• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: EHF.p2

Z-value: 2.520

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Top targets:

Promoter	Score	Refseq	Gene	Description
chr4_-_123427465	7.114	NM_023423	Akirin1	akirin 1
chr2_-_5765967	6.490	NM_133837	Cdc123	cell division cycle 123 homolog (S. cerevisiae)
chrX_+_108009728	6.369	NM_008901	Pou3f4	POU domain, class 3, transcription factor 4
chr11_+_86497546	6.077	NM_001098810	Ptrh2	peptidyl-tRNA hydrolase 2
chr2_+_152512797	5.976	NM_025543	Mcts2	malignant T cell amplified sequence 2
chr4_+_131830270	5.713	NM_025579	Taf12	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr6_-_29559792	5.293		Tnpo3	transportin 3
chr1_+_42752608	5.168
chr13_+_12487614	4.954	NM_144835	Heatr1	HEAT repeat containing 1
chr3_-_146184337	4.885	NM_027332 NM_027371	Rpf1	ribosome production factor 1 homolog (S. cerevisiae)
chr9_+_108241599	4.878	NM_008160	Gpx1	glutathione peroxidase 1
chr19_+_5366812	4.852	NM_027236	Eif1ad	eukaryotic translation initiation factor 1A domain containing
chr9_+_14305110	4.688		Cwc15	CWC15 homolog (S. cerevisiae)
chr12_-_66066481	4.675	NM_025707	Klhl28	kelch-like 28 (Drosophila)
chr17_-_37088578	4.651	NM_029632	Ppp1r11	protein phosphatase 1, regulatory (inhibitor) subunit 11
chr7_-_69609363	4.598	NM_013788	Peg12	paternally expressed 12
chr5_-_138596915	4.582	NM_019747	Zfp113	zinc finger protein 113
chr6_-_39370221	4.572		Mkrn1	makorin, ring finger protein, 1
chr19_-_14672540	4.355		Tle4	transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr18_-_84758848	4.346	NM_001033341	Zfp407	zinc finger protein 407
chr2_+_5766274	4.315		Nudt5	nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr8_+_74763920	4.305		Ap1m1	adaptor-related protein complex AP-1, mu subunit 1
chr11_+_70461024	4.215	NM_027445	Rnf167	ring finger protein 167
chr6_-_49164469	4.172		Igf2bp3	insulin-like growth factor 2 mRNA binding protein 3
chr1_+_153191613	4.143	NM_001039511 NM_001039512 NM_054102	Ivns1abp	influenza virus NS1A binding protein
chr5_-_31210054	4.089	NM_001134692	Ost4	oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr19_-_4928237	4.071	NM_133803	Dpp3	dipeptidylpeptidase 3
chr4_+_155205723	3.951	NM_025338	Aurkaip1	aurora kinase A interacting protein 1
chr10_-_22451093	3.936		Tbpl1	TATA box binding protein-like 1
chr14_-_32308152	3.906	NM_025907	Mettl6	methyltransferase like 6
chr7_-_134339388	3.852	NM_027353	Cd2bp2	CD2 antigen (cytoplasmic tail) binding protein 2
chr10_+_127472624	3.811		Naca	nascent polypeptide-associated complex alpha polypeptide
chr11_+_4795308	3.777	NM_172438	Thoc5	THO complex 5
chr11_-_44283916	3.777	NM_024475	Ublcp1	ubiquitin-like domain containing CTD phosphatase 1
chr15_-_75911326	3.771	NM_028364 NM_133691	Puf60	poly-U binding splicing factor 60
chr11_-_58143825	3.771		Gm9900	predicted gene 9900
chr9_+_50412002	3.768	NM_013897	Timm8b	translocase of inner mitochondrial membrane 8 homolog b (yeast)
chr4_+_40895538	3.766	NM_029814	Chmp5	chromatin modifying protein 5
