• All motifs sorted by activity significance
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• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: KLF12.p2

Z-value: 2.318

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Top targets:

Promoter	Score	Refseq	Gene	Description
chr10_+_75398588	15.797		Chchd10	coiled-coil-helix-coiled-coil-helix domain containing 10
chr8_-_108467294	14.294	NM_008490	Lcat	lecithin cholesterol acyltransferase
chr10_-_108447894	12.063		Syt1	synaptotagmin I
chr10_-_108447996	11.293		Syt1	synaptotagmin I
chr8_-_89996474	11.240	NM_019626	Cbln1	cerebellin 1 precursor protein
chr10_-_108448003	9.744		Syt1	synaptotagmin I
chr1_-_83404659	9.587	NM_172430	Sphkap	SPHK1 interactor, AKAP domain containing
chr8_-_89996089	9.308		Cbln1	cerebellin 1 precursor protein
chr4_-_63707964	8.731		Tnc	tenascin C
chr6_+_103461323	8.003		Chl1	cell adhesion molecule with homology to L1CAM
chr2_-_25325248	7.688	NM_008963	Ptgds	prostaglandin D2 synthase (brain)
chr10_-_108447674	7.680	NM_009306	Syt1	synaptotagmin I
chr16_+_41533317	7.373	NM_175548	Lsamp	limbic system-associated membrane protein
chr2_+_118605431	7.171	NM_170593	Disp2	dispatched homolog 2 (Drosophila)
chr9_-_107134182	6.664	NM_153413	Dock3	dedicator of cyto-kinesis 3
chr7_-_86293852	6.471	NM_001045489 NM_008594	Mfge8	milk fat globule-EGF factor 8 protein
chr11_+_3414884	6.373		Selm	selenoprotein M
chr1_+_75502181	6.341		Obsl1	obscurin-like 1
chr8_+_124254462	6.298	NM_020605	Jph3	junctophilin 3
chr10_-_49508472	6.145	NM_001111268 NM_010349	Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)
chr15_-_78236262	6.095	NM_009437	Tst	thiosulfate sulfurtransferase, mitochondrial
chr8_-_70342105	5.919	NM_027626	Psd3	pleckstrin and Sec7 domain containing 3
chr10_+_75716647	5.897		S100b	S100 protein, beta polypeptide, neural
chrX_+_7496899	5.880	NM_013892	Pcsk1n	proprotein convertase subtilisin/kexin type 1 inhibitor
chr6_+_103460955	5.858		Chl1	cell adhesion molecule with homology to L1CAM
chr4_-_49858561	5.774		Grin3a	glutamate receptor ionotropic, NMDA3A
chr2_+_134611879	5.725	NM_001145830 NM_019677	Plcb1	phospholipase C, beta 1
chr11_-_69419419	5.671	NM_013415	Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr8_+_56040445	5.643		Gpm6a	glycoprotein m6a
chr7_+_86418127	5.555	NM_018811	Abhd2	abhydrolase domain containing 2
chr12_-_4848240	5.449	NM_016863	Fkbp1b	FK506 binding protein 1b
chr2_+_16277963	5.330		Plxdc2	plexin domain containing 2
chr2_+_164773719	5.098	NM_013599	Mmp9	matrix metallopeptidase 9
chr7_+_89319717	5.094	NM_017400	Sh3gl3	SH3-domain GRB2-like 3
chr9_+_27598853	5.043	NM_177906	Opcml	opioid binding protein/cell adhesion molecule-like
chr7_-_26460180	5.028	NM_177102	Tmem91	transmembrane protein 91
chr14_+_70857227	4.988	NM_145981	Phyhip	phytanoyl-CoA hydroxylase interacting protein
chr5_-_38550627	4.976	NM_010942	Nsg1	neuron specific gene family member 1
chr18_-_43059156	4.969		Ppp2r2b	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr1_-_137584672	4.816		Nav1	neuron navigator 1
chr7_-_26460133	4.796		Tmem91	transmembrane protein 91
