Motif ID: ATF4.p2

Z-value: 1.699

Transcription factors associated with ATF4.p2:

NameEntrezDescription
Atf4 11911 activating transcription factor 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Atf4chr15_+_800859230.382.2e-02Click!


Activity profile for motif ATF4.p2.

activity profile for motif ATF4.p2


Sorted Z-values histogram for motif ATF4.p2

Sorted Z-values for motif ATF4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr3_+_134875526 10.319 NM_173762
Cenpe
centromere protein E
chr2_-_56967331 9.834 NM_013613
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr1_-_71699671 9.371 NM_010233
Fn1
fibronectin 1
chr10_-_115024814 9.003 NM_010195
Lgr5
leucine rich repeat containing G protein coupled receptor 5
chr7_+_104936996 8.999 Pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr2_+_109120894 8.112 NM_139303
Kif18a
kinesin family member 18A
chr11_-_86621074 8.050 Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr18_+_11815869 7.755 Rbbp8
retinoblastoma binding protein 8
chr3_-_127256215 7.381 NM_138593
Larp7
La ribonucleoprotein domain family, member 7
chr14_-_69902984 7.242 Slc25a37
solute carrier family 25, member 37
chr7_+_52973440 7.185 NM_009077
Rpl18
ribosomal protein L18
chr9_+_113650560 6.563 NM_001114347
Clasp2
CLIP associating protein 2
chr4_-_131631150 6.452 Epb4.1
erythrocyte protein band 4.1
chr11_-_77978936 6.321 NM_009423
Traf4
TNF receptor associated factor 4
chr4_-_133801438 6.314 NM_024215
Zfp593
zinc finger protein 593
chr3_+_137806411 6.184 NM_175389
Rg9mtd2
RNA (guanine-9-) methyltransferase domain containing 2
chrX_-_58146562 6.138 NM_009237
Sox3
SRY-box containing gene 3
chr13_+_23622912 6.041 NM_153173
Hist1h4h
histone cluster 1, H4h
chr3_-_19211000 5.805 NM_001122759
Pde7a
phosphodiesterase 7A
chr11_+_101526871 5.756 Arl4d
ADP-ribosylation factor-like 4D
chr10_-_92185071 5.678 NM_008682
Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr2_-_3392226 5.523 NM_022724
Suv39h2
suppressor of variegation 3-9 homolog 2 (Drosophila)
chr16_+_38562924 5.486 NM_026407
Tmem39a
transmembrane protein 39a
chr4_-_117169519 5.476 NM_025739
Rnf220
ring finger protein 220
chr13_-_23853025 5.377 NM_178192
Hist1h4a
histone cluster 1, H4a
chr17_-_57150821 5.315 Gtf2f1
general transcription factor IIF, polypeptide 1
chr13_-_53568111 5.107 NM_013601
Msx2
homeobox, msh-like 2
chr9_-_119231439 5.052 Oxsr1
oxidative-stress responsive 1
chr3_+_30993952 4.945 NM_001039090
NM_011386
Skil

SKI-like

chr7_+_119822831 4.843 NM_001166584
NM_009346
Tead1

TEA domain family member 1

chr4_+_56815193 4.818 NM_001081420
BC026590
cDNA sequence BC026590
chr14_-_47896464 4.799 Wdhd1
WD repeat and HMG-box DNA binding protein 1
chr5_-_111082387 4.789 NM_153570
Noc4l
nucleolar complex associated 4 homolog (S. cerevisiae)
chr8_-_41597015 4.783 Cnot7
CCR4-NOT transcription complex, subunit 7
chr15_+_89186142 4.741 NM_001115132
NM_025795
Ncaph2

