• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: HES1.p2

Z-value: 1.329

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Top targets:

Promoter	Score	Refseq	Gene	Description
chr7_+_152082435	12.347	NM_008003	Fgf15	fibroblast growth factor 15
chr9_+_54612599	6.100	NM_013496	Crabp1	cellular retinoic acid binding protein I
chr6_-_49164469	4.880		Igf2bp3	insulin-like growth factor 2 mRNA binding protein 3
chr4_+_124334876	4.840	NM_011141	Pou3f1	POU domain, class 3, transcription factor 1
chr4_+_47366162	4.413	NM_009370	Tgfbr1	transforming growth factor, beta receptor I
chr13_-_56353523	4.326	NM_010896	Neurog1	neurogenin 1
chr9_+_21351307	3.942	NM_021531 NM_153141	Carm1	coactivator-associated arginine methyltransferase 1
chr5_+_66155358	3.714		N4bp2	NEDD4 binding protein 2
chr2_-_26359261	3.592	NM_008714	Notch1	Notch gene homolog 1 (Drosophila)
chr2_+_31805751	3.590	NM_145144	Aif1l	allograft inflammatory factor 1-like
chr11_-_97049143	3.514		Kpnb1	karyopherin (importin) beta 1
chr9_+_72510153	3.477	NM_010890	Nedd4	neural precursor cell expressed, developmentally down-regulated 4
chr11_+_32247758	3.456	NM_177364	Sh3pxd2b	SH3 and PX domains 2B
chr5_+_28492235	3.444	NM_010134	En2	engrailed 2
chr7_+_19679892	3.438	NM_011383	Six5	sine oculis-related homeobox 5 homolog (Drosophila)
chr3_-_83844042	3.420	NM_172681	D930015E06Rik	RIKEN cDNA D930015E06 gene
chr5_+_124895400	3.334		Setd8	SET domain containing (lysine methyltransferase) 8
chr6_+_4697305	3.320	NM_001040611 NM_130877	Peg10	paternally expressed 10
chr17_-_28487544	3.295	NM_001098226 NM_011566	Tead3	TEA domain family member 3
chr1_+_63319842	3.287	NM_028673	Zdbf2	zinc finger, DBF-type containing 2
chr7_-_35597470	3.249	NM_175140	Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr5_-_38215607	3.231	NM_010835	Msx1	homeobox, msh-like 1
chr11_-_77326748	3.218	NM_001024920	Trp53i13	transformation related protein 53 inducible protein 13
chr1_-_55144637	3.000		Hspd1	heat shock protein 1 (chaperonin)
chr13_-_60278723	2.919		Gas1	growth arrest specific 1
chr9_+_110034489	2.873	NM_009211	Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr10_+_11001072	2.809	NM_027968	Fbxo30	F-box protein 30
chr7_-_150646883	2.792	NM_001161624 NM_009876	Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)
chr19_-_45817227	2.783	NM_001166361 NM_001166362 NM_001166363 NM_010205	Fgf8	fibroblast growth factor 8
chr12_+_110691637	2.772	NM_001190703 NM_001190704 NM_001190705 NM_010052	Dlk1	delta-like 1 homolog (Drosophila)
chr17_-_24833089	2.754	NM_023040	Gfer	growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)
chr2_-_37558818	2.735		Strbp	spermatid perinuclear RNA binding protein
chr11_+_117127762	2.723		Sept9	septin 9
chr5_-_52581705	2.714	NM_001042620 NM_007839	Dhx15	DEAH (Asp-Glu-Ala-His) box polypeptide 15
chr13_+_73901101	2.671	NM_011390	Slc12a7	solute carrier family 12, member 7
chr9_-_106789330	2.669	NM_175402	Rbm15b	RNA binding motif protein 15B
chr1_-_169215189	2.601		Uck2	uridine-cytidine kinase 2
chr17_+_78599556	2.545	NM_015800	Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)
chr17_+_29751754	2.532	NM_021419	Rnf8	ring finger protein 8
chr15_-_98764960	2.496		Tuba1b	tubulin, alpha 1B
chr16_-_78376912	2.494	NM_009770	Btg3	B-cell translocation gene 3
chr2_+_19367264	2.445	NM_018809	Ptf1a	pancreas specific transcription factor, 1a
