Motif ID: MAFB.p2

Z-value: 2.855

Transcription factors associated with MAFB.p2:

NameEntrezDescription
Mafb 16658 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Mafbchr2_-_160192799-0.251.5e-01Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr16_-_67621054 27.552 NM_001145977
NM_178721
Cadm2

cell adhesion molecule 2

chr14_-_40286236 12.702 NM_001190187
NM_001190188
NM_008734
Nrg3


neuregulin 3


chr18_-_43059156 12.347 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chrX_-_20498021 12.306 NM_001110780
NM_013680
Syn1

synapsin I

chr4_+_103291963 12.248


chr11_+_104092809 11.793 Mapt
microtubule-associated protein tau
chrX_+_66613505 11.349 NM_008032
Aff2
AF4/FMR2 family, member 2
chr19_-_59150001 11.133 4930506M07Rik
RIKEN cDNA 4930506M07 gene
chr8_-_87461251 10.749 NM_019945
Mast1
microtubule associated serine/threonine kinase 1
chr5_+_43625165 10.249 Cpeb2
cytoplasmic polyadenylation element binding protein 2
chr6_-_113841295 10.078 Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr5_+_81449776 9.811 Lphn3
latrophilin 3
chr3_+_45182311 9.168 NM_001098170
NM_001098171
NM_001098172
NM_011043
Pcdh10



protocadherin 10



chr10_+_101621491 8.543 NM_001162368
Mgat4c
4930402I19Rik
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
RIKEN cDNA 4930402I19 gene
chr4_+_103292164 8.448 Dab1
disabled homolog 1 (Drosophila)
chr2_-_25174498 8.402 Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr12_-_73509925 8.380 NM_153457
Rtn1
reticulon 1
chr5_-_108978950 8.218 NM_007756
Cplx1
complexin 1
chr17_-_24826873 8.108 NM_011522
Syngr3
synaptogyrin 3
chr16_+_38089536 7.348 Gsk3b
glycogen synthase kinase 3 beta
chr13_+_118391270 7.290 Hcn1
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr10_-_80945445 7.242 NM_176954
Celf5
CUGBP, Elav-like family member 5
chr5_-_21850490 7.142 NM_011261
Reln
reelin
chr1_-_127808723 7.109 Lypd1
Ly6/Plaur domain containing 1
chr2_-_156817751 7.098 NM_013865
NM_180956
Ndrg3

N-myc downstream regulated gene 3

chr2_-_60801248 7.074 NM_020296
Rbms1
RNA binding motif, single stranded interacting protein 1
chr11_+_104092789 6.922 Mapt
microtubule-associated protein tau
chr1_+_169528492 6.911 NM_009107
Rxrg
retinoid X receptor gamma
chr10_+_59568976 6.739 NM_052994
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr1_-_52290058 6.574 NM_001081081
NM_001113383
Gls

glutaminase

chr11_-_75609557 6.561 NM_007873
Doc2b
double C2, beta
chr9_-_97933599 6.089 Clstn2
calsyntenin 2
chr1_+_75502181 6.087 Obsl1
obscurin-like 1
chr10_+_39451923 6.083 NM_011264
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr8_-_87461220 6.033 Mast1
microtubule associated serine/threonine kinase 1
chr7_+_106415956 5.950 NM_001048167
NM_010837
Mtap6

microtubule-associated protein 6

chr14_-_40286109 5.836 Nrg3
neuregulin 3
chr2_-_25174662 5.831 NM_001177656
NM_001177657
NM_008169
Grin1


glutamate receptor, ionotropic, NMDA1 (zeta 1)


chr12_-_73509668 5.825 Rtn1
reticulon 1
chr11_+_104092749 5.671 NM_001038609
NM_010838
Mapt

