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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: LHX3,4.p2

Z-value: 0.545

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Top targets:

Promoter	Score	Refseq	Gene	Description
chr7_-_111001598	14.351	NM_008221	Hbb-y	hemoglobin Y, beta-like embryonic chain
chr7_-_56892061	5.838	NM_001005232	Dbx1	developing brain homeobox 1
chr12_+_30219982	3.932		Myt1l	myelin transcription factor 1-like
chr9_-_71743854	3.041		Tcf12	transcription factor 12
chr10_+_101621491	1.869	NM_001162368	Mgat4c 4930402I19Rik	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative) RIKEN cDNA 4930402I19 gene
chr15_-_103045710	1.826	NM_001110216 NM_007626	Cbx5	chromobox homolog 5 (Drosophila HP1a)
chr14_-_111154292	1.791	NM_175499	Slitrk6	SLIT and NTRK-like family, member 6
chr12_+_30219769	1.751	NM_001093776	Myt1l	myelin transcription factor 1-like
chr2_+_61642509	1.666	NM_009322	Tbr1	T-box brain gene 1
chr9_+_96159123	1.553	NM_001184709	Tfdp2	transcription factor Dp 2
chr15_-_56526052	1.459	NM_008216	Has2	hyaluronan synthase 2
chr1_-_42749940	1.408		2610017I09Rik	RIKEN cDNA 2610017I09 gene
chr17_+_34729159	1.392		Pbx2	pre B-cell leukemia transcription factor 2
chr9_+_96159666	1.264	NM_001184710 NM_001184711	Tfdp2	transcription factor Dp 2
chr2_-_65405546	1.182	NM_018732	Scn3a	sodium channel, voltage-gated, type III, alpha
chr3_-_49561168	0.994	NM_130448	Pcdh18	protocadherin 18
chr15_-_76983985	0.977	NM_001110828 NM_001110829 NM_001110830	Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr3_+_127336055	0.943	NM_009718	Neurog2	neurogenin 2
chr1_-_128634766	0.942		Nckap5	NCK-associated protein 5
chr6_+_38331516	0.936	NM_153600	Ttc26	tetratricopeptide repeat domain 26
chrX_-_103207106	0.934	NM_001190409 NM_025952	Magt1	magnesium transporter 1
chr6_+_37820779	0.920	NM_145076	Trim24	tripartite motif-containing 24
chr4_-_109960078	0.891	NM_001038698	Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr3_+_17695743	0.854		6430547I21Rik	RIKEN cDNA 6430547I21 gene
chr3_-_66100663	0.849	NM_145820	Veph1	ventricular zone expressed PH domain homolog 1 (zebrafish)
chr13_-_76081244	0.830	NM_028493	Rhobtb3	Rho-related BTB domain containing 3
chr5_+_19413335	0.807	NM_001170745 NM_015823	Magi2	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_-_86352170	0.783	NM_011839	Mab21l2	mab-21-like 2 (C. elegans)
chr17_+_78907402	0.779	NM_001197028 NM_028813	Vit	vitrin
chr14_+_65885454	0.771	NM_015795	Fbxo16	F-box protein 16
chr7_+_108966826	0.759	NM_008887	Phox2a	paired-like homeobox 2a
chrY_+_347036	0.749	NM_012011	Eif2s3y	eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr11_+_62389048	0.732		Trpv2	transient receptor potential cation channel, subfamily V, member 2
chr14_-_109313298	0.717		Slitrk1	SLIT and NTRK-like family, member 1
chr4_-_33010429	0.636	NM_001012450 NM_080471	Ankrd6	ankyrin repeat domain 6
chr9_+_108241599	0.591	NM_008160	Gpx1	glutathione peroxidase 1
chr13_-_54652983	0.577		4833439L19Rik	RIKEN cDNA 4833439L19 gene
