Motif ID: ELF1,2,4.p2

Z-value: 2.876

Transcription factors associated with ELF1,2,4.p2:

NameEntrezDescription
Elf1 13709 E74-like factor 1
Elf2 69257 E74-like factor 2
Elf4 56501 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Elf2chr3_-_511444700.841.1e-10Click!
Elf4chrX_-_458073390.572.8e-04Click!
Elf1chr14_+_798809520.511.6e-03Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr8_-_73183546 11.803 Pgpep1
pyroglutamyl-peptidase I
chr2_+_5766274 9.004 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr4_+_154335029 8.850 NM_010419
Hes5
hairy and enhancer of split 5 (Drosophila)
chr4_-_123427465 8.128 NM_023423
Akirin1
akirin 1
chr8_-_73183574 7.967 NM_023217
Pgpep1
pyroglutamyl-peptidase I
chr2_-_23011403 7.185 NM_025979
Mastl
microtubule associated serine/threonine kinase-like
chr19_+_10969876 6.992 Prpf19
PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
chr16_+_48994292 6.932 NM_172616
C330027C09Rik
RIKEN cDNA C330027C09 gene
chr11_-_74992301 6.827 NM_027136
Ovca2
candidate tumor suppressor in ovarian cancer 2
chr6_+_117856781 6.679 NM_001166430
NM_001166431
NM_133834
Hnrnpf


heterogeneous nuclear ribonucleoprotein F


chr3_+_135101248 6.664 Ube2d3
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr15_-_10644312 6.554 NM_001166408
Rai14
retinoic acid induced 14
chr6_+_117867280 6.419 NM_001166427
Hnrnpf
heterogeneous nuclear ribonucleoprotein F
chr19_+_4192077 6.336 NM_031868
Ppp1ca
protein phosphatase 1, catalytic subunit, alpha isoform
chr4_+_46151361 6.307 NM_001033201
Ncbp1
nuclear cap binding protein subunit 1
chr5_-_30399962 6.046 NM_021288
Tyms
thymidylate synthase
chr4_+_131830270 6.044 NM_025579
Taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr18_+_35278553 6.044 NM_009818
Ctnna1
catenin (cadherin associated protein), alpha 1
chr2_+_70893791 6.042 NM_001165980
NM_001165981
NM_001165982
NM_198005
Dcaf17



DDB1 and CUL4 associated factor 17



chr8_-_72519966 5.987 NM_001113345
NM_145596
Gatad2a

GATA zinc finger domain containing 2A

chr6_+_83087016 5.900 NM_009106
NM_133641
Rtkn

rhotekin

chr4_+_41082861 5.801 Ube2r2
ubiquitin-conjugating enzyme E2R 2
chr2_+_156665812 5.768 NM_173396
Tgif2
TGFB-induced factor homeobox 2
chr15_-_103045710 5.758 NM_001110216
NM_007626
Cbx5

chromobox homolog 5 (Drosophila HP1a)

chr2_-_5765967 5.751 NM_133837
Cdc123
cell division cycle 123 homolog (S. cerevisiae)
chr6_-_124662155 5.748 NM_013536
Emg1
EMG1 nucleolar protein homolog (S. cerevisiae)
chr4_-_45333366 5.691 NM_025513
Exosc3
exosome component 3
chr18_+_35278538 5.622 Ctnna1
catenin (cadherin associated protein), alpha 1
chr3_-_157694667 5.456 NM_001093753
Srsf11
serine/arginine-rich splicing factor 11
chrX_-_90877453 5.408 NM_008892
Pola1
polymerase (DNA directed), alpha 1
chr2_+_14976877 5.217 NM_029466
Arl5b
ADP-ribosylation factor-like 5B
chr6_-_116578970 5.184 NM_026057
Zfp422
zinc finger protein 422
chr2_-_126501173 5.145 NM_010249
NM_207669
Gabpb1

