Motif ID: MZF1.p2

Z-value: 1.543

Transcription factors associated with MZF1.p2:

NameEntrezDescription
Mzf1 109889 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Mzf1chr7_-_13639862-0.019.6e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr1_-_170362278 7.383 Pbx1
pre B-cell leukemia transcription factor 1
chr2_-_60800904 6.995 Rbms1
RNA binding motif, single stranded interacting protein 1
chr5_-_133019090 6.571


chr10_+_126515962 6.356 NM_001033263
Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr3_-_143865162 6.347 NM_001161770
NM_001161769
Lmo4

LIM domain only 4

chr1_-_170362298 5.618 Pbx1
pre B-cell leukemia transcription factor 1
chr2_-_60801248 5.608 NM_020296
Rbms1
RNA binding motif, single stranded interacting protein 1
chr7_-_81158546 5.349 NM_009181
St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr7_+_133966816 5.294 NM_029978
Fam57b
family with sequence similarity 57, member B
chr11_+_23978110 5.161 Bcl11a
B-cell CLL/lymphoma 11A (zinc finger protein)
chr7_+_152024499 4.954 NM_008007
Fgf3
fibroblast growth factor 3
chr2_+_37372112 4.924 NM_177383
Gpr21
G protein-coupled receptor 21
chr1_-_125942073 4.654 NM_199021
Dpp10
dipeptidylpeptidase 10
chr13_+_83663817 4.646 Mef2c
myocyte enhancer factor 2C
chr3_+_156224757 4.496 NM_001039094
NM_177274
Negr1

neuronal growth regulator 1

chr3_+_105507516 4.368 NM_175398
6530418L21Rik
RIKEN cDNA 6530418L21 gene
chr14_-_55735399 4.296 Jph4
junctophilin 4
chr3_+_45182311 4.296 NM_001098170
NM_001098171
NM_001098172
NM_011043
Pcdh10



protocadherin 10



chr10_-_126971614 4.000 NM_183297
Nxph4
neurexophilin 4
chrX_-_69901382 3.998 NM_008067
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr7_+_53040723 3.987 Lmtk3
lemur tyrosine kinase 3
chr11_+_98603186 3.744 NM_178060
Thra
thyroid hormone receptor alpha
chr5_-_133019167 3.742 Auts2
autism susceptibility candidate 2
chrX_+_130939318 3.738 NM_010078
Drp2
dystrophin related protein 2
chr1_-_157264398 3.728 NM_011273
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr11_+_69831951 3.690 NM_001109752
NM_007864
Dlg4

discs, large homolog 4 (Drosophila)

chr19_-_59150001 3.629 4930506M07Rik
RIKEN cDNA 4930506M07 gene
chrX_+_117403867 3.513 NM_001081385
Pcdh11x
protocadherin 11 X-linked
chrX_+_33735898 3.513 NM_028325
Zcchc12
zinc finger, CCHC domain containing 12
chr10_-_127057998 3.420 Lrp1
low density lipoprotein receptor-related protein 1
chr11_-_98190774 3.394 NM_010895
Neurod2
neurogenic differentiation 2
chr8_+_65430028 3.279 NM_023689
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr9_+_118387306 3.261 NM_001164789
NM_010136
Eomes

eomesodermin homolog (Xenopus laevis)

chrX_-_131745187 3.127 NM_025355
Tceal6
transcription elongation factor A (SII)-like 6
chr8_+_115093942 3.127 NM_130457
Cntnap4
contactin associated protein-like 4
chr5_+_151062363 3.126 NM_172887
Fry
furry homolog (Drosophila)
chr9_+_40076800 3.110 NM_001083917
NM_153522
NM_178227
Scn3b


sodium channel, voltage-gated, type III, beta


chr2_-_162486792 3.099 Ptprt
protein tyrosine phosphatase, receptor type, T
chr15_+_97998282 3.093 AI836003
expressed sequence AI836003
chr11_-_102157904 2.967 NM_001098836
NM_001098837
Atxn7l3