chr1_+_134212642	2.437	NM_001195025 NM_028778	Nuak2	NUAK family, SNF1-like kinase, 2
chr1_-_55144687	2.403	NM_010477	Hspd1	heat shock protein 1 (chaperonin)
chr4_-_33037783	2.383	NM_001012451	Ankrd6	ankyrin repeat domain 6
chr5_-_66089061	2.372	NM_001081321	Pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr16_-_44558929	2.356	NM_172506	Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr11_-_77978936	2.342	NM_009423	Traf4	TNF receptor associated factor 4
chr2_-_181333786	2.334	NM_172676	Samd10	sterile alpha motif domain containing 10
chr2_+_117937623	2.323	NM_011580	Thbs1	thrombospondin 1
chr5_+_129526060	2.317		Ran	RAN, member RAS oncogene family
chr15_-_75739695	2.314	NM_023240 NM_029663	Eef1d	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr3_-_107889507	2.304	NM_028779	Ampd2	adenosine monophosphate deaminase 2
chr3_+_30993952	2.304	NM_001039090 NM_011386	Skil	SKI-like
chr15_-_39775173	2.291	NM_172814	Lrp12	low density lipoprotein-related protein 12
chr12_-_114067537	2.291	NM_028023	Cdca4	cell division cycle associated 4
chr13_+_73764358	2.289	NM_009354	Tert	telomerase reverse transcriptase
chr11_+_115676023	2.239	NM_029557	Tsen54	tRNA splicing endonuclease 54 homolog (S. cerevisiae)
chr15_-_95358674	2.238		Nell2	NEL-like 2 (chicken)
chr8_-_90885848	2.238		Brd7	bromodomain containing 7
chr14_-_65881225	2.233	NM_021458	Fzd3	frizzled homolog 3 (Drosophila)
chr2_-_154395469	2.232	NM_007891	E2f1	E2F transcription factor 1
chr11_-_97049185	2.224	NM_008379	Kpnb1	karyopherin (importin) beta 1
chr17_-_15963372	2.223	NM_178615	Rgmb	RGM domain family, member B
chr17_-_46766302	2.221	NM_175168	Ptk7	PTK7 protein tyrosine kinase 7
chr5_-_111239017	2.212	NM_009469	Ulk1	Unc-51 like kinase 1 (C. elegans)
chr13_-_76081244	2.186	NM_028493	Rhobtb3	Rho-related BTB domain containing 3
chr4_+_33069972	2.184	NM_027491	Rragd	Ras-related GTP binding D
chr11_+_118884275	2.172	NM_007623	Cbx2	chromobox homolog 2 (Drosophila Pc class)
chr5_-_137043355	2.151
chr18_+_70727897	2.149	NM_010773	Mbd2	methyl-CpG binding domain protein 2
chr18_-_46358466	2.144	NM_001170855	Trim36	tripartite motif-containing 36
chr18_+_85020742	2.140		Cyb5	cytochrome b-5
chr1_-_91827726	2.117	NM_010262	Gbx2	gastrulation brain homeobox 2
chr1_-_169215216	2.114	NM_030724	Uck2	uridine-cytidine kinase 2
chr4_-_81088575	2.054	NM_010820	Mpdz	multiple PDZ domain protein
chr17_+_35031503	2.054	NM_198886	Zbtb12	zinc finger and BTB domain containing 12
chr7_+_104230260	2.047	NM_001162477 NM_010248	Gab2	growth factor receptor bound protein 2-associated protein 2
chr1_-_158869650	2.044	NM_001159965 NM_001159967 NM_001159968 NM_023884	Ralgps2	Ral GEF with PH domain and SH3 binding motif 2
chr3_+_19088109	2.039	NM_026182	Mtfr1	mitochondrial fission regulator 1
chr5_+_125343129	2.034		Zfp664	zinc finger protein 664
chr8_-_64238879	2.023		Palld	palladin, cytoskeletal associated protein
chr13_-_72101161	2.023	NM_010573	Irx1	Iroquois related homeobox 1 (Drosophila)
chr8_-_81032730	2.015		Rbmxrt	RNA binding motif protein, X chromosome retrogene
chr3_-_130412297	2.002		Ostc	oligosaccharyltransferase complex subunit
chr8_+_13338741	1.980		Tfdp1	transcription factor Dp 1
chr14_+_76245136	1.966		Tpt1	tumor protein, translationally-controlled 1
chr2_+_154617083	1.956		Raly a	hnRNP-associated with lethal yellow nonagouti
