Motif ID: CEBPA,B_DDIT3.p2

Z-value: 0.582

Transcription factors associated with CEBPA,B_DDIT3.p2:

NameEntrezDescription
Cebpa 12606 CCAAT/enhancer binding protein (C/EBP), alpha
Cebpb 12608 CCAAT/enhancer binding protein (C/EBP), beta
Ddit3 13198 DNA-damage inducible transcript 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Cebpbchr2_+_167514489-0.307.6e-02Click!
Cebpachr7_+_35904310-0.271.1e-01Click!
Ddit3chr10_+_1267278460.153.8e-01Click!


Activity profile for motif CEBPA,B_DDIT3.p2.

activity profile for motif CEBPA,B_DDIT3.p2


Sorted Z-values histogram for motif CEBPA,B_DDIT3.p2

Sorted Z-values for motif CEBPA,B_DDIT3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CEBPA,B_DDIT3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr16_+_22892112 7.283 NM_013465
Ahsg
alpha-2-HS-glycoprotein
chr7_+_152082435 6.591 NM_008003
Fgf15
fibroblast growth factor 15
chr3_+_66023884 2.666 Ptx3
pentraxin related gene
chr4_+_63005581 2.635 NM_008768
Orm1
orosomucoid 1
chr3_+_66023808 2.170 NM_008987
Ptx3
pentraxin related gene
chr15_-_96529998 2.113 NM_175121
Slc38a2
solute carrier family 38, member 2
chr12_+_53800369 1.984 NM_198111
Akap6
A kinase (PRKA) anchor protein 6
chr3_+_146260100 1.916 NM_009474
Uox
urate oxidase
chr7_+_74792295 1.846 NM_001168475
NM_001168476
NM_001168477
NM_025905
Ttc23



tetratricopeptide repeat domain 23



chr11_+_108256590 1.774 NM_013475
Apoh
apolipoprotein H
chr3_-_96067233 1.038 NM_033596
Hist2h4
histone cluster 2, H4
chr19_-_8893759 0.994 NM_027412
Ttc9c
tetratricopeptide repeat domain 9C
chr8_+_83017933 0.975 NM_010369
Gypa
glycophorin A
chr2_+_145685882 0.960 Rin2
Ras and Rab interactor 2
chr16_+_22892156 0.927 Ahsg
alpha-2-HS-glycoprotein
chr11_-_102091406 0.863 NM_001077696
NM_010412
Hdac5

histone deacetylase 5

chr16_+_22892125 0.742 Ahsg
alpha-2-HS-glycoprotein
chr4_+_55362949 0.742 Rad23b
RAD23b homolog (S. cerevisiae)
chr11_+_57822347 0.714 NM_028451
Larp1
La ribonucleoprotein domain family, member 1
chr4_+_43970559 0.675 NM_027450
Glipr2
GLI pathogenesis-related 2
chr9_+_66198310 0.660 Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr3_+_101814059 0.655 NM_178777
Nhlh2
nescient helix loop helix 2
chr5_+_93522440 0.611 NM_001009818
Sept11
septin 11
chr5_-_5265981 0.573 Cdk14
cyclin-dependent kinase 14
chr12_-_82068951 0.569 Slc10a1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr7_-_26506741 0.568


chr10_-_67741461 0.519 NM_023598
Arid5b
AT rich interactive domain 5B (MRF1-like)
chr2_-_84567398 0.479 Clp1
CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae)
chr11_-_120504978 0.462 NM_144795
Pycr1
pyrroline-5-carboxylate reductase 1
chr9_+_107982741 0.460 NM_008243
Mst1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr1_+_82313139 0.452 NM_029777
Rhbdd1
rhomboid domain containing 1
chr11_+_3931731 0.447 NM_146013
Sec14l4
SEC14-like 4 (S. cerevisiae)
chr7_-_140179678 0.396 Ctbp2
C-terminal binding protein 2
chr13_-_108516475 0.391 Zswim6
zinc finger, SWIM domain containing 6
chr10_-_36855292 0.374 Marcks
myristoylated alanine rich protein kinase C substrate
chr6_-_82724366 0.366 NM_013820
Hk2
hexokinase 2
chr11_-_79775842 0.360 NM_144826
Utp6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr13_+_42776161 0.355 Phactr1
phosphatase and actin regulator 1
chr5_-_37087209 0.353 D5Ertd579e
DNA segment, Chr 5, ERATO Doi 579, expressed
chr3_+_123149830 0.351 NM_008939
Prss12
protease, serine, 12 neurotrypsin (motopsin)
chr7_-_128217980 0.331 NM_030691
Igsf6
immunoglobulin superfamily, member 6
chrM_+_11812 0.323


chr6_-_145024487 0.322 Bcat1
branched chain aminotransferase 1, cytosolic
chr11_+_93905557 0.312 Spag9
sperm associated antigen 9
chr11_+_93905443 0.309 Spag9
sperm associated antigen 9
chr5_-_104406406 0.306 NM_001163486
NM_198030
Hsd17b13

