Motif ID: ESRRA.p2

Z-value: 2.800

Transcription factors associated with ESRRA.p2:

NameEntrezDescription
Esrra 26379 estrogen related receptor, alpha

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Esrrachr19_-_69961890.241.6e-01Click!


Activity profile for motif ESRRA.p2.

activity profile for motif ESRRA.p2


Sorted Z-values histogram for motif ESRRA.p2

Sorted Z-values for motif ESRRA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESRRA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr7_-_148615247 27.766 NM_021316
Cend1
cell cycle exit and neuronal differentiation 1
chr10_+_75398588 27.218 Chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr15_-_83936038 26.306 Sult4a1
sulfotransferase family 4A, member 1
chr4_-_8166182 24.377 NM_007592
Car8
carbonic anhydrase 8
chr15_+_79921725 22.399 NM_009303
NM_207708
Syngr1

synaptogyrin 1

chr9_+_107242932 22.090 NM_175486
6430571L13Rik
RIKEN cDNA 6430571L13 gene
chr2_-_180891448 21.916 Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr10_+_79179326 21.913 NM_008226
Hcn2
hyperpolarization-activated, cyclic nucleotide-gated K+ 2
chr6_+_113232319 19.976 Cpne9
copine family member IX
chr2_+_25118144 19.398 Tprn
taperin
chr2_+_121184334 16.466 NM_009897
Ckmt1
creatine kinase, mitochondrial 1, ubiquitous
chr5_-_108978950 15.689 NM_007756
Cplx1
complexin 1
chr13_+_83663817 14.947 Mef2c
myocyte enhancer factor 2C
chr2_+_32442585 13.967 St6galnac4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr5_-_46030523 13.808 NM_021416
Fam184b
family with sequence similarity 184, member B
chr12_+_110783593 13.385 Meg3
maternally expressed 3
chr11_+_68902025 13.315 NM_009497
Vamp2
vesicle-associated membrane protein 2
chr8_-_13494457 12.860 NM_019521
Gas6
growth arrest specific 6
chr11_+_68901989 12.201 Vamp2
vesicle-associated membrane protein 2
chr15_+_82086506 11.578 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr13_+_118391270 11.450 Hcn1
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr2_+_129419252 11.396 Sirpa
signal-regulatory protein alpha
chr11_+_6963421 11.327 NM_009622
Adcy1
adenylate cyclase 1
chr7_+_51846254 11.033 NM_008422
Kcnc3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr14_+_14117313 10.703 Synpr
synaptoporin
chr6_+_38613031 10.630 NM_001101507
Clec2l
C-type lectin domain family, member L
chr2_-_73749317 10.538 NM_175015
Atp5g3
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)
chr19_-_5085487 10.425 Tmem151a
transmembrane protein 151A
chr7_-_88851798 10.383 NM_001164086
NM_011983
Homer2

homer homolog 2 (Drosophila)

chr18_-_61173753 10.239 NM_201353
Slc6a7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr11_+_98603041 10.213 Thra
thyroid hormone receptor alpha
chr2_+_121121189 10.095 NM_001173506
Mtap1a
microtubule-associated protein 1 A
chr6_-_113991945 9.775 NM_009723
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr2_+_32442620 9.703 St6galnac4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr14_-_22668093 9.292 NM_026965
Comtd1
catechol-O-methyltransferase domain containing 1
chr15_+_22966203 9.077 NM_001081299
Cdh18
cadherin 18
chr16_+_13940720 8.791 NM_033564
Mpv17l
Mpv17 transgene, kidney disease mutant-like
chr11_-_54846882 8.576 NM_001110211
NM_013472
Anxa6

annexin A6

chr12_+_103793130 8.431 NM_007693
Chga
chromogranin A
chr19_-_47165137 8.395 Usmg5
upregulated during skeletal muscle growth 5
chr6_-_24477665 8.342 NM_026614
Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr9_-_53418394 8.060 NM_144784
Acat1
acetyl-Coenzyme A acetyltransferase 1
chr1_-_169323901 7.991 NM_025569
Mgst3
microsomal glutathione S-transferase 3
chr11_-_107776248 7.836 Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr9_-_29770699 7.708 NM_172290
Ntm
neurotrimin
chr18_+_33098694 7.636 NM_009793
Camk4
calcium/calmodulin-dependent protein kinase IV
chr3_+_27081918 7.615 NM_178772
Nceh1
arylacetamide deacetylase-like 1
chr5_+_107926763 7.537 NM_001007574
NM_001168557
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr6_+_48487648 7.431 Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
chr14_-_52532988 7.130 Ndrg2
N-myc downstream regulated gene 2
chr3_-_87804277 7.079 NM_001109758
NM_007529
Bcan

brevican

chr7_-_25790888 7.027 NM_144921
Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr11_-_115128540 6.724 NM_010350
Grin2c
glutamate receptor, ionotropic, NMDA2C (epsilon 3)
chr8_+_98226914 6.634 NM_001195006
NM_145602
Ndrg4