chr16_+_56075576	3.765		Senp7	SUMO1/sentrin specific peptidase 7
chr4_-_59796621	3.750	NM_001013577	1110054O05Rik	RIKEN cDNA 1110054O05 gene
chr9_+_72961223	3.733	NM_198609	Rsl24d1	ribosomal L24 domain containing 1
chr19_-_38893670	3.705	NM_021315	Noc3l	nucleolar complex associated 3 homolog (S. cerevisiae)
chr5_-_86601756	3.655	NM_172712	Uba6	ubiquitin-like modifier activating enzyme 6
chr3_-_27052733	3.635	NM_001177625 NM_007900	Ect2	ect2 oncogene
chr4_+_118081908	3.634	NM_020000 NM_173719	Med8	mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)
chr19_-_14672472	3.614	NM_011600	Tle4	transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr5_+_3803180	3.579		Krit1	KRIT1, ankyrin repeat containing
chr17_-_3557712	3.558	NM_146074	Tfb1m	transcription factor B1, mitochondrial
chr5_-_116474254	3.550	NM_031869	Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr12_+_106923552	3.533	NM_178613	4933433P14Rik	RIKEN cDNA 4933433P14 gene
chr15_-_63829523	3.517		Fam49b	family with sequence similarity 49, member B
chr18_+_35278553	3.508	NM_009818	Ctnna1	catenin (cadherin associated protein), alpha 1
chr4_-_116300068	3.465	NM_001081475	Nasp	nuclear autoantigenic sperm protein (histone-binding)
chr12_+_66066728	3.425	NM_177805	Fam179b	family with sequence similarity 179, member B
chrX_-_9793824	3.411	NM_001177950 NM_001177951 NM_001177953 NM_001177954 NM_011285	Rpgr	retinitis pigmentosa GTPase regulator
chr16_+_31948631	3.408	NM_026554	Ncbp2	nuclear cap binding protein subunit 2
chr14_-_19164241	3.364	NM_009455	Ube2e1	ubiquitin-conjugating enzyme E2E 1, UBC4/5 homolog (yeast)
chr7_+_133630844	3.341	NM_001163713 NM_172745	Tufm	Tu translation elongation factor, mitochondrial
chr1_-_34496128	3.279		Ccdc115	coiled-coil domain containing 115
chr5_+_149996135	3.222	NM_001013378 NM_001115149 NM_001115150 NM_001115151 NM_001115153	Uspl1	ubiquitin specific peptidase like 1
chr6_+_35202672	3.210		1810058I24Rik	RIKEN cDNA 1810058I24 gene
chr11_-_35793951	3.203		Wwc1	WW, C2 and coiled-coil domain containing 1
chr5_-_9161670	3.193	NM_001110327 NM_011806	Dmtf1	cyclin D binding myb-like transcription factor 1
chr14_-_70553471	3.171		2610301G19Rik	RIKEN cDNA 2610301G19 gene
chr8_-_72519966	3.135	NM_001113345 NM_145596	Gatad2a	GATA zinc finger domain containing 2A
chr10_-_92185071	3.130	NM_008682	Nedd1	neural precursor cell expressed, developmentally down-regulated gene 1
chr3_+_102799658	3.123	NM_025679	Sike1	suppressor of IKBKE 1
chr3_+_87734217	3.092	NM_177663	Isg20l2	interferon stimulated exonuclease gene 20-like 2
chr6_+_34304098	3.091	NM_008012	Akr1b8	aldo-keto reductase family 1, member B8
chr14_+_21493519	3.089	NM_001168273 NM_172596	Sec24c	Sec24 related gene family, member C (S. cerevisiae)
chr2_-_38499436	3.079		Psmb7	proteasome (prosome, macropain) subunit, beta type 7
chr4_+_41082861	3.068		Ube2r2	ubiquitin-conjugating enzyme E2R 2
chr11_+_43247252	3.060		Slu7	SLU7 splicing factor homolog (S. cerevisiae)