chr7_-_31836457	4.672	NM_022007	Fxyd7	FXYD domain-containing ion transport regulator 7
chr10_-_61802889	4.632	NM_001146100	Hk1	hexokinase 1
chr6_-_18464737	4.626		Cttnbp2	cortactin binding protein 2
chr7_+_89319681	4.608		Sh3gl3	SH3-domain GRB2-like 3
chr1_-_175297778	4.547	NM_053199	Cadm3	cell adhesion molecule 3
chr6_-_85283412	4.418	NM_178639	Sfxn5	sideroflexin 5
chr2_+_156246644	4.408	NM_001003815 NM_013510	Epb4.1l1	erythrocyte protein band 4.1-like 1
chr2_+_134611931	4.408		Plcb1	phospholipase C, beta 1
chr10_+_90039435	4.334	NM_001177396 NM_001177398 NM_181398	Ipw Anks1b	imprinted gene in the Prader-Willi syndrome region ankyrin repeat and sterile alpha motif domain containing 1B
chr8_+_56040211	4.321		Gpm6a	glycoprotein m6a
chr1_+_59970358	4.315		Fam117b	family with sequence similarity 117, member B
chr1_-_137064124	4.310	NM_134438	Gpr37l1	G protein-coupled receptor 37-like 1
chr10_+_75716580	4.287	NM_009115	S100b	S100 protein, beta polypeptide, neural
chr12_+_87762593	4.222	NM_011934	Esrrb	estrogen related receptor, beta
chr11_+_68902025	4.212	NM_009497	Vamp2	vesicle-associated membrane protein 2
chr4_+_151712739	4.199	NM_001081376 NM_029216	Chd5	chromodomain helicase DNA binding protein 5
chr2_-_25316432	4.163		BC029214	cDNA sequence BC029214
chr2_-_42508486	4.134		Lrp1b	low density lipoprotein-related protein 1B (deleted in tumors)
chr11_+_98603186	4.133	NM_178060	Thra	thyroid hormone receptor alpha
chr2_-_79296732	4.119	NM_010894	Neurod1	neurogenic differentiation 1
chr5_+_58109278	4.119		Pcdh7	protocadherin 7
chr18_+_35020859	4.037	NM_007913	Egr1	early growth response 1
chr16_+_49855691	4.016	NM_010581	Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr12_+_110783786	3.999		Meg3	maternally expressed 3
chr8_-_112692071	3.989	NM_007586	Calb2	calbindin 2
chr6_-_85452851	3.979	NM_001001160	Fbxo41	F-box protein 41
chrX_+_97963061	3.927	NM_001177778 NM_016747	Dlg3	discs, large homolog 3 (Drosophila)
chr4_+_97248556	3.926	NM_001122952	Nfia D130039L10Rik	nuclear factor I/A RIKEN cDNA D130039L10 gene
chr17_+_34766489	3.905	NM_030890	Prrt1	proline-rich transmembrane protein 1
chr3_+_75878452	3.862	NM_178673	Fstl5	follistatin-like 5
chr8_+_56040193	3.811		Gpm6a	glycoprotein m6a
chr4_+_147534729	3.800		Fbxo2	F-box protein 2
chr5_+_43625165	3.796		Cpeb2	cytoplasmic polyadenylation element binding protein 2
chr17_+_81343933	3.792	NM_026516	Tmem178	transmembrane protein 178
chr10_+_40069255	3.792		Cdk19	cyclin-dependent kinase 19
chr4_+_130348406	3.762	NM_011520	Sdc3	syndecan 3
chr7_+_86418082	3.752		Abhd2	abhydrolase domain containing 2
chr16_+_91270009	3.746	NM_016968	Olig1	oligodendrocyte transcription factor 1
chr10_+_106708886	3.719	NM_001033223 NM_001039354	Lin7a	lin-7 homolog A (C. elegans)
chr2_-_17652669	3.675	NM_028757	Nebl	nebulette
chr7_+_28438881	3.667	NM_028417	Ttc9b	tetratricopeptide repeat domain 9B
chr8_-_87324043	3.655	NM_001081982 NM_010906	Nfix	nuclear factor I/X
chr11_-_30168153	3.617		Spnb2	spectrin beta 2
chr11_-_64976408	3.526	NM_001099288 NM_175003	Arhgap44	Rho GTPase activating protein 44
chr15_+_76490995	3.488	NM_010630	Kifc2	kinesin family member C2
