Motif ID: MYFfamily.p2

Z-value: 3.276

Transcription factors associated with MYFfamily.p2:

NameEntrezDescription
Myf5 17877 myogenic factor 5
Myf6 17878 myogenic factor 6
Myod1 17927 myogenic differentiation 1
Myog 17928 myogenin

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Myod1chr7_+_536318430.344.0e-02Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr16_-_67621054 33.404 NM_001145977
NM_178721
Cadm2

cell adhesion molecule 2

chr4_-_66065499 30.625 NM_019514
NM_207109
Astn2

astrotactin 2

chr6_-_126690651 23.631 NM_013568
Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chrX_-_119510890 23.133 NM_138742
Nap1l3
nucleosome assembly protein 1-like 3
chr8_+_96676506 21.526 NM_013603
Mt3
metallothionein 3
chr5_+_43625165 20.726 Cpeb2
cytoplasmic polyadenylation element binding protein 2
chrX_+_70748418 19.864 NM_177236
Atp2b3
ATPase, Ca++ transporting, plasma membrane 3
chr18_+_45719101 16.357 Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr9_+_27598853 16.357 NM_177906
Opcml
opioid binding protein/cell adhesion molecule-like
chr17_+_35373506 15.515 NM_023179
Atp6v1g2
ATPase, H+ transporting, lysosomal V1 subunit G2
chr16_-_28753276 15.104 NM_010199
Fgf12
fibroblast growth factor 12
chr6_-_23789259 14.384 NM_153163
Cadps2
Ca2+-dependent activator protein for secretion 2
chr8_-_87461251 14.108 NM_019945
Mast1
microtubule associated serine/threonine kinase 1
chr2_-_156817751 13.950 NM_013865
NM_180956
Ndrg3

N-myc downstream regulated gene 3

chr2_+_180332926 13.350 NM_009936
Col9a3
collagen, type IX, alpha 3
chr7_+_129432585 13.280 NM_008855
Prkcb
protein kinase C, beta
chr4_+_103291963 13.150


chr2_+_155601077 13.095 NM_010808
Mmp24
matrix metallopeptidase 24
chr4_+_104829963 12.873 Ppap2b
phosphatidic acid phosphatase type 2B
chr8_+_128519001 12.851 NM_008430
Kcnk1
potassium channel, subfamily K, member 1
chr16_+_91270009 12.770 NM_016968
Olig1
oligodendrocyte transcription factor 1
chr18_+_37975071 12.659 Pcdhgc4
protocadherin gamma subfamily C, 4
chr9_+_45178267 12.396 NM_022004
Fxyd6
FXYD domain-containing ion transport regulator 6
chr1_-_125942073 12.258 NM_199021
Dpp10
dipeptidylpeptidase 10
chrX_-_131745187 12.024 NM_025355
Tceal6
transcription elongation factor A (SII)-like 6
chr4_+_104829951 11.808 NM_080555
Ppap2b
phosphatidic acid phosphatase type 2B
chr7_-_31836457 11.774 NM_022007
Fxyd7
FXYD domain-containing ion transport regulator 7
chr12_-_73509668 11.513 Rtn1
reticulon 1
chr4_+_130348406 11.149 NM_011520
Sdc3
syndecan 3
chr7_+_26091105 11.042 NM_183311
Tmem145
transmembrane protein 145
chr5_-_77837037 11.016 NM_001159518
NM_008048
Igfbp7