chr11_-_104411728	3.037	NM_145436	Cdc27	cell division cycle 27 homolog (S. cerevisiae)
chr17_-_46384918	3.005	NM_009085	Polr1c	polymerase (RNA) I polypeptide C
chr7_+_140829357	3.005	NM_178115	2700050L05Rik	RIKEN cDNA 2700050L05 gene
chr12_+_21292157	3.003	NM_018813	Cpsf3	cleavage and polyadenylation specificity factor 3
chr1_+_120285920	2.983		Clasp1	CLIP associating protein 1
chr2_+_38860784	2.958		Wdr38	WD repeat domain 38
chr17_-_86544514	2.955	NM_030133	Srbd1	S1 RNA binding domain 1
chr5_-_5514787	2.955	NM_001193660 NM_001193659 NM_001193661 NM_022890	Cldn12	claudin 12
chr3_-_107948968	2.950		Gnai3	guanine nucleotide binding protein (G protein), alpha inhibiting 3
chr13_+_120251565	2.937	NM_001113550 NM_026127	4833420G17Rik	RIKEN cDNA 4833420G17 gene
chr9_-_20325813	2.910	NM_001082485 NM_001135019	Zfp266	zinc finger protein 266
chr2_-_38860622	2.903	NM_025592	Rpl35	ribosomal protein L35
chr10_-_117229719	2.897	NM_134010	Nup107	nucleoporin 107
chr1_+_122499031	2.887	NM_010133	En1	engrailed 1
chr19_-_8848911	2.883	NM_026325	Tmem179b	transmembrane protein 179B
chr1_-_135506798	2.844	NM_009227	Snrpe	small nuclear ribonucleoprotein E
chr14_+_49686169	2.841	NM_144535	Mudeng	MU-2/AP1M2 domain containing, death-inducing
chr13_+_69948718	2.829	NM_138596	Med10	mediator of RNA polymerase II transcription, subunit 10 homolog (NUT2, S. cerevisiae)
chr14_-_52816830	2.829	NM_033618	Supt16h	suppressor of Ty 16 homolog (S. cerevisiae)
chr17_-_28046158	2.819		Taf11	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr4_+_118293403	2.807	NM_026932	Ebna1bp2	EBNA1 binding protein 2
chr5_+_21292545	2.797		Psmc2	proteasome (prosome, macropain) 26S subunit, ATPase 2
chr9_-_114690887	2.792	NM_133978	Cmtm7	CKLF-like MARVEL transmembrane domain containing 7
chr11_-_66866062	2.789		2310004I24Rik	RIKEN cDNA 2310004I24 gene
chr12_+_8214912	2.778	NM_172401 NM_001167768 NM_001167767	1110057K04Rik	RIKEN cDNA 1110057K04 gene
chr16_+_10412017	2.770	NM_011955	Nubp1	nucleotide binding protein 1
chr7_-_11080687	2.767	NM_009577	Zik1	zinc finger protein interacting with K protein 1
chr11_+_87881747	2.758	NM_016686	Vezf1	vascular endothelial zinc finger 1
chr7_+_16760712	2.748	NM_008627	Meis3	Meis homeobox 3
chr11_+_120645560	2.746	NM_001177874	Gps1	G protein pathway suppressor 1
chr6_-_116578970	2.731	NM_026057	Zfp422	zinc finger protein 422
chr17_+_35272395	2.722		Bag6	BCL2-associated athanogene 6
chr11_-_100389160	2.707		Acly	ATP citrate lyase
chr9_+_98464116	2.696	NM_015827	Copb2	coatomer protein complex, subunit beta 2 (beta prime)
chr12_+_56499761	2.694	NM_011968	Psma6	proteasome (prosome, macropain) subunit, alpha type 6
chr4_-_45333366	2.683	NM_025513	Exosc3	exosome component 3
chr2_+_115407409	2.676	NM_001145898 NM_207264	BC052040	cDNA sequence BC052040
chr19_+_6363686	2.664	NM_001110791 NM_011750	Sf1	splicing factor 1
chr2_+_120996896	2.662	NM_153387	Tubgcp4	tubulin, gamma complex associated protein 4
chr10_-_39966784	2.660	NM_001042556 NM_023323	Rpf2	ribosome production factor 2 homolog (S. cerevisiae)