N-myc downstream regulated gene 4

chr5_+_52755183 6.390 Sod3
superoxide dismutase 3, extracellular
chr14_-_52533039 6.232 Ndrg2
N-myc downstream regulated gene 2
chr11_-_3995299 6.184 NM_026443
Mtfp1
mitochondrial fission process 1
chr9_-_57315800 5.961 NM_020270
Scamp5
secretory carrier membrane protein 5
chr16_+_17276434 5.947 Tmem191c
transmembrane protein 191C
chr15_-_79635156 5.946 Nptxr
neuronal pentraxin receptor
chr8_-_3624988 5.858 NM_001129804
Pcp2
Purkinje cell protein 2 (L7)
chr7_-_25757587 5.858 NM_010261
Rabac1
Rab acceptor 1 (prenylated)
chr7_+_19469999 5.846 NM_009402
Pglyrp1
peptidoglycan recognition protein 1
chr9_+_56712850 5.841 NM_139001
Cspg4
chondroitin sulfate proteoglycan 4
chr1_+_138028025 5.810 Kif21b
kinesin family member 21B
chr15_-_35867898 5.809 NM_053071
Cox6c
cytochrome c oxidase, subunit VIc
chr12_+_110783786 5.758 Meg3
maternally expressed 3
chr19_-_4615180 5.755 Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr10_-_90586724 5.736 Slc25a3
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
chr2_+_177876635 5.659 NM_028806
Phactr3
phosphatase and actin regulator 3
chr11_-_3404756 5.651 NM_172439
Inpp5j
inositol polyphosphate 5-phosphatase J
chr2_+_91898868 5.617


chr8_-_87461220 5.591 Mast1
microtubule associated serine/threonine kinase 1
chr15_-_74583382 5.574 NM_011838
Lynx1
Ly6/neurotoxin 1
chr3_-_87804062 5.562 Bcan
brevican
chr15_+_30102306 5.426 NM_008729
Ctnnd2
catenin (cadherin associated protein), delta 2
chr11_+_75007300 5.354 Rtn4rl1
reticulon 4 receptor-like 1
chr19_-_47165086 5.251 NM_023211
Usmg5
upregulated during skeletal muscle growth 5
chr16_+_17646562 5.068 NM_001166164
Ccdc74a
coiled-coil domain containing 74A
chr16_-_84835213 5.046 Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr6_-_113481546 5.041 NM_175101
Tmem111
transmembrane protein 111
chr7_+_17529961 5.001 NM_001099636
Pnmal2
PNMA-like 2
chr16_+_17276384 4.939 NM_177473
Tmem191c
transmembrane protein 191C
chr2_-_26883441 4.906 NM_001177627
NM_172659
Slc2a6

solute carrier family 2 (facilitated glucose transporter), member 6

chr7_-_31840647 4.873 NM_019503
NM_052992
Fxyd1

FXYD domain-containing ion transport regulator 1

chr15_+_3220999 4.774 Sepp1
selenoprotein P, plasma, 1
chr9_-_35018552 4.766 Foxred1
FAD-dependent oxidoreductase domain containing 1
chr10_+_93661746 4.751 NM_025551
Ndufa12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr6_-_113451811 4.713 NM_172487
Prrt3
proline-rich transmembrane protein 3
chr11_-_113427050 4.670 NM_001166503
NM_027216
Slc39a11

