Motif ID: HIF1A.p2

Z-value: 1.443

Transcription factors associated with HIF1A.p2:

NameEntrezDescription
Hif1a 15251 hypoxia inducible factor 1, alpha subunit

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Hif1achr12_+_750088530.642.7e-05Click!


Activity profile for motif HIF1A.p2.

activity profile for motif HIF1A.p2


Sorted Z-values histogram for motif HIF1A.p2

Sorted Z-values for motif HIF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HIF1A.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Description
chr2_+_25036276 9.264 NM_025980
Nrarp
Notch-regulated ankyrin repeat protein
chr5_+_129526060 6.034 Ran
RAN, member RAS oncogene family
chr5_+_129526383 5.829 Ran
RAN, member RAS oncogene family
chr14_+_31832374 5.591 Pbrm1
polybromo 1
chr13_-_81772121 5.417 NM_054053
Gpr98
G protein-coupled receptor 98
chr5_+_129526311 5.326 Ran
RAN, member RAS oncogene family
chr1_-_55144637 4.962 Hspd1
heat shock protein 1 (chaperonin)
chr10_+_43198945 4.786 NM_199028
Bend3
BEN domain containing 3
chr1_-_153937097 4.739 1700025G04Rik
RIKEN cDNA 1700025G04 gene
chr17_+_35137995 4.653 Vars
valyl-tRNA synthetase
chr12_-_28027541 4.624 NM_009234
Sox11
SRY-box containing gene 11
chr3_-_107889507 4.443 NM_028779
Ampd2
adenosine monophosphate deaminase 2
chr16_+_52031733 4.364 Cblb
Casitas B-lineage lymphoma b
chr14_+_70008874 4.300 Loxl2
lysyl oxidase-like 2
chr13_-_72101161 4.291 NM_010573
Irx1
Iroquois related homeobox 1 (Drosophila)
chr16_+_70314306 4.279 Gbe1
glucan (1,4-alpha-), branching enzyme 1
chr11_-_102680467 4.238 NM_001159382
Gjc1
gap junction protein, gamma 1
chr11_+_120810346 4.029 NM_001038653
NM_001038654
Slc16a3

solute carrier family 16 (monocarboxylic acid transporters), member 3

chr16_+_52031704 4.003 Cblb
Casitas B-lineage lymphoma b
chr9_-_8004559 3.943 NM_001171147
NM_009534
Yap1

yes-associated protein 1

chr2_-_179777080 3.913 NM_011969
Psma7
proteasome (prosome, macropain) subunit, alpha type 7
chr4_-_137352181 3.862 NM_007431
Alpl
alkaline phosphatase, liver/bone/kidney
chr7_-_147234897 3.745 NM_010836
Msx3
homeobox, msh-like 3
chr1_+_174412343 3.672 NM_001145800
NM_033608
Igsf9

immunoglobulin superfamily, member 9

chr11_+_3190334 3.539 NM_019574
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr12_+_33505175 3.458 NM_021524
Nampt
nicotinamide phosphoribosyltransferase
chr3_+_87774988 3.414 NM_016701
Nes
nestin
chr1_-_55144687 3.375 NM_010477
Hspd1
heat shock protein 1 (chaperonin)
chr16_-_18248701 3.349 NM_011239
Ranbp1
RAN binding protein 1
chr1_+_55144949 3.313 NM_008303
Hspe1
heat shock protein 1 (chaperonin 10)
chr3_+_135101248 3.239 Ube2d3
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr3_+_87775081 3.236 Nes
nestin
chr11_+_118884275 3.188 NM_007623
Cbx2
chromobox homolog 2 (Drosophila Pc class)
chr9_-_63605917 3.164 Smad3
MAD homolog 3 (Drosophila)
chr19_+_18787654 3.110 NM_177640
D030056L22Rik
RIKEN cDNA D030056L22 gene
chr7_+_54101157 3.099 NM_010699
Ldha
lactate dehydrogenase A
chr9_+_107471447 3.096 NM_010489
Hyal2
hyaluronoglucosaminidase 2
chr1_-_153937364 3.053 NM_197990
LOC545371
1700025G04Rik
hypothetical protein LOC545371
RIKEN cDNA 1700025G04 gene
chr1_-_75176965 3.024 Abcb6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr2_-_73052484 2.983 NM_025942
NM_030091
Ola1

