Motif ID: EGR1..3.p2

Z-value: 1.537

Transcription factors associated with EGR1..3.p2:

NameEntrezDescription
Egr1 13653 early growth response 1
Egr2 13654 early growth response 2
Egr3 13655 early growth response 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Egr1chr18_+_35021288-0.076.8e-01Click!


Activity profile for motif EGR1..3.p2.

activity profile for motif EGR1..3.p2


Sorted Z-values histogram for motif EGR1..3.p2

Sorted Z-values for motif EGR1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EGR1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr11_-_5965555 9.593 Camk2b
calcium/calmodulin-dependent protein kinase II, beta
chrX_-_70905062 9.229 NM_012040
Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr11_-_5965626 8.958 Camk2b
calcium/calmodulin-dependent protein kinase II, beta
chr10_-_108447996 7.241 Syt1
synaptotagmin I
chr3_+_28162135 7.241 NM_001163007
NM_001163008
NM_001163009
NM_026910
Tnik



TRAF2 and NCK interacting kinase



chr10_-_108447894 6.710 Syt1
synaptotagmin I
chr10_-_108448003 6.595 Syt1
synaptotagmin I
chr11_+_68902025 6.191 NM_009497
Vamp2
vesicle-associated membrane protein 2
chr11_+_119804400 5.639 NM_001037754
NM_001037755
NM_130862
Baiap2


brain-specific angiogenesis inhibitor 1-associated protein 2


chrX_-_20498021 5.439 NM_001110780
NM_013680
Syn1

synapsin I

chr10_+_79179326 5.379 NM_008226
Hcn2
hyperpolarization-activated, cyclic nucleotide-gated K+ 2
chr9_+_58430210 5.367 Nptn
neuroplastin
chr7_+_120351012 5.340 Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr3_+_53959956 4.909 NM_016984
Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr6_+_110595574 4.894 Grm7
glutamate receptor, metabotropic 7
chr15_+_79921725 4.738 NM_009303
NM_207708
Syngr1

synaptogyrin 1

chr1_-_157264398 4.676 NM_011273
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr2_-_79296732 4.519 NM_010894
Neurod1
neurogenic differentiation 1
chr13_+_118391270 4.490 Hcn1
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr11_+_68901989 4.419 Vamp2
vesicle-associated membrane protein 2
chr2_+_156439426 4.310 NM_146128
Dlgap4
discs, large homolog-associated protein 4 (Drosophila)
chr4_-_151235758 4.218 Camta1
calmodulin binding transcription activator 1
chr12_-_113146259 4.198 NM_011625
Ppp1r13b
protein phosphatase 1, regulatory (inhibitor) subunit 13B
chr9_+_69137694 4.137 Rora
RAR-related orphan receptor alpha
chrX_-_70905384 4.013 Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr7_-_31836457 3.928 NM_022007
Fxyd7
FXYD domain-containing ion transport regulator 7
chr10_-_108447674 3.920 NM_009306
Syt1
synaptotagmin I
chr10_+_122115755 3.904 NM_001110218
NM_176919
Ppm1h

protein phosphatase 1H (PP2C domain containing)

chr16_-_22439642 3.750 NM_023794
Etv5
ets variant gene 5
chr15_+_12047769 3.625 Zfr
zinc finger RNA binding protein
chr13_-_54850954 3.612 NM_012014
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr1_-_52290058 3.574 NM_001081081
NM_001113383
Gls

glutaminase

chr9_-_53823107 3.541 NM_177769
Elmod1
ELMO domain containing 1
chr4_+_129190824 3.500 NM_010807
Marcksl1
MARCKS-like 1
chr1_-_175297778 3.495 NM_053199
Cadm3
cell adhesion molecule 3
chr11_+_120582777 3.490 NM_133223
Rac3
RAS-related C3 botulinum substrate 3
chr9_+_58430031 3.463 NM_009145
Nptn
neuroplastin
chr6_+_105627738 3.410 NM_001109749
NM_173004
Cntn4