chr4_-_46151281	2.659	NM_173033	Tstd2	thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr2_+_122564227	2.639	NM_019788	Pldn	pallidin
chr3_-_107949028	2.620	NM_010306	Gnai3	guanine nucleotide binding protein (G protein), alpha inhibiting 3
chr2_-_37298623	2.617	NM_199025	Zbtb26	zinc finger and BTB domain containing 26
chr11_-_70468019	2.605		Pfn1	profilin 1
chr5_+_145901253	2.586	NM_001008705	Bud31	BUD31 homolog (yeast)
chrX_-_12339096	2.577	NM_001048208 NM_012005	Med14	mediator complex subunit 14
chr10_+_94977721	2.544	NM_080560	Ube2n	ubiquitin-conjugating enzyme E2N
chr16_-_38522680	2.541	NM_024273	4930455C21Rik	RIKEN cDNA 4930455C21 gene
chr4_+_133140278	2.531	NM_133884	Gpn2	GPN-loop GTPase 2
chr2_+_128955435	2.515	NM_025395	Chchd5	coiled-coil-helix-coiled-coil-helix domain containing 5
chr9_+_50412050	2.514		Timm8b	translocase of inner mitochondrial membrane 8 homolog b (yeast)
chr15_+_102034075	2.482		Zfp740	zinc finger protein 740
chr19_+_10969876	2.466		Prpf19	PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
chr17_+_13109289	2.463	NM_013686	Tcp1	t-complex protein 1
chr2_+_14976877	2.460	NM_029466	Arl5b	ADP-ribosylation factor-like 5B
chr5_+_138558132	2.451	NM_001044703 NM_001044704 NM_001044705 NM_011757	Zscan21	zinc finger and SCAN domain containing 21
chr7_+_13551155	2.446		Zfp324	zinc finger protein 324
chr15_-_77801154	2.428	NM_018749	Eif3d	eukaryotic translation initiation factor 3, subunit D
chr7_-_54175214	2.417	NM_021884	Tsg101	tumor susceptibility gene 101
chr9_+_18096674	2.405	NM_025844	Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr2_+_90519527	2.397		Nup160	nucleoporin 160
chr1_+_74648028	2.393	NM_175031	Stk36	serine/threonine kinase 36 (fused homolog, Drosophila)
chr3_+_116297899	2.390	NM_028349	Sass6	spindle assembly 6 homolog (C. elegans)
chr2_+_90744878	2.387	NM_025991	Kbtbd4	kelch repeat and BTB (POZ) domain containing 4
chr7_-_125999115	2.384	NM_001168220	2310008H09Rik	RIKEN cDNA 2310008H09 gene
chr19_+_9016335	2.373	NM_011842	Mta2	metastasis-associated gene family, member 2
chr2_-_114001033	2.356	NM_009702	Aqr	aquarius
chr11_-_66866101	2.347	NM_025510	2310004I24Rik	RIKEN cDNA 2310004I24 gene
chr6_+_142294174	2.345	NM_183165	Pyroxd1	pyridine nucleotide-disulphide oxidoreductase domain 1
chr2_+_90780665	2.345		Celf1	CUGBP, Elav-like family member 1
chrX_+_45976916	2.338		Slc25a14	solute carrier family 25 (mitochondrial carrier, brain), member 14
chr16_-_17928270	2.336	NM_153150	Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chr15_-_54903657	2.334	NM_001081288	Taf2	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr8_+_112302530	2.332	NM_009677	Ap1g1	adaptor protein complex AP-1, gamma 1 subunit
chrX_+_7419025	2.327		Otud5	OTU domain containing 5
chr4_+_11413062	2.327	NM_001081183	1110037F02Rik	RIKEN cDNA 1110037F02 gene
chr16_-_17111300	2.326	NM_144954	Ppil2	peptidylprolyl isomerase (cyclophilin)-like 2
chr13_-_55463928	2.325		Lman2	lectin, mannose-binding 2