non-SMC condensin II complex, subunit H2

chr9_+_74709673 4.699 NM_008262
Onecut1
one cut domain, family member 1
chr3_-_127256181 4.661 Larp7
La ribonucleoprotein domain family, member 7
chr5_-_111082269 4.595 Noc4l
nucleolar complex associated 4 homolog (S. cerevisiae)
chr14_-_47896506 4.589 Wdhd1
WD repeat and HMG-box DNA binding protein 1
chr17_+_15841889 4.575 NM_007690
Chd1
chromodomain helicase DNA binding protein 1
chr17_+_35118956 4.380 NM_030597
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr12_-_28027541 4.353 NM_009234
Sox11
SRY-box containing gene 11
chr14_+_47896669 4.337 NM_080843
Socs4
suppressor of cytokine signaling 4
chr2_+_156665812 4.323 NM_173396
Tgif2
TGFB-induced factor homeobox 2
chr19_-_4625574 4.248 NM_023131
Rce1
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
chr11_+_22890632 4.240 Cct4
chaperonin containing Tcp1, subunit 4 (delta)
chr5_+_111082466 4.220 NM_027156
Ddx51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr7_-_26035683 4.214 NM_010155
Erf
Ets2 repressor factor
chr3_-_36470904 4.213 NM_009828
Ccna2
cyclin A2
chr3_+_127256406 4.117 NM_197997
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr9_-_20781133 4.031 S1pr2
sphingosine-1-phosphate receptor 2
chr16_-_33967064 3.960 NM_009471
Umps
uridine monophosphate synthetase
chr17_+_56179740 3.917 NM_013733
Chaf1a
chromatin assembly factor 1, subunit A (p150)
chr11_+_60351469 3.906 Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr13_-_112280018 3.905 NM_001122963
NM_028487
Gpbp1

GC-rich promoter binding protein 1

chr17_+_75404865 3.900 NM_019919
Ltbp1
latent transforming growth factor beta binding protein 1
chr11_+_22890575 3.899 NM_009837
Cct4
chaperonin containing Tcp1, subunit 4 (delta)
chr13_+_58258986 3.894 NM_001048060
NM_198004
5133401N09Rik

RIKEN cDNA 5133401N09 gene

chr13_+_22135065 3.876 NM_178198
Hist1h2bj
histone cluster 1, H2bj
chr4_+_140857147 3.860 NM_010139
Epha2
Eph receptor A2
chr10_+_43988192 3.857 Atg5
autophagy-related 5 (yeast)
chr3_-_36470882 3.851 Ccna2
cyclin A2
chr2_-_132078887 3.808 NM_011045
Pcna
proliferating cell nuclear antigen
chr7_-_150085870 3.761 NM_009377
Th
tyrosine hydroxylase
chr12_+_8214912 3.756 NM_172401
NM_001167768
NM_001167767
1110057K04Rik


RIKEN cDNA 1110057K04 gene


chr17_-_71876127 3.754 Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr6_-_127100954 3.739 NM_009829
Ccnd2
cyclin D2
chr17_-_28046158 3.733 Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_-_126959605 3.704 NM_144818
Ncaph
non-SMC condensin I complex, subunit H
chr17_-_74694322 3.689 Memo1
mediator of cell motility 1
chr9_+_55388955 3.685 NM_027397
Isl2
insulin related protein 2 (islet 2)
chr4_-_123427465 3.680 NM_023423
Akirin1
akirin 1
chr17_-_71876150 3.677 NM_023294
Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr5_+_151325197 3.674 NM_009765
NM_001081001
Brca2

