Motif ID: NFKB1_REL_RELA.p2

Z-value: 1.469

Transcription factors associated with NFKB1_REL_RELA.p2:

NameEntrezDescription
Nfkb1 18033 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
Rel 19696 reticuloendotheliosis oncogene
Rela 19697 v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Nfkb1chr3_-_1353541510.661.3e-05Click!
Relachr19_+_5637712-0.591.6e-04Click!
Relchr11_-_236707660.372.5e-02Click!


Activity profile for motif NFKB1_REL_RELA.p2.

activity profile for motif NFKB1_REL_RELA.p2


Sorted Z-values histogram for motif NFKB1_REL_RELA.p2

Sorted Z-values for motif NFKB1_REL_RELA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFKB1_REL_RELA.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Description
chr7_-_110991602 5.341 NM_008219
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr5_-_38215607 5.060 NM_010835
Msx1
homeobox, msh-like 1
chr11_+_98902556 4.609 NM_010517
Igfbp4
insulin-like growth factor binding protein 4
chr7_+_30074296 4.462 NM_026731
Ppp1r14a
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr11_+_94797565 4.450 NM_007742
Col1a1
collagen, type I, alpha 1
chr11_+_117710532 4.151 NM_001012273
NM_009689
Birc5

baculoviral IAP repeat-containing 5

chr6_+_125045998 3.624 NM_145979
Chd4
chromodomain helicase DNA binding protein 4
chr10_-_115024814 3.595 NM_010195
Lgr5
leucine rich repeat containing G protein coupled receptor 5
chr5_-_106887469 3.244 Barhl2
BarH-like 2 (Drosophila)
chr10_-_76188683 3.236 NM_009933
Col6a1
collagen, type VI, alpha 1
chr11_-_95867076 3.163 NM_009951
Igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr2_-_165060188 3.108 NM_174988
Cdh22
cadherin 22
chr17_-_34137221 3.068 NM_001001892
H2-K1
histocompatibility 2, K1, K region
chr3_+_104442568 3.059 NM_009196
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr4_+_124663673 3.040 NM_138683
Rspo1
R-spondin homolog (Xenopus laevis)
chr10_+_25079661 2.844 Epb4.1l2
erythrocyte protein band 4.1-like 2
chr2_+_14151018 2.794 NM_008625
Mrc1
mannose receptor, C type 1
chr14_-_71041964 2.698 NM_008004
Fgf17
fibroblast growth factor 17
chr13_+_51740600 2.693 NM_025415
Cks2
CDC28 protein kinase regulatory subunit 2
chr6_+_117867280 2.661 NM_001166427
Hnrnpf
heterogeneous nuclear ribonucleoprotein F
chr6_+_134870680 2.601 Cdkn1b
cyclin-dependent kinase inhibitor 1B
chr7_+_3290516 2.597 NM_016969
NM_001093765
Myadm

myeloid-associated differentiation marker

chr15_-_78994753 2.536 NM_011437
Sox10
SRY-box containing gene 10
chr3_-_135354151 2.484 Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
chr10_+_23943322 2.483 NM_021509
Moxd1
monooxygenase, DBH-like 1
chr17_-_34764290 2.477 Ppt2
palmitoyl-protein thioesterase 2
chr7_-_109398578 2.431 NM_019566
Rhog
ras homolog gene family, member G
chr19_+_45092581 2.421 NM_001130526
Lzts2
leucine zipper, putative tumor suppressor 2
chr1_-_75502814 2.398 Obsl1
obscurin-like 1
chr14_-_62301012 2.339 Dleu2
deleted in lymphocytic leukemia, 2
chr6_+_42300005 2.321 Zyx
zyxin
chr3_+_40603872 2.257 NM_011495
Plk4
polo-like kinase 4 (Drosophila)
chr3_+_127336055 2.214 NM_009718
Neurog2
neurogenin 2
chr2_+_10075242 2.213 Itih5
inter-alpha (globulin) inhibitor H5
chr4_-_123089122 2.210 NM_001167918
D830031N03Rik
RIKEN cDNA D830031N03 gene
chr11_-_96838940 2.201 NM_001080964
NM_030220
Sp2