GA repeat binding protein, beta 1

chr1_-_173957316 5.040 NM_033509
Vangl2
vang-like 2 (van gogh, Drosophila)
chr3_-_84386546 4.985 NM_001081093
Arfip1
ADP-ribosylation factor interacting protein 1
chr5_+_34678976 4.961 NM_011278
Rnf4
ring finger protein 4
chr17_-_71351465 4.947 2900073G15Rik
RIKEN cDNA 2900073G15 gene
chr1_-_93309713 4.896 NM_019479
Hes6
hairy and enhancer of split 6 (Drosophila)
chr6_+_120314442 4.855 Kdm5a
lysine (K)-specific demethylase 5A
chr3_-_58329639 4.843 Serp1
stress-associated endoplasmic reticulum protein 1
chr5_-_3647805 4.772 NM_026033
Gatad1
GATA zinc finger domain containing 1
chr17_-_71351523 4.702 2900073G15Rik
RIKEN cDNA 2900073G15 gene
chr16_+_14705932 4.686 NM_011415
Snai2
snail homolog 2 (Drosophila)
chr18_+_70727897 4.656 NM_010773
Mbd2
methyl-CpG binding domain protein 2
chr12_+_86114195 4.651 NM_028863
Isca2
iron-sulfur cluster assembly 2 homolog (S. cerevisiae)
chr19_+_38129500 4.625 NM_028293
NM_001164362
NM_028760
Cep55


centrosomal protein 55


chr11_+_86497546 4.608 NM_001098810
Ptrh2
peptidyl-tRNA hydrolase 2
chr1_+_174306656 4.586 NM_026234
Pigm
phosphatidylinositol glycan anchor biosynthesis, class M
chr19_-_58529766 4.573 Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr13_+_41096358 4.526 NM_026550
Pak1ip1
PAK1 interacting protein 1
chr4_+_153385839 4.471 NM_201226
Lrrc47
leucine rich repeat containing 47
chr5_+_46061125 4.470 NM_019438
Ncapg
non-SMC condensin I complex, subunit G
chr16_-_38522680 4.418 NM_024273
4930455C21Rik
RIKEN cDNA 4930455C21 gene
chr13_-_55463928 4.415 Lman2
lectin, mannose-binding 2
chr10_-_79896330 4.407 Tcf3
transcription factor 3
chr11_-_94515034 4.365 Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr15_-_64214427 4.312 NM_010026
Asap1
ArfGAP with SH# domain, ankyrin repeat and PH domain1
chr19_-_46119635 4.298 NM_001113408
Ldb1
LIM domain binding 1
chr18_+_60934249 4.296 NM_020600
Rps14
ribosomal protein S14
chr8_+_86479405 4.269 NM_024184
Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr3_+_87734217 4.229 NM_177663
Isg20l2
interferon stimulated exonuclease gene 20-like 2
chr2_+_152512797 4.227 NM_025543
Mcts2
malignant T cell amplified sequence 2
chr15_-_75911326 4.207 NM_028364
NM_133691
Puf60

poly-U binding splicing factor 60

chr5_+_124566075 4.183 NM_144509
Arl6ip4
ADP-ribosylation factor-like 6 interacting protein 4
chr11_-_97490978 4.158 NM_175332
E130012A19Rik
RIKEN cDNA E130012A19 gene
chr4_-_118109775 4.149 NM_023223
Cdc20
cell division cycle 20 homolog (S. cerevisiae)
chr10_-_87609629 4.108 NM_029249
4930547N16Rik
RIKEN cDNA 4930547N16 gene
chr19_-_4928237 4.095 NM_133803
Dpp3
dipeptidylpeptidase 3
chr11_-_100956699 4.094 NM_008949
Psmc3ip
proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
chr5_+_135663096 4.081 NM_011714
Baz1b
bromodomain adjacent to zinc finger domain, 1B
chr17_-_87424652 4.080 NM_008838
Pigf
phosphatidylinositol glycan anchor biosynthesis, class F
chr19_-_10278231 4.077 NM_007999
Fen1
flap structure specific endonuclease 1
chr14_+_33015123 4.056 NM_011960
Parg
poly (ADP-ribose) glycohydrolase
chr17_-_86544514 4.027 NM_030133
Srbd1
S1 RNA binding domain 1
chr19_+_5366812 4.005 NM_027236
Eif1ad
eukaryotic translation initiation factor 1A domain containing
chr15_+_10415766 3.995 NM_011232
Rad1
RAD1 homolog (S. pombe)
chr5_+_53981453 3.962 NM_009035
NM_001080927
Rbpj

recombination signal binding protein for immunoglobulin kappa J region

chr4_+_118293403 3.962 NM_026932
Ebna1bp2
EBNA1 binding protein 2
chr3_+_88425073 3.945 Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr4_+_41082993 3.918 NM_026275
Ube2r2
ubiquitin-conjugating enzyme E2R 2
chr6_-_87788670 3.905 Isy1
ISY1 splicing factor homolog (S. cerevisiae)
chr13_-_101545800 3.867 NM_021886
Cenph
centromere protein H
chr18_+_54021746 3.863 NM_152809
Csnk1g3
casein kinase 1, gamma 3
chr4_+_124392019 3.844 NM_029157
Sf3a3
splicing factor 3a, subunit 3
chr6_+_133985988 3.832 Etv6
ets variant gene 6 (TEL oncogene)
chr7_-_5013650 3.832 Ccdc106
coiled-coil domain containing 106
chr10_-_117147722 3.810 Mdm2
transformed mouse 3T3 cell double minute 2
chr7_+_5013744 3.792 NM_133671
U2af2
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
chr19_-_7416286 3.771 NM_001080388
NM_001080389
NM_007928
Mark2