insulin-like growth factor binding protein 7

chr13_+_58909236 10.725 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr13_+_58909168 10.641 NM_001025074
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr1_+_81073778 10.542 NM_172849
9430031J16Rik
RIKEN cDNA 9430031J16 gene
chr16_-_28753298 10.366 Fgf12
fibroblast growth factor 12
chr8_-_87461220 10.328 Mast1
microtubule associated serine/threonine kinase 1
chr8_-_89996474 10.273 NM_019626
Cbln1
cerebellin 1 precursor protein
chr8_+_128519295 10.221 Kcnk1
potassium channel, subfamily K, member 1
chr9_+_75473524 10.093 NM_027309
Lysmd2
LysM, putative peptidoglycan-binding, domain containing 2
chr8_-_108467294 9.821 NM_008490
Lcat
lecithin cholesterol acyltransferase
chr7_+_3303657 9.462 NM_011102
Prkcc
protein kinase C, gamma
chr11_+_119804400 9.381 NM_001037754
NM_001037755
NM_130862
Baiap2


brain-specific angiogenesis inhibitor 1-associated protein 2


chr2_+_61884596 9.085 NM_033552
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr14_-_40286236 9.075 NM_001190187
NM_001190188
NM_008734
Nrg3


neuregulin 3


chr4_-_25726753 8.999 Fut9
fucosyltransferase 9
chr1_-_84692352 8.953 Dner
delta/notch-like EGF-related receptor
chr18_+_45719464 8.847 Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr2_+_25118144 8.830 Tprn
taperin
chr14_+_34736806 8.828 Gdf10
growth differentiation factor 10
chr10_-_59079420 8.759 Ccdc109a
coiled-coil domain containing 109A
chr8_-_89996089 8.759 Cbln1
cerebellin 1 precursor protein
chr4_-_63707964 8.662 Tnc
tenascin C
chr7_-_25790888 8.597 NM_144921
Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr13_-_12199109 8.524 NM_023868
Ryr2
ryanodine receptor 2, cardiac
chr1_-_166387998 8.439 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr18_-_43058544 8.372 NM_027531
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr4_-_133054355 8.292 NM_001081156
Trnp1
TMF1-regulated nuclear protein 1
chr6_-_37249957 8.262 NM_001081206
Dgki
diacylglycerol kinase, iota
chr7_+_53651811 8.217 NM_008421
NM_001112739
Kcnc1

potassium voltage gated channel, Shaw-related subfamily, member 1

chr18_-_43059156 8.182 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr3_-_143865162 8.058 NM_001161770
NM_001161769
Lmo4

LIM domain only 4

chr3_+_89324085 7.944 NM_080466
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr1_-_175297778 7.739 NM_053199
Cadm3
cell adhesion molecule 3
chr11_+_3414884 7.567 Selm
selenoprotein M
chr13_+_64263131 7.504 NM_019986
Habp4
hyaluronic acid binding protein 4
chr7_-_134164627 7.430 NM_001102563
Prrt2
proline-rich transmembrane protein 2
chr10_+_59568976 7.299 NM_052994
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr18_-_14131046 7.291 NM_145492
Zfp521
zinc finger protein 521
chr5_+_89315839 7.186 Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr2_+_21289168 7.133 NM_001004761
Gpr158
G protein-coupled receptor 158
chr5_+_43625194 7.044 Cpeb2
cytoplasmic polyadenylation element binding protein 2
chr12_+_117724182 7.003 NM_011215
Ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr11_-_4847968 6.974 NM_010904
Nefh
neurofilament, heavy polypeptide
chr7_+_80885223 6.934 Fam174b
family with sequence similarity 174, member B
chr10_-_42894259 6.925 NM_175407
Sobp
sine oculis-binding protein homolog (Drosophila)
chr9_+_57787915 6.851 NM_011352
Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr2_-_122436933 6.811 NM_025961
Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr5_+_33361479 6.722 Ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr9_+_58430210 6.716 Nptn
neuroplastin
chr14_-_16271386 6.686 NM_146052
Lrrc3b
leucine rich repeat containing 3B
chr14_-_103381744 6.668 NM_177715
Kctd12
potassium channel tetramerisation domain containing 12
chr18_+_35000283 6.630 NM_144865
Reep2
receptor accessory protein 2
chr18_+_59334993 6.590 NM_001081328
Chsy3
chondroitin sulfate synthase 3
chr8_-_73011217 6.589 NM_182991
Tmem59l
transmembrane protein 59-like
chr1_+_11404185 6.588 NM_001160369
NM_001160370
NM_001160371
NM_177173
A830018L16Rik