chr9_+_74709673	1.940	NM_008262	Onecut1	one cut domain, family member 1
chr5_+_77694506	1.933	NM_011263	Rest	RE1-silencing transcription factor
chr6_-_39156706	1.922	NM_001033430	Jhdm1d	jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr15_-_73253534	1.918		Ptk2	PTK2 protein tyrosine kinase 2
chr1_+_91476810	1.912		Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr1_-_153937097	1.899		1700025G04Rik	RIKEN cDNA 1700025G04 gene
chr7_+_73205454	1.899		Snrpa1	small nuclear ribonucleoprotein polypeptide A'
chr16_+_72663393	1.895	NM_019413	Robo1	roundabout homolog 1 (Drosophila)
chr12_+_112404645	1.889	NM_001048206 NM_011632	Traf3	TNF receptor-associated factor 3
chr16_+_27388907	1.889	NM_001025615 NM_026202	Ccdc50	coiled-coil domain containing 50
chr16_-_17928207	1.883		Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chr2_+_158450623	1.858	NM_175419	Actr5	ARP5 actin-related protein 5 homolog (yeast)
chr13_-_41315751	1.837	NM_019423	Elovl2	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2
chr1_-_21069242	1.835	NM_133252 NM_177409	Tram2	translocating chain-associating membrane protein 2
chr16_+_92058498	1.834	NM_080456 NM_017391	Mrps6 Slc5a3	mitochondrial ribosomal protein S6 solute carrier family 5 (inositol transporters), member 3
chr17_+_46339730	1.828	NM_028198	Xpo5	exportin 5
chr12_+_9036802	1.826	NM_029321	Ttc32	tetratricopeptide repeat domain 32
chr14_-_19164241	1.816	NM_009455	Ube2e1	ubiquitin-conjugating enzyme E2E 1, UBC4/5 homolog (yeast)
chr2_-_136942066	1.807	NM_013822	Jag1	jagged 1
chr10_+_107769093	1.803	NM_054056	Pawr	PRKC, apoptosis, WT1, regulator
chr4_-_19497166	1.778	NM_027769	Cpne3	copine III
chr9_+_54829272	1.776		Chrna5	cholinergic receptor, nicotinic, alpha polypeptide 5
chr19_-_40345985	1.771		Pdlim1	PDZ and LIM domain 1 (elfin)
chr5_-_21290971	1.750	NM_009584	Dnajc2	DnaJ (Hsp40) homolog, subfamily C, member 2
chr7_-_29383163	1.726		Pak4	p21 protein (Cdc42/Rac)-activated kinase 4
chr18_+_24363784	1.719	NM_013814	Galnt1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr9_+_50665024	1.709	NM_001034085 NM_028614	Ppp2r1b	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform
chr17_+_71965554	1.705	NM_175639	Wdr43	WD repeat domain 43
chr6_+_88415396	1.704	NM_019685	Ruvbl1	RuvB-like protein 1
chr4_+_56815193	1.696	NM_001081420	BC026590	cDNA sequence BC026590
chr17_-_33822327	1.685	NM_001109913 NM_029804	Hnrnpm	heterogeneous nuclear ribonucleoprotein M
chr12_+_79849894	1.685		Mpp5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr12_-_114238815	1.670	NM_028193	Brf1	BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)
chr17_-_31992708	1.663	NM_010831	Sik1	salt inducible kinase 1
chr8_-_64238843	1.658		Palld	palladin, cytoskeletal associated protein
chr14_+_77556622	1.644	NM_172813	Enox1	ecto-NOX disulfide-thiol exchanger 1
chr4_+_129190872	1.642		Marcksl1	MARCKS-like 1
chr2_+_156665812	1.639	NM_173396	Tgif2	TGFB-induced factor homeobox 2
chr6_-_114987860	1.628	NM_026894	1500001M20Rik	RIKEN cDNA 1500001M20 gene
chr12_-_103196366	1.627	NM_001167914 NM_029705	Atxn3	ataxin 3
chr7_-_147234897	1.625	NM_010836	Msx3	homeobox, msh-like 3
chr8_+_87493507	1.612	NM_011563	Prdx2	peroxiredoxin 2
chr2_+_14976877	1.598	NM_029466	Arl5b	ADP-ribosylation factor-like 5B
chr2_-_37558794	1.596		Strbp	spermatid perinuclear RNA binding protein