microtubule-associated protein tau

chr14_-_13655592 5.553 NM_001042617
NM_012061
Cadps

Ca2+-dependent secretion activator

chr7_-_31230577 5.541 NM_007467
Aplp1
amyloid beta (A4) precursor-like protein 1
chr11_+_77744280 5.507 NM_021286
Sez6
seizure related gene 6
chr1_+_50984361 5.485 NM_019790
Tmeff2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr9_-_108092712 5.485 NM_007567
Bsn
bassoon
chr7_+_28438881 5.475 NM_028417
Ttc9b
tetratricopeptide repeat domain 9B
chr2_-_60800904 5.473 Rbms1
RNA binding motif, single stranded interacting protein 1
chr13_+_54472705 5.366 NM_009946
Cplx2
complexin 2
chr3_-_143868114 5.174 Lmo4
LIM domain only 4
chr16_-_20621287 5.142 NM_028420
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr17_-_24826812 5.132 Syngr3
synaptogyrin 3
chr2_+_37372112 5.127 NM_177383
Gpr21
G protein-coupled receptor 21
chr10_+_105907394 5.066 NM_177373
Ppfia2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chrX_-_67618235 5.041 NM_010498
Ids
iduronate 2-sulfatase
chr6_-_124867962 4.997 NM_026988
Ptms
parathymosin
chr2_+_118605431 4.987 NM_170593
Disp2
dispatched homolog 2 (Drosophila)
chr18_+_59334993 4.889 NM_001081328
Chsy3
chondroitin sulfate synthase 3
chr10_-_42894259 4.862 NM_175407
Sobp
sine oculis-binding protein homolog (Drosophila)
chr13_+_55050729 4.856 NM_153131
Unc5a
unc-5 homolog A (C. elegans)
chrX_+_7496899 4.835 NM_013892
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr2_+_134611879 4.800 NM_001145830
NM_019677
Plcb1

phospholipase C, beta 1

chr14_-_68742863 4.783 Nefm
neurofilament, medium polypeptide
chr18_-_43552694 4.741 NM_009468
Dpysl3
dihydropyrimidinase-like 3
chr16_-_52453104 4.738 NM_009655
Alcam
activated leukocyte cell adhesion molecule
chr1_-_137481880 4.728 Nav1
neuron navigator 1
chr4_+_43419445 4.689 NM_199057
Rusc2
RUN and SH3 domain containing 2
chr7_+_53651811 4.635 NM_008421
NM_001112739
Kcnc1

potassium voltage gated channel, Shaw-related subfamily, member 1

chr4_-_133054355 4.622 NM_001081156
Trnp1
TMF1-regulated nuclear protein 1
chr9_-_29770699 4.599 NM_172290
Ntm
neurotrimin
chr8_-_67171805 4.592 NM_013494
Cpe
carboxypeptidase E
chr11_+_68902025 4.587 NM_009497
Vamp2
vesicle-associated membrane protein 2
chrX_-_35605544 4.533 Fam70a
family with sequence similarity 70, member A
chr5_+_43625194 4.411 Cpeb2
cytoplasmic polyadenylation element binding protein 2
chr4_-_154719714 4.378 Prkcz
protein kinase C, zeta
chr4_-_120689813 4.369 NM_133716
Smap2
stromal membrane-associated GTPase-activating protein 2
chr6_-_37249957 4.340 NM_001081206
Dgki
diacylglycerol kinase, iota
chr10_+_106708886 4.316 NM_001033223
NM_001039354
Lin7a

lin-7 homolog A (C. elegans)

chr1_-_137481914 4.296 NM_173437
Nav1
neuron navigator 1
chr4_-_151235758 4.291 Camta1
calmodulin binding transcription activator 1
chr5_-_113006173 4.256 NM_019982
Sez6l
seizure related 6 homolog like
chr2_-_33226946 4.256 Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr7_-_31230564 4.236 Aplp1
amyloid beta (A4) precursor-like protein 1
chr12_+_78340039 4.200 Fut8
fucosyltransferase 8
chr12_-_32746061 4.195 NM_011158
Prkar2b
protein kinase, cAMP dependent regulatory, type II beta
chr8_-_89996474 4.157 NM_019626
Cbln1
cerebellin 1 precursor protein
chr3_-_97571903 4.097 NM_178080
Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)
chr16_+_38089607 4.096 Gsk3b
glycogen synthase kinase 3 beta
chr16_-_23890909 4.073 NM_009215
Sst
somatostatin
chr9_+_110147867 4.065 Cspg5
chondroitin sulfate proteoglycan 5
chr1_+_62749850 4.052 NM_001077403
NM_001077404
NM_001077405
NM_001077406
NM_001077407
NM_010939
Nrp2