Obg-like ATPase 1

chr8_+_49195311 2.943 NM_178788
NM_001161515
Dctd

dCMP deaminase

chr16_-_22163264 2.934 NM_183029
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr2_+_162880370 2.933 NM_008652
Mybl2
myeloblastosis oncogene-like 2
chr4_+_46463793 2.876 Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr5_+_129525943 2.864 NM_009391
Ran
RAN, member RAS oncogene family
chr18_-_34166572 2.862 Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr10_+_68675404 2.833 NM_001081347
Rhobtb1
Rho-related BTB domain containing 1
chr7_-_126138646 2.812 Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr5_-_92566671 2.793


chr5_+_125343060 2.771 NM_001081750
Zfp664
zinc finger protein 664
chr17_-_31992708 2.769 NM_010831
Sik1
salt inducible kinase 1
chr1_+_155587480 2.761 NM_011267
Rgs16
regulator of G-protein signaling 16
chr2_+_172847371 2.715 NM_019547
Rbm38
RNA binding motif protein 38
chr7_+_137789668 2.694 Tacc2
transforming, acidic coiled-coil containing protein 2
chr1_-_75176926 2.674 Abcb6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr5_+_137791332 2.641 NM_001159571
NM_010144
Ephb4

Eph receptor B4

chr15_-_10644312 2.641 NM_001166408
Rai14
retinoic acid induced 14
chr2_+_31742800 2.629 NM_011836
Lamc3
laminin gamma 3
chr7_-_26035683 2.624 NM_010155
Erf
Ets2 repressor factor
chr11_-_72225084 2.602 NM_177776
Smtnl2
smoothelin-like 2
chr1_-_163181251 2.586 NM_007453
Prdx6
peroxiredoxin 6
chr8_-_72498125 2.566 Gatad2a
GATA zinc finger domain containing 2A
chr18_-_77803843 2.554 NM_001164504
8030462N17Rik
Rnf165
RIKEN cDNA 8030462N17 gene
ring finger protein 165
chr4_-_131901576 2.553 NM_001197082
NM_133878
Rcc1

regulator of chromosome condensation 1

chr17_+_46633703 2.552 NM_207161
BC048355
cDNA sequence BC048355
chr1_+_174078145 2.471 NM_153555
Dcaf8
DDB1 and CUL4 associated factor 8
chr8_+_11556495 2.451 Ing1
inhibitor of growth family, member 1
chr8_-_64238879 2.445 Palld
palladin, cytoskeletal associated protein
chr9_-_95745663 2.416 NM_001033210
Pls1
plastin 1 (I-isoform)
chr7_-_31758185 2.408 Lsr
lipolysis stimulated lipoprotein receptor
chr5_+_28492235 2.404 NM_010134
En2
engrailed 2
chr14_+_31832323 2.399 NM_001081251
Pbrm1
polybromo 1
chr19_-_38199291 2.394 NM_011255
Rbp4
retinol binding protein 4, plasma
chr12_+_52449216 2.364 NM_001015099
NM_001167963
NM_001167964
G2e3


G2/M-phase specific E3 ubiquitin ligase


chrX_-_91077426 2.351 NM_145630
Pdk3
pyruvate dehydrogenase kinase, isoenzyme 3
chr7_-_35597470 2.346 NM_175140
Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr9_+_123387818 2.334 NM_013860
Limd1
LIM domains containing 1
chr7_-_126138689 2.326 NM_001195774
NM_022420
Gprc5b