Sp2 transcription factor

chr11_+_43342241 2.182 NM_001045530
Ccnjl
cyclin J-like
chr4_-_117169519 2.179 NM_025739
Rnf220
ring finger protein 220
chr5_-_137971968 2.134 Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr4_+_47220883 2.102 NM_009928
Col15a1
collagen, type XV, alpha 1
chr4_-_116806403 2.096 NM_013807
Plk3
polo-like kinase 3 (Drosophila)
chr2_-_165060352 2.096 Cdh22
cadherin 22
chr11_+_69393851 2.085 NM_001127233
NM_011640
Trp53

transformation related protein 53

chr9_+_60642248 2.035 NM_028283
Uaca
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr1_-_173957316 1.985 NM_033509
Vangl2
vang-like 2 (van gogh, Drosophila)
chr11_+_98798970 1.972 NM_009024
Rara
retinoic acid receptor, alpha
chr11_-_93747039 1.970 NM_001013375
Utp18
UTP18, small subunit (SSU) processome component, homolog (yeast)
chr10_+_79642100 1.961 NM_007909
Efna2
ephrin A2
chr3_+_122432075 1.959 NM_153422
Pde5a
phosphodiesterase 5A, cGMP-specific
chr1_+_64579358 1.945 NM_001037726
NM_009952
NM_133828
Creb1


cAMP responsive element binding protein 1


chr4_+_126234210 1.940 NM_175554
Clspn
claspin homolog (Xenopus laevis)
chr11_+_98799013 1.932 NM_001177302
Rara
retinoic acid receptor, alpha
chr8_+_47825098 1.926 NM_008391
Irf2
interferon regulatory factor 2
chr16_+_72663393 1.911 NM_019413
Robo1
roundabout homolog 1 (Drosophila)
chr9_-_21657048 1.910 NM_177030
Dock6
dedicator of cytokinesis 6
chr12_+_119082333 1.848 NM_146040
Cdca7l
cell division cycle associated 7 like
chr3_-_57379600 1.845 NM_133784
Wwtr1
WW domain containing transcription regulator 1
chr2_+_119568028 1.844 NM_146125
Itpka
inositol 1,4,5-trisphosphate 3-kinase A
chr4_+_137024656 1.843 NM_008305
Hspg2
perlecan (heparan sulfate proteoglycan 2)
chr6_-_127075853 1.840 Ccnd2
cyclin D2
chr12_+_104553168 1.840 NM_001195726
Fam181a
family with sequence similarity 181, member A
chr3_-_126701367 1.839 NM_178655
Ank2
ankyrin 2, brain
chr2_+_10075220 1.822 Itih5
inter-alpha (globulin) inhibitor H5
chr15_-_97923632 1.803 NM_144851
Senp1
SUMO1/sentrin specific peptidase 1
chr7_+_3290587 1.780 Myadm
myeloid-associated differentiation marker
chr9_-_61794540 1.755 NM_024245
Kif23
kinesin family member 23
chr15_-_103045710 1.752 NM_001110216
NM_007626
Cbx5

chromobox homolog 5 (Drosophila HP1a)

chr14_-_118636251 1.746 NM_177753
Sox21
SRY-box containing gene 21
chr2_-_174264400 1.734 NM_022325
Ctsz
cathepsin Z
chr3_-_8666930 1.731 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr11_+_53333270 1.731 NM_033144
Sept8
septin 8
chr13_+_75844950 1.724 Ell2
elongation factor RNA polymerase II 2
chr19_-_12869863 1.706 Zfp91
zinc finger protein 91
chr15_+_98620287 1.691 NM_021279
Wnt1
wingless-related MMTV integration site 1
chr11_-_106134024 1.691 NM_001130187
Smarcd2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr6_+_48791481 1.674 NM_025326
Tmem176a
transmembrane protein 176A
chr2_+_120393393 1.653 NM_001177792
NM_001177793
NM_009222
Snap23


synaptosomal-associated protein 23


chr7_-_29383163 1.583 Pak4
p21 protein (Cdc42/Rac)-activated kinase 4
chr19_+_8963366 1.581 NM_025463
1810009A15Rik
RIKEN cDNA 1810009A15 gene
chr5_-_92512486 1.578 NM_001080794
NM_001080796
G3bp2

