Motif ID: NHLH1,2.p2

Z-value: 1.954

Transcription factors associated with NHLH1,2.p2:

NameEntrezDescription
Nhlh1 18071 nescient helix loop helix 1
Nhlh2 18072 nescient helix loop helix 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Nhlh2chr3_+_101814059-0.601.1e-04Click!
Nhlh1chr1_-_173987681-0.411.2e-02Click!


Activity profile for motif NHLH1,2.p2.

activity profile for motif NHLH1,2.p2


Sorted Z-values histogram for motif NHLH1,2.p2

Sorted Z-values for motif NHLH1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NHLH1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr8_+_128519295 16.882 Kcnk1
potassium channel, subfamily K, member 1
chr7_+_53651811 16.651 NM_008421
NM_001112739
Kcnc1

potassium voltage gated channel, Shaw-related subfamily, member 1

chr7_+_129432585 15.309 NM_008855
Prkcb
protein kinase C, beta
chr8_+_128519001 14.928 NM_008430
Kcnk1
potassium channel, subfamily K, member 1
chr10_+_122115755 14.366 NM_001110218
NM_176919
Ppm1h

protein phosphatase 1H (PP2C domain containing)

chr8_-_89996474 14.138 NM_019626
Cbln1
cerebellin 1 precursor protein
chr9_+_69137694 13.443 Rora
RAR-related orphan receptor alpha
chr2_-_162486792 13.435 Ptprt
protein tyrosine phosphatase, receptor type, T
chr2_+_180332926 12.821 NM_009936
Col9a3
collagen, type IX, alpha 3
chr5_-_108978950 12.809 NM_007756
Cplx1
complexin 1
chr18_+_82723920 11.778 Mbp
myelin basic protein
chr2_+_156439426 11.566 NM_146128
Dlgap4
discs, large homolog-associated protein 4 (Drosophila)
chr7_+_129432810 11.246 Prkcb
protein kinase C, beta
chr4_-_133054355 10.883 NM_001081156
Trnp1
TMF1-regulated nuclear protein 1
chr10_-_6980199 10.826 NM_133485
Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr2_-_25174498 10.802 Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr1_-_166387998 10.752 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr8_-_113917651 10.451 NM_178086
Fa2h
fatty acid 2-hydroxylase
chr2_-_25174662 10.063 NM_001177656
NM_001177657
NM_008169
Grin1


glutamate receptor, ionotropic, NMDA1 (zeta 1)


chr5_+_137506122 9.832 NM_001039385
Vgf
VGF nerve growth factor inducible
chr10_-_6979959 9.774 Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr2_+_25118144 9.139 Tprn
taperin
chr4_-_63707964 8.803 Tnc
tenascin C
chr10_+_122116066 8.533 Ppm1h
protein phosphatase 1H (PP2C domain containing)
chr2_+_146047656 8.501 NM_016889
Insm1
insulinoma-associated 1
chr19_+_23833310 8.469 NM_177034
Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
chr13_-_112599181 8.391 NM_011945
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr10_+_98377759 8.299 NM_026482
Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr10_+_78243239 8.196 NM_009200
Slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr5_-_34630913 7.868 NM_001015039
Zfyve28
zinc finger, FYVE domain containing 28
chr9_-_53823107 7.644 NM_177769
Elmod1
ELMO domain containing 1
chr1_-_84692750 7.368 NM_152915
Dner
delta/notch-like EGF-related receptor
chr14_-_103381744 7.304 NM_177715
Kctd12
potassium channel tetramerisation domain containing 12
chr19_-_59150001 7.230 4930506M07Rik
RIKEN cDNA 4930506M07 gene
chr4_-_139802683 7.193 NM_198610
Igsf21
immunoglobin superfamily, member 21
chr3_+_31048841 7.048 NM_008770
Cldn11
claudin 11
chrX_+_162676910 6.945 Gpm6b
glycoprotein m6b
chr4_+_129985957 6.905 NM_010174
Fabp3
fatty acid binding protein 3, muscle and heart
chrX_+_7496899 6.607 NM_013892
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr2_+_158201373 6.588 NM_175692
Snhg11
small nucleolar RNA host gene 11
chr8_-_112692071 6.584 NM_007586
Calb2
calbindin 2
chr12_+_101437735 6.487 NM_009790
Calm1
calmodulin 1
chr10_+_57351786 6.464 NM_001039051
NM_008863
Pkib