breast cancer 2

chr14_+_64479167 3.667 Pinx1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr17_+_29169612 3.662 Srsf3
serine/arginine-rich splicing factor 3
chr11_-_86621130 3.644 NM_026191
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr11_-_97490978 3.639 NM_175332
E130012A19Rik
RIKEN cDNA E130012A19 gene
chr8_+_77633426 3.637 NM_008566
Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr17_+_75404893 3.610 Ltbp1
latent transforming growth factor beta binding protein 1
chr9_+_108462759 3.584 NM_011830
Impdh2
inosine 5'-phosphate dehydrogenase 2
chr5_+_143722032 3.566 NM_007984
Fscn1
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
chr12_+_34642516 3.552 NM_011658
Twist1
twist homolog 1 (Drosophila)
chr5_-_4104331 3.532 Cyp51
cytochrome P450, family 51
chr11_-_74537524 3.487 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr15_+_34167908 3.450 Laptm4b
lysosomal-associated protein transmembrane 4B
chr6_-_49214015 3.428 NM_198102
Tra2a
transformer 2 alpha homolog (Drosophila)
chr11_+_43342241 3.426 NM_001045530
Ccnjl
cyclin J-like
chr4_-_116806403 3.419 NM_013807
Plk3
polo-like kinase 3 (Drosophila)
chr13_-_64376186 3.418 NM_172587
Cdc14b
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr8_-_72149070 3.409 NM_001045553
Zfp868
zinc finger protein 868
chr14_-_67691221 3.390 NM_028032
Ppp2r2a
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform
chr17_-_37095372 3.359 NM_023162
Znrd1
zinc ribbon domain containing, 1
chr17_-_26645403 3.339 NM_013642
Dusp1
dual specificity phosphatase 1
chr2_+_14976877 3.311 NM_029466
Arl5b
ADP-ribosylation factor-like 5B
chr10_+_79611013 3.278 NM_021565
Midn
midnolin
chr13_-_108680257 3.270 NM_145456
Zswim6
zinc finger, SWIM domain containing 6
chr4_-_81088575 3.270 NM_010820
Mpdz
multiple PDZ domain protein
chr11_+_22890640 3.268 Cct4
chaperonin containing Tcp1, subunit 4 (delta)
chr15_+_93228780 3.264 NM_001083114
NM_146062
NM_175363
Pphln1


periphilin 1


chr4_-_122638401 3.222 NM_029662
Mfsd2a
major facilitator superfamily domain containing 2A
chr16_+_24393435 3.193 NM_178665
Lpp
LIM domain containing preferred translocation partner in lipoma
chr2_+_35992148 3.182 Mrrf
mitochondrial ribosome recycling factor
chrX_-_53851046 3.174 NM_146234
Mmgt1
membrane magnesium transporter 1
chr11_-_76057153 3.146 Glod4
glyoxalase domain containing 4
chr8_+_74659107 3.119 NM_001001491
Tpm4
tropomyosin 4
chr5_-_137971968 3.101 Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr7_-_52973262 3.082 NM_001172561
NM_203280
Sphk2

sphingosine kinase 2

chr2_-_127614580 3.052 NM_016902
Nphp1
nephronophthisis 1 (juvenile) homolog (human)
chr17_+_32173346 3.050


chr3_+_40603872 3.010 NM_011495
Plk4
polo-like kinase 4 (Drosophila)
chr9_+_122860175 2.965 NM_010620
Kif15
kinesin family member 15
chr2_+_132079092 2.849


chr11_-_113613040 2.824 NM_001163346
Cdc42ep4
CDC42 effector protein (Rho GTPase binding) 4
chr12_+_33505307 2.821 Nampt
nicotinamide phosphoribosyltransferase
chr19_+_59335367 2.792 NM_172523
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr7_+_51723361 2.791 NM_025368
Josd2
Josephin domain containing 2
chr4_-_131631226 2.789 NM_001128607
Epb4.1
erythrocyte protein band 4.1
chr4_-_55545337 2.780 NM_010637
Klf4
Kruppel-like factor 4 (gut)
chr5_-_4104696 2.773 NM_020010
Cyp51
cytochrome P450, family 51
chr14_+_64479129 2.771 NM_028228
Pinx1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr8_-_4325051 2.765 NM_010485
Elavl1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
chr13_+_22036962 2.763 NM_183014
Zfp184
zinc finger protein 184 (Kruppel-like)
chr11_-_102046532 2.746 NM_172947
Lsm12
LSM12 homolog (S. cerevisiae)
chr16_-_92400226 2.688 NM_019466
Rcan1
regulator of calcineurin 1
chr5_+_112772106 2.684 NM_138646
Hps4
Hermansky-Pudlak syndrome 4 homolog (human)
chr11_+_117710532 2.682 NM_001012273
NM_009689
Birc5

