Motif ID: FOSL2.p2

Z-value: 0.592

Transcription factors associated with FOSL2.p2:

NameEntrezDescription
Fosl2 14284 fos-like antigen 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Fosl2chr5_+_324382190.539.7e-04Click!


Activity profile for motif FOSL2.p2.

activity profile for motif FOSL2.p2


Sorted Z-values histogram for motif FOSL2.p2

Sorted Z-values for motif FOSL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOSL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr2_+_156301543 5.482 NM_001006664
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr14_+_66587319 4.712 NM_013492
Clu
clusterin
chr14_+_35124004 4.257 Glud1
glutamate dehydrogenase 1
chr8_+_97508270 2.883 NM_018882
Gpr56
G protein-coupled receptor 56
chr8_+_98226914 2.863 NM_001195006
NM_145602
Ndrg4

N-myc downstream regulated gene 4

chr18_-_15562126 2.855 NM_009700
Aqp4
aquaporin 4
chr8_-_3625251 2.752 NM_008790
Pcp2
Purkinje cell protein 2 (L7)
chr10_-_76188683 2.534 NM_009933
Col6a1
collagen, type VI, alpha 1
chr2_-_17652669 2.505 NM_028757
Nebl
nebulette
chr2_+_136539202 2.495 Snap25
synaptosomal-associated protein 25
chr18_+_33098694 2.457 NM_009793
Camk4
calcium/calmodulin-dependent protein kinase IV
chr2_+_136539143 2.446 NM_011428
Snap25
synaptosomal-associated protein 25
chr9_-_121404750 2.210 Cck
cholecystokinin
chr10_+_128346900 1.993 NM_007653
Cd63
CD63 antigen
chr2_+_131735663 1.970 NM_011170
Prnp
prion protein
chr11_-_69479553 1.947 NM_009853
Cd68
CD68 antigen
chr14_-_79701303 1.921 NM_025427
1190002H23Rik
RIKEN cDNA 1190002H23 gene
chr1_-_79436564 1.882 NM_009129
Scg2
secretogranin II
chr10_+_4424140 1.841 NM_001161822
NM_019958
Rgs17

regulator of G-protein signaling 17

chr3_-_88307024 1.792 Lmna
lamin A
chr6_-_124719465 1.679 NM_013509
Eno2
enolase 2, gamma neuronal
chr10_+_128370814 1.644 NM_008398
Itga7
integrin alpha 7
chr3_-_107320881 1.636 NM_172271
Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr12_+_31950097 1.630 NM_008482
Lamb1
laminin B1
chr6_+_66986637 1.573 E230016M11Rik
RIKEN cDNA E230016M11 gene
chr3_+_122970332 1.569 NM_027135
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr18_+_38115192 1.527 NM_153793
Rell2
RELT-like 2
chr13_-_61037894 1.493 NM_001145799
Ctla2a
cytotoxic T lymphocyte-associated protein 2 alpha
chr1_-_33964439 1.424 NM_177235
Bend6
BEN domain containing 6
chr2_+_138104219 1.382 NM_145534
Btbd3
BTB (POZ) domain containing 3
chr9_-_121404799 1.345 NM_031161
Cck
cholecystokinin
chr10_+_59740430 1.338 Psap
prosaposin
chr17_-_90487479 1.290 Nrxn1
neurexin I
chr7_-_116925058 1.260 NM_020610
Nrip3
nuclear receptor interacting protein 3
chr1_+_109486582 1.210 NM_001159748
NM_011459
Serpinb8

serine (or cysteine) peptidase inhibitor, clade B, member 8

chr7_+_52960585 1.208 NM_016974
Dbp
D site albumin promoter binding protein
chr7_+_146574969 1.205 NM_001127363
NM_183144
Inpp5a

inositol polyphosphate-5-phosphatase A

chr6_+_42300005 1.180 Zyx
zyxin
chr3_-_107320831 1.167 Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr2_+_134611879 1.162 NM_001145830
NM_019677
Plcb1

phospholipase C, beta 1

chrX_-_7709907 1.151 NM_026137
Wdr13
WD repeat domain 13
chr11_-_100576628 1.130


chr2_+_25251393 1.101 NM_009849
Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
chr15_-_90509751 1.076 NM_001033851
NM_025815
Cpne8