RIKEN cDNA A830018L16 gene



chr6_-_113991945 6.546 NM_009723
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr5_-_38550627 6.539 NM_010942
Nsg1
neuron specific gene family member 1
chr6_+_113232319 6.521 Cpne9
copine family member IX
chr2_-_90420626 6.496 NM_008982
Ptprj
protein tyrosine phosphatase, receptor type, J
chr18_+_66033139 6.479 NM_175012
Grp
gastrin releasing peptide
chr11_-_5965626 6.459 Camk2b
calcium/calmodulin-dependent protein kinase II, beta
chr3_-_143868114 6.432 Lmo4
LIM domain only 4
chr14_+_34736772 6.416 NM_145741
Gdf10
growth differentiation factor 10
chr7_+_127986324 6.354 NM_007908
Eef2k
eukaryotic elongation factor-2 kinase
chrX_-_71126088 6.267 NM_008478
L1cam
L1 cell adhesion molecule
chr7_+_134094045 6.243 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr2_+_16277963 6.063 Plxdc2
plexin domain containing 2
chr15_-_37389073 6.046 NM_001170867
NM_001170868
Ncald

neurocalcin delta

chr10_+_39451923 6.042 NM_011264
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr6_-_23789048 5.948 Cadps2
Ca2+-dependent activator protein for secretion 2
chr2_-_25174498 5.938 Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr6_+_125165597 5.933 NM_001080557
NM_009496
Vamp1

vesicle-associated membrane protein 1

chr12_+_78339999 5.872 NM_016893
Fut8
fucosyltransferase 8
chr6_-_82889694 5.870 NM_001113481
NM_011350
Sema4f

sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain

chr12_-_71448300 5.841 Trim9
tripartite motif-containing 9
chr10_-_41996462 5.801 NM_019740
Foxo3
forkhead box O3
chr2_-_60800904 5.741 Rbms1
RNA binding motif, single stranded interacting protein 1
chr7_-_31912022 5.678 Scn1b
sodium channel, voltage-gated, type I, beta
chr14_-_55531726 5.639 NM_021551
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr7_+_129432810 5.635 Prkcb
protein kinase C, beta
chr10_+_75398588 5.611 Chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr10_+_81038028 5.599 NM_019725
Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr19_-_17912073 5.590 NM_001163144
NM_001190483
Pcsk5

proprotein convertase subtilisin/kexin type 5

chr15_-_58913543 5.586 NM_001146180
NM_144800
Mtss1

metastasis suppressor 1

chr15_-_63891810 5.567 NM_144846
Fam49b
family with sequence similarity 49, member B
chr17_-_27650285 5.484 Grm4
glutamate receptor, metabotropic 4
chr2_+_118605431 5.468 NM_170593
Disp2
dispatched homolog 2 (Drosophila)
chr9_+_69137694 5.466 Rora
RAR-related orphan receptor alpha
chr17_+_88840048 5.402 NM_180974
Foxn2
forkhead box N2
chr10_+_98377759 5.379 NM_026482
Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr6_+_66846377 5.313 NM_001177556
NM_001177557
NM_001177559
NM_001177560
NM_025278
Gng12




guanine nucleotide binding protein (G protein), gamma 12




chr5_-_35448316 5.309 NM_013587
Lrpap1
low density lipoprotein receptor-related protein associated protein 1
chrX_-_19868889 5.306 NM_177353
Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chrX_-_71070284 5.274 NM_001029868
Pdzd4
PDZ domain containing 4
chr8_-_17535279 5.261 NM_053171
Csmd1
CUB and Sushi multiple domains 1
chr15_+_12047769 5.261 Zfr
zinc finger RNA binding protein
chr2_-_25174662 5.245 NM_001177656
NM_001177657
NM_008169
Grin1