baculoviral IAP repeat-containing 5

chr11_+_69137459 2.667 NM_001024206
Trappc1
trafficking protein particle complex 1
chr7_+_51723446 2.667 Josd2
Josephin domain containing 2
chr14_-_21208006 2.666 NM_134081
Dnajc9
DnaJ (Hsp40) homolog, subfamily C, member 9
chr11_-_72028494 2.661 Med31
mediator of RNA polymerase II transcription, subunit 31 homolog (yeast)
chr9_-_96378951 2.620 NM_011279
Rnf7
ring finger protein 7
chr16_-_17928207 2.617 Slc25a1
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chr7_+_51751957 2.616 NM_028169
Fam71e1
family with sequence similarity 71, member E1
chr10_+_126817878 2.611


chr3_-_36470845 2.602 Ccna2
cyclin A2
chr13_+_8885147 2.599 Idi1
isopentenyl-diphosphate delta isomerase
chr17_-_95149352 2.590 Mettl4
methyltransferase like 4
chr12_+_103981919 2.583 NM_177140
D230037D09Rik
RIKEN cDNA D230037D09 gene
chr8_-_124999921 2.572 NM_001033142
Rnf166
ring finger protein 166
chrX_+_147955201 2.571 NM_001113354
NM_177201
Phf8

PHD finger protein 8

chr2_-_179777080 2.570 NM_011969
Psma7
proteasome (prosome, macropain) subunit, alpha type 7
chr14_+_76245115 2.566 Tpt1
tumor protein, translationally-controlled 1
chr4_-_125879832 2.552 NM_146153
Thrap3
thyroid hormone receptor associated protein 3
chr17_+_47027617 2.546 Tbcc
tubulin-specific chaperone C
chr13_-_107727010 2.542 Ipo11
importin 11
chr8_-_126473145 2.527 NM_172288
Nup133
nucleoporin 133
chr1_-_193399352 2.518 Dtl
denticleless homolog (Drosophila)
chr7_+_30768973 2.518 NM_001033355
NM_001167872
NM_001167873
Zfp568


zinc finger protein 568


chr4_-_115726385 2.509 Nsun4
NOL1/NOP2/Sun domain family, member 4
chr6_+_64992810 2.496 Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr6_+_64992861 2.466 Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr3_-_95799554 2.461 NM_023320
Plekho1
pleckstrin homology domain containing, family O member 1
chr9_-_57612906 2.460 Clk3
CDC-like kinase 3
chr3_+_122122640 2.459 NM_013867
Bcar3
breast cancer anti-estrogen resistance 3
chr9_+_69245718 2.433 NM_145618
Narg2
NMDA receptor-regulated gene 2
chr14_+_67254087 2.421 NM_013461
Adra1a
adrenergic receptor, alpha 1a
chr1_+_133807034 2.405 NM_001145804
NM_175294
Nucks1

nuclear casein kinase and cyclin-dependent kinase substrate 1

chr4_+_136025675 2.400 NM_024452
Luzp1
leucine zipper protein 1
chr19_-_4615661 2.391 NM_153388
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr5_+_112772131 2.385 Hps4
Hermansky-Pudlak syndrome 4 homolog (human)
chr10_+_85334563 2.371 NM_133993
Pwp1
PWP1 homolog (S. cerevisiae)
chr16_-_4077714 2.338 NM_026508
Trap1
TNF receptor-associated protein 1
chr6_+_58590475 2.338 Abcg2
ATP-binding cassette, sub-family G (WHITE), member 2
chr9_+_44412931 2.336 NM_001110826
NM_007841
NM_181324
Ddx6