copine VIII

chr11_-_51464543 1.066 NM_145974
N4bp3
NEDD4 binding protein 3
chr19_-_38199291 1.065 NM_011255
Rbp4
retinol binding protein 4, plasma
chr17_+_45692647 1.063 NM_008690
Nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr7_-_90883999 1.050 NM_010551
Il16
interleukin 16
chr11_-_100831909 1.041 NM_008986
Ptrf
polymerase I and transcript release factor
chrX_-_132738383 1.035 NM_177919
Tceal5
transcription elongation factor A (SII)-like 5
chr17_-_45729199 1.021 NM_022880
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr2_+_151931424 1.020 Srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
chr7_+_91677480 1.007 Gm2115
predicted gene 2115
chr18_+_61265225 0.998 NM_001037859
Csf1r
colony stimulating factor 1 receptor
chr13_-_56397521 0.994 Cxcl14
chemokine (C-X-C motif) ligand 14
chr14_+_35123922 0.963 Glud1
glutamate dehydrogenase 1
chr7_+_135667095 0.962 NM_013863
Bag3
BCL2-associated athanogene 3
chr7_-_112630662 0.952 NM_028444
Prkcdbp
protein kinase C, delta binding protein
chr9_-_91260619 0.949 NM_009573
Zic1
zinc finger protein of the cerebellum 1
chr9_-_86589782 0.918 NM_008615
Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr7_-_53176582 0.877 NM_010129
Emp3
epithelial membrane protein 3
chr2_+_61884596 0.866 NM_033552
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr18_+_23656024 0.852 Dtna
dystrobrevin alpha
chr6_+_129483295 0.850 Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr15_-_58654964 0.847 NM_175212
Tmem65
transmembrane protein 65
chr7_-_30980042 0.847 NM_009795
Capns1
calpain, small subunit 1
chr1_-_134036041 0.840 NM_008795
Cdk18
cyclin-dependent kinase 18
chr11_+_54128404 0.838 NM_001033599
Acsl6
acyl-CoA synthetase long-chain family member 6
chr19_+_8665743 0.832 NM_001164634
NM_031194
Slc22a8

solute carrier family 22 (organic anion transporter), member 8

chr9_+_96096690 0.816 NM_001184706
NM_001184708
NM_178667
Tfdp2


transcription factor Dp 2


chr3_-_88307198 0.804 Lmna
lamin A
chr15_+_54402914 0.804 NM_178920
Mal2
mal, T-cell differentiation protein 2
chr19_+_9063730 0.795 NM_001039959
NM_009643
Ahnak

AHNAK nucleoprotein (desmoyokin)

chr5_-_149363603 0.788 Ubl3
ubiquitin-like 3
chr15_-_74583382 0.782 NM_011838
Lynx1
Ly6/neurotoxin 1
chr6_+_48986625 0.775 Gpnmb
glycoprotein (transmembrane) nmb
chr2_+_84574217 0.749 NM_001005342
Ypel4
yippee-like 4 (Drosophila)
chr5_-_74038829 0.735 NM_011890
Sgcb
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr2_+_134611953 0.716 Plcb1
phospholipase C, beta 1
chr16_-_85173978 0.711 App
amyloid beta (A4) precursor protein
chr9_+_44048756 0.684 NM_001081369
Ccdc153
coiled-coil domain containing 153
chr16_-_37384915 0.666 Stxbp5l
syntaxin binding protein 5-like
chr8_+_124805995 0.653 NM_009569
Zfpm1
zinc finger protein, multitype 1
chr3_+_90341208 0.651 S100a16
S100 calcium binding protein A16
chr13_+_30751950 0.647 NM_134068
NM_001037955
Dusp22

dual specificity phosphatase 22

chr6_+_29718515 0.646 Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr18_-_31606908 0.630 NM_009308
Syt4
synaptotagmin IV
chr3_+_89195758 0.627


chr2_+_25284190 0.619 NM_007379
Abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr6_+_124946723 0.614 NM_175696
C530028O21Rik
RIKEN cDNA C530028O21 gene
chr13_-_8870975 0.609 NM_001039388
Wdr37
WD repeat domain 37
chr2_+_68973856 0.605 NM_181547
Nostrin
nitric oxide synthase trafficker
chr9_+_106350967 0.598 NM_029631
Abhd14b
abhydrolase domain containing 14b
chr1_+_173367685 0.582 NM_172647
F11r
F11 receptor
chr10_+_93977597 0.577 NM_172051
Tmcc3
transmembrane and coiled coil domains 3
chr2_+_134611931 0.574 Plcb1
phospholipase C, beta 1
chr3_-_131006068 0.572 NM_027816
Cyp2u1
cytochrome P450, family 2, subfamily u, polypeptide 1
chr19_+_20567199 0.570 E030003E18Rik
RIKEN cDNA E030003E18 gene
chr11_-_83880574 0.569 Dusp14
dual specificity phosphatase 14
chr15_-_97597988 0.566 NM_001177810
NM_001177811
NM_144850
Rapgef3