chr5_+_140019846	1.595	NM_013702	Uncx	UNC homeobox
chr12_+_109661287	1.578		Eml1	echinoderm microtubule associated protein like 1
chr2_+_25036276	1.577	NM_025980	Nrarp	Notch-regulated ankyrin repeat protein
chr10_+_110357230	1.576	NM_007792	Csrp2	cysteine and glycine-rich protein 2
chr4_+_13670582	1.568		Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_30431701	1.567	NM_001167879	Fam59b	family with sequence similarity 59, member B
chr15_-_73253659	1.566		Ptk2	PTK2 protein tyrosine kinase 2
chr5_-_123350242	1.548	NM_013910	Kdm2b	lysine (K)-specific demethylase 2B
chr5_+_125343060	1.536	NM_001081750	Zfp664	zinc finger protein 664
chr19_-_12575943	1.535		Dtx4	deltex 4 homolog (Drosophila)
chr10_-_39977451	1.531	NM_026113	Gtf3c6	general transcription factor IIIC, polypeptide 6, alpha
chr7_-_29383178	1.530		Pak4	p21 protein (Cdc42/Rac)-activated kinase 4
chr1_+_159342882	1.528		2810025M15Rik	RIKEN cDNA 2810025M15 gene
chr7_-_17199935	1.527		Grlf1	glucocorticoid receptor DNA binding factor 1
chr2_-_76486033	1.520	NM_011871	Prkra	protein kinase, interferon inducible double stranded RNA dependent activator
chr12_+_110691432	1.511		Dlk1	delta-like 1 homolog (Drosophila)
chr2_-_105239368	1.511	NM_009037	Rcn1	reticulocalbin 1
chr17_-_79420125	1.505	NM_001171004 NM_029239	Prkd3	protein kinase D3
chr15_-_95358989	1.496		Nell2	NEL-like 2 (chicken)
chr8_-_122099015	1.483		Hsdl1	hydroxysteroid dehydrogenase like 1
chr12_+_114336416	1.480	NM_054081	Mta1	metastasis associated 1
chr4_+_147965596	1.477	NM_009272	Srm	spermidine synthase
chr10_+_79144868	1.471	NM_177613	Cdc34	cell division cycle 34 homolog (S. cerevisiae)
chr19_-_40346017	1.464		Pdlim1	PDZ and LIM domain 1 (elfin)
chr5_+_138220097	1.462	NM_027242	2010007H12Rik	RIKEN cDNA 2010007H12 gene
chr7_+_80536124	1.462		Rgma	RGM domain family, member A
chr4_-_154010868	1.452	NM_001177995 NM_027504	Prdm16	PR domain containing 16
chr18_+_83080270	1.443	NM_183033	Zfp516	zinc finger protein 516
chr4_-_122638401	1.433	NM_029662	Mfsd2a	major facilitator superfamily domain containing 2A
chr2_-_165980462	1.430		Sulf2	sulfatase 2
chr2_-_68310324	1.426		Stk39	serine/threonine kinase 39, STE20/SPS1 homolog (yeast)
chr5_-_23536439	1.423		Fam126a	family with sequence similarity 126, member A
chr2_-_103637096	1.423	NM_001111289 NM_001111290 NM_001111292	Caprin1	cell cycle associated protein 1
chr16_+_16303044	1.423	NM_198246	Yars2	tyrosyl-tRNA synthetase 2 (mitochondrial)
chr12_-_99812921	1.421		Kcnk10	potassium channel, subfamily K, member 10
chr1_+_58052814	1.418	NM_199007	Sgol2	shugoshin-like 2 (S. pombe)
chr6_-_39507593	1.416		Dennd2a	DENN/MADD domain containing 2A
chr13_+_69750891	1.414	NM_145354	Nsun2	NOL1/NOP2/Sun domain family member 2
chr1_-_159342713	1.413	NM_177644	Rasal2	RAS protein activator like 2
chr5_+_17080553	1.413	NM_013657	Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr6_+_125045998	1.410	NM_145979	Chd4	chromodomain helicase DNA binding protein 4
chr11_-_53113895	1.407	NM_008300	Hspa4	heat shock protein 4
chr19_+_5366812	1.406	NM_027236	Eif1ad	eukaryotic translation initiation factor 1A domain containing
chr7_+_13609719	1.402		Trim28	tripartite motif-containing 28
chr8_+_97876182	1.402	NM_008609	Mmp15	matrix metallopeptidase 15
chr10_-_79896330	1.402		Tcf3	transcription factor 3