GTPase activating protein (SH3 domain) binding protein 2

chr2_+_156665812 1.575 NM_173396
Tgif2
TGFB-induced factor homeobox 2
chr9_-_106101461 1.562 NM_026447
Ppm1m
protein phosphatase 1M
chr5_-_137592066 1.559 NM_201373
Trim56
tripartite motif-containing 56
chr11_-_75841236 1.557 NM_029658
Fam101b
family with sequence similarity 101, member B
chr11_-_68200284 1.555 NM_008744
Ntn1
netrin 1
chr1_-_42749940 1.552 2610017I09Rik
RIKEN cDNA 2610017I09 gene
chr9_-_44543245 1.551 NM_153537
Phldb1
pleckstrin homology-like domain, family B, member 1
chr4_+_114761644 1.548 Pdzk1ip1
PDZK1 interacting protein 1
chr10_-_68815606 1.548 NM_007659
Cdk1
cyclin-dependent kinase 1
chr2_-_101637773 1.538 NM_001083810
NM_175181
Prr5l

proline rich 5 like

chr7_+_26471968 1.538 NM_011577
Tgfb1
transforming growth factor, beta 1
chr18_+_50139080 1.538 NM_001177759
NM_001177760
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr19_-_36994088 1.528 NM_028263
Fgfbp3
fibroblast growth factor binding protein 3
chr17_+_35400038 1.515 NM_010380
H2-D1
histocompatibility 2, D region locus 1
chr12_-_11272479 1.507 NM_177331
Gen1
Gen homolog 1, endonuclease (Drosophila)
chr1_-_135975681 1.497 NM_007570
Btg2
B-cell translocation gene 2, anti-proliferative
chr9_+_110034489 1.477 NM_009211
Smarcc1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr3_-_51144470 1.471 Elf2
E74-like factor 2
chr9_+_109778051 1.464 NM_007658
Cdc25a
cell division cycle 25 homolog A (S. pombe)
chr14_-_70919701 1.459 Bmp1
bone morphogenetic protein 1
chr2_-_125332107 1.428 NM_007993
Fbn1
fibrillin 1
chr3_+_66023808 1.397 NM_008987
Ptx3
pentraxin related gene
chr17_+_28938070 1.391 NM_001081315
Brpf3
bromodomain and PHD finger containing, 3
chr7_+_52273317 1.384 NM_009101
Rras
Harvey rat sarcoma oncogene, subgroup R
chr15_-_82075137 1.381 NM_025639
NM_178269
Cenpm

centromere protein M

chr17_+_35187185 1.376 NM_033444
Clic1
chloride intracellular channel 1
chr19_+_46576230 1.373 Trim8
tripartite motif-containing 8
chr4_+_100449375 1.362 Cachd1
cache domain containing 1
chr10_-_8238569 1.361 NM_177387
Ust
uronyl-2-sulfotransferase
chr9_+_108998083 1.354 Plxnb1
plexin B1
chr16_-_78376912 1.337 NM_009770
Btg3
B-cell translocation gene 3
chr2_-_164268672 1.328 NM_011521
Sdc4
syndecan 4
chr17_+_35187325 1.325 Clic1
chloride intracellular channel 1
chr6_-_39156609 1.322 Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr1_-_75503026 1.307 NM_178884
Obsl1
obscurin-like 1
chr1_-_165242744 1.285 Prrx1
paired related homeobox 1
chr5_-_89105135 1.280 NM_178700
Grsf1
G-rich RNA sequence binding factor 1
chr2_+_119444452 1.267 Nusap1
nucleolar and spindle associated protein 1
chr2_+_164388211 1.264 NM_026323
Wfdc2
WAP four-disulfide core domain 2
chr3_+_66023884 1.263 Ptx3
pentraxin related gene
chr7_-_52308243 1.259 NM_175022
Prr12
proline rich 12
chr6_+_134870418 1.245 NM_009875
Cdkn1b
cyclin-dependent kinase inhibitor 1B
chr5_+_137791368 1.244 Ephb4
Eph receptor B4
chr13_-_112280018 1.226 NM_001122963
NM_028487
Gpbp1