ataxin 7-like 3

chr6_+_110595574 2.929 Grm7
glutamate receptor, metabotropic 7
chr6_-_124813970 2.922 Gpr162
G protein-coupled receptor 162
chr2_-_153270059 2.894 NM_001001986
8430427H17Rik
RIKEN cDNA 8430427H17 gene
chr19_-_7557678 2.825 Rtn3
reticulon 3
chr1_+_160292470 2.707 NM_007495
Astn1
astrotactin 1
chr1_+_131170034 2.650 Thsd7b
thrombospondin, type I, domain containing 7B
chr18_+_38115192 2.645 NM_153793
Rell2
RELT-like 2
chr10_-_108447674 2.587 NM_009306
Syt1
synaptotagmin I
chr2_+_90725895 2.514 NM_026161
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr7_+_134094045 2.492 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr7_-_85722668 2.490 NM_008746
NM_182809
Ntrk3

neurotrophic tyrosine kinase, receptor, type 3

chr1_-_84281164 2.455 NM_001003948
Pid1
phosphotyrosine interaction domain containing 1
chr5_+_126012784 2.451 NM_001190352
Tmem132b
transmembrane protein 132B
chrX_-_98615096 2.447 NM_001177985
NM_001177986
Zmym3

zinc finger, MYM-type 3

chr6_-_136123091 2.386 Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr19_+_6497834 2.359


chr1_-_94998418 2.345 NM_001110315
NM_008440
Kif1a

kinesin family member 1A

chr2_-_113057218 2.332 Ryr3
ryanodine receptor 3
chr14_+_67530044 2.309 NM_175498
Pnma2
paraneoplastic antigen MA2
chr16_-_42340613 2.282 NM_008083
Gap43
growth associated protein 43
chr5_+_58109278 2.279 Pcdh7
protocadherin 7
chr6_+_45010040 2.250 NM_001004357
Cntnap2
contactin associated protein-like 2
chr4_+_13678443 2.243 NM_001111027
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_-_91492065 2.214 NM_020252
NM_177284
Nrxn1

neurexin I

chr8_+_68141935 2.200 NM_001166372
March1
membrane-associated ring finger (C3HC4) 1
chr11_-_74537303 2.194 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr8_-_105308910 2.191 NM_009866
Cdh11
cadherin 11
chr6_-_113841295 2.186 Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr16_-_88290458 2.183 NM_010348
NM_146072
Grik1

glutamate receptor, ionotropic, kainate 1

chr9_+_110147867 2.138 Cspg5
chondroitin sulfate proteoglycan 5
chr15_-_25343483 2.127 NM_027395
Basp1
brain abundant, membrane attached signal protein 1
chrX_-_71126088 2.116 NM_008478
L1cam
L1 cell adhesion molecule
chr18_-_16967100 2.115 Cdh2
cadherin 2
chr2_+_132607013 2.111 NM_007694
Chgb
chromogranin B
chr3_+_95985065 2.083 NM_022030
Sv2a
synaptic vesicle glycoprotein 2 a
chr3_+_53959956 2.081 NM_016984
Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr2_+_156439426 2.079 NM_146128
Dlgap4
discs, large homolog-associated protein 4 (Drosophila)
chr18_+_86564229 2.074 NM_144946
Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr7_-_54387695 2.065 Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr11_+_98603041 2.051 Thra
thyroid hormone receptor alpha
chr14_+_77556622 2.035 NM_172813
Enox1
ecto-NOX disulfide-thiol exchanger 1
chr13_-_46060354 2.032 Atxn1
ataxin 1
chr3_-_143868114 2.030 Lmo4
LIM domain only 4
chr2_+_107130745 2.022 NM_021275
Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr3_+_28162135 2.014 NM_001163007
NM_001163008
NM_001163009
NM_026910
Tnik



TRAF2 and NCK interacting kinase



chr3_-_122322556 2.001 NM_001114665
NM_153118
Fnbp1l

formin binding protein 1-like

chr2_+_174155592 1.998 NM_001077510
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr2_+_118489015 1.995 Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr19_+_6418755 1.965 Nrxn2
neurexin II
chr11_+_102994627 1.964 NM_001130516
NM_001130515
NM_027658
Hexim2


hexamthylene bis-acetamide inducible 2


chr2_+_70400179 1.963 NM_008077
Gad1
glutamic acid decarboxylase 1
chr11_-_108205240 1.961 Prkca
protein kinase C, alpha
chr13_-_29043539 1.952 Sox4
SRY-box containing gene 4
chr11_-_108205199 1.948 NM_011101
Prkca
protein kinase C, alpha
chr14_-_40286236 1.938 NM_001190187
NM_001190188
NM_008734
Nrg3