contactin 4

chr11_-_77303157 3.371 NM_172945
Ankrd13b
ankyrin repeat domain 13b
chr12_-_5382487 3.289 NM_001164493
Klhl29
kelch-like 29 (Drosophila)
chr1_+_137043277 3.288 NM_026823
Arl8a
ADP-ribosylation factor-like 8A
chrX_+_7215705 3.264 NM_009305
Syp
synaptophysin
chr15_+_32174546 3.241 NM_009154
Sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr6_-_124867962 3.227 NM_026988
Ptms
parathymosin
chr5_+_137994744 3.223 NM_031404
Actl6b
actin-like 6B
chr16_-_20621287 3.197 NM_028420
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr7_+_64846528 3.171 NM_008071
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr11_+_94871643 3.163 Samd14
sterile alpha motif domain containing 14
chr7_-_26460133 3.089 Tmem91
transmembrane protein 91
chr4_-_63707964 3.077 Tnc
tenascin C
chr18_+_59334993 3.076 NM_001081328
Chsy3
chondroitin sulfate synthase 3
chr7_-_54387695 3.064 Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr1_+_23768764 2.987 NM_172124
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr2_-_24618566 2.985 NM_001042528
NM_007579
Cacna1b

calcium channel, voltage-dependent, N type, alpha 1B subunit

chr19_+_60832080 2.963 Nanos1
nanos homolog 1 (Drosophila)
chr6_+_61130318 2.952 NM_001164316
NM_183310
Fam190a

family with sequence similarity 190, member A

chr9_-_86589782 2.932 NM_008615
Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr8_-_87324043 2.897 NM_001081982
NM_010906
Nfix

nuclear factor I/X

chr2_-_162486792 2.867 Ptprt
protein tyrosine phosphatase, receptor type, T
chr4_-_151235861 2.842 NM_001081557
NM_001195565
Camta1

calmodulin binding transcription activator 1

chr10_-_79602040 2.819 Dos
downstream of Stk11
chr3_-_57651409 2.800 Pfn2
profilin 2
chr7_-_134968017 2.794 NM_024414
Stx1b
syntaxin 1B
chr16_-_67621054 2.786 NM_001145977
NM_178721
Cadm2

cell adhesion molecule 2

chr16_+_91547266 2.777 NM_008338
Ifngr2
interferon gamma receptor 2
chr11_+_105451296 2.748 NM_181071
Tanc2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr4_+_137806293 2.728 NM_001099631
Sh2d5
SH2 domain containing 5
chr4_+_151552208 2.686 NM_133348
AU014716
Acot7
expressed sequence AU014716
acyl-CoA thioesterase 7
chr7_+_28438881 2.671 NM_028417
Ttc9b
tetratricopeptide repeat domain 9B
chr9_-_58052107 2.667 NM_001161541
Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr11_+_98603186 2.630 NM_178060
Thra
thyroid hormone receptor alpha
chr17_+_46390828 2.624 NM_001111142
Gm88
predicted gene 88
chr6_+_49772688 2.623 NM_023456
Npy
neuropeptide Y
chr1_+_74901489 2.615 NM_009872
Cdk5r2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr4_-_136512727 2.615 NM_007939
Epha8
Eph receptor A8
chr11_-_5965743 2.611 NM_001174053
NM_001174054
NM_007595
Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr5_-_139605617 2.604 NM_008923
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr4_+_42930076 2.590 NM_172690
N28178
expressed sequence N28178
chr15_+_54402914 2.551 NM_178920
Mal2
mal, T-cell differentiation protein 2
chr4_-_128798481 2.548 NM_010471
Hpca
hippocalcin
chr9_-_53822931 2.542 Elmod1
ELMO domain containing 1
chr11_-_87800799 2.502 NM_026556
Dynll2
dynein light chain LC8-type 2
chr10_-_115910911 2.498 Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr4_+_104040160 2.446 NM_010014
NM_177259
Dab1

disabled homolog 1 (Drosophila)

chr5_+_43625165 2.425 Cpeb2
cytoplasmic polyadenylation element binding protein 2
chrX_+_158154967 2.424 NM_001103367
Rai2
retinoic acid induced 2
chr17_+_24625530 2.422 Caskin1
CASK interacting protein 1
chr13_-_6647924 2.409 NM_019703
Pfkp
phosphofructokinase, platelet
chr8_+_86939262 2.392 NM_007578
Cacna1a
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr2_+_155601077 2.379 NM_010808
Mmp24
matrix metallopeptidase 24
chr15_-_75397243 2.367 NM_001135688
Ly6h
lymphocyte antigen 6 complex, locus H
chr12_+_111685371 2.294 NM_001135001
Ppp2r5c
protein phosphatase 2, regulatory subunit B (B56), gamma isoform
chr10_+_126515962 2.286 NM_001033263
Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr4_+_28740280 2.283 NM_001122889
NM_010141
Epha7