MAP/microtubule affinity-regulating kinase 2


chr3_+_14578670 3.762 NM_007892
E2f5
E2F transcription factor 5
chr9_+_122832164 3.748 NM_009544
Zfp105
zinc finger protein 105
chr4_-_107596123 3.731 NM_009949
Cpt2
carnitine palmitoyltransferase 2
chr19_-_41338400 3.715 NM_133352
Tm9sf3
transmembrane 9 superfamily member 3
chr3_+_79395280 3.705 NM_026352
Ppid
peptidylprolyl isomerase D (cyclophilin D)
chr2_+_181498036 3.694 NM_001171615
Myt1
myelin transcription factor 1
chr18_+_46757333 3.687 NM_010120
Eif1a
eukaryotic translation initiation factor 1A
chr1_+_154613763 3.676 Arpc5
actin related protein 2/3 complex, subunit 5
chr2_+_90780665 3.667 Celf1
CUGBP, Elav-like family member 1
chr11_-_70468061 3.657 Pfn1
profilin 1
chr13_+_69948718 3.655 NM_138596
Med10
mediator of RNA polymerase II transcription, subunit 10 homolog (NUT2, S. cerevisiae)
chr15_-_97923632 3.646 NM_144851
Senp1
SUMO1/sentrin specific peptidase 1
chr9_+_108241599 3.645 NM_008160
Gpx1
glutathione peroxidase 1
chr1_+_84836413 3.644 NM_025386
Fbxo36
F-box protein 36
chr10_-_92185071 3.631 NM_008682
Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr3_-_58329780 3.624 NM_030685
Serp1
stress-associated endoplasmic reticulum protein 1
chr3_-_89222140 3.622 NM_016904
Cks1b
CDC28 protein kinase 1b
chr19_+_9016335 3.621 NM_011842
Mta2
metastasis-associated gene family, member 2
chr14_+_55305607 3.618 1700123O20Rik
RIKEN cDNA 1700123O20 gene
chr1_+_66747396 3.605 NM_025683
Rpe
ribulose-5-phosphate-3-epimerase
chr6_-_118369383 3.562 NM_194339
Bms1
BMS1 homolog, ribosome assembly protein (yeast)
chr8_+_109960256 3.536 NM_025830
Wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr7_-_31758185 3.535 Lsr
lipolysis stimulated lipoprotein receptor
chr7_-_134185894 3.523 Kif22
kinesin family member 22
chr8_+_73300712 3.490 2010320M18Rik
RIKEN cDNA 2010320M18 gene
chr11_-_120459646 3.454 NM_011568
Thoc4
THO complex 4
chrX_+_108009728 3.434 NM_008901
Pou3f4
POU domain, class 3, transcription factor 4
chr7_-_134339388 3.429 NM_027353
Cd2bp2
CD2 antigen (cytoplasmic tail) binding protein 2
chr13_-_23654226 3.410 NM_178205
Hist1h3e
histone cluster 1, H3e
chr7_+_107520844 3.401 C2cd3
C2 calcium-dependent domain containing 3
chr5_+_149996135 3.400 NM_001013378
NM_001115149
NM_001115150
NM_001115151
NM_001115153
Uspl1




ubiquitin specific peptidase like 1




chr3_+_95032685 3.397 NM_172395
NM_001038708
Cdc42se1

CDC42 small effector 1

chr1_+_42752608 3.397


chr2_+_132641920 3.358 NM_025676
Mcm8
minichromosome maintenance deficient 8 (S. cerevisiae)
chr5_+_138220097 3.349 NM_027242
2010007H12Rik
RIKEN cDNA 2010007H12 gene
chr4_-_94269802 3.346 Plaa
phospholipase A2, activating protein
chr13_+_17787239 3.338 NM_025479
2810021B07Rik
RIKEN cDNA 2810021B07 gene
chr8_-_114535165 3.329 NM_001130868
NM_053092
Kars

