• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: E2F1..5.p2

Z-value: 4.553

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Top targets:

Promoter	Score	Refseq	Gene	Description
chr12_+_25393083	34.477	NM_009104	Rrm2	ribonucleotide reductase M2
chr2_-_154395469	34.110	NM_007891	E2f1	E2F transcription factor 1
chr15_-_57966551	33.015	NM_027435	Atad2	ATPase family, AAA domain containing 2
chr9_+_44142772	28.174	NM_010436	H2afx	H2A histone family, member X
chr1_-_20810238	27.321	NM_008563	Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)
chr8_+_77633426	25.835	NM_008566	Mcm5	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr4_+_126234210	25.640	NM_175554	Clspn	claspin homolog (Xenopus laevis)
chr5_-_138613028	24.221	NM_008568	Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)
chr13_+_22135065	23.086	NM_178198	Hist1h2bj	histone cluster 1, H2bj
chr10_+_110182506	22.851	NM_178609	E2f7	E2F transcription factor 7
chr2_+_72314235	22.812	NM_025866	Cdca7	cell division cycle associated 7
chr13_+_21813912	19.916	NM_178200	Hist1h2bm	histone cluster 1, H2bm
chr1_-_130256055	19.272	NM_008567	Mcm6	minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr6_-_88848650	18.923	NM_008564	Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr13_-_64254466	18.550	NM_175494	Zfp367	zinc finger protein 367
chr10_-_68815606	17.287	NM_007659	Cdk1	cyclin-dependent kinase 1
chr16_-_18248701	17.233	NM_011239	Ranbp1	RAN binding protein 1
chr4_+_98590642	16.988		Usp1	ubiquitin specific peptidase 1
chr2_-_157030236	16.983	NM_001139516 NM_011249	Rbl1	retinoblastoma-like 1 (p107)
chr9_-_36534167	16.618	NM_007691	Chek1	checkpoint kinase 1 homolog (S. pombe)
chr19_-_5964121	16.139		Pola2	polymerase (DNA directed), alpha 2
chr14_-_104867215	16.128	NM_011143	Pou4f1	POU domain, class 4, transcription factor 1
chr14_-_22806999	15.027		Zfp503	zinc finger protein 503
chr13_+_22127689	14.808	NM_175665	Hist1h2bk	histone cluster 1, H2bk
chr9_+_122860175	14.705	NM_010620	Kif15	kinesin family member 15
chr11_+_98769162	14.318	NM_001025779	Cdc6	cell division cycle 6 homolog (S. cerevisiae)
chr13_-_22134795	14.195	NM_178186	Hist1h2ag Hist1h2ai	histone cluster 1, H2ag histone cluster 1, H2ai
chr5_+_89194155	14.138		Dck	deoxycytidine kinase
chr13_-_23837389	14.093	NM_175653	Hist1h3c	histone cluster 1, H3c
chr17_+_56442759	13.810	NM_001111079 NM_010931	Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1
chr13_-_24853723	13.544	NM_020567	Gmnn	geminin
chr10_-_20880559	13.483	NM_001198914 NM_010848	Myb	myeloblastosis oncogene
chr10_+_4541075	13.367	NM_025995	Fbxo5	F-box protein 5
chr2_+_118938549	13.359	NM_011234	Rad51	RAD51 homolog (S. cerevisiae)
chr2_+_162880370	12.954	NM_008652	Mybl2	myeloblastosis oncogene-like 2
chr13_+_93125151	12.936		Dhfr	dihydrofolate reductase
chr19_+_39005433	12.894	NM_008234	Hells	helicase, lymphoid specific
chr1_+_74552794	12.815		Rqcd1	rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr9_+_54612599	12.463	NM_013496	Crabp1	cellular retinoic acid binding protein I
chr12_+_34642516	12.286	NM_011658	Twist1	twist homolog 1 (Drosophila)
chrX_-_90877453	12.002	NM_008892	Pola1	polymerase (DNA directed), alpha 1
chr1_-_193399352	11.974		Dtl	denticleless homolog (Drosophila)
chr13_-_22127419	11.795	NM_175659	Hist1h2ah	histone cluster 1, H2ah
chr3_+_97817440	11.767	NM_010928	Notch2	Notch gene homolog 2 (Drosophila)
chr2_-_113688771	11.727	NM_181416	Arhgap11a	Rho GTPase activating protein 11A
chr12_-_70329149	11.388	NM_011133	Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)
chr14_+_70008874	11.056		Loxl2	lysyl oxidase-like 2