chrX_+_35542969	2.306	NM_001079513 NM_020256	Zbtb33	zinc finger and BTB domain containing 33
chr1_-_173177232	2.275		Ndufs2	NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr1_+_89110472	2.267	NM_001039170 NM_023314 NM_001039169	Eif4e2	eukaryotic translation initiation factor 4E member 2
chr19_-_7457315	2.262		AI846148	expressed sequence AI846148
chr5_+_21151760	2.262	NM_026034	Armc10	armadillo repeat containing 10
chr7_-_31758185	2.251		Lsr	lipolysis stimulated lipoprotein receptor
chr14_+_56291071	2.247	NM_177992	Gmpr2	guanosine monophosphate reductase 2
chr1_+_63223396	2.245	NM_018796	Eef1b2	eukaryotic translation elongation factor 1 beta 2
chr6_-_29559606	2.230	NM_177296	Tnpo3	transportin 3
chr17_-_29144679	2.227	NM_134115	Stk38	serine/threonine kinase 38
chr17_-_71199129	2.226	NM_001164076	Tgif1	TGFB-induced factor homeobox 1
chr18_+_35278585	2.222		Ctnna1	catenin (cadherin associated protein), alpha 1
chr2_+_28980511	2.222	NM_198033	Setx	senataxin
chr17_-_15963372	2.215	NM_178615	Rgmb	RGM domain family, member B
chr14_+_47896669	2.213	NM_080843	Socs4	suppressor of cytokine signaling 4
chr7_-_133935952	2.212	NM_019674	Ppp4c	protein phosphatase 4, catalytic subunit
chr6_+_88415396	2.210	NM_019685	Ruvbl1	RuvB-like protein 1
chr11_-_72028494	2.209		Med31	mediator of RNA polymerase II transcription, subunit 31 homolog (yeast)
chr4_+_46151601	2.208		Ncbp1	nuclear cap binding protein subunit 1
chr11_+_98219742	2.207		Stard3	START domain containing 3
chr8_-_113370626	2.206	NM_133953	Sf3b3	splicing factor 3b, subunit 3
chr13_-_45097365	2.205	NM_025772	Dtnbp1	dystrobrevin binding protein 1
chr1_-_173177238	2.204		Ndufs2	NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr13_-_8995234	2.202	NM_027000	Gtpbp4	GTP binding protein 4
chr16_+_58408609	2.194	NM_028523	Dcbld2	discoidin, CUB and LCCL domain containing 2
chr2_+_74663857	2.184	NM_016804	Mtx2	metaxin 2
chr7_-_137409721	2.183		Fgfr2	fibroblast growth factor receptor 2
chr7_-_51809255	2.181	NM_009473	Nr1h2	nuclear receptor subfamily 1, group H, member 2
chr16_+_19760300	2.172	NM_001159407 NM_001159408 NM_054052	B3gnt5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chrX_+_102275071	2.172	NM_026312	2610029G23Rik	RIKEN cDNA 2610029G23 gene
chr5_-_31829057	2.160		Supt7l	suppressor of Ty 7 (S. cerevisiae)-like
chr15_+_99803329	2.158		Larp4	La ribonucleoprotein domain family, member 4
chr19_-_43827386	2.151	NM_144874	Cox15	COX15 homolog, cytochrome c oxidase assembly protein (yeast)
chr11_-_100389196	2.147	NM_134037	Acly	ATP citrate lyase
chr8_-_85856284	2.132	NM_001170691 NM_178736	Elmod2	ELMO domain containing 2
chr19_-_10651550	2.130	NM_028411	Tmem138	transmembrane protein 138
chr2_+_148498350	2.122	NM_019761 NM_001110159	Nxt1	NTF2-related export protein 1
chr17_+_47730384	2.117	NM_007632	Ccnd3	cyclin D3
chr12_+_87423503	2.109	NM_029601	1700019E19Rik	RIKEN cDNA 1700019E19 gene
chr6_-_91361356	2.108	NM_009527	Wnt7a	wingless-related MMTV integration site 7A
