Motif ID: GATA1..3.p2

Z-value: 1.702

Transcription factors associated with GATA1..3.p2:

NameEntrezDescription
Gata1 14460 GATA binding protein 1
Gata2 14461 GATA binding protein 2
Gata3 14462 GATA binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Gata1chrX_-_7544940-0.633.2e-05Click!
Gata2chr6_+_88148657-0.626.0e-05Click!
Gata3chr2_-_9800211-0.572.5e-04Click!


Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr14_-_55735399 10.401 Jph4
junctophilin 4
chr9_-_29770699 9.958 NM_172290
Ntm
neurotrimin
chr11_-_98190774 9.917 NM_010895
Neurod2
neurogenic differentiation 2
chr11_+_87574041 9.055 NM_172449
Bzrap1
benzodiazepine receptor associated protein 1
chr4_+_97248556 8.461 NM_001122952
Nfia
D130039L10Rik
nuclear factor I/A
RIKEN cDNA D130039L10 gene
chr5_-_143666064 7.084 Actb
actin, beta
chr8_-_3624988 7.081 NM_001129804
Pcp2
Purkinje cell protein 2 (L7)
chr17_-_90487479 6.444 Nrxn1
neurexin I
chr6_-_55631085 6.095 Neurod6
neurogenic differentiation 6
chrX_+_10062237 5.876 NM_019634
Tspan7
tetraspanin 7
chr18_+_37999857 5.129


chr19_-_5801011 4.879 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr11_-_102758340 4.831 Gfap
glial fibrillary acidic protein
chr2_-_25325248 4.605 NM_008963
Ptgds
prostaglandin D2 synthase (brain)
chr6_-_55631039 4.554 Neurod6
neurogenic differentiation 6
chr2_+_158436493 4.508 NM_009508
Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr19_+_23833310 4.476 NM_177034
Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
chr14_-_55735114 4.425 NM_177049
Jph4
junctophilin 4
chr10_+_90039435 4.371 NM_001177396
NM_001177398
NM_181398
Ipw
Anks1b


imprinted gene in the Prader-Willi syndrome region
ankyrin repeat and sterile alpha motif domain containing 1B


chr17_-_91492065 4.280 NM_020252
NM_177284
Nrxn1

neurexin I

chr8_-_3625251 4.274 NM_008790
Pcp2
Purkinje cell protein 2 (L7)
chr2_+_61884596 4.229 NM_033552
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr19_+_4711207 4.158 Spnb3
spectrin beta 3
chr6_-_124414668 4.072 NM_153508
Clstn3
calsyntenin 3
chr5_-_143666425 4.028


chr19_+_45122281 3.865 Sfxn3
sideroflexin 3
chr15_+_82086506 3.853 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr15_+_91991704 3.828 NM_001159647
Cntn1
contactin 1
chr12_+_101444303 3.679 Calm1
calmodulin 1
chr15_-_48623520 3.392 NM_001081391
Csmd3
CUB and Sushi multiple domains 3
chrX_+_98494487 3.387 NM_172932
Nlgn3
neuroligin 3
chr1_-_137064124 3.359 NM_134438
Gpr37l1
G protein-coupled receptor 37-like 1
chr8_+_24780132 3.319 NM_177086
Zmat4
zinc finger, matrin type 4
chr4_+_9196439 3.316 NM_028940
Clvs1
clavesin 1
chr10_+_128370814 3.255 NM_008398
Itga7
integrin alpha 7
chrM_+_15355 3.255


chr11_+_78139476 3.190 Aldoc
aldolase C, fructose-bisphosphate
chr17_-_35971913 3.175 Tubb5
tubulin, beta 5
chr3_+_136598485 3.175 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr7_-_104566013 3.174 NM_009381
Thrsp
thyroid hormone responsive SPOT14 homolog (Rattus)
chr10_-_108447894 3.160 Syt1
synaptotagmin I
chr11_+_68902025 3.095 NM_009497
Vamp2
vesicle-associated membrane protein 2
chr4_+_129985957 3.070 NM_010174
Fabp3
fatty acid binding protein 3, muscle and heart
chr8_-_127093601 3.069 NM_007428
Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr18_+_69843730 3.060 Tcf4
transcription factor 4
chr10_+_126515962 3.048 NM_001033263
Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr11_-_102758460 3.047 NM_001131020
NM_010277
Gfap