Eph receptor A7

chr6_-_124867732 2.270


chr11_-_102308966 2.268 NM_199200
Fam171a2
family with sequence similarity 171, member A2
chr4_+_49072327 2.251 NM_178756
E130309F12Rik
RIKEN cDNA E130309F12 gene
chr9_-_102256962 2.240 NM_001168296
NM_173447
Ephb1

Eph receptor B1

chr11_+_80290509 2.224 NM_009871
Cdk5r1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr12_+_117724182 2.207 NM_011215
Ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr4_+_49072138 2.200 E130309F12Rik
RIKEN cDNA E130309F12 gene
chr4_+_28740314 2.166 Epha7
Eph receptor A7
chr11_-_74537303 2.133 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr15_+_99125666 2.126 Prpf40b
PRP40 pre-mRNA processing factor 40 homolog B (yeast)
chr4_+_126846429 2.110 NM_198618
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr6_-_18464737 2.104 Cttnbp2
cortactin binding protein 2
chr14_-_76956445 2.104 NM_001160326
Serp2
stress-associated endoplasmic reticulum protein family member 2
chr12_+_79327737 2.087 Gphn
gephyrin
chr8_-_74195545 2.082 Unc13a
unc-13 homolog A (C. elegans)
chr4_+_71862277 2.071 C630043F03Rik
RIKEN cDNA C630043F03 gene
chr17_+_27792487 2.062 Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr12_-_77811119 2.037 Spnb1
spectrin beta 1
chr9_-_86775282 2.009 Snap91
synaptosomal-associated protein 91
chr7_+_19867963 2.005 Rtn2
reticulon 2 (Z-band associated protein)
chr16_+_49855691 1.992 NM_010581
Cd47
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr15_-_75397601 1.990 NM_011837
Ly6h
lymphocyte antigen 6 complex, locus H
chr11_+_80290571 1.990 Cdk5r1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr4_+_130348406 1.983 NM_011520
Sdc3
syndecan 3
chr7_+_53040723 1.971 Lmtk3
lemur tyrosine kinase 3
chr12_+_45429857 1.960 NM_001146031
NM_176930
Nrcam

neuron-glia-CAM-related cell adhesion molecule

chr1_-_108610520 1.959 Bcl2
B-cell leukemia/lymphoma 2
chr11_+_98603041 1.956 Thra
thyroid hormone receptor alpha
chr9_+_51573434 1.956 NM_175535
Arhgap20
Rho GTPase activating protein 20
chr4_-_139802683 1.943 NM_198610
Igsf21
immunoglobin superfamily, member 21
chr15_+_30102710 1.942 Ctnnd2
catenin (cadherin associated protein), delta 2
chr12_+_17697623 1.904 Hpcal1
hippocalcin-like 1
chrX_-_61530035 1.897 Slitrk4
SLIT and NTRK-like family, member 4
chr7_-_135561641 1.896 NM_026418
Rgs10
regulator of G-protein signalling 10
chr5_+_37637027 1.895 NM_007765
Crmp1
collapsin response mediator protein 1
chr8_-_74195650 1.892 NM_001029873
Unc13a
unc-13 homolog A (C. elegans)
chr16_+_81200971 1.831 Ncam2
neural cell adhesion molecule 2
chr12_+_79327673 1.828 Gphn
gephyrin
chr4_-_133054355 1.805 NM_001081156
Trnp1
TMF1-regulated nuclear protein 1
chr1_+_59969845 1.800 NM_001037725
Fam117b
family with sequence similarity 117, member B
chr12_+_117724239 1.789 Ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr2_+_144993587 1.787 Slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr6_-_124706435 1.785 NM_007881
Atn1
atrophin 1
chr2_+_90725895 1.777 NM_026161
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr9_-_86775154 1.773 NM_013669
Snap91
synaptosomal-associated protein 91
chr11_+_69154265 1.763 A030009H04Rik
RIKEN cDNA A030009H04 gene
chr5_-_99681835 1.760 NM_145839
NM_181318
Rasgef1b

RasGEF domain family, member 1B

chr12_+_3806955 1.756 NM_007872
Dnmt3a
DNA methyltransferase 3A
chr3_-_143865162 1.748 NM_001161770
NM_001161769
Lmo4