chr2_+_75497282	1.400	NM_053263 NM_146130 NM_198090	Hnrnpa3 Gm6793	heterogeneous nuclear ribonucleoprotein A3 heterogeneous nuclear ribonucleoprotein A3 pseudogene
chr14_-_71166340	1.399	NM_023045	Xpo7	exportin 7
chr7_+_73205419	1.398		Snrpa1	small nuclear ribonucleoprotein polypeptide A'
chr2_-_73613381	1.396	NM_001113246 NM_001166603	Chn1	chimerin (chimaerin) 1
chr17_-_15963016	1.393		Rgmb	RGM domain family, member B
chr2_-_27331122	1.393	NM_001113573 NM_001113574	Brd3	bromodomain containing 3
chr10_-_75395207	1.387	NM_008606	Mmp11	matrix metallopeptidase 11
chr14_-_56341060	1.384		Rabggta	Rab geranylgeranyl transferase, a subunit
chr2_+_93027704	1.372	NM_001025246	Trp53i11	transformation related protein 53 inducible protein 11
chr3_-_141832171	1.372		Bmpr1b	bone morphogenetic protein receptor, type 1B
chr2_+_158620555	1.369	NM_145742	Dhx35	DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr10_-_17742931	1.368	NM_028440	3110003A17Rik	RIKEN cDNA 3110003A17 gene
chr17_-_35137690	1.368		D17H6S56E-5	DNA segment, Chr 17, human D6S56E 5
chr2_-_165981138	1.351	NM_028072	Sulf2	sulfatase 2
chr2_-_11524766	1.344	NM_152824	Rbm17	RNA binding motif protein 17
chr9_-_20703010	1.343	NM_016876	Eif3g	eukaryotic translation initiation factor 3, subunit G
chr6_-_72389491	1.342	NM_145569	Mat2a	methionine adenosyltransferase II, alpha
chr9_-_103267867	1.341		Cdv3	carnitine deficiency-associated gene expressed in ventricle 3
chr5_+_38611707	1.335	NM_025281	Lyar	Ly1 antibody reactive clone
chr3_+_87752614	1.329	NM_007759	Crabp2	cellular retinoic acid binding protein II
chr4_+_44313764	1.329	NM_010790	Melk	maternal embryonic leucine zipper kinase
chr4_-_71861922	1.327		Tle1	transducin-like enhancer of split 1, homolog of Drosophila E(spl)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.04	1.83e-15	GO:0044260	cellular macromolecule metabolic process
1.81	4.16e-15	GO:0044237	cellular metabolic process
1.76	9.68e-14	GO:0044238	primary metabolic process
1.88	7.15e-13	GO:0043170	macromolecule metabolic process
2.24	1.17e-12	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.11	7.18e-12	GO:0031323	regulation of cellular metabolic process
2.14	9.82e-12	GO:0060255	regulation of macromolecule metabolic process
2.01	1.22e-11	GO:0019222	regulation of metabolic process
1.63	1.35e-11	GO:0008152	metabolic process
2.37	1.73e-11	GO:0010467	gene expression
2.33	1.84e-11	GO:0010468	regulation of gene expression
3.27	2.12e-11	GO:0007399	nervous system development
2.31	3.33e-11	GO:0090304	nucleic acid metabolic process
2.09	3.42e-11	GO:0080090	regulation of primary metabolic process
2.16	3.60e-11	GO:0032502	developmental process
2.41	3.63e-11	GO:0048731	system development
2.09	3.69e-11	GO:0034641	cellular nitrogen compound metabolic process
2.30	6.96e-11	GO:0048856	anatomical structure development
2.41	8.29e-11	GO:0016070	RNA metabolic process
2.20	1.03e-10	GO:0007275	multicellular organismal development
2.39	1.34e-10	GO:0051252	regulation of RNA metabolic process
2.27	1.48e-10	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.03	2.04e-10	GO:0006807	nitrogen compound metabolic process
2.24	2.66e-10	GO:0051171	regulation of nitrogen compound metabolic process
2.38	4.20e-10	GO:0006355	regulation of transcription, DNA-dependent
2.30	4.97e-10	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.27	6.53e-10	GO:0010556	regulation of macromolecule biosynthetic process