chr1_-_173957407	0.575		Vangl2	vang-like 2 (van gogh, Drosophila)
chrX_-_6765768	0.558	NM_016691	Clcn5	chloride channel 5
chr12_-_42212538	0.544		Lrrn3	leucine rich repeat protein 3, neuronal
chr12_-_99816091	0.541	NM_029911	Kcnk10	potassium channel, subfamily K, member 10
chr14_+_75855788	0.540	NM_001128093	Siah3	seven in absentia homolog 3 (Drosophila)
chr5_-_5265981	0.539		Cdk14	cyclin-dependent kinase 14
chr7_+_16633755	0.535		2010004M13Rik	RIKEN cDNA 2010004M13 gene
chr2_+_22924699	0.519		Acbd5	acyl-Coenzyme A binding domain containing 5
chr11_+_87032504	0.497		Trim37	tripartite motif-containing 37
chr12_+_25659777	0.492	NM_001081378	Kidins220	kinase D-interacting substrate 220
chr3_-_84024766	0.482	NM_030706	Trim2	tripartite motif-containing 2
chrX_-_147091911	0.472	NM_001002272 NM_019548	Tro	trophinin
chr18_+_37854011	0.468	NM_033588	Pcdhga5	protocadherin gamma subfamily A, 5
chr2_-_28771940	0.467	NM_019446 NM_001164186	Barhl1	BarH-like 1 (Drosophila)
chr6_+_5340417	0.462		Asb4	ankyrin repeat and SOCS box-containing 4
chr9_-_22064292	0.457	NM_181419	Zfp599	zinc finger protein 599
chr5_-_114292851	0.453		Coro1c	coronin, actin binding protein 1C
chr10_-_26095736	0.452		L3mbtl3	l(3)mbt-like 3 (Drosophila)
chr1_-_97564064	0.435		St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr10_-_127613494	0.433		Rbms2	RNA binding motif, single stranded interacting protein 2
chr17_-_32946797	0.420	NM_183177	Zfp811	zinc finger protein 811
chr6_+_103460834	0.416	NM_007697	Chl1	cell adhesion molecule with homology to L1CAM
chr3_+_122122640	0.416	NM_013867	Bcar3	breast cancer anti-estrogen resistance 3
chr3_+_66789621	0.415		Rsrc1	arginine/serine-rich coiled-coil 1
chr5_-_123271207	0.408		Anapc5	anaphase-promoting complex subunit 5
chr1_+_134088010	0.396	NM_001033250	Lemd1	LEM domain containing 1
chr3_+_32335072	0.389	NM_008839	Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr7_-_77511242	0.386		Nr2f2	nuclear receptor subfamily 2, group F, member 2
chr6_+_51494591	0.384		Snx10	sorting nexin 10
chr7_+_73194834	0.383		Pcsk6	proprotein convertase subtilisin/kexin type 6
chr6_-_128380651	0.374
chr2_+_35413977	0.371	NM_001114125	Dab2ip	disabled homolog 2 (Drosophila) interacting protein
chrX_+_90920450	0.369	NM_211138	Pcyt1b	phosphate cytidylyltransferase 1, choline, beta isoform
chr6_-_42660031	0.362		Fam115a	family with sequence similarity 115, member A
chr16_-_11220854	0.362		Gspt1	G1 to S phase transition 1
chr11_+_59120429	0.354	NM_139298	Wnt9a	wingless-type MMTV integration site 9A
chr1_+_12682572	0.350		Sulf1	sulfatase 1
chr7_+_74792295	0.349	NM_001168475 NM_001168476 NM_001168477 NM_025905	Ttc23	tetratricopeptide repeat domain 23
chr14_-_96918064	0.345	NM_053105	Klhl1	kelch-like 1 (Drosophila)
chr5_+_104631633	0.342	NM_016779	Dmp1	dentin matrix protein 1
chr1_-_135557925	0.340		Zc3h11a	zinc finger CCCH type containing 11A
chrX_+_166123130	0.337	NM_010797	Mid1	midline 1
chr3_-_115956312	0.336	NM_022427	Gpr88	G-protein coupled receptor 88