DEAD (Asp-Glu-Ala-Asp) box polypeptide 6


chr19_-_25036047 2.330 NM_146097
Cbwd1
COBW domain containing 1
chr10_+_57909577 2.326 NM_011240
Ranbp2
RAN binding protein 2
chr19_+_37000568 2.299 NM_001080706
Btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, (Mot1 homolog, S. cerevisiae)
chr17_-_53828596 2.288 NM_028232
Sgol1
shugoshin-like 1 (S. pombe)
chr10_+_57909613 2.286 Ranbp2
RAN binding protein 2
chr3_+_157699644 2.280 NM_024194
Lrrc40
leucine rich repeat containing 40
chr14_+_76245136 2.277 Tpt1
tumor protein, translationally-controlled 1
chr18_+_60934249 2.263 NM_020600
Rps14
ribosomal protein S14
chr10_+_57960671 2.261 NM_001162956
Ccdc138
coiled-coil domain containing 138
chr18_-_24688688 2.255 NM_144861
Rprd1a
regulation of nuclear pre-mRNA domain containing 1A
chr17_-_95149280 2.255 Mettl4
methyltransferase like 4
chr14_+_8912873 2.254 Rpp14
ribonuclease P 14 subunit (human)
chr8_-_88079180 2.250 Dnaja2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr1_+_63777187 2.250 NM_172422
Fastkd2
FAST kinase domains 2
chr17_+_35118792 2.247 NM_001110101
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr15_-_90880241 2.236 NM_001109040
NM_001109041
NM_001109042
NM_016705
Kif21a



kinesin family member 21A



chr9_+_21351307 2.234 NM_021531
NM_153141
Carm1

coactivator-associated arginine methyltransferase 1

chr8_+_119445639 2.223 NM_028131
Cenpn
centromere protein N
chr6_-_82724366 2.216 NM_013820
Hk2
hexokinase 2
chr5_+_130231003 2.205 Gbas
glioblastoma amplified sequence
chr12_+_110031153 2.203 Yy1
YY1 transcription factor
chr14_+_79987495 2.189 NM_026474
Sugt1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr17_-_37095420 2.180 Znrd1
zinc ribbon domain containing, 1
chr14_-_19103447 2.179 NM_025586
Rpl15
ribosomal protein L15
chr5_+_73305509 2.173 NM_001113423
NM_153567
Slain2

SLAIN motif family, member 2

chr12_+_33505175 2.148 NM_021524
Nampt
nicotinamide phosphoribosyltransferase
chr4_+_115410325 2.140 4732418C07Rik
RIKEN cDNA 4732418C07 gene
chr7_+_117205194 2.131 NM_009281
Zfp143
zinc finger protein 143
chr18_+_80403500 2.121 NM_001038608
NM_025299
Txnl4a

thioredoxin-like 4A

chr16_-_96349292 2.121 NM_008251
Hmgn1
high mobility group nucleosomal binding domain 1
chr19_-_40662819 2.113 NM_019698
NM_153554
Aldh18a1

aldehyde dehydrogenase 18 family, member A1

chr2_+_30093236 2.110 NM_177725
Lrrc8a
leucine rich repeat containing 8A
chr14_-_47896531 2.102 NM_172598
Wdhd1
WD repeat and HMG-box DNA binding protein 1
chr1_-_168339909 2.079 NM_001142948
NM_175170
Pogk