GC-rich promoter binding protein 1

chr17_+_45823255 1.193 NM_026732
Mrpl14
mitochondrial ribosomal protein L14
chr7_+_106683983 1.192 NM_177231
NM_178220
Arrb1

arrestin, beta 1

chr11_+_61890494 1.188 NM_001029936
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr2_-_37278415 1.187 NM_001100591
Rc3h2
ring finger and CCCH-type zinc finger domains 2
chr10_-_127648817 1.184 NM_025716
Spryd4
SPRY domain containing 4
chr17_-_35838974 1.180 NM_001198831
Ddr1
discoidin domain receptor family, member 1
chr18_+_58038278 1.179 NM_009194
Slc12a2
solute carrier family 12, member 2
chr3_-_116126932 1.178 NM_001080818
NM_001173553
Cdc14a

CDC14 cell division cycle 14 homolog A (S. cerevisiae)

chr5_+_91201521 1.171 Pf4
platelet factor 4
chr16_-_11254052 1.170 NM_001130008
NM_146066
Gspt1

G1 to S phase transition 1

chr19_+_55816320 1.161 Tcf7l2
transcription factor 7-like 2, T-cell specific, HMG-box
chr12_+_80130149 1.149 NM_181073
Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr3_+_30993952 1.133 NM_001039090
NM_011386
Skil

SKI-like

chr3_+_89225539 1.132 NM_001113331
Shc1
src homology 2 domain-containing transforming protein C1
chr12_+_112776539 1.127 Eif5
eukaryotic translation initiation factor 5
chr14_+_56503783 1.126 NM_027143
Khnyn
KH and NYN domain containing
chr19_-_10278231 1.117 NM_007999
Fen1
flap structure specific endonuclease 1
chr5_+_137791332 1.116 NM_001159571
NM_010144
Ephb4

Eph receptor B4

chr5_+_112772106 1.115 NM_138646
Hps4
Hermansky-Pudlak syndrome 4 homolog (human)
chr6_+_47403899 1.110 Cul1
cullin 1
chr19_+_6341137 1.109 NM_009006
Map4k2
mitogen-activated protein kinase kinase kinase kinase 2
chr19_-_46380070 1.107 4833438C02Rik
RIKEN cDNA 4833438C02 gene
chr3_-_117571789 1.101 Snx7
sorting nexin 7
chr10_+_7445867 1.101 Katna1
katanin p60 (ATPase-containing) subunit A1
chr7_-_31241977 1.094 Kirrel2
kin of IRRE like 2 (Drosophila)
chr11_-_95448869 1.093 NM_033217
Ngfr
nerve growth factor receptor (TNFR superfamily, member 16)
chr18_-_67884185 1.084 NM_001127177
NM_008977
Ptpn2

protein tyrosine phosphatase, non-receptor type 2

chr10_+_25079603 1.083 Epb4.1l2
erythrocyte protein band 4.1-like 2
chr9_-_72339762 1.081 NM_009359
Tex9
testis expressed gene 9
chr8_-_72519966 1.080 NM_001113345
NM_145596
Gatad2a

GATA zinc finger domain containing 2A

chr2_-_4984983 1.078 NM_181848
Optn
optineurin
chr17_-_80295336 1.059 NM_019717
NM_178050
Atl2

atlastin GTPase 2

chr7_-_86611065 1.055 NM_017462
Polg
polymerase (DNA directed), gamma
chr10_+_126817878 1.042


chr10_+_5958432 1.039 NM_001033466
Zbtb2
zinc finger and BTB domain containing 2
chr9_-_123587923 1.035 NM_139142
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr17_-_46841851 1.035 Ppp2r5d
protein phosphatase 2, regulatory subunit B (B56), delta isoform
chr14_+_56503830 1.029 Khnyn
KH and NYN domain containing
chr19_-_4439350 1.026 NM_007485
Rhod
ras homolog gene family, member D
chr8_+_124900542 1.020 Zc3h18
zinc finger CCCH-type containing 18
chr1_-_154749751 1.020 NM_001005507
NM_001160256
Smg7

Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)

chr12_+_114394594 1.012 NM_134041
4930427A07Rik
RIKEN cDNA 4930427A07 gene
chr3_+_135101664 1.005 NM_025356
Ube2d3
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chrX_-_7000037 1.005 2010204K13Rik
RIKEN cDNA 2010204K13 gene
chr19_-_40345985 1.003 Pdlim1
PDZ and LIM domain 1 (elfin)
chr4_+_107040647 1.003 Tmem48
transmembrane protein 48
chr1_+_182499015 0.993 Parp1
poly (ADP-ribose) polymerase family, member 1
chr6_-_134847832 0.988 NM_001167695
NM_001167696
NM_001167693
NM_001167694
NM_001167700
Gpr19




G protein-coupled receptor 19




chr16_+_4594742 0.982 Glis2
GLIS family zinc finger 2
chr8_-_124956759 0.981 NM_007806
Cyba
cytochrome b-245, alpha polypeptide
chr7_+_30023368 0.978 Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr15_-_102181072 0.977 NM_153416
Aaas
achalasia, adrenocortical insufficiency, alacrimia
chr12_-_99816091 0.974 NM_029911
Kcnk10
potassium channel, subfamily K, member 10
chr8_-_123191878 0.971 NM_010926
Cox4nb
COX4 neighbor
chr19_+_39361574 0.970 NM_007815
Cyp2c29
cytochrome P450, family 2, subfamily c, polypeptide 29
chr6_-_39156706 0.969 NM_001033430
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chrX_+_149441011 0.968 NM_001137547
Usp51
ubiquitin specific protease 51
chr7_-_77511242 0.964 Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr14_-_46149660 0.964 NM_146054
Fermt2
fermitin family homolog 2 (Drosophila)
chr2_-_119444196 0.963 NM_001042653
Oip5
Opa interacting protein 5
chr11_-_102226419 0.961 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr3_-_8667013 0.959 NM_010423
Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr15_-_77949709 0.951 NM_007583
Cacng2
calcium channel, voltage-dependent, gamma subunit 2
chr9_-_63605745 0.944 NM_016769
Smad3
MAD homolog 3 (Drosophila)
chr11_-_54769546 0.944 Tnip1
TNFAIP3 interacting protein 1
chr4_-_91066674 0.942 NM_207685
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr11_+_23156482 0.940 Xpo1
exportin 1, CRM1 homolog (yeast)
chr4_-_59796621 0.933 NM_001013577
1110054O05Rik
RIKEN cDNA 1110054O05 gene
chr4_+_43970559 0.929 NM_027450
Glipr2
GLI pathogenesis-related 2
chr17_-_28487544 0.926 NM_001098226
NM_011566
Tead3

TEA domain family member 3

chr3_-_65762057 0.925 NM_019937
Ccnl1
cyclin L1
chr10_-_79502432 0.925 Polr2e
polymerase (RNA) II (DNA directed) polypeptide E
chr7_+_132695758 0.920 NM_001008700
Il4ra
interleukin 4 receptor, alpha
chr17_-_84587278 0.919 NM_001001806
Zfp36l2
zinc finger protein 36, C3H type-like 2
chrX_-_149204003 0.918 NM_172441
Shroom2
shroom family member 2
chr10_+_98725871 0.917 Dusp6
dual specificity phosphatase 6