chr11_+_68901989	3.470		Vamp2	vesicle-associated membrane protein 2
chr15_+_12047769	3.412		Zfr	zinc finger RNA binding protein
chr3_+_31048841	3.356	NM_008770	Cldn11	claudin 11
chr18_-_43058544	3.345	NM_027531	Ppp2r2b	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr11_-_69651218	3.320		Nlgn2	neuroligin 2
chr2_+_156301543	3.314	NM_001006664	Epb4.1l1	erythrocyte protein band 4.1-like 1
chr11_-_95936914	3.302	NM_001161419 NM_007506	Atp5g1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr19_+_4510471	3.282	NM_001162946	Pcx	pyruvate carboxylase
chr5_-_106887469	3.278		Barhl2	BarH-like 2 (Drosophila)
chr10_-_61802814	3.232		Hk1	hexokinase 1
chr14_-_55531726	3.221	NM_021551	Slc22a17	solute carrier family 22 (organic cation transporter), member 17
chr10_+_89336253	3.214	NM_001128086	Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr9_+_37175190	3.157	NM_175189	Hepacam	hepatocyte cell adhesion molecule
chr13_-_12199109	3.150	NM_023868	Ryr2	ryanodine receptor 2, cardiac
chr4_-_151235758	3.149		Camta1	calmodulin binding transcription activator 1
chr8_+_56040553	3.059		Gpm6a	glycoprotein m6a
chr18_+_82723920	3.024		Mbp	myelin basic protein
chr17_-_24856893	3.006		Snhg9	small nucleolar RNA host gene (non-protein coding) 9
chr5_-_8367951	3.001	NM_001007220 NM_001007221 NM_001098225	Adam22	a disintegrin and metallopeptidase domain 22
chr13_+_55050729	2.995	NM_153131	Unc5a	unc-5 homolog A (C. elegans)
chr16_-_28753276	2.982	NM_010199	Fgf12	fibroblast growth factor 12
chr17_+_24607348	2.968	NM_025954	Pgp	phosphoglycolate phosphatase
chr13_+_109906361	2.962		Pde4d	phosphodiesterase 4D, cAMP specific
chr11_-_60166321	2.960		Tom1l2	target of myb1-like 2 (chicken)
chr2_+_134611953	2.953		Plcb1	phospholipase C, beta 1
chr4_-_68615283	2.948		Dbc1	deleted in bladder cancer 1 (human)
chr8_+_89996675	2.941		Gm2694	predicted gene 2694
chr16_-_85120798	2.931		App	amyloid beta (A4) precursor protein
chr10_-_63552994	2.926	NM_178678	Lrrtm3	leucine rich repeat transmembrane neuronal 3
chr4_+_147534776	2.903	NM_176848	Fbxo2	F-box protein 2
chrX_-_132738383	2.878	NM_177919	Tceal5	transcription elongation factor A (SII)-like 5
chr5_-_138041861	2.875		Mospd3	motile sperm domain containing 3
chr15_+_54402914	2.873	NM_178920	Mal2	mal, T-cell differentiation protein 2
chr6_+_115084919	2.870	NM_001111015 NM_013681	Syn2	synapsin II
chr5_-_77524256	2.855	NM_001159900 NM_001159901	Hopx	HOP homeobox
chr2_+_16277924	2.844	NM_026162	Plxdc2	plexin domain containing 2
chr8_+_89996742	2.826		Gm2694	predicted gene 2694
chr2_-_119096952	2.811	NM_145530	Rhov	ras homolog gene family, member V
chr14_+_66963139	2.810	NM_019675	Stmn4	stathmin-like 4
chr1_-_164408123	2.803		Dnm3	dynamin 3
chr2_-_130867226	2.786		Gfra4	glial cell line derived neurotrophic factor family receptor alpha 4
chr2_-_130249983	2.747	NM_178762	Fam113a	family with sequence similarity 113, member A
chr9_-_30957394	2.733
chr15_+_4325490	2.714	NM_177355	Plcxd3	phosphatidylinositol-specific phospholipase C, X domain containing 3
chr19_-_58935417	2.706		Hspa12a	heat shock protein 12A
chrX_-_20498021	2.699	NM_001110780 NM_013680	Syn1	synapsin I
