• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: NFY{A,B,C}.p2

Z-value: 4.376

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Top targets:

Promoter	Score	Refseq	Gene	Description
chr11_-_98885428	28.477	NM_011623	Top2a	topoisomerase (DNA) II alpha
chr16_-_17125198	24.790	NM_183287	2610318N02Rik	RIKEN cDNA 2610318N02 gene
chr11_-_86922163	24.113	NM_175563	Prr11	proline rich 11
chr11_+_71855939	22.641	NM_144526	Fam64a	family with sequence similarity 64, member A
chr6_+_124780226	21.802		Cdca3	cell division cycle associated 3
chr11_-_97049143	19.306		Kpnb1	karyopherin (importin) beta 1
chr16_+_38089086	18.978	NM_019827	Gsk3b	glycogen synthase kinase 3 beta
chr1_-_191511950	18.761	NM_001081363	Cenpf	centromere protein F
chr4_+_124334876	18.280	NM_011141	Pou3f1	POU domain, class 3, transcription factor 1
chr13_+_23838602	17.768	NM_175664	Hist1h2bb	histone cluster 1, H2bb
chr1_+_42752608	17.183
chr1_+_141351340	16.803	NM_009791	Aspm	asp (abnormal spindle)-like, microcephaly associated (Drosophila)
chr13_+_21879356	16.645	NM_178202	Hist1h2bp	histone cluster 1, H2bp
chr3_+_32607582	16.629		Actl6a	actin-like 6A
chr13_+_22127689	16.043	NM_175665	Hist1h2bk	histone cluster 1, H2bk
chr9_+_44142772	15.750	NM_010436	H2afx	H2A histone family, member X
chr7_-_56892061	15.552	NM_001005232	Dbx1	developing brain homeobox 1
chr13_-_23837389	15.452	NM_175653	Hist1h3c	histone cluster 1, H3c
chr5_+_124889925	15.328	NM_030241	Setd8	SET domain containing (lysine methyltransferase) 8
chr6_+_124780193	14.496	NM_013538	Cdca3	cell division cycle associated 3
chr5_+_30969259	14.143	NM_007681	Cenpa	centromere protein A
chr3_-_27052733	13.587	NM_001177625 NM_007900	Ect2	ect2 oncogene
chr1_+_193645351	13.540	NM_010892	Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2
chr11_-_97049185	13.486	NM_008379	Kpnb1	karyopherin (importin) beta 1
chr4_-_118109775	13.238	NM_023223	Cdc20	cell division cycle 20 homolog (S. cerevisiae)
chr2_-_172195998	13.127	NM_011497	Aurka	aurora kinase A
chr6_-_82724366	12.980	NM_013820	Hk2	hexokinase 2
chrX_+_97972559	12.968	NM_001177780	Dlg3	discs, large homolog 3 (Drosophila)
chr13_+_23666249	12.773	NM_178188	Hist1h2ad Hist1h2ai	histone cluster 1, H2ad histone cluster 1, H2ai
chr4_-_41411865	12.396	NM_024241	Kif24	kinesin family member 24
chr6_-_83071206	12.340		Wbp1	WW domain binding protein 1
chr13_-_23666058	12.274	NM_178195	Hist1h2bf	histone cluster 1, H2bf
chr13_-_22127419	12.203	NM_175659	Hist1h2ah	histone cluster 1, H2ah
chr16_+_14163414	12.144		Nde1	nuclear distribution gene E homolog 1 (A nidulans)
chr11_+_68859125	12.023	NM_011496	Aurkb	aurora kinase B
chr13_+_75844950	12.012		Ell2	elongation factor RNA polymerase II 2
chr14_-_48037815	12.000		Dlgap5	discs, large (Drosophila) homolog-associated protein 5
chr10_-_80813067	11.754	NM_001163165 NM_010440	Hmg20b	high mobility group 20 B
chr3_+_96073622	11.729	NM_175666	Hist2h2bb	histone cluster 2, H2bb
chr11_-_40546863	11.625	NM_013552	Hmmr	hyaluronan mediated motility receptor (RHAMM)
chr13_-_56353523	11.617	NM_010896	Neurog1	neurogenin 1
chr16_+_52031733	11.548		Cblb	Casitas B-lineage lymphoma b
chr9_-_70269246	11.544		Ccnb2	cyclin B2
chr7_+_86805081	11.432	NM_029835	5730590G19Rik	RIKEN cDNA 5730590G19 gene
chr8_+_109127245	11.102	NM_009864	Cdh1	cadherin 1
chr8_+_86479405	11.082	NM_024184	Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr17_-_34137221	10.944	NM_001001892	H2-K1	histocompatibility 2, K1, K region