neuregulin 3


chr12_+_52694307 1.931 NM_001198835
NM_007728
Coch

coagulation factor C homolog (Limulus polyphemus)

chr11_-_97560852 1.923 Pcgf2
polycomb group ring finger 2
chr18_+_34407238 1.902 Apc
adenomatosis polyposis coli
chr7_-_52715059 1.895 NM_010240
Gm15590
Ftl1
Ftl2
ferritin light chain 1 pseudogene
ferritin light chain 1
ferritin light chain 2
chr7_+_25292375 1.868 Zfp428
zinc finger protein 428
chr11_+_23980676 1.829 NM_001159290
Bcl11a
B-cell CLL/lymphoma 11A (zinc finger protein)
chr19_-_17912073 1.828 NM_001163144
NM_001190483
Pcsk5

proprotein convertase subtilisin/kexin type 5

chr7_+_51565563 1.811 NM_001034115
Shank1
SH3/ankyrin domain gene 1
chr5_+_81449776 1.800 Lphn3
latrophilin 3
chr1_-_94998392 1.776 Kif1a
kinesin family member 1A
chrX_-_45245608 1.774 NM_053123
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr9_-_58052107 1.771 NM_001161541
Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr6_-_124813922 1.766 NM_013533
Gpr162
G protein-coupled receptor 162
chr4_+_138012860 1.757 Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr16_-_67621054 1.755 NM_001145977
NM_178721
Cadm2

cell adhesion molecule 2

chr10_-_80119815 1.745 NM_145361
Btbd2
BTB (POZ) domain containing 2
chr1_-_84281018 1.742 Pid1
phosphotyrosine interaction domain containing 1
chrX_+_132330678 1.739 Gprasp1
G protein-coupled receptor associated sorting protein 1
chr13_+_54472705 1.738 NM_009946
Cplx2
complexin 2
chr6_-_124813720 1.729 Gpr162
G protein-coupled receptor 162
chr17_-_32946797 1.720 NM_183177
Zfp811
zinc finger protein 811
chr1_-_64167818 1.716 Klf7
Kruppel-like factor 7 (ubiquitous)
chr17_-_11033034 1.710 NM_027032
Pacrg
PARK2 co-regulated
chr5_-_139605617 1.708 NM_008923
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr4_-_87679175 1.705 NM_027326
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_-_33226980 1.690 NM_175211
Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr5_-_38108301 1.687 NM_022416
Stk32b
serine/threonine kinase 32B
chr4_-_82151180 1.687 NM_001113209
NM_001113210
NM_008687
Nfib


nuclear factor I/B


chr4_-_68615382 1.685 NM_019967
Dbc1
deleted in bladder cancer 1 (human)
chr5_-_135028197 1.683 NM_001039162
NM_009990
Clip2

CAP-GLY domain containing linker protein 2

chr7_-_67242493 1.678 NM_001082961
Snrpn
small nuclear ribonucleoprotein N
chr6_+_105627738 1.674 NM_001109749
NM_173004
Cntn4

contactin 4

chr7_-_147268395 1.674 NM_001190385
NM_026769
Caly

calcyon neuron-specific vesicular protein

chr10_+_43298969 1.673 NM_009846
Cd24a
CD24a antigen
chr19_-_45857958 1.653 Mgea5
meningioma expressed antigen 5 (hyaluronidase)
chr2_+_27297997 1.651 D2Bwg1423e
DNA segment, Chr 2, Brigham & Women's Genetics 1423 expressed
chrX_-_35605544 1.651 Fam70a
family with sequence similarity 70, member A
chr1_+_148344816 1.648 NM_001145807
Fam5c
family with sequence similarity 5, member C
chr7_-_134968017 1.641 NM_024414
Stx1b
syntaxin 1B
chr6_+_91162792 1.640 Fbln2
fibulin 2
chr6_+_114232767 1.640 Slc6a1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr1_-_95375372 1.633 NM_133808
Hdlbp
high density lipoprotein (HDL) binding protein
chr4_+_130348406 1.612 NM_011520
Sdc3
syndecan 3
chr1_-_64167952 1.611 NM_033563
Klf7
Kruppel-like factor 7 (ubiquitous)
chr5_-_132014556 1.577 Auts2
autism susceptibility candidate 2
chr15_-_90509751 1.569 NM_001033851
NM_025815
Cpne8