neuropilin 2





chrX_+_7215705 4.050 NM_009305
Syp
synaptophysin
chr12_-_42212538 4.027 Lrrn3
leucine rich repeat protein 3, neuronal
chr5_+_110973321 3.955 NM_198306
Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr7_-_117758395 3.905 Sbf2
SET binding factor 2
chr7_-_117758413 3.883 NM_177324
Sbf2
SET binding factor 2
chr6_+_105627738 3.875 NM_001109749
NM_173004
Cntn4

contactin 4

chr6_-_58857000 3.850 NM_021432
Nap1l5
nucleosome assembly protein 1-like 5
chrX_+_71542444 3.830 Atp6ap1
ATPase, H+ transporting, lysosomal accessory protein 1
chr9_-_86775154 3.825 NM_013669
Snap91
synaptosomal-associated protein 91
chr1_-_160286359 3.802 NM_207583
Fam5b
family with sequence similarity 5, member B
chr2_-_102241053 3.796 NM_020267
Trim44
tripartite motif-containing 44
chr5_-_65884169 3.735 1110003E01Rik
RIKEN cDNA 1110003E01 gene
chr14_-_13655558 3.720 Cadps
Ca2+-dependent secretion activator
chr14_-_75347637 3.715 NM_001033439
Lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr2_-_150730457 3.698 NM_024465
Abhd12
abhydrolase domain containing 12
chr14_+_77556622 3.666 NM_172813
Enox1
ecto-NOX disulfide-thiol exchanger 1
chr18_+_38456280 3.603 NM_001164622
NM_020012
Rnf14

ring finger protein 14

chr6_-_77929660 3.558 NM_001109764
NM_009819
NM_145732
Ctnna2


catenin (cadherin associated protein), alpha 2


chr9_-_123169866 3.549 NM_001002267
Tmem158
transmembrane protein 158
chr13_-_104899571 3.547 NM_029447
Nln
neurolysin (metallopeptidase M3 family)
chr19_-_7557678 3.535 Rtn3
reticulon 3
chr10_-_126971614 3.482 NM_183297
Nxph4
neurexophilin 4
chr1_-_133421746 3.430 Srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr4_-_41516463 3.408 NM_001159583
NM_027993
2310028H24Rik

RIKEN cDNA 2310028H24 gene

chr1_-_33964439 3.395 NM_177235
Bend6
BEN domain containing 6
chr13_+_58909236 3.389 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr6_-_77929575 3.377 Ctnna2
catenin (cadherin associated protein), alpha 2
chr10_+_59569052 3.374 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr4_+_151712914 3.366 Chd5
chromodomain helicase DNA binding protein 5
chr15_+_82086506 3.354 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr14_+_77556569 3.311 Enox1
ecto-NOX disulfide-thiol exchanger 1
chr2_-_33226980 3.263 NM_175211
Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr5_+_30890386 3.260 NM_010608
Kcnk3
potassium channel, subfamily K, member 3
chr6_-_77929543 3.250 Ctnna2
catenin (cadherin associated protein), alpha 2
chr15_-_37389073 3.249 NM_001170867
NM_001170868
Ncald

neurocalcin delta

chr4_+_102432943 3.248 NM_144906
Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr7_-_31230463 3.212 Aplp1
amyloid beta (A4) precursor-like protein 1
chr6_-_113841356 3.165 NM_001036684
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr12_+_80231774 3.120 NM_009705
Arg2
arginase type II
chr13_-_54712629 3.115 NM_028870
Cltb
clathrin, light polypeptide (Lcb)
chr2_-_151458299 3.103 Snph
syntaphilin
chr1_-_177422630 3.087 NM_001199003
NM_011880
Rgs7