solute carrier family 39 (metal ion transporter), member 11

chr15_+_88692885 4.650 Pim3
proviral integration site 3
chr4_-_82151657 4.596 Nfib
nuclear factor I/B
chr1_-_122017495 4.530 NM_001037999
Dbi
diazepam binding inhibitor
chr19_-_43598949 4.520 NM_010324
Got1
glutamate oxaloacetate transaminase 1, soluble
chr1_-_79855177 4.488 Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr7_-_88851662 4.476 Homer2
homer homolog 2 (Drosophila)
chr7_+_112702873 4.370 NM_011421
Smpd1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr2_+_128891655 4.356 NM_027192
Ttl
tubulin tyrosine ligase
chr6_-_113481340 4.273 Tmem111
transmembrane protein 111
chr3_+_14886253 4.257 NM_009801
Car2
carbonic anhydrase 2
chr9_+_54434140 4.248 NM_029573
Idh3a
isocitrate dehydrogenase 3 (NAD+) alpha
chr1_-_174228105 4.218 NM_178405
Atp1a2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr12_+_62625477 4.173 NM_178714
Lrfn5
leucine rich repeat and fibronectin type III domain containing 5
chr10_-_77927652 4.144 NM_172134
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr9_+_107199169 4.142 Cish
cytokine inducible SH2-containing protein
chr4_+_99602038 4.130 NM_028132
Pgm2
phosphoglucomutase 2
chr19_-_57389371 4.089 Ablim1
actin-binding LIM protein 1
chr15_+_100592177 4.072 NM_021530
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr4_+_84851440 4.035 Sh3gl2
SH3-domain GRB2-like 2
chr6_-_126116761 4.002 NM_001164034
NM_008742
Ntf3

neurotrophin 3

chr6_+_72389009 3.995 4930414L22Rik
RIKEN cDNA 4930414L22 gene
chr15_+_7079540 3.925 NM_001113386
Lifr
leukemia inhibitory factor receptor
chr2_+_143371807 3.832 NM_008792
Pcsk2
proprotein convertase subtilisin/kexin type 2
chr17_-_34987137 3.821 NM_021337
Skiv2l
superkiller viralicidic activity 2-like (S. cerevisiae)
chr11_-_99105293 3.819 NM_172946
Krt222
keratin 222
chr7_+_17530050 3.804 Pnmal2
PNMA-like 2
chr7_-_31699850 3.793 NM_010758
Mag
myelin-associated glycoprotein
chr5_+_58109278 3.766 Pcdh7
protocadherin 7
chr12_-_72237590 3.741 NM_001024853
NM_001024854
NM_013896
Timm9


translocase of inner mitochondrial membrane 9 homolog (yeast)


chr11_-_61307598 3.714 NM_011841
Mapk7
mitogen-activated protein kinase 7
chr15_+_3220994 3.662 Sepp1
selenoprotein P, plasma, 1
chr3_-_36589048 3.652 NM_019510
Trpc3
transient receptor potential cation channel, subfamily C, member 3
chr19_-_7054901 3.648 NM_008020
NM_001166368
Fkbp2

FK506 binding protein 2

chr2_-_167318313 3.636 NM_170756
Spata2
spermatogenesis associated 2
chr13_+_118391126 3.609 NM_010408
Hcn1
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr17_-_25922419 3.600 Haghl
hydroxyacylglutathione hydrolase-like
chr6_-_124764170 3.594 Tpi1
triosephosphate isomerase 1
chr6_+_125095236 3.567 NM_178787
NM_001039669
Iffo1

intermediate filament family orphan 1

chr1_-_137064124 3.552 NM_134438
Gpr37l1
G protein-coupled receptor 37-like 1
chr3_+_104442568 3.547 NM_009196
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr8_+_96676506 3.534 NM_013603
Mt3
metallothionein 3
chrX_-_50946805 3.527 NM_024170
Cxx1a
CAAX box 1 homolog A (human)
chr10_-_114688480 3.501 NM_025706
Tbc1d15
TBC1 domain family, member 15
chr11_+_70460758 3.476 Rnf167
ring finger protein 167
chr13_-_105844882 3.443 NM_029879
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr7_+_3568955 3.442 NM_025348
Ndufa3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr10_+_78037170 3.433 NM_173751
Ilvbl
ilvB (bacterial acetolactate synthase)-like
chr2_+_25118098 3.421 NM_175286
Tprn
taperin
chr8_+_63111621 3.381 NM_027756
Mfap3l
microfibrillar-associated protein 3-like
chr10_-_10802102 3.367 NM_001114333
NM_016976
Grm1

