• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: HOX{A5,B5}.p2

Z-value: 0.837

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Top targets:

Promoter	Score	Refseq	Gene	Description
chrX_-_161765324	7.675		Glra2	glycine receptor, alpha 2 subunit
chr11_+_56825307	6.588		Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr13_+_54472806	5.757		Cplx2	complexin 2
chr13_+_54472833	5.684		Cplx2	complexin 2
chr5_-_143084677	5.191	NM_175217	Mmd2	monocyte to macrophage differentiation-associated 2
chr17_-_57226987	5.120	NM_009451	Tubb4	tubulin, beta 4
chr13_+_54472705	5.010	NM_009946	Cplx2	complexin 2
chr6_+_110595574	4.754		Grm7	glutamate receptor, metabotropic 7
chr8_-_73011217	4.682	NM_182991	Tmem59l	transmembrane protein 59-like
chr10_+_128346900	4.351	NM_007653	Cd63	CD63 antigen
chr11_+_56825258	4.155		Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr6_+_114232767	4.054		Slc6a1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr2_+_158492854	3.687	NM_001159662	Ppp1r16b	protein phosphatase 1, regulatory (inhibitor) subunit 16B
chrX_+_133357268	3.577	NM_011123	Plp1	proteolipid protein (myelin) 1
chrM_+_2750	3.284
chr9_-_75459125	3.283	NM_016711	Tmod2	tropomodulin 2
chr17_+_31523178	3.239	NM_001163748 NM_008804	Pde9a	phosphodiesterase 9A
chr1_+_189821727	3.025	NM_011935	Esrrg	estrogen-related receptor gamma
chrM_+_13320	3.009
chr18_+_77424573	2.844	NM_013666 NM_153124	St8sia5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr11_-_74537303	2.787		Pafah1b1	platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr6_-_113451811	2.719	NM_172487	Prrt3	proline-rich transmembrane protein 3
chr8_+_115093942	2.488	NM_130457	Cntnap4	contactin associated protein-like 4
chr8_-_88364846	2.114	NM_028007	Itfg1	integrin alpha FG-GAP repeat containing 1
chr9_-_75459046	2.053		Tmod2	tropomodulin 2
chrM_+_3320	2.041
chr4_-_126430511	2.007	NM_011986	Ncdn	neurochondrin
chr11_-_95936914	1.978	NM_001161419 NM_007506	Atp5g1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr18_-_78320126	1.945	NM_001171010 NM_028122	Slc14a1	solute carrier family 14 (urea transporter), member 1
chr5_-_138404150	1.933	NM_080450	Gjc3	gap junction protein, gamma 3
chr5_+_141200067	1.930	NM_173405	Amz1	archaelysin family metallopeptidase 1
chr2_+_164793698	1.929		Slc12a5	solute carrier family 12, member 5
chr15_-_8584897	1.924		Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_+_71002395	1.894	NM_019587	Plxnb3	plexin B3
chr9_-_75458954	1.831		Tmod2	tropomodulin 2
chr11_+_70467599	1.823		Pfn1	profilin 1
chr9_-_61970402	1.771		Glce	glucuronyl C5-epimerase
chr9_-_53823107	1.716	NM_177769	Elmod1	ELMO domain containing 1
chr11_+_56825192	1.594	NM_001113325 NM_008165	Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr9_-_34924338	1.570	NM_009178	St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr7_+_134985164	1.553	NM_009294	Stx4a	syntaxin 4A (placental)
chr18_+_37637421	1.538	NM_053141	Pcdhb16	protocadherin beta 16
chr5_-_143084748	1.487		Mmd2	monocyte to macrophage differentiation-associated 2
chr2_-_26883441	1.469	NM_001177627 NM_172659	Slc2a6	solute carrier family 2 (facilitated glucose transporter), member 6
chr6_+_124946723	1.428	NM_175696	C530028O21Rik	RIKEN cDNA C530028O21 gene
chr9_-_35365985	1.399	NM_013932	Ddx25	DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr2_+_177876635	1.388	NM_028806	Phactr3	phosphatase and actin regulator 3
chr15_-_78236262	1.381	NM_009437	Tst	thiosulfate sulfurtransferase, mitochondrial