G protein-coupled receptor, family C, group 5, member B

chr12_+_33505307 2.326 Nampt
nicotinamide phosphoribosyltransferase
chr6_-_88848650 2.301 NM_008564
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr9_+_64988960 2.287 NM_008988
Igdcc3
immunoglobulin superfamily, DCC subclass, member 3
chr7_+_13609462 2.273 NM_011588
Trim28
tripartite motif-containing 28
chr17_+_68046597 2.273 NM_008480
Lama1
laminin, alpha 1
chr10_+_79689342 2.270 NM_023431
Mum1
melanoma associated antigen (mutated) 1
chr13_+_81796756 2.261 NM_030257
Lysmd3
LysM, putative peptidoglycan-binding, domain containing 3
chr2_+_167363696 2.251 NM_011427
Snai1
snail homolog 1 (Drosophila)
chr17_+_74738195 2.236 NM_001162870
NM_016962
Spast

spastin

chr5_-_124875507 2.207 Sbno1
sno, strawberry notch homolog 1 (Drosophila)
chr19_+_41557475 2.205 Lcor
ligand dependent nuclear receptor corepressor
chr9_-_59598416 2.194 NM_001172068
NM_001172069
NM_001172070
NM_001172071
NM_027838
Senp8




SUMO/sentrin specific peptidase 8




chrX_+_103382432 2.193 NM_008828
Pgk1
phosphoglycerate kinase 1
chr6_-_6167113 2.182 NM_001177572
NM_015829
Slc25a13

solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13

chr9_+_50665024 2.175 NM_001034085
NM_028614
Ppp2r1b

protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform

chr14_-_65881225 2.175 NM_021458
Fzd3
frizzled homolog 3 (Drosophila)
chr9_+_61220162 2.174 NM_001083927
NM_001083928
NM_009389
Tle3


transducin-like enhancer of split 3, homolog of Drosophila E(spl)


chr9_-_66440640 2.159 NM_144937
Usp3
ubiquitin specific peptidase 3
chr2_+_92024338 2.151 NM_138755
Phf21a
PHD finger protein 21A
chr3_+_32607582 2.138 Actl6a
actin-like 6A
chr14_+_31832347 2.132 Pbrm1
polybromo 1
chr12_-_70298068 2.121 1110034A24Rik
RIKEN cDNA 1110034A24 gene
chr12_-_104480335 2.117 NM_133364
Prima1
proline rich membrane anchor 1
chr1_+_122499031 2.106 NM_010133
En1
engrailed 1
chr11_+_60351469 2.085 Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr1_-_38186482 2.084 NM_019570
Rev1
REV1 homolog (S. cerevisiae)
chr8_-_123112974 2.080 NM_178856
Gins2
GINS complex subunit 2 (Psf2 homolog)
chr1_-_120950111 2.032 NM_001081125
Gli2
GLI-Kruppel family member GLI2
chr6_-_39507593 1.999 Dennd2a
DENN/MADD domain containing 2A
chr6_-_97010364 1.997 NM_177233
Fam19a4
family with sequence similarity 19, member A4
chr8_+_34842304 1.997 NM_001167921
Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
chr16_-_22163035 1.974 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr13_-_21532756 1.957 NM_001012311
NM_001162920
Pgbd1

piggyBac transposable element derived 1

chr19_+_36908682 1.951 NM_001163635
Tnks2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr5_-_134790544 1.930 NM_001080746
NM_001080747
NM_001080748
NM_001080749
NM_010365
Gtf2i




general transcription factor II I




chr7_+_104936996 1.930 Pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr8_+_109127245 1.924 NM_009864
Cdh1
cadherin 1
chr5_+_73398142 1.922 NM_173403
Slc10a4
solute carrier family 10 (sodium/bile acid cotransporter family), member 4
chr15_-_93167238 1.914 Yaf2
YY1 associated factor 2
chr11_-_57981970 1.913 Gemin5
gem (nuclear organelle) associated protein 5
chr12_-_103196366 1.907 NM_001167914
NM_029705
Atxn3