chr2_+_150735306	11.054	NM_001163476 NM_027014	Gins1	GINS complex subunit 1 (Psf1 homolog)
chr10_+_127669118	10.796	NM_001136082 NM_001164080 NM_001164081	Timeless	timeless homolog (Drosophila)
chr15_-_9070066	10.792	NM_013787 NM_145468	Skp2	S-phase kinase-associated protein 2 (p45)
chrX_-_7651846	10.571	NM_011514	Suv39h1	suppressor of variegation 3-9 homolog 1 (Drosophila)
chr13_-_55431027	10.398	NM_016662	Mxd3	Max dimerization protein 3
chr11_+_98769122	10.353		Cdc6	cell division cycle 6 homolog (S. cerevisiae)
chr17_+_56443766	10.179		Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1
chrX_+_148450970	10.178	NM_019710	Smc1a	structural maintenance of chromosomes 1A
chr4_+_98590565	10.136		Usp1	ubiquitin specific peptidase 1
chr13_+_21879356	10.098	NM_178202	Hist1h2bp	histone cluster 1, H2bp
chr13_-_23853025	9.986	NM_178192	Hist1h4a	histone cluster 1, H4a
chr1_+_159342882	9.941		2810025M15Rik	RIKEN cDNA 2810025M15 gene
chr2_+_38206759	9.816	NM_010710	Lhx2	LIM homeobox protein 2
chr4_+_134066913	9.791	NM_001081099	2610002D18Rik	RIKEN cDNA 2610002D18 gene
chr7_-_142908061	9.611	NM_001081117	Mki67	antigen identified by monoclonal antibody Ki 67
chr3_-_145312928	9.610	NM_010516	Cyr61	cysteine rich protein 61
chr14_-_21208006	9.592	NM_134081	Dnajc9	DnaJ (Hsp40) homolog, subfamily C, member 9
chr7_-_51804139	9.473	NM_011131	Pold1	polymerase (DNA directed), delta 1, catalytic subunit
chr8_-_123112974	9.468	NM_178856	Gins2	GINS complex subunit 2 (Psf2 homolog)
chr11_+_79902901	9.416	NM_001029856	Atad5	ATPase family, AAA domain containing 5
chr4_+_135728188	9.399	NM_177733	E2f2	E2F transcription factor 2
chrX_+_39503858	9.304	NM_021465	Stag2	stromal antigen 2
chr2_+_53051140	9.289		Arl6ip6	ADP-ribosylation factor-like 6 interacting protein 6
chr1_+_133807034	9.288	NM_001145804 NM_175294	Nucks1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr9_+_64129387	9.280	NM_025372	Tipin	timeless interacting protein
chr9_+_109778051	9.221	NM_007658	Cdc25a	cell division cycle 25 homolog A (S. pombe)
chr7_-_56136367	8.856		E2f8	E2F transcription factor 8
chr5_+_46061125	8.734	NM_019438	Ncapg	non-SMC condensin I complex, subunit G
chr11_-_86621074	8.723		Dhx40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr7_+_117265568	8.663	NM_009516	Wee1	WEE 1 homolog 1 (S. pombe)
chr4_+_114672722	8.601	NM_009185	Stil	Scl/Tal1 interrupting locus
chr7_-_56136965	8.546		E2f8	E2F transcription factor 8
chr12_-_11272479	8.530	NM_177331	Gen1	Gen homolog 1, endonuclease (Drosophila)
chr15_-_97923632	8.502	NM_144851	Senp1	SUMO1/sentrin specific peptidase 1
chr16_-_4559511	8.483	NM_031182	Tcfap4	transcription factor AP4
chr16_-_18811669	8.465	NM_001161623	Cdc45	cell division cycle 45 homolog (S. cerevisiae)
chr8_-_123112925	8.464		Gins2	GINS complex subunit 2 (Psf2 homolog)
chr13_-_21875234	8.447	NM_178207	Hist1h3i	histone cluster 1, H3i
chr15_-_54921986	8.441	NM_183089	Dscc1	defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr3_-_88214230	8.384	NM_025928	Pmf1	polyamine-modulated factor 1
chr9_+_65738129	8.316	NM_026515	2810417H13Rik	RIKEN cDNA 2810417H13 gene
chr12_+_117643874	8.211	NM_133762	Ncapg2	non-SMC condensin II complex, subunit G2
chr10_+_4541138	8.140		Fbxo5	F-box protein 5
chr14_-_48037815	7.982		Dlgap5	discs, large (Drosophila) homolog-associated protein 5
chr9_+_103207488	7.968	NM_176979	Topbp1	topoisomerase (DNA) II binding protein 1
chr7_-_56892061	7.937	NM_001005232	Dbx1	developing brain homeobox 1
chr15_+_78858872	7.926		H1f0	H1 histone family, member 0
chr4_+_135412062	7.773		Srsf10	serine/arginine-rich splicing factor 10