LIM domain only 4

chr2_-_168567422 1.745 Atp9a
ATPase, class II, type 9A
chrX_-_61530170 1.743 NM_178740
Slitrk4
SLIT and NTRK-like family, member 4
chr16_+_16983503 1.739 Mapk1
mitogen-activated protein kinase 1
chr16_-_18629938 1.737 NM_213614
Sept5
septin 5
chr1_+_180459245 1.734 NM_001161665
Kif26b
kinesin family member 26B
chrX_-_152057864 1.727 NM_001093750
Ptchd1
patched domain containing 1
chrX_+_132373572 1.716 NM_001163015
NM_001163016
NM_001163017
Gprasp2


G protein-coupled receptor associated sorting protein 2


chr5_+_117807290 1.714 NM_021539
Wsb2
WD repeat and SOCS box-containing 2
chr17_+_25945986 1.707 NM_001164225
Fbxl16
F-box and leucine-rich repeat protein 16
chr2_-_25174498 1.695 Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr16_+_94592359 1.692 Ttc3
tetratricopeptide repeat domain 3
chr12_+_36883692 1.691 NM_146033
Ankmy2
ankyrin repeat and MYND domain containing 2
chr1_+_75502181 1.674 Obsl1
obscurin-like 1
chr5_-_135554038 1.649 NM_177574
Vps37d
vacuolar protein sorting 37D (yeast)
chr5_-_145522423 1.649 NM_177735
Tmem130
transmembrane protein 130
chr19_+_26679649 1.647 NM_011416
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_179777418 1.636 Ss18l1
synovial sarcoma translocation gene on chromosome 18-like 1
chr8_+_96334452 1.636 NM_001113384
NM_010308
Gnao1

guanine nucleotide binding protein, alpha O

chr14_-_19726121 1.633 NM_144839
Ube2e2
ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr15_-_98126513 1.632 NM_173769
Zfp641
zinc finger protein 641
chr3_+_105255247 1.626 NM_001039347
Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
chr10_-_126971614 1.611 NM_183297
Nxph4
neurexophilin 4
chr10_+_127896244 1.604 NM_001114096
NM_001114097
NM_198160
Smarcc2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2


chr13_-_12199109 1.589 NM_023868
Ryr2
ryanodine receptor 2, cardiac
chr19_+_45005658 1.583 Fam178a
family with sequence similarity 178, member A
chr6_+_22825464 1.580 NM_001081306
Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr3_-_122322556 1.579 NM_001114665
NM_153118
Fnbp1l

formin binding protein 1-like

chr17_+_37187550 1.575 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chrX_+_33735898 1.574 NM_028325
Zcchc12
zinc finger, CCHC domain containing 12
chrX_+_132330678 1.567 Gprasp1
G protein-coupled receptor associated sorting protein 1
chr2_-_25174662 1.567 NM_001177656
NM_001177657
NM_008169
Grin1


glutamate receptor, ionotropic, NMDA1 (zeta 1)


chr11_+_94871620 1.556 Samd14
sterile alpha motif domain containing 14
chr2_+_32006651 1.555 NM_001159634
NM_172661
Prrc2b

proline-rich coiled-coil 2B

chr17_-_64681166 1.554 NM_001025309
NM_144859
Pja2

praja 2, RING-H2 motif containing

chr5_-_21850490 1.549 NM_011261
Reln
reelin
chr6_-_18464792 1.544 NM_080285
Cttnbp2
cortactin binding protein 2
chr9_+_27106773 1.538 NM_001033323
NM_001129787
Igsf9b

immunoglobulin superfamily, member 9B

chr2_-_32568570 1.535 Cdk9
cyclin-dependent kinase 9 (CDC2-related kinase)
chr16_+_94592373 1.535 Ttc3
tetratricopeptide repeat domain 3
chr18_-_61173753 1.518 NM_201353
Slc6a7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr2_-_163744663 1.510 Rims4
regulating synaptic membrane exocytosis 4
chr11_-_35612058 1.509 Fbll1
fibrillarin-like 1
chr11_+_94871181 1.505 NM_146025
Samd14
sterile alpha motif domain containing 14
chr11_-_98190774 1.499 NM_010895
Neurod2
neurogenic differentiation 2
chrX_-_159081510 1.496 NM_178256
Reps2
RALBP1 associated Eps domain containing protein 2
chr11_-_12364886 1.471 NM_172496
Cobl
cordon-bleu
chr7_-_142129892 1.463 NM_001143802
Fam196a
family with sequence similarity 196, member A
chr1_-_164408123 1.457 Dnm3
dynamin 3
chr19_+_10463540 1.450 NM_018801
NM_173067
NM_173068
Syt7