lysyl-tRNA synthetase

chrX_+_93291377 3.329 NM_010833
Msn
moesin
chr1_+_94803538 3.325 NM_175118
Dusp28
dual specificity phosphatase 28
chr11_-_86900256 3.323 NM_024262
1200011M11Rik
RIKEN cDNA 1200011M11 gene
chr16_-_30587549 3.297 NM_178069
Lsg1
large subunit GTPase 1 homolog (S. cerevisiae)
chr19_-_38298606 3.290 NM_001081075
5730455O13Rik
RIKEN cDNA 5730455O13 gene
chr14_-_19103447 3.268 NM_025586
Rpl15
ribosomal protein L15
chr11_+_98219742 3.256 Stard3
START domain containing 3
chr5_+_108494692 3.246 NM_013827
Mtf2
metal response element binding transcription factor 2
chr16_-_23127779 3.241 NM_145480
Rfc4
replication factor C (activator 1) 4
chr12_+_85658045 3.235 NM_144833
Zfp410
zinc finger protein 410
chr3_+_32607582 3.233 Actl6a
actin-like 6A
chr8_+_86239131 3.188 Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr14_+_21167481 3.182 Fam149b
family with sequence similarity 149, member B
chr5_-_38215607 3.179 NM_010835
Msx1
homeobox, msh-like 1
chr6_-_124915441 3.175 Cops7a
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr17_-_37088578 3.171 NM_029632
Ppp1r11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr10_+_79611013 3.163 NM_021565
Midn
midnolin
chr1_-_154472199 3.143 NM_016846
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr8_+_129587894 3.141 NM_001122850
NM_033620
Pard3

par-3 (partitioning defective 3) homolog (C. elegans)

chr3_+_88383528 3.129 NM_025448
Ssr2
signal sequence receptor, beta
chr11_-_70468019 3.124 Pfn1
profilin 1
chrX_+_103222548 3.121 NM_001109757
NM_009726
Atp7a

ATPase, Cu++ transporting, alpha polypeptide

chr16_+_10412017 3.119 NM_011955
Nubp1
nucleotide binding protein 1
chr19_+_36908682 3.117 NM_001163635
Tnks2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr10_-_79896388 3.113 NM_001164147
NM_001164148
NM_001164149
NM_001164150
NM_001164151
NM_001164152
NM_001164153
NM_011548
Tcf3







transcription factor 3







chr11_-_23397858 3.111 Ahsa2
AHA1, activator of heat shock protein ATPase homolog 2 (yeast)
chr10_+_62706600 3.106 NM_026101
Herc4
hect domain and RLD 4
chr13_-_58486515 3.083 NM_027335
2210016F16Rik
RIKEN cDNA 2210016F16 gene
chr12_+_106923552 3.078 NM_178613
4933433P14Rik
RIKEN cDNA 4933433P14 gene
chr1_+_153191613 3.073 NM_001039511
NM_001039512
NM_054102
Ivns1abp


influenza virus NS1A binding protein


chr4_+_108520389 3.072 NM_029571
Kti12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr3_-_107949028 3.072 NM_010306
Gnai3
guanine nucleotide binding protein (G protein), alpha inhibiting 3
chr9_+_103207488 3.068 NM_176979
Topbp1
topoisomerase (DNA) II binding protein 1
chr4_+_133140278 3.068 NM_133884
Gpn2
GPN-loop GTPase 2
chr5_+_129526311 3.046 Ran
RAN, member RAS oncogene family
chr18_-_84758848 3.041 NM_001033341
Zfp407
zinc finger protein 407
chr11_-_93747039 3.031 NM_001013375
Utp18
UTP18, small subunit (SSU) processome component, homolog (yeast)
chr11_+_80242103 3.031 NM_178616
Psmd11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr9_+_110034489 3.025 NM_009211
Smarcc1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr16_+_20672770 3.021 NM_001005331
NM_145941
Eif4g1

eukaryotic translation initiation factor 4, gamma 1

chr2_-_174298383 3.021 Slmo2
slowmo homolog 2 (Drosophila)
chr11_+_72254841 3.021 NM_016776
Mybbp1a
MYB binding protein (P160) 1a
chr14_-_118636251 3.006 NM_177753
Sox21
SRY-box containing gene 21
chr6_+_35202672 3.005 1810058I24Rik
RIKEN cDNA 1810058I24 gene
chr19_+_45080961 3.003 NM_153796
Peo1
progressive external ophthalmoplegia 1 (human)
chr5_-_31210054 3.000 NM_001134692
Ost4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr11_+_29426434 2.998 NM_133767
Mtif2
mitochondrial translational initiation factor 2
chr5_+_3803180 2.994 Krit1
KRIT1, ankyrin repeat containing
chr14_-_52816830 2.981 NM_033618
Supt16h
suppressor of Ty 16 homolog (S. cerevisiae)
chr11_-_120852554 2.974 Csnk1d
casein kinase 1, delta
chr5_-_5514787 2.956 NM_001193660
NM_001193659
NM_001193661
NM_022890
Cldn12



