Motif ID: GTF2A1,2.p2

Z-value: 0.957

Transcription factors associated with GTF2A1,2.p2:

NameEntrezDescription
Gtf2a1 83602 general transcription factor II A, 1
Gtf2a2 235459 general transcription factor II A, 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Gtf2a2chr9_+_698603490.382.1e-02Click!
Gtf2a1chr12_-_92828018-0.289.3e-02Click!


Activity profile for motif GTF2A1,2.p2.

activity profile for motif GTF2A1,2.p2


Sorted Z-values histogram for motif GTF2A1,2.p2

Sorted Z-values for motif GTF2A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2A1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr2_-_25325248 6.855 NM_008963
Ptgds
prostaglandin D2 synthase (brain)
chr11_+_94797565 5.629 NM_007742
Col1a1
collagen, type I, alpha 1
chr1_-_75215798 5.539 NM_009447
Tuba4a
tubulin, alpha 4A
chr13_-_22133203 3.359 NM_175656
Hist1h4i
histone cluster 1, H4i
chr13_-_23790310 3.227 NM_178208
Hist1h4c
histone cluster 1, H4c
chr7_+_146574969 2.964 NM_001127363
NM_183144
Inpp5a

inositol polyphosphate-5-phosphatase A

chr14_+_122874598 2.924 NM_009574
Zic2
zinc finger protein of the cerebellum 2
chr14_+_48740583 2.705 Peli2
pellino 2
chr11_+_100436283 2.611 Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr14_+_48740495 2.323 NM_033602
Peli2
pellino 2
chr14_+_122874625 2.048 Zic2
zinc finger protein of the cerebellum 2
chr12_+_86814822 2.039 NM_010234
Fos
FBJ osteosarcoma oncogene
chr2_+_138104219 2.001 NM_145534
Btbd3
BTB (POZ) domain containing 3
chr8_-_87297283 1.958 Nfix
nuclear factor I/X
chr4_-_128798481 1.898 NM_010471
Hpca
hippocalcin
chr16_+_30599808 1.889 NM_177632
Fam43a
family with sequence similarity 43, member A
chr11_-_4847968 1.717 NM_010904
Nefh
neurofilament, heavy polypeptide
chr10_-_24919916 1.659 Akap7
A kinase (PRKA) anchor protein 7
chr3_+_90345082 1.625 NM_026416
S100a16
S100 calcium binding protein A16
chr16_-_85803343 1.572 Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr10_-_6979959 1.545 Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr2_-_73498303 1.505 NM_001166604
NM_175752
Chn1

chimerin (chimaerin) 1

chr5_-_125659422 1.484 NM_011424
Ncor2
nuclear receptor co-repressor 2
chr18_-_32109233 1.454 NM_001025381
Gpr17
G protein-coupled receptor 17
chr10_-_59414516 1.417 NM_029083
Ddit4
DNA-damage-inducible transcript 4
chr15_-_82075137 1.405 NM_025639
NM_178269
Cenpm