glial fibrillary acidic protein

chr4_-_25726753 3.026 Fut9
fucosyltransferase 9
chr18_+_82723920 3.015 Mbp
myelin basic protein
chr14_+_19103655 2.986 NM_023526
Nkiras1
NFKB inhibitor interacting Ras-like protein 1
chr1_+_145487825 2.979 NM_020025
B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chrX_-_7709907 2.917 NM_026137
Wdr13
WD repeat domain 13
chr3_-_81878554 2.912 NM_001161796
NM_017469
Gucy1b3

guanylate cyclase 1, soluble, beta 3

chr17_+_37187984 2.887 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr3_+_136598184 2.881 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr12_+_110798661 2.872 Meg3
maternally expressed 3
chr11_-_75609557 2.855 NM_007873
Doc2b
double C2, beta
chr9_+_27598853 2.840 NM_177906
Opcml
opioid binding protein/cell adhesion molecule-like
chr11_-_58768012 2.833 NM_206882
Hist3h2bb-ps
histone cluster 3, H2bb, pseudogene
chr10_-_108447674 2.766 NM_009306
Syt1
synaptotagmin I
chr3_+_28162135 2.765 NM_001163007
NM_001163008
NM_001163009
NM_026910
Tnik



TRAF2 and NCK interacting kinase



chr1_-_164408123 2.760 Dnm3
dynamin 3
chr5_+_137506122 2.726 NM_001039385
Vgf
VGF nerve growth factor inducible
chr15_-_98781060 2.726 Tuba1a
tubulin, alpha 1A
chr8_-_124431581 2.721 NM_011404
Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr8_-_87296172 2.678 Nfix
nuclear factor I/X
chr9_+_68501551 2.672 NM_013646
Rora
RAR-related orphan receptor alpha
chr1_-_174228105 2.670 NM_178405
Atp1a2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr16_+_6349108 2.622 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr15_+_40486577 2.600 NM_011766
Zfpm2
zinc finger protein, multitype 2
chr15_-_8660462 2.592 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr19_-_19185685 2.588 NM_001043354
Rorb
RAR-related orphan receptor beta
chr13_+_83663817 2.580 Mef2c
myocyte enhancer factor 2C
chr1_+_160292665 2.561 Astn1
astrotactin 1
chr13_+_59234737 2.548 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr3_+_17954324 2.541 NM_021560
Bhlhe22
basic helix-loop-helix family, member e22
chr1_-_64167952 2.506 NM_033563
Klf7
Kruppel-like factor 7 (ubiquitous)
chr9_+_27106773 2.480 NM_001033323
NM_001129787
Igsf9b

immunoglobulin superfamily, member 9B

chr6_-_115201866 2.467 NM_080639
Timp4
tissue inhibitor of metalloproteinase 4
chr1_-_164408008 2.461 Dnm3
dynamin 3
chr3_+_96363312 2.452 Txnip
thioredoxin interacting protein
chr14_+_35124004 2.440 Glud1
glutamate dehydrogenase 1
chr14_+_63761085 2.421 Ctsb
cathepsin B
chr1_-_134603848 2.390 NM_001160318
Nfasc
neurofascin
chr10_+_4424140 2.375 NM_001161822
NM_019958
Rgs17

regulator of G-protein signaling 17

chr11_-_69419419 2.375 NM_013415
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chrM_+_3913 2.347


chr19_+_22522646 2.318 NM_177341
Trpm3
transient receptor potential cation channel, subfamily M, member 3
chr1_-_173152634 2.304 NM_001037170
Tomm40l
translocase of outer mitochondrial membrane 40 homolog-like (yeast)
chr13_-_100199745 2.281 Mtap1b
microtubule-associated protein 1B
chr18_+_82723907 2.271 Mbp
myelin basic protein
chr12_+_77505356 2.268 NM_008301
Hspa2
heat shock protein 2
chr14_-_55400722 2.264 NM_016972
Slc7a8
solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
chr6_+_124946723 2.257 NM_175696
C530028O21Rik
RIKEN cDNA C530028O21 gene
chr4_-_126430511 2.252 NM_011986
Ncdn
neurochondrin
chr10_-_18463500 2.251 NM_001033258
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr2_+_118605431 2.237 NM_170593
Disp2
dispatched homolog 2 (Drosophila)
chr1_+_187278726 2.234 NM_001033286
Slc30a10
solute carrier family 30, member 10
chr1_+_81073778 2.233 NM_172849
9430031J16Rik
RIKEN cDNA 9430031J16 gene
chr6_+_88674821 2.231 Mgll
monoglyceride lipase
chr8_-_70342105 2.224 NM_027626
Psd3
pleckstrin and Sec7 domain containing 3
chr6_-_115201846 2.208 Timp4
tissue inhibitor of metalloproteinase 4
chr10_-_108448003 2.205 Syt1
synaptotagmin I
chrX_-_7783571 2.201 NM_016913
NM_023638
NM_145907
NM_145908
Porcn