chr2_+_25227840	10.915	NM_001081085	2010317E24Rik	RIKEN cDNA 2010317E24 gene
chr13_+_51740600	10.853	NM_025415	Cks2	CDC28 protein kinase regulatory subunit 2
chr16_+_52031704	10.830		Cblb	Casitas B-lineage lymphoma b
chr4_+_132324212	10.727	NM_011284	Rpa2	replication protein A2
chr7_-_150646883	10.695	NM_001161624 NM_009876	Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)
chr3_-_89222140	10.514	NM_016904	Cks1b	CDC28 protein kinase 1b
chr15_+_98905403	10.432	NM_001162506 NM_030159	Troap	trophinin associated protein
chr10_-_128258639	10.426	NM_024180	Ormdl2	ORM1-like 2 (S. cerevisiae)
chr18_-_33373428	10.217	NM_133774	Stard4	StAR-related lipid transfer (START) domain containing 4
chr13_+_23627286	10.130	NM_145073	Hist1h3g	histone cluster 1, H3g
chr11_+_40547143	10.050	NM_026023	Nudcd2	NudC domain containing 2
chr5_-_38215607	10.035	NM_010835	Msx1	homeobox, msh-like 1
chr1_+_136859153	10.025	NM_026024	Ube2t	ubiquitin-conjugating enzyme E2T (putative)
chr10_+_79317409	9.967		Ptbp1	polypyrimidine tract binding protein 1
chr4_-_135429715	9.918		Pnrc2	proline-rich nuclear receptor coactivator 2
chr4_-_43013217	9.825	NM_009503	Vcp	valosin containing protein
chr19_-_7114388	9.750	NM_016737	Stip1	stress-induced phosphoprotein 1
chr11_+_94797565	9.541	NM_007742	Col1a1	collagen, type I, alpha 1
chr10_-_79862025	9.397		Mbd3	methyl-CpG binding domain protein 3
chr6_+_88148657	9.357	NM_008090	Gata2	GATA binding protein 2
chr16_+_14163356	9.238	NM_001114085 NM_023317	Nde1	nuclear distribution gene E homolog 1 (A nidulans)
chr11_-_97048933	9.163		Kpnb1	karyopherin (importin) beta 1
chr8_-_125842456	9.008	NM_016925	Fanca	Fanconi anemia, complementation group A
chr6_-_125141525	8.991	NM_146171	Ncapd2	non-SMC condensin I complex, subunit D2
chr9_+_83728295	8.917	NM_001110265 NM_009445	Ttk	Ttk protein kinase
chr3_+_121129396	8.869	NM_028044	Cnn3	calponin 3, acidic
chr6_+_4455686	8.737	NM_007743	Col1a2	collagen, type I, alpha 2
chr14_+_47380287	8.716		Cdkn3	cyclin-dependent kinase inhibitor 3
chr3_-_96024766	8.714	NM_175662	Hist2h2ac	histone cluster 2, H2ac
chr13_-_23854226	8.693	NM_013550	Hist1h3a	histone cluster 1, H3a
chr10_-_68815606	8.662	NM_007659	Cdk1	cyclin-dependent kinase 1
chr15_-_82074765	8.613	NM_001080158	Cenpm	centromere protein M
chr5_+_90889913	8.571	NM_009654	Alb	albumin
chr17_+_56443766	8.476		Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1
chr7_+_138703898	8.454	NM_009774	Bub3	budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae)
chr13_-_53568111	8.442	NM_013601	Msx2	homeobox, msh-like 2
chr11_+_54716354	8.436	NM_001083929 NM_008161	Gpx3	glutathione peroxidase 3
chr14_-_66452720	8.424	NM_028039	Esco2	establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr8_+_59990639	8.407	NM_008252	Hmgb2	high mobility group box 2
chr2_+_181498036	8.338	NM_001171615	Myt1	myelin transcription factor 1
chr1_-_78193381	8.328	NM_001159520 NM_008781	Pax3	paired box gene 3
chr4_-_135429739	8.144		Pnrc2	proline-rich nuclear receptor coactivator 2
chr2_-_132078887	8.078	NM_011045	Pcna	proliferating cell nuclear antigen
chr14_+_47380215	8.077	NM_028222	Cdkn3	cyclin-dependent kinase inhibitor 3
chr18_+_56591785	8.012	NM_026240	Gramd3	GRAM domain containing 3
chr8_+_86176531	7.998	NM_018771	Gipc1	GIPC PDZ domain containing family, member 1
chr8_+_24521967	7.955	NM_013834	Sfrp1	secreted frizzled-related protein 1
chr16_-_15637390	7.950	NM_008565	Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chr19_-_60302398	7.928		D19Ertd737e	DNA segment, Chr 19, ERATO Doi 737, expressed