chr11_-_61267383	2.682	NM_009548	Rnf112	ring finger protein 112
chr14_-_119498586	2.679	NM_001081252	Uggt2	UDP-glucose glycoprotein glucosyltransferase 2
chr11_+_3414792	2.671		Selm	selenoprotein M
chr10_+_98377759	2.668	NM_026482	Atp2b1	ATPase, Ca++ transporting, plasma membrane 1
chr12_+_110784600	2.643		Meg3	maternally expressed 3
chr2_+_55288297	2.642		Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3
chr10_+_86241749	2.637	NM_175331	Nt5dc3	5'-nucleotidase domain containing 3
chr19_+_53214934	2.632	NM_001164099 NM_001164101	Add3	adducin 3 (gamma)
chr1_+_87942437	2.631	NM_001144992 NM_001144993	2810459M11Rik	RIKEN cDNA 2810459M11 gene
chr2_-_153051118	2.611	NM_198617	Tspyl3	TSPY-like 3
chr5_-_124053691	2.610		Clip1	CAP-GLY domain containing linker protein 1
chr1_-_164408008	2.572		Dnm3	dynamin 3
chr11_+_105451296	2.570	NM_181071	Tanc2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr8_+_109555200	2.564	NM_126165	Vps4a	vacuolar protein sorting 4a (yeast)
chr7_-_20284370	2.544		Apoe	apolipoprotein E
chr11_-_75609557	2.526	NM_007873	Doc2b	double C2, beta
chrX_-_98615096	2.518	NM_001177985 NM_001177986	Zmym3	zinc finger, MYM-type 3
chr2_-_73498303	2.511	NM_001166604 NM_175752	Chn1	chimerin (chimaerin) 1
chr6_-_55631085	2.501		Neurod6	neurogenic differentiation 6
chr11_+_49715292	2.493	NM_029004	Rasgef1c	RasGEF domain family, member 1C
chr17_-_35971913	2.479		Tubb5	tubulin, beta 5
chr18_+_82723907	2.478		Mbp	myelin basic protein
chr4_-_82151657	2.476		Nfib	nuclear factor I/B
chr1_+_174051888	2.471
chr9_-_117161234	2.465		Rbms3	RNA binding motif, single stranded interacting protein
chrX_-_131745187	2.461	NM_025355	Tceal6	transcription elongation factor A (SII)-like 6
chrX_-_149078963	2.461		Shroom2	shroom family member 2
chr10_+_84849558	2.455	NM_028709	Btbd11	BTB (POZ) domain containing 11
chr2_-_25174498	2.454		Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr6_-_18464792	2.438	NM_080285	Cttnbp2	cortactin binding protein 2
chr14_-_22668093	2.431	NM_026965	Comtd1	catechol-O-methyltransferase domain containing 1
chr11_+_120582777	2.409	NM_133223	Rac3	RAS-related C3 botulinum substrate 3
chr12_-_77811119	2.408		Spnb1	spectrin beta 1
chr16_-_88290458	2.387	NM_010348 NM_146072	Grik1	glutamate receptor, ionotropic, kainate 1
chr7_+_94735020	2.387		C030032F19Rik	RIKEN cDNA C030032F19 gene
chr11_-_59005394	2.377	NM_008193	Guk1	guanylate kinase 1
chr18_-_32109233	2.375	NM_001025381	Gpr17	G protein-coupled receptor 17
chr2_+_155970003	2.366	NM_025946	Romo1	reactive oxygen species modulator 1
chr1_+_145487825	2.361	NM_020025	B3galt2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr5_+_22252006	2.343	NM_001081231 NM_029990	Lhfpl3	lipoma HMGIC fusion partner-like 3
chr16_+_49855786	2.326		Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr4_+_144482979	2.325	NM_011303	Dhrs3	dehydrogenase/reductase (SDR family) member 3
chr8_-_72758007	2.324		Armc6	armadillo repeat containing 6
chr11_-_118770859	2.319		Rbfox3	RNA binding protein, fox-1 homolog (C. elegans) 3
chr4_-_151235861	2.308	NM_001081557 NM_001195565	Camta1	calmodulin binding transcription activator 1