glutamate receptor, metabotropic 1

chr10_+_80318009 3.333 NM_175195
3110056O03Rik
RIKEN cDNA 3110056O03 gene
chr3_-_89049756 3.267 NM_183037
Trim46
tripartite motif-containing 46
chr19_-_3912727 3.256 Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr8_+_122386155 3.206 NM_146219
Klhl36
kelch-like 36 (Drosophila)
chr8_-_3625251 3.197 NM_008790
Pcp2
Purkinje cell protein 2 (L7)
chr10_-_79446910 3.184 NM_001003949
ORF61
open reading frame 61
chr12_+_112512884 3.180 Amn
amnionless
chr9_-_44728786 3.133 Atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr1_+_75432496 3.055 NM_133708
Gmppa
GDP-mannose pyrophosphorylase A
chr10_-_70807521 3.050 NM_134007
Cisd1
CDGSH iron sulfur domain 1
chr15_-_86016070 3.005 Cerk
ceramide kinase
chr4_-_8166157 2.993 Car8
carbonic anhydrase 8
chr19_+_8665743 2.979 NM_001164634
NM_031194
Slc22a8

solute carrier family 22 (organic anion transporter), member 8

chr4_-_49858561 2.967 Grin3a
glutamate receptor ionotropic, NMDA3A
chr1_+_138027943 2.956 NM_001039472
Kif21b
kinesin family member 21B
chr6_+_90500776 2.947 NM_027406
Aldh1l1
aldehyde dehydrogenase 1 family, member L1
chr17_-_26005680 2.940 NM_026633
Fam195a
family with sequence similarity 195, member A
chr9_+_109834324 2.938 Mtap4
microtubule-associated protein 4
chr2_+_70312979 2.913 NM_022435
Sp5
trans-acting transcription factor 5
chr4_+_62021728 2.911 NM_175090
Slc31a1
solute carrier family 31, member 1
chr2_+_151931424 2.880 Srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
chr16_-_4789939 2.781


chr19_-_37281951 2.750 Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr5_+_118477803 2.749 NM_021344
Tesc
tescalcin
chr6_+_113232300 2.746 NM_170673
Cpne9
copine family member IX
chrX_-_50973482 2.733 NM_001018063
Cxx1b
CAAX box 1 homolog B (human)
chr9_+_107904919 2.712 NM_013785
Ip6k1
inositol hexaphosphate kinase 1
chr1_+_78306890 2.703 NM_001004173
Sgpp2
sphingosine-1-phosphate phosphotase 2
chr6_-_91423479 2.697 Chchd4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr2_+_151368331 2.686 Fkbp1a
FK506 binding protein 1a
chr17_-_34987150 2.684 Skiv2l
superkiller viralicidic activity 2-like (S. cerevisiae)
chr5_+_151062363 2.616 NM_172887
Fry
furry homolog (Drosophila)
chr2_+_26483976 2.615 NM_019833
Fam69b
family with sequence similarity 69, member B
chr11_+_70658261 2.579 NM_019400
Rabep1
rabaptin, RAB GTPase binding effector protein 1
chr17_-_66868909 2.575 NM_024448
Rab12
RAB12, member RAS oncogene family
chr4_+_137806293 2.570 NM_001099631
Sh2d5
SH2 domain containing 5
chr11_-_116060026 2.547 Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr15_-_35867884 2.544 Cox6c
cytochrome c oxidase, subunit VIc
chr2_+_139996381 2.520 NM_027093
2310003L22Rik
RIKEN cDNA 2310003L22 gene
chr13_-_74487687 2.519 NM_023281
Sdha
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr14_+_55082960 2.471 NM_022993
Lrp10
low-density lipoprotein receptor-related protein 10
chr18_+_37637421 2.461 NM_053141
Pcdhb16
protocadherin beta 16
chr7_+_29610281 2.459 NM_016772
Ech1
enoyl coenzyme A hydratase 1, peroxisomal
chr17_-_34257327 2.452 NM_001025387
Brd2
bromodomain containing 2
chr1_+_34858544 2.405 NM_183019
Arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr12_-_112910475 2.397 NM_021273
Ckb
creatine kinase, brain
chr9_+_57758783 2.331 NM_001122873
NM_027086
Ubl7

ubiquitin-like 7 (bone marrow stromal cell-derived)