2.20	1.21e-09	GO:0009889	regulation of biosynthetic process
2.20	1.68e-09	GO:0031326	regulation of cellular biosynthetic process
2.24	1.12e-08	GO:0009059	macromolecule biosynthetic process
2.33	1.93e-08	GO:0048523	negative regulation of cellular process
2.23	2.06e-08	GO:0034645	cellular macromolecule biosynthetic process
3.05	2.75e-08	GO:0009892	negative regulation of metabolic process
2.01	3.62e-08	GO:0009058	biosynthetic process
2.02	4.77e-08	GO:0044249	cellular biosynthetic process
1.32	6.18e-08	GO:0009987	cellular process
2.21	6.19e-08	GO:0048519	negative regulation of biological process
3.10	8.80e-08	GO:0031324	negative regulation of cellular metabolic process
3.08	1.01e-07	GO:0010605	negative regulation of macromolecule metabolic process
3.30	2.29e-07	GO:0007049	cell cycle
4.85	2.56e-07	GO:0007423	sensory organ development
2.41	3.29e-07	GO:0006351	transcription, DNA-dependent
2.40	3.53e-07	GO:0032774	RNA biosynthetic process
2.26	1.24e-06	GO:0030154	cell differentiation
3.16	1.27e-06	GO:0022008	neurogenesis
2.34	1.34e-06	GO:0048513	organ development
3.38	2.42e-06	GO:0010629	negative regulation of gene expression
1.98	2.55e-06	GO:0048518	positive regulation of biological process
3.19	3.16e-06	GO:0048699	generation of neurons
4.08	3.75e-06	GO:0048598	embryonic morphogenesis
2.19	3.94e-06	GO:0048869	cellular developmental process
2.15	4.28e-06	GO:0071842	cellular component organization at cellular level
3.57	4.29e-06	GO:0022402	cell cycle process
3.46	4.60e-06	GO:0051253	negative regulation of RNA metabolic process
2.03	5.14e-06	GO:0048522	positive regulation of cellular process
2.11	5.17e-06	GO:0071841	cellular component organization or biogenesis at cellular level
3.18	6.01e-06	GO:0031327	negative regulation of cellular biosynthetic process
2.51	6.31e-06	GO:0009653	anatomical structure morphogenesis
2.95	8.51e-06	GO:0009888	tissue development
3.11	1.07e-05	GO:0009890	negative regulation of biosynthetic process
3.25	1.07e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.62	1.12e-05	GO:0030182	neuron differentiation
8.00	1.13e-05	GO:0021915	neural tube development
3.40	1.29e-05	GO:0045892	negative regulation of transcription, DNA-dependent
3.21	1.43e-05	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
3.20	1.53e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
1.91	1.76e-05	GO:0016043	cellular component organization
4.37	2.23e-05	GO:0051301	cell division
1.88	2.29e-05	GO:0071840	cellular component organization or biogenesis
3.86	2.38e-05	GO:0007417	central nervous system development
4.72	3.24e-05	GO:0002009	morphogenesis of an epithelium
3.09	3.58e-05	GO:0010558	negative regulation of macromolecule biosynthetic process
2.92	4.83e-05	GO:0009790	embryo development
2.96	5.51e-05	GO:0045595	regulation of cell differentiation
3.22	7.30e-05	GO:0009887	organ morphogenesis
2.81	1.11e-04	GO:0048468	cell development
1.41	1.12e-04	GO:0050794	regulation of cellular process
4.14	1.21e-04	GO:0007420	brain development
1.37	1.97e-04	GO:0065007	biological regulation
6.94	2.07e-04	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.44	2.08e-04	GO:0009966	regulation of signal transduction
3.62	2.84e-04	GO:0022403	cell cycle phase
1.97	2.85e-04	GO:0044267	cellular protein metabolic process
3.65	4.73e-04	GO:0060429	epithelium development