chr11_-_41995688	1.380		Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr6_-_113451922	1.370		Prrt3	proline-rich transmembrane protein 3
chr8_+_24780132	1.361	NM_177086	Zmat4	zinc finger, matrin type 4
chr2_+_68973856	1.304	NM_181547	Nostrin	nitric oxide synthase trafficker
chrX_-_69901382	1.274	NM_008067	Gabra3	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr18_-_78320014	1.260		Slc14a1	solute carrier family 14 (urea transporter), member 1
chr7_-_31699850	1.249	NM_010758	Mag	myelin-associated glycoprotein
chr11_-_119908236	1.249	NM_001198785 NM_007377	Aatk	apoptosis-associated tyrosine kinase
chr14_-_26588341	1.237	NM_001101433	Zcchc24	zinc finger, CCHC domain containing 24
chrX_-_101396356	1.213	NM_001077354	C77370	expressed sequence C77370
chrX_-_131745187	1.213	NM_025355	Tceal6	transcription elongation factor A (SII)-like 6
chr11_-_41995934	1.192		Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr7_-_134968017	1.190	NM_024414	Stx1b	syntaxin 1B
chr7_+_52419317	1.137		Slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr5_-_69732792	1.134		Kctd8	potassium channel tetramerisation domain containing 8
chr13_+_83663817	1.118		Mef2c	myocyte enhancer factor 2C
chr7_+_134985435	1.110		Stx4a	syntaxin 4A (placental)
chr6_-_18464792	1.096	NM_080285	Cttnbp2	cortactin binding protein 2
chr13_+_58909236	1.095		Ntrk2	neurotrophic tyrosine kinase, receptor, type 2
chr10_-_101953046	1.085	NM_024435	Nts	neurotensin
chr6_+_86388364	1.079	NM_146170	C87436	expressed sequence C87436
chr14_+_32973077	1.056	NM_001033988	Ncoa4	nuclear receptor coactivator 4
chr10_+_89149113	1.035		1500026H17Rik	RIKEN cDNA 1500026H17 gene
chr7_-_134164627	1.025	NM_001102563	Prrt2	proline-rich transmembrane protein 2
chr7_-_116226796	1.025	NM_001038624 NM_178780	Ric3	resistance to inhibitors of cholinesterase 3 homolog (C. elegans)
chr6_-_58857000	1.020	NM_021432	Nap1l5	nucleosome assembly protein 1-like 5
chr4_-_141430740	0.986	NM_025994	Efhd2	EF hand domain containing 2
chr5_+_52755183	0.972		Sod3	superoxide dismutase 3, extracellular
chr5_-_118694869	0.952	NM_172998 NM_001109902	Rnft2	ring finger protein, transmembrane 2
chrM_+_11741	0.949		ND5	NADH dehydrogenase subunit 5
chr12_+_71926429	0.946	NM_028127	Frmd6	FERM domain containing 6
chr7_+_52419289	0.929	NM_182993	Slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr8_-_72425538	0.909		Ndufa13	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr7_-_28327749	0.906		Pld3	phospholipase D family, member 3
chr2_-_113669229	0.904		Scg5	secretogranin V
chr7_+_120351012	0.872		Arntl	aryl hydrocarbon receptor nuclear translocator-like
chr2_+_164793796	0.861		Slc12a5	solute carrier family 12, member 5
chr19_+_56796545	0.859		Adrb1	adrenergic receptor, beta 1
chr15_+_83998239	0.859	NM_054088	Pnpla3	patatin-like phospholipase domain containing 3
chr14_+_55555300	0.848	NM_026066	Cmtm5	CKLF-like MARVEL transmembrane domain containing 5
chr14_-_55735399	0.844		Jph4	junctophilin 4
chr11_-_77303157	0.841	NM_172945	Ankrd13b	ankyrin repeat domain 13b
chr5_+_135499346	0.825	NM_016801	Stx1a	syntaxin 1A (brain)
chr9_+_64233432	0.823	NM_001134399 NM_172522	Megf11	multiple EGF-like-domains 11
chr5_+_27588462	0.800	NM_001136060	Dpp6	dipeptidylpeptidase 6
chr15_+_82105322	0.798	NM_011889	Sept3	septin 3
chr10_-_61573705	0.767	NM_027251	2010107G23Rik	RIKEN cDNA 2010107G23 gene
chrX_-_47150892	0.763	NM_177591 NM_177915	Igsf1	immunoglobulin superfamily, member 1
chr4_+_126431013	0.760	NM_001035526 NM_133886	AU040320	expressed sequence AU040320