claudin 12



chr7_-_142908061 2.953 NM_001081117
Mki67
antigen identified by monoclonal antibody Ki 67
chr7_+_109118687 2.952 Numa1
nuclear mitotic apparatus protein 1
chr3_+_137806411 2.951 NM_175389
Rg9mtd2
RNA (guanine-9-) methyltransferase domain containing 2
chr5_+_139626176 2.945 NM_001081265
Heatr2
HEAT repeat containing 2
chr12_+_103981919 2.945 NM_177140
D230037D09Rik
RIKEN cDNA D230037D09 gene
chr12_+_86311859 2.942 NM_028632
Fcf1
FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)
chr10_+_87609768 2.941 NM_028334
Nup37
nucleoporin 37
chr12_-_11272479 2.939 NM_177331
Gen1
Gen homolog 1, endonuclease (Drosophila)
chr10_+_4522597 2.935 NM_175374
Mtrf1l
mitochondrial translational release factor 1-like
chr14_+_21167427 2.934 NM_001024512
Fam149b
family with sequence similarity 149, member B
chr6_+_133985717 2.915 NM_007961
Etv6
ets variant gene 6 (TEL oncogene)
chr16_-_64770740 2.894 NM_026273
4930453N24Rik
RIKEN cDNA 4930453N24 gene
chr7_+_86805081 2.890 NM_029835
5730590G19Rik
RIKEN cDNA 5730590G19 gene
chr14_-_21212709 2.882 NM_025440
Mrps16
mitochondrial ribosomal protein S16
chr4_-_59796621 2.878 NM_001013577
1110054O05Rik
RIKEN cDNA 1110054O05 gene
chr7_-_125999115 2.867 NM_001168220
2310008H09Rik
RIKEN cDNA 2310008H09 gene
chr1_-_84835871 2.865 NM_133975
Trip12
thyroid hormone receptor interactor 12
chr6_-_116578909 2.863 Zfp422
zinc finger protein 422
chr3_-_95659666 2.857 NM_027541
Prpf3
PRP3 pre-mRNA processing factor 3 homolog (yeast)
chrX_+_35542969 2.849 NM_001079513
NM_020256
Zbtb33

zinc finger and BTB domain containing 33

chr6_-_124662063 2.847 Emg1
EMG1 nucleolar protein homolog (S. cerevisiae)
chr19_-_55390300 2.841 NM_001033573
NM_025883
Zdhhc6