hydroxysteroid (17-beta) dehydrogenase 13

chrX_-_7651846 0.297 NM_011514
Suv39h1
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr15_-_96529121 0.286 Slc38a2
solute carrier family 38, member 2
chr11_-_55209320 0.283 Sparc
secreted acidic cysteine rich glycoprotein
chr1_-_9621172 0.275 2610203C22Rik
RIKEN cDNA 2610203C22 gene
chr6_+_90416405 0.270 Klf15
Kruppel-like factor 15
chrX_-_137908516 0.264 Col4a6
collagen, type IV, alpha 6
chr2_-_84567424 0.260 NM_133840
Clp1
CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae)
chr10_-_4707228 0.254 NM_011702
Vip
vasoactive intestinal polypeptide
chr19_+_45089665 0.247 NM_145503
NM_001130525
Lzts2

leucine zipper, putative tumor suppressor 2

chr3_+_103613439 0.235 NM_001163552
NM_001163553
NM_026193
Ap4b1


adaptor-related protein complex AP-4, beta 1


chr13_-_29044564 0.232 Sox4
SRY-box containing gene 4
chrX_+_106290703 0.231 NM_019989
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr7_+_26682681 0.230 NM_009999
Cyp2b10
cytochrome P450, family 2, subfamily b, polypeptide 10
chr10_-_121063321 0.221 NM_001081056
Xpot
exportin, tRNA (nuclear export receptor for tRNAs)
chr1_-_39634096 0.205 NM_001033135
Rnf149
ring finger protein 149
chr5_-_4104696 0.204 NM_020010
Cyp51
cytochrome P450, family 51
chr14_+_70945119 0.201 Reep4
receptor accessory protein 4
chr5_-_4104331 0.201 Cyp51
cytochrome P450, family 51
chr5_+_140918858 0.198 Eif3b
eukaryotic translation initiation factor 3, subunit B
chr16_+_33725541 0.197 Heg1
HEG homolog 1 (zebrafish)
chr1_+_59543450 0.195


chr7_+_26682646 0.194 Cyp2b10
cytochrome P450, family 2, subfamily b, polypeptide 10
chr11_+_120466611 0.188 Anapc11
anaphase promoting complex subunit 11
chr5_+_145901253 0.187 NM_001008705
Bud31
BUD31 homolog (yeast)
chr8_-_90483392 0.186 NM_033327
Zfp423
zinc finger protein 423
chr2_-_44972914 0.185 Zeb2
zinc finger E-box binding homeobox 2
chr14_+_76245115 0.183 Tpt1
tumor protein, translationally-controlled 1
chr19_+_30307417 0.175 Mbl2
mannose-binding lectin (protein C) 2
chr5_-_54098762 0.173 NM_009827
Cckar
cholecystokinin A receptor
chr8_-_55606109 0.172 Spcs3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr11_+_117623703 0.171 Tnrc6c
trinucleotide repeat containing 6C
chr1_+_91351373 0.167 NM_001037136
NM_178119
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chrM_+_8606 0.162 COX3
cytochrome c oxidase subunit III
chr8_+_113557991 0.161 Aars
alanyl-tRNA synthetase
chr8_+_107257897 0.159 NM_001190330
NM_133960
Ces2a

carboxylesterase 2A

chr2_+_172219293 0.156 NM_001033538
NM_001080820
Cass4

Cas scaffolding protein family member 4

chr16_+_22951144 0.153 NM_053176
Hrg
histidine-rich glycoprotein
chr2_-_32279522 0.149 Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr4_+_63023478 0.138 NM_011016
Orm2
orosomucoid 2
chr2_+_163519756 0.136 NM_011106
Pkig
protein kinase inhibitor, gamma
chr7_-_106387077 0.132 NM_177448
Mogat2
monoacylglycerol O-acyltransferase 2
chr6_-_145024451 0.132 Bcat1
branched chain aminotransferase 1, cytosolic
chr12_-_103056971 0.130 Fbln5
fibulin 5
chr1_+_89346303 0.130 Gigyf2
GRB10 interacting GYF protein 2
chr17_-_5440223 0.127 NM_027457
5730437N04Rik
RIKEN cDNA 5730437N04 gene
chr11_-_75236085 0.125 NM_011340
Serpinf1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr18_-_64676090 0.122 Nars
asparaginyl-tRNA synthetase
chr15_+_9265343 0.116 NM_144845
Ugt3a2
UDP glycosyltransferases 3 family, polypeptide A2
chr8_+_113557763 0.113 NM_146217
Aars
alanyl-tRNA synthetase
chr2_+_90585682 0.109 Fnbp4
formin binding protein 4
chr6_-_126485370 0.109 NM_145983
Kcna5
potassium voltage-gated channel, shaker-related subfamily, member 5
chr1_-_182160174 0.108 Psen2
presenilin 2
chr5_+_119214935 0.108 Med13l
mediator complex subunit 13-like
chr1_+_74421706 0.094 NM_013612
Slc11a1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chrX_+_132781054 0.094 Wbp5
WW domain binding protein 5
chr4_+_55362895 0.094 NM_009011
Rad23b
RAD23b homolog (S. cerevisiae)
chr1_+_176102903 0.093 NM_011465
Spna1
spectrin alpha 1
chr18_+_42713035 0.093 Tcerg1
transcription elongation regulator 1 (CA150)
chr6_+_88051917 0.084 Rpn1
ribophorin I
chr14_+_57506630 0.083 NM_029498
Zmym2
zinc finger, MYM-type 2
chrM_+_11027 0.082