chr6_+_7505070	0.335	NM_009311	Tac1	tachykinin 1
chr11_+_85322997	0.334		Bcas3	breast carcinoma amplified sequence 3
chr2_+_174171943	0.334
chr14_-_71107810	0.330		Xpo7	exportin 7
chrX_+_103222548	0.330	NM_001109757 NM_009726	Atp7a	ATPase, Cu++ transporting, alpha polypeptide
chr11_+_57985140	0.319	NM_175001	Mrpl22	mitochondrial ribosomal protein L22
chr11_+_93905557	0.316		Spag9	sperm associated antigen 9
chr7_+_130267661	0.314		Tnrc6a	trinucleotide repeat containing 6a
chr8_+_42416046	0.306		Pcm1	pericentriolar material 1
chr13_+_21454688	0.305	NM_016684	Zscan12	zinc finger and SCAN domain containing 12
chr18_-_67020125	0.300	NM_016977	Mc4r	melanocortin 4 receptor
chr10_+_101621712	0.300	NM_001162369	Mgat4c	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr8_+_73282270	0.299
chr11_+_60351469	0.299		Alkbh5	alkB, alkylation repair homolog 5 (E. coli)
chr7_+_77510266	0.296		B130024G19Rik	RIKEN cDNA B130024G19 gene
chr3_+_125106995	0.294	NM_022565	Ndst4	N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr4_+_122731563	0.294		Trit1	tRNA isopentenyltransferase 1
chr15_-_24957039	0.293		Gm2824	predicted gene 2824
chr1_+_141398282	0.292	NM_031164	F13b	coagulation factor XIII, beta subunit
chr5_-_108026906	0.292	NM_001161738	Glmn	glomulin, FKBP associated protein
chr2_+_162760505	0.288
chr18_+_59222034	0.286	NM_001167925 NM_173759	A730017C20Rik	RIKEN cDNA A730017C20 gene
chr14_-_109313333	0.286		Slitrk1	SLIT and NTRK-like family, member 1
chr1_+_34364633	0.286		Dst	dystonin
chr17_-_34999068	0.285		Cfb	complement factor B
chr7_-_29678773	0.283		Actn4	actinin alpha 4
chr1_-_72330767	0.281	NM_023523	Pecr	peroxisomal trans-2-enoyl-CoA reductase
chr1_+_169528838	0.280		Rxrg	retinoid X receptor gamma
chr10_+_36226612	0.279	NM_001081208	Hs3st5	heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr9_-_44610921	0.278		Ttc36	tetratricopeptide repeat domain 36
chr13_-_76081343	0.276		Rhobtb3	Rho-related BTB domain containing 3
chr9_-_44611055	0.276		Ttc36	tetratricopeptide repeat domain 36
chr6_-_90611092	0.275		Iqsec1	IQ motif and Sec7 domain 1
chr9_+_21330620	0.273	NM_001198794 NM_206536	AB124611	cDNA sequence AB124611
chr16_-_55934909	0.272	NM_001159364 NM_001159365 NM_001159366 NM_028815	Cep97	centrosomal protein 97
chr10_-_102698899	0.272	NM_001163559 NM_029134	Lrriq1	leucine-rich repeats and IQ motif containing 1
chr6_+_51494521	0.270	NM_001127348 NM_028035	Snx10	sorting nexin 10
chr10_+_41249215	0.264
chr5_-_136384495	0.261
chr1_-_173957316	0.259	NM_033509	Vangl2	vang-like 2 (van gogh, Drosophila)
chr11_-_98862163	0.258		Top2a	topoisomerase (DNA) II alpha
chr18_+_65048630	0.258		Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like
chr4_+_95224197	0.257	NM_001113412	Fggy	FGGY carbohydrate kinase domain containing
chr2_+_110561733	0.254	NM_172979	Muc15	mucin 15
chr10_-_117252126	0.253
chr5_-_5265598	0.252		Cdk14	cyclin-dependent kinase 14
chr19_-_7501451	0.251		Rtn3	reticulon 3
chr4_-_116228531	0.249	NM_177670	Tmem69	transmembrane protein 69
chr5_-_149320857	0.247		Ubl3	ubiquitin-like 3