regulator of G protein signaling 7

chr11_-_120645428 3.051 NM_009053
Rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr15_-_25343483 3.038 NM_027395
Basp1
brain abundant, membrane attached signal protein 1
chr5_-_133019090 3.022


chr15_+_30102306 3.013 NM_008729
Ctnnd2
catenin (cadherin associated protein), delta 2
chr2_-_102241003 3.006 Trim44
tripartite motif-containing 44
chr4_-_129118034 2.998 NM_153541
Zbtb8b
zinc finger and BTB domain containing 8b
chr10_+_28867072 2.995 6330407J23Rik
RIKEN cDNA 6330407J23 gene
chr8_+_96335202 2.959 Gnao1
guanine nucleotide binding protein, alpha O
chr4_+_107474842 2.925 NM_001080926
Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr7_+_26091105 2.908 NM_183311
Tmem145
transmembrane protein 145
chr6_+_110595574 2.897 Grm7
glutamate receptor, metabotropic 7
chr18_+_38456315 2.893 Rnf14
ring finger protein 14
chrX_-_101396356 2.886 NM_001077354
C77370
expressed sequence C77370
chr1_-_127332217 2.884 Actr3
ARP3 actin-related protein 3 homolog (yeast)
chr7_+_53040723 2.869 Lmtk3
lemur tyrosine kinase 3
chr12_+_78339802 2.865 Fut8
fucosyltransferase 8
chr14_-_21613162 2.864 NM_001039138
NM_001039139
NM_178597
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr17_-_63849928 2.830 NM_015794
Fbxl17
F-box and leucine-rich repeat protein 17
chr18_-_62071494 2.823 NM_001164491
Ablim3
actin binding LIM protein family, member 3
chr2_+_155102040 2.794 NM_025735
Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr10_-_121484248 2.775 NM_001081037
Srgap1
SLIT-ROBO Rho GTPase activating protein 1
chr11_+_104092793 2.771 Mapt
microtubule-associated protein tau
chr9_+_68501551 2.761 NM_013646
Rora
RAR-related orphan receptor alpha
chr13_+_54472833 2.758 Cplx2
complexin 2
chr18_-_16967100 2.755 Cdh2
cadherin 2
chr12_+_45429857 2.751 NM_001146031
NM_176930
Nrcam

neuron-glia-CAM-related cell adhesion molecule

chr7_+_97535490 2.725 NM_001040087
NM_001040088
Sytl2

synaptotagmin-like 2

chr9_+_45238375 2.712 NM_001081270
Dscaml1
Down syndrome cell adhesion molecule-like 1
chr16_-_46496886 2.710 NM_021495
NM_021496
NM_021497
Pvrl3


poliovirus receptor-related 3


chr3_-_143865162 2.710 NM_001161770
NM_001161769
Lmo4

LIM domain only 4

chr18_-_23200150 2.708 NM_199024
Nol4
nucleolar protein 4
chr3_-_57651409 2.705 Pfn2
profilin 2
chr10_-_80945379 2.704 Celf5
CUGBP, Elav-like family member 5
chr3_+_13471643 2.704 NM_001163328
NM_178631
Ralyl

RALY RNA binding protein-like

chr11_+_16157685 2.700 NM_145967
Vstm2a
V-set and transmembrane domain containing 2A
chr11_+_79404517 2.695 Rab11fip4
RAB11 family interacting protein 4 (class II)
chr17_-_66426361 2.691 NM_001025572
Ankrd12
ankyrin repeat domain 12
chr18_+_45719101 2.689 Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chrX_-_152057864 2.688 NM_001093750
Ptchd1
patched domain containing 1
chr14_-_55531726 2.680 NM_021551
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr2_+_174153230 2.680 Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr3_-_88964115 2.642 Hcn3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr6_+_115084919 2.634 NM_001111015
NM_013681
Syn2

synapsin II

chr2_+_134611931 2.624 Plcb1
phospholipase C, beta 1
chr7_+_120351012 2.621 Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr1_+_66221851 2.618 NM_001039934
NM_008632
Mtap2