Rap guanine nucleotide exchange factor (GEF) 3


chr11_-_98190774 0.563 NM_010895
Neurod2
neurogenic differentiation 2
chr11_+_97702591 0.558 B230217C12Rik
RIKEN cDNA B230217C12 gene
chr10_+_59740373 0.554 NM_001146120
NM_001146121
NM_001146122
NM_001146123
NM_011179
Psap




prosaposin




chr1_-_156731538 0.553 Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr9_+_60560923 0.549 NM_026235
Larp6
La ribonucleoprotein domain family, member 6
chr7_+_129776837 0.548 Prkcb
protein kinase C, beta
chr6_+_4455686 0.544 NM_007743
Col1a2
collagen, type I, alpha 2
chr11_-_51464287 0.543 N4bp3
NEDD4 binding protein 3
chr9_-_91260597 0.542 Zic1
zinc finger protein of the cerebellum 1
chr5_-_149363829 0.538 Ubl3
ubiquitin-like 3
chr1_+_75233201 0.531


chr5_-_63157309 0.518 NM_178407
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_-_149211354 0.516 NM_007513
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr3_-_87804277 0.502 NM_001109758
NM_007529
Bcan

brevican

chr8_-_63433528 0.498 NM_173876
Clcn3
chloride channel 3
chr10_+_115580947 0.496 Ptprr
protein tyrosine phosphatase, receptor type, R
chr12_-_103057259 0.487 NM_011812
Fbln5
fibulin 5
chr16_+_36935029 0.477 NM_008225
Hcls1
hematopoietic cell specific Lyn substrate 1
chr17_+_35400038 0.477 NM_010380
H2-D1
histocompatibility 2, D region locus 1
chr19_-_6235784 0.472 NM_198168
Ppp2r5b
protein phosphatase 2, regulatory subunit B (B56), beta isoform
chr6_-_97409251 0.472 Frmd4b
FERM domain containing 4B
chr3_+_31048841 0.472 NM_008770
Cldn11
claudin 11
chr7_+_16683891 0.469 NM_025898
Napa
N-ethylmaleimide sensitive fusion protein attachment protein alpha
chr16_-_4879787 0.465 NM_145359
Fam100a
family with sequence similarity 100, member A
chr7_-_91234908 0.463 NM_030728
9930013L23Rik
RIKEN cDNA 9930013L23 gene
chr2_+_167247181 0.463 NM_148929
NM_178371
Slc9a8

solute carrier family 9 (sodium/hydrogen exchanger), member 8

chr1_+_167391318 0.458 NM_027430
Brp44
brain protein 44
chr9_-_75257067 0.457 NM_027418
Mapk6
mitogen-activated protein kinase 6
chr11_-_60166321 0.455 Tom1l2
target of myb1-like 2 (chicken)
chr4_-_86876328 0.455 NM_172426
Slc24a2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr1_+_174078246 0.455 Dcaf8
DDB1 and CUL4 associated factor 8
chr17_+_35187185 0.450 NM_033444
Clic1
chloride intracellular channel 1
chr5_-_8367951 0.449 NM_001007220
NM_001007221
NM_001098225
Adam22


a disintegrin and metallopeptidase domain 22


chr9_+_57787915 0.448 NM_011352
Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr8_+_96696677 0.442 Mt2
metallothionein 2
chr1_+_174078297 0.439 Dcaf8
DDB1 and CUL4 associated factor 8
chr5_-_66155584 0.435 Gm5296
predicted gene 5296
chr12_+_112776311 0.432 NM_173363
NM_178041
Eif5

eukaryotic translation initiation factor 5

chr18_+_36441115 0.432 Pura
purine rich element binding protein A
chr18_-_35658485 0.425 NM_030749
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr3_+_95463691 0.424 Mcl1
myeloid cell leukemia sequence 1
chr1_-_172040852 0.423 Ddr2
discoidin domain receptor family, member 2
chr15_-_79518160 0.422 NM_028792
Josd1
Josephin domain containing 1
chr9_-_111592643 0.418 NM_016853
Stac
src homology three (SH3) and cysteine rich domain
chr4_-_155148591 0.417 NM_147776
Vwa1
von Willebrand factor A domain containing 1
chr19_+_5637459 0.417 NM_009045
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr15_-_34608600 0.416 Nipal2
NIPA-like domain containing 2
chr4_-_132768403 0.415 NM_008154
Gpr3
G-protein coupled receptor 3
chr16_-_85173851 0.413 App
amyloid beta (A4) precursor protein
chr19_-_6915038 0.410 NM_019924
Rps6ka4
ribosomal protein S6 kinase, polypeptide 4
chr8_-_86095743 0.408