1.37	4.90e-04	GO:0050789	regulation of biological process
3.27	5.05e-04	GO:0048646	anatomical structure formation involved in morphogenesis
2.23	5.43e-04	GO:0006996	organelle organization
7.08	5.57e-04	GO:0016331	morphogenesis of embryonic epithelium
3.76	5.58e-04	GO:0048729	tissue morphogenesis
4.07	6.86e-04	GO:0000904	cell morphogenesis involved in differentiation
4.28	7.01e-04	GO:0001501	skeletal system development
3.55	7.43e-04	GO:0023057	negative regulation of signaling
3.69	7.54e-04	GO:0009968	negative regulation of signal transduction
3.54	7.73e-04	GO:0010648	negative regulation of cell communication
4.03	7.93e-04	GO:0045596	negative regulation of cell differentiation
3.67	8.21e-04	GO:0000278	mitotic cell cycle
2.46	1.13e-03	GO:0050793	regulation of developmental process
4.55	1.54e-03	GO:0035239	tube morphogenesis
3.83	1.66e-03	GO:0035295	tube development
9.58	2.14e-03	GO:0001843	neural tube closure
6.90	2.40e-03	GO:0042471	ear morphogenesis
2.45	2.42e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
9.42	2.45e-03	GO:0060606	tube closure
9.10	3.18e-03	GO:0014020	primary neural tube formation
3.49	3.35e-03	GO:0051093	negative regulation of developmental process
2.12	3.79e-03	GO:0023051	regulation of signaling
5.29	3.90e-03	GO:0048705	skeletal system morphogenesis
4.85	3.96e-03	GO:0043010	camera-type eye development
8.81	4.10e-03	GO:0060348	bone development
2.03	4.27e-03	GO:0006464	protein modification process
7.40	4.37e-03	GO:0001838	embryonic epithelial tube formation
7.40	4.37e-03	GO:0072175	epithelial tube formation
4.45	4.60e-03	GO:0001654	eye development
5.69	4.95e-03	GO:0043583	ear development
4.41	5.12e-03	GO:0007409	axonogenesis
7.23	5.33e-03	GO:0060485	mesenchyme development
10.39	5.54e-03	GO:0030509	BMP signaling pathway
3.64	6.47e-03	GO:0031175	neuron projection development
1.97	6.88e-03	GO:0043412	macromolecule modification
6.98	7.12e-03	GO:0035148	tube formation
3.00	1.05e-02	GO:0048585	negative regulation of response to stimulus
1.48	1.07e-02	GO:0032501	multicellular organismal process
3.50	1.09e-02	GO:0000279	M phase
3.21	1.10e-02	GO:0048666	neuron development
27.30	1.11e-02	GO:0030917	midbrain-hindbrain boundary development
7.69	1.15e-02	GO:0001841	neural tube formation
4.71	1.28e-02	GO:0060562	epithelial tube morphogenesis
2.38	1.34e-02	GO:0042127	regulation of cell proliferation
3.17	1.35e-02	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
4.02	1.48e-02	GO:0048667	cell morphogenesis involved in neuron differentiation
1.70	1.69e-02	GO:0019538	protein metabolic process
7.28	1.74e-02	GO:0048762	mesenchymal cell differentiation
5.51	1.83e-02	GO:0007411	axon guidance
3.10	1.83e-02	GO:0000902	cell morphogenesis
3.34	2.02e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.95	2.35e-02	GO:0048583	regulation of response to stimulus
4.11	2.38e-02	GO:0030900	forebrain development
3.84	2.45e-02	GO:0048812	neuron projection morphogenesis
22.75	2.57e-02	GO:0021903	rostrocaudal neural tube patterning
3.43	2.60e-02	GO:0016568	chromatin modification
4.05	2.75e-02	GO:0000280	nuclear division
4.05	2.75e-02	GO:0007067	mitosis
6.83	2.80e-02	GO:0030902	hindbrain development
4.34	2.94e-02	GO:0048562	embryonic organ morphogenesis
3.22	3.22e-02	GO:0051960	regulation of nervous system development
13.65	3.43e-02	GO:0030901	midbrain development