copine VIII

chr19_+_27292039 1.569 Vldlr
very low density lipoprotein receptor
chr8_-_82581887 1.566 NM_020259
Hhip
Hedgehog-interacting protein
chrX_-_130223380 1.559 NM_001105245
NM_001105246
Pcdh19

protocadherin 19

chr13_-_36826245 1.559 NM_153529
Nrn1
neuritin 1
chr14_-_52533039 1.558 Ndrg2
N-myc downstream regulated gene 2
chr2_-_60800963 1.557 Rbms1
RNA binding motif, single stranded interacting protein 1
chr11_+_94871643 1.551 Samd14
sterile alpha motif domain containing 14
chrX_-_101017286 1.546 NM_009197
Slc16a2
solute carrier family 16 (monocarboxylic acid transporters), member 2
chr6_-_48395691 1.544 NM_001085417
NM_020589
Zfp467

zinc finger protein 467

chr5_-_138182307 1.543 6430598A04Rik
RIKEN cDNA 6430598A04 gene
chr13_-_55589377 1.534 NM_001177371
NM_001177372
NM_019813
Dbn1


drebrin 1


chr5_+_43625165 1.527 Cpeb2
cytoplasmic polyadenylation element binding protein 2
chrX_+_131291100 1.525 NM_027870
Armcx3
armadillo repeat containing, X-linked 3
chr1_+_131170053 1.514 Thsd7b
thrombospondin, type I, domain containing 7B
chr1_+_60466620 1.510 Abi2
abl-interactor 2
chr7_-_89079168 1.508 Hdgfrp3
hepatoma-derived growth factor, related protein 3
chr19_+_48280514 1.505 NM_025696
Sorcs3
sortilin-related VPS10 domain containing receptor 3
chr16_+_11984205 1.503 NM_001174086
NM_028277
Shisa9

shisa homolog 9 (Xenopus laevis)

chr16_+_8513513 1.500 NM_001170978
NM_172961
Abat

4-aminobutyrate aminotransferase

chr2_-_93797176 1.498 NM_001145034
Gm13889
predicted gene 13889
chr14_-_32249250 1.486 Sh3bp5
SH3-domain binding protein 5 (BTK-associated)
chr19_-_19185685 1.484 NM_001043354
Rorb
RAR-related orphan receptor beta
chr15_+_97998090 1.482 NM_177716
AI836003
expressed sequence AI836003
chr4_-_100937800 1.480 NM_146145
Jak1
Janus kinase 1
chr4_-_82151004 1.473 Nfib
nuclear factor I/B
chr1_+_160292665 1.470 Astn1
astrotactin 1
chr5_-_84846348 1.469 NM_007937
Epha5
Eph receptor A5
chr12_+_25659777 1.467 NM_001081378
Kidins220
kinase D-interacting substrate 220
chr2_-_33226946 1.464 Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr13_-_14615371 1.462 NM_001081348
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr13_-_40829082 1.433 NM_011547
Tcfap2a
transcription factor AP-2, alpha
chr7_-_25857275 1.424 NM_008168
Grik5
glutamate receptor, ionotropic, kainate 5 (gamma 2)
chr2_+_92439758 1.424 NM_023850
Chst1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr5_+_67067497 1.421 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr6_-_85452851 1.418 NM_001001160
Fbxo41
F-box protein 41
chr10_-_126497197 1.414 NM_001033262
March9
membrane-associated ring finger (C3HC4) 9
chr11_-_69651218 1.414 Nlgn2
neuroligin 2
chr9_+_64233432 1.412 NM_001134399
NM_172522
Megf11

multiple EGF-like-domains 11

chr14_-_35014818 1.411 NM_183209
Gprin2
G protein regulated inducer of neurite outgrowth 2
chr5_-_9725274 1.396 NM_181850
Grm3
glutamate receptor, metabotropic 3
chr1_-_107253012 1.392 Rnf152
ring finger protein 152
chr10_+_79630579 1.391 NM_007705
Cirbp
cold inducible RNA binding protein
chr7_+_4642681 1.390 Brsk1
BR serine/threonine kinase 1
chr4_-_68615283 1.388 Dbc1
deleted in bladder cancer 1 (human)
chr12_-_68323528 1.388 NM_001193266
NM_207010
Mdga2