centromere protein M

chr1_-_191511950 1.390 NM_001081363
Cenpf
centromere protein F
chr12_+_81891479 1.370 NM_178682
4933426M11Rik
RIKEN cDNA 4933426M11 gene
chr17_+_23863280 1.361 NM_023058
Pkmyt1
protein kinase, membrane associated tyrosine/threonine 1
chr1_-_55283189 1.353 Rftn2
raftlin family member 2
chr4_-_128798939 1.344 NM_001130419
Hpca
hippocalcin
chr13_+_22127689 1.322 NM_175665
Hist1h2bk
histone cluster 1, H2bk
chr10_+_60638341 1.316 Tbata
thymus, brain and testes associated
chr9_+_56712850 1.311 NM_139001
Cspg4
chondroitin sulfate proteoglycan 4
chr9_+_50560862 1.310 NM_009964
Cryab
crystallin, alpha B
chr4_+_104829963 1.271 Ppap2b
phosphatidic acid phosphatase type 2B
chr10_-_61970481 1.251 NM_011157
Srgn
serglycin
chr11_-_4018706 1.242 NM_144520
Sec14l2
SEC14-like 2 (S. cerevisiae)
chr7_-_88851662 1.230 Homer2
homer homolog 2 (Drosophila)
chr1_+_174271397 1.215 Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr14_+_12386094 1.172 Ptprg
protein tyrosine phosphatase, receptor type, G
chr13_-_23837389 1.161 NM_175653
Hist1h3c
histone cluster 1, H3c
chr4_+_153516477 1.154 NM_021499
Wdr8
WD repeat domain 8
chr11_-_75236018 1.138 Serpinf1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr10_-_79783221 1.137 NM_025521
2310011J03Rik
RIKEN cDNA 2310011J03 gene
chr13_-_23775827 1.124 NM_178189
Hist1h2ac
histone cluster 1, H2ac
chr16_-_85803359 1.089 NM_009621
Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr1_-_134036041 1.060 NM_008795
Cdk18
cyclin-dependent kinase 18
chr11_+_88860710 1.050 NM_009546
Trim25
tripartite motif-containing 25
chr3_-_120965803 1.024 Tmem56
transmembrane protein 56
chr14_+_70945119 1.020 Reep4
receptor accessory protein 4
chr3_+_102538849 1.017 Tspan2
tetraspanin 2
chr7_+_119571219 0.995 NM_020606
Parva
parvin, alpha
chr2_+_164313584 0.984 NM_001048229
Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr8_-_70342105 0.980 NM_027626
Psd3
pleckstrin and Sec7 domain containing 3
chr6_-_51419893 0.969 Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr11_+_54128404 0.962 NM_001033599
Acsl6
acyl-CoA synthetase long-chain family member 6
chr2_-_148269170 0.957 NM_010740
Cd93
CD93 antigen
chr18_-_78320014 0.945 Slc14a1
solute carrier family 14 (urea transporter), member 1
chr7_-_53176582 0.930 NM_010129
Emp3
epithelial membrane protein 3
chr12_+_81891598 0.922 4933426M11Rik
RIKEN cDNA 4933426M11 gene
chr9_+_43851477 0.900 Thy1
thymus cell antigen 1, theta
chr8_+_59934719 0.890 NM_009136
Scrg1
scrapie responsive gene 1
chr9_+_50561121 0.888 Cryab
crystallin, alpha B
chr11_+_102110161 0.885 NM_153544
BC030867
cDNA sequence BC030867
chr12_+_70473032 0.870 NM_007481
Arf6
ADP-ribosylation factor 6
chr10_+_127452270 0.864 NM_008921
Prim1
DNA primase, p49 subunit
chr18_+_69753035 0.854 Tcf4
transcription factor 4
chr6_-_82724366 0.848 NM_013820
Hk2
hexokinase 2
chr19_-_6235784 0.844 NM_198168
Ppp2r5b
protein phosphatase 2, regulatory subunit B (B56), beta isoform
chr6_-_94650118 0.839 NM_008377
Lrig1
leucine-rich repeats and immunoglobulin-like domains 1
chr13_-_24853723 0.836 NM_020567
Gmnn
geminin
chr7_-_19857121 0.816 Vasp
vasodilator-stimulated phosphoprotein
chr10_+_56097078 0.815 NM_010288
Gja1
gap junction protein, alpha 1
chr9_+_56712829 0.808 Cspg4
chondroitin sulfate proteoglycan 4
chr4_+_104829951 0.799 NM_080555
Ppap2b
phosphatidic acid phosphatase type 2B
chr7_-_88851798 0.776 NM_001164086
NM_011983
Homer2

homer homolog 2 (Drosophila)

chr13_+_21903614 0.773 NM_001195421
NM_175657
Hist1h4m
Hist1h4f
Hist1h4n
histone cluster 1, H4m
histone cluster 1, H4f
histone cluster 1, H4n
chr2_+_150735306 0.772 NM_001163476
NM_027014
Gins1

GINS complex subunit 1 (Psf1 homolog)

chr9_+_50561092 0.769 Cryab
crystallin, alpha B
chr11_-_107331865 0.768 NM_145823
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr4_-_153349097 0.764 NM_007859
Dffb
DNA fragmentation factor, beta subunit
chr2_+_156665812 0.763 NM_173396
Tgif2
TGFB-induced factor homeobox 2
chr10_+_79389816 0.760 NM_007880
Arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr4_+_147534776 0.757 NM_176848
Fbxo2
F-box protein 2
chr13_+_21813912 0.748 NM_178200
Hist1h2bm
histone cluster 1, H2bm
chr11_-_115992196 0.748 NM_178802
Trim65
tripartite motif-containing 65
chr15_+_102126686 0.747 NM_001014976
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr3_-_87067445 0.744 NM_030707
Fcrls
Fc receptor-like S, scavenger receptor
chr4_+_135502353 0.743 NM_008254
Hmgcl
3-hydroxy-3-methylglutaryl-Coenzyme A lyase
chr11_+_120645722 0.728 NM_145370
Gps1
G protein pathway suppressor 1
chr6_+_121160693 0.728 NM_017379
Tuba8
tubulin, alpha 8
chr14_+_55555300 0.725 NM_026066
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr5_-_115119973 0.723 Gltp
glycolipid transfer protein
chr1_+_36364557 0.722 NM_001172205
NM_001172206
NM_145996
Arid5a