microtubule-associated protein 2

chr11_-_102308966 2.599 NM_199200
Fam171a2
family with sequence similarity 171, member A2
chr2_+_21289168 2.588 NM_001004761
Gpr158
G protein-coupled receptor 158
chr9_-_40153864 2.566 Gramd1b
GRAM domain containing 1B
chr8_+_120807621 2.558 NM_019707
Cdh13
cadherin 13
chr11_-_79068138 2.552 NM_019653
Wsb1
WD repeat and SOCS box-containing 1
chr19_+_36629128 2.550 NM_001163471
NM_172637
Hectd2

HECT domain containing 2

chr5_-_69732792 2.539 Kctd8
potassium channel tetramerisation domain containing 8
chr4_+_102432879 2.536 Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr8_+_65430028 2.530 NM_023689
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr3_-_89049088 2.510 NM_001039466
Trim46
tripartite motif-containing 46
chr15_+_54402914 2.496 NM_178920
Mal2
mal, T-cell differentiation protein 2
chr6_-_32538191 2.495 NM_175750
Plxna4
plexin A4
chr8_+_73278577 2.489 NM_001166399
NM_009001
Rab3a

RAB3A, member RAS oncogene family

chr6_-_77929685 2.483 Ctnna2
catenin (cadherin associated protein), alpha 2
chr7_+_108599819 2.483 Pde2a
phosphodiesterase 2A, cGMP-stimulated
chr18_-_25912171 2.476 Celf4
CUGBP, Elav-like family member 4
chr1_+_160292665 2.472 Astn1
astrotactin 1
chr16_-_60605072 2.466 Epha6
Eph receptor A6
chr2_+_157385835 2.463 NM_010923
NM_180960
Nnat

neuronatin

chr3_-_131006068 2.458 NM_027816
Cyp2u1
cytochrome P450, family 2, subfamily u, polypeptide 1
chr12_+_45429966 2.454 Nrcam
neuron-glia-CAM-related cell adhesion molecule
chr10_+_122115755 2.449 NM_001110218
NM_176919
Ppm1h

