Motif ID: GTF2I.p2

Z-value: 1.771

Transcription factors associated with GTF2I.p2:

NameEntrezDescription
Gtf2i 14886 general transcription factor II I

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Gtf2ichr5_-_134790544-0.547.0e-04Click!


Activity profile for motif GTF2I.p2.

activity profile for motif GTF2I.p2


Sorted Z-values histogram for motif GTF2I.p2

Sorted Z-values for motif GTF2I.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2I.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr14_-_55735399 13.176 Jph4
junctophilin 4
chr11_+_69831951 8.635 NM_001109752
NM_007864
Dlg4

discs, large homolog 4 (Drosophila)

chr3_-_143865162 7.733 NM_001161770
NM_001161769
Lmo4

LIM domain only 4

chr11_-_74537303 7.542 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr9_+_69137694 7.399 Rora
RAR-related orphan receptor alpha
chr7_-_25790888 7.399 NM_144921
Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr7_-_134968017 7.367 NM_024414
Stx1b
syntaxin 1B
chr7_+_133966816 6.263 NM_029978
Fam57b
family with sequence similarity 57, member B
chrX_-_69901382 6.219 NM_008067
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr11_-_98190774 6.184 NM_010895
Neurod2
neurogenic differentiation 2
chr7_+_134094045 5.987 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr1_-_64167952 5.906 NM_033563
Klf7
Kruppel-like factor 7 (ubiquitous)
chr9_+_68501551 5.888 NM_013646
Rora
RAR-related orphan receptor alpha
chr7_+_53040723 5.803 Lmtk3
lemur tyrosine kinase 3
chr17_+_37182910 5.599 NM_019439
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr6_+_110595574 5.568 Grm7
glutamate receptor, metabotropic 7
chr5_+_37637027 5.381 NM_007765
Crmp1
collapsin response mediator protein 1
chr4_-_82151657 5.280 Nfib
nuclear factor I/B
chr5_+_37259780 4.996 NM_172994
Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr8_+_65430028 4.954 NM_023689
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr17_+_37182986 4.921 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr7_+_64846528 4.880 NM_008071
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr9_-_56483379 4.872 Lingo1
leucine rich repeat and Ig domain containing 1
chr19_-_19185685 4.806 NM_001043354
Rorb
RAR-related orphan receptor beta
chr6_-_136123091 4.674 Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr9_+_43851477 4.672 Thy1
thymus cell antigen 1, theta
chr7_-_17200285 4.664 NM_172739
Grlf1
glucocorticoid receptor DNA binding factor 1
chr4_-_82151180 4.577 NM_001113209
NM_001113210
NM_008687
Nfib


nuclear factor I/B


chr19_+_6497834 4.569


chr14_-_55735114 4.537 NM_177049
Jph4
junctophilin 4
chr5_+_58109278 4.535 Pcdh7
protocadherin 7
chr13_+_42804911 4.459 NM_001005740
Phactr1
phosphatase and actin regulator 1
chr4_-_82151004 4.424 Nfib
nuclear factor I/B
chr16_-_42340613 4.416 NM_008083
Gap43
growth associated protein 43
chr6_-_124813720 4.415 Gpr162
G protein-coupled receptor 162
chr8_+_115093942 4.402 NM_130457
Cntnap4
contactin associated protein-like 4
chr4_+_97248556 4.391 NM_001122952
Nfia
D130039L10Rik
nuclear factor I/A
RIKEN cDNA D130039L10 gene
chr9_+_27598853 4.383 NM_177906
Opcml
opioid binding protein/cell adhesion molecule-like
chr6_-_124813922 4.361 NM_013533
Gpr162
G protein-coupled receptor 162
chr13_-_46060354 4.290 Atxn1
ataxin 1
chrX_-_133403050 4.285 NM_176971
Rab9b
RAB9B, member RAS oncogene family
chr6_-_124813970 4.244 Gpr162
G protein-coupled receptor 162
chr1_-_166387998 4.226 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr10_+_13685882 4.168 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr7_-_85722668 4.058 NM_008746
NM_182809
Ntrk3