synaptotagmin VII


chr7_-_26460180 1.446 NM_177102
Tmem91
transmembrane protein 91
chr7_-_91558468 1.435 NM_007488
Arnt2
aryl hydrocarbon receptor nuclear translocator 2
chr11_-_95926589 1.427 NM_172300
Ube2z
ubiquitin-conjugating enzyme E2Z (putative)
chr11_+_97660946 1.423 NM_010688
Lasp1
LIM and SH3 protein 1
chr14_-_40286236 1.421 NM_001190187
NM_001190188
NM_008734
Nrg3


neuregulin 3


chr16_+_11984205 1.419 NM_001174086
NM_028277
Shisa9

shisa homolog 9 (Xenopus laevis)

chr9_+_107242932 1.418 NM_175486
6430571L13Rik
RIKEN cDNA 6430571L13 gene
chr13_-_53076251 1.416 NM_017373
Nfil3
nuclear factor, interleukin 3, regulated

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
3.74 3.20e-15 GO:0007399 nervous system development
4.49 2.21e-14 GO:0048699 generation of neurons
4.30 4.89e-14 GO:0022008 neurogenesis
7.04 2.37e-11 GO:0007268 synaptic transmission
5.46 4.89e-11 GO:0007267 cell-cell signaling
6.02 9.69e-11 GO:0019226 transmission of nerve impulse
6.02 9.69e-11 GO:0035637 multicellular organismal signaling
5.92 4.14e-10 GO:0031175 neuron projection development
5.22 4.30e-10 GO:0048666 neuron development
4.43 4.78e-09 GO:0030182 neuron differentiation
4.50 1.62e-08 GO:0030030 cell projection organization
3.87 3.33e-08 GO:0007154 cell communication
2.21 1.31e-07 GO:0048731 system development
5.69 1.74e-07 GO:0045664 regulation of neuron differentiation
6.81 2.02e-07 GO:0050804 regulation of synaptic transmission
10.38 3.93e-07 GO:0006836 neurotransmitter transport
6.32 6.92e-07 GO:0051969 regulation of transmission of nerve impulse
4.95 9.10e-07 GO:0050767 regulation of neurogenesis
4.46 1.23e-06 GO:0044057 regulation of system process
4.63 1.36e-06 GO:0051960 regulation of nervous system development
3.18 1.73e-06 GO:0048468 cell development
4.55 1.86e-06 GO:0007610 behavior
2.04 2.34e-06 GO:0048856 anatomical structure development
5.81 2.65e-06 GO:0031644 regulation of neurological system process
1.96 4.75e-06 GO:0007275 multicellular organismal development
4.30 5.65e-06 GO:0060284 regulation of cell development
1.89 6.99e-06 GO:0032502 developmental process
10.51 7.98e-06 GO:0001505 regulation of neurotransmitter levels
10.38 9.20e-06 GO:0048167 regulation of synaptic plasticity
1.89 1.06e-05 GO:0051179 localization
5.25 1.31e-05 GO:0048812 neuron projection morphogenesis
1.98 2.04e-05 GO:0006810 transport
2.17 3.32e-05 GO:0030154 cell differentiation
1.95 3.95e-05 GO:0051234 establishment of localization
5.19 4.02e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
7.00 5.25e-05 GO:0050890 cognition
5.36 6.59e-05 GO:0007409 axonogenesis
2.10 9.08e-05 GO:0048869 cellular developmental process
1.87 1.43e-04 GO:0016043 cellular component organization
13.21 1.51e-04 GO:0007269 neurotransmitter secretion
9.08 1.64e-04 GO:0030902 hindbrain development
4.35 2.35e-04 GO:0048858 cell projection morphogenesis
4.26 3.15e-04 GO:0032990 cell part morphogenesis