MAM domain containing glycosylphosphatidylinositol anchor 2

chr4_+_144482979 1.386 NM_011303
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr7_+_107855215 1.384 NM_178764
Fam168a
family with sequence similarity 168, member A
chr7_+_107855164 1.378 Fam168a
family with sequence similarity 168, member A
chr13_+_19040215 1.365 NM_175007
Amph
amphiphysin
chr1_-_137406954 1.361 Nav1
neuron navigator 1
chr19_+_10116104 1.353 Fads3
fatty acid desaturase 3
chr8_+_12915892 1.353 NM_178076
Mcf2l
mcf.2 transforming sequence-like
chr7_+_6367885 1.350 NM_001134752
Gm16532
predicted gene, 16532
chr7_+_48888900 1.337 NM_023363
Zfp788
zinc finger protein 788
chr11_+_87574041 1.336 NM_172449
Bzrap1
benzodiazepine receptor associated protein 1
chr6_-_60778740 1.333 NM_001042451
Snca
synuclein, alpha
chr6_-_77929543 1.317 Ctnna2
catenin (cadherin associated protein), alpha 2
chr2_+_32006651 1.315 NM_001159634
NM_172661
Prrc2b

proline-rich coiled-coil 2B

chr1_-_193961641 1.315 NM_144814
Rcor3
REST corepressor 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
9.73 9.67e-19 GO:0007268 synaptic transmission
7.31 7.29e-18 GO:0007267 cell-cell signaling
7.70 9.94e-16 GO:0019226 transmission of nerve impulse
7.70 9.94e-16 GO:0035637 multicellular organismal signaling
3.73 2.02e-13 GO:0007399 nervous system development
4.97 2.73e-13 GO:0007154 cell communication
6.40 1.98e-12 GO:0007610 behavior
4.23 4.93e-11 GO:0048699 generation of neurons
4.07 7.67e-11 GO:0022008 neurogenesis
7.92 7.77e-11 GO:0031644 regulation of neurological system process
8.22 1.41e-10 GO:0051969 regulation of transmission of nerve impulse
8.44 3.35e-10 GO:0050804 regulation of synaptic transmission
10.84 3.41e-10 GO:0007611 learning or memory
5.59 5.03e-10 GO:0044057 regulation of system process
10.20 9.47e-10 GO:0050890 cognition
4.78 1.40e-09 GO:0030182 neuron differentiation
5.21 6.89e-09 GO:0048666 neuron development
2.36 1.51e-08 GO:0048731 system development
2.11 2.15e-08 GO:0032502 developmental process
2.12 1.34e-07 GO:0007275 multicellular organismal development
12.62 1.81e-07 GO:0048167 regulation of synaptic plasticity
1.75 4.72e-07 GO:0032501 multicellular organismal process
2.15 6.28e-07 GO:0048856 anatomical structure development
1.46 1.75e-06 GO:0065007 biological regulation
17.35 1.90e-06 GO:0048489 synaptic vesicle transport
2.62 2.38e-06 GO:0051239 regulation of multicellular organismal process
5.08 3.27e-06 GO:0031175 neuron projection development
2.33 4.24e-06 GO:0030154 cell differentiation
2.26 1.18e-05 GO:0048869 cellular developmental process
32.39 1.61e-05 GO:0048488 synaptic vesicle endocytosis
2.82 3.19e-05 GO:0010646 regulation of cell communication
2.31 3.33e-05 GO:0065008 regulation of biological quality
10.66 3.37e-05 GO:0001505 regulation of neurotransmitter levels
15.07 5.08e-05 GO:0048168 regulation of neuronal synaptic plasticity
3.04 6.71e-05 GO:0048468 cell development
1.44 1.35e-04 GO:0050794 regulation of cellular process
1.42 1.76e-04 GO:0050789 regulation of biological process