neurotrophic tyrosine kinase, receptor, type 3

chr18_-_33623273 4.021 D0H4S114
DNA segment, human D4S114
chr10_+_13685579 3.990 2900084C01Rik
RIKEN cDNA 2900084C01 gene
chr4_+_132567420 3.980 NM_146155
Ahdc1
AT hook, DNA binding motif, containing 1
chr11_-_102157904 3.901 NM_001098836
NM_001098837
Atxn7l3

ataxin 7-like 3

chr2_-_180891448 3.890 Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr6_-_77929543 3.860 Ctnna2
catenin (cadherin associated protein), alpha 2
chr3_+_45182311 3.841 NM_001098170
NM_001098171
NM_001098172
NM_011043
Pcdh10



protocadherin 10



chr1_+_81073778 3.828 NM_172849
9430031J16Rik
RIKEN cDNA 9430031J16 gene
chr11_+_94871643 3.816 Samd14
sterile alpha motif domain containing 14
chr7_-_25857275 3.781 NM_008168
Grik5
glutamate receptor, ionotropic, kainate 5 (gamma 2)
chr2_+_121184334 3.700 NM_009897
Ckmt1
creatine kinase, mitochondrial 1, ubiquitous
chr11_-_116515361 3.678 Cygb
cytoglobin
chr10_+_4424140 3.675 NM_001161822
NM_019958
Rgs17

regulator of G-protein signaling 17

chr11_+_98603186 3.674 NM_178060
Thra
thyroid hormone receptor alpha
chr13_+_54472833 3.615 Cplx2
complexin 2
chr1_-_64167818 3.607 Klf7
Kruppel-like factor 7 (ubiquitous)
chr18_+_38115192 3.596 NM_153793
Rell2
RELT-like 2
chr4_+_155108890 3.537 NM_001101506
Gm5151
predicted gene 5151
chr3_-_143868114 3.523 Lmo4
LIM domain only 4
chr8_-_87461251 3.455 NM_019945
Mast1
microtubule associated serine/threonine kinase 1
chr9_-_86775282 3.397 Snap91
synaptosomal-associated protein 91
chr2_-_181048957 3.349 Stmn3
stathmin-like 3
chr3_+_28162135 3.345 NM_001163007
NM_001163008
NM_001163009
NM_026910
Tnik



TRAF2 and NCK interacting kinase



chr10_-_6979959 3.316 Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr6_-_77929685 3.289 Ctnna2
catenin (cadherin associated protein), alpha 2
chr7_+_120351012 3.275 Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr11_-_69651218 3.267 Nlgn2
neuroligin 2
chr2_+_90725895 3.259 NM_026161
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr6_+_114232767 3.244 Slc6a1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr15_+_40486577 3.219 NM_011766
Zfpm2
zinc finger protein, multitype 2
chr13_+_118391270 3.210 Hcn1
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr1_+_160292665 3.209 Astn1
astrotactin 1
chr6_-_113841295 3.141 Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr15_-_90509751 3.135 NM_001033851
NM_025815
Cpne8