glutamate receptor, ionotropic, NMDA1 (zeta 1)


chr2_+_107130745 5.188 NM_021275
Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr13_+_94541584 5.124 NM_009712
Arsb
arylsulfatase B
chr9_+_110147867 5.079 Cspg5
chondroitin sulfate proteoglycan 5
chr18_+_36508277 5.077 NM_001081365
0610010O12Rik
RIKEN cDNA 0610010O12 gene
chr16_-_20621287 5.036 NM_028420
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr14_+_56109905 5.009 NM_001024645
Lrrc16b
leucine rich repeat containing 16B
chr2_-_162486792 5.001 Ptprt
protein tyrosine phosphatase, receptor type, T
chr11_+_16652205 5.000 NM_007912
NM_207655
Egfr

epidermal growth factor receptor

chr9_-_58884114 4.889 NM_001042752
NM_008684
Neo1

neogenin

chr16_+_94791713 4.888 NM_007890
Dyrk1a
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
chr16_+_6349108 4.781 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr8_-_87297283 4.777 Nfix
nuclear factor I/X
chr18_+_67247984 4.755 NM_177137
Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr15_-_74583382 4.680 NM_011838
Lynx1
Ly6/neurotoxin 1
chr4_+_126698539 4.653 NM_023603
Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr9_+_27598531 4.621 Opcml
opioid binding protein/cell adhesion molecule-like
chr1_-_166388431 4.607 NM_009721
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr2_+_83652779 4.600 Fam171b
family with sequence similarity 171, member B
chr15_+_81767188 4.577 NM_145473
Csdc2
cold shock domain containing C2, RNA binding
chr9_+_45178485 4.564 Fxyd6
FXYD domain-containing ion transport regulator 6
chrX_+_133200982 4.554 Tceal3
transcription elongation factor A (SII)-like 3
chr3_-_89126782 4.554 NM_010108
Efna3
ephrin A3
chr12_+_91050912 4.438 Nrxn3
neurexin III
chr7_-_17509228 4.427 NM_007590
Calm3
calmodulin 3
chr5_+_115392192 4.425 NM_028211
2210016L21Rik
RIKEN cDNA 2210016L21 gene
chr19_+_5741862 4.417 Ltbp3
latent transforming growth factor beta binding protein 3
chr10_+_40069255 4.397 Cdk19
cyclin-dependent kinase 19
chr11_+_105829223 4.378 NM_207624
Ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr13_+_81850415 4.371 NM_028372
Mblac2
metallo-beta-lactamase domain containing 2
chr3_-_158224306 4.371 Lrrc7
leucine rich repeat containing 7
chr11_+_104092793 4.366 Mapt
microtubule-associated protein tau
chr9_+_45178521 4.339 Fxyd6
FXYD domain-containing ion transport regulator 6
chr16_+_38089536 4.327 Gsk3b
glycogen synthase kinase 3 beta
chr4_-_109149274 4.319 Rnf11
ring finger protein 11
chr8_+_47556353 4.313 NM_007981
Acsl1
acyl-CoA synthetase long-chain family member 1
chr7_+_28438881 4.309 NM_028417
Ttc9b
tetratricopeptide repeat domain 9B
chrX_+_148578716 4.303 NM_001114664
Iqsec2
IQ motif and Sec7 domain 2
chr2_-_30997447 4.299 Fnbp1
formin binding protein 1
chr11_-_5965555 4.286 Camk2b
calcium/calmodulin-dependent protein kinase II, beta
chr4_-_134260127 4.278 NM_207237
Man1c1
mannosidase, alpha, class 1C, member 1
chr1_-_122017590 4.258 NM_007830
Dbi
diazepam binding inhibitor
chrX_+_97963061 4.246 NM_001177778
NM_016747
Dlg3

discs, large homolog 3 (Drosophila)