protein phosphatase 1H (PP2C domain containing)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
2.82 2.80e-14 GO:0007399 nervous system development
3.23 8.49e-13 GO:0048699 generation of neurons
3.07 4.71e-12 GO:0022008 neurogenesis
1.87 1.17e-11 GO:0051179 localization
5.15 6.92e-10 GO:0007409 axonogenesis
4.85 1.28e-09 GO:0048667 cell morphogenesis involved in neuron differentiation
3.72 2.73e-09 GO:0048666 neuron development
4.10 4.83e-09 GO:0031175 neuron projection development
1.85 8.86e-09 GO:0051234 establishment of localization
3.13 1.26e-08 GO:0040011 locomotion
1.85 1.39e-08 GO:0006810 transport
3.37 1.65e-08 GO:0030030 cell projection organization
4.49 2.25e-08 GO:0048812 neuron projection morphogenesis
2.68 2.91e-08 GO:0051649 establishment of localization in cell
2.49 5.26e-08 GO:0051641 cellular localization
3.18 6.23e-08 GO:0030182 neuron differentiation
11.38 7.68e-08 GO:0007269 neurotransmitter secretion
3.95 1.17e-07 GO:0000904 cell morphogenesis involved in differentiation
4.17 1.36e-07 GO:0045664 regulation of neuron differentiation
3.84 4.87e-07 GO:0048858 cell projection morphogenesis
3.31 5.34e-07 GO:0000902 cell morphogenesis
3.76 7.85e-07 GO:0032990 cell part morphogenesis
4.03 1.29e-06 GO:0007268 synaptic transmission
7.60 1.31e-06 GO:0001505 regulation of neurotransmitter levels
2.34 1.59e-06 GO:0032879 regulation of localization
2.61 2.15e-06 GO:0051049 regulation of transport
4.47 3.09e-06 GO:0031344 regulation of cell projection organization
6.01 4.51e-06 GO:0003001 generation of a signal involved in cell-cell signaling
6.01 4.51e-06 GO:0023061 signal release
4.76 5.10e-06 GO:0010975 regulation of neuron projection development
3.04 5.24e-06 GO:0032989 cellular component morphogenesis
1.77 6.06e-06 GO:0048731 system development
3.31 9.30e-06 GO:0051960 regulation of nervous system development
2.73 1.01e-05 GO:0016192 vesicle-mediated transport
3.46 1.07e-05 GO:0050767 regulation of neurogenesis
3.43 1.31e-05 GO:0019226 transmission of nerve impulse
3.43 1.31e-05 GO:0035637 multicellular organismal signaling
6.35 1.77e-05 GO:0006836 neurotransmitter transport
2.04 2.17e-05 GO:0009653 anatomical structure morphogenesis
1.79 2.62e-05 GO:0071842 cellular component organization at cellular level
3.09 2.73e-05 GO:0007267 cell-cell signaling
7.25 3.16e-05 GO:0021543 pallium development
1.65 3.56e-05 GO:0016043 cellular component organization
1.68 3.70e-05 GO:0048856 anatomical structure development
8.64 5.72e-05 GO:0021987 cerebral cortex development
2.47 1.15e-04 GO:0006468 protein phosphorylation
2.32 1.26e-04 GO:0051128 regulation of cellular component organization
2.97 1.81e-04 GO:0060284 regulation of cell development
4.97 2.05e-04 GO:0007411 axon guidance
1.59 2.10e-04 GO:0071840 cellular component organization or biogenesis
5.20 2.72e-04 GO:0021537 telencephalon development
1.70 3.01e-04 GO:0071841 cellular component organization or biogenesis at cellular level
2.30 4.17e-04 GO:0045595 regulation of cell differentiation
2.96 5.05e-04 GO:0016477 cell migration
2.43 5.13e-04 GO:0007154 cell communication
1.57 5.30e-04 GO:0007275 multicellular organismal development
1.72 6.40e-04 GO:0048869 cellular developmental process
2.21 6.41e-04 GO:0048468 cell development
1.73 6.99e-04 GO:0030154 cell differentiation
2.47 7.04e-04 GO:0046907 intracellular transport
3.58 7.31e-04 GO:0032940 secretion by cell
3.03 8.42e-04 GO:0007420 brain development
5.78 1.47e-03 GO:0030902 hindbrain development
2.74 1.51e-03 GO:0048870 cell motility
2.74 1.51e-03 GO:0051674 localization of cell
2.19 1.57e-03 GO:0016310 phosphorylation
6.32 1.65e-03 GO:0017157 regulation of exocytosis
11.72 1.93e-03 GO:0016079 synaptic vesicle exocytosis
1.83 2.17e-03 GO:0051239 regulation of multicellular organismal process
7.88 2.33e-03 GO:0016358 dendrite development
1.51 2.38e-03 GO:0032502 developmental process
6.05 2.60e-03 GO:0016050 vesicle organization
2.63 3.43e-03 GO:0006928 cellular component movement
2.96 3.49e-03 GO:0046903 secretion
2.63 3.59e-03 GO:0007417 central nervous system development
1.98 5.21e-03 GO:0050793 regulation of developmental process
2.48 5.28e-03 GO:0030001 metal ion transport
1.99 5.59e-03 GO:0006796 phosphate metabolic process
1.24 5.70e-03 GO:0065007 biological regulation
1.99 5.93e-03 GO:0006793 phosphorus metabolic process
7.07 6.02e-03 GO:0022037 metencephalon development
2.73 6.08e-03 GO:0007610 behavior
17.50 6.95e-03 GO:0021799 cerebral cortex radially oriented cell migration
3.76 8.93e-03 GO:0060627 regulation of vesicle-mediated transport
3.25 1.04e-02 GO:0031644 regulation of neurological system process
5.83 1.08e-02 GO:0018209 peptidyl-serine modification
3.88 1.19e-02 GO:0006813 potassium ion transport
3.35 1.21e-02 GO:0051969 regulation of transmission of nerve impulse
5.66 1.42e-02 GO:0007156 homophilic cell adhesion
7.33 1.57e-02 GO:0048489 synaptic vesicle transport
4.24 1.79e-02 GO:0006887 exocytosis
2.56 1.88e-02 GO:0044057 regulation of system process
2.26 1.89e-02 GO:0006812 cation transport
1.54 1.89e-02 GO:0048522 positive regulation of cellular process
4.93 2.02e-02 GO:0050770 regulation of axonogenesis
3.21 2.17e-02 GO:0030900 forebrain development
22.00 2.19e-02 GO:0021801 cerebral cortex radial glia guided migration
10.50 2.30e-02 GO:0021795 cerebral cortex cell migration
4.44 2.41e-02 GO:0031346 positive regulation of cell projection organization
2.50 2.91e-02 GO:0009719 response to endogenous stimulus
7.93 3.30e-02 GO:0021766 hippocampus development
1.87 3.46e-02 GO:0035556 intracellular signal transduction
1.49 3.48e-02 GO:0048518 positive regulation of biological process
3.72 3.80e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
3.72 3.80e-02 GO:0022604 regulation of cell morphogenesis
9.63 3.98e-02 GO:0010970 microtubule-based transport
9.63 3.98e-02 GO:0030705 cytoskeleton-dependent intracellular transport