copine VIII

chr1_-_175297778 3.125 NM_053199
Cadm3
cell adhesion molecule 3
chr7_+_52955153 3.112 NM_009800
Car11
carbonic anhydrase 11
chr18_-_43059156 3.058 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr3_-_80606598 3.035 Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2)
chrX_+_117403867 3.022 NM_001081385
Pcdh11x
protocadherin 11 X-linked
chr10_-_108447674 3.000 NM_009306
Syt1
synaptotagmin I
chr12_-_73509668 2.995 Rtn1
reticulon 1
chr6_-_124867962 2.973 NM_026988
Ptms
parathymosin
chr13_-_46060325 2.963 NM_009124
Atxn1
ataxin 1
chr9_-_91260619 2.949 NM_009573
Zic1
zinc finger protein of the cerebellum 1
chr7_+_152024499 2.941 NM_008007
Fgf3
fibroblast growth factor 3
chr5_+_37259906 2.929 Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr10_+_128346900 2.904 NM_007653
Cd63
CD63 antigen
chrX_+_158154967 2.896 NM_001103367
Rai2
retinoic acid induced 2
chr1_-_135817945 2.893 NM_054077
Prelp
proline arginine-rich end leucine-rich repeat
chr2_-_71205587 2.884 NM_172436
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr18_-_33623287 2.880 NM_053078
D0H4S114
DNA segment, human D4S114
chr14_+_67530044 2.843 NM_175498
Pnma2
paraneoplastic antigen MA2
chr5_-_9725274 2.840 NM_181850
Grm3
glutamate receptor, metabotropic 3
chr19_+_6418737 2.837 Nrxn2
neurexin II
chr5_+_43625165 2.818 Cpeb2
cytoplasmic polyadenylation element binding protein 2
chr16_+_38089536 2.801 Gsk3b
glycogen synthase kinase 3 beta
chr2_+_16277963 2.793 Plxdc2
plexin domain containing 2
chr18_+_33098914 2.786 Camk4
calcium/calmodulin-dependent protein kinase IV
chr6_-_77929660 2.779 NM_001109764
NM_009819
NM_145732
Ctnna2


catenin (cadherin associated protein), alpha 2


chr7_-_54387695 2.744 Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr11_+_98603041 2.739 Thra
thyroid hormone receptor alpha
chr17_-_91492065 2.729 NM_020252
NM_177284
Nrxn1

neurexin I

chr17_+_79451501 2.715 Qpct
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chr11_-_30168153 2.713 Spnb2
spectrin beta 2
chr6_-_32538191 2.708 NM_175750
Plxna4
plexin A4
chr3_+_136333083 2.700 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr17_+_37187550 2.686 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr18_+_36441115 2.662 Pura
purine rich element binding protein A
chr6_+_147995935 2.638 NM_178797
Far2
fatty acyl CoA reductase 2
chr2_+_140221165 2.637 NM_001013802
NM_028387
Macrod2

MACRO domain containing 2

chr9_+_64233432 2.635 NM_001134399
NM_172522
Megf11

multiple EGF-like-domains 11

chr17_-_90855291 2.626


chr12_-_5382487 2.624 NM_001164493
Klhl29
kelch-like 29 (Drosophila)
chr5_+_27588462 2.623 NM_001136060
Dpp6
dipeptidylpeptidase 6
chr12_+_89961317 2.599 NM_001198587
Nrxn3
neurexin III
chr4_-_25726753 2.594 Fut9
fucosyltransferase 9
chr11_+_75007300 2.581 Rtn4rl1
reticulon 4 receptor-like 1
chr2_+_55289530 2.572 NM_008426
Kcnj3
potassium inwardly-rectifying channel, subfamily J, member 3
chr3_-_108339375 2.554 NM_001033304
5330417C22Rik
RIKEN cDNA 5330417C22 gene
chr15_-_102347249 2.526 Map3k12
mitogen-activated protein kinase kinase kinase 12
chr8_-_3625251 2.519 NM_008790
Pcp2
Purkinje cell protein 2 (L7)
chr10_-_108448003 2.517 Syt1
synaptotagmin I
chr8_+_96334879 2.506 Gnao1
guanine nucleotide binding protein, alpha O
chr7_+_29236897 2.497 NM_030562
Lrfn1
leucine rich repeat and fibronectin type III domain containing 1
chr14_-_55531726 2.480 NM_021551
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr2_+_136539202 2.473 Snap25
synaptosomal-associated protein 25
chr18_+_36440748 2.469 NM_008989
Pura
purine rich element binding protein A
chr3_+_156224757 2.467 NM_001039094
NM_177274
Negr1

neuronal growth regulator 1

chr17_-_66426361 2.463 NM_001025572
Ankrd12
ankyrin repeat domain 12
chr6_-_124867732 2.462