porcupine homolog (Drosophila)



chr2_-_24618566 2.176 NM_001042528
NM_007579
Cacna1b

calcium channel, voltage-dependent, N type, alpha 1B subunit

chr8_+_48072271 2.150 NM_177304
Enpp6
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr6_+_113232319 2.144 Cpne9
copine family member IX
chr2_-_25174498 2.139 Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr7_-_25790888 2.137 NM_144921
Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr7_+_134094045 2.135 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr3_+_117278144 2.135 NM_029425
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr10_+_80642285 2.092 Eef2
eukaryotic translation elongation factor 2
chr10_-_36855668 2.083 Marcks
myristoylated alanine rich protein kinase C substrate
chr5_-_21850490 2.049 NM_011261
Reln
reelin
chr7_+_133966816 2.049 NM_029978
Fam57b
family with sequence similarity 57, member B
chr1_-_173152548 2.039 Tomm40l
translocase of outer mitochondrial membrane 40 homolog-like (yeast)
chr1_-_164408133 2.035 NM_001038619
NM_172646
Dnm3

dynamin 3

chr11_-_99105293 2.023 NM_172946
Krt222
keratin 222
chr15_-_8660442 2.011 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrM_+_1091 2.003


chr17_+_35383898 2.000 Ddx39b
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr11_-_42134509 1.994 Gabra6
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6
chr5_+_22252006 1.972 NM_001081231
NM_029990
Lhfpl3

lipoma HMGIC fusion partner-like 3

chr3_+_45182311 1.962 NM_001098170
NM_001098171
NM_001098172
NM_011043
Pcdh10



protocadherin 10



chr19_+_8692485 1.955 NM_008766
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr1_+_179374783 1.938 NM_001012330
Zfp238
zinc finger protein 238
chr17_-_25073798 1.938 Mapk8ip3
mitogen-activated protein kinase 8 interacting protein 3
chr2_-_25174662 1.934 NM_001177656
NM_001177657
NM_008169
Grin1


glutamate receptor, ionotropic, NMDA1 (zeta 1)


chr19_-_5801766 1.924 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr16_-_95219189 1.923 NM_001025584
NM_001025585
NM_010606
Kcnj6


potassium inwardly-rectifying channel, subfamily J, member 6


chr10_-_127057998 1.921 Lrp1
low density lipoprotein receptor-related protein 1
chr6_-_113481340 1.915 Tmem111
transmembrane protein 111
chr4_-_82151004 1.915 Nfib
nuclear factor I/B
chr2_+_121115337 1.895 NM_032393
Mtap1a
microtubule-associated protein 1 A
chr7_-_25757587 1.890 NM_010261
Rabac1
Rab acceptor 1 (prenylated)
chr11_+_75546480 1.889 Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr9_+_95459990 1.884 NM_198414
Paqr9
progestin and adipoQ receptor family member IX
chr14_-_76956445 1.870 NM_001160326
Serp2
stress-associated endoplasmic reticulum protein family member 2
chr3_+_17954500 1.869 Bhlhe22
basic helix-loop-helix family, member e22
chr17_-_25073888 1.864 Mapk8ip3
mitogen-activated protein kinase 8 interacting protein 3
chr3_-_89049088 1.859 NM_001039466
Trim46
tripartite motif-containing 46
chrX_-_67618136 1.857 Ids
iduronate 2-sulfatase
chr2_+_174171525 1.851 Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr7_+_129432585 1.850 NM_008855
Prkcb
protein kinase C, beta
chr4_+_119487105 1.835 NM_010657
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr2_+_174170886 1.791 Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr10_+_59568976 1.770 NM_052994
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr10_+_80642896 1.768 Eef2
eukaryotic translation elongation factor 2
chr12_-_86492150 1.766 NM_146244
Rps6kl1
ribosomal protein S6 kinase-like 1
chr10_-_10802102 1.757 NM_001114333
NM_016976
Grm1