chr17_+_29627697	7.764		Pim1	proviral integration site 1
chr17_+_88374355	7.761	NM_010830	Msh6	mutS homolog 6 (E. coli)
chr11_-_50105794	7.736	NM_175334	Maml1	mastermind like 1 (Drosophila)
chr13_-_101545800	7.700	NM_021886	Cenph	centromere protein H
chr18_-_43597890	7.648		Dpysl3	dihydropyrimidinase-like 3
chr1_-_71699671	7.629	NM_010233	Fn1	fibronectin 1
chr14_+_31832374	7.601		Pbrm1	polybromo 1
chr6_-_47544925	7.492	NM_001146689 NM_007971	Ezh2	enhancer of zeste homolog 2 (Drosophila)
chr5_+_110715337	7.386	NM_011132	Pole	polymerase (DNA directed), epsilon
chr6_+_51420581	7.385	NM_007624	Cbx3	chromobox homolog 3 (Drosophila HP1 gamma)
chr13_+_23625779	7.363	NM_175661	Hist1h2af	histone cluster 1, H2af
chr13_-_23654226	7.362	NM_178205	Hist1h3e	histone cluster 1, H3e
chr8_+_13338741	7.319		Tfdp1	transcription factor Dp 1
chr4_+_135412028	7.255		Srsf10	serine/arginine-rich splicing factor 10
chr1_-_183772442	7.249	NM_133815	Lbr	lamin B receptor
chr10_+_24315247	7.082	NM_010217	Ctgf	connective tissue growth factor
chr5_-_65726802	7.059	NM_011258	Rfc1	replication factor C (activator 1) 1
chr11_+_101329457	6.999		Rnd2	Rho family GTPase 2
chr8_+_125091925	6.907		Cdt1	chromatin licensing and DNA replication factor 1
chr15_+_55388962	6.907	NM_001168250 NM_134092	Mtbp	Mdm2, transformed 3T3 cell double minute p53 binding protein
chr4_+_11118855	6.900	NM_009830	Ccne2	cyclin E2
chr6_+_4697305	6.867	NM_001040611 NM_130877	Peg10	paternally expressed 10
chr1_-_71149409	6.853	NM_007525	Bard1	BRCA1 associated RING domain 1
chr5_+_114580397	6.749	NM_001040691	Ung	uracil DNA glycosylase
chr1_-_169215189	6.696		Uck2	uridine-cytidine kinase 2
chr13_-_47201478	6.653	NM_025900	Dek	DEK oncogene (DNA binding)
chr4_+_135411923	6.588	NM_001080387 NM_010178	Srsf10	serine/arginine-rich splicing factor 10
chr6_+_113481672	6.568	NM_001033244	Fancd2	Fanconi anemia, complementation group D2
chr17_+_23863280	6.548	NM_023058	Pkmyt1	protein kinase, membrane associated tyrosine/threonine 1
chr17_+_56443710	6.438	NM_001111078 NM_001111080	Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1
chr5_-_137043355	6.406
chr4_+_108252056	6.383	NM_011015	Orc1	origin recognition complex, subunit 1
chr17_-_35653683	6.347	NM_001163763 NM_001163764 NM_025674	Tcf19	transcription factor 19
chr18_+_56867378	6.329	NM_010721	Lmnb1	lamin B1
chr4_+_132324212	6.317	NM_011284	Rpa2	replication protein A2
chr4_+_148178500	6.288	NM_001159344 NM_027195	Casz1	castor homolog 1, zinc finger (Drosophila)
chr2_+_132641920	6.210	NM_025676	Mcm8	minichromosome maintenance deficient 8 (S. cerevisiae)
chr9_-_20757236	6.210	NM_010066	Dnmt1	DNA methyltransferase (cytosine-5) 1
chr11_-_6344354	6.186		H2afv	H2A histone family, member V
chr7_-_144506112	6.165	NM_001113414 NM_001113415 NM_010096	Ebf3	early B-cell factor 3
chr2_+_84877598	6.153	NM_001136081	Ssrp1	structure specific recognition protein 1
chr9_+_100544034	6.115	NM_009282	Stag1	stromal antigen 1
chr3_+_41367304	6.029	NM_172303	Phf17	PHD finger protein 17
chr4_-_22415444	5.987		Pou3f2	POU domain, class 3, transcription factor 2
chr9_+_65478364	5.982	NM_028030	Rbpms2	RNA binding protein with multiple splicing 2
chr7_-_107269928	5.947	NM_133692	Pold3	polymerase (DNA-directed), delta 3, accessory subunit
chr10_-_78054639	5.932	NM_027875	Syde1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr9_+_100543993	5.921		Stag1	stromal antigen 1
chr1_-_158404299	5.921	NM_009230	Soat1	sterol O-acyltransferase 1
chr4_-_148511650	5.769	NM_027263	Apitd1	apoptosis-inducing, TAF9-like domain 1
chr9_+_107853281	5.746	NM_011634	Traip	TRAF-interacting protein