8.90 1.93e-04 GO:0006836 neurotransmitter transport
16.20 2.13e-04 GO:0060078 regulation of postsynaptic membrane potential
2.40 2.26e-04 GO:0023051 regulation of signaling
5.11 3.03e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
9.85 3.33e-04 GO:0007612 learning
3.30 3.42e-04 GO:0007155 cell adhesion
3.28 3.98e-04 GO:0022610 biological adhesion
3.64 4.10e-04 GO:0030030 cell projection organization
4.88 5.40e-04 GO:0048812 neuron projection morphogenesis
5.23 5.75e-04 GO:0007409 axonogenesis
18.00 8.42e-04 GO:0060079 regulation of excitatory postsynaptic membrane potential
7.43 1.05e-03 GO:0003001 generation of a signal involved in cell-cell signaling
7.43 1.05e-03 GO:0023061 signal release
12.88 1.10e-03 GO:0007269 neurotransmitter secretion
12.88 1.10e-03 GO:0051899 membrane depolarization
4.29 1.24e-03 GO:0000904 cell morphogenesis involved in differentiation
16.76 1.32e-03 GO:0048169 regulation of long-term neuronal synaptic plasticity
9.67 1.77e-03 GO:0017157 regulation of exocytosis
1.89 2.05e-03 GO:0048522 positive regulation of cellular process
1.97 2.40e-03 GO:0003008 system process
1.83 2.47e-03 GO:0048518 positive regulation of biological process
1.81 2.53e-03 GO:0016043 cellular component organization
2.03 2.65e-03 GO:0050877 neurological system process
2.51 3.68e-03 GO:0032879 regulation of localization
1.95 5.26e-03 GO:0071842 cellular component organization at cellular level
1.59 5.49e-03 GO:0023052 signaling
4.04 5.69e-03 GO:0048858 cell projection morphogenesis
3.96 7.21e-03 GO:0032990 cell part morphogenesis
2.21 8.52e-03 GO:0009653 anatomical structure morphogenesis
2.74 8.57e-03 GO:0051049 regulation of transport
5.79 1.02e-02 GO:0007626 locomotory behavior
1.74 1.03e-02 GO:0071840 cellular component organization or biogenesis
26.99 1.11e-02 GO:0034109 homotypic cell-cell adhesion
4.67 1.18e-02 GO:0016337 cell-cell adhesion
16.20 1.27e-02 GO:0007215 glutamate signaling pathway
3.76 1.32e-02 GO:0051046 regulation of secretion
11.04 1.69e-02 GO:0007270 nerve-nerve synaptic transmission
3.04 1.97e-02 GO:0051094 positive regulation of developmental process
3.29 2.02e-02 GO:0000902 cell morphogenesis
1.85 2.10e-02 GO:0071841 cellular component organization or biogenesis at cellular level
8.34 2.17e-02 GO:0007156 homophilic cell adhesion
1.22 2.79e-02 GO:0009987 cellular process
10.12 2.81e-02 GO:0008306 associative learning
10.12 2.81e-02 GO:0050806 positive regulation of synaptic transmission
13.50 3.25e-02 GO:0050805 negative regulation of synaptic transmission
9.72 3.57e-02 GO:0033555 multicellular organismal response to stress
40.49 3.87e-02 GO:0016188 synaptic vesicle maturation
40.49 3.87e-02 GO:0032229 negative regulation of synaptic transmission, GABAergic
40.49 3.87e-02 GO:2000300 regulation of synaptic vesicle exocytosis
20.25 3.92e-02 GO:0043113 receptor clustering
4.94 4.02e-02 GO:0060627 regulation of vesicle-mediated transport
6.29 4.41e-02 GO:0030534 adult behavior
1.65 4.46e-02 GO:0051179 localization
9.35 4.48e-02 GO:0051971 positive regulation of transmission of nerve impulse