chr12_+_86311859	2.103	NM_028632	Fcf1	FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)
chr6_+_86321479	2.090	NM_026506	Snrpg	small nuclear ribonucleoprotein polypeptide G
chr2_+_48669677	2.089		Acvr2a	activin receptor IIA
chr6_+_64992810	2.081		Smarcad1	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr4_-_135528494	2.076	NM_011942	Lypla2	lysophospholipase 2
chr16_+_13780778	2.076	NM_001039521	Rrn3	RRN3 RNA polymerase I transcription factor homolog (yeast)
chr9_+_122832164	2.065	NM_009544	Zfp105	zinc finger protein 105
chr15_-_79604806	2.059	NM_017470	Dnalc4	dynein, axonemal, light chain 4

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.03	1.85e-38	GO:0044260	cellular macromolecule metabolic process
1.89	5.59e-34	GO:0043170	macromolecule metabolic process
1.68	9.19e-27	GO:0044237	cellular metabolic process
2.30	9.32e-27	GO:0010467	gene expression
1.65	2.94e-25	GO:0044238	primary metabolic process
2.14	3.03e-22	GO:0090304	nucleic acid metabolic process
1.51	1.69e-19	GO:0008152	metabolic process
1.94	3.22e-19	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.15	5.98e-19	GO:0016070	RNA metabolic process
2.11	1.93e-16	GO:0044267	cellular protein metabolic process
3.64	3.28e-16	GO:0006396	RNA processing
1.79	6.50e-16	GO:0006807	nitrogen compound metabolic process
1.79	1.60e-15	GO:0034641	cellular nitrogen compound metabolic process
5.82	3.42e-15	GO:0022613	ribonucleoprotein complex biogenesis
4.79	5.57e-15	GO:0008380	RNA splicing
5.52	2.17e-14	GO:0071843	cellular component biogenesis at cellular level
1.95	1.40e-13	GO:0009059	macromolecule biosynthetic process
1.96	1.55e-13	GO:0034645	cellular macromolecule biosynthetic process
1.86	1.90e-12	GO:0019538	protein metabolic process
4.24	6.30e-12	GO:0006397	mRNA processing
3.82	1.45e-11	GO:0016071	mRNA metabolic process
4.26	2.50e-11	GO:0006511	ubiquitin-dependent protein catabolic process
4.17	5.28e-11	GO:0019941	modification-dependent protein catabolic process
4.14	6.74e-11	GO:0043632	modification-dependent macromolecule catabolic process
4.03	1.55e-10	GO:0051603	proteolysis involved in cellular protein catabolic process
1.88	1.86e-10	GO:0071841	cellular component organization or biogenesis at cellular level
3.96	2.77e-10	GO:0044257	cellular protein catabolic process
3.77	6.86e-10	GO:0030163	protein catabolic process
3.88	2.18e-09	GO:0006412	translation
3.25	2.80e-09	GO:0044265	cellular macromolecule catabolic process
5.43	1.55e-08	GO:0042254	ribosome biogenesis
1.65	2.91e-08	GO:0044249	cellular biosynthetic process
5.03	3.36e-08	GO:0010498	proteasomal protein catabolic process
5.03	3.36e-08	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
1.63	4.53e-08	GO:0009058	biosynthetic process
2.90	9.17e-08	GO:0009057	macromolecule catabolic process
7.24	1.36e-07	GO:0022618	ribonucleoprotein complex assembly
7.03	2.24e-07	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
6.51	2.54e-07	GO:0051443	positive regulation of ubiquitin-protein ligase activity
1.98	2.84e-07	GO:0006996	organelle organization