Gene overrepresentation in compartment category:

enrichment p-value GO term description
5.01 1.38e-23 GO:0045202 synapse
4.37 9.24e-21 GO:0043005 neuron projection
5.09 1.49e-16 GO:0044456 synapse part
2.75 3.67e-13 GO:0042995 cell projection
1.78 1.61e-12 GO:0071944 cell periphery
1.77 1.30e-11 GO:0005886 plasma membrane
4.89 1.38e-11 GO:0030424 axon
3.45 1.30e-10 GO:0016023 cytoplasmic membrane-bounded vesicle
6.33 1.44e-10 GO:0030136 clathrin-coated vesicle
5.80 3.60e-10 GO:0030135 coated vesicle
3.27 8.54e-10 GO:0031988 membrane-bounded vesicle
10.70 1.25e-09 GO:0030665 clathrin coated vesicle membrane
2.89 1.85e-09 GO:0031410 cytoplasmic vesicle
8.80 6.32e-09 GO:0030662 coated vesicle membrane
2.72 1.80e-08 GO:0031982 vesicle
3.76 2.01e-08 GO:0044297 cell body
4.05 2.37e-08 GO:0030425 dendrite
3.83 2.49e-08 GO:0043025 neuronal cell body
5.40 3.45e-08 GO:0030659 cytoplasmic vesicle membrane
5.23 6.40e-08 GO:0044433 cytoplasmic vesicle part
6.61 1.81e-07 GO:0008021 synaptic vesicle
4.90 2.30e-07 GO:0012506 vesicle membrane
5.54 4.01e-07 GO:0033267 axon part
3.19 7.75e-07 GO:0044463 cell projection part
1.87 3.75e-06 GO:0044459 plasma membrane part
1.14 4.05e-06 GO:0005623 cell
1.14 4.05e-06 GO:0044464 cell part
6.66 5.39e-06 GO:0030426 growth cone
1.30 8.60e-06 GO:0016020 membrane
6.42 8.74e-06 GO:0030427 site of polarized growth
6.42 8.74e-06 GO:0044306 neuron projection terminus
1.30 9.71e-06 GO:0005737 cytoplasm
2.37 1.17e-05 GO:0012505 endomembrane system
1.21 5.60e-05 GO:0005622 intracellular
2.46 6.58e-05 GO:0030054 cell junction
2.16 7.61e-05 GO:0005626 insoluble fraction
10.62 1.43e-04 GO:0030672 synaptic vesicle membrane
2.10 1.67e-04 GO:0005794 Golgi apparatus
1.96 1.97e-04 GO:0000267 cell fraction
5.92 2.08e-04 GO:0043679 axon terminus
2.13 2.77e-04 GO:0005624 membrane fraction
1.30 4.33e-04 GO:0044425 membrane part
7.70 5.30e-04 GO:0005905 coated pit
3.07 5.93e-04 GO:0044431 Golgi apparatus part
8.80 6.83e-04 GO:0030666 endocytic vesicle membrane
3.83 1.31e-03 GO:0045211 postsynaptic membrane
1.18 2.34e-03 GO:0044424 intracellular part
2.84 3.27e-03 GO:0048471 perinuclear region of cytoplasm
1.50 3.28e-03 GO:0043234 protein complex
13.75 5.26e-03 GO:0048786 presynaptic active zone
6.70 5.89e-03 GO:0043195 terminal button
1.31 6.34e-03 GO:0044444 cytoplasmic part
1.79 6.58e-03 GO:0031090 organelle membrane
19.25 7.98e-03 GO:0061200 clathrin sculpted gamma-aminobutyric acid transport vesicle
19.25 7.98e-03 GO:0061202 clathrin sculpted gamma-aminobutyric acid transport vesicle membrane
5.59 8.21e-03 GO:0030117 membrane coat
5.59 8.21e-03 GO:0048475 coated membrane
17.11 1.41e-02 GO:0030132 clathrin coat of coated pit
17.11 1.41e-02 GO:0060198 clathrin sculpted vesicle
3.68 1.52e-02 GO:0019717 synaptosome
4.64 1.56e-02 GO:0014069 postsynaptic density
6.91 1.57e-02 GO:0030118 clathrin coat
3.43 1.71e-02 GO:0000139 Golgi membrane
15.40 2.30e-02 GO:0000159 protein phosphatase type 2A complex
4.75 3.05e-02 GO:0019897 extrinsic to plasma membrane
9.63 3.58e-02 GO:0031201 SNARE complex
23.10 4.62e-02 GO:0030122 AP-2 adaptor complex