11.86 3.62e-04 GO:0022037 metencephalon development
9.76 3.72e-04 GO:0017157 regulation of exocytosis
2.24 5.54e-04 GO:0051239 regulation of multicellular organismal process
1.79 7.57e-04 GO:0071840 cellular component organization or biogenesis
4.09 1.19e-03 GO:0000904 cell morphogenesis involved in differentiation
6.29 1.67e-03 GO:0007611 learning or memory
16.14 1.69e-03 GO:0021587 cerebellum morphogenesis
11.82 2.06e-03 GO:0048168 regulation of neuronal synaptic plasticity
2.77 2.13e-03 GO:0051049 regulation of transport
3.42 2.19e-03 GO:0007417 central nervous system development
1.93 2.52e-03 GO:0071842 cellular component organization at cellular level
6.66 2.99e-03 GO:0003001 generation of a signal involved in cell-cell signaling
6.66 2.99e-03 GO:0023061 signal release
5.32 3.33e-03 GO:0060627 regulation of vesicle-mediated transport
1.23 3.44e-03 GO:0009987 cellular process
14.06 4.01e-03 GO:0021575 hindbrain morphogenesis
5.13 4.84e-03 GO:0010975 regulation of neuron projection development
2.40 4.88e-03 GO:0032879 regulation of localization
19.11 5.35e-03 GO:0021696 cerebellar cortex morphogenesis
1.99 5.83e-03 GO:0065008 regulation of biological quality
2.53 7.65e-03 GO:0051649 establishment of localization in cell
2.38 8.48e-03 GO:0006796 phosphate metabolic process
2.84 8.50e-03 GO:0007155 cell adhesion
9.59 8.77e-03 GO:0018105 peptidyl-serine phosphorylation
2.37 8.84e-03 GO:0006793 phosphorus metabolic process
1.49 8.98e-03 GO:0032501 multicellular organismal process
2.82 9.74e-03 GO:0022610 biological adhesion
2.10 1.01e-02 GO:0023051 regulation of signaling
2.31 1.07e-02 GO:0010646 regulation of cell communication
2.35 1.09e-02 GO:0051641 cellular localization
1.83 1.14e-02 GO:0071841 cellular component organization or biogenesis at cellular level
15.79 1.48e-02 GO:0018107 peptidyl-threonine phosphorylation
2.66 1.58e-02 GO:0006468 protein phosphorylation
3.03 2.23e-02 GO:0032989 cellular component morphogenesis
4.40 2.27e-02 GO:0031344 regulation of cell projection organization
1.30 2.45e-02 GO:0065007 biological regulation
3.12 2.47e-02 GO:0000902 cell morphogenesis
10.38 2.52e-02 GO:0021549 cerebellum development
8.20 2.52e-02 GO:0070588 calcium ion transmembrane transport
13.97 2.80e-02 GO:0018210 peptidyl-threonine modification
13.97 2.80e-02 GO:0021695 cerebellar cortex development
2.44 3.07e-02 GO:0016310 phosphorylation
3.49 3.37e-02 GO:0046903 secretion
2.37 3.51e-02 GO:2000026 regulation of multicellular organismal development
2.46 3.77e-02 GO:0045595 regulation of cell differentiation
7.70 3.81e-02 GO:0018209 peptidyl-serine modification
1.50 4.32e-02 GO:0023052 signaling
4.11 4.46e-02 GO:0051051 negative regulation of transport
2.87 4.61e-02 GO:0030001 metal ion transport
4.88 4.73e-02 GO:0006813 potassium ion transport
12.52 4.88e-02 GO:0048169 regulation of long-term neuronal synaptic plasticity