protein kinase inhibitor beta, cAMP dependent, testis specific

chr13_-_12199109 6.329 NM_023868
Ryr2
ryanodine receptor 2, cardiac
chrX_-_119510890 6.297 NM_138742
Nap1l3
nucleosome assembly protein 1-like 3
chr1_+_75502181 6.270 Obsl1
obscurin-like 1
chr10_+_99478457 6.153 NM_013598
Kitl
kit ligand
chr2_+_158492854 6.006 NM_001159662
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr4_+_97444494 5.975 Nfia
nuclear factor I/A
chr17_+_44215761 5.969 NM_032003
NM_001168620
Enpp5

ectonucleotide pyrophosphatase/phosphodiesterase 5

chr10_-_30522912 5.895 NM_172495
Ncoa7
nuclear receptor coactivator 7
chr2_-_170232008 5.850 Bcas1
breast carcinoma amplified sequence 1
chr14_+_122874598 5.797 NM_009574
Zic2
zinc finger protein of the cerebellum 2
chr7_-_134968017 5.754 NM_024414
Stx1b
syntaxin 1B
chr1_+_179372452 5.720 Zfp238
zinc finger protein 238
chr17_+_25854116 5.612 NM_022422
Gng13
guanine nucleotide binding protein (G protein), gamma 13
chr14_+_34736806 5.598 Gdf10
growth differentiation factor 10
chr14_+_35124004 5.589 Glud1
glutamate dehydrogenase 1
chr12_+_17697623 5.529 Hpcal1
hippocalcin-like 1
chr4_+_128560786 5.442 Trim62
tripartite motif-containing 62
chr8_-_89996089 5.432 Cbln1
cerebellin 1 precursor protein
chr4_+_53453302 5.351 Slc44a1
solute carrier family 44, member 1
chr17_-_26338106 5.303 Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr6_-_115201866 5.278 NM_080639
Timp4
tissue inhibitor of metalloproteinase 4
chr7_-_31911884 5.247 NM_011322
Scn1b
sodium channel, voltage-gated, type I, beta
chr2_-_156817751 5.241 NM_013865
NM_180956
Ndrg3

N-myc downstream regulated gene 3

chr14_-_55531726 5.233 NM_021551
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr2_+_118605431 5.231 NM_170593
Disp2
dispatched homolog 2 (Drosophila)
chr16_+_91270009 5.212 NM_016968
Olig1
oligodendrocyte transcription factor 1
chr4_+_130348406 5.162 NM_011520
Sdc3
syndecan 3
chr10_+_78243274 5.149 Slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr3_-_125641429 5.132 NM_011674
Ugt8a
UDP galactosyltransferase 8A
chr1_-_137584672 5.104 Nav1
neuron navigator 1
chr7_+_52419317 5.033 Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr10_-_80488111 5.019 NM_145217
Diras1
DIRAS family, GTP-binding RAS-like 1
chr7_+_134094045 5.012 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr7_-_13623543 5.011 NM_001168469
Ube2m
ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)
chr11_+_16652205 4.983 NM_007912
NM_207655
Egfr

epidermal growth factor receptor

chr4_+_155068450 4.945 B930041F14Rik
RIKEN cDNA B930041F14 gene
chr19_+_46836085 4.854 NM_001102471
NM_033569
Cnnm2

cyclin M2

chr19_+_47253484 4.853 Neurl1a
neuralized homolog 1A (Drosophila)
chr8_-_73011217 4.802 NM_182991
Tmem59l
transmembrane protein 59-like
chrX_-_20498021 4.744 NM_001110780
NM_013680
Syn1

synapsin I

chr10_-_108447894 4.722 Syt1
synaptotagmin I
chr15_+_81641869 4.699 Tef
thyrotroph embryonic factor
chr9_-_53822931 4.686 Elmod1
ELMO domain containing 1
chr10_-_108447996 4.685 Syt1
synaptotagmin I
chr17_+_55585011 4.636 NM_172829
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr5_-_46030523 4.625 NM_021416
Fam184b
family with sequence similarity 184, member B
chr9_-_75459125 4.601 NM_016711
Tmod2
tropomodulin 2
chr9_-_54349409 4.600 NM_172771
Dmxl2
Dmx-like 2
chr14_-_70689267 4.577 Ppp3cc
protein phosphatase 3, catalytic subunit, gamma isoform
chr14_-_26588341 4.522 NM_001101433
Zcchc24
zinc finger, CCHC domain containing 24
chr15_+_78744328 4.353 NM_020271
Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr10_+_128346900 4.331 NM_007653
Cd63
CD63 antigen
chr4_-_57003214 4.290 NM_001142965
6430704M03Rik
RIKEN cDNA 6430704M03 gene
chr3_+_145421621 4.234 NM_026993
Ddah1
dimethylarginine dimethylaminohydrolase 1
chr8_+_10153910 4.223 NM_001081397
Myo16
myosin XVI
chr10_-_79076744 4.217 NM_198614
NM_001168624
C2cd4c