chr13_+_88961034	0.756	NM_001037987 NM_010103	Edil3	EGF-like repeats and discoidin I-like domains 3
chr12_+_89961317	0.754	NM_001198587	Nrxn3	neurexin III
chr5_+_125956221	0.751	NM_030210	Aacs	acetoacetyl-CoA synthetase
chr11_+_102291759	0.742		Grn	granulin
chr2_-_148701164	0.730		Cst3	cystatin C
chrX_+_35954355	0.716		Mcts1	malignant T cell amplified sequence 1
chr1_+_43787692	0.716		1500015O10Rik	RIKEN cDNA 1500015O10 gene
chr4_+_144482979	0.714	NM_011303	Dhrs3	dehydrogenase/reductase (SDR family) member 3
chr6_+_88775664	0.714		Mgll	monoglyceride lipase
chr11_-_41996141	0.710	NM_010250	Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr14_-_70689267	0.709		Ppp3cc	protein phosphatase 3, catalytic subunit, gamma isoform
chr14_-_56503058	0.707		Cbln3	cerebellin 3 precursor protein
chr3_+_96400524	0.706	NM_001024851	Ankrd34a	ankyrin repeat domain 34A
chr18_+_37607310	0.701	NM_053139	Pcdhb14	protocadherin beta 14
chr6_+_122463663	0.695	NM_015776	Mfap5	microfibrillar associated protein 5
chr10_-_126648509	0.693	NM_054097	Pip4k2c	phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr4_+_128560786	0.692		Trim62	tripartite motif-containing 62
chr4_-_82151590	0.692		Nfib	nuclear factor I/B
chr7_+_127986324	0.688	NM_007908	Eef2k	eukaryotic elongation factor-2 kinase
chr8_-_88364760	0.686		Itfg1	integrin alpha FG-GAP repeat containing 1
chr15_+_78744328	0.677	NM_020271	Pdxp	pyridoxal (pyridoxine, vitamin B6) phosphatase
chr8_-_108224992	0.677	NM_001012638	Acd	adrenocortical dysplasia
chrM_+_13543	0.649
chr7_-_31699888	0.648		Mag	myelin-associated glycoprotein
chr7_+_72789752	0.633	NM_172310	Tarsl2	threonyl-tRNA synthetase-like 2
chr9_+_59598963	0.625	NM_173018	Myo9a	myosin IXa
chr7_-_52722144	0.622	NM_007527	Bax	BCL2-associated X protein
chr2_-_35192443	0.619	NM_013515	Stom	stomatin
chr3_-_88964115	0.618		Hcn3	hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr17_+_32822572	0.617	NM_134127	Cyp4f15	cytochrome P450, family 4, subfamily f, polypeptide 15
chr3_-_108830522	0.612	NM_001163567	Fam102b	family with sequence similarity 102, member B
chr15_-_34608600	0.607		Nipal2	NIPA-like domain containing 2
chr4_+_17780739	0.600		Mmp16	matrix metallopeptidase 16
chr3_+_98084352	0.594	NM_008256	Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
chr15_+_89284625	0.594		Mapk8ip2	mitogen-activated protein kinase 8 interacting protein 2
chr18_-_16967557	0.589	NM_007664	Cdh2	cadherin 2
chr2_-_113669159	0.585		Scg5	secretogranin V
chr9_-_75458918	0.582		Tmod2	tropomodulin 2
chr9_+_107302196	0.578	NM_001174047 NM_001174048 NM_001174049 NM_001174050 NM_020263	Cacna2d2	calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr2_+_180444945	0.576		2310003C23Rik	RIKEN cDNA 2310003C23 gene
chr3_-_107320831	0.575		Slc6a17	solute carrier family 6 (neurotransmitter transporter), member 17
chr19_+_5460588	0.573	NM_021438	Fibp	fibroblast growth factor (acidic) intracellular binding protein
chr7_-_25084361	0.571		Zfp61	zinc finger protein 61
chr10_-_126778941	0.565		Gli1	GLI-Kruppel family member GLI1
chr7_+_5008311	0.564	NM_146178	Ccdc106	coiled-coil domain containing 106
chr2_-_181048957	0.563		Stmn3	stathmin-like 3
chr15_-_27955602	0.561	NM_001081302	Trio	triple functional domain (PTPRF interacting)
chr14_+_56178853	0.556	NM_133734	Dcaf11	DDB1 and CUL4 associated factor 11
chr15_+_54402914	0.548	NM_178920	Mal2	mal, T-cell differentiation protein 2
chr2_+_25258653	0.541		Npdc1	neural proliferation, differentiation and control gene 1