chr11_+_104092749 4.233 NM_001038609
NM_010838
Mapt

microtubule-associated protein tau

chrX_-_101396356 4.222 NM_001077354
C77370
expressed sequence C77370
chr5_+_81449776 4.173 Lphn3
latrophilin 3
chr2_+_16277924 4.167 NM_026162
Plxdc2
plexin domain containing 2
chr19_-_19185685 4.160 NM_001043354
Rorb
RAR-related orphan receptor beta
chr15_+_20378816 4.141


chr12_-_73509537 4.131 Rtn1
reticulon 1
chr10_+_115738429 4.112 NM_029928
Ptprb
protein tyrosine phosphatase, receptor type, B
chr10_-_76188683 4.094 NM_009933
Col6a1
collagen, type VI, alpha 1
chr2_+_32502107 4.081 NM_001146348
NM_001146350
NM_007932
Eng


endoglin


chr12_-_73509925 4.060 NM_153457
Rtn1
reticulon 1
chr2_-_152777135 4.040 NM_145744
NM_001159376
Dusp15

dual specificity phosphatase-like 15

chr4_-_47004585 4.027 NM_001081141
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr1_-_108656198 4.024 NM_027534
Kdsr
3-ketodihydrosphingosine reductase
chr7_+_133966816 4.018 NM_029978
Fam57b
family with sequence similarity 57, member B
chr19_+_56796545 3.979 Adrb1
adrenergic receptor, beta 1
chr11_-_95448869 3.968 NM_033217
Ngfr
nerve growth factor receptor (TNFR superfamily, member 16)
chr19_+_26679649 3.966 NM_011416
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr16_+_41532938 3.953 Lsamp
limbic system-associated membrane protein
chr6_-_115944822 3.953 NM_026376
Plxnd1
plexin D1
chr9_+_58430031 3.899 NM_009145
Nptn
neuroplastin
chr12_+_117724239 3.884 Ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr11_+_104092789 3.868 Mapt
microtubule-associated protein tau
chr10_+_90039435 3.863 NM_001177396
NM_001177398
NM_181398
Ipw
Anks1b


imprinted gene in the Prader-Willi syndrome region
ankyrin repeat and sterile alpha motif domain containing 1B


chr7_+_51846254 3.839 NM_008422
Kcnc3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr8_-_125777949 3.818 NM_028200
1300018I17Rik
RIKEN cDNA 1300018I17 gene
chr2_-_30997508 3.812 NM_001038700
NM_001177648
NM_001177649
NM_019406
Fnbp1