pogo transposable element with KRAB domain

chr17_-_31992708 2.078 NM_010831
Sik1
salt inducible kinase 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
1.92 4.38e-17 GO:0044260 cellular macromolecule metabolic process
1.67 2.17e-14 GO:0044237 cellular metabolic process
1.64 1.09e-13 GO:0044238 primary metabolic process
1.76 1.61e-13 GO:0043170 macromolecule metabolic process
2.03 1.25e-12 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.12 7.17e-12 GO:0090304 nucleic acid metabolic process
1.90 6.65e-11 GO:0034641 cellular nitrogen compound metabolic process
1.88 8.65e-11 GO:0006807 nitrogen compound metabolic process
2.09 2.13e-10 GO:0010467 gene expression
2.09 3.57e-09 GO:0016070 RNA metabolic process
1.48 3.61e-09 GO:0008152 metabolic process
3.41 3.47e-07 GO:0006396 RNA processing
2.78 1.74e-06 GO:0007049 cell cycle
3.58 2.13e-06 GO:0022403 cell cycle phase
3.73 3.09e-06 GO:0000278 mitotic cell cycle
5.72 3.31e-06 GO:0000226 microtubule cytoskeleton organization
4.65 7.07e-06 GO:0000087 M phase of mitotic cell cycle
3.04 1.20e-05 GO:0022402 cell cycle process
1.90 1.35e-05 GO:0044267 cellular protein metabolic process
29.72 1.52e-05 GO:0051313 attachment of spindle microtubules to chromosome
1.68 1.74e-05 GO:0060255 regulation of macromolecule metabolic process
3.73 2.23e-05 GO:0000279 M phase
4.52 2.55e-05 GO:0000280 nuclear division
4.52 2.55e-05 GO:0007067 mitosis
1.23 2.97e-05 GO:0009987 cellular process
1.64 4.40e-05 GO:0031323 regulation of cellular metabolic process
1.86 4.55e-05 GO:0071841 cellular component organization or biogenesis at cellular level
4.35 5.01e-05 GO:0048285 organelle fission
1.82 5.22e-05 GO:0034645 cellular macromolecule biosynthetic process
1.80 7.53e-05 GO:0009059 macromolecule biosynthetic process
4.24 7.71e-05 GO:0007017 microtubule-based process
1.56 1.31e-04 GO:0019222 regulation of metabolic process
1.60 2.09e-04 GO:0080090 regulation of primary metabolic process
1.75 2.16e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.78 2.29e-04 GO:0051252 regulation of RNA metabolic process
15.07 2.86e-04 GO:0034453 microtubule anchoring
1.73 3.14e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.71 3.17e-04 GO:0010468 regulation of gene expression
1.77 4.21e-04 GO:0006355 regulation of transcription, DNA-dependent
1.81 4.79e-04 GO:0071842 cellular component organization at cellular level
1.68 6.81e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
10.43 8.80e-04 GO:0031023 microtubule organizing center organization
1.62 9.13e-04 GO:0044249 cellular biosynthetic process
1.67 1.06e-03 GO:0051171 regulation of nitrogen compound metabolic process
16.51 1.17e-03 GO:0050000 chromosome localization
16.51 1.17e-03 GO:0051303 establishment of chromosome localization
1.99 1.21e-03 GO:0006996 organelle organization
2.03 1.73e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.59 1.84e-03 GO:0009058 biosynthetic process
1.61 2.40e-03 GO:0071840 cellular component organization or biogenesis
3.54 2.55e-03 GO:0008380 RNA splicing
1.84 3.14e-03 GO:0006351 transcription, DNA-dependent
1.83 3.33e-03 GO:0032774 RNA biosynthetic process
3.17 4.28e-03 GO:0051301 cell division
1.61 5.35e-03 GO:0009889 regulation of biosynthetic process
1.61 5.99e-03 GO:0031326 regulation of cellular biosynthetic process
5.24 9.74e-03 GO:0007059 chromosome segregation
16.51 9.91e-03 GO:0051310 metaphase plate congression
24.76 1.28e-02 GO:0008608 attachment of spindle microtubules to kinetochore
1.91 1.41e-02 GO:0031325 positive regulation of cellular metabolic process
6.28 1.49e-02 GO:0051651 maintenance of location in cell
1.87 1.67e-02 GO:0009893 positive regulation of metabolic process
1.59 1.67e-02 GO:0019538 protein metabolic process
4.91 1.82e-02 GO:0051640 organelle localization
2.06 2.05e-02 GO:0044085 cellular component biogenesis
1.55 2.60e-02 GO:0016043 cellular component organization
3.77 2.77e-02 GO:0022613 ribonucleoprotein complex biogenesis
2.65 2.81e-02 GO:0007010 cytoskeleton organization
3.58 4.98e-02 GO:0071843 cellular component biogenesis at cellular level