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
7.08 8.23e-08 GO:0051130 positive regulation of cellular component organization
2.62 2.37e-07 GO:0048522 positive regulation of cellular process
2.50 2.37e-07 GO:0048518 positive regulation of biological process
6.06 1.01e-06 GO:0060284 regulation of cell development
4.02 5.49e-06 GO:0051128 regulation of cellular component organization
10.51 7.73e-06 GO:0010720 positive regulation of cell development
5.80 1.66e-05 GO:0051960 regulation of nervous system development
6.08 2.57e-05 GO:0050767 regulation of neurogenesis
5.43 4.20e-05 GO:0045597 positive regulation of cell differentiation
3.91 4.25e-05 GO:0045595 regulation of cell differentiation
4.65 6.09e-05 GO:0051094 positive regulation of developmental process
3.36 8.54e-05 GO:0050793 regulation of developmental process
9.03 1.60e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
9.03 1.60e-04 GO:0022604 regulation of cell morphogenesis
3.48 3.10e-04 GO:2000026 regulation of multicellular organismal development
1.90 4.97e-04 GO:0019222 regulation of metabolic process
1.99 6.58e-04 GO:0060255 regulation of macromolecule metabolic process
2.26 6.64e-04 GO:0048731 system development
3.60 6.70e-04 GO:0048699 generation of neurons
2.52 7.96e-04 GO:0048513 organ development
2.96 9.46e-04 GO:0007399 nervous system development
2.76 1.24e-03 GO:0009653 anatomical structure morphogenesis
2.14 1.34e-03 GO:0010468 regulation of gene expression
4.44 1.43e-03 GO:0051726 regulation of cell cycle
3.28 1.57e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
2.15 1.57e-03 GO:0010556 regulation of macromolecule biosynthetic process
4.68 1.80e-03 GO:0032583 regulation of gene-specific transcription
3.37 1.83e-03 GO:0022008 neurogenesis
2.64 1.91e-03 GO:0051239 regulation of multicellular organismal process
3.33 2.22e-03 GO:0010628 positive regulation of gene expression
2.15 2.24e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
3.19 2.35e-03 GO:0042127 regulation of cell proliferation
4.89 2.61e-03 GO:0007167 enzyme linked receptor protein signaling pathway
2.05 2.64e-03 GO:0016043 cellular component organization
2.52 2.88e-03 GO:0048583 regulation of response to stimulus
2.18 3.26e-03 GO:0051252 regulation of RNA metabolic process
1.69 3.27e-03 GO:0043170 macromolecule metabolic process
2.01 3.31e-03 GO:0071840 cellular component organization or biogenesis
21.10 3.34e-03 GO:0060603 mammary gland duct morphogenesis
2.07 3.89e-03 GO:0048856 anatomical structure development
3.17 4.75e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.44 4.78e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
3.05 4.85e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.72 5.32e-03 GO:0044260 cellular macromolecule metabolic process
1.87 5.40e-03 GO:0031323 regulation of cellular metabolic process
2.05 5.40e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.00 6.35e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
5.37 6.50e-03 GO:0045664 regulation of neuron differentiation
2.99 6.56e-03 GO:0009891 positive regulation of biosynthetic process
3.09 6.88e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
2.03 6.97e-03 GO:0051171 regulation of nitrogen compound metabolic process
3.90 7.05e-03 GO:0008284 positive regulation of cell proliferation
1.98 7.17e-03 GO:0007275 multicellular organismal development
2.20 7.24e-03 GO:0048523 negative regulation of cellular process
2.01 8.63e-03 GO:0009889 regulation of biosynthetic process
5.82 8.64e-03 GO:0043193 positive regulation of gene-specific transcription
4.75 8.67e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
29.07 8.78e-03 GO:0010718 positive regulation of epithelial to mesenchymal transition
3.27 9.60e-03 GO:0045893 positive regulation of transcription, DNA-dependent
6.55 9.61e-03 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
3.25 1.03e-02 GO:0009890 negative regulation of biosynthetic process
4.65 1.07e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.90 1.08e-02 GO:0032502 developmental process
3.38 1.11e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
3.22 1.18e-02 GO:0051254 positive regulation of RNA metabolic process
2.69 1.28e-02 GO:0009966 regulation of signal transduction
3.19 1.31e-02 GO:0044093 positive regulation of molecular function
2.10 1.40e-02 GO:0006355 regulation of transcription, DNA-dependent
8.81 1.42e-02 GO:0031346 positive regulation of cell projection organization
1.98 1.56e-02 GO:0031326 regulation of cellular biosynthetic process
2.58 1.63e-02 GO:0010604 positive regulation of macromolecule metabolic process
24.92 1.69e-02 GO:0010770 positive regulation of cell morphogenesis involved in differentiation
8.56 1.71e-02 GO:0051216 cartilage development
15.21 1.76e-02 GO:0050772 positive regulation of axonogenesis
3.59 1.85e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.98 1.92e-02 GO:0009888 tissue development
14.87 1.97e-02 GO:0060443 mammary gland morphogenesis
2.07 2.03e-02 GO:0048519 negative regulation of biological process
23.79 2.05e-02 GO:0045599 negative regulation of fat cell differentiation
5.95 2.06e-02 GO:0031344 regulation of cell projection organization
4.33 2.17e-02 GO:0048729 tissue morphogenesis
4.72 2.18e-02 GO:0045596 negative regulation of cell differentiation
49.05 2.28e-02 GO:0070208 protein heterotrimerization
8.18 2.31e-02 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
1.81 2.34e-02 GO:0080090 regulation of primary metabolic process
14.22 2.46e-02 GO:0061180 mammary gland epithelium development
2.73 2.54e-02 GO:0010646 regulation of cell communication
6.67 2.65e-02 GO:0045786 negative regulation of cell cycle
3.14 2.82e-02 GO:0031327 negative regulation of cellular biosynthetic process
2.42 3.01e-02 GO:0023051 regulation of signaling
7.77 3.23e-02 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.42 3.38e-02 GO:0050789 regulation of biological process
3.22 3.66e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.10 3.69e-02 GO:0071842 cellular component organization at cellular level
3.37 3.86e-02 GO:0045892 negative regulation of transcription, DNA-dependent
2.28 4.04e-02 GO:0006464 protein modification process
20.13 4.09e-02 GO:0010717 regulation of epithelial to mesenchymal transition
2.73 4.14e-02 GO:0010941 regulation of cell death
2.05 4.16e-02 GO:0071841 cellular component organization or biogenesis at cellular level
3.04 4.21e-02 GO:0048584 positive regulation of response to stimulus
4.39 4.23e-02 GO:0051301 cell division
3.17 4.39e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
3.32 4.59e-02 GO:0051253 negative regulation of RNA metabolic process
6.16 4.67e-02 GO:0010975 regulation of neuron projection development
7.33 4.68e-02 GO:0010638 positive regulation of organelle organization
39.24 4.83e-02 GO:0031100 organ regeneration
9.13 4.84e-02 GO:0050770 regulation of axonogenesis