chr13_+_109106530	7.898	NM_178683	Depdc1b	DEP domain containing 1B
chr18_+_34784589	7.871	NM_009004 NM_001166406	Kif20a	kinesin family member 20A
chr14_-_48037874	7.794		Dlgap5	discs, large (Drosophila) homolog-associated protein 5
chr1_-_171899278	7.754		Hsd17b7	hydroxysteroid (17-beta) dehydrogenase 7
chr13_-_23635220	7.697	NM_178197	Hist1h2bh	histone cluster 1, H2bh
chr18_-_34911152	7.611	NM_009860	Cdc25c	cell division cycle 25 homolog C (S. pombe)
chrX_-_7651846	7.543	NM_011514	Suv39h1	suppressor of variegation 3-9 homolog 1 (Drosophila)
chr9_-_70269326	7.477	NM_007630	Ccnb2	cyclin B2
chr3_+_108087046	7.448	NM_019972	Sort1	sortilin 1
chr7_-_146768633	7.438	NM_183248	Nkx6-2	NK6 homeobox 2
chrX_+_108009728	7.420	NM_008901	Pou3f4	POU domain, class 3, transcription factor 4
chr13_+_21809496	7.413	NM_178206	Hist1h3h	histone cluster 1, H3h
chr2_+_164595415	7.404	NM_026785	Ube2c	ubiquitin-conjugating enzyme E2C
chr10_+_75495391	7.337		Zfp280b	zinc finger protein 280B
chr14_-_68333666	7.295	NM_001110162	Cdca2	cell division cycle associated 2
chr4_+_114672722	7.290	NM_009185	Stil	Scl/Tal1 interrupting locus
chr13_-_21872421	7.280	NM_020034	Hist1h1b	histone cluster 1, H1b
chr15_-_83555335	7.277	NM_022723	Scube1	signal peptide, CUB domain, EGF-like 1
chr4_+_154335029	7.172	NM_010419	Hes5	hairy and enhancer of split 5 (Drosophila)
chrX_-_49967112	7.079	NM_016697	Gpc3	glypican 3
chr8_-_67212325	7.044	NM_025436	Sc4mol	sterol-C4-methyl oxidase-like
chr4_-_22415277	7.006	NM_008899	Pou3f2	POU domain, class 3, transcription factor 2
chr19_-_12869863	6.990		Zfp91	zinc finger protein 91
chr3_+_108087057	6.957		Sort1	sortilin 1
chr11_-_6344354	6.854		H2afv	H2A histone family, member V
chr10_+_79317316	6.832	NM_001077363 NM_008956	Ptbp1	polypyrimidine tract binding protein 1
chr15_-_82075137	6.741	NM_025639 NM_178269	Cenpm	centromere protein M
chr11_+_87405628	6.720	NM_133215	Mtmr4	myotubularin related protein 4
chr19_+_37450854	6.676	NM_010615	Kif11	kinesin family member 11
chr3_-_36470904	6.546	NM_009828	Ccna2	cyclin A2
chr13_-_3917356	6.539	NM_019671	Net1	neuroepithelial cell transforming gene 1
chr11_-_120434075	6.508		P4hb	prolyl 4-hydroxylase, beta polypeptide
chr2_+_91366966	6.505		Ckap5	cytoskeleton associated protein 5
chr9_-_21564723	6.494	NM_026282	Spc24	SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr7_-_137409721	6.433		Fgfr2	fibroblast growth factor receptor 2
chr7_+_117205194	6.394	NM_009281	Zfp143	zinc finger protein 143
chr11_+_86922732	6.287	NM_025377	Fam33a	family with sequence similarity 33, member A
chr5_+_103854200	6.278	NM_011204	Ptpn13	protein tyrosine phosphatase, non-receptor type 13
chr4_-_22415444	6.275		Pou3f2	POU domain, class 3, transcription factor 2
chr13_-_23775827	6.269	NM_178189	Hist1h2ac	histone cluster 1, H2ac
chr17_+_7374435	6.215	NM_011299	Rps6ka2	ribosomal protein S6 kinase, polypeptide 2
chr1_-_93309713	6.205	NM_019479	Hes6	hairy and enhancer of split 6 (Drosophila)
chr2_-_127657532	6.150	NM_001113179 NM_009772	Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
chr11_+_116295502	6.141		Fam100b	family with sequence similarity 100, member B
chr5_+_34001199	6.129		Tacc3	transforming, acidic coiled-coil containing protein 3
chr2_+_131012677	6.119	NM_001111075 NM_023117	Cdc25b	cell division cycle 25 homolog B (S. pombe)
chr10_-_128142007	6.101	NM_016756 NM_183417	Cdk2	cyclin-dependent kinase 2
chr8_-_4325051	6.100	NM_010485	Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