6.93	2.85e-07	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
6.83	3.61e-07	GO:0071826	ribonucleoprotein complex subunit organization
6.35	3.92e-07	GO:0051351	positive regulation of ligase activity
1.56	4.78e-07	GO:0060255	regulation of macromolecule metabolic process
6.47	8.96e-07	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
6.91	1.01e-06	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.04	1.03e-06	GO:0000278	mitotic cell cycle
1.60	1.13e-06	GO:0071840	cellular component organization or biogenesis
2.31	1.54e-06	GO:0007049	cell cycle
5.73	2.37e-06	GO:0051438	regulation of ubiquitin-protein ligase activity
6.52	2.54e-06	GO:0051352	negative regulation of ligase activity
6.52	2.54e-06	GO:0051444	negative regulation of ubiquitin-protein ligase activity
1.72	2.73e-06	GO:0071842	cellular component organization at cellular level
5.60	3.42e-06	GO:0051340	regulation of ligase activity
1.62	3.67e-06	GO:0010468	regulation of gene expression
5.59	9.76e-06	GO:0031397	negative regulation of protein ubiquitination
3.11	1.13e-05	GO:0070647	protein modification by small protein conjugation or removal
4.91	1.23e-05	GO:0031398	positive regulation of protein ubiquitination
5.29	2.34e-05	GO:0006364	rRNA processing
1.76	2.38e-05	GO:0006351	transcription, DNA-dependent
1.76	2.61e-05	GO:0032774	RNA biosynthetic process
5.13	3.84e-05	GO:0016072	rRNA metabolic process
1.44	4.91e-05	GO:0019222	regulation of metabolic process
2.40	5.67e-05	GO:0022402	cell cycle process
1.47	5.72e-05	GO:0031323	regulation of cellular metabolic process
1.48	5.81e-05	GO:0080090	regulation of primary metabolic process
3.33	6.50e-05	GO:0016567	protein ubiquitination
5.96	8.92e-05	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
5.96	8.92e-05	GO:0000398	nuclear mRNA splicing, via spliceosome
7.96	9.65e-05	GO:0006413	translational initiation
2.90	9.82e-05	GO:0016568	chromatin modification
1.17	1.04e-04	GO:0009987	cellular process
3.17	1.06e-04	GO:0032446	protein modification by small protein conjugation
5.87	1.08e-04	GO:0000375	RNA splicing, via transesterification reactions
3.91	2.58e-04	GO:0031396	regulation of protein ubiquitination
1.57	3.45e-04	GO:0051252	regulation of RNA metabolic process
1.55	4.17e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.61	7.38e-04	GO:0006325	chromatin organization
1.91	1.09e-03	GO:0044085	cellular component biogenesis
1.55	1.14e-03	GO:0006355	regulation of transcription, DNA-dependent
1.48	1.56e-03	GO:0016043	cellular component organization
1.51	1.58e-03	GO:0010556	regulation of macromolecule biosynthetic process
2.65	1.79e-03	GO:0051301	cell division
2.04	2.83e-03	GO:0006508	proteolysis
2.93	5.65e-03	GO:0034660	ncRNA metabolic process
3.31	6.61e-03	GO:0031400	negative regulation of protein modification process
1.58	1.35e-02	GO:0043412	macromolecule modification
2.17	1.63e-02	GO:0051276	chromosome organization
1.44	1.64e-02	GO:0031326	regulation of cellular biosynthetic process