Gene overrepresentation in compartment category:

enrichment p-value GO term description
5.89 1.00e-19 GO:0043005 neuron projection
6.40 1.20e-19 GO:0045202 synapse
8.10 7.23e-16 GO:0030424 axon
2.18 4.24e-14 GO:0071944 cell periphery
6.54 7.21e-14 GO:0044456 synapse part
2.18 8.81e-14 GO:0005886 plasma membrane
3.59 1.25e-13 GO:0042995 cell projection
6.88 6.80e-13 GO:0030425 dendrite
5.80 4.38e-11 GO:0044297 cell body
9.90 6.36e-11 GO:0033267 axon part
5.14 1.18e-10 GO:0044463 cell projection part
5.64 6.69e-10 GO:0043025 neuronal cell body
12.10 1.00e-08 GO:0043679 axon terminus
11.24 2.65e-08 GO:0044306 neuron projection terminus
9.54 2.18e-07 GO:0008021 synaptic vesicle
7.00 2.68e-07 GO:0030135 coated vesicle
7.46 3.67e-07 GO:0030136 clathrin-coated vesicle
14.21 2.33e-06 GO:0043195 terminal button
2.62 3.26e-06 GO:0000267 cell fraction
2.85 5.10e-06 GO:0005626 insoluble fraction
12.10 1.02e-05 GO:0030665 clathrin coated vesicle membrane
6.94 1.09e-05 GO:0019717 synaptosome
14.53 1.30e-05 GO:0042734 presynaptic membrane
2.82 1.80e-05 GO:0005624 membrane fraction
2.15 3.06e-05 GO:0044459 plasma membrane part
9.34 1.03e-04 GO:0030662 coated vesicle membrane
1.17 1.46e-04 GO:0005623 cell
1.17 1.46e-04 GO:0044464 cell part
8.96 1.49e-04 GO:0043197 dendritic spine
8.72 1.88e-04 GO:0044309 neuron spine
1.36 4.89e-04 GO:0016020 membrane
15.03 5.01e-04 GO:0030672 synaptic vesicle membrane
36.31 5.06e-04 GO:0061200 clathrin sculpted gamma-aminobutyric acid transport vesicle
36.31 5.06e-04 GO:0061202 clathrin sculpted gamma-aminobutyric acid transport vesicle membrane
32.27 9.00e-04 GO:0060198 clathrin sculpted vesicle
11.47 2.63e-03 GO:0043198 dendritic shaft
2.74 2.83e-03 GO:0030054 cell junction
4.96 3.14e-03 GO:0045211 postsynaptic membrane
2.88 3.27e-03 GO:0031988 membrane-bounded vesicle
7.00 4.01e-03 GO:0014069 postsynaptic density
2.90 4.84e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
20.75 6.77e-03 GO:0032839 dendrite cytoplasm
20.75 6.77e-03 GO:0048786 presynaptic active zone
18.16 1.21e-02 GO:0032838 cell projection cytoplasm
4.63 1.40e-02 GO:0030659 cytoplasmic vesicle membrane
4.49 1.82e-02 GO:0044433 cytoplasmic vesicle part
31.12 1.87e-02 GO:0051233 spindle midzone
2.37 1.90e-02 GO:0031982 vesicle
1.63 2.02e-02 GO:0043234 protein complex
5.59 2.04e-02 GO:0034703 cation channel complex
4.20 3.13e-02 GO:0012506 vesicle membrane
1.32 3.42e-02 GO:0044425 membrane part
13.83 3.75e-02 GO:0034704 calcium channel complex

Gene overrepresentation in function category:

enrichment p-value GO term description
1.85 1.32e-13 GO:0005515 protein binding
1.41 2.26e-10 GO:0005488 binding
7.68 3.74e-06 GO:0005516 calmodulin binding
3.44 3.93e-05 GO:0008092 cytoskeletal protein binding
2.08 1.56e-04 GO:0032555 purine ribonucleotide binding
2.08 1.59e-04 GO:0032553 ribonucleotide binding
2.08 1.76e-04 GO:0017076 purine nucleotide binding
2.00 1.16e-03 GO:0035639 purine ribonucleoside triphosphate binding
3.92 1.90e-03 GO:0022836 gated channel activity
2.08 2.16e-03 GO:0032559 adenyl ribonucleotide binding
1.85 2.39e-03 GO:0000166 nucleotide binding
2.53 2.40e-03 GO:0016301 kinase activity
2.06 2.43e-03 GO:0030554 adenyl nucleotide binding
2.83 7.82e-03 GO:0019904 protein domain specific binding
2.57 8.85e-03 GO:0015075 ion transmembrane transporter activity
3.76 1.18e-02 GO:0005261 cation channel activity
3.76 1.18e-02 GO:0019901 protein kinase binding
3.19 1.22e-02 GO:0005216 ion channel activity
3.12 1.58e-02 GO:0022838 substrate-specific channel activity
1.95 1.74e-02 GO:0005524 ATP binding
3.39 1.87e-02 GO:0019900 kinase binding
2.65 1.95e-02 GO:0004672 protein kinase activity
4.99 2.10e-02 GO:0022843 voltage-gated cation channel activity
3.02 2.29e-02 GO:0015267 channel activity
3.01 2.36e-02 GO:0022803 passive transmembrane transporter activity
10.38 2.74e-02 GO:0019905 syntaxin binding
2.43 2.93e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.73 3.10e-02 GO:0008324 cation transmembrane transporter activity
2.17 3.36e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
2.89 3.87e-02 GO:0004674 protein serine/threonine kinase activity
72.61 4.71e-02 GO:0016534 cyclin-dependent protein kinase 5 activator activity