glutamate receptor, metabotropic 1

chr2_-_79296732 1.746 NM_010894
Neurod1
neurogenic differentiation 1
chr18_-_25912171 1.746 Celf4
CUGBP, Elav-like family member 4
chr10_+_79630579 1.740 NM_007705
Cirbp
cold inducible RNA binding protein
chr5_+_19413335 1.739 NM_001170745
NM_015823
Magi2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chr8_-_124431245 1.735 Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr4_+_15808409 1.735 NM_009788
Calb1
calbindin 1
chr9_-_60535274 1.719 NM_001146047
Lrrc49
leucine rich repeat containing 49
chr1_+_137043277 1.716 NM_026823
Arl8a
ADP-ribosylation factor-like 8A
chr12_-_87165448 1.716 NM_021446
0610007P14Rik
RIKEN cDNA 0610007P14 gene
chr9_-_91260619 1.698 NM_009573
Zic1
zinc finger protein of the cerebellum 1
chr17_+_31523178 1.691 NM_001163748
NM_008804
Pde9a

phosphodiesterase 9A

chr11_-_42134548 1.682 NM_001099641
NM_008068
Gabra6

gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6

chr8_-_34858230 1.662 2700090O03Rik
RIKEN cDNA 2700090O03 gene
chr17_+_88929523 1.657 Klraq1
KLRAQ motif containing 1
chr9_-_102256962 1.652 NM_001168296
NM_173447
Ephb1

Eph receptor B1

chr17_+_37210011 1.650 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr14_-_52532988 1.648 Ndrg2
N-myc downstream regulated gene 2
chr19_+_4711220 1.647 NM_021287
Spnb3
spectrin beta 3
chr17_-_35972184 1.626 Tubb5
tubulin, beta 5
chrX_+_45872593 1.614 NM_011228
Rab33a
RAB33A, member of RAS oncogene family
chr17_+_35400038 1.605 NM_010380
H2-D1
histocompatibility 2, D region locus 1
chr11_+_102994627 1.604 NM_001130516
NM_001130515
NM_027658
Hexim2


hexamthylene bis-acetamide inducible 2


chr7_-_90883999 1.600 NM_010551
Il16
interleukin 16
chr4_+_119486921 1.600 Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr18_-_61560053 1.594 NM_133249
Ppargc1b
peroxisome proliferative activated receptor, gamma, coactivator 1 beta
chr19_+_5493612 1.589 Cfl1
cofilin 1, non-muscle
chr11_+_6375032 1.587


chr7_+_53651811 1.572 NM_008421
NM_001112739
Kcnc1

potassium voltage gated channel, Shaw-related subfamily, member 1

chr5_-_136387191 1.570 Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr8_-_86095743 1.568


chr18_-_35374663 1.567 NM_178005
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr5_+_98609872 1.562 NM_029947
Prdm8
PR domain containing 8
chr1_+_32229571 1.551 NM_133235
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr2_+_65458814 1.549


chr9_+_27106856 1.544 Igsf9b
immunoglobulin superfamily, member 9B
chrX_+_133357268 1.542 NM_011123
Plp1
proteolipid protein (myelin) 1
chr7_+_134072351 1.539 NM_172747
Kctd13
potassium channel tetramerisation domain containing 13
chr2_+_28048592 1.537 NM_001038613
NM_001038614
Olfm1

olfactomedin 1

chr12_+_77182878 1.534 Syne2
synaptic nuclear envelope 2
chr2_+_177876635 1.523 NM_028806
Phactr3
phosphatase and actin regulator 3
chr2_+_164793796 1.513 Slc12a5
solute carrier family 12, member 5
chr10_-_108447996 1.510 Syt1
synaptotagmin I
chr11_-_116515361 1.504 Cygb
cytoglobin
chr11_+_98603186 1.497 NM_178060
Thra
thyroid hormone receptor alpha
chr2_-_29108440 1.492 6530402F18Rik
RIKEN cDNA 6530402F18 gene
chr16_+_41532938 1.491 Lsamp
limbic system-associated membrane protein
chr14_-_52533039 1.478 Ndrg2
N-myc downstream regulated gene 2
chr15_-_8660479 1.476 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr16_+_49911557 1.475 Cd47
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr7_+_107756604 1.472 Rab6
RAB6, member RAS oncogene family