Gene overrepresentation in compartment category:

enrichment p-value GO term description
6.42 6.73e-21 GO:0043005 neuron projection
6.28 5.74e-17 GO:0045202 synapse
8.41 3.55e-15 GO:0030424 axon
7.05 2.55e-14 GO:0044456 synapse part
3.78 9.32e-14 GO:0042995 cell projection
2.17 1.32e-12 GO:0071944 cell periphery
6.82 2.54e-11 GO:0030425 dendrite
2.13 2.68e-11 GO:0005886 plasma membrane
22.27 2.43e-10 GO:0042734 presynaptic membrane
9.82 1.39e-09 GO:0033267 axon part
9.53 2.20e-09 GO:0019717 synaptosome
5.54 1.69e-08 GO:0043025 neuronal cell body
5.27 4.28e-08 GO:0044297 cell body
3.18 2.40e-07 GO:0005626 insoluble fraction
7.55 2.71e-07 GO:0045211 postsynaptic membrane
3.23 2.76e-07 GO:0005624 membrane fraction
4.55 2.99e-07 GO:0044463 cell projection part
29.83 3.20e-07 GO:0008328 ionotropic glutamate receptor complex
10.61 1.21e-06 GO:0044306 neuron projection terminus
10.38 7.36e-06 GO:0043679 axon terminus
2.63 1.15e-05 GO:0000267 cell fraction
14.08 1.50e-05 GO:0043195 terminal button
3.32 2.91e-05 GO:0030054 cell junction
2.16 8.67e-05 GO:0044459 plasma membrane part
1.17 3.28e-04 GO:0005623 cell
1.17 3.28e-04 GO:0044464 cell part
60.73 1.34e-03 GO:0032983 kainate selective glutamate receptor complex
7.81 1.53e-03 GO:0014069 postsynaptic density
5.55 2.49e-03 GO:0030136 clathrin-coated vesicle
1.33 4.12e-03 GO:0016020 membrane
6.55 5.62e-03 GO:0008021 synaptic vesicle
7.56 7.00e-03 GO:0044309 neuron spine
4.88 7.55e-03 GO:0030135 coated vesicle
7.00 1.15e-02 GO:0030426 growth cone
6.75 1.45e-02 GO:0030427 site of polarized growth
4.93 1.70e-02 GO:0005938 cell cortex
30.37 1.80e-02 GO:0061200 clathrin sculpted gamma-aminobutyric acid transport vesicle
30.37 1.80e-02 GO:0061202 clathrin sculpted gamma-aminobutyric acid transport vesicle membrane
2.46 2.62e-02 GO:0031410 cytoplasmic vesicle
26.99 2.68e-02 GO:0060198 clathrin sculpted vesicle
2.49 3.16e-02 GO:0031226 intrinsic to plasma membrane
1.34 3.37e-02 GO:0044425 membrane part
2.51 4.28e-02 GO:0005887 integral to plasma membrane

Gene overrepresentation in function category:

enrichment p-value GO term description
1.74 2.70e-09 GO:0005515 protein binding
22.34 4.00e-07 GO:0008066 glutamate receptor activity
1.34 3.25e-06 GO:0005488 binding
25.31 2.63e-04 GO:0005234 extracellular-glutamate-gated ion channel activity
22.49 5.05e-04 GO:0004970 ionotropic glutamate receptor activity
7.22 1.08e-03 GO:0019207 kinase regulator activity
60.73 1.81e-03 GO:0015277 kainate selective glutamate receptor activity
3.66 2.18e-03 GO:0032403 protein complex binding
7.71 2.27e-03 GO:0019887 protein kinase regulator activity
8.86 3.33e-03 GO:0005230 extracellular ligand-gated ion channel activity
3.00 5.47e-03 GO:0019904 protein domain specific binding
2.50 6.29e-03 GO:0030234 enzyme regulator activity
40.49 8.89e-03 GO:0008187 poly-pyrimidine tract binding
20.25 9.00e-03 GO:0005246 calcium channel regulator activity
12.65 1.03e-02 GO:0035254 glutamate receptor binding
6.06 1.33e-02 GO:0015276 ligand-gated ion channel activity
6.06 1.33e-02 GO:0022834 ligand-gated channel activity
11.91 1.40e-02 GO:0003727 single-stranded RNA binding
4.50 2.02e-02 GO:0001664 G-protein-coupled receptor binding
16.20 2.30e-02 GO:0035255 ionotropic glutamate receptor binding
6.16 3.51e-02 GO:0030165 PDZ domain binding
80.97 3.74e-02 GO:0031852 mu-type opioid receptor binding