chrX_+_138662725	0.540	NM_172782	Nxt2	nuclear transport factor 2-like export factor 2
chr14_-_55735114	0.537	NM_177049	Jph4	junctophilin 4
chr5_-_137974398	0.524	NM_010312	Gnb2	guanine nucleotide binding protein (G protein), beta 2
chr2_+_25258568	0.521	NM_008721	Npdc1	neural proliferation, differentiation and control gene 1
chr11_+_113510855	0.518		Cog1	component of oligomeric golgi complex 1
chr9_+_20385734	0.515	NM_172919	Zfp846	zinc finger protein 846
chr9_+_37335673	0.508	NM_027102	Esam	endothelial cell-specific adhesion molecule
chr2_-_153051118	0.508	NM_198617	Tspyl3	TSPY-like 3
chr17_-_35372703	0.496	NM_010909	Nfkbil1	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr7_+_51565563	0.495	NM_001034115	Shank1	SH3/ankyrin domain gene 1
chr7_+_25292375	0.495		Zfp428	zinc finger protein 428
chr9_-_49607164	0.486	NM_001081445 NM_001113204 NM_010875	Ncam1	neural cell adhesion molecule 1
chr5_+_125956256	0.482		Aacs	acetoacetyl-CoA synthetase
chr11_-_115941908	0.482		Wbp2	WW domain binding protein 2
chr8_+_97605137	0.480		Katnb1	katanin p80 (WD40-containing) subunit B 1
chr4_+_144482722	0.478	NM_001172424	Dhrs3	dehydrogenase/reductase (SDR family) member 3
chr17_-_57184507	0.473		Slc25a23	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr13_-_67370003	0.472	NM_001001152	Zfp458	zinc finger protein 458
chr11_-_115138199	0.471	NM_007997	Fdxr	ferredoxin reductase
chr9_-_106794158	0.470		Manf	mesencephalic astrocyte-derived neurotrophic factor
chr4_+_43575487	0.467	NM_013497	Creb3	cAMP responsive element binding protein 3
chr15_+_103070840	0.466	NM_001039129 NM_010447	Hnrnpa1	heterogeneous nuclear ribonucleoprotein A1
chr11_+_74433092	0.465	NM_001013784	E130309D14Rik	RIKEN cDNA E130309D14 gene
chr8_+_75170609	0.460	NM_176940	Nwd1	NACHT and WD repeat domain containing 1
chr2_-_113669243	0.459	NM_009162	Scg5	secretogranin V
chr11_+_3352465	0.456		8430429K09Rik	RIKEN cDNA 8430429K09 gene
chr10_-_80477630	0.455	NM_010319	Gng7	guanine nucleotide binding protein (G protein), gamma 7
chr11_+_79404713	0.454	NM_175543	Rab11fip4	RAB11 family interacting protein 4 (class II)
chr5_-_143084635	0.453		Mmd2	monocyte to macrophage differentiation-associated 2
chr11_-_42134509	0.451		Gabra6	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6
chrX_-_61530035	0.451		Slitrk4	SLIT and NTRK-like family, member 4
chrX_+_117040804	0.437	NM_053114	Pabpc5	poly(A) binding protein, cytoplasmic 5
chr11_+_121296252	0.435	NM_001038699 NM_022014	Fn3k	fructosamine 3 kinase
chrM_+_11812	0.432
chr5_-_69732915	0.430	NM_175519	Kctd8	potassium channel tetramerisation domain containing 8
chr1_-_173152634	0.427	NM_001037170	Tomm40l	translocase of outer mitochondrial membrane 40 homolog-like (yeast)
chr17_-_27702625	0.426	NM_001002895	AI413582	expressed sequence AI413582
chr7_+_52897090	0.425		Mamstr	MEF2 activating motif and SAP domain containing transcriptional regulator
chr11_+_94797565	0.423	NM_007742	Col1a1	collagen, type I, alpha 1
chr15_+_3976598	0.420		Oxct1	3-oxoacid CoA transferase 1
chr8_-_125566133	0.418		Ankrd11	ankyrin repeat domain 11
chr1_+_165859920	0.417		Scyl3	SCY1-like 3 (S. cerevisiae)
chr19_+_8915018	0.415		Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr11_+_116976475	0.415	NM_001166506 NM_001166507 NM_028777	Sec14l1	SEC14-like 1 (S. cerevisiae)
chr8_-_83404377	0.413	NM_021356	Gab1	growth factor receptor bound protein 2-associated protein 1
chr8_-_125565896	0.409	NM_001081379	Ankrd11	ankyrin repeat domain 11
chr2_+_119698245	0.405		Mga	MAX gene associated