chr7_-_52622167 2.416 Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr1_-_137482259 2.408 Nav1
neuron navigator 1
chr10_-_127057998 2.403 Lrp1
low density lipoprotein receptor-related protein 1
chrX_-_92391841 2.399 Arhgef9
CDC42 guanine nucleotide exchange factor (GEF) 9
chr16_-_20621287 2.381 NM_028420
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr11_-_118770859 2.377 Rbfox3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr2_+_158436493 2.375 NM_009508
Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr15_+_40486630 2.371 Zfpm2
zinc finger protein, multitype 2
chr11_-_74537778 2.370 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr5_+_81449776 2.367 Lphn3
latrophilin 3
chr13_+_54472806 2.358 Cplx2
complexin 2
chrX_-_98615096 2.351 NM_001177985
NM_001177986
Zmym3

zinc finger, MYM-type 3

chr7_-_25772525 2.329 Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr3_+_55046447 2.328 NM_001111053
NM_001195538
NM_019978
Dclk1


doublecortin-like kinase 1


chr1_+_154802144 2.313 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr5_-_121161656 2.287 NM_008052
Dtx1
deltex 1 homolog (Drosophila)
chr2_-_6805937 2.286 NM_001110228
NM_001160293
NM_010160
Celf2


CUGBP, Elav-like family member 2


chr6_+_124959207 2.263 Zfp384
zinc finger protein 384
chr3_-_89049088 2.261 NM_001039466
Trim46
tripartite motif-containing 46
chr2_+_37372112 2.260 NM_177383
Gpr21
G protein-coupled receptor 21
chr4_-_82151590 2.256 Nfib
nuclear factor I/B
chr2_-_79296732 2.242 NM_010894
Neurod1
neurogenic differentiation 1
chr7_+_53651811 2.219 NM_008421
NM_001112739
Kcnc1

potassium voltage gated channel, Shaw-related subfamily, member 1

chr4_+_73659506 2.214 NM_001163732
NM_172869
Frmd3

FERM domain containing 3

chr11_+_70658261 2.200 NM_019400
Rabep1
rabaptin, RAB GTPase binding effector protein 1
chr8_-_87461220 2.188 Mast1
microtubule associated serine/threonine kinase 1
chr5_-_100467945 2.180 Hnrpdl
heterogeneous nuclear ribonucleoprotein D-like
chr15_+_83998239 2.164 NM_054088
Pnpla3
patatin-like phospholipase domain containing 3
chr7_-_134170532 2.163 Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr14_+_122874625 2.158 Zic2
zinc finger protein of the cerebellum 2
chr7_-_134164627 2.158 NM_001102563
Prrt2
proline-rich transmembrane protein 2
chr15_-_25343483 2.154 NM_027395
Basp1
brain abundant, membrane attached signal protein 1
chr16_+_81200971 2.153 Ncam2
neural cell adhesion molecule 2
chr5_-_135223110 2.138 NM_007925
Eln
elastin
chr3_+_126299858 2.137 NM_001025438
NM_001025439
NM_023813
Camk2d


calcium/calmodulin-dependent protein kinase II, delta


chr3_+_55046548 2.107 Dclk1
doublecortin-like kinase 1
chrX_-_35605544 2.106 Fam70a
family with sequence similarity 70, member A
chr1_+_154802091 2.098 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr19_+_27292039 2.096 Vldlr
very low density lipoprotein receptor
chr14_+_122874598 2.082 NM_009574
Zic2
zinc finger protein of the cerebellum 2
chr6_-_56312170 2.079 NM_001025568
NM_001159952
NM_001159953
NM_011054
Pde1c