chr17_+_35400983 0.078 H2-D1
histocompatibility 2, D region locus 1
chr7_-_52870858 0.078 NM_020013
Fgf21
fibroblast growth factor 21
chr11_-_6100453 0.077 NM_173748
Nudcd3
NudC domain containing 3
chr16_+_3838974 0.075 NM_008762
Olfr15
olfactory receptor 15
chr16_-_23029154 0.074 NM_001102409
NM_001102410
NM_201375
Kng2


kininogen 2


chr15_-_83207509 0.073


chr6_-_92484838 0.071 NM_001134459
Prickle2
prickle homolog 2 (Drosophila)
chr14_+_76245031 0.070 NM_009429
Tpt1
tumor protein, translationally-controlled 1
chr16_+_5086296 0.068


chr1_-_173210278 0.068 Ppox
protoporphyrinogen oxidase
chr3_-_89824973 0.065 Ubap2l
ubiquitin associated protein 2-like
chr5_-_44152043 0.062 Fbxl5
F-box and leucine-rich repeat protein 5
chr2_+_180716817 0.061


chr14_+_56159102 0.058 NM_028994
Pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr14_+_61351770 0.058 Spata13
spermatogenesis associated 13
chrX_-_98280689 0.050 NM_007515
Slc7a3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr6_+_88052091 0.049


chr8_+_59990639 0.048 NM_008252
Hmgb2
high mobility group box 2
chr13_+_46060591 0.044 5033430I15Rik
RIKEN cDNA 5033430I15 gene
chr5_-_37087261 0.043 D5Ertd579e
DNA segment, Chr 5, ERATO Doi 579, expressed
chr12_-_85534964 0.042 NM_001163502
C130039O16Rik
RIKEN cDNA C130039O16 gene
chr12_+_45412878 0.042 Pnpla8
patatin-like phospholipase domain containing 8
chr14_+_76245136 0.041 Tpt1
tumor protein, translationally-controlled 1
chr5_-_135103569 0.040


chr9_+_92502076 0.039


chr3_-_37024751 0.038 NM_008366
Il2
interleukin 2
chr2_-_105234998 0.037 Rcn1
reticulocalbin 1
chr15_+_65703468 0.033 Efr3a
EFR3 homolog A (S. cerevisiae)
chr9_+_21639937 0.033 NM_001080940
Gm6484
predicted gene 6484
chr12_-_86097486 0.033


chr2_-_30816439 0.031


chr11_+_78085325 0.031 2610507B11Rik
RIKEN cDNA 2610507B11 gene
chr10_+_126727846 0.028 NM_007837
Ddit3
DNA-damage inducible transcript 3
chr15_-_96472600 0.026 NM_001166456
Slc38a1
solute carrier family 38, member 1
chr18_+_32594823 0.024 Bin1
bridging integrator 1
chr13_-_43295201 0.024 Gfod1
glucose-fructose oxidoreductase domain containing 1
chr2_+_88231404 0.023 NM_001011868
Olfr1178
olfactory receptor 1178
chr7_+_110368156 0.022 NM_207143
Olfr594
olfactory receptor 594
chr12_-_4344470 0.022 Ncoa1
nuclear receptor coactivator 1
chr8_+_35228215 0.020


chr4_+_149494799 0.017 Slc2a5
solute carrier family 2 (facilitated glucose transporter), member 5
chr3_-_51323311 0.017 Setd7
SET domain containing (lysine methyltransferase) 7
chr7_+_35905996 0.015 Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr12_-_110099368 0.014


chr8_+_35224310 0.012 Tmem66
transmembrane protein 66
chr9_-_39380841 0.010 NM_146508
Olfr959
olfactory receptor 959
chr9_-_7932402 0.010 Yap1
yes-associated protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
170.12 2.76e-03 GO:0051004 regulation of lipoprotein lipase activity
145.84 3.77e-03 GO:0006953 acute-phase response
92.84 9.41e-03 GO:0002526 acute inflammatory response
48.11 3.52e-02 GO:0060191 regulation of lipase activity
14.11 4.32e-02 GO:0080134 regulation of response to stress

Nothing significant found in compartment category.

Nothing significant found in function category.