chr11_-_120434181	6.067		P4hb	prolyl 4-hydroxylase, beta polypeptide
chr4_-_124614072	6.056	NM_026560	Cdca8	cell division cycle associated 8
chr2_-_154395469	6.055	NM_007891	E2f1	E2F transcription factor 1
chr2_+_164595389	6.051		Ube2c	ubiquitin-conjugating enzyme E2C
chr6_-_87800966	6.041	NM_001109745 NM_001109746 NM_013493	Cnbp	cellular nucleic acid binding protein
chr9_-_107537602	6.028	NM_008138	Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr2_-_129122892	6.017	NM_181589	Ckap2l	cytoskeleton associated protein 2-like
chr9_-_61794540	6.017	NM_024245	Kif23	kinesin family member 23
chr2_+_152673699	5.955	NM_001141975 NM_001141976 NM_001141977 NM_001141978 NM_028109	Tpx2	TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr3_-_68848588	5.943		Trim59	tripartite motif-containing 59
chr15_-_78004452	5.939	NM_025931	Ift27	intraflagellar transport 27 homolog (Chlamydomonas)
chr16_+_37539964	5.920	NM_001042499	Rabl3	RAB, member of RAS oncogene family-like 3
chr6_+_29644178	5.851	NM_146173	Tspan33	tetraspanin 33
chr11_-_97490978	5.803	NM_175332	E130012A19Rik	RIKEN cDNA E130012A19 gene
chr1_-_135975681	5.799	NM_007570	Btg2	B-cell translocation gene 2, anti-proliferative
chr3_-_36470882	5.796		Ccna2	cyclin A2
chr6_-_47763309	5.796		Pdia4	protein disulfide isomerase associated 4
chr2_+_119444452	5.764		Nusap1	nucleolar and spindle associated protein 1
chr8_+_73118329	5.730	NM_023627	Isyna1	myo-inositol 1-phosphate synthase A1
chr10_+_79451369	5.684		Cnn2	calponin 2
chr2_+_164595447	5.669		Ube2c	ubiquitin-conjugating enzyme E2C
chr12_+_78339071	5.655		Fut8	fucosyltransferase 8
chr13_+_51942043	5.629	NM_011817	Gadd45g	growth arrest and DNA-damage-inducible 45 gamma
chr4_+_47366162	5.609	NM_009370	Tgfbr1	transforming growth factor, beta receptor I
chr11_+_102465839	5.608		Fzd2	frizzled homolog 2 (Drosophila)
chr3_-_36470845	5.608		Ccna2	cyclin A2
chr13_+_23646900	5.575	NM_145713	Hist1h1d	histone cluster 1, H1d
chr17_-_25097542	5.529	NM_198937	Hn1l	hematological and neurological expressed 1-like
chr14_+_20570444	5.515	NM_008695	Nid2	nidogen 2
chr13_-_105018845	5.497	NM_172807	Ppwd1	peptidylprolyl isomerase domain and WD repeat containing 1
chr1_+_58052814	5.493	NM_199007	Sgol2	shugoshin-like 2 (S. pombe)
chr13_+_23842956	5.493	NM_175660	Hist1h2ab	histone cluster 1, H2ab
chr15_-_99481964	5.489	NM_012025	Racgap1	Rac GTPase-activating protein 1
chr3_+_95733186	5.481		Anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr2_+_167363696	5.464	NM_011427	Snai1	snail homolog 1 (Drosophila)
chr2_-_143836838	5.459	NM_024281 NM_133626	Rrbp1	ribosome binding protein 1
chr13_-_23790310	5.446	NM_178208	Hist1h4c	histone cluster 1, H4c
chr2_-_168592528	5.436	NM_175303 NM_201395 NM_201396	Sall4	sal-like 4 (Drosophila)
chr9_-_111174027	5.436		Mlh1	mutL homolog 1 (E. coli)
chr3_+_133899454	5.428		Cxxc4	CXXC finger 4
chr17_+_56443710	5.405	NM_001111078 NM_001111080	Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1
chr2_+_152561983	5.402	NM_010495	Id1	inhibitor of DNA binding 1
chrX_+_97821403	5.401	NM_008446	Kif4	kinesin family member 4
chr12_-_101121613	5.393	NM_030172	2610021K21Rik	RIKEN cDNA 2610021K21 gene
chr11_+_102465684	5.383	NM_020510	Fzd2	frizzled homolog 2 (Drosophila)
chrX_-_99352341	5.372	NM_146235	Ercc6l	excision repair cross-complementing rodent repair deficiency complementation group 6 - like
chr11_-_68787314	5.369	NM_001101644 NM_021329	Gm4535 Rangrf	predicted gene 4535 RAN guanine nucleotide release factor