ataxin 3

chr9_+_110235785 1.895 NM_001001144
NM_001103162
Scap

SREBF chaperone

chr11_+_97177029 1.871 NM_025927
Mrpl45
mitochondrial ribosomal protein L45
chr7_-_112884969 1.859 NM_025897
Rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr15_-_75739695 1.857 NM_023240
NM_029663
Eef1d

eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)

chr5_+_145016060 1.845 NM_018772
Bri3
brain protein I3
chr16_+_20672770 1.829 NM_001005331
NM_145941
Eif4g1

eukaryotic translation initiation factor 4, gamma 1

chr4_-_22415444 1.820 Pou3f2
POU domain, class 3, transcription factor 2
chr5_-_52581705 1.819 NM_001042620
NM_007839
Dhx15

DEAH (Asp-Glu-Ala-His) box polypeptide 15

chr10_+_36694322 1.807 NM_008229
Hdac2
histone deacetylase 2
chr17_-_26232411 1.798 NM_019731
Nme4
non-metastatic cells 4, protein expressed in
chr17_+_10512744 1.797 B930003M22Rik
RIKEN cDNA B930003M22 gene
chr5_-_4104331 1.786 Cyp51
cytochrome P450, family 51
chr2_+_27741864 1.762 NM_015734
Col5a1
collagen, type V, alpha 1
chr4_+_131429522 1.761 NM_020587
Srsf4
serine/arginine-rich splicing factor 4
chr5_-_8422533 1.755 NM_001190717
NM_013726
Dbf4

DBF4 homolog (S. cerevisiae)

chr1_+_61685397 1.724 NM_001081050
Pard3b
par-3 partitioning defective 3 homolog B (C. elegans)
chr13_-_99660903 1.722 NM_001048267
Tnpo1
transportin 1
chr19_+_41557126 1.719 Lcor
ligand dependent nuclear receptor corepressor
chr2_+_156665812 1.718 NM_173396
Tgif2
TGFB-induced factor homeobox 2
chr11_+_23978029 1.709 NM_001159289
NM_016707
Bcl11a

B-cell CLL/lymphoma 11A (zinc finger protein)

chr5_+_137791368 1.705 Ephb4
Eph receptor B4
chr2_+_19367264 1.697 NM_018809
Ptf1a
pancreas specific transcription factor, 1a
chr8_-_59966523 1.674 NM_021788
Sap30
sin3 associated polypeptide
chr19_+_47654060 1.661 Slk
STE20-like kinase (yeast)
chr12_+_107022903 1.659 NM_011112
Papola
poly (A) polymerase alpha
chr1_+_91351373 1.655 NM_001037136
NM_178119
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr16_+_44724394 1.654 NM_145972
BC027231
cDNA sequence BC027231
chr12_-_85559793 1.638 NM_001163501
C130039O16Rik
RIKEN cDNA C130039O16 gene
chr9_+_54997159 1.637 NM_180600
Ube2q2
ubiquitin-conjugating enzyme E2Q (putative) 2
chr3_+_152058937 1.633 NM_001080755
Zzz3
zinc finger, ZZ domain containing 3
chr7_+_54101226 1.626 Ldha
lactate dehydrogenase A
chr3_-_83844042 1.613 NM_172681
D930015E06Rik
RIKEN cDNA D930015E06 gene
chr4_+_118781336 1.612 NM_011400
Slc2a1
solute carrier family 2 (facilitated glucose transporter), member 1
chr15_+_98956940 1.605 Spats2
spermatogenesis associated, serine-rich 2
chr4_-_131978279 1.598 NM_001161797
NM_175306
Phactr4