phosphodiesterase 1C



chr15_-_97662101 2.070 NM_019572
Hdac7
histone deacetylase 7
chr7_-_31836457 2.070 NM_022007
Fxyd7
FXYD domain-containing ion transport regulator 7
chr19_+_6418755 2.037 Nrxn2
neurexin II
chr3_+_125106995 2.024 NM_022565
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr3_+_75361454 2.023 NM_009250
Serpini1
serine (or cysteine) peptidase inhibitor, clade I, member 1
chr12_-_11443284 2.021 NM_012038
Vsnl1
visinin-like 1
chr12_+_3806955 2.021 NM_007872
Dnmt3a
DNA methyltransferase 3A
chr1_-_174259356 2.018 NM_008429
Kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr17_-_45823145 2.016 NM_198167
Tmem63b
transmembrane protein 63b
chr14_-_30534966 2.011 NM_009785
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr10_+_126515962 2.010 NM_001033263
Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr2_-_12933305 2.001 C1ql3
C1q-like 3
chr15_+_91881593 1.998 NM_001159648
Cntn1
contactin 1
chr11_-_61267383 1.978 NM_009548
Rnf112
ring finger protein 112
chr19_+_45063750 1.978 NM_011976
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr15_-_56526052 1.974 NM_008216
Has2
hyaluronan synthase 2
chr5_+_150214363 1.957 NM_027519
6330406I15Rik
RIKEN cDNA 6330406I15 gene
chrX_+_70748418 1.951 NM_177236
Atp2b3
ATPase, Ca++ transporting, plasma membrane 3
chr11_+_56825307 1.951 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr2_+_136539143 1.951 NM_011428
Snap25
synaptosomal-associated protein 25
chr10_-_128082881 1.948 NM_011772
Ikzf4
IKAROS family zinc finger 4
chr4_+_144482979 1.934 NM_011303
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chrX_-_13423666 1.925 NM_009806
Cask
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr13_-_29045399 1.917 NM_009238
Sox4
SRY-box containing gene 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
6.81 1.05e-15 GO:0007268 synaptic transmission
5.18 1.60e-14 GO:0007267 cell-cell signaling
5.71 3.30e-14 GO:0019226 transmission of nerve impulse
5.71 3.30e-14 GO:0035637 multicellular organismal signaling
2.99 3.41e-12 GO:0007399 nervous system development
3.67 1.11e-10 GO:0007154 cell communication
9.65 1.92e-09 GO:0006836 neurotransmitter transport
1.89 9.22e-09 GO:0051179 localization
2.03 4.64e-08 GO:0048731 system development
2.99 6.36e-08 GO:0022008 neurogenesis
3.05 9.51e-08 GO:0048699 generation of neurons
1.94 1.19e-07 GO:0006810 transport
1.93 1.27e-07 GO:0051234 establishment of localization
6.89 1.53e-07 GO:0050890 cognition
2.91 4.30e-07 GO:0006811 ion transport
1.38 7.82e-07 GO:0065007 biological regulation
1.79 8.84e-07 GO:0032502 developmental process
1.88 1.16e-06 GO:0048856 anatomical structure development
5.38 1.27e-06 GO:0050804 regulation of synaptic transmission
1.82 1.76e-06 GO:0007275 multicellular organismal development
3.71 1.79e-06 GO:0048666 neuron development
6.51 3.85e-06 GO:0007611 learning or memory
3.80 3.94e-06 GO:0007610 behavior
4.99 4.75e-06 GO:0051969 regulation of transmission of nerve impulse
1.55 4.85e-06 GO:0032501 multicellular organismal process
3.33 6.35e-06 GO:0030001 metal ion transport
11.74 1.07e-05 GO:0007269 neurotransmitter secretion
2.77 1.82e-05 GO:0051049 regulation of transport
4.59 1.98e-05 GO:0031644 regulation of neurological system process
3.15 2.37e-05 GO:0030182 neuron differentiation