AT rich interactive domain 5A (MRF1-like)


chr5_-_138613028 0.717 NM_008568
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr5_+_32438219 0.708 Fosl2
fos-like antigen 2
chr6_+_133985717 0.702 NM_007961
Etv6
ets variant gene 6 (TEL oncogene)
chr3_+_126300163 0.701 Camk2d
calcium/calmodulin-dependent protein kinase II, delta
chr10_-_80813067 0.699 NM_001163165
NM_010440
Hmg20b

high mobility group 20 B

chr4_+_84851330 0.697 NM_019535
Sh3gl2
SH3-domain GRB2-like 2
chr6_-_124861656 0.693 NM_008479
Lag3
lymphocyte-activation gene 3
chr2_-_173102033 0.685 NM_022995
Pmepa1
prostate transmembrane protein, androgen induced 1
chr2_-_151805846 0.684 Fam110a
family with sequence similarity 110, member A
chr1_+_95582188 0.683 NM_016778
Bok
BCL2-related ovarian killer protein
chr13_-_23654226 0.679 NM_178205
Hist1h3e
histone cluster 1, H3e
chr10_+_85763267 0.677 Timp3
tissue inhibitor of metalloproteinase 3
chr11_+_105829223 0.670 NM_207624
Ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr10_-_128063522 0.666 NM_013765
Rps26
ribosomal protein S26
chr15_-_8660729 0.660 NM_148938
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_82074765 0.653 NM_001080158
Cenpm
centromere protein M
chr2_-_144096164 0.651 Snx5
sorting nexin 5
chr15_-_8660393 0.646 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr16_-_29378636 0.644 NM_175650
Atp13a5
ATPase type 13A5
chr7_+_71537652 0.633 NM_028626
Mcee
methylmalonyl CoA epimerase
chr7_-_19856882 0.633 Vasp
vasodilator-stimulated phosphoprotein
chr18_+_23468655 0.628 Dtna
dystrobrevin alpha
chr9_+_110435100 0.622 NM_001081340
Setd2
SET domain containing 2
chr2_+_164793698 0.621 Slc12a5
solute carrier family 12, member 5
chr1_+_174271338 0.621 NM_001039484
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr9_+_20820403 0.607 NM_010493
Icam1
intercellular adhesion molecule 1
chr11_-_83391984 0.593 Ccl9
chemokine (C-C motif) ligand 9
chr11_+_4118227 0.589 NM_028022
Gatsl3
GATS protein-like 3
chr13_+_23625779 0.589 NM_175661
Hist1h2af
histone cluster 1, H2af
chr15_+_61817102 0.588 Myc
myelocytomatosis oncogene
chr2_+_25227840 0.587 NM_001081085
2010317E24Rik
RIKEN cDNA 2010317E24 gene
chr5_-_139470895 0.586 NM_008808
Pdgfa
platelet derived growth factor, alpha
chrX_+_7455387 0.583 NM_138606
Pim2
proviral integration site 2
chr9_+_72286335 0.583 NM_008613
Mns1
meiosis-specific nuclear structural protein 1
chr5_+_115777174 0.578 NM_025573
Srsf9
serine/arginine-rich splicing factor 9
chr6_+_125299717 0.576 NM_011609
Tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
chr4_+_84851440 0.569 Sh3gl2
SH3-domain GRB2-like 2
chr10_-_80813198 0.558 NM_001163166
Hmg20b
high mobility group 20 B
chr16_-_23127779 0.557 NM_145480
Rfc4
replication factor C (activator 1) 4
chr7_+_28233013 0.556 Blvrb
biliverdin reductase B (flavin reductase (NADPH))
chrX_+_7215705 0.553 NM_009305
Syp
synaptophysin
chr16_+_97578333 0.553 NM_019517
Bace2
beta-site APP-cleaving enzyme 2
chr10_+_62706600 0.547 NM_026101
Herc4
hect domain and RLD 4
chr3_+_90417072 0.546 S100a6
S100 calcium binding protein A6 (calcyclin)
chr1_-_175266945 0.543 Cadm3
cell adhesion molecule 3
chr4_+_104830022 0.539 Ppap2b
phosphatidic acid phosphatase type 2B
chr17_-_35299913 0.538 Prrc2a
proline-rich coiled-coil 2A
chr4_+_147534729 0.537 Fbxo2
F-box protein 2
chr1_+_159388702 0.537 NM_001033284
BC026585
cDNA sequence BC026585
chr19_-_45824047 0.534 NM_008723
Npm3
nucleoplasmin 3
chr5_+_52755183 0.527 Sod3
superoxide dismutase 3, extracellular
chr3_-_100773571 0.522 NM_001013026
Ttf2
transcription termination factor, RNA polymerase II
chr19_-_4269161 0.511 NM_198113
Ssh3
slingshot homolog 3 (Drosophila)
chr14_-_69903072 0.508 NM_026331
Slc25a37
solute carrier family 25, member 37
chr8_+_86939262 0.507 NM_007578
Cacna1a
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr13_+_37437194 0.506 NM_010745
Ly86
lymphocyte antigen 86
chr14_-_52532988 0.506 Ndrg2
N-myc downstream regulated gene 2
chr3_+_157610182 0.502 NM_001013806
Ankrd13c
ankyrin repeat domain 13c
chr2_+_131012677 0.502 NM_001111075
NM_023117
Cdc25b