zinc finger, DHHC domain containing 6


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
2.10 2.02e-64 GO:0044260 cellular macromolecule metabolic process
1.95 1.68e-56 GO:0043170 macromolecule metabolic process
2.40 2.48e-48 GO:0090304 nucleic acid metabolic process
1.73 9.57e-46 GO:0044237 cellular metabolic process
1.70 1.29e-43 GO:0044238 primary metabolic process
2.17 4.16e-43 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.32 9.49e-41 GO:0010467 gene expression
2.01 8.56e-37 GO:0034641 cellular nitrogen compound metabolic process
1.98 4.83e-36 GO:0006807 nitrogen compound metabolic process
1.56 9.73e-35 GO:0008152 metabolic process
2.20 1.44e-30 GO:0016070 RNA metabolic process
2.14 1.11e-28 GO:0009059 macromolecule biosynthetic process
2.13 5.80e-28 GO:0034645 cellular macromolecule biosynthetic process
3.02 1.85e-23 GO:0007049 cell cycle
3.50 4.57e-22 GO:0006396 RNA processing
3.98 2.63e-21 GO:0000278 mitotic cell cycle
4.10 8.04e-21 GO:0016071 mRNA metabolic process
2.00 5.53e-20 GO:0044267 cellular protein metabolic process
4.50 1.33e-19 GO:0008380 RNA splicing
1.80 1.60e-19 GO:0044249 cellular biosynthetic process
3.21 2.19e-19 GO:0022402 cell cycle process
1.78 2.33e-19 GO:0009058 biosynthetic process
4.34 3.74e-19 GO:0006397 mRNA processing
1.96 1.07e-18 GO:0071841 cellular component organization or biogenesis at cellular level
3.39 1.20e-18 GO:0006259 DNA metabolic process
3.47 4.43e-17 GO:0022403 cell cycle phase
4.11 1.50e-16 GO:0006412 translation
3.72 6.06e-16 GO:0000279 M phase
4.43 1.16e-15 GO:0000087 M phase of mitotic cell cycle
1.23 3.87e-15 GO:0009987 cellular process
1.66 4.52e-15 GO:0060255 regulation of macromolecule metabolic process
3.65 6.78e-15 GO:0051301 cell division
4.35 1.37e-14 GO:0000280 nuclear division
4.35 1.37e-14 GO:0007067 mitosis
2.11 2.52e-14 GO:0006996 organelle organization
1.86 4.10e-14 GO:0071842 cellular component organization at cellular level
1.70 4.26e-14 GO:0071840 cellular component organization or biogenesis
4.18 7.47e-14 GO:0048285 organelle fission
1.74 7.88e-14 GO:0019538 protein metabolic process
3.16 3.86e-13 GO:0044265 cellular macromolecule catabolic process
1.54 1.95e-12 GO:0019222 regulation of metabolic process
4.41 2.51e-12 GO:0022613 ribonucleoprotein complex biogenesis
1.59 2.77e-12 GO:0080090 regulation of primary metabolic process
4.74 6.04e-12 GO:0006260 DNA replication
1.69 6.69e-12 GO:0010468 regulation of gene expression
4.18 1.67e-11 GO:0071843 cellular component biogenesis at cellular level
1.70 1.67e-11 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.56 4.17e-11 GO:0031323 regulation of cellular metabolic process
2.80 8.73e-11 GO:0009057 macromolecule catabolic process
1.67 1.04e-10 GO:0010556 regulation of macromolecule biosynthetic process
1.62 1.84e-10 GO:0016043 cellular component organization
3.37 2.41e-09 GO:0006511 ubiquitin-dependent protein catabolic process
2.87 3.01e-09 GO:0006974 response to DNA damage stimulus
3.26 4.30e-09 GO:0051603 proteolysis involved in cellular protein catabolic process
3.29 5.30e-09 GO:0019941 modification-dependent protein catabolic process
1.59 6.66e-09 GO:0031326 regulation of cellular biosynthetic process
3.27 6.85e-09 GO:0043632 modification-dependent macromolecule catabolic process
3.21 7.12e-09 GO:0006281 DNA repair
2.62 7.15e-09 GO:0051276 chromosome organization
3.20 8.07e-09 GO:0044257 cellular protein catabolic process
1.58 1.20e-08 GO:0009889 regulation of biosynthetic process
1.77 1.31e-08 GO:0032774 RNA biosynthetic process
1.76 2.28e-08 GO:0006351 transcription, DNA-dependent
4.22 2.85e-08 GO:0010498 proteasomal protein catabolic process
4.22 2.85e-08 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
3.04 3.01e-08 GO:0030163 protein catabolic process
1.63 3.20e-08 GO:0051252 regulation of RNA metabolic process
4.87 5.32e-08 GO:0007059 chromosome segregation
1.54 3.81e-07 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.60 4.29e-07 GO:0006355 regulation of transcription, DNA-dependent