chr3_-_87804062	2.304		Bcan	brevican
chr18_-_62071494	2.299	NM_001164491	Ablim3	actin binding LIM protein family, member 3
chr14_+_68701838	2.293	NM_010910	Nefl	neurofilament, light polypeptide
chr9_-_112137285	2.280	NM_001177619	Arpp21	cyclic AMP-regulated phosphoprotein, 21
chr11_+_3414983	2.278		Selm	selenoprotein M
chr12_+_110783593	2.273		Meg3	maternally expressed 3
chr1_-_77511577	2.262		Epha4	Eph receptor A4
chr6_+_113554785	2.242		6720456B07Rik	RIKEN cDNA 6720456B07 gene
chr6_-_124718354	2.222		Eno2	enolase 2, gamma neuronal
chr1_-_175297624	2.215		Cadm3	cell adhesion molecule 3
chr11_-_116515361	2.213		Cygb	cytoglobin
chr17_-_27702625	2.209	NM_001002895	AI413582	expressed sequence AI413582
chr5_+_37259780	2.209	NM_172994	Ppp2r2c	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr8_+_113245378	2.203	NM_198625	Mtss1l	metastasis suppressor 1-like
chr8_-_125760103	2.198	NM_030176	Spata2L	spermatogenesis associated 2-like
chr4_-_86876311	2.197		Slc24a2	solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr8_-_86095743	2.191
chr6_+_113554717	2.189	NM_133937	6720456B07Rik	RIKEN cDNA 6720456B07 gene
chr4_-_104782444	2.183	NM_178143	Prkaa2	protein kinase, AMP-activated, alpha 2 catalytic subunit
chr5_+_98683202	2.181	NM_010203	Fgf5	fibroblast growth factor 5
chr3_-_81949667	2.179	NM_021896	Gucy1a3	guanylate cyclase 1, soluble, alpha 3
chr11_+_69652013	2.178	NM_026982	1810027O10Rik	RIKEN cDNA 1810027O10 gene
chr16_-_28753298	2.171		Fgf12	fibroblast growth factor 12

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.77	6.62e-08	GO:0051179	localization
1.76	6.01e-06	GO:0051234	establishment of localization
2.25	8.64e-06	GO:0007399	nervous system development
1.75	1.03e-05	GO:0006810	transport
2.69	6.76e-05	GO:0007155	cell adhesion
2.67	8.38e-05	GO:0022610	biological adhesion
23.38	8.51e-05	GO:0035235	ionotropic glutamate receptor signaling pathway
3.29	2.78e-04	GO:0019226	transmission of nerve impulse
3.29	2.78e-04	GO:0035637	multicellular organismal signaling
2.36	3.36e-04	GO:0006811	ion transport
8.77	8.45e-04	GO:0007269	neurotransmitter secretion
3.49	1.00e-03	GO:0007268	synaptic transmission
2.26	1.35e-03	GO:0022008	neurogenesis
12.00	1.56e-03	GO:0007215	glutamate signaling pathway
1.79	1.79e-03	GO:0065008	regulation of biological quality
6.13	2.14e-03	GO:0048167	regulation of synaptic plasticity
2.81	8.00e-03	GO:0007610	behavior
2.67	8.12e-03	GO:0006873	cellular ion homeostasis
2.69	1.08e-02	GO:0007267	cell-cell signaling
2.18	1.08e-02	GO:0048699	generation of neurons
5.18	1.13e-02	GO:0006836	neurotransmitter transport
4.72	1.18e-02	GO:0003001	generation of a signal involved in cell-cell signaling
4.72	1.18e-02	GO:0023061	signal release
1.26	1.23e-02	GO:0050794	regulation of cellular process
2.36	1.27e-02	GO:0006812	cation transport
2.60	1.29e-02	GO:0055082	cellular chemical homeostasis
2.53	1.38e-02	GO:0050801	ion homeostasis
1.24	1.71e-02	GO:0065007	biological regulation
1.96	2.09e-02	GO:0051641	cellular localization
4.13	2.19e-02	GO:0050890	cognition
1.57	2.50e-02	GO:0048731	system development
2.28	2.50e-02	GO:0048878	chemical homeostasis