phosphatase and actin regulator 4

chr6_-_116578970 1.596 NM_026057
Zfp422
zinc finger protein 422
chr14_+_32064678 1.591 Bap1
Brca1 associated protein 1
chr6_+_64992810 1.588 Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr5_+_30431701 1.588 NM_001167879
Fam59b
family with sequence similarity 59, member B
chrX_-_7651846 1.587 NM_011514
Suv39h1
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr5_-_111082387 1.584 NM_153570
Noc4l
nucleolar complex associated 4 homolog (S. cerevisiae)
chr1_-_39634096 1.554 NM_001033135
Rnf149
ring finger protein 149
chr6_+_64992861 1.545 Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr15_-_88971039 1.545 NM_013871
Mapk12
mitogen-activated protein kinase 12
chr6_-_134516799 1.541 Lrp6
low density lipoprotein receptor-related protein 6
chr14_+_31832340 1.539 Pbrm1
polybromo 1
chr11_+_32247758 1.535 NM_177364
Sh3pxd2b
SH3 and PX domains 2B
chr14_+_21871781 1.532 NM_134079
Adk
adenosine kinase
chr7_+_28964518 1.530 Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr14_-_31832165 1.522 Gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr10_-_68815606 1.517 NM_007659
Cdk1
cyclin-dependent kinase 1
chr17_+_35035395 1.516 NM_147151
Ehmt2
euchromatic histone lysine N-methyltransferase 2
chr4_-_21612991 1.513 NM_001080771
Prdm13
PR domain containing 13
chr4_-_133801438 1.512 NM_024215
Zfp593
zinc finger protein 593
chr6_-_89312545 1.512 NM_008881
Plxna1
plexin A1
chr9_+_107456969 1.507 NM_019713
Rassf1
Ras association (RalGDS/AF-6) domain family member 1
chr2_+_30141908 1.502 NM_198304
Nup188
nucleoporin 188
chr11_-_60624592 1.502 Shmt1
serine hydroxymethyltransferase 1 (soluble)
chr1_-_145549903 1.500 Cdc73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr2_-_174264400 1.490 NM_022325
Ctsz
cathepsin Z
chr2_+_158620555 1.489 NM_145742
Dhx35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr1_-_163181313 1.488 Prdx6
peroxiredoxin 6
chr3_-_142544883 1.484 NM_178654
Pkn2
protein kinase N2
chrX_+_93291377 1.479 NM_010833
Msn
moesin
chr2_+_27370649 1.478 NM_080848
Wdr5
WD repeat domain 5
chr19_+_7049639 1.476 Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr11_+_117710532 1.463 NM_001012273
NM_009689
Birc5

baculoviral IAP repeat-containing 5

chr3_-_146184337 1.462 NM_027332
NM_027371
Rpf1

ribosome production factor 1 homolog (S. cerevisiae)

chr16_+_20141134 1.459 NM_001033237
NM_001145930
NM_001145931
Yeats2


YEATS domain containing 2


chrX_-_159267249 1.446 NM_178935
Txlng
taxilin gamma
chr6_+_38501333 1.446 NM_001170848
NM_001170849
NM_138680
Luc7l2


LUC7-like 2 (S. cerevisiae)


chr12_-_28027272 1.444 Sox11
SRY-box containing gene 11
chr8_-_49928495 1.439 2900073C17Rik
RIKEN cDNA 2900073C17 gene
chr4_-_62186055 1.437 Pole3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr8_-_64238843 1.424 Palld
palladin, cytoskeletal associated protein
chr4_-_41688124 1.414 NM_011014
Sigmar1
sigma non-opioid intracellular receptor 1
chrX_-_72661877 1.413 NM_001039373
NM_010839
Mtcp1