formin binding protein 1



chr11_+_3414792 3.790 Selm
selenoprotein M
chr1_-_84692750 3.779 NM_152915
Dner
delta/notch-like EGF-related receptor
chr17_+_36116923 3.765 Gnl1
guanine nucleotide binding protein-like 1
chr10_+_122116066 3.761 Ppm1h
protein phosphatase 1H (PP2C domain containing)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
2.86 3.62e-13 GO:0006811 ion transport
1.89 5.32e-13 GO:0006810 transport
2.44 1.58e-12 GO:0007399 nervous system development
1.86 2.43e-12 GO:0051234 establishment of localization
1.75 8.21e-12 GO:0051179 localization
4.40 1.17e-11 GO:0007268 synaptic transmission
3.05 4.24e-11 GO:0006812 cation transport
3.21 1.26e-10 GO:0030001 metal ion transport
3.66 1.31e-09 GO:0019226 transmission of nerve impulse
3.66 1.31e-09 GO:0035637 multicellular organismal signaling
4.55 6.84e-09 GO:0050804 regulation of synaptic transmission
1.77 1.72e-08 GO:0048731 system development
3.21 1.76e-08 GO:0007267 cell-cell signaling
2.47 2.07e-08 GO:0022008 neurogenesis
2.52 2.87e-08 GO:0048699 generation of neurons
2.05 3.06e-08 GO:0023051 regulation of signaling
4.22 4.82e-08 GO:0051969 regulation of transmission of nerve impulse
2.22 6.64e-08 GO:0010646 regulation of cell communication
4.01 8.46e-08 GO:0031644 regulation of neurological system process
1.87 2.42e-07 GO:0065008 regulation of biological quality
1.66 6.96e-07 GO:0048856 anatomical structure development
2.16 1.08e-06 GO:0032879 regulation of localization
2.98 1.50e-06 GO:0044057 regulation of system process
3.28 2.44e-06 GO:0015672 monovalent inorganic cation transport
3.02 2.86e-06 GO:0007610 behavior
4.49 2.90e-06 GO:0006813 potassium ion transport
8.60 3.00e-06 GO:0007269 neurotransmitter secretion
2.34 4.44e-06 GO:0051049 regulation of transport
2.74 4.61e-06 GO:0050801 ion homeostasis
6.05 1.14e-05 GO:0048167 regulation of synaptic plasticity
2.40 1.43e-05 GO:0007154 cell communication
5.44 2.12e-05 GO:0006836 neurotransmitter transport
4.58 2.38e-05 GO:0007611 learning or memory
1.56 2.54e-05 GO:0007275 multicellular organismal development
2.61 2.82e-05 GO:0030030 cell projection organization
2.29 3.49e-05 GO:0055085 transmembrane transport
3.07 3.83e-05 GO:0034220 ion transmembrane transport
2.40 4.08e-05 GO:0048878 chemical homeostasis
4.31 6.89e-05 GO:0050890 cognition
5.75 7.11e-05 GO:0001505 regulation of neurotransmitter levels
2.65 9.87e-05 GO:0006873 cellular ion homeostasis
2.46 1.09e-04 GO:0030182 neuron differentiation
2.58 1.94e-04 GO:0055082 cellular chemical homeostasis
1.49 2.38e-04 GO:0032502 developmental process
4.37 2.72e-04 GO:0010038 response to metal ion
1.78 2.83e-04 GO:0051239 regulation of multicellular organismal process
2.93 2.85e-04 GO:0055080 cation homeostasis
7.45 2.86e-04 GO:0048168 regulation of neuronal synaptic plasticity
2.09 3.28e-04 GO:0051128 regulation of cellular component organization
2.83 3.91e-04 GO:0031175 neuron projection development
6.24 6.39e-04 GO:0050808 synapse organization
3.44 8.60e-04 GO:0010035 response to inorganic substance
2.52 1.05e-03 GO:0048666 neuron development
3.10 1.10e-03 GO:0006875 cellular metal ion homeostasis
2.64 1.19e-03 GO:0071702 organic substance transport
3.13 1.50e-03 GO:0051129 negative regulation of cellular component organization
3.55 1.75e-03 GO:0060627 regulation of vesicle-mediated transport
4.27 1.80e-03 GO:0003001 generation of a signal involved in cell-cell signaling
4.27 1.80e-03 GO:0023061 signal release
2.28 2.26e-03 GO:0019725 cellular homeostasis
2.90 2.33e-03 GO:0030003 cellular cation homeostasis
2.97 2.40e-03 GO:0055065 metal ion homeostasis
3.43 3.09e-03 GO:0010975 regulation of neuron projection development
2.83 3.83e-03 GO:0045664 regulation of neuron differentiation
3.67 3.84e-03 GO:0006816 calcium ion transport
5.21 4.86e-03 GO:0017157 regulation of exocytosis
3.46 4.87e-03 GO:0046942 carboxylic acid transport
4.20 4.91e-03 GO:0006865 amino acid transport
1.58 5.24e-03 GO:0030154 cell differentiation
3.42 5.87e-03 GO:0015849 organic acid transport
1.77 6.74e-03 GO:0009966 regulation of signal transduction
8.03 7.88e-03 GO:0048169 regulation of long-term neuronal synaptic plasticity
3.09 9.13e-03 GO:0031344 regulation of cell projection organization
1.55 1.10e-02 GO:0048869 cellular developmental process
1.88 1.23e-02 GO:0042592 homeostatic process
2.52 1.39e-02 GO:0050767 regulation of neurogenesis
3.49 1.46e-02 GO:0015837 amine transport
2.42 1.54e-02 GO:0051960 regulation of nervous system development
8.86 1.55e-02 GO:0016079 synaptic vesicle exocytosis
10.92 1.80e-02 GO:0007416 synapse assembly
6.24 1.91e-02 GO:0048489 synaptic vesicle transport
1.57 2.28e-02 GO:0042221 response to chemical stimulus
1.63 2.45e-02 GO:0065009 regulation of molecular function
2.32 2.52e-02 GO:0060284 regulation of cell development
3.09 2.53e-02 GO:0072511 divalent inorganic cation transport
2.97 2.72e-02 GO:0006874 cellular calcium ion homeostasis
2.07 3.02e-02 GO:0001932 regulation of protein phosphorylation
2.69 3.28e-02 GO:0048812 neuron projection morphogenesis
2.43 3.88e-02 GO:0051046 regulation of secretion
4.64 4.03e-02 GO:0071901 negative regulation of protein serine/threonine kinase activity
1.45 4.17e-02 GO:0048522 positive regulation of cellular process
2.88 4.23e-02 GO:0055074 calcium ion homeostasis
3.08 4.38e-02 GO:0071705 nitrogen compound transport
2.87 4.54e-02 GO:0072503 cellular divalent inorganic cation homeostasis
1.99 4.73e-02 GO:0042325 regulation of phosphorylation
2.69 4.91e-02 GO:0048667 cell morphogenesis involved in neuron differentiation