cell division cycle 25 homolog B (S. pombe)

chr17_-_33918382 0.498 Angptl4
angiopoietin-like 4
chr8_-_48760182 0.496 Ing2
inhibitor of growth family, member 2
chr5_+_144165482 0.491 NM_025841
Kdelr2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr8_-_113917651 0.485 NM_178086
Fa2h
fatty acid 2-hydroxylase
chr9_-_43921555 0.480 Rnf26
ring finger protein 26
chr8_-_48760457 0.479 NM_023503
Ing2
inhibitor of growth family, member 2
chr5_+_37633317 0.478 NM_001136058
Crmp1
collapsin response mediator protein 1
chr5_+_115791215 0.477 NM_026933
Triap1
TP53 regulated inhibitor of apoptosis 1
chr7_-_52359079 0.476 NM_010189
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr19_-_23522811 0.476 NM_174857
Mamdc2
MAM domain containing 2
chr9_+_50561315 0.472 Cryab
crystallin, alpha B
chr8_-_11312729 0.466 NM_009931
Col4a1
collagen, type IV, alpha 1
chr6_+_88852321 0.466 Tpra1
transmembrane protein, adipocyte asscociated 1
chr15_+_100766701 0.463 NM_011323
Scn8a
sodium channel, voltage-gated, type VIII, alpha
chr15_-_66801198 0.462 NM_008681
Ndrg1
N-myc downstream regulated gene 1
chrM_-_622 0.454


chr11_-_98190774 0.453 NM_010895
Neurod2
neurogenic differentiation 2
chr9_-_70504934 0.451 NM_172772
Fam63b
family with sequence similarity 63, member B
chr11_+_16951911 0.440 NM_029861
Cnrip1
cannabinoid receptor interacting protein 1
chr2_+_164793796 0.433 Slc12a5
solute carrier family 12, member 5
chr2_+_164595389 0.432 Ube2c
ubiquitin-conjugating enzyme E2C
chr11_+_116938095 0.430 2810008D09Rik
RIKEN cDNA 2810008D09 gene
chr4_+_40216581 0.429 2010003O02Rik
RIKEN cDNA 2010003O02 gene
chr4_+_52452089 0.428 NM_008017
Smc2
structural maintenance of chromosomes 2
chr3_+_87946259 0.428 NM_133665
Mef2d
myocyte enhancer factor 2D
chr11_-_69734838 0.428 NM_001166589
NM_001166591
NM_181582
Eif5a


eukaryotic translation initiation factor 5A


chr2_+_174167321 0.427


chr13_+_75977323 0.426 NM_053108
Glrx
glutaredoxin
chr9_+_66561492 0.424 NM_178396
Car12
carbonic anyhydrase 12
chr13_+_96095231 0.424 Zbed3
zinc finger, BED domain containing 3
chr7_-_125676823 0.422 NM_009940
Coq7
demethyl-Q 7
chr11_+_59661532 0.422 NM_134029
Nt5m
5',3'-nucleotidase, mitochondrial
chr7_+_25378887 0.419 Ethe1
ethylmalonic encephalopathy 1
chr13_-_21924019 0.418 NM_175657
Hist1h4f
Hist1h4n
histone cluster 1, H4f
histone cluster 1, H4n
chr13_-_58375469 0.413 NM_019832
Gkap1
G kinase anchoring protein 1
chr4_-_109339239 0.412 Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr3_-_57379600 0.410 NM_133784
Wwtr1
WW domain containing transcription regulator 1
chr12_-_88067400 0.410 NM_144524
Angel1
angel homolog 1 (Drosophila)
chr11_+_100436316 0.407 Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr3_+_94758056 0.407 Rfx5
regulatory factor X, 5 (influences HLA class II expression)
chr1_-_121401236 0.405 NM_022327
Ralb
v-ral simian leukemia viral oncogene homolog B (ras related)
chr18_-_10182019 0.404 Rock1
Rho-associated coiled-coil containing protein kinase 1
chr13_+_23776066 0.399 NM_023422
Hist1h2bc
histone cluster 1, H2bc
chr1_-_36766756 0.397 NM_146107
Actr1b
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr5_+_32438843 0.396 NM_008037
Fosl2
fos-like antigen 2
chr11_-_17111513 0.394 Pno1
partner of NOB1 homolog (S. cerevisiae)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.