chr1_-_166387998 2.323 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr14_-_55527674 2.308 Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr9_-_44728790 2.306 NM_013795
Atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr9_+_56712829 2.303 Cspg4
chondroitin sulfate proteoglycan 4
chr7_-_88851823 2.298 Homer2
homer homolog 2 (Drosophila)
chr2_+_18594027 2.275 NM_147778
Commd3
COMM domain containing 3
chr8_-_125777949 2.272 NM_028200
1300018I17Rik
RIKEN cDNA 1300018I17 gene
chr9_-_35018518 2.267 Foxred1
FAD-dependent oxidoreductase domain containing 1
chr14_+_77556569 2.264 Enox1
ecto-NOX disulfide-thiol exchanger 1
chr5_-_125538755 2.231 Ncor2
nuclear receptor co-repressor 2
chr15_+_99869071 2.216 NM_001159361
Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr15_-_34608600 2.216 Nipal2
NIPA-like domain containing 2
chr4_+_132925684 2.215 NM_016981
Slc9a1
solute carrier family 9 (sodium/hydrogen exchanger), member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
2.48 2.01e-14 GO:0006810 transport
2.43 5.95e-14 GO:0051234 establishment of localization
2.23 5.56e-13 GO:0051179 localization
3.40 2.48e-08 GO:0006811 ion transport
3.90 2.70e-08 GO:0006812 cation transport
5.88 2.40e-07 GO:0006091 generation of precursor metabolites and energy
3.26 2.73e-06 GO:0055085 transmembrane transport
3.60 2.04e-05 GO:0030001 metal ion transport
10.50 1.69e-04 GO:0006754 ATP biosynthetic process
6.84 6.45e-04 GO:0022900 electron transport chain
8.93 7.05e-04 GO:0009206 purine ribonucleoside triphosphate biosynthetic process
8.80 8.02e-04 GO:0009145 purine nucleoside triphosphate biosynthetic process
8.80 8.02e-04 GO:0009201 ribonucleoside triphosphate biosynthetic process
25.56 8.86e-04 GO:0015985 energy coupled proton transport, down electrochemical gradient
25.56 8.86e-04 GO:0015986 ATP synthesis coupled proton transport
8.55 1.03e-03 GO:0009142 nucleoside triphosphate biosynthetic process
4.85 1.34e-03 GO:0050804 regulation of synaptic transmission
6.00 2.40e-03 GO:0006164 purine nucleotide biosynthetic process
4.50 3.26e-03 GO:0051969 regulation of transmission of nerve impulse
3.74 3.60e-03 GO:0015672 monovalent inorganic cation transport
3.72 3.93e-03 GO:0034220 ion transmembrane transport
8.58 4.05e-03 GO:0015992 proton transport
5.63 4.46e-03 GO:0072522 purine-containing compound biosynthetic process
8.44 4.58e-03 GO:0006818 hydrogen transport
7.12 4.86e-03 GO:0009152 purine ribonucleotide biosynthetic process
6.72 7.86e-03 GO:0009260 ribonucleotide biosynthetic process
4.14 8.54e-03 GO:0031644 regulation of neurological system process
2.40 1.89e-02 GO:0022008 neurogenesis
3.41 2.22e-02 GO:0046903 secretion
4.66 2.69e-02 GO:0009165 nucleotide biosynthetic process
2.10 2.76e-02 GO:0007399 nervous system development
3.06 2.90e-02 GO:0044057 regulation of system process
2.84 3.13e-02 GO:0005975 carbohydrate metabolic process
3.15 3.41e-02 GO:0044262 cellular carbohydrate metabolic process
3.27 3.78e-02 GO:0019226 transmission of nerve impulse
3.27 3.78e-02 GO:0035637 multicellular organismal signaling
3.00 3.79e-02 GO:0007267 cell-cell signaling
3.61 3.94e-02 GO:0007268 synaptic transmission
3.08 4.49e-02 GO:0007610 behavior
4.41 4.49e-02 GO:0034404 nucleobase, nucleoside and nucleotide biosynthetic process
4.41 4.49e-02 GO:0034654 nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process
2.36 4.94e-02 GO:0055114 oxidation-reduction process

Gene overrepresentation in compartment category:

enrichment p-value GO term description
1.87 4.33e-15 GO:0044444 cytoplasmic part
1.60 4.95e-14 GO:0016020 membrane
5.41 5.59e-13 GO:0031966 mitochondrial membrane
5.18 1.95e-12 GO:0005740 mitochondrial envelope
3.15 4.41e-12 GO:0031090 organelle membrane
5.93 7.90e-12 GO:0005743 mitochondrial inner membrane
5.63 2.94e-11 GO:0019866 organelle inner membrane
1.52 3.47e-10 GO:0005737 cytoplasm
4.11 1.20e-09 GO:0044429 mitochondrial part
2.66 1.65e-09 GO:0005739 mitochondrion
1.58 1.77e-09 GO:0044425 membrane part
3.68 1.12e-08 GO:0031975 envelope
3.63 3.22e-08 GO:0031967 organelle envelope
1.21 3.56e-08 GO:0005623 cell
1.21 3.56e-08 GO:0044464 cell part
4.04 3.61e-08 GO:0045202 synapse
7.75 8.92e-06 GO:0044455 mitochondrial membrane part
1.51 2.07e-05 GO:0016021 integral to membrane
1.49 2.41e-05 GO:0031224 intrinsic to membrane
7.39 5.31e-05 GO:0008021 synaptic vesicle
3.12 6.20e-05 GO:0043005 neuron projection
22.16 3.67e-04 GO:0045259 proton-transporting ATP synthase complex
4.09 4.06e-04 GO:0030424 axon
3.05 4.41e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
1.26 5.34e-04 GO:0044424 intracellular part
1.24 9.85e-04 GO:0005622 intracellular
2.89 1.08e-03 GO:0031988 membrane-bounded vesicle
2.59 1.22e-03 GO:0031410 cytoplasmic vesicle
2.53 1.31e-03 GO:0031982 vesicle
4.81 1.53e-03 GO:0030135 coated vesicle
3.51 1.53e-03 GO:0043025 neuronal cell body
3.40 2.38e-03 GO:0044456 synapse part
5.01 2.47e-03 GO:0030136 clathrin-coated vesicle
3.35 2.88e-03 GO:0044297 cell body
10.78 3.21e-03 GO:0016469 proton-transporting two-sector ATPase complex
8.46 3.29e-03 GO:0070469 respiratory chain
2.25 4.10e-03 GO:0005794 Golgi apparatus
2.15 4.16e-03 GO:0042995 cell projection
22.16 4.20e-03 GO:0005753 mitochondrial proton-transporting ATP synthase complex
1.30 5.25e-03 GO:0043231 intracellular membrane-bounded organelle
3.50 5.42e-03 GO:0030425 dendrite
1.29 5.93e-03 GO:0043227 membrane-bounded organelle
33.23 1.22e-02 GO:0005890 sodium:potassium-exchanging ATPase complex
8.49 1.31e-02 GO:0005746 mitochondrial respiratory chain
1.25 1.37e-02 GO:0043229 intracellular organelle
16.62 1.47e-02 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain
1.25 1.63e-02 GO:0043226 organelle
4.87 1.90e-02 GO:0031301 integral to organelle membrane
1.50 1.96e-02 GO:0005886 plasma membrane
24.93 3.33e-02 GO:0017146 N-methyl-D-aspartate selective glutamate receptor complex
24.93 3.33e-02 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)
9.23 3.56e-02 GO:0005747 mitochondrial respiratory chain complex I
9.23 3.56e-02 GO:0030964 NADH dehydrogenase complex
9.23 3.56e-02 GO:0045271 respiratory chain complex I
1.44 3.60e-02 GO:0044446 intracellular organelle part
1.47 3.85e-02 GO:0071944 cell periphery
1.43 4.20e-02 GO:0044422 organelle part
1.93 4.39e-02 GO:0000267 cell fraction

Gene overrepresentation in function category:

enrichment p-value GO term description
3.53 8.43e-11 GO:0022857 transmembrane transporter activity
3.89 2.37e-10 GO:0015075 ion transmembrane transporter activity
4.43 5.62e-10 GO:0008324 cation transmembrane transporter activity
3.56 9.41e-10 GO:0022891 substrate-specific transmembrane transporter activity
3.07 1.80e-09 GO:0005215 transporter activity
3.26 4.41e-09 GO:0022892 substrate-specific transporter activity
6.78 5.38e-09 GO:0022890 inorganic cation transmembrane transporter activity
7.24 2.27e-07 GO:0015077 monovalent inorganic cation transmembrane transporter activity
8.52 7.80e-05 GO:0015078 hydrogen ion transmembrane transporter activity
1.48 7.20e-04 GO:0003824 catalytic activity
5.81 9.74e-04 GO:0046873 metal ion transmembrane transporter activity
3.91 2.38e-03 GO:0048037 cofactor binding
3.48 5.19e-03 GO:0022804 active transmembrane transporter activity
33.23 1.98e-02 GO:0004972 N-methyl-D-aspartate selective glutamate receptor activity
4.06 2.77e-02 GO:0050662 coenzyme binding
6.05 4.79e-02 GO:0015081 sodium ion transmembrane transporter activity