chr1_+_75233046 0.406 Dnajb2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr6_+_29718490 0.405 Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr3_-_108029499 0.405 NM_008596
Sypl2
synaptophysin-like 2
chr11_+_78002249 0.402 NM_033475
Rab34
RAB34, member of RAS oncogene family
chr8_+_96910392 0.399 NM_022331
Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr3_-_84063605 0.398 Trim2
tripartite motif-containing 2
chr7_+_134985164 0.398 NM_009294
Stx4a
syntaxin 4A (placental)
chr7_+_52960702 0.398 Dbp
D site albumin promoter binding protein
chr18_+_61204798 0.394 NM_001146268
NM_008809
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr19_-_7557553 0.392 Rtn3
reticulon 3
chr6_+_48986501 0.389 NM_053110
Gpnmb
glycoprotein (transmembrane) nmb
chr10_+_41239248 0.388 NM_016898
Cd164
CD164 antigen
chr3_-_73512139 0.388 Bche
butyrylcholinesterase
chr18_+_36440748 0.387 NM_008989
Pura
purine rich element binding protein A
chr7_+_52882857 0.384 NM_028544
Rasip1
Ras interacting protein 1
chr15_+_82105322 0.384 NM_011889
Sept3
septin 3
chr7_-_31758390 0.380 NM_001164184
NM_001164185
NM_017405
Lsr


lipolysis stimulated lipoprotein receptor


chr18_+_12287232 0.377 NM_024182
Riok3
RIO kinase 3 (yeast)
chr7_+_134985435 0.377 Stx4a
syntaxin 4A (placental)
chr16_+_49911557 0.377 Cd47
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr2_+_25733302 0.376 NM_175462
Kcnt1
potassium channel, subfamily T, member 1
chr17_+_44090192 0.372 Rcan2
regulator of calcineurin 2
chr9_-_56265833 0.372 NM_172924
C230081A13Rik
RIKEN cDNA C230081A13 gene
chr10_-_77432541 0.370 NM_138301
Trpm2
transient receptor potential cation channel, subfamily M, member 2
chr19_+_5568045 0.370 NM_001033448
Gm962
predicted gene 962
chr7_-_133942605 0.370 NM_001177307
Aldoa
aldolase A, fructose-bisphosphate
chr11_+_20443315 0.368 Sertad2
SERTA domain containing 2
chr1_+_74331503 0.367 NM_001039509
NM_025580
Pnkd

paroxysmal nonkinesiogenic dyskinesia

chr13_-_19711409 0.364 NM_134065
Epdr1
ependymin related protein 1 (zebrafish)
chr11_+_115891591 0.360 NM_172569
Unk
unkempt homolog (Drosophila)
chr2_+_3630817 0.358 Fam107b
family with sequence similarity 107, member B
chr12_+_31950252 0.355 Lamb1
laminin B1
chr5_-_149364353 0.352 NM_011908
Ubl3
ubiquitin-like 3
chr11_-_68666432 0.350 Ndel1
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr9_-_112090150 0.347 NM_033264
NM_001177615
NM_001177620
NM_028755
Arpp21



cyclic AMP-regulated phosphoprotein, 21



chrX_-_7709452 0.346 Wdr13
WD repeat domain 13
chrX_-_71269083 0.343 Irak1
interleukin-1 receptor-associated kinase 1
chr1_-_22812829 0.341 Rims1
regulating synaptic membrane exocytosis 1
chr11_+_102964362 0.341 Acbd4
acyl-Coenzyme A binding domain containing 4
chr8_-_48374755 0.339 NM_001114311
Stox2
storkhead box 2
chr6_+_135312948 0.338 NM_010128
Emp1
epithelial membrane protein 1
chr1_+_174078258 0.338 Dcaf8
DDB1 and CUL4 associated factor 8
chr5_-_135223110 0.335 NM_007925
Eln
elastin
chr9_+_106124928 0.334 NM_031178
Tlr9
toll-like receptor 9
chr19_+_9004106 0.334 NM_144872
Eml3
echinoderm microtubule associated protein like 3
chr18_-_64676090 0.334 Nars
asparaginyl-tRNA synthetase
chr8_+_68141935 0.332 NM_001166372
March1
membrane-associated ring finger (C3HC4) 1
chr11_-_115138199 0.331 NM_007997
Fdxr
ferredoxin reductase
chr11_+_72115129 0.330 NM_001037713
Xaf1
XIAP associated factor 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment p-value GO term description
4.43 4.77e-03 GO:0044421 extracellular region part
2.25 1.98e-02 GO:0005886 plasma membrane
2.21 2.60e-02 GO:0071944 cell periphery

Nothing significant found in function category.