chr2_-_163450863	0.246		Serinc3	serine incorporator 3
chr2_+_153035426	0.241		Tm9sf4	transmembrane 9 superfamily protein member 4
chr12_+_73885063	0.240		Ppm1a	protein phosphatase 1A, magnesium dependent, alpha isoform
chr4_-_136158570	0.240	NM_133872	Kdm1a	lysine (K)-specific demethylase 1A
chrX_+_139997806	0.239	NM_008778	Pak3	p21 protein (Cdc42/Rac)-activated kinase 3
chr18_-_57134974	0.236	NM_029909	C330018D20Rik	RIKEN cDNA C330018D20 gene
chr13_-_4608352	0.235	NM_018859	Akr1e1	aldo-keto reductase family 1, member E1
chr7_-_35597470	0.234	NM_175140	Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr7_+_13615892	0.232		Trim28	tripartite motif-containing 28
chr4_+_98697606	0.231	NM_013913	Angptl3	angiopoietin-like 3
chr3_+_66023884	0.230		Ptx3	pentraxin related gene
chr2_+_152106052	0.229		Csnk2a1	casein kinase 2, alpha 1 polypeptide
chr14_-_109313447	0.227	NM_199065	Slitrk1	SLIT and NTRK-like family, member 1
chr10_+_19890580	0.227		1700026H06Rik	RIKEN cDNA 1700026H06 gene
chr19_-_25036047	0.227	NM_146097	Cbwd1	COBW domain containing 1
chr8_+_13869640	0.227	NM_181854	Zfp828	zinc finger protein 828
chr19_+_13439119	0.226	NM_146691	Olfr1467	olfactory receptor 1467
chr12_-_74147683	0.225		Six1	sine oculis-related homeobox 1 homolog (Drosophila)
chr12_+_10397567	0.223	NM_023697	Rdh14	retinol dehydrogenase 14 (all-trans and 9-cis)
chr17_-_45704908	0.218
chr15_+_34044603	0.216		Mtdh	metadherin
chr10_-_116786025	0.215		Cpsf6	cleavage and polyadenylation specific factor 6
chr8_-_55809700	0.212	NM_001172152	Wdr17	WD repeat domain 17
chr11_-_89280247	0.212	NM_172534	4932411E22Rik	RIKEN cDNA 4932411E22 gene
chr1_-_37973274	0.210	NM_001033427	Lyg2	lysozyme G-like 2
chr7_+_18830695	0.207	NM_153749	Mill1	MHC I like leukocyte 1
chr4_+_109015660	0.206	NM_001159964	Eps15	epidermal growth factor receptor pathway substrate 15
chr13_-_76155834	0.204	NM_178916 NM_001131068 NM_001131069	Rfesd	Rieske (Fe-S) domain containing
chr6_-_54543167	0.203		Fkbp14	FK506 binding protein 14
chr17_-_45707285	0.201		Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1
chr1_-_176851918	0.200		Grem2	gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr9_+_104472090	0.199	NM_028719	Cpne4	copine IV
chr16_-_20610796	0.199	NM_145939	Alg3	asparagine-linked glycosylation 3 homolog (yeast, alpha-1,3-mannosyltransferase)
chr14_+_27852148	0.199	NM_134437	Il17rd	interleukin 17 receptor D
chr4_+_43460181	0.198
chr3_+_31801595	0.198	NM_028231	Kcnmb2	potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr6_-_3444484	0.197	NM_178899	Hepacam2	HEPACAM family member 2
chr1_-_128727208	0.197	NM_001081756 NM_176957	Nckap5	NCK-associated protein 5
chr10_+_89280918	0.196		Uhrf1bp1l	UHRF1 (ICBP90) binding protein 1-like
chr3_-_103546233	0.193		Hipk1	homeodomain interacting protein kinase 1
chr4_+_45310018	0.192	NM_027266	Rg9mtd3	RNA (guanine-9-) methyltransferase domain containing 3
chr15_-_101573522	0.192	NM_019956	Krt71	keratin 71