chr11_-_96777696	5.341	NM_030248	Cdk5rap3	CDK5 regulatory subunit associated protein 3
chr9_+_37015872	5.337	NM_025464	Tmem218	transmembrane protein 218
chr11_-_102786403	5.329		Kif18b	kinesin family member 18B
chr11_-_106021399	5.315	NM_172397	Limd2	LIM domain containing 2
chr2_+_91105271	5.307	NM_001166024 NM_023854	Arfgap2	ADP-ribosylation factor GTPase activating protein 2
chr1_-_171899306	5.306	NM_010476	Hsd17b7	hydroxysteroid (17-beta) dehydrogenase 7
chr6_+_128313041	5.306		Foxm1	forkhead box M1
chr7_+_129302998	5.306		Plk1	polo-like kinase 1 (Drosophila)
chr8_+_32222291	5.271	NM_175136	Rnf122	ring finger protein 122

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
3.68	9.82e-39	GO:0007049	cell cycle
3.93	6.10e-32	GO:0022402	cell cycle process
1.60	7.69e-31	GO:0044237	cellular metabolic process
4.38	9.70e-30	GO:0022403	cell cycle phase
4.86	2.09e-29	GO:0000279	M phase
1.73	1.75e-28	GO:0044260	cellular macromolecule metabolic process
1.88	1.13e-27	GO:0034641	cellular nitrogen compound metabolic process
4.73	2.29e-27	GO:0051301	cell division
2.04	3.80e-27	GO:0090304	nucleic acid metabolic process
1.56	4.35e-27	GO:0044238	primary metabolic process
1.92	1.39e-26	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49	2.12e-26	GO:0008152	metabolic process
1.84	2.48e-26	GO:0006807	nitrogen compound metabolic process
1.64	2.83e-25	GO:0043170	macromolecule metabolic process
5.47	9.79e-25	GO:0000087	M phase of mitotic cell cycle
1.88	4.96e-24	GO:0009058	biosynthetic process
5.40	1.48e-23	GO:0000280	nuclear division
5.40	1.48e-23	GO:0007067	mitosis
4.11	7.54e-23	GO:0000278	mitotic cell cycle
5.19	1.44e-22	GO:0048285	organelle fission
1.86	2.14e-22	GO:0044249	cellular biosynthetic process
2.40	3.07e-22	GO:0006996	organelle organization
2.00	3.80e-20	GO:0071841	cellular component organization or biogenesis at cellular level
2.02	1.83e-19	GO:0071842	cellular component organization at cellular level
1.79	6.02e-18	GO:0071840	cellular component organization or biogenesis
1.89	1.16e-17	GO:0009059	macromolecule biosynthetic process
1.89	2.15e-17	GO:0034645	cellular macromolecule biosynthetic process
1.80	3.80e-17	GO:0016043	cellular component organization
1.69	2.38e-16	GO:0060255	regulation of macromolecule metabolic process
3.24	2.47e-16	GO:0006259	DNA metabolic process
1.24	3.05e-16	GO:0009987	cellular process
1.62	3.61e-16	GO:0019222	regulation of metabolic process
1.66	1.71e-15	GO:0080090	regulation of primary metabolic process
1.65	2.32e-15	GO:0031323	regulation of cellular metabolic process
1.78	2.46e-15	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.15	2.55e-15	GO:0051276	chromosome organization
1.84	7.14e-15	GO:0016070	RNA metabolic process
1.76	8.60e-15	GO:0051171	regulation of nitrogen compound metabolic process
1.83	2.19e-14	GO:0006355	regulation of transcription, DNA-dependent
1.78	2.37e-14	GO:0010467	gene expression
1.78	3.06e-14	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.81	4.10e-14	GO:0051252	regulation of RNA metabolic process
1.75	5.30e-14	GO:0010468	regulation of gene expression
2.73	7.62e-14	GO:0033554	cellular response to stress
1.76	1.13e-13	GO:0010556	regulation of macromolecule biosynthetic process
5.99	1.66e-13	GO:0071103	DNA conformation change
3.26	3.10e-13	GO:0006974	response to DNA damage stimulus
1.69	3.29e-12	GO:0009889	regulation of biosynthetic process
1.68	6.36e-12	GO:0031326	regulation of cellular biosynthetic process
1.88	2.45e-11	GO:0032774	RNA biosynthetic process