1.43	1.90e-02	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.31	1.93e-02	GO:0006974	response to DNA damage stimulus
1.59	1.95e-02	GO:0006464	protein modification process
3.04	2.31e-02	GO:0034470	ncRNA processing
2.69	2.43e-02	GO:0032269	negative regulation of cellular protein metabolic process
2.55	2.60e-02	GO:0006281	DNA repair
19.30	2.71e-02	GO:0009452	RNA capping
2.15	2.73e-02	GO:0006259	DNA metabolic process
1.42	3.01e-02	GO:0009889	regulation of biosynthetic process
1.42	3.11e-02	GO:0051171	regulation of nitrogen compound metabolic process
2.47	3.12e-02	GO:0034621	cellular macromolecular complex subunit organization
2.57	3.24e-02	GO:0034622	cellular macromolecular complex assembly
2.00	3.52e-02	GO:0046907	intracellular transport
2.57	4.83e-02	GO:0051248	negative regulation of protein metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.03	3.01e-43	GO:0005634	nucleus
1.49	1.45e-39	GO:0044424	intracellular part
1.47	2.86e-38	GO:0005622	intracellular
1.54	6.96e-35	GO:0043229	intracellular organelle
1.54	1.64e-34	GO:0043226	organelle
1.60	2.08e-34	GO:0043231	intracellular membrane-bounded organelle
1.60	3.65e-34	GO:0043227	membrane-bounded organelle
2.65	5.58e-28	GO:0044428	nuclear part
2.40	3.25e-19	GO:0070013	intracellular organelle lumen
2.39	3.84e-19	GO:0043233	organelle lumen
2.36	8.24e-19	GO:0031974	membrane-enclosed lumen
2.49	2.08e-18	GO:0031981	nuclear lumen
1.88	2.51e-18	GO:0032991	macromolecular complex
1.72	1.64e-16	GO:0044446	intracellular organelle part
1.69	1.86e-15	GO:0044422	organelle part
2.43	2.90e-11	GO:0005654	nucleoplasm
1.77	3.48e-11	GO:0043234	protein complex
3.01	2.92e-09	GO:0030529	ribonucleoprotein complex
6.87	5.64e-09	GO:0071013	catalytic step 2 spliceosome
4.97	5.26e-08	GO:0005681	spliceosomal complex
1.30	9.98e-08	GO:0005737	cytoplasm
7.36	2.63e-07	GO:0000502	proteasome complex
2.27	1.25e-05	GO:0044451	nucleoplasm part
1.12	3.48e-05	GO:0005623	cell
1.12	3.48e-05	GO:0044464	cell part
4.21	3.12e-04	GO:0000151	ubiquitin ligase complex
1.68	5.90e-04	GO:0005829	cytosol
13.36	6.16e-04	GO:0005852	eukaryotic translation initiation factor 3 complex
2.45	1.18e-03	GO:0005730	nucleolus
1.49	1.61e-03	GO:0043228	non-membrane-bounded organelle
1.49	1.61e-03	GO:0043232	intracellular non-membrane-bounded organelle
12.86	4.12e-02	GO:0031080	Nup107-160 complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
3.03	1.07e-14	GO:0003723	RNA binding
1.90	4.91e-14	GO:0003676	nucleic acid binding
7.36	3.13e-07	GO:0003743	translation initiation factor activity
5.60	7.98e-07	GO:0008135	translation factor activity, nucleic acid binding
1.19	1.89e-05	GO:0005488	binding
2.49	3.57e-04	GO:0016874	ligase activity
1.51	2.62e-03	GO:0000166	nucleotide binding
3.01	6.31e-03	GO:0004842	ubiquitin-protein ligase activity
2.79	1.75e-02	GO:0019787	small conjugating protein ligase activity
7.89	2.44e-02	GO:0046966	thyroid hormone receptor binding
2.60	3.12e-02	GO:0016881	acid-amino acid ligase activity
7.55	3.20e-02	GO:0016455	RNA polymerase II transcription mediator activity