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
3.85 8.85e-17 GO:0007399 nervous system development
2.32 1.08e-13 GO:0051179 localization
2.44 6.57e-13 GO:0051234 establishment of localization
2.45 7.67e-13 GO:0006810 transport
5.81 9.79e-12 GO:0007610 behavior
3.85 6.73e-11 GO:0022008 neurogenesis
2.42 8.78e-11 GO:0048731 system development
7.27 1.42e-10 GO:0031644 regulation of neurological system process
7.78 4.53e-10 GO:0050804 regulation of synaptic transmission
3.81 7.79e-10 GO:0048699 generation of neurons
2.17 1.25e-09 GO:0007275 multicellular organismal development
7.22 1.98e-09 GO:0051969 regulation of transmission of nerve impulse
2.09 2.60e-09 GO:0032502 developmental process
5.46 7.70e-09 GO:0019226 transmission of nerve impulse
5.46 7.70e-09 GO:0035637 multicellular organismal signaling
2.20 8.61e-09 GO:0048856 anatomical structure development
4.81 1.96e-08 GO:0007267 cell-cell signaling
4.19 4.35e-08 GO:0030182 neuron differentiation
3.45 6.03e-08 GO:0006811 ion transport
4.73 6.96e-08 GO:0044057 regulation of system process
5.79 1.32e-07 GO:0007268 synaptic transmission
4.58 1.42e-07 GO:0048666 neuron development
4.14 2.70e-07 GO:0030001 metal ion transport
3.79 4.98e-07 GO:0006812 cation transport
2.58 9.28e-07 GO:0023051 regulation of signaling
3.56 1.13e-06 GO:0007154 cell communication
2.28 1.60e-06 GO:0030154 cell differentiation
2.82 3.35e-06 GO:0010646 regulation of cell communication
38.78 3.74e-06 GO:0035235 ionotropic glutamate receptor signaling pathway
2.21 4.92e-06 GO:0048869 cellular developmental process
8.48 5.17e-06 GO:0003001 generation of a signal involved in cell-cell signaling
8.48 5.17e-06 GO:0023061 signal release
2.29 8.19e-06 GO:0065008 regulation of biological quality
2.81 9.62e-06 GO:0051641 cellular localization
3.02 1.13e-05 GO:0048468 cell development
3.01 1.28e-05 GO:0051649 establishment of localization in cell
7.11 1.32e-05 GO:0007626 locomotory behavior
1.28 1.58e-05 GO:0009987 cellular process
2.40 2.07e-05 GO:0051239 regulation of multicellular organismal process
3.38 2.37e-05 GO:0007155 cell adhesion
1.93 2.65e-05 GO:0048518 positive regulation of biological process
3.11 2.73e-05 GO:0051049 regulation of transport
3.35 2.83e-05 GO:0022610 biological adhesion
7.28 3.36e-05 GO:0007611 learning or memory
3.85 4.55e-05 GO:0007417 central nervous system development
6.85 7.00e-05 GO:0050890 cognition
1.60 8.64e-05 GO:0032501 multicellular organismal process
9.24 1.43e-04 GO:0048167 regulation of synaptic plasticity
3.74 1.54e-04 GO:0060341 regulation of cellular localization
5.04 1.61e-04 GO:0032940 secretion by cell
4.24 1.65e-04 GO:0031175 neuron projection development
3.50 2.57e-04 GO:0030030 cell projection organization
4.10 2.80e-04 GO:0007420 brain development
4.51 3.15e-04 GO:0045664 regulation of neuron differentiation
1.91 3.43e-04 GO:0048522 positive regulation of cellular process
2.96 3.87e-04 GO:0055085 transmembrane transport
1.36 4.26e-04 GO:0065007 biological regulation
4.10 5.67e-04 GO:0046903 secretion
7.82 7.07e-04 GO:0006836 neurotransmitter transport
17.78 9.36e-04 GO:0010970 microtubule-based transport
17.78 9.36e-04 GO:0030705 cytoskeleton-dependent intracellular transport
17.07 1.22e-03 GO:0007215 glutamate signaling pathway
10.16 1.28e-03 GO:0050808 synapse organization
5.31 1.34e-03 GO:0043062 extracellular structure organization
4.48 1.74e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
3.98 1.82e-03 GO:0034220 ion transmembrane transport
1.37 2.00e-03 GO:0050794 regulation of cellular process
1.36 2.15e-03 GO:0050789 regulation of biological process
11.31 2.90e-03 GO:0007269 neurotransmitter secretion
4.29 3.05e-03 GO:0048812 neuron projection morphogenesis
3.75 4.13e-03 GO:0050767 regulation of neurogenesis
3.75 4.13e-03 GO:0051046 regulation of secretion
3.55 4.54e-03 GO:0051960 regulation of nervous system development
5.02 6.25e-03 GO:0010975 regulation of neuron projection development
3.77 7.39e-03 GO:0015672 monovalent inorganic cation transport
2.35 7.93e-03 GO:0032879 regulation of localization
5.25 1.01e-02 GO:0006813 potassium ion transport
1.54 1.02e-02 GO:0023052 signaling
7.69 1.09e-02 GO:0007612 learning
3.29 1.27e-02 GO:0060284 regulation of cell development
7.49 1.33e-02 GO:0001505 regulation of neurotransmitter levels
3.40 1.49e-02 GO:0051050 positive regulation of transport
4.26 1.52e-02 GO:0007409 axonogenesis
1.93 1.79e-02 GO:0048513 organ development
23.70 2.04e-02 GO:0008088 axon cargo transport
2.76 2.16e-02 GO:0040011 locomotion
4.31 2.92e-02 GO:0031344 regulation of cell projection organization
3.55 2.96e-02 GO:0048858 cell projection morphogenesis
3.53 3.07e-02 GO:0000904 cell morphogenesis involved in differentiation
2.96 3.20e-02 GO:0050801 ion homeostasis
3.06 3.30e-02 GO:0006873 cellular ion homeostasis
9.92 3.39e-02 GO:0048168 regulation of neuronal synaptic plasticity
3.48 3.72e-02 GO:0032990 cell part morphogenesis
2.99 4.63e-02 GO:0055082 cellular chemical homeostasis
1.78 4.68e-02 GO:0071842 cellular component organization at cellular level
2.98 4.78e-02 GO:0007010 cytoskeleton organization