C2 calcium-dependent domain containing 4C

chr6_-_115201846 4.197 Timp4
tissue inhibitor of metalloproteinase 4
chr14_+_34736772 4.172 NM_145741
Gdf10
growth differentiation factor 10
chr14_+_77556569 4.163 Enox1
ecto-NOX disulfide-thiol exchanger 1
chr11_-_4847968 4.129 NM_010904
Nefh
neurofilament, heavy polypeptide
chr5_+_118292144 4.112 Nos1
nitric oxide synthase 1, neuronal
chr11_-_6375845 4.102 NM_011221
Purb
purine rich element binding protein B
chr10_-_60294129 4.102 NM_029770
Unc5b
unc-5 homolog B (C. elegans)
chr4_-_128798481 4.051 NM_010471
Hpca
hippocalcin
chr11_+_50038815 4.047 NM_145926
Mgat4b
mannoside acetylglucosaminyltransferase 4, isoenzyme B
chr17_+_46390828 4.029 NM_001111142
Gm88
predicted gene 88
chr11_+_53333270 3.973 NM_033144
Sept8
septin 8
chr2_+_55289530 3.970 NM_008426
Kcnj3
potassium inwardly-rectifying channel, subfamily J, member 3
chr10_+_93977597 3.961 NM_172051
Tmcc3
transmembrane and coiled coil domains 3
chr13_+_55050729 3.945 NM_153131
Unc5a
unc-5 homolog A (C. elegans)
chr3_+_136333083 3.922 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr2_-_148701164 3.920 Cst3
cystatin C
chr3_+_14886253 3.906 NM_009801
Car2
carbonic anhydrase 2
chr1_-_84692352 3.893 Dner
delta/notch-like EGF-related receptor
chr7_+_138079669 3.887 NM_019564
Htra1
HtrA serine peptidase 1
chr4_+_155068604 3.847 B930041F14Rik
RIKEN cDNA B930041F14 gene
chr7_+_17529961 3.825 NM_001099636
Pnmal2
PNMA-like 2
chr8_-_125201971 3.795 NM_001109873
NM_177289
Cbfa2t3

core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)

chr12_-_73171976 3.794 NM_181752
Gpr135
G protein-coupled receptor 135
chr8_-_87461251 3.781 NM_019945
Mast1
microtubule associated serine/threonine kinase 1
chr4_+_129662110 3.777 Bai2
brain-specific angiogenesis inhibitor 2
chr17_+_88840048 3.776 NM_180974
Foxn2
forkhead box N2
chr11_-_30168153 3.760 Spnb2
spectrin beta 2
chr2_+_25284190 3.756 NM_007379
Abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr8_+_121918768 3.745 NM_019966
Mlycd
malonyl-CoA decarboxylase
chr11_-_120645428 3.744 NM_009053
Rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr18_+_82723907 3.738 Mbp
myelin basic protein
chr3_+_101180976 3.679 NM_207205
Igsf3
immunoglobulin superfamily, member 3
chr10_-_108448003 3.663 Syt1
synaptotagmin I
chr8_+_24521967 3.656 NM_013834
Sfrp1
secreted frizzled-related protein 1
chr6_-_37249957 3.612 NM_001081206
Dgki
diacylglycerol kinase, iota
chr18_+_33098914 3.600 Camk4
calcium/calmodulin-dependent protein kinase IV
chr11_+_101017197 3.582 NM_134028
Tubg2
tubulin, gamma 2
chr14_-_56519012 3.568 NM_001082975
Sdr39u1
short chain dehydrogenase/reductase family 39U, member 1
chr4_+_57447340 3.567 Palm2
paralemmin 2
chr11_+_6963421 3.498 NM_009622
Adcy1
adenylate cyclase 1
chr10_+_42221973 3.488 Snx3
sorting nexin 3
chr7_+_64845887 3.465 NM_001038701
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr16_-_85173978 3.459 App
amyloid beta (A4) precursor protein
chr14_-_70689083 3.448 NM_008915
Ppp3cc
protein phosphatase 3, catalytic subunit, gamma isoform
chr18_+_45719464 3.445 Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr17_-_27650285 3.444 Grm4
glutamate receptor, metabotropic 4
chr6_+_114081227 3.410 NM_172890
Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr19_-_47089605 3.407 NM_001164363
Nt5c2
5'-nucleotidase, cytosolic II
chr16_-_20621287 3.406 NM_028420
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chrX_+_20425667 3.368 NM_001159645
NM_009703
Araf