chr2_-_132078887	5.743	NM_011045	Pcna	proliferating cell nuclear antigen
chr15_-_81702298	5.742	NM_026737	Phf5a	PHD finger protein 5A
chr3_+_95908422	5.734	NM_001025613 NM_001025614	Otud7b	OTU domain containing 7B
chr6_-_51419893	5.727		Hnrnpa2b1	heterogeneous nuclear ribonucleoprotein A2/B1
chr9_-_20896441	5.727		Raver1	ribonucleoprotein, PTB-binding 1
chr11_+_79806552	5.713	NM_001163018 NM_199196	Suz12	suppressor of zeste 12 homolog (Drosophila)
chr14_-_48037874	5.682		Dlgap5	discs, large (Drosophila) homolog-associated protein 5
chr10_+_107769093	5.673	NM_054056	Pawr	PRKC, apoptosis, WT1, regulator
chr2_+_84877325	5.600	NM_182990	Ssrp1	structure specific recognition protein 1
chr3_+_116297899	5.589	NM_028349	Sass6	spindle assembly 6 homolog (C. elegans)
chr6_-_4697009	5.465	NM_001130188 NM_001130189 NM_001130190 NM_001130191 NM_011360	Sgce	sarcoglycan, epsilon
chr16_-_22265901	5.457	NM_009186	Tra2b	transformer 2 beta homolog (Drosophila)
chr2_+_121781736	5.455		Ctdspl2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr13_-_112280018	5.394	NM_001122963 NM_028487	Gpbp1	GC-rich promoter binding protein 1
chr2_+_129626252	5.316	NM_001038635 NM_183262	Stk35	serine/threonine kinase 35
chr13_-_55463928	5.302		Lman2	lectin, mannose-binding 2
chr8_+_98157458	5.280	NM_030198	Gins3	GINS complex subunit 3 (Psf3 homolog)
chr10_+_5958432	5.273	NM_001033466	Zbtb2	zinc finger and BTB domain containing 2
chr4_-_10934608	5.270	NM_175175	Plekhf2	pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr6_-_125141525	5.189	NM_146171	Ncapd2	non-SMC condensin I complex, subunit D2
chr2_-_164705231	5.166		4930445K14Rik	RIKEN cDNA 4930445K14 gene
chr17_+_28938070	5.162	NM_001081315	Brpf3	bromodomain and PHD finger containing, 3
chr13_+_21845991	5.143	NM_178201	Hist1h2bn	histone cluster 1, H2bn
chr10_-_79896330	5.140		Tcf3	transcription factor 3
chr4_+_107040647	5.135		Tmem48	transmembrane protein 48
chr9_-_13631482	5.116	NM_026665	Cep57	centrosomal protein 57
chrX_+_148451021	5.098		Smc1a	structural maintenance of chromosomes 1A
chr19_-_47538898	5.091	NM_001164717 NM_008018	Sh3pxd2a	SH3 and PX domains 2A
chr6_-_87931475	5.072	NM_198622	H1fx	H1 histone family, member X
chr8_-_126506732	5.028		Abcb10	ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr1_+_177810908	5.019	NM_012012	Exo1	exonuclease 1
chr4_+_128670474	4.970	NM_001033966 NM_016895	Ak2	adenylate kinase 2
chr6_-_134847832	4.959	NM_001167695 NM_001167696 NM_001167693 NM_001167694 NM_001167700	Gpr19	G protein-coupled receptor 19
chr3_-_96067233	4.955	NM_033596	Hist2h4	histone cluster 2, H4
chr10_+_127740390	4.921	NM_133992	Pan2	PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr3_-_83959616	4.904	NM_029797	Mnd1	meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr16_-_4719058	4.897	NM_026393	Nmral1	NmrA-like family domain containing 1
chr10_-_127962914	4.888	NM_011843	Esyt1	extended synaptotagmin-like protein 1
chr1_-_169215216	4.857	NM_030724	Uck2	uridine-cytidine kinase 2
chr5_+_140019846	4.844	NM_013702	Uncx	UNC homeobox
chr4_+_120339167	4.832	NM_019563	Cited4	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr15_+_89186142	4.825	NM_001115132 NM_025795	Ncaph2	non-SMC condensin II complex, subunit H2
chr14_-_66452720	4.798	NM_028039	Esco2	establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr13_+_23666249	4.782	NM_178188	Hist1h2ad Hist1h2ai	histone cluster 1, H2ad histone cluster 1, H2ai
chr17_-_26645403	4.781	NM_013642	Dusp1	dual specificity phosphatase 1
chr15_-_96471920	4.765		Slc38a1	solute carrier family 38, member 1
chr9_-_20896404	4.745	NM_027911	Raver1	ribonucleoprotein, PTB-binding 1