Gene overrepresentation in compartment category:

enrichment p-value GO term description
6.02 4.54e-21 GO:0043005 neuron projection
8.75 1.16e-18 GO:0030424 axon
5.82 1.23e-16 GO:0045202 synapse
3.79 7.81e-16 GO:0042995 cell projection
6.52 2.58e-14 GO:0044297 cell body
6.63 5.37e-14 GO:0043025 neuronal cell body
2.15 8.35e-14 GO:0071944 cell periphery
6.74 1.20e-12 GO:0030425 dendrite
2.07 1.07e-11 GO:0005886 plasma membrane
5.21 3.45e-11 GO:0044463 cell projection part
1.24 1.75e-10 GO:0005623 cell
1.24 1.75e-10 GO:0044464 cell part
1.53 6.29e-10 GO:0005737 cytoplasm
9.16 1.11e-09 GO:0033267 axon part
1.71 2.24e-09 GO:0044444 cytoplasmic part
5.34 2.32e-09 GO:0044456 synapse part
1.36 3.37e-08 GO:0044424 intracellular part
1.35 6.54e-08 GO:0005622 intracellular
1.45 6.67e-07 GO:0016020 membrane
1.39 1.01e-06 GO:0043226 organelle
1.39 1.59e-06 GO:0043229 intracellular organelle
2.23 3.91e-06 GO:0044459 plasma membrane part
2.80 8.86e-06 GO:0044430 cytoskeletal part
2.35 1.08e-05 GO:0005856 cytoskeleton
2.38 1.44e-04 GO:0000267 cell fraction
8.77 1.85e-04 GO:0043197 dendritic spine
8.53 2.33e-04 GO:0044309 neuron spine
2.55 2.61e-04 GO:0005626 insoluble fraction
1.36 2.95e-04 GO:0043227 membrane-bounded organelle
2.89 4.77e-04 GO:0005887 integral to plasma membrane
5.30 6.74e-04 GO:0045211 postsynaptic membrane
1.34 8.12e-04 GO:0043231 intracellular membrane-bounded organelle
3.82 1.18e-03 GO:0048471 perinuclear region of cytoplasm
2.73 1.29e-03 GO:0031226 intrinsic to plasma membrane
2.80 1.34e-03 GO:0030054 cell junction
6.47 2.40e-03 GO:0008021 synaptic vesicle
2.83 2.78e-03 GO:0015630 microtubule cytoskeleton
1.37 3.16e-03 GO:0044425 membrane part
2.02 3.70e-03 GO:0005829 cytosol
2.51 3.72e-03 GO:0031982 vesicle
2.57 3.75e-03 GO:0031410 cytoplasmic vesicle
1.41 3.91e-03 GO:0031224 intrinsic to membrane
6.86 4.86e-03 GO:0014069 postsynaptic density
3.77 5.28e-03 GO:0005874 microtubule
6.77 5.31e-03 GO:0030427 site of polarized growth
1.73 5.82e-03 GO:0043228 non-membrane-bounded organelle
1.73 5.82e-03 GO:0043232 intracellular non-membrane-bounded organelle
2.34 6.27e-03 GO:0005624 membrane fraction
4.87 9.39e-03 GO:0030136 clathrin-coated vesicle
12.26 1.07e-02 GO:0030672 synaptic vesicle membrane
1.39 1.10e-02 GO:0016021 integral to membrane
1.65 1.12e-02 GO:0043234 protein complex