1.53 5.33e-07 GO:0051171 regulation of nitrogen compound metabolic process
5.66 7.95e-07 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
5.66 7.95e-07 GO:0000398 nuclear mRNA splicing, via spliceosome
5.58 1.05e-06 GO:0000375 RNA splicing, via transesterification reactions
1.81 1.74e-06 GO:0010604 positive regulation of macromolecule metabolic process
3.96 5.79e-06 GO:0042254 ribosome biogenesis
5.36 5.98e-06 GO:0022618 ribonucleoprotein complex assembly
2.55 1.08e-05 GO:0006325 chromatin organization
2.67 1.27e-05 GO:0016568 chromatin modification
5.07 1.61e-05 GO:0071826 ribonucleoprotein complex subunit organization
1.71 2.19e-05 GO:0009893 positive regulation of metabolic process
2.10 2.34e-05 GO:0033554 cellular response to stress
1.73 3.69e-05 GO:0031325 positive regulation of cellular metabolic process
4.80 4.05e-05 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
4.85 8.36e-05 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
4.56 9.51e-05 GO:0051443 positive regulation of ubiquitin-protein ligase activity
4.33 1.00e-04 GO:0006414 translational elongation
2.80 1.05e-04 GO:0010608 posttranscriptional regulation of gene expression
4.45 1.43e-04 GO:0051351 positive regulation of ligase activity
4.23 1.47e-04 GO:0051438 regulation of ubiquitin-protein ligase activity
2.30 1.91e-04 GO:0051247 positive regulation of protein metabolic process
4.14 2.11e-04 GO:0051340 regulation of ligase activity
4.84 2.16e-04 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.53 2.86e-04 GO:0034621 cellular macromolecular complex subunit organization
2.76 3.63e-04 GO:0016567 protein ubiquitination
4.63 4.16e-04 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
4.57 5.12e-04 GO:0051352 negative regulation of ligase activity
4.57 5.12e-04 GO:0051444 negative regulation of ubiquitin-protein ligase activity
2.77 5.26e-04 GO:0034660 ncRNA metabolic process
6.08 5.71e-04 GO:0006413 translational initiation
1.77 6.60e-04 GO:0044085 cellular component biogenesis
1.45 7.39e-04 GO:0048522 positive regulation of cellular process
2.61 8.52e-04 GO:0032446 protein modification by small protein conjugation
2.44 9.56e-04 GO:0070647 protein modification by small protein conjugation or removal
3.62 9.93e-04 GO:0031398 positive regulation of protein ubiquitination
3.92 1.06e-03 GO:0006364 rRNA processing
3.74 1.13e-03 GO:0006310 DNA recombination
1.54 1.31e-03 GO:0043412 macromolecule modification
3.80 1.74e-03 GO:0016072 rRNA metabolic process
1.40 1.94e-03 GO:0048518 positive regulation of biological process
2.20 2.23e-03 GO:0032270 positive regulation of cellular protein metabolic process
1.54 2.58e-03 GO:0006464 protein modification process
1.67 6.57e-03 GO:0051246 regulation of protein metabolic process
6.75 6.63e-03 GO:0000387 spliceosomal snRNP assembly
1.70 8.37e-03 GO:0032268 regulation of cellular protein metabolic process
3.06 8.68e-03 GO:0006417 regulation of translation
1.67 9.12e-03 GO:0044248 cellular catabolic process
5.18 1.01e-02 GO:0000956 nuclear-transcribed mRNA catabolic process
3.68 1.05e-02 GO:0031397 negative regulation of protein ubiquitination
4.11 1.07e-02 GO:0006401 RNA catabolic process
2.71 1.08e-02 GO:0016570 histone modification
2.67 1.43e-02 GO:0016569 covalent chromatin modification
4.59 1.51e-02 GO:0006402 mRNA catabolic process
3.41 1.60e-02 GO:0018205 peptidyl-lysine modification
2.69 1.90e-02 GO:0034470 ncRNA processing
1.65 2.04e-02 GO:0010605 negative regulation of macromolecule metabolic process
4.85 2.05e-02 GO:0006261 DNA-dependent DNA replication
4.12 2.26e-02 GO:0006302 double-strand break repair
2.88 2.36e-02 GO:0031396 regulation of protein ubiquitination
6.48 3.30e-02 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
3.68 4.01e-02 GO:0050657 nucleic acid transport
3.68 4.01e-02 GO:0050658 RNA transport
3.68 4.01e-02 GO:0051236 establishment of RNA localization
3.64 4.67e-02 GO:0006473 protein acetylation
2.44 4.70e-02 GO:0010564 regulation of cell cycle process