mature T-cell proliferation 1

chr2_-_144096518 1.411 Snx5
sorting nexin 5
chr3_-_119486305 1.410 NM_019550
Ptbp2
polypyrimidine tract binding protein 2
chr18_+_5591869 1.403 NM_011546
Zeb1
zinc finger E-box binding homeobox 1
chr12_-_40763924 1.401 NM_007487
Arl4a
ADP-ribosylation factor-like 4A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
2.35 5.73e-15 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.19 2.45e-13 GO:0034641 cellular nitrogen compound metabolic process
2.13 1.56e-12 GO:0006807 nitrogen compound metabolic process
2.36 5.48e-12 GO:0090304 nucleic acid metabolic process
1.64 9.27e-12 GO:0008152 metabolic process
1.70 2.25e-11 GO:0044238 primary metabolic process
1.70 5.20e-11 GO:0044237 cellular metabolic process
1.86 3.06e-10 GO:0044260 cellular macromolecule metabolic process
1.79 4.89e-10 GO:0043170 macromolecule metabolic process
2.25 1.87e-09 GO:0010467 gene expression
2.28 9.46e-09 GO:0016070 RNA metabolic process
2.17 1.38e-08 GO:0010468 regulation of gene expression
2.23 4.00e-08 GO:0051252 regulation of RNA metabolic process
2.15 1.17e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.99 1.18e-07 GO:0009058 biosynthetic process
2.21 1.18e-07 GO:0006355 regulation of transcription, DNA-dependent
2.12 1.43e-07 GO:0010556 regulation of macromolecule biosynthetic process
2.00 1.59e-07 GO:0044249 cellular biosynthetic process
2.07 2.24e-07 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.05 3.67e-07 GO:0051171 regulation of nitrogen compound metabolic process
2.03 5.56e-07 GO:0009889 regulation of biosynthetic process
2.03 7.65e-07 GO:0031326 regulation of cellular biosynthetic process
2.11 8.46e-07 GO:0009059 macromolecule biosynthetic process
2.10 1.50e-06 GO:0034645 cellular macromolecule biosynthetic process
1.78 1.66e-06 GO:0019222 regulation of metabolic process
3.15 2.29e-06 GO:0007049 cell cycle
1.86 2.33e-06 GO:0060255 regulation of macromolecule metabolic process
3.88 2.42e-06 GO:0051276 chromosome organization
1.84 2.51e-06 GO:0080090 regulation of primary metabolic process
1.89 3.51e-06 GO:0032502 developmental process
1.83 3.61e-06 GO:0031323 regulation of cellular metabolic process
2.10 7.98e-06 GO:0071841 cellular component organization or biogenesis at cellular level
2.62 1.26e-05 GO:0007399 nervous system development
1.88 2.45e-05 GO:0007275 multicellular organismal development
4.15 2.47e-05 GO:0006325 chromatin organization
1.94 2.54e-05 GO:0048856 anatomical structure development
2.22 3.21e-05 GO:0006351 transcription, DNA-dependent
2.22 3.41e-05 GO:0032774 RNA biosynthetic process
2.07 4.20e-05 GO:0071842 cellular component organization at cellular level
1.98 5.38e-05 GO:0048731 system development
4.32 5.54e-05 GO:0016568 chromatin modification
1.26 1.13e-04 GO:0009987 cellular process
5.53 1.18e-04 GO:0016570 histone modification
5.45 1.45e-04 GO:0016569 covalent chromatin modification
1.82 1.48e-04 GO:0071840 cellular component organization or biogenesis
3.15 1.89e-04 GO:0051253 negative regulation of RNA metabolic process
12.83 1.95e-04 GO:0061351 neural precursor cell proliferation
2.26 3.83e-04 GO:0006996 organelle organization
2.75 4.24e-04 GO:0022008 neurogenesis
3.08 4.97e-04 GO:0045892 negative regulation of transcription, DNA-dependent
3.11 6.98e-04 GO:0022402 cell cycle process
2.88 1.07e-03 GO:0010629 negative regulation of gene expression
1.98 1.18e-03 GO:0030154 cell differentiation
1.78 1.19e-03 GO:0016043 cellular component organization
2.86 1.21e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.96 1.29e-03 GO:0048869 cellular developmental process
2.83 1.53e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.82 1.62e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
3.67 2.80e-03 GO:0007423 sensory organ development
3.13 3.03e-03 GO:0009792 embryo development ending in birth or egg hatching
2.72 3.25e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
4.49 3.85e-03 GO:0001654 eye development
3.25 5.07e-03 GO:0007417 central nervous system development
2.63 5.97e-03 GO:0031327 negative regulation of cellular biosynthetic process
3.55 8.33e-03 GO:0007420 brain development
3.03 8.41e-03 GO:0043009 chordate embryonic development
2.57 9.19e-03 GO:0009890 negative regulation of biosynthetic process
2.56 9.65e-03 GO:0048699 generation of neurons
2.50 1.01e-02 GO:0009790 embryo development
3.20 1.10e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.33 1.35e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.30 1.74e-02 GO:0010605 negative regulation of macromolecule metabolic process
4.52 1.81e-02 GO:0043010 camera-type eye development
4.15 2.01e-02 GO:0030900 forebrain development
2.85 2.16e-02 GO:0030182 neuron differentiation
3.37 3.03e-02 GO:0051301 cell division
4.27 3.24e-02 GO:0071843 cellular component biogenesis at cellular level
1.87 3.94e-02 GO:0048513 organ development
1.75 4.07e-02 GO:0044267 cellular protein metabolic process
2.23 4.09e-02 GO:0031324 negative regulation of cellular metabolic process