8.16 2.79e-05 GO:0001505 regulation of neurotransmitter levels
6.64 2.91e-05 GO:0003001 generation of a signal involved in cell-cell signaling
6.64 2.91e-05 GO:0023061 signal release
1.36 6.15e-05 GO:0050794 regulation of cellular process
2.94 6.97e-05 GO:0006812 cation transport
3.73 8.52e-05 GO:0031175 neuron projection development
1.97 1.44e-04 GO:0065008 regulation of biological quality
2.35 1.66e-04 GO:0032879 regulation of localization
7.68 2.04e-04 GO:0007612 learning
1.33 2.33e-04 GO:0050789 regulation of biological process
4.13 2.49e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
4.29 2.95e-04 GO:0007409 axonogenesis
7.38 3.10e-04 GO:0048167 regulation of synaptic plasticity
2.04 3.98e-04 GO:0051239 regulation of multicellular organismal process
3.94 5.00e-04 GO:0048812 neuron projection morphogenesis
1.68 7.14e-04 GO:0016043 cellular component organization
3.09 8.09e-04 GO:0006873 cellular ion homeostasis
1.85 8.27e-04 GO:0030154 cell differentiation
3.17 8.56e-04 GO:0044057 regulation of system process
1.82 1.14e-03 GO:0048869 cellular developmental process
2.94 1.24e-03 GO:0050801 ion homeostasis
3.01 1.30e-03 GO:0055082 cellular chemical homeostasis
9.84 1.44e-03 GO:0048489 synaptic vesicle transport
1.50 1.51e-03 GO:0023052 signaling
3.66 1.52e-03 GO:0045664 regulation of neuron differentiation
2.63 1.83e-03 GO:0007155 cell adhesion
2.61 2.17e-03 GO:0022610 biological adhesion
1.62 2.41e-03 GO:0071840 cellular component organization or biogenesis
3.37 2.97e-03 GO:0032990 cell part morphogenesis
2.73 3.13e-03 GO:0019725 cellular homeostasis
4.80 4.01e-03 GO:0007626 locomotory behavior
2.76 6.11e-03 GO:0030030 cell projection organization
1.73 6.61e-03 GO:0071842 cellular component organization at cellular level
2.10 7.06e-03 GO:0010646 regulation of cell communication
1.19 7.71e-03 GO:0009987 cellular process
4.51 8.00e-03 GO:0006813 potassium ion transport
17.22 8.04e-03 GO:0048488 synaptic vesicle endocytosis
3.26 8.33e-03 GO:0048858 cell projection morphogenesis
2.25 8.64e-03 GO:0051649 establishment of localization in cell
3.25 8.73e-03 GO:0000904 cell morphogenesis involved in differentiation
3.25 8.73e-03 GO:0015672 monovalent inorganic cation transport
1.91 9.10e-03 GO:0023051 regulation of signaling
3.01 9.76e-03 GO:0051960 regulation of nervous system development
2.48 1.23e-02 GO:0048878 chemical homeostasis
2.20 1.93e-02 GO:0048468 cell development
1.58 2.14e-02 GO:0048518 positive regulation of biological process
1.90 2.19e-02 GO:0009653 anatomical structure morphogenesis
3.04 2.25e-02 GO:0050767 regulation of neurogenesis
4.34 2.67e-02 GO:0006816 calcium ion transport
2.18 2.90e-02 GO:0051128 regulation of cellular component organization
2.05 2.94e-02 GO:0051641 cellular localization
2.79 2.99e-02 GO:0060284 regulation of cell development
3.95 3.30e-02 GO:0010975 regulation of neuron projection development
3.51 3.33e-02 GO:0006897 endocytosis
3.51 3.33e-02 GO:0010324 membrane invagination
1.60 3.39e-02 GO:0048522 positive regulation of cellular process
1.64 3.57e-02 GO:0071841 cellular component organization or biogenesis at cellular level
3.65 3.92e-02 GO:0031344 regulation of cell projection organization
2.02 3.94e-02 GO:0050793 regulation of developmental process
2.98 4.80e-02 GO:0046903 secretion