Gene overrepresentation in compartment category:

enrichment p-value GO term description
2.17 2.22e-31 GO:0005634 nucleus
1.50 5.58e-25 GO:0005622 intracellular
1.50 6.68e-24 GO:0044424 intracellular part
1.65 2.01e-23 GO:0043227 membrane-bounded organelle
1.65 4.08e-23 GO:0043231 intracellular membrane-bounded organelle
1.58 4.11e-23 GO:0043226 organelle
1.58 7.03e-23 GO:0043229 intracellular organelle
2.46 1.42e-12 GO:0044428 nuclear part
1.69 2.62e-08 GO:0044446 intracellular organelle part
2.33 2.86e-08 GO:0031981 nuclear lumen
1.67 4.85e-08 GO:0044422 organelle part
2.13 2.60e-07 GO:0031974 membrane-enclosed lumen
1.74 3.58e-07 GO:0032991 macromolecular complex
2.11 6.17e-07 GO:0070013 intracellular organelle lumen
2.11 6.67e-07 GO:0043233 organelle lumen
1.34 9.77e-06 GO:0005737 cytoplasm
1.15 1.86e-05 GO:0005623 cell
1.15 1.86e-05 GO:0044464 cell part
2.31 3.51e-05 GO:0005654 nucleoplasm
1.77 3.79e-05 GO:0043228 non-membrane-bounded organelle
1.77 3.79e-05 GO:0043232 intracellular non-membrane-bounded organelle
3.02 2.28e-04 GO:0044427 chromosomal part
2.79 9.46e-04 GO:0005694 chromosome
1.60 1.46e-03 GO:0043234 protein complex
2.51 1.89e-03 GO:0015630 microtubule cytoskeleton
4.40 4.21e-03 GO:0000775 chromosome, centromeric region
7.88 5.73e-03 GO:0005643 nuclear pore
3.47 1.28e-02 GO:0005813 centrosome
5.18 1.30e-02 GO:0000776 kinetochore
10.77 1.79e-02 GO:0030532 small nuclear ribonucleoprotein complex
1.72 3.01e-02 GO:0005829 cytosol
24.76 3.45e-02 GO:0005682 U5 snRNP
3.14 3.71e-02 GO:0005815 microtubule organizing center
5.88 3.94e-02 GO:0046930 pore complex
2.36 4.22e-02 GO:0030529 ribonucleoprotein complex

Gene overrepresentation in function category:

enrichment p-value GO term description
1.97 5.07e-09 GO:0003676 nucleic acid binding
2.01 1.02e-07 GO:0000166 nucleotide binding
1.28 1.14e-06 GO:0005488 binding
2.20 1.27e-06 GO:0005524 ATP binding
2.16 2.48e-06 GO:0032559 adenyl ribonucleotide binding
2.15 2.98e-06 GO:0030554 adenyl nucleotide binding
2.74 5.15e-06 GO:0003723 RNA binding
1.95 2.61e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.91 5.46e-05 GO:0032555 purine ribonucleotide binding
1.91 5.57e-05 GO:0032553 ribonucleotide binding
1.91 6.33e-05 GO:0017076 purine nucleotide binding
1.81 8.02e-04 GO:0003677 DNA binding
10.32 2.52e-02 GO:0035064 methylated histone residue binding
1.31 2.53e-02 GO:0005515 protein binding
5.08 4.36e-02 GO:0008026 ATP-dependent helicase activity
5.08 4.36e-02 GO:0070035 purine NTP-dependent helicase activity