chr10_+_12810593	4.724	NM_009538	Plagl1	pleiomorphic adenoma gene-like 1
chrX_+_17739762	4.711	NM_009483	Kdm6a	4lysine (K)-specific demethylase 6A
chr11_-_87217940	4.711	NM_053269	Rad51c	RAD51 homolog c (S. cerevisiae)
chr15_+_8059306	4.697	NM_133227	Nup155	nucleoporin 155
chr10_-_79502432	4.695		Polr2e	polymerase (RNA) II (DNA directed) polypeptide E
chr3_-_127256215	4.683	NM_138593	Larp7	La ribonucleoprotein domain family, member 7
chr4_+_131429522	4.638	NM_020587	Srsf4	serine/arginine-rich splicing factor 4

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.89	2.13e-48	GO:0090304	nucleic acid metabolic process
2.24	1.81e-46	GO:0044260	cellular macromolecule metabolic process
2.59	6.90e-44	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.42	2.82e-40	GO:0034641	cellular nitrogen compound metabolic process
2.06	4.89e-40	GO:0043170	macromolecule metabolic process
4.72	6.12e-39	GO:0007049	cell cycle
2.36	7.84e-39	GO:0006807	nitrogen compound metabolic process
5.92	1.04e-36	GO:0006259	DNA metabolic process
1.85	6.04e-35	GO:0044237	cellular metabolic process
10.84	4.57e-34	GO:0006260	DNA replication
1.80	1.66e-32	GO:0044238	primary metabolic process
1.65	1.27e-26	GO:0008152	metabolic process
2.43	4.18e-25	GO:0009059	macromolecule biosynthetic process
2.44	5.08e-25	GO:0034645	cellular macromolecule biosynthetic process
2.45	9.03e-25	GO:0016070	RNA metabolic process
5.09	2.71e-23	GO:0022403	cell cycle phase
2.28	8.31e-22	GO:0010467	gene expression
5.09	1.20e-21	GO:0006974	response to DNA damage stimulus
4.47	1.43e-20	GO:0051276	chromosome organization
2.24	1.51e-20	GO:0010556	regulation of macromolecule biosynthetic process
2.25	2.51e-20	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.09	3.70e-20	GO:0044249	cellular biosynthetic process
4.11	5.90e-20	GO:0022402	cell cycle process
2.05	1.52e-19	GO:0009058	biosynthetic process
1.98	1.18e-18	GO:0060255	regulation of macromolecule metabolic process
5.52	3.62e-18	GO:0006281	DNA repair
2.09	1.85e-17	GO:0009889	regulation of biosynthetic process
1.92	2.24e-17	GO:0031323	regulation of cellular metabolic process
2.09	3.52e-17	GO:0031326	regulation of cellular biosynthetic process
4.99	3.96e-17	GO:0051301	cell division
2.09	4.74e-17	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.07	1.33e-16	GO:0051171	regulation of nitrogen compound metabolic process
4.58	2.66e-16	GO:0000278	mitotic cell cycle
4.82	3.99e-16	GO:0000279	M phase
1.81	4.61e-16	GO:0019222	regulation of metabolic process
2.40	5.34e-16	GO:0032774	RNA biosynthetic process
1.88	8.05e-16	GO:0080090	regulation of primary metabolic process
3.53	9.31e-16	GO:0033554	cellular response to stress
2.38	1.33e-15	GO:0006351	transcription, DNA-dependent
1.30	2.52e-15	GO:0009987	cellular process
2.03	5.97e-15	GO:0010468	regulation of gene expression
4.01	1.77e-14	GO:0051726	regulation of cell cycle
2.51	1.78e-14	GO:0006996	organelle organization
2.10	1.95e-14	GO:0051252	regulation of RNA metabolic process
2.09	5.95e-14	GO:0006355	regulation of transcription, DNA-dependent
4.19	5.72e-13	GO:0006325	chromatin organization
2.07	8.12e-13	GO:0071841	cellular component organization or biogenesis at cellular level
7.81	1.22e-12	GO:0071103	DNA conformation change
5.17	4.91e-12	GO:0000087	M phase of mitotic cell cycle
12.59	8.31e-12	GO:0006261	DNA-dependent DNA replication
5.21	1.04e-11	GO:0010564	regulation of cell cycle process
5.13	1.57e-11	GO:0000280	nuclear division
5.13	1.57e-11	GO:0007067	mitosis
2.03	5.06e-11	GO:0071842	cellular component organization at cellular level
4.93	5.14e-11	GO:0048285	organelle fission