v-raf murine sarcoma 3611 viral oncogene homolog

chr17_+_43153516 3.366 Tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr11_+_103994160 3.358 NM_007762
Crhr1
corticotropin releasing hormone receptor 1
chr17_-_45823145 3.323 NM_198167
Tmem63b
transmembrane protein 63b
chr3_-_107698658 3.316 4933431E20Rik
RIKEN cDNA 4933431E20 gene
chr7_+_52419289 3.313 NM_182993
Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr9_-_70504934 3.297 NM_172772
Fam63b
family with sequence similarity 63, member B
chr17_+_44215851 3.270 Enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr12_+_17697684 3.265


chr1_-_166388431 3.255 NM_009721
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr3_-_36589048 3.252 NM_019510
Trpc3
transient receptor potential cation channel, subfamily C, member 3
chr4_+_155068566 3.252 NM_178699
B930041F14Rik
RIKEN cDNA B930041F14 gene
chr11_-_3813644 3.250 Slc35e4
solute carrier family 35, member E4
chr10_-_120913138 3.237 NM_138956
Rassf3
Ras association (RalGDS/AF-6) domain family member 3
chr2_+_144993587 3.220 Slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr5_+_36100547 3.211 Ablim2
actin-binding LIM protein 2
chr9_-_75459046 3.197 Tmod2
tropomodulin 2
chr2_+_164311755 3.191 NM_026797
Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr15_+_78744862 3.186 Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr8_+_89996675 3.175 Gm2694
predicted gene 2694
chr18_+_35000283 3.160 NM_144865
Reep2
receptor accessory protein 2
chr19_+_5637459 3.135 NM_009045
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr11_-_79317471 3.134 Omg
oligodendrocyte myelin glycoprotein
chr10_+_11063201 3.129 NM_010146
Epm2a
epilepsy, progressive myoclonic epilepsy, type 2 gene alpha
chr10_-_108447674 3.116 NM_009306
Syt1
synaptotagmin I
chr5_-_125342745 3.072 Ccdc92
coiled-coil domain containing 92
chr14_-_13655592 3.012 NM_001042617
NM_012061
Cadps

Ca2+-dependent secretion activator

chr10_+_3134318 3.009 Cnksr3
Cnksr family member 3
chr9_+_118387306 2.988 NM_001164789
NM_010136
Eomes

eomesodermin homolog (Xenopus laevis)

chr13_+_109906361 2.938 Pde4d
phosphodiesterase 4D, cAMP specific
chr11_+_77744280 2.932 NM_021286
Sez6
seizure related gene 6
chr15_+_79921725 2.922 NM_009303
NM_207708
Syngr1

synaptogyrin 1

chr8_+_47556353 2.850 NM_007981
Acsl1
acyl-CoA synthetase long-chain family member 1
chr3_+_138405156 2.847 NM_019571
Tspan5
tetraspanin 5
chr6_-_136824323 2.844 NM_008597
Mgp
matrix Gla protein
chr4_-_109149274 2.840 Rnf11
ring finger protein 11
chr11_-_119908236 2.839 NM_001198785
NM_007377
Aatk

apoptosis-associated tyrosine kinase

chrX_+_7215705 2.829 NM_009305
Syp
synaptophysin
chr9_-_75458954 2.822 Tmod2
tropomodulin 2
chr11_-_75609557 2.806 NM_007873
Doc2b
double C2, beta
chr8_-_87461220 2.806 Mast1
microtubule associated serine/threonine kinase 1
chr13_-_6647924 2.801 NM_019703
Pfkp
phosphofructokinase, platelet
chr17_-_25707599 2.798 NM_011447
Sox8
SRY-box containing gene 8
chr16_-_85173944 2.796 NM_001198823
NM_001198824
NM_001198825
NM_001198826
NM_007471
App