3.96	3.49e-02	GO:0000087	M phase of mitotic cell cycle
2.38	3.72e-02	GO:0016310	phosphorylation
2.94	3.81e-02	GO:0051726	regulation of cell cycle
6.50	4.01e-02	GO:0042472	inner ear morphogenesis
7.71	4.17e-02	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.17	4.18e-02	GO:0010646	regulation of cell communication
3.89	4.20e-02	GO:0048285	organelle fission
2.31	4.47e-02	GO:2000026	regulation of multicellular organismal development
9.52	4.55e-02	GO:0061351	neural precursor cell proliferation
7.59	4.63e-02	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
4.14	4.65e-02	GO:0031344	regulation of cell projection organization
5.54	4.70e-02	GO:0048839	inner ear development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.48	1.89e-16	GO:0005622	intracellular
1.99	2.12e-16	GO:0005634	nucleus
1.48	2.05e-15	GO:0044424	intracellular part
2.74	1.91e-12	GO:0044428	nuclear part
1.54	3.99e-11	GO:0043231	intracellular membrane-bounded organelle
1.54	4.93e-11	GO:0043227	membrane-bounded organelle
1.48	6.54e-11	GO:0043229	intracellular organelle
1.48	8.97e-11	GO:0043226	organelle
2.57	5.32e-08	GO:0031981	nuclear lumen
1.20	1.77e-07	GO:0005623	cell
1.20	1.77e-07	GO:0044464	cell part
1.89	1.79e-07	GO:0032991	macromolecular complex
1.76	3.10e-07	GO:0044446	intracellular organelle part
1.73	9.00e-07	GO:0044422	organelle part
2.27	2.60e-06	GO:0070013	intracellular organelle lumen
2.27	2.77e-06	GO:0043233	organelle lumen
2.22	5.48e-06	GO:0031974	membrane-enclosed lumen
2.69	5.68e-06	GO:0005654	nucleoplasm
1.84	3.55e-05	GO:0043234	protein complex
2.73	7.70e-04	GO:0044451	nucleoplasm part
1.34	8.00e-04	GO:0005737	cytoplasm
5.10	5.61e-03	GO:0005681	spliceosomal complex
21.00	5.73e-03	GO:0016581	NuRD complex
2.92	6.34e-03	GO:0005694	chromosome
7.59	7.24e-03	GO:0000792	heterochromatin
3.00	7.35e-03	GO:0044427	chromosomal part
1.69	8.71e-03	GO:0043228	non-membrane-bounded organelle
1.69	8.71e-03	GO:0043232	intracellular non-membrane-bounded organelle
8.90	1.05e-02	GO:0017053	transcriptional repressor complex
5.90	3.64e-02	GO:0016585	chromatin remodeling complex
1.84	3.84e-02	GO:0005829	cytosol
8.98	4.33e-02	GO:0000118	histone deacetylase complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.54	1.38e-20	GO:0005488	binding
2.35	3.34e-12	GO:0003676	nucleic acid binding
1.74	6.13e-11	GO:0005515	protein binding
2.07	5.09e-06	GO:0000166	nucleotide binding
3.08	7.15e-06	GO:0003723	RNA binding
2.72	1.89e-05	GO:0030528	transcription regulator activity
2.14	2.38e-05	GO:0003677	DNA binding
2.57	1.14e-04	GO:0016772	transferase activity, transferring phosphorus-containing groups
2.07	1.58e-04	GO:0016740	transferase activity
3.93	2.23e-04	GO:0016564	transcription repressor activity
2.81	5.73e-04	GO:0043565	sequence-specific DNA binding
2.47	2.63e-03	GO:0016301	kinase activity
2.04	4.10e-03	GO:0008270	zinc ion binding
2.79	5.97e-03	GO:0019904	protein domain specific binding
4.04	1.15e-02	GO:0003682	chromatin binding
2.33	1.96e-02	GO:0001071	nucleic acid binding transcription factor activity
2.33	1.96e-02	GO:0003700	sequence-specific DNA binding transcription factor activity
10.04	3.11e-02	GO:0002039	p53 binding
1.76	4.04e-02	GO:0032555	purine ribonucleotide binding
1.76	4.09e-02	GO:0032553	ribonucleotide binding
1.75	4.42e-02	GO:0017076	purine nucleotide binding
1.79	4.62e-02	GO:0046914	transition metal ion binding