1.82	6.88e-11	GO:0071840	cellular component organization or biogenesis
3.35	1.09e-10	GO:0006396	RNA processing
30.66	2.20e-10	GO:0006270	DNA-dependent DNA replication initiation
4.36	8.29e-10	GO:0008380	RNA splicing
1.80	9.65e-10	GO:0016043	cellular component organization
3.95	1.57e-09	GO:0016568	chromatin modification
7.99	2.36e-09	GO:0006275	regulation of DNA replication
6.88	3.60e-09	GO:0007059	chromosome segregation
6.81	1.45e-08	GO:0051329	interphase of mitotic cell cycle
5.49	1.64e-08	GO:0051052	regulation of DNA metabolic process
6.62	2.57e-08	GO:0051325	interphase
1.80	6.24e-08	GO:0048522	positive regulation of cellular process
7.05	8.73e-08	GO:0006323	DNA packaging
2.67	2.91e-07	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.32	4.70e-07	GO:0044085	cellular component biogenesis
2.63	4.97e-07	GO:0051172	negative regulation of nitrogen compound metabolic process
4.48	5.44e-07	GO:0016569	covalent chromatin modification
1.82	7.93e-07	GO:0048523	negative regulation of cellular process
3.40	8.15e-07	GO:0016071	mRNA metabolic process
2.23	1.22e-06	GO:0009892	negative regulation of metabolic process
2.59	1.32e-06	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.50	1.96e-06	GO:0031327	negative regulation of cellular biosynthetic process
4.37	2.05e-06	GO:0016570	histone modification
2.27	2.17e-06	GO:0010605	negative regulation of macromolecule metabolic process
1.90	2.43e-06	GO:0043412	macromolecule modification
15.33	2.84e-06	GO:0007062	sister chromatid cohesion
1.67	3.45e-06	GO:0048518	positive regulation of biological process
10.71	4.14e-06	GO:0008156	negative regulation of DNA replication
2.44	4.42e-06	GO:0009890	negative regulation of biosynthetic process
1.91	4.86e-06	GO:0006464	protein modification process
2.48	5.09e-06	GO:0010558	negative regulation of macromolecule biosynthetic process
4.33	5.48e-06	GO:0007346	regulation of mitotic cell cycle
1.72	8.80e-06	GO:0048519	negative regulation of biological process
5.68	9.92e-06	GO:0071156	regulation of cell cycle arrest
2.27	1.38e-05	GO:0010557	positive regulation of macromolecule biosynthetic process
19.87	1.88e-05	GO:2000104	negative regulation of DNA-dependent DNA replication
3.41	2.59e-05	GO:0006397	mRNA processing
7.26	2.81e-05	GO:0071824	protein-DNA complex subunit organization
2.17	2.89e-05	GO:0031324	negative regulation of cellular metabolic process
14.34	4.43e-05	GO:0006297	nucleotide-excision repair, DNA gap filling
7.71	4.82e-05	GO:0051053	negative regulation of DNA metabolic process
2.15	5.56e-05	GO:0009891	positive regulation of biosynthetic process
11.36	6.60e-05	GO:0033261	regulation of S phase
17.03	7.73e-05	GO:0090329	regulation of DNA-dependent DNA replication
1.96	8.25e-05	GO:0010604	positive regulation of macromolecule metabolic process
5.62	8.96e-05	GO:0000075	cell cycle checkpoint
2.43	1.29e-04	GO:0043933	macromolecular complex subunit organization
7.05	1.41e-04	GO:0065004	protein-DNA complex assembly
2.11	1.62e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.92	1.69e-04	GO:0031325	positive regulation of cellular metabolic process
20.44	1.76e-04	GO:0000084	S phase of mitotic cell cycle
2.17	2.11e-04	GO:0022607	cellular component assembly
1.67	2.22e-04	GO:0044267	cellular protein metabolic process
7.35	3.09e-04	GO:0031570	DNA integrity checkpoint
2.14	3.21e-04	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
6.49	3.69e-04	GO:0006333	chromatin assembly or disassembly
5.06	3.71e-04	GO:0018205	peptidyl-lysine modification
18.58	3.78e-04	GO:0051320	S phase
18.58	3.78e-04	GO:0071897	DNA biosynthetic process
