound metabolic process
1.61 8.80e-13 GO:0043170 macromolecule metabolic process
1.51 1.08e-12 GO:0044238 primary metabolic process
1.85 1.26e-12 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.92 5.57e-12 GO:0090304 nucleic acid metabolic process
1.95 1.52e-10 GO:0016070 RNA metabolic process
1.42 1.74e-10 GO:0008152 metabolic process
1.75 4.07e-09 GO:0044249 cellular biosynthetic process
1.72 9.45e-09 GO:0009058 biosynthetic process
1.86 1.00e-08 GO:0034645 cellular macromolecule biosynthetic process
1.84 1.75e-08 GO:0009059 macromolecule biosynthetic process
1.79 2.15e-06 GO:0044267 cellular protein metabolic process
1.68 4.20e-06 GO:0010468 regulation of gene expression
1.64 4.98e-06 GO:0071840 cellular component organization or biogenesis
1.75 7.56e-06 GO:0071841 cellular component organization or biogenesis at cellular level
3.24 2.61e-05 GO:0016568 chromatin modification
3.01 4.96e-05 GO:0006325 chromatin organization
1.65 5.42e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
3.37 6.01e-05 GO:0006412 translation
1.63 1.12e-04 GO:0010556 regulation of macromolecule biosynthetic process
2.59 3.35e-04 GO:0051276 chromosome organization
1.58 3.70e-04 GO:0031326 regulation of cellular biosynthetic process
1.57 4.07e-04 GO:0009889 regulation of biosynthetic process
1.50 4.44e-04 GO:0060255 regulation of macromolecule metabolic process
1.63 4.87e-04 GO:0051252 regulation of RNA metabolic process
2.51 4.93e-04 GO:0006396 RNA processing
1.85 5.20e-04 GO:0006996 organelle organization
3.75 6.56e-04 GO:0022613 ribonucleoprotein complex biogenesis
1.74 7.31e-04 GO:0006351 transcription, DNA-dependent
1.74 7.87e-04 GO:0032774 RNA biosynthetic process
1.54 9.06e-04 GO:0016043 cellular component organization
3.63 1.10e-03 GO:0016569 covalent chromatin modification
1.61 1.14e-03 GO:0006355 regulation of transcription, DNA-dependent
1.56 1.28e-03 GO:0019538 protein metabolic process
3.55 1.53e-03 GO:0071843 cellular component biogenesis at cellular level
1.46 1.76e-03 GO:0031323 regulation of cellular metabolic process
1.62 2.59e-03 GO:0071842 cellular component organization at cellular level
1.45 3.19e-03 GO:0080090 regulation of primary metabolic process
3.50 3.54e-03 GO:0016570 histone modification
1.16 4.69e-03 GO:0009987 cellular process
4.04 7.15e-03 GO:0042254 ribosome biogenesis
1.51 7.29e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.96 9.32e-03 GO:0032446 protein modification by small protein conjugation
1.49 1.18e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.44 1.29e-02 GO:0032502 developmental process
1.38 1.63e-02 GO:0019222 regulation of metabolic process
3.04 1.70e-02 GO:0034660 ncRNA metabolic process
2.70 1.79e-02 GO:0070647 protein modification by small protein conjugation or removal
1.98 2.10e-02 GO:0007049 cell cycle
1.63 2.12e-02 GO:0043412 macromolecule modification
3.24 3.37e-02 GO:0034470 ncRNA processing
34.47 3.76e-02 GO:0006344 maintenance of chromatin silencing

Gene overrepresentation in compartment category:

enrichment p-value GO term description
1.83 1.40e-23 GO:0005634 nucleus
1.38 5.81e-19 GO:0044424 intracellular part
1.36 2.64e-18 GO:0005622 intracellular
1.43 7.13e-18 GO:0043229 intracellular organelle
1.43 1.26e-17 GO:0043226 organelle
1.46 7.09e-17 GO:0043231 intracellular membrane-bounded organelle
1.46 1.02e-16 GO:0043227 membrane-bounded organelle
2.34 7.64e-16 GO:0044428 nuclear part
2.37 5.79e-13 GO:0031981 nuclear lumen
2.18 7.82e-12 GO:0031974 membrane-enclosed lumen
1.66 1.98e-11 GO:0044446 intracellular organelle part
2.16 3.14e-11 GO:0070013 intracellular organelle lumen
2.16 3.53e-11 GO:0043233 organelle lumen
1.63 1.26e-10 GO:0044422 organelle part
2.29 1.56e-07 GO:0005654 nucleoplasm
1.74 3.59e-07 GO:0043228 non-membrane-bounded organelle
1.74 3.59e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.60 4.37e-07 GO:0032991 macromolecular complex
3.20 6.78e-07 GO:0005730 nucleolus
1.29 5.24e-06 GO:0005737 cytoplasm
2.33 5.06e-05 GO:0044451 nucleoplasm part
2.54 1.94e-04 GO:0030529 ribonucleoprotein complex
1.53 3.56e-04 GO:0043234 protein complex
1.71 1.84e-03 GO:0005829 cytosol
1.10 6.29e-03 GO:0005623 cell
1.10 6.29e-03 GO:0044464 cell part
2.97 2.89e-02 GO:0005635 nuclear envelope

Gene overrepresentation in function category:

enrichment p-value GO term description
1.86 1.68e-10 GO:0003676 nucleic acid binding
2.86 3.16e-10 GO:0003723 RNA binding
1.21 5.19e-05 GO:0005488 binding
5.19 1.52e-04 GO:0008135 translation factor activity, nucleic acid binding
2.70 2.03e-04 GO:0016874 ligase activity
3.17 3.86e-04 GO:0016879 ligase activity, forming carbon-nitrogen bonds
3.50 4.18e-04 GO:0019787 small conjugating protein ligase activity
1.62 4.73e-04 GO:0000166 nucleotide binding
3.25 7.72e-04 GO:0016881 acid-amino acid ligase activity
3.23 2.54e-03 GO:0003682 chromatin binding
3.20 8.35e-03 GO:0004842 ubiquitin-protein ligase activity
2.57 1.26e-02 GO:0008134 transcription factor binding
1.55 2.94e-02 GO:0003677 DNA binding
1.26 3.35e-02 GO:0005515 protein binding
7.39 4.20e-02 GO:0003746 translation elongation factor activity