Gene overrepresentation in function category:

enrichment p-value GO term description
1.62 2.95e-14 GO:0005515 protein binding
1.29 5.47e-10 GO:0005488 binding
3.33 1.03e-04 GO:0022836 gated channel activity
4.70 2.45e-04 GO:0005516 calmodulin binding
1.64 9.13e-04 GO:0000166 nucleotide binding
2.32 2.62e-03 GO:0004672 protein kinase activity
2.04 2.83e-03 GO:0030234 enzyme regulator activity
3.07 3.33e-03 GO:0005261 cation channel activity
1.66 3.44e-03 GO:0017076 purine nucleotide binding
2.64 3.87e-03 GO:0005216 ion channel activity
2.01 3.93e-03 GO:0019899 enzyme binding
2.32 4.63e-03 GO:0019904 protein domain specific binding
2.04 4.72e-03 GO:0016301 kinase activity
1.65 5.49e-03 GO:0032555 purine ribonucleotide binding
2.58 5.60e-03 GO:0022838 substrate-specific channel activity
1.64 5.60e-03 GO:0032553 ribonucleotide binding
3.42 6.75e-03 GO:0005244 voltage-gated ion channel activity
3.42 6.75e-03 GO:0022832 voltage-gated channel activity
4.04 7.13e-03 GO:0005267 potassium channel activity
2.49 7.36e-03 GO:0004674 protein serine/threonine kinase activity
2.11 7.65e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.50 9.50e-03 GO:0015267 channel activity
2.50 9.92e-03 GO:0022803 passive transmembrane transporter activity
3.82 1.28e-02 GO:0022843 voltage-gated cation channel activity
2.07 1.42e-02 GO:0015075 ion transmembrane transporter activity
4.02 1.55e-02 GO:0017124 SH3 domain binding
1.88 1.71e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
2.23 1.91e-02 GO:0005509 calcium ion binding
2.25 2.16e-02 GO:0008324 cation transmembrane transporter activity
2.20 2.27e-02 GO:0008092 cytoskeletal protein binding
1.59 2.96e-02 GO:0035639 purine ribonucleoside triphosphate binding
4.28 3.90e-02 GO:0005249 voltage-gated potassium channel activity