11.47 1.49e-02 GO:0044304 main axon
1.49 1.82e-02 GO:0044446 intracellular organelle part
1.48 2.07e-02 GO:0044422 organelle part
2.18 2.20e-02 GO:0005794 Golgi apparatus
6.38 2.53e-02 GO:0043679 axon terminus
4.29 2.76e-02 GO:0030135 coated vesicle
6.15 3.21e-02 GO:0030426 growth cone
26.66 3.28e-02 GO:0061200 clathrin sculpted gamma-aminobutyric acid transport vesicle
26.66 3.28e-02 GO:0061202 clathrin sculpted gamma-aminobutyric acid transport vesicle membrane
5.93 4.03e-02 GO:0044306 neuron projection terminus
4.09 4.06e-02 GO:0031252 cell leading edge
2.55 4.28e-02 GO:0031988 membrane-bounded vesicle
71.09 4.43e-02 GO:0005955 calcineurin complex
71.09 4.43e-02 GO:0060077 inhibitory synapse
23.70 4.86e-02 GO:0060198 clathrin sculpted vesicle
1.52 4.99e-02 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

enrichment p-value GO term description
1.72 7.56e-10 GO:0005515 protein binding
3.08 7.28e-09 GO:0005215 transporter activity
3.52 7.59e-09 GO:0022891 substrate-specific transmembrane transporter activity
3.23 2.60e-08 GO:0022892 substrate-specific transporter activity
3.27 3.53e-08 GO:0022857 transmembrane transporter activity
3.61 5.05e-08 GO:0015075 ion transmembrane transporter activity
4.00 2.82e-07 GO:0008324 cation transmembrane transporter activity
1.32 5.80e-06 GO:0005488 binding
3.23 2.39e-04 GO:0008092 cytoskeletal protein binding
3.05 1.07e-03 GO:0019904 protein domain specific binding
3.51 1.22e-03 GO:0005216 ion channel activity
3.43 1.65e-03 GO:0022838 substrate-specific channel activity
3.72 2.01e-03 GO:0022804 active transmembrane transporter activity
3.33 2.54e-03 GO:0015267 channel activity
3.32 2.63e-03 GO:0022803 passive transmembrane transporter activity
3.84 2.68e-03 GO:0022836 gated channel activity
3.97 3.66e-03 GO:0005261 cation channel activity
7.90 7.70e-03 GO:0015171 amino acid transmembrane transporter activity
12.26 1.30e-02 GO:0008066 glutamate receptor activity
3.23 1.95e-02 GO:0016563 transcription activator activity
6.64 2.39e-02 GO:0005275 amine transmembrane transporter activity
4.89 2.70e-02 GO:0022843 voltage-gated cation channel activity
2.25 2.84e-02 GO:0019899 enzyme binding
10.46 2.87e-02 GO:0015179 L-amino acid transmembrane transporter activity
5.32 3.66e-02 GO:0015276 ligand-gated ion channel activity
5.32 3.66e-02 GO:0022834 ligand-gated channel activity