6.60	3.29e-02	GO:0009743	response to carbohydrate stimulus
2.41	3.41e-02	GO:0030001	metal ion transport
1.56	3.81e-02	GO:0048519	negative regulation of biological process
4.99	4.09e-02	GO:0050770	regulation of axonogenesis
1.24	4.30e-02	GO:0050789	regulation of biological process
12.61	4.33e-02	GO:0060081	membrane hyperpolarization
19.05	4.39e-02	GO:0007263	nitric oxide mediated signal transduction
1.59	4.78e-02	GO:0048523	negative regulation of cellular process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
3.78	3.54e-11	GO:0045202	synapse
2.52	5.54e-10	GO:0000267	cell fraction
1.70	8.30e-09	GO:0071944	cell periphery
3.17	1.87e-08	GO:0043005	neuron projection
1.67	6.63e-08	GO:0005886	plasma membrane
2.50	2.80e-07	GO:0005626	insoluble fraction
3.73	3.01e-07	GO:0044456	synapse part
2.52	4.80e-07	GO:0005624	membrane fraction
1.15	2.13e-06	GO:0005623	cell
1.15	2.13e-06	GO:0044464	cell part
3.46	1.03e-05	GO:0043025	neuronal cell body
3.61	1.55e-05	GO:0030425	dendrite
1.31	2.42e-05	GO:0016020	membrane
3.30	2.70e-05	GO:0044297	cell body
2.08	1.46e-04	GO:0042995	cell projection
1.79	2.14e-04	GO:0044459	plasma membrane part
1.27	5.13e-04	GO:0005737	cytoplasm
2.39	6.49e-04	GO:0030054	cell junction
13.54	7.71e-04	GO:0008328	ionotropic glutamate receptor complex
4.41	8.64e-04	GO:0019717	synaptosome
1.79	2.86e-03	GO:0005856	cytoskeleton
1.28	3.89e-03	GO:0044425	membrane part
1.33	5.57e-03	GO:0044444	cytoplasmic part
3.73	6.04e-03	GO:0045211	postsynaptic membrane
2.69	6.74e-03	GO:0005625	soluble fraction
7.50	8.11e-03	GO:0042734	presynaptic membrane
2.51	8.91e-03	GO:0044463	cell projection part
1.17	1.08e-02	GO:0005622	intracellular
4.76	2.63e-02	GO:0030426	growth cone
25.72	2.88e-02	GO:0008091	spectrin
4.65	3.18e-02	GO:0014069	postsynaptic density
1.16	3.47e-02	GO:0044424	intracellular part
4.59	3.48e-02	GO:0030427	site of polarized growth

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.56	3.34e-10	GO:0005515	protein binding
1.23	8.58e-05	GO:0005488	binding
2.11	1.82e-04	GO:0005215	transporter activity
2.20	2.92e-04	GO:0022892	substrate-specific transporter activity
4.88	3.63e-04	GO:0005516	calmodulin binding
2.87	8.42e-04	GO:0022838	substrate-specific channel activity
2.79	1.47e-03	GO:0015267	channel activity
2.78	1.54e-03	GO:0022803	passive transmembrane transporter activity
2.82	1.85e-03	GO:0005216	ion channel activity
2.18	2.08e-03	GO:0022891	substrate-specific transmembrane transporter activity
2.24	3.54e-03	GO:0015075	ion transmembrane transporter activity
2.07	3.87e-03	GO:0022857	transmembrane transporter activity
2.39	6.89e-03	GO:0005509	calcium ion binding
2.37	8.23e-03	GO:0008092	cytoskeletal protein binding
2.41	8.35e-03	GO:0008324	cation transmembrane transporter activity
3.08	8.79e-03	GO:0005261	cation channel activity
11.91	1.49e-02	GO:0004970	ionotropic glutamate receptor activity
8.87	1.56e-02	GO:0008066	glutamate receptor activity
6.82	2.16e-02	GO:0017048	Rho GTPase binding
15.59	2.81e-02	GO:0043274	phospholipase binding
2.78	3.31e-02	GO:0022836	gated channel activity
1.93	3.70e-02	GO:0019899	enzyme binding
1.83	4.03e-02	GO:0005102	receptor binding