1.85	4.23e-04	GO:0009893	positive regulation of metabolic process
7.07	4.69e-04	GO:0000082	G1/S transition of mitotic cell cycle
2.36	5.40e-04	GO:0051253	negative regulation of RNA metabolic process
4.91	5.49e-04	GO:0007126	meiosis
4.91	5.49e-04	GO:0051327	M phase of meiotic cell cycle
4.87	6.23e-04	GO:0051321	meiotic cell cycle
24.33	6.38e-04	GO:0007064	mitotic sister chromatid cohesion
2.09	6.91e-04	GO:0051173	positive regulation of nitrogen compound metabolic process
2.39	7.62e-04	GO:0065003	macromolecular complex assembly
6.69	8.45e-04	GO:0006289	nucleotide-excision repair
6.69	8.45e-04	GO:0031497	chromatin assembly
2.27	8.50e-04	GO:0010629	negative regulation of gene expression
2.06	1.09e-03	GO:0042127	regulation of cell proliferation
11.92	1.50e-03	GO:0032392	DNA geometric change
2.28	2.46e-03	GO:0045892	negative regulation of transcription, DNA-dependent
4.63	2.79e-03	GO:0006310	DNA recombination
5.31	3.50e-03	GO:0050657	nucleic acid transport
5.31	3.50e-03	GO:0050658	RNA transport
5.31	3.50e-03	GO:0051236	establishment of RNA localization
2.09	3.97e-03	GO:0051254	positive regulation of RNA metabolic process
5.24	4.02e-03	GO:0006473	protein acetylation
2.38	4.58e-03	GO:0010942	positive regulation of cell death
2.04	5.00e-03	GO:0010628	positive regulation of gene expression
5.11	5.29e-03	GO:0006403	RNA localization
6.19	5.81e-03	GO:0033044	regulation of chromosome organization
2.79	6.09e-03	GO:0034621	cellular macromolecular complex subunit organization
17.03	7.12e-03	GO:0006268	DNA unwinding involved in replication
5.43	7.33e-03	GO:0051028	mRNA transport
5.98	8.14e-03	GO:0034728	nucleosome organization
6.52	1.14e-02	GO:0000077	DNA damage checkpoint
4.39	1.19e-02	GO:0043414	macromolecule methylation
11.36	1.27e-02	GO:0032508	DNA duplex unwinding
4.70	1.29e-02	GO:0040029	regulation of gene expression, epigenetic
2.03	1.41e-02	GO:0045893	positive regulation of transcription, DNA-dependent
4.04	1.41e-02	GO:0032259	methylation
8.83	1.43e-02	GO:0006284	base-excision repair
22.71	1.57e-02	GO:0000076	DNA replication checkpoint
22.71	1.57e-02	GO:0032297	negative regulation of DNA-dependent DNA replication initiation
2.31	1.62e-02	GO:0043065	positive regulation of apoptosis
1.23	1.81e-02	GO:0050794	regulation of cellular process
2.29	1.92e-02	GO:0043068	positive regulation of programmed cell death
2.19	1.95e-02	GO:0071844	cellular component assembly at cellular level
4.49	2.07e-02	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
6.99	2.15e-02	GO:0043687	post-translational protein modification
4.44	2.32e-02	GO:0043543	protein acylation
2.78	2.51e-02	GO:0034622	cellular macromolecular complex assembly
1.84	2.51e-02	GO:0010941	regulation of cell death
10.22	2.53e-02	GO:0007090	regulation of S phase of mitotic cell cycle
1.64	2.82e-02	GO:0006950	response to stress
34.06	3.76e-02	GO:0006975	DNA damage induced protein phosphorylation
34.06	3.76e-02	GO:0010216	maintenance of DNA methylation
34.06	3.76e-02	GO:0032467	positive regulation of cytokinesis
1.84	3.77e-02	GO:0042981	regulation of apoptosis
2.69	4.16e-02	GO:0018193	peptidyl-amino acid modification
1.46	4.86e-02	GO:0019538	protein metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.55	1.65e-79	GO:0005634	nucleus
3.74	5.88e-58	GO:0044428	nuclear part
1.76	3.42e-47	GO:0043231	intracellular membrane-bounded organelle
1.76	6.27e-47	GO:0043227	membrane-bounded organelle
3.77	1.42e-46	GO:0031981	nuclear lumen
3.38	2.06e-43	GO:0031974	membrane-enclosed lumen
3.42	2.37e-43	GO:0070013	intracellular organelle lumen
1.65	2.98e-43	GO:0043226	organelle
3.41	3.03e-43	GO:0043233	organelle lumen