amyloid beta (A4) precursor protein




chr5_+_150214363 2.796 NM_027519
6330406I15Rik
RIKEN cDNA 6330406I15 gene
chr12_-_11443284 2.794 NM_012038
Vsnl1
visinin-like 1
chr12_-_87165448 2.792 NM_021446
0610007P14Rik
RIKEN cDNA 0610007P14 gene
chr2_-_130468507 2.780 NM_197945
Prosapip1
ProSAPiP1 protein
chr7_+_35971403 2.775 NM_017394
Slc7a10
solute carrier family 7 (cationic amino acid transporter, y+ system), member 10
chr1_-_169323901 2.748 NM_025569
Mgst3
microsomal glutathione S-transferase 3
chr6_+_115084919 2.746 NM_001111015
NM_013681
Syn2

synapsin II

chr17_-_90855291 2.739



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
1.90 1.13e-10 GO:0006810 transport
4.17 1.51e-10 GO:0019226 transmission of nerve impulse
4.17 1.51e-10 GO:0035637 multicellular organismal signaling
1.87 3.97e-10 GO:0051234 establishment of localization
4.57 4.86e-10 GO:0007268 synaptic transmission
1.70 5.78e-08 GO:0051179 localization
3.40 7.45e-08 GO:0007267 cell-cell signaling
7.07 8.94e-08 GO:0006836 neurotransmitter transport
2.83 9.09e-08 GO:0007154 cell communication
4.28 7.10e-06 GO:0050804 regulation of synaptic transmission
3.97 3.01e-05 GO:0051969 regulation of transmission of nerve impulse
1.96 3.10e-05 GO:0023051 regulation of signaling
8.93 3.72e-05 GO:0007269 neurotransmitter secretion
2.09 1.01e-04 GO:0010646 regulation of cell communication
3.65 1.42e-04 GO:0031644 regulation of neurological system process
2.32 1.71e-04 GO:0051049 regulation of transport
6.11 2.56e-04 GO:0001505 regulation of neurotransmitter levels
4.14 2.65e-04 GO:0060627 regulation of vesicle-mediated transport
2.06 3.50e-04 GO:0032879 regulation of localization
2.60 4.22e-04 GO:0030001 metal ion transport
6.40 4.53e-04 GO:0017157 regulation of exocytosis
4.00 4.67e-04 GO:0042391 regulation of membrane potential
4.92 5.64e-04 GO:0003001 generation of a signal involved in cell-cell signaling
4.92 5.64e-04 GO:0023061 signal release
2.74 1.01e-03 GO:0044057 regulation of system process
2.15 1.42e-03 GO:0006811 ion transport
6.34 1.56e-03 GO:0070588 calcium ion transmembrane transport
1.80 1.96e-03 GO:0065009 regulation of molecular function
2.35 2.29e-03 GO:0006812 cation transport
1.90 2.34e-03 GO:0007399 nervous system development
4.03 3.58e-03 GO:0015837 amine transport
2.57 3.98e-03 GO:0006873 cellular ion homeostasis
4.22 4.09e-03 GO:0007611 learning or memory
2.50 6.70e-03 GO:0055082 cellular chemical homeostasis
2.77 7.36e-03 GO:0051046 regulation of secretion
3.97 8.77e-03 GO:0050890 cognition
3.57 9.02e-03 GO:0071705 nitrogen compound transport
4.47 1.00e-02 GO:0006865 amino acid transport
23.82 1.31e-02 GO:0015812 gamma-aminobutyric acid transport
5.11 1.41e-02 GO:0048167 regulation of synaptic plasticity
3.57 1.69e-02 GO:0046942 carboxylic acid transport
3.75 1.78e-02 GO:0006816 calcium ion transport
3.53 1.97e-02 GO:0015849 organic acid transport
2.35 2.30e-02 GO:0050801 ion homeostasis
2.53 2.31e-02 GO:0007610 behavior
2.07 2.43e-02 GO:0055085 transmembrane transport
1.98 2.63e-02 GO:0022008 neurogenesis
6.81 2.74e-02 GO:0048489 synaptic vesicle transport
2.24 3.08e-02 GO:0019725 cellular homeostasis
2.64 3.82e-02 GO:0046903 secretion
6.50 3.92e-02 GO:0007270 nerve-nerve synaptic transmission
9.32 4.74e-02 GO:0017158 regulation of calcium ion-dependent exocytosis