4.64	3.48e-11	GO:0006260	DNA replication
1.87	4.54e-11	GO:0006351	transcription, DNA-dependent
6.10	8.27e-11	GO:0006323	DNA packaging
3.45	1.03e-10	GO:0006281	DNA repair
5.30	1.18e-09	GO:0007059	chromosome segregation
2.96	2.97e-09	GO:0006325	chromatin organization
2.72	5.33e-09	GO:0051726	regulation of cell cycle
6.69	1.07e-08	GO:0071824	protein-DNA complex subunit organization
3.59	1.31e-08	GO:0010564	regulation of cell cycle process
6.92	1.84e-08	GO:0031497	chromatin assembly
7.35	2.05e-08	GO:0006334	nucleosome assembly
6.48	2.11e-08	GO:0006333	chromatin assembly or disassembly
6.80	2.63e-08	GO:0034728	nucleosome organization
1.67	2.95e-08	GO:0048523	negative regulation of cellular process
6.68	3.73e-08	GO:0065004	protein-DNA complex assembly
4.60	1.32e-06	GO:0071156	regulation of cell cycle arrest
4.56	1.62e-06	GO:0006310	DNA recombination
4.51	1.99e-06	GO:0007126	meiosis
4.51	1.99e-06	GO:0051327	M phase of meiotic cell cycle
4.47	2.43e-06	GO:0051321	meiotic cell cycle
8.29	2.80e-06	GO:0016126	sterol biosynthetic process
4.71	4.69e-06	GO:0000075	cell cycle checkpoint
1.48	6.88e-06	GO:0007275	multicellular organismal development
1.54	1.04e-05	GO:0048519	negative regulation of biological process
1.65	1.09e-05	GO:0048513	organ development
2.01	1.19e-05	GO:0009790	embryo development
1.91	1.20e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.53	1.45e-05	GO:0048731	system development
1.44	2.02e-05	GO:0032502	developmental process
6.00	2.72e-05	GO:0031570	DNA integrity checkpoint
1.55	2.94e-05	GO:0044267	cellular protein metabolic process
2.07	3.02e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
8.63	3.21e-05	GO:0006695	cholesterol biosynthetic process
2.07	3.86e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.48	5.05e-05	GO:0048856	anatomical structure development
2.10	6.70e-05	GO:0043933	macromolecular complex subunit organization
6.08	6.97e-05	GO:0000077	DNA damage checkpoint
1.49	7.60e-05	GO:0048522	positive regulation of cellular process
1.85	7.86e-05	GO:0031324	negative regulation of cellular metabolic process
2.61	9.50e-05	GO:0034621	cellular macromolecular complex subunit organization
2.31	1.44e-04	GO:0007417	central nervous system development
1.71	1.55e-04	GO:0010604	positive regulation of macromolecule metabolic process
14.28	1.55e-04	GO:0006270	DNA-dependent DNA replication initiation
8.50	1.77e-04	GO:0031576	G2/M transition checkpoint
1.78	1.99e-04	GO:0009892	negative regulation of metabolic process
1.89	2.58e-04	GO:0010628	positive regulation of gene expression
1.43	3.61e-04	GO:0048518	positive regulation of biological process
5.77	4.32e-04	GO:0006261	DNA-dependent DNA replication
2.06	5.90e-04	GO:0065003	macromolecular complex assembly
1.63	7.26e-04	GO:0009893	positive regulation of metabolic process
1.78	7.66e-04	GO:0010605	negative regulation of macromolecule metabolic process
2.57	9.94e-04	GO:0034622	cellular macromolecular complex assembly
1.88	1.04e-03	GO:0009890	negative regulation of biosynthetic process
1.57	1.11e-03	GO:0044281	small molecule metabolic process
2.10	1.30e-03	GO:0009792	embryo development ending in birth or egg hatching
1.90	1.30e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.42	1.38e-03	GO:0019538	protein metabolic process
1.92	1.47e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.87	1.47e-03	GO:0051254	positive regulation of RNA metabolic process
6.24	1.59e-03	GO:0000819	sister chromatid segregation