Gene overrepresentation in compartment category:

enrichment p-value GO term description
2.16 9.61e-79 GO:0005634 nucleus
1.53 1.56e-73 GO:0005622 intracellular
1.54 1.47e-72 GO:0044424 intracellular part
1.59 3.47e-59 GO:0043229 intracellular organelle
1.58 4.42e-59 GO:0043226 organelle
1.65 5.82e-58 GO:0043231 intracellular membrane-bounded organelle
1.64 1.40e-57 GO:0043227 membrane-bounded organelle
2.77 2.73e-46 GO:0044428 nuclear part
2.62 4.68e-38 GO:0031974 membrane-enclosed lumen
2.64 5.72e-38 GO:0070013 intracellular organelle lumen
2.64 7.64e-38 GO:0043233 organelle lumen
2.77 6.65e-37 GO:0031981 nuclear lumen
1.85 2.52e-33 GO:0044446 intracellular organelle part
1.82 1.63e-31 GO:0044422 organelle part
1.90 8.12e-28 GO:0032991 macromolecular complex
2.04 2.93e-25 GO:0043228 non-membrane-bounded organelle
2.04 2.93e-25 GO:0043232 intracellular non-membrane-bounded organelle
2.73 1.17e-23 GO:0005654 nucleoplasm
1.17 1.37e-18 GO:0005623 cell
1.17 1.37e-18 GO:0044464 cell part
1.37 1.61e-17 GO:0005737 cytoplasm
3.29 9.64e-17 GO:0005694 chromosome
3.20 2.43e-16 GO:0030529 ribonucleoprotein complex
3.26 4.64e-15 GO:0044427 chromosomal part
1.70 5.51e-14 GO:0043234 protein complex
3.16 3.53e-12 GO:0005730 nucleolus
4.69 1.22e-10 GO:0005681 spliceosomal complex
1.85 1.41e-09 GO:0005829 cytosol
5.57 8.43e-09 GO:0071013 catalytic step 2 spliceosome
2.24 3.83e-08 GO:0044451 nucleoplasm part
4.05 2.56e-05 GO:0000793 condensed chromosome
2.94 3.91e-05 GO:0000228 nuclear chromosome
3.45 6.20e-05 GO:0000775 chromosome, centromeric region
10.91 3.12e-04 GO:0005852 eukaryotic translation initiation factor 3 complex
1.25 4.46e-04 GO:0044444 cytoplasmic part
2.70 5.70e-04 GO:0000785 chromatin
6.33 6.62e-04 GO:0005657 replication fork
1.94 1.04e-03 GO:0015630 microtubule cytoskeleton
2.80 1.07e-03 GO:0044454 nuclear chromosome part
4.47 1.57e-03 GO:0000502 proteasome complex
3.32 2.36e-03 GO:0000151 ubiquitin ligase complex
1.53 2.71e-03 GO:0005856 cytoskeleton
2.76 3.35e-03 GO:0005840 ribosome
3.23 3.48e-03 GO:0005819 spindle
2.48 4.52e-03 GO:0005815 microtubule organizing center
3.53 6.19e-03 GO:0000776 kinetochore
3.93 6.82e-03 GO:0031461 cullin-RING ubiquitin ligase complex
5.36 9.72e-03 GO:0022627 cytosolic small ribosomal subunit
4.37 1.05e-02 GO:0015935 small ribosomal subunit
11.26 1.05e-02 GO:0031080 Nup107-160 complex
2.43 1.79e-02 GO:0005813 centrosome
2.77 1.82e-02 GO:0016604 nuclear body
4.31 2.71e-02 GO:0022626 cytosolic ribosome
6.17 2.89e-02 GO:0030532 small nuclear ribonucleoprotein complex
5.91 3.90e-02 GO:0005689 U12-type spliceosomal complex

Gene overrepresentation in function category:

enrichment p-value GO term description
2.12 3.53e-31 GO:0003676 nucleic acid binding
2.92 1.36e-19 GO:0003723 RNA binding
1.26 6.49e-15 GO:0005488 binding
1.87 3.87e-12 GO:0003677 DNA binding
5.01 3.95e-08 GO:0008135 translation factor activity, nucleic acid binding
1.58 8.34e-07 GO:0000166 nucleotide binding
1.30 1.98e-06 GO:0005515 protein binding
5.50 6.83e-06 GO:0003743 translation initiation factor activity
2.30 7.21e-05 GO:0016874 ligase activity
3.18 5.89e-04 GO:0003713 transcription coactivator activity
2.36 6.79e-04 GO:0008134 transcription factor binding
1.51 7.26e-04 GO:0035639 purine ribonucleoside triphosphate binding
2.53 1.19e-03 GO:0000988 protein binding transcription factor activity
1.56 1.20e-03 GO:0005524 ATP binding
1.49 1.49e-03 GO:0017076 purine nucleotide binding
1.54 1.98e-03 GO:0030554 adenyl nucleotide binding
1.48 1.98e-03 GO:0032555 purine ribonucleotide binding
1.48 2.04e-03 GO:0032553 ribonucleotide binding
2.49 2.43e-03 GO:0003712 transcription cofactor activity
2.48 2.64e-03 GO:0000989 transcription factor binding transcription factor activity
1.53 2.67e-03 GO:0032559 adenyl ribonucleotide binding
4.85 4.57e-03 GO:0004812 aminoacyl-tRNA ligase activity
4.85 4.57e-03 GO:0016875 ligase activity, forming carbon-oxygen bonds
4.85 4.57e-03 GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
1.51 1.28e-02 GO:0008270 zinc ion binding
3.46 1.86e-02 GO:0035257 nuclear hormone receptor binding
2.73 2.76e-02 GO:0004518 nuclease activity
2.44 4.38e-02 GO:0004842 ubiquitin-protein ligase activity