1.66	4.24e-43	GO:0043229	intracellular organelle
2.24	4.81e-39	GO:0044446	intracellular organelle part
1.51	1.34e-37	GO:0044424	intracellular part
2.20	1.63e-37	GO:0044422	organelle part
4.06	7.96e-37	GO:0005654	nucleoplasm
6.06	8.74e-37	GO:0005694	chromosome
1.50	8.98e-37	GO:0005622	intracellular
6.07	7.83e-34	GO:0044427	chromosomal part
2.21	5.12e-19	GO:0043228	non-membrane-bounded organelle
2.21	5.12e-19	GO:0043232	intracellular non-membrane-bounded organelle
1.98	1.03e-18	GO:0032991	macromolecular complex
6.17	4.00e-17	GO:0000785	chromatin
6.40	1.01e-15	GO:0044454	nuclear chromosome part
3.40	1.11e-15	GO:0044451	nucleoplasm part
5.93	1.42e-15	GO:0000228	nuclear chromosome
1.78	9.98e-10	GO:0043234	protein complex
6.67	1.22e-08	GO:0000790	nuclear chromatin
12.77	1.24e-08	GO:0005657	replication fork
6.47	2.13e-08	GO:0000793	condensed chromosome
5.30	1.09e-07	GO:0000775	chromosome, centromeric region
1.14	3.70e-07	GO:0005623	cell
1.14	3.70e-07	GO:0044464	cell part
2.80	3.08e-06	GO:0030529	ribonucleoprotein complex
4.83	3.57e-06	GO:0005681	spliceosomal complex
34.06	5.54e-06	GO:0042555	MCM complex
6.12	1.41e-05	GO:0032993	protein-DNA complex
6.93	2.99e-05	GO:0034708	methyltransferase complex
6.93	2.99e-05	GO:0035097	histone methyltransferase complex
2.89	3.63e-05	GO:0005730	nucleolus
6.49	6.40e-05	GO:0000792	heterochromatin
5.54	1.40e-04	GO:0071013	catalytic step 2 spliceosome
18.92	6.33e-04	GO:0035098	ESC/E(Z) complex
3.48	6.49e-04	GO:0005635	nuclear envelope
12.77	1.00e-03	GO:0043596	nuclear replication fork
14.19	3.70e-03	GO:0030894	replisome
14.19	3.70e-03	GO:0043601	nuclear replisome
3.68	3.79e-03	GO:0016604	nuclear body
4.63	6.16e-03	GO:0016585	chromatin remodeling complex
3.92	7.08e-03	GO:0005819	spindle
5.56	2.11e-02	GO:0000786	nucleosome
25.55	2.55e-02	GO:0000444	MIS12/MIND type complex
6.28	2.67e-02	GO:0005720	nuclear heterochromatin
8.97	4.58e-02	GO:0031519	PcG protein complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.55	6.11e-33	GO:0003676	nucleic acid binding
2.79	2.94e-27	GO:0003677	DNA binding
1.39	1.76e-20	GO:0005488	binding
1.49	4.74e-10	GO:0005515	protein binding
1.93	7.41e-10	GO:0000166	nucleotide binding
4.36	1.03e-07	GO:0003682	chromatin binding
4.28	3.40e-07	GO:0043566	structure-specific DNA binding
8.18	5.53e-06	GO:0003697	single-stranded DNA binding
1.81	9.53e-06	GO:0035639	purine ribonucleoside triphosphate binding
1.90	1.14e-05	GO:0032559	adenyl ribonucleotide binding
1.91	1.14e-05	GO:0005524	ATP binding
1.79	1.19e-05	GO:0032555	purine ribonucleotide binding
1.79	1.22e-05	GO:0032553	ribonucleotide binding
1.89	1.41e-05	GO:0030554	adenyl nucleotide binding
1.79	1.44e-05	GO:0017076	purine nucleotide binding
2.10	8.40e-05	GO:0030528	transcription regulator activity
5.91	8.66e-05	GO:0042393	histone binding
2.19	1.57e-04	GO:0001071	nucleic acid binding transcription factor activity
2.19	1.57e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
2.98	1.70e-04	GO:0008134	transcription factor binding
21.29	3.87e-04	GO:0070888	E-box binding
9.40	4.53e-04	GO:0003887	DNA-directed DNA polymerase activity
2.00	4.69e-04	GO:0016772	transferase activity, transferring phosphorus-containing groups
8.52	1.03e-03	GO:0034061	DNA polymerase activity
2.03	5.06e-03	GO:0003723	RNA binding
1.61	6.59e-03	GO:0016740	transferase activity
1.91	8.04e-03	GO:0019899	enzyme binding
1.59	1.74e-02	GO:0046914	transition metal ion binding
3.89	2.05e-02	GO:0016779	nucleotidyltransferase activity
1.65	2.28e-02	GO:0008270	zinc ion binding
15.14	2.86e-02	GO:0019206	nucleoside kinase activity
25.55	3.42e-02	GO:0017056	structural constituent of nuclear pore