1.80	1.82e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.87	1.95e-03	GO:0031327	negative regulation of cellular biosynthetic process
2.09	1.98e-03	GO:0043009	chordate embryonic development
1.97	2.01e-03	GO:0051253	negative regulation of RNA metabolic process
1.56	2.01e-03	GO:0006950	response to stress
3.99	2.02e-03	GO:0016125	sterol metabolic process
2.35	2.08e-03	GO:0007420	brain development
2.98	2.14e-03	GO:0045165	cell fate commitment
1.74	2.18e-03	GO:0044085	cellular component biogenesis
1.63	2.32e-03	GO:0031325	positive regulation of cellular metabolic process
4.13	2.54e-03	GO:0006694	steroid biosynthetic process
1.96	2.69e-03	GO:0045892	negative regulation of transcription, DNA-dependent
2.62	3.20e-03	GO:0007017	microtubule-based process
1.66	3.29e-03	GO:0007399	nervous system development
8.59	3.34e-03	GO:0031572	G2/M transition DNA damage checkpoint
1.84	3.65e-03	GO:0045893	positive regulation of transcription, DNA-dependent
5.21	4.23e-03	GO:0000910	cytokinesis
1.76	4.57e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
2.02	5.09e-03	GO:0072358	cardiovascular system development
2.02	5.09e-03	GO:0072359	circulatory system development
6.18	5.57e-03	GO:0000070	mitotic sister chromatid segregation
2.30	6.41e-03	GO:0016568	chromatin modification
1.62	8.88e-03	GO:0050790	regulation of catalytic activity
2.40	9.42e-03	GO:0007507	heart development
6.33	1.43e-02	GO:0001837	epithelial to mesenchymal transition
3.83	1.50e-02	GO:0008203	cholesterol metabolic process
1.72	1.61e-02	GO:0022607	cellular component assembly
2.88	1.71e-02	GO:0000226	microtubule cytoskeleton organization
2.04	1.72e-02	GO:0007010	cytoskeleton organization
1.66	1.74e-02	GO:0051641	cellular localization
2.05	1.94e-02	GO:0048598	embryonic morphogenesis
2.64	1.96e-02	GO:0033365	protein localization to organelle
1.86	2.10e-02	GO:0009887	organ morphogenesis
1.73	2.11e-02	GO:0022008	neurogenesis
1.48	2.24e-02	GO:0043412	macromolecule modification
3.37	2.24e-02	GO:0051325	interphase
4.15	2.46e-02	GO:0006302	double-strand break repair
4.45	2.47e-02	GO:0048663	neuron fate commitment
3.47	2.72e-02	GO:0034504	protein localization to nucleus
1.49	2.73e-02	GO:0006464	protein modification process
1.80	3.02e-02	GO:0010629	negative regulation of gene expression
2.45	3.62e-02	GO:0035239	tube morphogenesis
2.18	3.82e-02	GO:0008283	cell proliferation
1.68	4.00e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
2.05	4.24e-02	GO:0060284	regulation of cell development
2.30	4.26e-02	GO:0008380	RNA splicing
5.57	4.62e-02	GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis
2.46	4.89e-02	GO:0030900	forebrain development
3.90	4.90e-02	GO:0010212	response to ionizing radiation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.51	1.57e-62	GO:0044424	intracellular part
1.50	2.50e-62	GO:0005622	intracellular
2.01	1.50e-60	GO:0005634	nucleus
1.65	2.93e-57	GO:0043231	intracellular membrane-bounded organelle
1.64	7.00e-57	GO:0043227	membrane-bounded organelle
1.57	7.22e-55	GO:0043229	intracellular organelle
1.56	2.62e-54	GO:0043226	organelle
1.91	1.11e-37	GO:0044446	intracellular organelle part
1.89	5.69e-37	GO:0044422	organelle part
2.39	1.29e-29	GO:0044428	nuclear part
2.37	1.51e-27	GO:0031974	membrane-enclosed lumen
2.38	2.14e-27	GO:0070013	intracellular organelle lumen
2.38	2.72e-27	GO:0043233	organelle lumen
2.49	6.31e-27	GO:0031981	nuclear lumen
4.00	9.13e-27	GO:0005694	chromosome
4.03	4.76e-25	GO:0044427	chromosomal part
2.70	6.82e-23	GO:0005654	nucleoplasm
1.77	9.17e-21	GO:0032991	macromolecular complex