chr2_+_71819264	0.394	NM_019688	Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4
chr14_-_70689083	0.392	NM_008915	Ppp3cc	protein phosphatase 3, catalytic subunit, gamma isoform
chr7_+_139158135	0.392	NM_173410	Gpr26	G protein-coupled receptor 26
chr3_+_105508375	0.390	NM_001163356	6530418L21Rik	RIKEN cDNA 6530418L21 gene
chr5_+_125956205	0.390		Aacs	acetoacetyl-CoA synthetase
chr10_+_81096440	0.390		Ankrd24	ankyrin repeat domain 24

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
14.62	1.35e-10	GO:0019226	transmission of nerve impulse
14.62	1.35e-10	GO:0035637	multicellular organismal signaling
11.95	2.07e-09	GO:0007267	cell-cell signaling
15.83	3.10e-09	GO:0007268	synaptic transmission
8.26	6.04e-08	GO:0007154	cell communication
21.44	1.11e-06	GO:0007611	learning or memory
20.17	1.80e-06	GO:0050890	cognition
9.28	3.26e-05	GO:0007610	behavior
15.47	1.08e-04	GO:0006820	anion transport
21.72	1.09e-04	GO:0015698	inorganic anion transport
3.01	2.76e-04	GO:0006810	transport
2.96	3.67e-04	GO:0051234	establishment of localization
127.54	4.60e-04	GO:0043092	L-amino acid import
113.37	6.89e-04	GO:0043090	amino acid import
2.62	1.64e-03	GO:0051179	localization
18.70	2.36e-03	GO:0006836	neurotransmitter transport
60.03	5.48e-03	GO:0015800	acidic amino acid transport
10.64	6.91e-03	GO:0050804	regulation of synaptic transmission
9.87	1.06e-02	GO:0051969	regulation of transmission of nerve impulse
20.63	1.44e-02	GO:0006821	chloride transport
2.98	1.61e-02	GO:0050877	neurological system process
9.08	1.68e-02	GO:0031644	regulation of neurological system process
2.82	1.81e-02	GO:0003008	system process
4.47	2.20e-02	GO:0006811	ion transport
35.19	2.87e-02	GO:0015807	L-amino acid transport
113.37	4.42e-02	GO:0051938	L-glutamate import

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
7.98	5.62e-07	GO:0043005	neuron projection
8.57	1.08e-06	GO:0045202	synapse
10.58	2.97e-06	GO:0043025	neuronal cell body
10.08	4.68e-06	GO:0044297	cell body
9.21	5.08e-05	GO:0044456	synapse part
59.16	6.01e-05	GO:0043209	myelin sheath
7.48	2.84e-04	GO:0044463	cell projection part
12.69	7.87e-04	GO:0045211	postsynaptic membrane
4.22	8.40e-04	GO:0042995	cell projection
72.88	9.16e-04	GO:0048786	presynaptic active zone
1.99	1.05e-03	GO:0016021	integral to membrane
9.17	1.10e-03	GO:0030424	axon
1.94	1.79e-03	GO:0031224	intrinsic to membrane
8.37	1.98e-03	GO:0030425	dendrite
12.90	4.46e-03	GO:0033267	axon part
1.75	1.20e-02	GO:0044425	membrane part
1.63	1.29e-02	GO:0016020	membrane
97.17	1.92e-02	GO:0043218	compact myelin
20.42	4.58e-02	GO:0034707	chloride channel complex
61.84	4.98e-02	GO:0060076	excitatory synapse

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
14.91	2.85e-04	GO:0008509	anion transmembrane transporter activity
4.94	3.67e-04	GO:0022857	transmembrane transporter activity
5.02	8.66e-04	GO:0022891	substrate-specific transmembrane transporter activity
5.25	1.59e-03	GO:0015075	ion transmembrane transporter activity
4.03	2.93e-03	GO:0005215	transporter activity
4.38	3.10e-03	GO:0022892	substrate-specific transporter activity
21.27	3.63e-03	GO:0005230	extracellular ligand-gated ion channel activity
40.82	5.20e-03	GO:0015296	anion:cation symporter activity
18.40	6.43e-03	GO:0015294	solute:cation symporter activity
12.73	2.69e-02	GO:0015276	ligand-gated ion channel activity
12.73	2.69e-02	GO:0022834	ligand-gated channel activity
11.35	4.16e-02	GO:0015293	symporter activity
61.84	4.58e-02	GO:0016595	glutamate binding