Gene overrepresentation in compartment category:

enrichment p-value GO term description
1.88 1.13e-20 GO:0005886 plasma membrane
1.86 3.08e-20 GO:0071944 cell periphery
4.03 6.79e-20 GO:0045202 synapse
4.55 1.02e-17 GO:0044456 synapse part
1.43 1.63e-16 GO:0016020 membrane
3.20 2.39e-13 GO:0043005 neuron projection
1.41 6.39e-11 GO:0044425 membrane part
2.24 1.88e-09 GO:0042995 cell projection
1.42 1.96e-09 GO:0031224 intrinsic to membrane
3.58 1.84e-08 GO:0030425 dendrite
1.40 2.90e-08 GO:0016021 integral to membrane
1.80 3.41e-07 GO:0044459 plasma membrane part
2.61 1.28e-06 GO:0016023 cytoplasmic membrane-bounded vesicle
2.15 2.33e-06 GO:0005624 membrane fraction
2.53 2.35e-06 GO:0031988 membrane-bounded vesicle
2.12 2.35e-06 GO:0005626 insoluble fraction
2.93 6.25e-06 GO:0044297 cell body
2.98 6.40e-06 GO:0043025 neuronal cell body
3.98 9.41e-06 GO:0045211 postsynaptic membrane
4.28 1.13e-05 GO:0019717 synaptosome
5.00 1.14e-05 GO:0008021 synaptic vesicle
2.23 1.26e-05 GO:0031410 cytoplasmic vesicle
2.17 1.59e-05 GO:0031982 vesicle
8.01 1.82e-05 GO:0042734 presynaptic membrane
1.12 2.11e-05 GO:0005623 cell
1.12 2.11e-05 GO:0044464 cell part
3.99 3.77e-05 GO:0030136 clathrin-coated vesicle
1.33 4.77e-05 GO:0044444 cytoplasmic part
1.87 5.26e-05 GO:0000267 cell fraction
3.68 7.30e-05 GO:0030135 coated vesicle
2.40 1.82e-04 GO:0009986 cell surface
2.91 3.13e-04 GO:0030424 axon
2.15 3.60e-04 GO:0030054 cell junction
1.22 6.23e-04 GO:0005737 cytoplasm
6.33 7.70e-04 GO:0043195 terminal button
3.75 7.72e-04 GO:0033267 axon part
4.48 3.60e-03 GO:0043679 axon terminus
2.94 7.31e-03 GO:0045121 membrane raft
4.16 7.77e-03 GO:0044306 neuron projection terminus
2.20 1.00e-02 GO:0044463 cell projection part
1.94 1.15e-02 GO:0005887 integral to plasma membrane
1.73 1.48e-02 GO:0044421 extracellular region part
2.34 1.50e-02 GO:0031012 extracellular matrix
4.35 2.45e-02 GO:0008076 voltage-gated potassium channel complex
4.35 2.45e-02 GO:0034705 potassium channel complex
3.95 2.67e-02 GO:0030426 growth cone
2.38 3.10e-02 GO:0005773 vacuole
2.83 3.12e-02 GO:0034702 ion channel complex
3.81 3.72e-02 GO:0030427 site of polarized growth
1.83 4.00e-02 GO:0031226 intrinsic to plasma membrane
1.69 4.03e-02 GO:0005794 Golgi apparatus