Gene overrepresentation in compartment category:

enrichment p-value GO term description
2.10 7.68e-20 GO:0005634 nucleus
1.51 5.75e-19 GO:0005622 intracellular
1.52 2.60e-18 GO:0044424 intracellular part
1.61 4.00e-14 GO:0043231 intracellular membrane-bounded organelle
1.60 5.06e-14 GO:0043227 membrane-bounded organelle
1.53 1.50e-13 GO:0043229 intracellular organelle
1.53 2.13e-13 GO:0043226 organelle
2.61 1.35e-10 GO:0044428 nuclear part
2.45 9.47e-07 GO:0031981 nuclear lumen
1.19 4.51e-06 GO:0005623 cell
1.19 4.51e-06 GO:0044464 cell part
2.16 3.18e-05 GO:0070013 intracellular organelle lumen
2.16 3.36e-05 GO:0043233 organelle lumen
2.12 6.25e-05 GO:0031974 membrane-enclosed lumen
1.64 6.59e-05 GO:0044446 intracellular organelle part
1.62 8.19e-05 GO:0044422 organelle part
1.36 2.14e-04 GO:0005737 cytoplasm
1.83 3.69e-04 GO:0043228 non-membrane-bounded organelle
1.83 3.69e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.67 4.96e-04 GO:0032991 macromolecular complex
7.66 5.09e-04 GO:0016585 chromatin remodeling complex
3.39 1.40e-03 GO:0005730 nucleolus
9.65 1.43e-03 GO:0030496 midbody
3.11 1.60e-03 GO:0005694 chromosome
3.20 1.82e-03 GO:0044427 chromosomal part
4.27 2.47e-03 GO:0000785 chromatin
5.49 7.78e-03 GO:0005819 spindle
4.00 1.01e-02 GO:0000228 nuclear chromosome
9.07 4.11e-02 GO:0000118 histone deacetylase complex
1.57 4.47e-02 GO:0043234 protein complex

Gene overrepresentation in function category:

enrichment p-value GO term description
2.18 2.81e-09 GO:0003676 nucleic acid binding
1.34 3.68e-07 GO:0005488 binding
2.12 4.21e-05 GO:0003677 DNA binding
4.76 4.02e-04 GO:0003682 chromatin binding
1.85 1.16e-03 GO:0000166 nucleotide binding
2.61 2.06e-03 GO:0003723 RNA binding
2.28 7.92e-03 GO:0030528 transcription regulator activity
1.40 1.08e-02 GO:0005515 protein binding
3.31 1.36e-02 GO:0016564 transcription repressor activity
1.81 2.03e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.91 2.37e-02 GO:0005524 ATP binding
1.78 3.20e-02 GO:0032555 purine ribonucleotide binding
1.78 3.24e-02 GO:0032553 ribonucleotide binding
1.87 3.43e-02 GO:0032559 adenyl ribonucleotide binding
1.77 3.51e-02 GO:0017076 purine nucleotide binding
1.86 3.79e-02 GO:0030554 adenyl nucleotide binding