Gene overrepresentation in compartment category:

enrichment p-value GO term description
1.86 3.21e-06 GO:0005634 nucleus
2.48 1.51e-04 GO:0044428 nuclear part
1.35 3.65e-04 GO:0005622 intracellular
1.35 5.24e-04 GO:0044424 intracellular part
2.56 6.63e-04 GO:0031981 nuclear lumen
2.38 1.12e-03 GO:0070013 intracellular organelle lumen
2.38 1.16e-03 GO:0043233 organelle lumen
2.33 1.70e-03 GO:0031974 membrane-enclosed lumen
2.85 1.74e-03 GO:0005654 nucleoplasm
1.39 2.10e-03 GO:0043226 organelle
1.42 3.45e-03 GO:0043231 intracellular membrane-bounded organelle
1.38 3.70e-03 GO:0043229 intracellular organelle
1.42 3.76e-03 GO:0043227 membrane-bounded organelle
1.89 7.80e-03 GO:0043234 protein complex
8.08 4.78e-02 GO:0016585 chromatin remodeling complex

Gene overrepresentation in function category:

enrichment p-value GO term description
1.87 8.72e-08 GO:0005515 protein binding
1.41 1.39e-05 GO:0005488 binding
2.84 6.72e-03 GO:0030528 transcription regulator activity
4.18 2.48e-02 GO:0016564 transcription repressor activity