Gene overrepresentation in function category:

enrichment p-value GO term description
1.52 3.52e-13 GO:0005515 protein binding
2.76 3.42e-12 GO:0022891 substrate-specific transmembrane transporter activity
2.64 6.63e-12 GO:0022857 transmembrane transporter activity
2.43 1.07e-11 GO:0005215 transporter activity
2.58 1.41e-11 GO:0022892 substrate-specific transporter activity
2.78 1.58e-10 GO:0015075 ion transmembrane transporter activity
3.09 3.88e-10 GO:0008324 cation transmembrane transporter activity
3.19 4.74e-08 GO:0005216 ion channel activity
3.56 6.62e-08 GO:0022836 gated channel activity
3.12 9.15e-08 GO:0022838 substrate-specific channel activity
3.03 2.36e-07 GO:0015267 channel activity
3.02 2.55e-07 GO:0022803 passive transmembrane transporter activity
3.60 3.39e-07 GO:0005261 cation channel activity
3.72 2.83e-05 GO:0005244 voltage-gated ion channel activity
3.72 2.83e-05 GO:0022832 voltage-gated channel activity
1.19 3.87e-05 GO:0005488 binding
4.23 1.12e-04 GO:0005267 potassium channel activity
2.32 3.59e-04 GO:0005509 calcium ion binding
4.02 4.90e-04 GO:0005516 calmodulin binding
1.86 6.80e-04 GO:0005102 receptor binding
5.05 6.82e-04 GO:0005275 amine transmembrane transporter activity
3.78 1.19e-03 GO:0022843 voltage-gated cation channel activity
2.66 1.23e-03 GO:0022804 active transmembrane transporter activity
4.16 1.38e-03 GO:0019838 growth factor binding
5.08 4.07e-03 GO:0015171 amino acid transmembrane transporter activity
4.21 5.53e-03 GO:0005249 voltage-gated potassium channel activity
6.85 7.10e-03 GO:0015179 L-amino acid transmembrane transporter activity
2.40 1.79e-02 GO:0042578 phosphoric ester hydrolase activity
5.82 2.51e-02 GO:0019208 phosphatase regulator activity
3.76 3.71e-02 GO:0046943 carboxylic acid transmembrane transporter activity
14.55 4.03e-02 GO:0008191 metalloendopeptidase inhibitor activity
14.55 4.03e-02 GO:0048551 metalloenzyme inhibitor activity
6.37 4.04e-02 GO:0019888 protein phosphatase regulator activity
6.37 4.04e-02 GO:0035254 glutamate receptor binding
3.68 4.58e-02 GO:0005342 organic acid transmembrane transporter activity
1.98 4.72e-02 GO:0019904 protein domain specific binding