Gene overrepresentation in compartment category:

enrichment p-value GO term description
5.03 1.65e-20 GO:0043005 neuron projection
5.31 1.83e-19 GO:0045202 synapse
5.43 8.51e-14 GO:0044456 synapse part
2.95 9.74e-12 GO:0042995 cell projection
5.57 4.64e-11 GO:0030424 axon
5.26 7.30e-11 GO:0030425 dendrite
1.82 4.06e-10 GO:0071944 cell periphery
1.83 4.96e-10 GO:0005886 plasma membrane
6.74 1.29e-09 GO:0045211 postsynaptic membrane
15.50 1.83e-09 GO:0042734 presynaptic membrane
4.49 8.38e-09 GO:0043025 neuronal cell body
3.91 2.56e-08 GO:0044463 cell projection part
4.28 2.61e-08 GO:0044297 cell body
1.18 8.83e-08 GO:0005623 cell
1.18 8.83e-08 GO:0044464 cell part
2.41 6.14e-07 GO:0000267 cell fraction
2.07 1.18e-06 GO:0044459 plasma membrane part
6.26 1.32e-06 GO:0033267 axon part
6.08 2.05e-06 GO:0019717 synaptosome
8.27 4.65e-06 GO:0044309 neuron spine
2.49 8.31e-06 GO:0005626 insoluble fraction
19.03 9.15e-06 GO:0008328 ionotropic glutamate receptor complex
7.47 1.50e-05 GO:0014069 postsynaptic density
7.38 1.72e-05 GO:0030427 site of polarized growth
2.80 2.66e-05 GO:0030054 cell junction
7.79 3.45e-05 GO:0043197 dendritic spine
1.32 8.15e-05 GO:0016020 membrane
7.02 1.02e-04 GO:0030426 growth cone
2.37 1.40e-04 GO:0005624 membrane fraction
1.36 2.76e-04 GO:0044425 membrane part
34.44 4.65e-04 GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
7.65 2.01e-03 GO:0030665 clathrin coated vesicle membrane
2.38 2.58e-03 GO:0031226 intrinsic to plasma membrane
4.28 2.75e-03 GO:0030659 cytoplasmic vesicle membrane
4.15 3.85e-03 GO:0044433 cytoplasmic vesicle part
4.05 5.00e-03 GO:0030135 coated vesicle
2.35 6.32e-03 GO:0005887 integral to plasma membrane
4.25 6.40e-03 GO:0030136 clathrin-coated vesicle
3.88 7.72e-03 GO:0012506 vesicle membrane
8.86 1.18e-02 GO:0030666 endocytic vesicle membrane
5.91 1.40e-02 GO:0030662 coated vesicle membrane
8.16 1.91e-02 GO:0043198 dendritic shaft
4.70 2.98e-02 GO:0008021 synaptic vesicle
1.30 4.16e-02 GO:0031224 intrinsic to membrane
8.91 4.95e-02 GO:0030672 synaptic vesicle membrane

Gene overrepresentation in function category:

enrichment p-value GO term description
1.68 2.03e-12 GO:0005515 protein binding
1.30 1.20e-07 GO:0005488 binding
3.02 4.29e-07 GO:0015075 ion transmembrane transporter activity
3.34 1.51e-06 GO:0008324 cation transmembrane transporter activity
4.28 1.64e-06 GO:0022836 gated channel activity
2.76 1.97e-06 GO:0022891 substrate-specific transmembrane transporter activity
3.22 2.05e-06 GO:0019904 protein domain specific binding
2.62 3.71e-06 GO:0022857 transmembrane transporter activity
3.68 3.77e-06 GO:0005216 ion channel activity
6.30 4.70e-06 GO:0005516 calmodulin binding
3.60 5.87e-06 GO:0022838 substrate-specific channel activity
2.53 1.02e-05 GO:0022892 substrate-specific transporter activity
3.49 1.11e-05 GO:0015267 channel activity
3.48 1.17e-05 GO:0022803 passive transmembrane transporter activity
2.29 6.15e-05 GO:0005215 transporter activity
19.37 1.02e-04 GO:0005246 calcium channel regulator activity
3.91 1.41e-04 GO:0005261 cation channel activity
8.77 2.14e-04 GO:0016247 channel regulator activity
12.47 3.08e-04 GO:0008066 glutamate receptor activity
5.31 2.14e-03 GO:0015276 ligand-gated ion channel activity
5.31 2.14e-03 GO:0022834 ligand-gated channel activity
5.62 3.40e-03 GO:0030165 PDZ domain binding
9.69 8.86e-03 GO:0019888 protein phosphatase regulator activity
2.77 1.95e-02 GO:0032403 protein complex binding
15.90 2.55e-02 GO:0017075 syntaxin-1 binding
7.75 3.29e-02 GO:0019208 phosphatase regulator activity
5.37 3.55e-02 GO:0015081 sodium ion transmembrane transporter activity
4.17 4.46e-02 GO:0005267 potassium channel activity