chr12_+_111723922	0.190	NM_001081457 NM_001081458 NM_012023	Ppp2r5c	protein phosphatase 2, regulatory subunit B (B56), gamma isoform
chr7_-_20218609	0.189
chr2_+_65683823	0.189	NM_153409 NM_178634	Csrnp3	cysteine-serine-rich nuclear protein 3
chr13_-_84204320	0.188		LOC553095	hypothetical LOC553095
chr3_+_88342459	0.186		Mex3a	mex3 homolog A (C. elegans)
chr5_-_122907269	0.184		Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr9_+_78039786	0.183		Gsta4	glutathione S-transferase, alpha 4
chr12_+_60114357	0.181	NM_025656	Sip1	survival of motor neuron protein interacting protein 1
chr17_-_31266539	0.180	NM_011575	Tff3	trefoil factor 3, intestinal
chr11_+_115106897	0.179
chr17_+_12571494	0.178		Plg	plasminogen
chr2_+_109120894	0.178	NM_139303	Kif18a	kinesin family member 18A
chr1_+_12682510	0.176	NM_001198565 NM_001198566	Sulf1	sulfatase 1
chr15_-_10967722	0.174	NM_178717	Rxfp3	relaxin family peptide receptor 3
chr2_+_36086059	0.174		Ptgs1	prostaglandin-endoperoxide synthase 1
chrX_-_140367467	0.172	NM_001110222 NM_001110223 NM_001110224 NM_010025	Dcx	doublecortin
chr13_+_42776161	0.169		Phactr1	phosphatase and actin regulator 1
chr6_-_85894613	0.169		Dusp11	dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr9_-_82826139	0.167		Phip	pleckstrin homology domain interacting protein
chr12_+_91570569	0.167		Nrxn3	neurexin III
chr4_+_5726856	0.167		Fam110b	family with sequence similarity 110, member B
chr9_-_16182674	0.167	NM_001080814	Fat3	FAT tumor suppressor homolog 3 (Drosophila)
chr4_-_34754469	0.167		Zfp292	zinc finger protein 292
chr15_+_81575277	0.165	NM_001081016	Zc3h7b	zinc finger CCCH type containing 7B
chr17_-_74242984	0.165		Xdh	xanthine dehydrogenase
chr7_-_110976438	0.164		Hbb-b1	hemoglobin, beta adult major chain
chr9_-_39411708	0.163	NM_178737	AW551984	expressed sequence AW551984
chr12_-_32398730	0.162	NM_175191	Gpr22	G protein-coupled receptor 22
chr10_+_23614493	0.162	NM_011704	Vnn1	vanin 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
5.05	2.84e-03	GO:0006355	regulation of transcription, DNA-dependent
4.95	3.29e-03	GO:0051252	regulation of RNA metabolic process
4.64	5.32e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
4.53	6.38e-03	GO:0010556	regulation of macromolecule biosynthetic process
4.39	8.05e-03	GO:0010468	regulation of gene expression
4.31	9.15e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.28	9.60e-03	GO:0031326	regulation of cellular biosynthetic process
4.27	9.88e-03	GO:0051171	regulation of nitrogen compound metabolic process
4.23	1.05e-02	GO:0009889	regulation of biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
8.42	2.23e-02	GO:0044451	nucleoplasm part
13.45	2.99e-02	GO:0005667	transcription factor complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
11.22	1.13e-04	GO:0001071	nucleic acid binding transcription factor activity
11.22	1.13e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
7.81	4.86e-03	GO:0030528	transcription regulator activity
4.88	1.26e-02	GO:0003677	DNA binding
13.27	2.55e-02	GO:0008134	transcription factor binding