Gene overrepresentation in compartment category:

enrichment p-value GO term description
1.41 2.72e-12 GO:0016020 membrane
3.60 4.04e-12 GO:0045202 synapse
1.74 4.98e-12 GO:0071944 cell periphery
1.74 7.27e-12 GO:0005886 plasma membrane
3.22 8.24e-11 GO:0043005 neuron projection
3.65 2.09e-08 GO:0044456 synapse part
1.32 6.64e-07 GO:0005737 cytoplasm
1.14 8.70e-07 GO:0005623 cell
1.14 8.70e-07 GO:0044464 cell part
2.14 2.51e-06 GO:0042995 cell projection
1.34 6.02e-06 GO:0044425 membrane part
3.39 9.27e-06 GO:0030425 dendrite
2.33 1.35e-05 GO:0031982 vesicle
1.39 1.78e-05 GO:0044444 cytoplasmic part
1.78 2.51e-05 GO:0044459 plasma membrane part
2.32 3.92e-05 GO:0031410 cytoplasmic vesicle
3.30 8.60e-05 GO:0030424 axon
1.95 1.00e-04 GO:0000267 cell fraction
1.20 2.31e-04 GO:0044424 intracellular part
1.19 3.32e-04 GO:0005622 intracellular
2.89 3.69e-04 GO:0043025 neuronal cell body
2.29 3.95e-04 GO:0030054 cell junction
2.42 5.35e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
6.62 5.46e-04 GO:0030665 clathrin coated vesicle membrane
3.92 8.75e-04 GO:0030136 clathrin-coated vesicle
2.75 9.04e-04 GO:0044297 cell body
4.69 9.76e-04 GO:0008021 synaptic vesicle
4.06 1.12e-03 GO:0033267 axon part
2.29 1.74e-03 GO:0031988 membrane-bounded vesicle
1.92 3.00e-03 GO:0005626 insoluble fraction
1.79 3.38e-03 GO:0031090 organelle membrane
3.45 4.54e-03 GO:0030135 coated vesicle
5.11 6.06e-03 GO:0030662 coated vesicle membrane
1.28 7.48e-03 GO:0016021 integral to membrane
4.90 8.81e-03 GO:0019897 extrinsic to plasma membrane
1.89 8.90e-03 GO:0005624 membrane fraction
3.42 9.16e-03 GO:0030659 cytoplasmic vesicle membrane
2.35 9.77e-03 GO:0044463 cell projection part
3.31 1.32e-02 GO:0044433 cytoplasmic vesicle part
1.92 1.40e-02 GO:0012505 endomembrane system
1.26 1.59e-02 GO:0031224 intrinsic to membrane
4.31 2.69e-02 GO:0014069 postsynaptic density
3.10 2.79e-02 GO:0012506 vesicle membrane
7.39 3.27e-02 GO:0030672 synaptic vesicle membrane
3.11 4.54e-02 GO:0045211 postsynaptic membrane
1.76 4.74e-02 GO:0005794 Golgi apparatus

Gene overrepresentation in function category:

enrichment p-value GO term description
1.49 3.14e-09 GO:0005515 protein binding
4.94 2.23e-05 GO:0005516 calmodulin binding
3.42 6.64e-05 GO:0005261 cation channel activity
2.25 7.99e-05 GO:0022891 substrate-specific transmembrane transporter activity
2.61 1.01e-04 GO:0008324 cation transmembrane transporter activity
2.12 2.57e-04 GO:0022857 transmembrane transporter activity
1.19 3.92e-04 GO:0005488 binding
2.74 5.98e-04 GO:0005216 ion channel activity
2.04 7.07e-04 GO:0022892 substrate-specific transporter activity
2.68 9.12e-04 GO:0022838 substrate-specific channel activity
2.20 1.10e-03 GO:0015075 ion transmembrane transporter activity
2.60 1.67e-03 GO:0015267 channel activity
2.59 1.76e-03 GO:0022803 passive transmembrane transporter activity
5.46 1.81e-03 GO:0005262 calcium channel activity
1.90 1.88e-03 GO:0005215 transporter activity
2.30 3.45e-03 GO:0019904 protein domain specific binding
2.83 4.81e-03 GO:0022836 gated channel activity
4.77 1.66e-02 GO:0005275 amine transmembrane transporter activity
7.15 1.66e-02 GO:0019905 syntaxin binding
3.18 1.82e-02 GO:0005244 voltage-gated ion channel activity
3.18 1.82e-02 GO:0022832 voltage-gated channel activity
5.11 2.29e-02 GO:0015171 amino acid transmembrane transporter activity
9.93 4.04e-02 GO:0004683 calmodulin-dependent protein kinase activity