1.38	3.95e-19	GO:0005737	cytoplasm
1.87	9.05e-18	GO:0043228	non-membrane-bounded organelle
1.87	9.05e-18	GO:0043232	intracellular non-membrane-bounded organelle
1.16	7.78e-16	GO:0005623	cell
1.16	7.78e-16	GO:0044464	cell part
1.73	6.01e-15	GO:0043234	protein complex
5.92	1.06e-12	GO:0000793	condensed chromosome
2.73	1.07e-12	GO:0015630	microtubule cytoskeleton
4.84	2.11e-11	GO:0000775	chromosome, centromeric region
3.69	8.45e-10	GO:0000785	chromatin
3.65	2.40e-09	GO:0000228	nuclear chromosome
6.36	1.60e-08	GO:0000794	condensed nuclear chromosome
3.72	1.90e-08	GO:0044454	nuclear chromosome part
6.94	3.51e-08	GO:0030496	midbody
4.51	5.80e-08	GO:0005819	spindle
1.34	7.09e-08	GO:0044444	cytoplasmic part
5.23	2.43e-07	GO:0032993	protein-DNA complex
4.98	2.43e-07	GO:0000776	kinetochore
6.66	2.49e-07	GO:0000786	nucleosome
1.67	1.28e-05	GO:0005829	cytosol
3.06	1.58e-05	GO:0005813	centrosome
7.48	2.99e-05	GO:0000779	condensed chromosome, centromeric region
1.63	7.45e-05	GO:0005856	cytoskeleton
2.77	1.48e-04	GO:0005815	microtubule organizing center
1.94	1.53e-04	GO:0044451	nucleoplasm part
10.99	3.08e-04	GO:0000780	condensed nuclear chromosome, centromeric region
1.76	3.09e-04	GO:0044430	cytoskeletal part
2.36	8.16e-04	GO:0044432	endoplasmic reticulum part
2.38	1.87e-03	GO:0042175	nuclear membrane-endoplasmic reticulum network
2.41	2.01e-03	GO:0005789	endoplasmic reticulum membrane
2.32	5.81e-03	GO:0005874	microtubule
7.52	6.97e-03	GO:0045120	pronucleus
5.57	7.30e-03	GO:0005793	ER-Golgi intermediate compartment
4.98	7.46e-03	GO:0000922	spindle pole
16.32	9.65e-03	GO:0042555	MCM complex
11.34	1.05e-02	GO:0035098	ESC/E(Z) complex
1.68	1.30e-02	GO:0012505	endomembrane system
5.10	4.15e-02	GO:0008287	protein serine/threonine phosphatase complex
3.74	4.87e-02	GO:0034399	nuclear periphery

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.31	6.69e-22	GO:0005488	binding
1.92	3.25e-21	GO:0003676	nucleic acid binding
2.13	3.74e-20	GO:0003677	DNA binding
1.34	2.77e-08	GO:0005515	protein binding
1.62	9.76e-08	GO:0000166	nucleotide binding
3.32	5.92e-07	GO:0003682	chromatin binding
1.33	1.63e-06	GO:0003824	catalytic activity
1.93	3.13e-06	GO:0030528	transcription regulator activity
1.68	1.71e-05	GO:0005524	ATP binding
1.66	2.41e-05	GO:0032559	adenyl ribonucleotide binding
1.65	3.14e-05	GO:0030554	adenyl nucleotide binding
1.57	6.92e-05	GO:0035639	purine ribonucleoside triphosphate binding
2.97	6.98e-05	GO:0043566	structure-specific DNA binding
1.55	1.23e-04	GO:0032555	purine ribonucleotide binding
1.55	1.27e-04	GO:0032553	ribonucleotide binding
1.55	1.54e-04	GO:0017076	purine nucleotide binding
1.84	1.29e-03	GO:0003723	RNA binding
1.91	1.44e-03	GO:0017111	nucleoside-triphosphatase activity
9.52	1.47e-03	GO:0000217	DNA secondary structure binding
4.90	1.88e-03	GO:0003697	single-stranded DNA binding
1.81	6.11e-03	GO:0016462	pyrophosphatase activity
1.81	7.01e-03	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.80	7.34e-03	GO:0016817	hydrolase activity, acting on acid anhydrides
3.01	1.33e-02	GO:0016853	isomerase activity
11.34	1.46e-02	GO:0030983	mismatched DNA binding
3.54	3.17e-02	GO:0042393	histone binding
1.67	3.28e-02	GO:0001071	nucleic acid binding transcription factor activity
1.67	3.28e-02	GO:0003700	sequence-specific DNA binding transcription factor activity
2.63	3.51e-02	GO:0004721	phosphoprotein phosphatase activity
13.60	3.88e-02	GO:0000400	four-way junction DNA binding
1.61	4.93e-02	GO:0019899	enzyme binding